---
_id: '60047'
abstract:
- lang: eng
text: "Abstract\r\n Purpose\r\n
\ Cardiopulmonary exercise testing (CPET) is considered
the gold standard for assessing cardiorespiratory fitness. To ensure consistent
performance of each test, it is necessary to adapt the power increase of the test
protocol to the physical characteristics of each individual. This study aimed
to use machine learning models to determine individualized ramp protocols based
on non-exercise features. We hypothesized that machine learning models will predict
peak oxygen uptake ($$\\dot{V}$$\r\n \r\n
\ V\r\n ˙\r\n
\ \r\n O2peak)
and peak power output (PPO) more accurately than conventional multiple linear
regression (MLR).\r\n \r\n Methods\r\n
\ The cross-sectional study was conducted with 274 (♀168,
♂106) participants who performed CPET on a cycle ergometer. Machine learning models
and multiple linear regression were used to predict $$\\dot{V}$$\r\n \r\n
\ V\r\n ˙\r\n
\ \r\n O2peak
and PPO using non-exercise features. The accuracy of the models was compared using
criteria such as root mean square error (RMSE). Shapley additive explanation (SHAP)
was applied to determine the feature importance.\r\n \r\n
\ Results\r\n The
most accurate machine learning model was the random forest (RMSE: 6.52 ml/kg/min
[95% CI 5.21–8.17]) for $$\\dot{V}$$\r\n \r\n
\ V\r\n ˙\r\n
\ \r\n O2peak
prediction and the gradient boosting regression (RMSE: 43watts [95% CI 35–52])
for PPO prediction. Compared to the MLR, the machine learning models reduced the
RMSE by up to 28% and 22% for prediction of $$\\dot{V}$$\r\n \r\n
\ V\r\n ˙\r\n
\ \r\n O2peak
and PPO, respectively. Furthermore, SHAP ranked body composition data such as
skeletal muscle mass and extracellular water as the most impactful features.\r\n
\ \r\n Conclusion\r\n
\ Machine learning models predict $$\\dot{V}$$\r\n \r\n
\ V\r\n ˙\r\n
\ \r\n O2peak
and PPO more accurately than MLR and can be used to individualize CPET protocols.
Features that provide information about the participant's body composition contribute
most to the improvement of these predictions.\r\n \r\n
\ Trial registration number\r\n DRKS00031401
(6 March 2023, retrospectively registered).\r\n "
author:
- first_name: Charlotte
full_name: Wenzel, Charlotte
last_name: Wenzel
- first_name: Thomas
full_name: Liebig, Thomas
last_name: Liebig
- first_name: Adrian
full_name: Swoboda, Adrian
last_name: Swoboda
- first_name: Rika
full_name: Smolareck, Rika
last_name: Smolareck
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Andreas
full_name: Groll, Andreas
last_name: Groll
- first_name: Richie P.
full_name: Goulding, Richie P.
last_name: Goulding
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Wenzel C, Liebig T, Swoboda A, et al. Machine learning predicts peak oxygen
uptake and peak power output for customizing cardiopulmonary exercise testing
using non-exercise features. European Journal of Applied Physiology. 2024;124(11):3421-3431.
doi:10.1007/s00421-024-05543-x
apa: Wenzel, C., Liebig, T., Swoboda, A., Smolareck, R., Schlagheck, M. L., Walzik,
D., Groll, A., Goulding, R. P., & Zimmer, P. (2024). Machine learning predicts
peak oxygen uptake and peak power output for customizing cardiopulmonary exercise
testing using non-exercise features. European Journal of Applied Physiology,
124(11), 3421–3431. https://doi.org/10.1007/s00421-024-05543-x
bibtex: '@article{Wenzel_Liebig_Swoboda_Smolareck_Schlagheck_Walzik_Groll_Goulding_Zimmer_2024,
title={Machine learning predicts peak oxygen uptake and peak power output for
customizing cardiopulmonary exercise testing using non-exercise features}, volume={124},
DOI={10.1007/s00421-024-05543-x},
number={11}, journal={European Journal of Applied Physiology}, publisher={Springer
Science and Business Media LLC}, author={Wenzel, Charlotte and Liebig, Thomas
and Swoboda, Adrian and Smolareck, Rika and Schlagheck, Marit Lea and Walzik,
David and Groll, Andreas and Goulding, Richie P. and Zimmer, Philipp}, year={2024},
pages={3421–3431} }'
chicago: 'Wenzel, Charlotte, Thomas Liebig, Adrian Swoboda, Rika Smolareck, Marit
Lea Schlagheck, David Walzik, Andreas Groll, Richie P. Goulding, and Philipp Zimmer.
“Machine Learning Predicts Peak Oxygen Uptake and Peak Power Output for Customizing
Cardiopulmonary Exercise Testing Using Non-Exercise Features.” European Journal
of Applied Physiology 124, no. 11 (2024): 3421–31. https://doi.org/10.1007/s00421-024-05543-x.'
ieee: 'C. Wenzel et al., “Machine learning predicts peak oxygen uptake and
peak power output for customizing cardiopulmonary exercise testing using non-exercise
features,” European Journal of Applied Physiology, vol. 124, no. 11, pp.
3421–3431, 2024, doi: 10.1007/s00421-024-05543-x.'
mla: Wenzel, Charlotte, et al. “Machine Learning Predicts Peak Oxygen Uptake and
Peak Power Output for Customizing Cardiopulmonary Exercise Testing Using Non-Exercise
Features.” European Journal of Applied Physiology, vol. 124, no. 11, Springer
Science and Business Media LLC, 2024, pp. 3421–31, doi:10.1007/s00421-024-05543-x.
short: C. Wenzel, T. Liebig, A. Swoboda, R. Smolareck, M.L. Schlagheck, D. Walzik,
A. Groll, R.P. Goulding, P. Zimmer, European Journal of Applied Physiology 124
(2024) 3421–3431.
date_created: 2025-05-27T07:54:52Z
date_updated: 2025-06-02T09:34:21Z
doi: 10.1007/s00421-024-05543-x
extern: '1'
intvolume: ' 124'
issue: '11'
language:
- iso: eng
page: 3421-3431
publication: European Journal of Applied Physiology
publication_identifier:
issn:
- 1439-6319
- 1439-6327
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Machine learning predicts peak oxygen uptake and peak power output for customizing
cardiopulmonary exercise testing using non-exercise features
type: journal_article
user_id: '117661'
volume: 124
year: '2024'
...
---
_id: '60092'
abstract:
- lang: eng
text: "Abstract\r\n Purpose\r\n
\ Research supports physical activity as a method to heighten
stress resistance and resilience through positive metabolic alterations mostly
affecting the neuroendocrine system. High-intensity interval training (HIIT) has
been proposed as a highly effective time-saving method to induce those changes.
However, existing literature relies heavily on cross-sectional analyses, with
few randomised controlled trials highlighting the necessity for more exercise
interventions. Thus, this study aims to investigate the effects of HIIT versus
an active control group on the stress response to an acute psychosocial stressor
in emotionally impulsive humans (suggested as being strong stress responders).\r\n
\ \r\n Methods\r\n
\ The study protocol was registered online (DRKS00016589)
before data collection. Sedentary, emotionally impulsive adults (30.69 ± 8.20
y) were recruited for a supervised intervention of 8 weeks and randomly allocated
to either a HIIT (n = 25) or a stretching group (n = 19,
acting as active controls). Participants were submitted to a test battery, including
saliva samples, questionnaires (self-efficacy- and perceived stress-related),
visual analogue scales (physical exercise- and stress-related), and resting electroencephalography
and electrocardiography assessing their reaction to an acute psychological stressor
(Trier Social Stress Test) before and after the exercise intervention.\r\n
\ \r\n Results\r\n
\ HIIT increased aerobic fitness in all participants, whereas
stretching did not. Participants from the HIIT group reported perceiving exercising
more intensively than those from the active control group (ƞp2 = 0.108,
p = 0.038). No further group differences were detected.
Both interventions largely increased levels of joy post-TSST (ƞp2 = 0.209,
p = 0.003) whilst decreasing tension (ƞp2 = 0.262,
p < 0.001) and worries (ƞp2 = 0.113,
p = 0.037). Finally, both interventions largely increased
perceived levels of general self-efficacy (ƞp2 = 0.120,
p = 0.029).\r\n \r\n
\ Conclusion\r\n This
study suggests that 8 weeks of HIIT does not change the psychoneuroendocrine response
to an acute psychological stress test compared to an active control group in emotionally
impulsive humans. Further replications of supervised exercise studies highly powered
with active and passive controls are warranted.\r\n "
author:
- first_name: F.
full_name: Javelle, F.
last_name: Javelle
- first_name: W.
full_name: Bloch, W.
last_name: Bloch
- first_name: U.
full_name: Borges, U.
last_name: Borges
- first_name: T.
full_name: Burberg, T.
last_name: Burberg
- first_name: B.
full_name: Collins, B.
last_name: Collins
- first_name: N.
full_name: Gunasekara, N.
last_name: Gunasekara
- first_name: T. J.
full_name: Hosang, T. J.
last_name: Hosang
- first_name: T.
full_name: Jacobsen, T.
last_name: Jacobsen
- first_name: S.
full_name: Laborde, S.
last_name: Laborde
- first_name: A.
full_name: Löw, A.
last_name: Löw
- first_name: A.
full_name: Schenk, A.
last_name: Schenk
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: D.
full_name: Schoser, D.
last_name: Schoser
- first_name: A.
full_name: Vogel, A.
last_name: Vogel
- first_name: D.
full_name: Walzik, D.
last_name: Walzik
- first_name: P.
full_name: Zimmer, P.
last_name: Zimmer
citation:
ama: Javelle F, Bloch W, Borges U, et al. Eight weeks of high-intensity interval
training versus stretching do not change the psychoneuroendocrine response to
a social stress test in emotionally impulsive humans. European Journal of Applied
Physiology. 2024;124(10):2893-2908. doi:10.1007/s00421-024-05471-w
apa: Javelle, F., Bloch, W., Borges, U., Burberg, T., Collins, B., Gunasekara, N.,
Hosang, T. J., Jacobsen, T., Laborde, S., Löw, A., Schenk, A., Schlagheck, M.
