@article{62936,
  author       = {{Ruhm, Lukas and Neßlinger, Vanessa and Becker, Roman and Meschut, Gerson and Grundmeier, Guido}},
  issn         = {{0143-7496}},
  journal      = {{International Journal of Adhesion and Adhesives}},
  publisher    = {{Elsevier BV}},
  title        = {{{A contribution to the mechanistic understanding of the improvement of the delamination resistance of adhesives on steel by grit-blasting}}},
  doi          = {{10.1016/j.ijadhadh.2025.104147}},
  volume       = {{143}},
  year         = {{2025}},
}

@article{62938,
  author       = {{Müller, Hendrik and Cetin, Ali and Dahlmann, Rainer and de los Arcos, Teresa and Grundmeier, Guido}},
  issn         = {{0257-8972}},
  journal      = {{Surface and Coatings Technology}},
  publisher    = {{Elsevier BV}},
  title        = {{{Interface chemistry and adhesion of thin bilayer Si-organic PECVD barrier films on post-consumer recycled polypropylene}}},
  doi          = {{10.1016/j.surfcoat.2025.132392}},
  volume       = {{512}},
  year         = {{2025}},
}

@article{62939,
  author       = {{Su, Jiangling and Muhle, Marius and Nembot, Nelly and Prüßner, Tim and Xie, Xiaofan and Wittstock, Gunther and Grundmeier, Guido}},
  issn         = {{0013-4686}},
  journal      = {{Electrochimica Acta}},
  publisher    = {{Elsevier BV}},
  title        = {{{Spontaneous grafting of nitrobenzenediazonium salt on plasma-modified copper substrates}}},
  doi          = {{10.1016/j.electacta.2025.147810}},
  volume       = {{546}},
  year         = {{2025}},
}

@article{51121,
  abstract     = {{<jats:p>DNA origami nanostructures are a powerful tool in biomedicine and can be used to combat drug‐resistant bacterial infections. However, the effect of unmodified DNA origami nanostructures on bacteria is yet to be elucidated. With the aim to obtain a better understanding of this phenomenon, the effect of three DNA origami shapes, i.e., DNA origami triangles, six‐helix bundles (6HBs), and 24‐helix bundles (24HBs), on the growth of Gram‐negative Escherichia coli and Gram‐positive Bacillus subtilis is investigated. These results reveal that while triangles and 24HBs can be used as a source of nutrients by E. coli and thereby promote population growth, their effect is much smaller than that of genomic single‐ and double‐stranded DNA. However, no effect on E. coli population growth is observed for the 6HBs. On the other hand, B. subtilis does not show any significant changes in population growth when cultured with the different DNA origami shapes or genomic DNA. The detailed effect of DNA origami nanostructures on bacterial growth thus depends on the competence signals and uptake mechanism of each bacterial species, as well as the DNA origami shape. This should be considered in the development of antimicrobial DNA origami nanostructures.</jats:p>}},
  author       = {{Garcia-Diosa, Jaime Andres and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{1439-4227}},
  journal      = {{ChemBioChem}},
  keywords     = {{Organic Chemistry, Molecular Biology, Molecular Medicine, Biochemistry}},
  publisher    = {{Wiley}},
  title        = {{{Effect of DNA Origami Nanostructures on Bacterial Growth}}},
  doi          = {{10.1002/cbic.202400091}},
  year         = {{2024}},
}

@article{53621,
  abstract     = {{<jats:p>The coupling of structural transitions to heat capacity changes leads to destabilization of macromolecules at both, elevated and lowered temperatures. DNA origami not only exhibit this property but also provide...</jats:p>}},
  author       = {{Dornbusch, Daniel and Hanke, Marcel and Tomm, Emilia and Kielar, Charlotte and Grundmeier, Guido and Keller, Adrian and Fahmy, Karim}},
  issn         = {{1359-7345}},
  journal      = {{Chemical Communications}},
  keywords     = {{Materials Chemistry, Metals and Alloys, Surfaces, Coatings and Films, General Chemistry, Ceramics and Composites, Electronic, Optical and Magnetic Materials, Catalysis}},
  publisher    = {{Royal Society of Chemistry (RSC)}},
  title        = {{{Cold denaturation of DNA origami nanostructures}}},
  doi          = {{10.1039/d3cc05985e}},
  year         = {{2024}},
}

