---
_id: '63436'
article_number: acsanm.5c04857
author:
- first_name: Sivoney Ferreira
  full_name: de Souza, Sivoney Ferreira
  last_name: de Souza
- first_name: Christina
  full_name: Beresowski, Christina
  last_name: Beresowski
- first_name: Sabine
  full_name: Kosmella, Sabine
  last_name: Kosmella
- first_name: João
  full_name: Ameixa, João
  last_name: Ameixa
- first_name: Bhanu Kiran
  full_name: Pothineni, Bhanu Kiran
  last_name: Pothineni
- first_name: Adrian Clemens
  full_name: Keller, Adrian Clemens
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Matthias
  full_name: Hartlieb, Matthias
  last_name: Hartlieb
- first_name: Andreas
  full_name: Taubert, Andreas
  last_name: Taubert
- first_name: Ilko
  full_name: Bald, Ilko
  last_name: Bald
citation:
  ama: de Souza SF, Beresowski C, Kosmella S, et al. Nanocellulose Membranes for Plasmon-Enhanced
    Removal of Organic Pollutants from Water. <i>ACS Applied Nano Materials</i>. Published
    online 2026. doi:<a href="https://doi.org/10.1021/acsanm.5c04857">10.1021/acsanm.5c04857</a>
  apa: de Souza, S. F., Beresowski, C., Kosmella, S., Ameixa, J., Pothineni, B. K.,
    Keller, A. C., Hartlieb, M., Taubert, A., &#38; Bald, I. (2026). Nanocellulose
    Membranes for Plasmon-Enhanced Removal of Organic Pollutants from Water. <i>ACS
    Applied Nano Materials</i>, Article acsanm.5c04857. <a href="https://doi.org/10.1021/acsanm.5c04857">https://doi.org/10.1021/acsanm.5c04857</a>
  bibtex: '@article{de Souza_Beresowski_Kosmella_Ameixa_Pothineni_Keller_Hartlieb_Taubert_Bald_2026,
    title={Nanocellulose Membranes for Plasmon-Enhanced Removal of Organic Pollutants
    from Water}, DOI={<a href="https://doi.org/10.1021/acsanm.5c04857">10.1021/acsanm.5c04857</a>},
    number={acsanm.5c04857}, journal={ACS Applied Nano Materials}, publisher={American
    Chemical Society (ACS)}, author={de Souza, Sivoney Ferreira and Beresowski, Christina
    and Kosmella, Sabine and Ameixa, João and Pothineni, Bhanu Kiran and Keller, Adrian
    Clemens and Hartlieb, Matthias and Taubert, Andreas and Bald, Ilko}, year={2026}
    }'
  chicago: Souza, Sivoney Ferreira de, Christina Beresowski, Sabine Kosmella, João
    Ameixa, Bhanu Kiran Pothineni, Adrian Clemens Keller, Matthias Hartlieb, Andreas
    Taubert, and Ilko Bald. “Nanocellulose Membranes for Plasmon-Enhanced Removal
    of Organic Pollutants from Water.” <i>ACS Applied Nano Materials</i>, 2026. <a
    href="https://doi.org/10.1021/acsanm.5c04857">https://doi.org/10.1021/acsanm.5c04857</a>.
  ieee: 'S. F. de Souza <i>et al.</i>, “Nanocellulose Membranes for Plasmon-Enhanced
    Removal of Organic Pollutants from Water,” <i>ACS Applied Nano Materials</i>,
    Art. no. acsanm.5c04857, 2026, doi: <a href="https://doi.org/10.1021/acsanm.5c04857">10.1021/acsanm.5c04857</a>.'
  mla: de Souza, Sivoney Ferreira, et al. “Nanocellulose Membranes for Plasmon-Enhanced
    Removal of Organic Pollutants from Water.” <i>ACS Applied Nano Materials</i>,
    acsanm.5c04857, American Chemical Society (ACS), 2026, doi:<a href="https://doi.org/10.1021/acsanm.5c04857">10.1021/acsanm.5c04857</a>.
  short: S.F. de Souza, C. Beresowski, S. Kosmella, J. Ameixa, B.K. Pothineni, A.C.
    Keller, M. Hartlieb, A. Taubert, I. Bald, ACS Applied Nano Materials (2026).
date_created: 2026-01-05T08:23:24Z
date_updated: 2026-01-05T08:23:51Z
department:
- _id: '302'
doi: 10.1021/acsanm.5c04857
language:
- iso: eng
publication: ACS Applied Nano Materials
publication_identifier:
  issn:
  - 2574-0970
  - 2574-0970
publication_status: published
publisher: American Chemical Society (ACS)
status: public
title: Nanocellulose Membranes for Plasmon-Enhanced Removal of Organic Pollutants
  from Water
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '62726'
abstract:
- lang: eng
  text: <jats:p>Surface-assisted DNA lattice assembly is used in the synthesis of
    functional surfaces and as a model of supramolecular network formation. Here,
    competitive DNA binding of different cation species is investigated...</jats:p>
author:
- first_name: Xiaodan
  full_name: Xu, Xiaodan
  last_name: Xu
- first_name: Bhanu Kiran
  full_name: Pothineni, Bhanu Kiran
  last_name: Pothineni
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Satoru
  full_name: Tsushima, Satoru
  last_name: Tsushima
- first_name: Adrian Clemens
  full_name: Keller, Adrian Clemens
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Xu X, Pothineni BK, Grundmeier G, Tsushima S, Keller AC. On the role of cation-DNA
    interactions in surface-assisted DNA lattice assembly. <i>Nanoscale</i>. Published
    online 2026. doi:<a href="https://doi.org/10.1039/d5nr03695j">10.1039/d5nr03695j</a>
  apa: Xu, X., Pothineni, B. K., Grundmeier, G., Tsushima, S., &#38; Keller, A. C.