L., Schoser, D., Vogel, A., Walzik, D., & Zimmer, P. (2024). Eight weeks of
high-intensity interval training versus stretching do not change the psychoneuroendocrine
response to a social stress test in emotionally impulsive humans. European
Journal of Applied Physiology, 124(10), 2893–2908. https://doi.org/10.1007/s00421-024-05471-w
bibtex: '@article{Javelle_Bloch_Borges_Burberg_Collins_Gunasekara_Hosang_Jacobsen_Laborde_Löw_et
al._2024, title={Eight weeks of high-intensity interval training versus stretching
do not change the psychoneuroendocrine response to a social stress test in emotionally
impulsive humans}, volume={124}, DOI={10.1007/s00421-024-05471-w},
number={10}, journal={European Journal of Applied Physiology}, publisher={Springer
Science and Business Media LLC}, author={Javelle, F. and Bloch, W. and Borges,
U. and Burberg, T. and Collins, B. and Gunasekara, N. and Hosang, T. J. and Jacobsen,
T. and Laborde, S. and Löw, A. and et al.}, year={2024}, pages={2893–2908} }'
chicago: 'Javelle, F., W. Bloch, U. Borges, T. Burberg, B. Collins, N. Gunasekara,
T. J. Hosang, et al. “Eight Weeks of High-Intensity Interval Training versus Stretching
Do Not Change the Psychoneuroendocrine Response to a Social Stress Test in Emotionally
Impulsive Humans.” European Journal of Applied Physiology 124, no. 10 (2024):
2893–2908. https://doi.org/10.1007/s00421-024-05471-w.'
ieee: 'F. Javelle et al., “Eight weeks of high-intensity interval training
versus stretching do not change the psychoneuroendocrine response to a social
stress test in emotionally impulsive humans,” European Journal of Applied Physiology,
vol. 124, no. 10, pp. 2893–2908, 2024, doi: 10.1007/s00421-024-05471-w.'
mla: Javelle, F., et al. “Eight Weeks of High-Intensity Interval Training versus
Stretching Do Not Change the Psychoneuroendocrine Response to a Social Stress
Test in Emotionally Impulsive Humans.” European Journal of Applied Physiology,
vol. 124, no. 10, Springer Science and Business Media LLC, 2024, pp. 2893–908,
doi:10.1007/s00421-024-05471-w.
short: F. Javelle, W. Bloch, U. Borges, T. Burberg, B. Collins, N. Gunasekara, T.J.
Hosang, T. Jacobsen, S. Laborde, A. Löw, A. Schenk, M.L. Schlagheck, D. Schoser,
A. Vogel, D. Walzik, P. Zimmer, European Journal of Applied Physiology 124 (2024)
2893–2908.
date_created: 2025-06-02T09:43:08Z
date_updated: 2025-06-02T09:44:49Z
doi: 10.1007/s00421-024-05471-w
extern: '1'
intvolume: ' 124'
issue: '10'
language:
- iso: eng
page: 2893-2908
publication: European Journal of Applied Physiology
publication_identifier:
issn:
- 1439-6319
- 1439-6327
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Eight weeks of high-intensity interval training versus stretching do not change
the psychoneuroendocrine response to a social stress test in emotionally impulsive
humans
type: journal_article
user_id: '117661'
volume: 124
year: '2024'
...
---
_id: '60093'
author:
- first_name: Sebastian
full_name: Proschinger, Sebastian
last_name: Proschinger
- first_name: Sergen
full_name: Belen, Sergen
last_name: Belen
- first_name: Frederike
full_name: Adammek, Frederike
last_name: Adammek
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Alexander
full_name: Schenk, Alexander
last_name: Schenk
- first_name: Clemens
full_name: Warnke, Clemens
last_name: Warnke
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: 'Proschinger S, Belen S, Adammek F, et al. Sportizumab – Multimodal progressive
exercise over 10 weeks decreases Th17 frequency and CD49d expression on CD8+ T
cells in relapsing-remitting multiple sclerosis: A randomized controlled trial.
Brain, Behavior, and Immunity. 2024;124:397-408. doi:10.1016/j.bbi.2024.12.017'
apa: 'Proschinger, S., Belen, S., Adammek, F., Schlagheck, M. L., Rademacher, A.,
Schenk, A., Warnke, C., Bloch, W., & Zimmer, P. (2024). Sportizumab – Multimodal
progressive exercise over 10 weeks decreases Th17 frequency and CD49d expression
on CD8+ T cells in relapsing-remitting multiple sclerosis: A randomized controlled
trial. Brain, Behavior, and Immunity, 124, 397–408. https://doi.org/10.1016/j.bbi.2024.12.017'
bibtex: '@article{Proschinger_Belen_Adammek_Schlagheck_Rademacher_Schenk_Warnke_Bloch_Zimmer_2024,
title={Sportizumab – Multimodal progressive exercise over 10 weeks decreases Th17
frequency and CD49d expression on CD8+ T cells in relapsing-remitting multiple
sclerosis: A randomized controlled trial}, volume={124}, DOI={10.1016/j.bbi.2024.12.017},
journal={Brain, Behavior, and Immunity}, publisher={Elsevier BV}, author={Proschinger,
Sebastian and Belen, Sergen and Adammek, Frederike and Schlagheck, Marit Lea and
Rademacher, Annette and Schenk, Alexander and Warnke, Clemens and Bloch, Wilhelm
and Zimmer, Philipp}, year={2024}, pages={397–408} }'
chicago: 'Proschinger, Sebastian, Sergen Belen, Frederike Adammek, Marit Lea Schlagheck,
Annette Rademacher, Alexander Schenk, Clemens Warnke, Wilhelm Bloch, and Philipp
Zimmer. “Sportizumab – Multimodal Progressive Exercise over 10 Weeks Decreases
Th17 Frequency and CD49d Expression on CD8+ T Cells in Relapsing-Remitting Multiple
Sclerosis: A Randomized Controlled Trial.” Brain, Behavior, and Immunity
124 (2024): 397–408. https://doi.org/10.1016/j.bbi.2024.12.017.'
ieee: 'S. Proschinger et al., “Sportizumab – Multimodal progressive exercise
over 10 weeks decreases Th17 frequency and CD49d expression on CD8+ T cells in
relapsing-remitting multiple sclerosis: A randomized controlled trial,” Brain,
Behavior, and Immunity, vol. 124, pp. 397–408, 2024, doi: 10.1016/j.bbi.2024.12.017.'
mla: 'Proschinger, Sebastian, et al. “Sportizumab – Multimodal Progressive Exercise
over 10 Weeks Decreases Th17 Frequency and CD49d Expression on CD8+ T Cells in
Relapsing-Remitting Multiple Sclerosis: A Randomized Controlled Trial.” Brain,
Behavior, and Immunity, vol. 124, Elsevier BV, 2024, pp. 397–408, doi:10.1016/j.bbi.2024.12.017.'
short: S. Proschinger, S. Belen, F. Adammek, M.L. Schlagheck, A. Rademacher, A.
Schenk, C. Warnke, W. Bloch, P. Zimmer, Brain, Behavior, and Immunity 124 (2024)
397–408.
date_created: 2025-06-02T09:48:43Z
date_updated: 2025-06-02T09:53:19Z
doi: 10.1016/j.bbi.2024.12.017
extern: '1'
intvolume: ' 124'
language:
- iso: eng
page: 397-408
publication: Brain, Behavior, and Immunity
publication_identifier:
issn:
- 0889-1591
publication_status: published
publisher: Elsevier BV
status: public
title: 'Sportizumab – Multimodal progressive exercise over 10 weeks decreases Th17
frequency and CD49d expression on CD8+ T cells in relapsing-remitting multiple sclerosis:
A randomized controlled trial'
type: journal_article
user_id: '117661'
volume: 124
year: '2024'
...