@article{54644,
  abstract     = {{<jats:p>DNA origami nanostructures (DONs) are able to scavenge reactive oxygen species (ROS) and their scavenging efficiency toward ROS radicals was shown to be comparable to that of genomic DNA. Herein, we demonstrate that DONs are highly efficient singlet oxygen quenchers outperforming double‐stranded (ds) DNA by several orders of magnitude. To this end, a ROS mixture rich in singlet oxygen is generated by light irradiation of the photosensitizer methylene blue and its cytotoxic effect on Escherichia coli cells is quantified in the presence and absence of DONs. DONs are found to be vastly superior to dsDNA in protecting the bacteria from ROS‐induced damage and even surpass established ROS scavengers. At a concentration of 15 nM, DONs are about 50 000 times more efficient ROS scavengers than dsDNA at an equivalent concentration. This is attributed to the dominant role of singlet oxygen, which has a long diffusion length and reacts specifically with guanine. The dense packing of the available guanines into the small volume of the DON increases the overall quenching probability compared to a linear dsDNA with the same number of base pairs. DONs thus have great potential to alleviate oxidative stress caused by singlet oxygen in diverse therapeutic settings.</jats:p>}},
  author       = {{Garcia-Diosa, Jaime Andres and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{0947-6539}},
  journal      = {{Chemistry – A European Journal}},
  publisher    = {{Wiley}},
  title        = {{{Highly Efficient Quenching of Singlet Oxygen by DNA Origami Nanostructures}}},
  doi          = {{10.1002/chem.202402057}},
  year         = {{2024}},
}

@article{55310,
  abstract     = {{<jats:p>DNA origami nanostructures are promising carries for drug delivery applications. However, their limited stability under relevant conditions often presents a challenge. Herein, the structural stability of DNA origami nanostructures is investigated in a setting compatible with their application in photodynamic therapy (PDT). To this end, DNA origami triangles and six‐helix bundles (6HBs) are loaded with the clinically tested photosensitizer methylene blue, which upon irradiation with red light generates reactive oxygen species (ROS) that attack the DNA origami nanostructures. ROS‐induced structural damage is observed to depend on the ionic composition of the surrounding medium and becomes more severe at low ionic strength. Mg<jats:sup>2+</jats:sup> ions can efficiently protect the DNA origami nanostructures from ROS‐induced damage and may even heal some of the damage obtained under Mg<jats:sup>2+</jats:sup>‐free conditions when added after irradiation. Finally, the employed DNA origami 6HBs are more resistant toward ROS‐induced structural damage than the triangles, which is attributed to their markedly different mechanical properties. These results thus provide some fundamental insights into the stabilizing role of DNA origami superstructure that may guide the selection or design of DNA origami nanocarriers with optimized stability for their application in PDT.</jats:p>}},
  author       = {{Rabbe, Lukas and Garcia‐Diosa, Jaime Andres and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2688-4062}},
  journal      = {{Small Structures}},
  publisher    = {{Wiley}},
  title        = {{{Ion‐Dependent Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated Reactive Oxygen Species}}},
  doi          = {{10.1002/sstr.202400094}},
  year         = {{2024}},
}

@article{58612,
  author       = {{Luis-Sunga, Maximina and González-Orive, Alejandro and Calderón, Juan Carlos and Gamba, Ilaria and Ródenas, Airán and de los Arcos de Pedro, Maria Teresa and Hernández-Creus, Alberto and Grundmeier, Guido and Pastor, Elena and García, Gonzalo}},
  issn         = {{2574-0970}},
  journal      = {{ACS Applied Nano Materials}},
  title        = {{{Nickel-Induced Reduced Graphene Oxide Nanoribbon Formation on Highly Ordered Pyrolytic Graphite for Electronic and Magnetic Applications}}},
  doi          = {{10.1021/acsanm.3c05949}},
  year         = {{2024}},
}

@article{58611,
  abstract     = {{AFM-IR investigation of thin PECVD SiOx films on a polypropylene substrate in the surface-sensitive mode}},
  author       = {{Müller, Hendrik and Stadler, Hartmut and de los Arcos de Pedro, Maria Teresa and Keller, Adrian and Grundmeier, Guido}},
  issn         = {{2190-4286}},
  journal      = {{Beilstein Journal of Nanotechnology}},
  number       = {{1}},
  pages        = {{603–611}},
  title        = {{{AFM-IR investigation of thin PECVD SiO x films on a polypropylene substrate in the surface-sensitive mode}}},
  doi          = {{10.3762/bjnano.15.51}},
  volume       = {{15}},
  year         = {{2024}},
}