---
_id: '60094'
article_number: '105826'
author:
- first_name: Nadine
full_name: Patt, Nadine
last_name: Patt
- first_name: Marie
full_name: Kupjetz, Marie
last_name: Kupjetz
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Ruth
full_name: Hersche, Ruth
last_name: Hersche
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Jan
full_name: Kool, Jan
last_name: Kool
- first_name: Roman
full_name: Gonzenbach, Roman
last_name: Gonzenbach
- first_name: Claudio R.
full_name: Nigg, Claudio R.
last_name: Nigg
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
citation:
ama: 'Patt N, Kupjetz M, Schlagheck ML, et al. Predictors of six-month change in
health-related quality of life in people with multiple sclerosis: A secondary
data analysis of a randomized controlled trial. Multiple Sclerosis and Related
Disorders. 2024;90. doi:10.1016/j.msard.2024.105826'
apa: 'Patt, N., Kupjetz, M., Schlagheck, M. L., Hersche, R., Joisten, N., Kool,
J., Gonzenbach, R., Nigg, C. R., Zimmer, P., & Bansi, J. (2024). Predictors
of six-month change in health-related quality of life in people with multiple
sclerosis: A secondary data analysis of a randomized controlled trial. Multiple
Sclerosis and Related Disorders, 90, Article 105826. https://doi.org/10.1016/j.msard.2024.105826'
bibtex: '@article{Patt_Kupjetz_Schlagheck_Hersche_Joisten_Kool_Gonzenbach_Nigg_Zimmer_Bansi_2024,
title={Predictors of six-month change in health-related quality of life in people
with multiple sclerosis: A secondary data analysis of a randomized controlled
trial}, volume={90}, DOI={10.1016/j.msard.2024.105826},
number={105826}, journal={Multiple Sclerosis and Related Disorders}, publisher={Elsevier
BV}, author={Patt, Nadine and Kupjetz, Marie and Schlagheck, Marit Lea and Hersche,
Ruth and Joisten, Niklas and Kool, Jan and Gonzenbach, Roman and Nigg, Claudio
R. and Zimmer, Philipp and Bansi, Jens}, year={2024} }'
chicago: 'Patt, Nadine, Marie Kupjetz, Marit Lea Schlagheck, Ruth Hersche, Niklas
Joisten, Jan Kool, Roman Gonzenbach, Claudio R. Nigg, Philipp Zimmer, and Jens
Bansi. “Predictors of Six-Month Change in Health-Related Quality of Life in People
with Multiple Sclerosis: A Secondary Data Analysis of a Randomized Controlled
Trial.” Multiple Sclerosis and Related Disorders 90 (2024). https://doi.org/10.1016/j.msard.2024.105826.'
ieee: 'N. Patt et al., “Predictors of six-month change in health-related
quality of life in people with multiple sclerosis: A secondary data analysis of
a randomized controlled trial,” Multiple Sclerosis and Related Disorders,
vol. 90, Art. no. 105826, 2024, doi: 10.1016/j.msard.2024.105826.'
mla: 'Patt, Nadine, et al. “Predictors of Six-Month Change in Health-Related Quality
of Life in People with Multiple Sclerosis: A Secondary Data Analysis of a Randomized
Controlled Trial.” Multiple Sclerosis and Related Disorders, vol. 90, 105826,
Elsevier BV, 2024, doi:10.1016/j.msard.2024.105826.'
short: N. Patt, M. Kupjetz, M.L. Schlagheck, R. Hersche, N. Joisten, J. Kool, R.
Gonzenbach, C.R. Nigg, P. Zimmer, J. Bansi, Multiple Sclerosis and Related Disorders
90 (2024).
date_created: 2025-06-02T09:49:06Z
date_updated: 2025-06-02T09:53:01Z
doi: 10.1016/j.msard.2024.105826
extern: '1'
intvolume: ' 90'
language:
- iso: eng
publication: Multiple Sclerosis and Related Disorders
publication_identifier:
issn:
- 2211-0348
publication_status: published
publisher: Elsevier BV
status: public
title: 'Predictors of six-month change in health-related quality of life in people
with multiple sclerosis: A secondary data analysis of a randomized controlled trial'
type: journal_article
user_id: '117661'
volume: 90
year: '2024'
...
---
_id: '60046'
abstract:
- lang: eng
text: AbstractBackground and purposeValid
measurements of cardiorespiratory fitness in persons with multiple sclerosis (pwMS)
are essential during inpatient rehabilitation for a precise evaluation of the
current health status, for defining appropriate exercise intensities, and for
evaluation of exercise intervention studies. We aim (i) to examine the proportion
of pwMS who attain the American College of Sports Medicine (ACSM) criteria for
maximal effort during graded cardiopulmonary exercise testing (CPET) and (ii)
to provide insight into participant characteristics that limit maximal exercise
performance.MethodsThis
cross‐sectional study comprises a retrospective examination of ACSM criteria for
maximal effort during graded CPET of n = 380 inpatient
pwMS (mean age = 48 ± 11 years, 66% female). Chi‐squared or Fisher's exact tests
were conducted to compare differences in the distribution of criteria achieved.
Participants' characteristics were examined as potential predictors using binary
logistic regression.ResultsOnly
60% of the overall sample attained a respiratory exchange ratio ≥ 1.10. With regard
to the definition applied, only 24% or 40% of the participants achieved an oxygen
consumption plateau, and 17% or 50% attained the heart rate criterion. Forty‐six
percent met at least two of three criteria. Disability status, gender, disease
course, and body mass index were associated with the attainment of maximal effort.ConclusionsOur
findings suggest that a relevant proportion of inpatient pwMS do not attain common
criteria utilized to verify maximal oxygen consumption. Identified predictors
for criteria attainment can be used to create models to predict cardiorespiratory
fitness and to optimize CPET protocols in restrictive groups of pwMS.
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Charlotte
full_name: Wenzel, Charlotte
last_name: Wenzel
- first_name: Marina
full_name: Kuzdas‐Sallaberger, Marina
last_name: Kuzdas‐Sallaberger
- first_name: David
full_name: Kiesl, David
last_name: Kiesl
- first_name: Roman
full_name: Gonzenbach, Roman
last_name: Gonzenbach
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Schlagheck ML, Bansi J, Wenzel C, et al. Complexity and pitfalls in maximal
exercise testing for persons with multiple sclerosis. European Journal of Neurology.
2023;30(9):2726-2735. doi:10.1111/ene.15875
apa: Schlagheck, M. L., Bansi, J., Wenzel, C., Kuzdas‐Sallaberger, M., Kiesl, D.,
Gonzenbach, R., & Zimmer, P. (2023). Complexity and pitfalls in maximal exercise
testing for persons with multiple sclerosis. European Journal of Neurology,
30(9), 2726–2735. https://doi.org/10.1111/ene.15875
bibtex: '@article{Schlagheck_Bansi_Wenzel_Kuzdas‐Sallaberger_Kiesl_Gonzenbach_Zimmer_2023,
title={Complexity and pitfalls in maximal exercise testing for persons with multiple
sclerosis}, volume={30}, DOI={10.1111/ene.15875},
number={9}, journal={European Journal of Neurology}, publisher={Wiley}, author={Schlagheck,
Marit Lea and Bansi, Jens and Wenzel, Charlotte and Kuzdas‐Sallaberger, Marina
and Kiesl, David and Gonzenbach, Roman and Zimmer, Philipp}, year={2023}, pages={2726–2735}
}'
chicago: 'Schlagheck, Marit Lea, Jens Bansi, Charlotte Wenzel, Marina Kuzdas‐Sallaberger,
David Kiesl, Roman Gonzenbach, and Philipp Zimmer. “Complexity and Pitfalls in
Maximal Exercise Testing for Persons with Multiple Sclerosis.” European Journal
of Neurology 30, no. 9 (2023): 2726–35. https://doi.org/10.1111/ene.15875.'
ieee: 'M. L. Schlagheck et al., “Complexity and pitfalls in maximal exercise
testing for persons with multiple sclerosis,” European Journal of Neurology,
vol. 30, no. 9, pp. 2726–2735, 2023, doi: 10.1111/ene.15875.'
mla: Schlagheck, Marit Lea, et al. “Complexity and Pitfalls in Maximal Exercise
Testing for Persons with Multiple Sclerosis.” European Journal of Neurology,
vol. 30, no. 9, Wiley, 2023, pp. 2726–35, doi:10.1111/ene.15875.
short: M.L. Schlagheck, J. Bansi, C. Wenzel, M. Kuzdas‐Sallaberger, D. Kiesl, R.
Gonzenbach, P. Zimmer, European Journal of Neurology 30 (2023) 2726–2735.
date_created: 2025-05-27T07:54:42Z
date_updated: 2025-06-02T09:34:01Z
doi: 10.1111/ene.15875
extern: '1'
intvolume: ' 30'
issue: '9'
language:
- iso: eng
page: 2726-2735
publication: European Journal of Neurology
publication_identifier:
issn:
- 1351-5101
- 1468-1331
publication_status: published
publisher: Wiley
status: public
title: Complexity and pitfalls in maximal exercise testing for persons with multiple
sclerosis
type: journal_article
user_id: '117661'
volume: 30
year: '2023'
...
---
_id: '60087'
abstract:
- lang: eng
text: IntroductionBased on theoretical
models, physical activity has been introduced as a promoting method to mitigate
the disease severity, fatigue and relapse rate in multiple sclerosis. The primary
objective of the study was to investigate the relation between self-reported physical
activity level and disease severity, fatigue and relapse rate in persons with
relapsing remitting multiple sclerosis (RRMS).MethodsA
survey was offered to persons with RRMS from March 2019 to August 2021 (n = 253).
Physical activity level, fatigue and disease severity were determined using the
Godin Leisure-Time Questionnaire (GLTEQ), the Patient Determined Disease Steps
(PDDS) scale and the Fatigue Scale for Motor and Cognitive Functions (FSMC). Additionally,
participants’ relapse rate was recorded.ResultsBivariate
correlations revealed an inverse relation between physical activity level and
PDDS (ρ = −0.279; p < 0.001)
as well as between physical activity and FSMC (r = −0.213,
p < 0.001), but not between physical activity
and relapse rate (r = 0.033, p > 0.05).
Multiple linear regression analyses explained 12.6% and 5.2% of the variance of
PDDS and FSMC.ConclusionOur
findings confirm a relation between self-reported physical activity, disease severity
and fatigue in persons with RRMS. However, self-reported physical activity level
does not seem to affect the annualised relapse rate.
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Sven T.
full_name: Hübner, Sven T.
last_name: Hübner
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Florian
full_name: Wolf, Florian
last_name: Wolf
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Clemens
full_name: Warnke, Clemens
last_name: Warnke
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Schlagheck ML, Hübner ST, Joisten N, et al. Physical activity is related to
disease severity and fatigue, but not to relapse rate in persons with relapsing
remitting multiple sclerosis – a self-reported questionnaire based study. Frontiers
in Neurology. 2023;14. doi:10.3389/fneur.2023.1217000
apa: Schlagheck, M. L., Hübner, S. T., Joisten, N., Walzik, D., Rademacher, A.,
Wolf, F., Bansi, J., Warnke, C., & Zimmer, P. (2023). Physical activity is
related to disease severity and fatigue, but not to relapse rate in persons with
relapsing remitting multiple sclerosis – a self-reported questionnaire based study.
Frontiers in Neurology, 14. https://doi.org/10.3389/fneur.2023.1217000
bibtex: '@article{Schlagheck_Hübner_Joisten_Walzik_Rademacher_Wolf_Bansi_Warnke_Zimmer_2023,
title={Physical activity is related to disease severity and fatigue, but not to
relapse rate in persons with relapsing remitting multiple sclerosis – a self-reported
questionnaire based study}, volume={14}, DOI={10.3389/fneur.2023.1217000},
journal={Frontiers in Neurology}, publisher={Frontiers Media SA}, author={Schlagheck,
Marit Lea and Hübner, Sven T. and Joisten, Niklas and Walzik, David and Rademacher,
Annette and Wolf, Florian and Bansi, Jens and Warnke, Clemens and Zimmer, Philipp},
year={2023} }'
chicago: Schlagheck, Marit Lea, Sven T. Hübner, Niklas Joisten, David Walzik, Annette
Rademacher, Florian Wolf, Jens Bansi, Clemens Warnke, and Philipp Zimmer. “Physical
Activity Is Related to Disease Severity and Fatigue, but Not to Relapse Rate in
Persons with Relapsing Remitting Multiple Sclerosis – a Self-Reported Questionnaire
Based Study.” Frontiers in Neurology 14 (2023). https://doi.org/10.3389/fneur.2023.1217000.
ieee: 'M. L. Schlagheck et al., “Physical activity is related to disease
severity and fatigue, but not to relapse rate in persons with relapsing remitting
multiple sclerosis – a self-reported questionnaire based study,” Frontiers
in Neurology, vol. 14, 2023, doi: 10.3389/fneur.2023.1217000.'
mla: Schlagheck, Marit Lea, et al. “Physical Activity Is Related to Disease Severity
and Fatigue, but Not to Relapse Rate in Persons with Relapsing Remitting Multiple
Sclerosis – a Self-Reported Questionnaire Based Study.” Frontiers in Neurology,
vol. 14, Frontiers Media SA, 2023, doi:10.3389/fneur.2023.1217000.
short: M.L. Schlagheck, S.T. Hübner, N. Joisten, D. Walzik, A. Rademacher, F. Wolf,
J. Bansi, C. Warnke, P. Zimmer, Frontiers in Neurology 14 (2023).
date_created: 2025-06-02T09:36:45Z
date_updated: 2025-06-02T09:47:09Z
doi: 10.3389/fneur.2023.1217000
extern: '1'
intvolume: ' 14'
language:
- iso: eng
publication: Frontiers in Neurology
publication_identifier:
issn:
- 1664-2295
publication_status: published
publisher: Frontiers Media SA
status: public
title: Physical activity is related to disease severity and fatigue, but not to relapse
rate in persons with relapsing remitting multiple sclerosis – a self-reported questionnaire
based study
type: journal_article
user_id: '117661'
volume: 14
year: '2023'
...
---
_id: '60091'
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Martin
full_name: Langeskov-Christensen, Martin
last_name: Langeskov-Christensen
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
- first_name: Lars G.
full_name: Hvid, Lars G.
last_name: Hvid
citation:
ama: Schlagheck ML, Bansi J, Langeskov-Christensen M, Zimmer P, Hvid LG. Cardiorespiratory
fitness (V̇O2peak) across the adult lifespan in persons with multiple sclerosis
and matched healthy controls. Journal of Science and Medicine in Sport.
2023;27(1):10-15. doi:10.1016/j.jsams.2023.10.009
apa: Schlagheck, M. L., Bansi, J., Langeskov-Christensen, M., Zimmer, P., &
Hvid, L. G. (2023). Cardiorespiratory fitness (V̇O2peak) across the adult lifespan
in persons with multiple sclerosis and matched healthy controls. Journal of
Science and Medicine in Sport, 27(1), 10–15. https://doi.org/10.1016/j.jsams.2023.10.009
bibtex: '@article{Schlagheck_Bansi_Langeskov-Christensen_Zimmer_Hvid_2023, title={Cardiorespiratory
fitness (V̇O2peak) across the adult lifespan in persons with multiple sclerosis
and matched healthy controls}, volume={27}, DOI={10.1016/j.jsams.2023.10.009},
number={1}, journal={Journal of Science and Medicine in Sport}, publisher={Elsevier
BV}, author={Schlagheck, Marit Lea and Bansi, Jens and Langeskov-Christensen,
Martin and Zimmer, Philipp and Hvid, Lars G.}, year={2023}, pages={10–15} }'
chicago: 'Schlagheck, Marit Lea, Jens Bansi, Martin Langeskov-Christensen, Philipp
Zimmer, and Lars G. Hvid. “Cardiorespiratory Fitness (V̇O2peak) across the Adult
Lifespan in Persons with Multiple Sclerosis and Matched Healthy Controls.” Journal
of Science and Medicine in Sport 27, no. 1 (2023): 10–15. https://doi.org/10.1016/j.jsams.2023.10.009.'
ieee: 'M. L. Schlagheck, J. Bansi, M. Langeskov-Christensen, P. Zimmer, and L. G.
Hvid, “Cardiorespiratory fitness (V̇O2peak) across the adult lifespan in persons
with multiple sclerosis and matched healthy controls,” Journal of Science and
Medicine in Sport, vol. 27, no. 1, pp. 10–15, 2023, doi: 10.1016/j.jsams.2023.10.009.'
mla: Schlagheck, Marit Lea, et al. “Cardiorespiratory Fitness (V̇O2peak) across
the Adult Lifespan in Persons with Multiple Sclerosis and Matched Healthy Controls.”
Journal of Science and Medicine in Sport, vol. 27, no. 1, Elsevier BV,
2023, pp. 10–15, doi:10.1016/j.jsams.2023.10.009.
short: M.L. Schlagheck, J. Bansi, M. Langeskov-Christensen, P. Zimmer, L.G. Hvid,
Journal of Science and Medicine in Sport 27 (2023) 10–15.
date_created: 2025-06-02T09:42:26Z
date_updated: 2025-06-02T09:45:06Z
doi: 10.1016/j.jsams.2023.10.009
extern: '1'
intvolume: ' 27'
issue: '1'
language:
- iso: eng
page: 10-15
publication: Journal of Science and Medicine in Sport
publication_identifier:
issn:
- 1440-2440
publication_status: published
publisher: Elsevier BV
status: public
title: Cardiorespiratory fitness (V̇O2peak) across the adult lifespan in persons with
multiple sclerosis and matched healthy controls
type: journal_article
user_id: '117661'
volume: 27
year: '2023'
...
---
_id: '60095'
abstract:
- lang: eng
text: "AbstractEndurance training has been shown
to be effective in treating adolescents with major depressive disorder (MDD).
To integrate endurance training into the therapeutic setting and the adolescents'
daily lives, the current performance status of the adolescents should be accurately
assessed. This study aims to examine adolescents with MDD concerning exhaustion
criteria during a cardiopulmonary exercise test (CPET), as well as to compare
the values obtained thereon with sex- and age-related control values. The study
included a retrospective examination of exhaustion criteria ((i) oxygen consumption
(V̇O2) plateau, (ii) peak respiratory exchange ratio (RERpeak) > 1.0,
(iii) peak heart rate (HRpeak) ≥ 95% of the age-predicted
maximal HR, and (iv) peak blood lactate concentration (BLCpeak) > 8.0 mmol⋅L−1)
during a graded CPET on a cycle ergometer in adolescents with MDD (n = 57). Subsequently,
maximal V̇O2, peak minute ventilation, V̇O2
at the first ventilatory threshold, and peak work rate of participants who met
at least two of four criteria were compared with published control values using
an independent-sample t-test. Thirty-three percent of the total population achieved
a V̇O2 plateau and 75% a RERpeak > 1.0.