@article{62236,
  abstract     = {{<jats:title>Abstract</jats:title><jats:p>Due to its excellent biocompatibility, pure iron is a very promising implant material, but often features corrosion rates that are too low. Using additive manufacturing and modified powders the microstructure and, thus, the material properties, e.g., the corrosion properties, can be tailored for specific applications. Within the scope of this study, pure iron powder was modified with different amounts of CeO<jats:sub>2</jats:sub> or Fe<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> nanoparticles and subsequently processed by Electron Beam Powder Bed Fusion (PBF-EB/M). The corrosion-fatigue behavior of CeO<jats:sub>2</jats:sub> and Fe<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> modified iron was investigated using rotation bending tests under the influence of simulated body fluid (m-SBF). While the modification using Fe<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> showed reduced fatigue and corrosion-fatigue strengths, it could be demonstrated that the modification with CeO<jats:sub>2</jats:sub> is characterized by improved fatigue properties. The superior fatigue properties in air are attributed to the positive impact of dispersion strengthening. Additionally, an increased degradation rate compared to pure iron could be observed, eventually promoting an earlier failure of the specimens in the corrosion fatigue tests.</jats:p>}},
  author       = {{Wackenrohr, Steffen and Torrent, Christof Johannes Jaime and Herbst, Sebastian and Nürnberger, Florian and Krooss, Philipp and Frenck, Johanna-Maria and Ebbert, Christoph and Voigt, Markus and Grundmeier, Guido and Niendorf, Thomas and Maier, Hans Jürgen}},
  issn         = {{2397-2106}},
  journal      = {{npj Materials Degradation}},
  number       = {{1}},
  publisher    = {{Springer Science and Business Media LLC}},
  title        = {{{Corrosion fatigue behavior of nanoparticle modified iron processed by electron powder bed fusion}}},
  doi          = {{10.1038/s41529-024-00470-w}},
  volume       = {{8}},
  year         = {{2024}},
}

@article{62828,
  author       = {{Ruhm, Lukas and Löseke, Jannik and Vieth, Pascal and Prüßner, Tim and Grundmeier, Guido}},
  issn         = {{0169-4332}},
  journal      = {{Applied Surface Science}},
  publisher    = {{Elsevier BV}},
  title        = {{{Adhesion promotion and corrosion resistance of mixed phosphonic acid monolayers on AA 2024}}},
  doi          = {{10.1016/j.apsusc.2024.160655}},
  volume       = {{670}},
  year         = {{2024}},
}

@article{62942,
  abstract     = {{<jats:title>Abstract</jats:title><jats:p>Nanostructured bilayer thin films with superhydrophobic and superhydrophilic surfaces were prepared using Ti6Al4V alloy substrates which allowed for the comparative analysis of polyvinyl acetate (PVAc) particle adsorption as a function of the interface structure. The PVAc particles were obtained from emulsion polymerization of vinyl acetate. A superhydrophilic TiO<jats:sub>2</jats:sub> nanofiber-based 3D network was created on the Ti6Al4V alloy substrate by application of a hydrothermal method. Subsequent UV-grafting of ultra-thin polydimethylsiloxane (PDMS) layers resulted in a superhydrophobic surface. The modification steps were followed via Diffuse Reflectance Infrared Fourier Transform Spectroscopy, X-ray Photoelectron Spectroscopy, Field Emission-Scanning Electron Microscopy, contact angle and Electrochemical Impedance Spectroscopy. A mechanism for the adsorption of PVAc at the two electrolyte/substrate interfaces could be revealed.</jats:p>}},
  author       = {{Neßlinger, Vanessa and Atlanov, Jan and Grundmeier, Guido}},
  issn         = {{3004-9261}},
  journal      = {{Discover Applied Sciences}},
  number       = {{6}},
  publisher    = {{Springer Science and Business Media LLC}},
  title        = {{{Interactions of polyvinyl acetate dispersions with nanostructured superhydrophilic and superhydrophobic Ti6Al4V alloy surfaces}}},
  doi          = {{10.1007/s42452-024-05916-z}},
  volume       = {{6}},
  year         = {{2024}},
}