The HR and BLC criteria were met by 19% and 22%, respectively. T-test results
revealed significant differences between adolescents with MDD and control values
for all outcomes. Adolescents with MDD achieved between 56% and 83% of control
values. Conclusions: The study shows
that compared with control values, fewer adolescents with MDD achieve the exhaustion
criteria on a CPET and adolescents with MDD have significantly lower cardiorespiratory
fitness. Clinical trial registration:
No. U1111-1145–1854.\r\n
\ \r\n What
is Known:• It is already known that endurance training
has a positive effect on depressive symptoms.\r\n \r\n
\ \r\n What
is New:• A relevant proportion of adolescents with major
depressive disorder do not achieve their V̇O2max during a graded cardiopulmonary
exercise test.• Adolescents with major depressive disorder
have significantly lower cardiorespiratory fitness compared to sex- and age-related
control values.\r\n \r\n
\ "
author:
- first_name: Charlotte
full_name: Wenzel, Charlotte
last_name: Wenzel
- first_name: Bart Chateau
full_name: Bongers, Bart Chateau
last_name: Bongers
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Daniela
full_name: Reis, Daniela
last_name: Reis
- first_name: Franziska
full_name: Reinhard, Franziska
last_name: Reinhard
- first_name: Peter
full_name: Schmidt, Peter
last_name: Schmidt
- first_name: Stefan
full_name: Bernitzki, Stefan
last_name: Bernitzki
- first_name: Max
full_name: Oberste, Max
last_name: Oberste
- first_name: Heidrun Lioba
full_name: Wunram, Heidrun Lioba
last_name: Wunram
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
- first_name: Oliver
full_name: Fricke, Oliver
last_name: Fricke
citation:
ama: Wenzel C, Bongers BC, Schlagheck ML, et al. Validation of the maximal cardiopulmonary
exercise test in adolescents with major depressive disorder and comparison of
cardiorespiratory fitness with sex- and age-related control values. European
Journal of Pediatrics. 2023;183(1):379-388. doi:10.1007/s00431-023-05304-6
apa: Wenzel, C., Bongers, B. C., Schlagheck, M. L., Reis, D., Reinhard, F., Schmidt,
P., Bernitzki, S., Oberste, M., Wunram, H. L., Zimmer, P., & Fricke, O. (2023).
Validation of the maximal cardiopulmonary exercise test in adolescents with major
depressive disorder and comparison of cardiorespiratory fitness with sex- and
age-related control values. European Journal of Pediatrics, 183(1),
379–388. https://doi.org/10.1007/s00431-023-05304-6
bibtex: '@article{Wenzel_Bongers_Schlagheck_Reis_Reinhard_Schmidt_Bernitzki_Oberste_Wunram_Zimmer_et
al._2023, title={Validation of the maximal cardiopulmonary exercise test in adolescents
with major depressive disorder and comparison of cardiorespiratory fitness with
sex- and age-related control values}, volume={183}, DOI={10.1007/s00431-023-05304-6},
number={1}, journal={European Journal of Pediatrics}, publisher={Springer Science
and Business Media LLC}, author={Wenzel, Charlotte and Bongers, Bart Chateau and
Schlagheck, Marit Lea and Reis, Daniela and Reinhard, Franziska and Schmidt, Peter
and Bernitzki, Stefan and Oberste, Max and Wunram, Heidrun Lioba and Zimmer, Philipp
and et al.}, year={2023}, pages={379–388} }'
chicago: 'Wenzel, Charlotte, Bart Chateau Bongers, Marit Lea Schlagheck, Daniela
Reis, Franziska Reinhard, Peter Schmidt, Stefan Bernitzki, et al. “Validation
of the Maximal Cardiopulmonary Exercise Test in Adolescents with Major Depressive
Disorder and Comparison of Cardiorespiratory Fitness with Sex- and Age-Related
Control Values.” European Journal of Pediatrics 183, no. 1 (2023): 379–88.
https://doi.org/10.1007/s00431-023-05304-6.'
ieee: 'C. Wenzel et al., “Validation of the maximal cardiopulmonary exercise
test in adolescents with major depressive disorder and comparison of cardiorespiratory
fitness with sex- and age-related control values,” European Journal of Pediatrics,
vol. 183, no. 1, pp. 379–388, 2023, doi: 10.1007/s00431-023-05304-6.'
mla: Wenzel, Charlotte, et al. “Validation of the Maximal Cardiopulmonary Exercise
Test in Adolescents with Major Depressive Disorder and Comparison of Cardiorespiratory
Fitness with Sex- and Age-Related Control Values.” European Journal of Pediatrics,
vol. 183, no. 1, Springer Science and Business Media LLC, 2023, pp. 379–88, doi:10.1007/s00431-023-05304-6.
short: C. Wenzel, B.C. Bongers, M.L. Schlagheck, D. Reis, F. Reinhard, P. Schmidt,
S. Bernitzki, M. Oberste, H.L. Wunram, P. Zimmer, O. Fricke, European Journal
of Pediatrics 183 (2023) 379–388.
date_created: 2025-06-02T09:49:36Z
date_updated: 2025-06-02T09:52:44Z
doi: 10.1007/s00431-023-05304-6
extern: '1'
intvolume: ' 183'
issue: '1'
language:
- iso: eng
page: 379-388
publication: European Journal of Pediatrics
publication_identifier:
issn:
- 1432-1076
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Validation of the maximal cardiopulmonary exercise test in adolescents with
major depressive disorder and comparison of cardiorespiratory fitness with sex-
and age-related control values
type: journal_article
user_id: '117661'
volume: 183
year: '2023'
...
---
_id: '60096'
abstract:
- lang: eng
text: 'AbstractBackgroundResearchers
have increasingly differentiated trait‐like tendencies toward impulsivity occurring
during emotional states (emotion‐related impulsivity [ERI]) from impulsivity not
tied to emotion (non‐ERI). Relative to non‐ERI, ERI has shown robust correlations
with psychopathology and mild to moderate associations with physical health parameters
(e.g., physical activity, poor sleep quality, body mass index [BMI]). Therefore,
we first aimed to investigate the unique contributions of ERI and non‐ERI to psychopathology
symptoms while controlling for neuroticism. Second, we sought to explore the combined
associations of physical health parameters with several impulsivity forms.MethodsGerman‐speaking
adults (N = 350, 35.9 ± 14.6 years, 69.1% female, BMI:
24.0 ± 4.8 kg/m2, mostly students or employees) completed
measures of impulsivity, psychopathology symptoms, neuroticism, and physical health.
We gathered measures of two ERI forms: Feelings Trigger Action and Pervasive Influence
of Feelings. As a control comparison, we gathered a measure of non‐ERI, the Lack
of Follow‐Through scale. We conducted separate path models for Aims 1 and 2.ResultsFor
Aim 1, Pervasive Influence of Feelings showed strong links with internalizing
symptoms. Feelings Trigger Action and Lack of Follow‐Through showed small links
with alcohol use. For Aim 2, poor sleep quality was related to all three impulsivity
factors, while physical activity was only related to Pervasive Influence of Feelings
and Lack of Follow‐Through. BMI showed a curvilinear association with impulsivity.ConclusionsERI
is more directly relevant than non‐ERI for psychopathology symptoms, emphasizing
the need to differentiate between the two ERI types. The association of ERI and
non‐ERI with physical activity and poor sleep quality may serve as potential treatment
targets for impulsivity‐related problems.'
author:
- first_name: Florian
full_name: Javelle, Florian
last_name: Javelle
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Hannah C.
full_name: Broos, Hannah C.
last_name: Broos
- first_name: Kiara R.
full_name: Timpano, Kiara R.
last_name: Timpano
- first_name: Jutta
full_name: Joormann, Jutta
last_name: Joormann
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
- first_name: Sheri L.
full_name: Johnson, Sheri L.
last_name: Johnson
citation:
ama: 'Javelle F, Schlagheck ML, Broos HC, et al. On the impulsivity path: Examining
the unique and conjoint relations between emotion‐ and non‐emotion‐related impulsivity,
internalizing symptoms, alcohol use, and physical health parameters. Journal
of Clinical Psychology. 2023;80(2):339-354. doi:10.1002/jclp.23608'
apa: 'Javelle, F., Schlagheck, M. L., Broos, H. C., Timpano, K. R., Joormann, J.,
Zimmer, P., & Johnson, S. L. (2023). On the impulsivity path: Examining the
unique and conjoint relations between emotion‐ and non‐emotion‐related impulsivity,
internalizing symptoms, alcohol use, and physical health parameters. Journal
of Clinical Psychology, 80(2), 339–354. https://doi.org/10.1002/jclp.23608'
bibtex: '@article{Javelle_Schlagheck_Broos_Timpano_Joormann_Zimmer_Johnson_2023,
title={On the impulsivity path: Examining the unique and conjoint relations between
emotion‐ and non‐emotion‐related impulsivity, internalizing symptoms, alcohol
use, and physical health parameters}, volume={80}, DOI={10.1002/jclp.23608},
number={2}, journal={Journal of Clinical Psychology}, publisher={Wiley}, author={Javelle,
Florian and Schlagheck, Marit Lea and Broos, Hannah C. and Timpano, Kiara R. and
Joormann, Jutta and Zimmer, Philipp and Johnson, Sheri L.}, year={2023}, pages={339–354}
}'
chicago: 'Javelle, Florian, Marit Lea Schlagheck, Hannah C. Broos, Kiara R. Timpano,
Jutta Joormann, Philipp Zimmer, and Sheri L. Johnson. “On the Impulsivity Path:
Examining the Unique and Conjoint Relations between Emotion‐ and Non‐emotion‐related
Impulsivity, Internalizing Symptoms, Alcohol Use, and Physical Health Parameters.”
Journal of Clinical Psychology 80, no. 2 (2023): 339–54. https://doi.org/10.1002/jclp.23608.'
ieee: 'F. Javelle et al., “On the impulsivity path: Examining the unique
and conjoint relations between emotion‐ and non‐emotion‐related impulsivity, internalizing
symptoms, alcohol use, and physical health parameters,” Journal of Clinical
Psychology, vol. 80, no. 2, pp. 339–354, 2023, doi: 10.1002/jclp.23608.'
mla: 'Javelle, Florian, et al. “On the Impulsivity Path: Examining the Unique and
Conjoint Relations between Emotion‐ and Non‐emotion‐related Impulsivity, Internalizing
Symptoms, Alcohol Use, and Physical Health Parameters.” Journal of Clinical
Psychology, vol. 80, no. 2, Wiley, 2023, pp. 339–54, doi:10.1002/jclp.23608.'
short: F. Javelle, M.L. Schlagheck, H.C. Broos, K.R. Timpano, J. Joormann, P. Zimmer,
S.L. Johnson, Journal of Clinical Psychology 80 (2023) 339–354.
date_created: 2025-06-02T09:50:01Z
date_updated: 2025-06-02T09:52:02Z
doi: 10.1002/jclp.23608
extern: '1'
intvolume: ' 80'
issue: '2'
language:
- iso: eng
page: 339-354
publication: Journal of Clinical Psychology
publication_identifier:
issn:
- 0021-9762
- 1097-4679
publication_status: published
publisher: Wiley
status: public
title: 'On the impulsivity path: Examining the unique and conjoint relations between
emotion‐ and non‐emotion‐related impulsivity, internalizing symptoms, alcohol use,
and physical health parameters'
type: journal_article
user_id: '117661'
volume: 80
year: '2023'
...
---
_id: '60044'
abstract:
- lang: eng
text: AbstractExercise is described to provoke
enhancements of cardiorespiratory fitness in persons with Multiple Sclerosis (pwMS).
However, a high inter-individual variability in training responses has been observed.
This analysis investigates response heterogeneity in cardiorespiratory fitness
following high intensity interval (HIIT) and moderate continuous training (MCT)
and analyzes potential predictors of cardiorespiratory training effects in pwMS.
131 pwMS performed HIIT or MCT 3–5x/ week on a cycle ergometer for three weeks.
Individual responses were classified. Finally, a multiple linear regression was
conducted to examine potential associations between changes of absolute peak oxygen
consumption (absolute ∆V̇O2peak/kg), training modality and participant’s characteristics.
Results show a time and interaction effect for ∆V̇O2peak/kg. Absolute changes
of cardiorespiratory responses were larger and the non-response proportions smaller
in HIIT vs. MCT. The model accounting for 8.6% of the variance of ∆V̇O2peak/kg
suggests that HIIT, younger age and lower baseline fitness predict a higher absolute
∆V̇O2peak/kg following an exercise intervention. Thus, this work implements a
novel approach that investigates potential determinants of cardiorespiratory response
heterogeneity within a clinical setting and analyzes a remarkable bigger sample.
Further predictors need to be identified to increase the knowledge about response
heterogeneity, thereby supporting the development of individualized training recommendations
for pwMS.
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Anika
full_name: Wucherer, Anika
last_name: Wucherer
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Sebastian
full_name: Proschinger, Sebastian
last_name: Proschinger
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Jan
full_name: Kool, Jan
last_name: Kool
- first_name: Roman
full_name: Gonzenbach, Roman
last_name: Gonzenbach
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: 'Schlagheck ML, Wucherer A, Rademacher A, et al. VO2peak Response Heterogeneity
in Persons with Multiple Sclerosis: To HIIT or Not to HIIT? International Journal
of Sports Medicine. 2021;42(14):1319-1328. doi:10.1055/a-1481-8639'
apa: 'Schlagheck, M. L., Wucherer, A., Rademacher, A., Joisten, N., Proschinger,
S., Walzik, D., Bloch, W., Kool, J., Gonzenbach, R., Bansi, J., & Zimmer,
P. (2021). VO2peak Response Heterogeneity in Persons with Multiple Sclerosis:
To HIIT or Not to HIIT? International Journal of Sports Medicine, 42(14),
1319–1328. https://doi.org/10.1055/a-1481-8639'
bibtex: '@article{Schlagheck_Wucherer_Rademacher_Joisten_Proschinger_Walzik_Bloch_Kool_Gonzenbach_Bansi_et
al._2021, title={VO2peak Response Heterogeneity in Persons with Multiple Sclerosis:
To HIIT or Not to HIIT?}, volume={42}, DOI={10.1055/a-1481-8639},
number={14}, journal={International Journal of Sports Medicine}, publisher={Georg
Thieme Verlag KG}, author={Schlagheck, Marit Lea and Wucherer, Anika and Rademacher,
Annette and Joisten, Niklas and Proschinger, Sebastian and Walzik, David and Bloch,
Wilhelm and Kool, Jan and Gonzenbach, Roman and Bansi, Jens and et al.}, year={2021},
pages={1319–1328} }'
chicago: 'Schlagheck, Marit Lea, Anika Wucherer, Annette Rademacher, Niklas Joisten,
Sebastian Proschinger, David Walzik, Wilhelm Bloch, et al. “VO2peak Response Heterogeneity
in Persons with Multiple Sclerosis: To HIIT or Not to HIIT?” International
Journal of Sports Medicine 42, no. 14 (2021): 1319–28. https://doi.org/10.1055/a-1481-8639.'
ieee: 'M. L. Schlagheck et al., “VO2peak Response Heterogeneity in Persons
with Multiple Sclerosis: To HIIT or Not to HIIT?,” International Journal of
Sports Medicine, vol. 42, no. 14, pp. 1319–1328, 2021, doi: 10.1055/a-1481-8639.'
mla: 'Schlagheck, Marit Lea, et al. “VO2peak Response Heterogeneity in Persons with
Multiple Sclerosis: To HIIT or Not to HIIT?” International Journal of Sports
Medicine, vol. 42, no. 14, Georg Thieme Verlag KG, 2021, pp. 1319–28, doi:10.1055/a-1481-8639.'
short: M.L. Schlagheck, A. Wucherer, A. Rademacher, N. Joisten, S. Proschinger,
D. Walzik, W. Bloch, J. Kool, R. Gonzenbach, J. Bansi, P. Zimmer, International
Journal of Sports Medicine 42 (2021) 1319–1328.
date_created: 2025-05-27T07:54:18Z
date_updated: 2025-06-02T09:33:48Z
doi: 10.1055/a-1481-8639
extern: '1'
intvolume: ' 42'
issue: '14'
language:
- iso: eng
page: 1319-1328
publication: International Journal of Sports Medicine
publication_identifier:
issn:
- 0172-4622
- 1439-3964
publication_status: published
publisher: Georg Thieme Verlag KG
status: public
title: 'VO2peak Response Heterogeneity in Persons with Multiple Sclerosis: To HIIT
or Not to HIIT?'
type: journal_article
user_id: '117661'
volume: 42
year: '2021'
...
---
_id: '60043'
article_number: '102905'
author:
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Sebastian
full_name: Proschinger, Sebastian
last_name: Proschinger
- first_name: Jonas
full_name: Hebchen, Jonas
last_name: Hebchen
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Roman
full_name: Gonzenbach, Roman
last_name: Gonzenbach
- first_name: Jan
full_name: Kool, Jan
last_name: Kool
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Rademacher A, Joisten N, Proschinger S, et al. Do baseline cognitive status,
participant specific characteristics and EDSS impact changes of cognitive performance
following aerobic exercise intervention in multiple sclerosis? Multiple Sclerosis
and Related Disorders. 2021;51. doi:10.1016/j.msard.2021.102905
apa: Rademacher, A., Joisten, N., Proschinger, S., Hebchen, J., Schlagheck, M. L.,
Bloch, W., Gonzenbach, R., Kool, J., Bansi, J., & Zimmer, P. (2021). Do baseline
cognitive status, participant specific characteristics and EDSS impact changes
of cognitive performance following aerobic exercise intervention in multiple sclerosis?
Multiple Sclerosis and Related Disorders, 51, Article 102905. https://doi.org/10.1016/j.msard.2021.102905
bibtex: '@article{Rademacher_Joisten_Proschinger_Hebchen_Schlagheck_Bloch_Gonzenbach_Kool_Bansi_Zimmer_2021,
title={Do baseline cognitive status, participant specific characteristics and
EDSS impact changes of cognitive performance following aerobic exercise intervention
in multiple sclerosis?}, volume={51}, DOI={10.1016/j.msard.2021.102905},
number={102905}, journal={Multiple Sclerosis and Related Disorders}, publisher={Elsevier
BV}, author={Rademacher, Annette and Joisten, Niklas and Proschinger, Sebastian
and Hebchen, Jonas and Schlagheck, Marit Lea and Bloch, Wilhelm and Gonzenbach,
Roman and Kool, Jan and Bansi, Jens and Zimmer, Philipp}, year={2021} }'
chicago: Rademacher, Annette, Niklas Joisten, Sebastian Proschinger, Jonas Hebchen,
Marit Lea Schlagheck, Wilhelm Bloch, Roman Gonzenbach, Jan Kool, Jens Bansi, and
Philipp Zimmer. “Do Baseline Cognitive Status, Participant Specific Characteristics
and EDSS Impact Changes of Cognitive Performance Following Aerobic Exercise Intervention
in Multiple Sclerosis?” Multiple Sclerosis and Related Disorders 51 (2021).
https://doi.org/10.1016/j.msard.2021.102905.
ieee: 'A. Rademacher et al., “Do baseline cognitive status, participant specific
characteristics and EDSS impact changes of cognitive performance following aerobic
exercise intervention in multiple sclerosis?,” Multiple Sclerosis and Related
Disorders, vol. 51, Art. no. 102905, 2021, doi: 10.1016/j.msard.2021.102905.'
mla: Rademacher, Annette, et al. “Do Baseline Cognitive Status, Participant Specific
Characteristics and EDSS Impact Changes of Cognitive Performance Following Aerobic
Exercise Intervention in Multiple Sclerosis?” Multiple Sclerosis and Related
Disorders, vol. 51, 102905, Elsevier BV, 2021, doi:10.1016/j.msard.2021.102905.
short: A. Rademacher, N. Joisten, S. Proschinger, J. Hebchen, M.L. Schlagheck, W.