@article{48588,
  abstract     = {{<jats:p>Bacterial colonization and biofilm formation on abiotic surfaces are initiated by the adhesion of peptides and proteins. Understanding the adhesion of such peptides and proteins at a molecular level thus represents an important step toward controlling and suppressing biofilm formation on technological and medical materials. This study investigates the molecular adhesion of a pilus‐derived peptide that facilitates biofilm formation of Pseudomonas aeruginosa, a multidrug‐resistant opportunistic pathogen frequently encountered in healthcare settings. Single‐molecule force spectroscopy (SMFS) was performed on chemically etched ZnO surfaces to gather insights about peptide adsorption force and its kinetics. Metal‐free click chemistry for the fabrication of peptide‐terminated SMFS cantilevers was performed on amine‐terminated gold cantilevers and verified by X‐ray photoelectron spectroscopy (XPS) and polarization‐modulated infrared reflection absorption spectroscopy (PM‐IRRAS). Atomic force microscopy (AFM) and XPS analyses reveal stable topographies and surface chemistries of the substrates that are not affected by SMFS. Rupture events described by the worm‐like chain model (WLC) up to 600 pN were detected for the non‐polar ZnO(11‐20) surfaces. The dissociation barrier energy at zero force ΔG(0), the transition state distance xb and bound‐unbound dissociation rate at zero force koff(0) for the single crystalline substrate indicate that coordination and hydrogen bonds dominate the peptide/surface interaction.</jats:p>}},
  author       = {{Prüßner, Tim and Meinderink, Dennis and Zhu, Siqi and Orive, Alejandro G. and Kielar, Charlotte and Huck, Marten and Steinrück, Hans-Georg and Keller, Adrian and Grundmeier, Guido}},
  issn         = {{0947-6539}},
  journal      = {{Chemistry – A European Journal}},
  keywords     = {{General Chemistry, Catalysis, Organic Chemistry}},
  publisher    = {{Wiley}},
  title        = {{{Molecular Adhesion of a Pilus‐derived Peptide Involved in Pseudomonas aeruginosa Biofilm Formation on non‐polar ZnO Surfaces}}},
  doi          = {{10.1002/chem.202302464}},
  year         = {{2023}},
}

@article{44503,
  author       = {{Hanke, Marcel and Tomm, Emilia and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{1439-4227}},
  journal      = {{ChemBioChem}},
  keywords     = {{Organic Chemistry, Molecular Biology, Molecular Medicine, Biochemistry}},
  publisher    = {{Wiley}},
  title        = {{{Effect of Ionic Strength on the Thermal Stability of DNA Origami Nanostructures}}},
  doi          = {{10.1002/cbic.202300338}},
  year         = {{2023}},
}

@article{45828,
  abstract     = {{<jats:p>This article presents the potential-dependent adsorption of two proteins, bovine serum albumin (BSA) and lysozyme (LYZ), on Ti6Al4V alloy at pH 7.4 and 37 °C. The adsorption process was studied on an electropolished alloy under cathodic and anodic overpotentials, compared to the open circuit potential (OCP). To analyze the adsorption process, various complementary interface analytical techniques were employed, including PM-IRRAS (polarization-modulation infrared reflection-absorption spectroscopy), AFM (atomic force microscopy), XPS (X-ray photoelectron spectroscopy), and E-QCM (electrochemical quartz crystal microbalance) measurements. The polarization experiments were conducted within a potential range where charging of the electric double layer dominates, and Faradaic currents can be disregarded. The findings highlight the significant influence of the interfacial charge distribution on the adsorption of BSA and LYZ onto the alloy surface. Furthermore, electrochemical analysis of the protein layers formed under applied overpotentials demonstrated improved corrosion protection properties. These studies provide valuable insights into protein adsorption on titanium alloys under physiological conditions, characterized by varying potentials of the passive alloy.</jats:p>}},
  author       = {{Duderija, Belma and González-Orive, Alejandro and Ebbert, Christoph and Neßlinger, Vanessa and Keller, Adrian and Grundmeier, Guido}},
  issn         = {{1420-3049}},
  journal      = {{Molecules}},
  keywords     = {{Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science}},
  number       = {{13}},
  pages        = {{5109}},
  publisher    = {{MDPI AG}},
  title        = {{{Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy}}},
  doi          = {{10.3390/molecules28135109}},
  volume       = {{28}},
  year         = {{2023}},
}

@inbook{45829,
  author       = {{Keller, Adrian and Grundmeier, Guido}},
  booktitle    = {{Reference Module in Chemistry, Molecular Sciences and Chemical Engineering}},
  isbn         = {{9780124095472}},
  publisher    = {{Elsevier}},
  title        = {{{High-speed AFM studies of macromolecular dynamics at solid/liquid interfaces}}},
  doi          = {{10.1016/b978-0-323-85669-0.00123-9}},
  year         = {{2023}},
}

@article{46061,
  abstract     = {{<jats:p>DNA origami nanostructures have emerged as functional materials for applications in various areas of science and technology. In particular, the transfer of the DNA origami shape into inorganic materials using...</jats:p>}},
  author       = {{Pothineni, Bhanu Kiran and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2040-3364}},
  journal      = {{Nanoscale}},
  keywords     = {{General Materials Science}},
  publisher    = {{Royal Society of Chemistry (RSC)}},
  title        = {{{Cation-dependent assembly of hexagonal DNA origami lattices on SiO2 surfaces}}},
  doi          = {{10.1039/d3nr02926c}},
  year         = {{2023}},
}