Bloch, R. Gonzenbach, J. Kool, J. Bansi, P. Zimmer, Multiple Sclerosis and Related
Disorders 51 (2021).
date_created: 2025-05-27T07:54:02Z
date_updated: 2025-06-02T09:34:33Z
doi: 10.1016/j.msard.2021.102905
extern: '1'
intvolume: ' 51'
language:
- iso: eng
publication: Multiple Sclerosis and Related Disorders
publication_identifier:
issn:
- 2211-0348
publication_status: published
publisher: Elsevier BV
status: public
title: Do baseline cognitive status, participant specific characteristics and EDSS
impact changes of cognitive performance following aerobic exercise intervention
in multiple sclerosis?
type: journal_article
user_id: '117661'
volume: 51
year: '2021'
...
---
_id: '60045'
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Florian
full_name: Wolf, Florian
last_name: Wolf
- first_name: Sarah E.
full_name: Neil-Sztramko, Sarah E.
last_name: Neil-Sztramko
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: 'Schlagheck ML, Joisten N, Walzik D, et al. Systematic Review of Exercise Studies
in Persons with Multiple Sclerosis: Exploring the Quality of Interventions According
to the Principles of Exercise Training. Neurology and Therapy. 2021;10(2):585-607.
doi:10.1007/s40120-021-00274-z'
apa: 'Schlagheck, M. L., Joisten, N., Walzik, D., Wolf, F., Neil-Sztramko, S. E.,
Bansi, J., Rademacher, A., & Zimmer, P. (2021). Systematic Review of Exercise
Studies in Persons with Multiple Sclerosis: Exploring the Quality of Interventions
According to the Principles of Exercise Training. Neurology and Therapy,
10(2), 585–607. https://doi.org/10.1007/s40120-021-00274-z'
bibtex: '@article{Schlagheck_Joisten_Walzik_Wolf_Neil-Sztramko_Bansi_Rademacher_Zimmer_2021,
title={Systematic Review of Exercise Studies in Persons with Multiple Sclerosis:
Exploring the Quality of Interventions According to the Principles of Exercise
Training}, volume={10}, DOI={10.1007/s40120-021-00274-z},
number={2}, journal={Neurology and Therapy}, publisher={Springer Science and Business
Media LLC}, author={Schlagheck, Marit Lea and Joisten, Niklas and Walzik, David
and Wolf, Florian and Neil-Sztramko, Sarah E. and Bansi, Jens and Rademacher,
Annette and Zimmer, Philipp}, year={2021}, pages={585–607} }'
chicago: 'Schlagheck, Marit Lea, Niklas Joisten, David Walzik, Florian Wolf, Sarah
E. Neil-Sztramko, Jens Bansi, Annette Rademacher, and Philipp Zimmer. “Systematic
Review of Exercise Studies in Persons with Multiple Sclerosis: Exploring the Quality
of Interventions According to the Principles of Exercise Training.” Neurology
and Therapy 10, no. 2 (2021): 585–607. https://doi.org/10.1007/s40120-021-00274-z.'
ieee: 'M. L. Schlagheck et al., “Systematic Review of Exercise Studies in
Persons with Multiple Sclerosis: Exploring the Quality of Interventions According
to the Principles of Exercise Training,” Neurology and Therapy, vol. 10,
no. 2, pp. 585–607, 2021, doi: 10.1007/s40120-021-00274-z.'
mla: 'Schlagheck, Marit Lea, et al. “Systematic Review of Exercise Studies in Persons
with Multiple Sclerosis: Exploring the Quality of Interventions According to the
Principles of Exercise Training.” Neurology and Therapy, vol. 10, no. 2,
Springer Science and Business Media LLC, 2021, pp. 585–607, doi:10.1007/s40120-021-00274-z.'
short: M.L. Schlagheck, N. Joisten, D. Walzik, F. Wolf, S.E. Neil-Sztramko, J. Bansi,
A. Rademacher, P. Zimmer, Neurology and Therapy 10 (2021) 585–607.
date_created: 2025-05-27T07:54:31Z
date_updated: 2025-06-02T09:34:58Z
doi: 10.1007/s40120-021-00274-z
extern: '1'
intvolume: ' 10'
issue: '2'
language:
- iso: eng
page: 585-607
publication: Neurology and Therapy
publication_identifier:
issn:
- 2193-8253
- 2193-6536
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: 'Systematic Review of Exercise Studies in Persons with Multiple Sclerosis:
Exploring the Quality of Interventions According to the Principles of Exercise Training'
type: journal_article
user_id: '117661'
volume: 10
year: '2021'
...
---
_id: '60090'
article_number: '103476'
author:
- first_name: Florian
full_name: Wolf, Florian
last_name: Wolf
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Sebastian
full_name: Proschinger, Sebastian
last_name: Proschinger
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Roman
full_name: Gonzenbach, Roman
last_name: Gonzenbach
- first_name: Jan
full_name: Kool, Jan
last_name: Kool
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Wolf F, Rademacher A, Joisten N, et al. The aerobic capacity – fatigue relationship
in persons with Multiple Sclerosis is not reproducible in a pooled analysis of
two randomized controlled trials. Multiple Sclerosis and Related Disorders.
2021;58. doi:10.1016/j.msard.2021.103476
apa: Wolf, F., Rademacher, A., Joisten, N., Proschinger, S., Schlagheck, M. L.,
Bloch, W., Gonzenbach, R., Kool, J., Bansi, J., & Zimmer, P. (2021). The aerobic
capacity – fatigue relationship in persons with Multiple Sclerosis is not reproducible
in a pooled analysis of two randomized controlled trials. Multiple Sclerosis
and Related Disorders, 58, Article 103476. https://doi.org/10.1016/j.msard.2021.103476
bibtex: '@article{Wolf_Rademacher_Joisten_Proschinger_Schlagheck_Bloch_Gonzenbach_Kool_Bansi_Zimmer_2021,
title={The aerobic capacity – fatigue relationship in persons with Multiple Sclerosis
is not reproducible in a pooled analysis of two randomized controlled trials},
volume={58}, DOI={10.1016/j.msard.2021.103476},
number={103476}, journal={Multiple Sclerosis and Related Disorders}, publisher={Elsevier
BV}, author={Wolf, Florian and Rademacher, Annette and Joisten, Niklas and Proschinger,
Sebastian and Schlagheck, Marit Lea and Bloch, Wilhelm and Gonzenbach, Roman and
Kool, Jan and Bansi, Jens and Zimmer, Philipp}, year={2021} }'
chicago: Wolf, Florian, Annette Rademacher, Niklas Joisten, Sebastian Proschinger,
Marit Lea Schlagheck, Wilhelm Bloch, Roman Gonzenbach, Jan Kool, Jens Bansi, and
Philipp Zimmer. “The Aerobic Capacity – Fatigue Relationship in Persons with Multiple
Sclerosis Is Not Reproducible in a Pooled Analysis of Two Randomized Controlled
Trials.” Multiple Sclerosis and Related Disorders 58 (2021). https://doi.org/10.1016/j.msard.2021.103476.
ieee: 'F. Wolf et al., “The aerobic capacity – fatigue relationship in persons
with Multiple Sclerosis is not reproducible in a pooled analysis of two randomized
controlled trials,” Multiple Sclerosis and Related Disorders, vol. 58,
Art. no. 103476, 2021, doi: 10.1016/j.msard.2021.103476.'
mla: Wolf, Florian, et al. “The Aerobic Capacity – Fatigue Relationship in Persons
with Multiple Sclerosis Is Not Reproducible in a Pooled Analysis of Two Randomized
Controlled Trials.” Multiple Sclerosis and Related Disorders, vol. 58,
103476, Elsevier BV, 2021, doi:10.1016/j.msard.2021.103476.
short: F. Wolf, A. Rademacher, N. Joisten, S. Proschinger, M.L. Schlagheck, W. Bloch,
R. Gonzenbach, J. Kool, J. Bansi, P. Zimmer, Multiple Sclerosis and Related Disorders
58 (2021).
date_created: 2025-06-02T09:41:32Z
date_updated: 2025-06-02T09:45:25Z
doi: 10.1016/j.msard.2021.103476
extern: '1'
intvolume: ' 58'
language:
- iso: eng
publication: Multiple Sclerosis and Related Disorders
publication_identifier:
issn:
- 2211-0348
publication_status: published
publisher: Elsevier BV
status: public
title: The aerobic capacity – fatigue relationship in persons with Multiple Sclerosis
is not reproducible in a pooled analysis of two randomized controlled trials
type: journal_article
user_id: '117661'
volume: 58
year: '2021'
...
---
_id: '60042'
abstract:
- lang: eng
text: AbstractObjectivesExercise‐induced
cellular mobilization might play a role in treatment and prevention of several
diseases. However, little is known about the impact of different exercise modalities
on immune cell mobilization and clinical cellular inflammation markers. Therefore,
the present study aimed to investigate differences between acute endurance exercise
(EE) and resistance exercise (RE) on cellular immune alterations.MethodsTwenty‐four
healthy men conducted an acute EE (cycling at 60% of peak power output) and RE
(five exercise machines at 70% of the one‐repetition maximum) session lasting
50 minutes in randomized order. Blood samples were collected before, after and
one hour after exercise cessation. Outcomes included counts and proportions of
leukocytes, neutrophils (NEUT), lymphocytes (LYM), LYM subsets, CD4/CD8 ratio,
and the clinical cellular inflammation markers NEUT/LYM ratio (NLR), platelets/LYM
ratio (PLR), and systemic immune inflammation index (SII).ResultsAlterations
in all outcomes were revealed except for CD8+T cells, CD4/CD8
ratio, NLR, and PLR. EE induced a stronger cellular immune response and provoked
alterations in more immune cell populations than RE. SII was altered only after
EE.ConclusionAn
acute EE session causes a stronger mobilization of immune cells than RE. Additionally,
SII represents an integrative marker to depict immunological alterations.
author:
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Christina
full_name: Koliamitra, Christina
last_name: Koliamitra
- first_name: Luca
full_name: Hardt, Luca
last_name: Hardt
- first_name: Alan J.
full_name: Metcalfe, Alan J.
last_name: Metcalfe
- first_name: Patrick
full_name: Wahl, Patrick
last_name: Wahl
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Alexander
full_name: Schenk, Alexander
last_name: Schenk
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: 'Schlagheck ML, Walzik D, Joisten N, et al. Cellular immune response to acute
exercise: Comparison of endurance and resistance exercise. European Journal
of Haematology. 2020;105(1):75-84. doi:10.1111/ejh.13412'
apa: 'Schlagheck, M. L., Walzik, D., Joisten, N., Koliamitra, C., Hardt, L., Metcalfe,
A. J., Wahl, P., Bloch, W., Schenk, A., & Zimmer, P. (2020). Cellular immune
response to acute exercise: Comparison of endurance and resistance exercise. European
Journal of Haematology, 105(1), 75–84. https://doi.org/10.1111/ejh.13412'
bibtex: '@article{Schlagheck_Walzik_Joisten_Koliamitra_Hardt_Metcalfe_Wahl_Bloch_Schenk_Zimmer_2020,
title={Cellular immune response to acute exercise: Comparison of endurance and
resistance exercise}, volume={105}, DOI={10.1111/ejh.13412},
number={1}, journal={European Journal of Haematology}, publisher={Wiley}, author={Schlagheck,
Marit Lea and Walzik, David and Joisten, Niklas and Koliamitra, Christina and
Hardt, Luca and Metcalfe, Alan J. and Wahl, Patrick and Bloch, Wilhelm and Schenk,
Alexander and Zimmer, Philipp}, year={2020}, pages={75–84} }'
chicago: 'Schlagheck, Marit Lea, David Walzik, Niklas Joisten, Christina Koliamitra,
Luca Hardt, Alan J. Metcalfe, Patrick Wahl, Wilhelm Bloch, Alexander Schenk, and
Philipp Zimmer. “Cellular Immune Response to Acute Exercise: Comparison of Endurance
and Resistance Exercise.” European Journal of Haematology 105, no. 1 (2020):
75–84. https://doi.org/10.1111/ejh.13412.'
ieee: 'M. L. Schlagheck et al., “Cellular immune response to acute exercise:
Comparison of endurance and resistance exercise,” European Journal of Haematology,
vol. 105, no. 1, pp. 75–84, 2020, doi: 10.1111/ejh.13412.'
mla: 'Schlagheck, Marit Lea, et al. “Cellular Immune Response to Acute Exercise:
Comparison of Endurance and Resistance Exercise.” European Journal of Haematology,
vol. 105, no. 1, Wiley, 2020, pp. 75–84, doi:10.1111/ejh.13412.'
short: M.L. Schlagheck, D. Walzik, N. Joisten, C. Koliamitra, L. Hardt, A.J. Metcalfe,
P. Wahl, W. Bloch, A. Schenk, P. Zimmer, European Journal of Haematology 105 (2020)
75–84.
date_created: 2025-05-27T07:42:01Z
date_updated: 2025-06-02T09:34:46Z
doi: 10.1111/ejh.13412
extern: '1'
intvolume: ' 105'
issue: '1'
language:
- iso: eng
page: 75-84
publication: European Journal of Haematology
publication_identifier:
issn:
- 0902-4441
- 1600-0609
publication_status: published
publisher: Wiley
status: public
title: 'Cellular immune response to acute exercise: Comparison of endurance and resistance
exercise'
type: journal_article
user_id: '117661'
volume: 105
year: '2020'
...
---
_id: '60088'
article_number: '314'
author:
- first_name: Sebastian
full_name: Proschinger, Sebastian
last_name: Proschinger
- first_name: Niklas
full_name: Joisten, Niklas
last_name: Joisten
- first_name: Annette
full_name: Rademacher, Annette
last_name: Rademacher
- first_name: Marit Lea
full_name: Schlagheck, Marit Lea
id: '117661'
last_name: Schlagheck
orcid: '0000-0002-8913-6080 '
- first_name: David
full_name: Walzik, David
last_name: Walzik
- first_name: Alan J.
full_name: Metcalfe, Alan J.
last_name: Metcalfe
- first_name: Max
full_name: Oberste, Max
last_name: Oberste
- first_name: Clemens
full_name: Warnke, Clemens
last_name: Warnke
- first_name: Wilhelm
full_name: Bloch, Wilhelm
last_name: Bloch
- first_name: Alexander
full_name: Schenk, Alexander
last_name: Schenk
- first_name: Jens
full_name: Bansi, Jens
last_name: Bansi
- first_name: Philipp
full_name: Zimmer, Philipp
last_name: Zimmer
citation:
ama: Proschinger S, Joisten N, Rademacher A, et al. Influence of combined functional
resistance and endurance exercise over 12 weeks on matrix metalloproteinase-2
serum concentration in persons with relapsing-remitting multiple sclerosis – a
community-based randomized controlled trial. BMC Neurology. 2019;19(1).
doi:10.1186/s12883-019-1544-7
apa: Proschinger, S., Joisten, N., Rademacher, A., Schlagheck, M. L., Walzik, D.,
Metcalfe, A. J., Oberste, M., Warnke, C., Bloch, W., Schenk, A., Bansi, J., &
Zimmer, P. (2019). Influence of combined functional resistance and endurance exercise
over 12 weeks on matrix metalloproteinase-2 serum concentration in persons with
relapsing-remitting multiple sclerosis – a community-based randomized controlled
trial. BMC Neurology, 19(1), Article 314. https://doi.org/10.1186/s12883-019-1544-7
bibtex: '@article{Proschinger_Joisten_Rademacher_Schlagheck_Walzik_Metcalfe_Oberste_Warnke_Bloch_Schenk_et
al._2019, title={Influence of combined functional resistance and endurance exercise
over 12 weeks on matrix metalloproteinase-2 serum concentration in persons with
relapsing-remitting multiple sclerosis – a community-based randomized controlled
trial}, volume={19}, DOI={10.1186/s12883-019-1544-7},
number={1314}, journal={BMC Neurology}, publisher={Springer Science and Business
Media LLC}, author={Proschinger, Sebastian and Joisten, Niklas and Rademacher,
Annette and Schlagheck, Marit Lea and Walzik, David and Metcalfe, Alan J. and
Oberste, Max and Warnke, Clemens and Bloch, Wilhelm and Schenk, Alexander and
et al.}, year={2019} }'
chicago: Proschinger, Sebastian, Niklas Joisten, Annette Rademacher, Marit Lea Schlagheck,
David Walzik, Alan J. Metcalfe, Max Oberste, et al. “Influence of Combined Functional
Resistance and Endurance Exercise over 12 Weeks on Matrix Metalloproteinase-2
Serum Concentration in Persons with Relapsing-Remitting Multiple Sclerosis – a
Community-Based Randomized Controlled Trial.” BMC Neurology 19, no. 1 (2019).
https://doi.org/10.1186/s12883-019-1544-7.
ieee: 'S. Proschinger et al., “Influence of combined functional resistance
and endurance exercise over 12 weeks on matrix metalloproteinase-2 serum concentration
in persons with relapsing-remitting multiple sclerosis – a community-based randomized
controlled trial,” BMC Neurology, vol. 19, no. 1, Art. no. 314, 2019, doi:
10.1186/s12883-019-1544-7.'
mla: Proschinger, Sebastian, et al. “Influence of Combined Functional Resistance
and Endurance Exercise over 12 Weeks on Matrix Metalloproteinase-2 Serum Concentration
in Persons with Relapsing-Remitting Multiple Sclerosis – a Community-Based Randomized
Controlled Trial.” BMC Neurology, vol. 19, no. 1, 314, Springer Science
and Business Media LLC, 2019, doi:10.1186/s12883-019-1544-7.
short: S. Proschinger, N. Joisten, A. Rademacher, M.L. Schlagheck, D. Walzik, A.J.
Metcalfe, M. Oberste, C. Warnke, W. Bloch, A. Schenk, J. Bansi, P. Zimmer, BMC
Neurology 19 (2019).
date_created: 2025-06-02T09:39:20Z
date_updated: 2025-06-02T09:47:30Z
doi: 10.1186/s12883-019-1544-7
extern: '1'
intvolume: ' 19'
issue: '1'
language:
- iso: eng
publication: BMC Neurology
publication_identifier:
issn:
- 1471-2377
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Influence of combined functional resistance and endurance exercise over 12 weeks
on matrix metalloproteinase-2 serum concentration in persons with relapsing-remitting
multiple sclerosis – a community-based randomized controlled trial
type: journal_article
user_id: '117661'
volume: 19
year: '2019'
...