@article{46480,
  author       = {{Müller, Hendrik and Weinberger, Christian and Grundmeier, Guido and de los Arcos de Pedro, Maria Teresa}},
  issn         = {{0368-2048}},
  journal      = {{Journal of Electron Spectroscopy and Related Phenomena}},
  keywords     = {{Physical and Theoretical Chemistry, Spectroscopy, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, Radiation, Electronic, Optical and Magnetic Materials}},
  publisher    = {{Elsevier BV}},
  title        = {{{UV-enhanced environmental charge compensation in near ambient pressure XPS}}},
  doi          = {{10.1016/j.elspec.2023.147317}},
  volume       = {{264}},
  year         = {{2023}},
}

@article{46542,
  abstract     = {{<jats:p>Multiprotein adsorption from complex body fluids represents a highly important and complicated phenomenon in medicine. In this work, multiprotein adsorption from diluted human serum at gold and oxidized iron surfaces is investigated at different serum concentrations and pH values. Adsorption-induced changes in surface topography and the total amount of adsorbed proteins are quantified by atomic force microscopy (AFM) and polarization-modulation infrared reflection absorption spectroscopy (PM-IRRAS), respectively. For both surfaces, stronger protein adsorption is observed at pH 6 compared to pH 7 and pH 8. PM-IRRAS furthermore provides some qualitative insights into the pH-dependent alterations in the composition of the adsorbed multiprotein films. Changes in the amide II/amide I band area ratio and in particular side-chain IR absorption suggest that the increased adsorption at pH 6 is accompanied by a change in protein film composition. Presumably, this is mostly driven by the adsorption of human serum albumin, which at pH 6 adsorbs more readily and thereby replaces other proteins with lower surface affinities in the resulting multiprotein film.</jats:p>}},
  author       = {{Huang, Jingyuan and Qiu, Yunshu and Lücke, Felix and Su, Jiangling and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{1420-3049}},
  journal      = {{Molecules}},
  keywords     = {{Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science}},
  number       = {{16}},
  publisher    = {{MDPI AG}},
  title        = {{{Multiprotein Adsorption from Human Serum at Gold and Oxidized Iron Surfaces Studied by Atomic Force Microscopy and Polarization-Modulation Infrared Reflection Absorption Spectroscopy}}},
  doi          = {{10.3390/molecules28166060}},
  volume       = {{28}},
  year         = {{2023}},
}

@article{46543,
  abstract     = {{<jats:p>The influence of nanoscale surface topography on protein adsorption is highly important for numerous applications in medicine and technology. Herein, ferritin adsorption at flat and nanofaceted, single-crystalline Al2O3 surfaces is investigated using atomic force microscopy and X-ray photoelectron spectroscopy. The nanofaceted surfaces are generated by the thermal annealing of Al2O3 wafers at temperatures above 1000 °C, which leads to the formation of faceted saw-tooth-like surface topographies with periodicities of about 160 nm and amplitudes of about 15 nm. Ferritin adsorption at these nanofaceted surfaces is notably suppressed compared to the flat surface at a concentration of 10 mg/mL, which is attributed to lower adsorption affinities of the newly formed facets. Consequently, adsorption is restricted mostly to the pattern grooves, where the proteins can maximize their contact area with the surface. However, this effect depends on the protein concentration, with an inverse trend being observed at 30 mg/mL. Furthermore, different ferritin adsorption behavior is observed at topographically similar nanofacet patterns fabricated at different annealing temperatures and attributed to different step and kink densities. These results demonstrate that while protein adsorption at solid surfaces can be notably affected by nanofacet patterns, fine-tuning protein adsorption in this way requires the precise control of facet properties.</jats:p>}},
  author       = {{Pothineni, Bhanu K. and Kollmann, Sabrina and Li, Xinyang and Grundmeier, Guido and Erb, Denise J. and Keller, Adrian}},
  issn         = {{1422-0067}},
  journal      = {{International Journal of Molecular Sciences}},
  keywords     = {{Inorganic Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Computer Science Applications, Spectroscopy, Molecular Biology, General Medicine, Catalysis}},
  number       = {{16}},
  publisher    = {{MDPI AG}},
  title        = {{{Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces}}},
  doi          = {{10.3390/ijms241612808}},
  volume       = {{24}},
  year         = {{2023}},
}