    (2026). On the role of cation-DNA interactions in surface-assisted DNA lattice
    assembly. <i>Nanoscale</i>. <a href="https://doi.org/10.1039/d5nr03695j">https://doi.org/10.1039/d5nr03695j</a>
  bibtex: '@article{Xu_Pothineni_Grundmeier_Tsushima_Keller_2026, title={On the role
    of cation-DNA interactions in surface-assisted DNA lattice assembly}, DOI={<a
    href="https://doi.org/10.1039/d5nr03695j">10.1039/d5nr03695j</a>}, journal={Nanoscale},
    publisher={Royal Society of Chemistry (RSC)}, author={Xu, Xiaodan and Pothineni,
    Bhanu Kiran and Grundmeier, Guido and Tsushima, Satoru and Keller, Adrian Clemens},
    year={2026} }'
  chicago: Xu, Xiaodan, Bhanu Kiran Pothineni, Guido Grundmeier, Satoru Tsushima,
    and Adrian Clemens Keller. “On the Role of Cation-DNA Interactions in Surface-Assisted
    DNA Lattice Assembly.” <i>Nanoscale</i>, 2026. <a href="https://doi.org/10.1039/d5nr03695j">https://doi.org/10.1039/d5nr03695j</a>.
  ieee: 'X. Xu, B. K. Pothineni, G. Grundmeier, S. Tsushima, and A. C. Keller, “On
    the role of cation-DNA interactions in surface-assisted DNA lattice assembly,”
    <i>Nanoscale</i>, 2026, doi: <a href="https://doi.org/10.1039/d5nr03695j">10.1039/d5nr03695j</a>.'
  mla: Xu, Xiaodan, et al. “On the Role of Cation-DNA Interactions in Surface-Assisted
    DNA Lattice Assembly.” <i>Nanoscale</i>, Royal Society of Chemistry (RSC), 2026,
    doi:<a href="https://doi.org/10.1039/d5nr03695j">10.1039/d5nr03695j</a>.
  short: X. Xu, B.K. Pothineni, G. Grundmeier, S. Tsushima, A.C. Keller, Nanoscale
    (2026).
date_created: 2025-12-01T13:48:42Z
date_updated: 2026-01-06T10:42:32Z
department:
- _id: '302'
doi: 10.1039/d5nr03695j
language:
- iso: eng
publication: Nanoscale
publication_identifier:
  issn:
  - 2040-3364
  - 2040-3372
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: On the role of cation-DNA interactions in surface-assisted DNA lattice assembly
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '65082'
abstract:
- lang: eng
  text: <jats:p>Encoding information in molecular arrangements on DNA origami nanostructures
    (DONs) provides the basis for novel concepts in molecular data storage and computing.
    To preserve their integrity over long timescales, the information‐carrying DONs
    are often stored in a frozen state. Here, we investigate the effect of repeated
    freeze–thaw (F/T) cycles on the structural and functional integrity of DONs carrying
    biotin (Bt) modifications. Streptavidin (SAv) binding is used to visualize the
    stored information by atomic force microscopy (AFM) before and after 40 F/T cycles.
    Two strategies are compared by F/T cycling of (I) SAv‐bound DONs and (II) SAv‐free
    DONs that are exposed to SAv directly before AFM imaging. Our results reveal that
    while the DONs retain their overall shape, F/T cycling induces a small amount
    of damage, leading to slightly reduced SAv binding. Adding glycerol at mM concentrations
    efficiently protects the DONs and restores the original SAv binding yields. Nevertheless,
    SAv exposure after F/T cycling leads to slightly higher and more consistent SAv
    binding yields and a lower background of nonspecifically adsorbed SAv compared
    to Strategy I. This makes information readout by AFM more efficient and renders
    Strategy II more convenient for long‐term storage of information‐carrying DONs
    with repeated information readout.</jats:p>
article_number: e202500161
author:
- first_name: Xinyang
  full_name: Li, Xinyang
  last_name: Li
- first_name: Lukas
  full_name: Rabbe, Lukas
  last_name: Rabbe
- first_name: Jacqueline
  full_name: Linneweber, Jacqueline
  last_name: Linneweber
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian Clemens
  full_name: Keller, Adrian Clemens
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Li X, Rabbe L, Linneweber J, Grundmeier G, Keller AC. Stability of Information‐Carrying
    DNA Origami Nanostructures During Repeated Freeze–Thaw Cycles. <i>Chemistry–Methods</i>.
    2026;6(3). doi:<a href="https://doi.org/10.1002/cmtd.202500161">10.1002/cmtd.202500161</a>
  apa: Li, X., Rabbe, L., Linneweber, J., Grundmeier, G., &#38; Keller, A. C. (2026).
    Stability of Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw
    Cycles. <i>Chemistry–Methods</i>, <i>6</i>(3), Article e202500161. <a href="https://doi.org/10.1002/cmtd.202500161">https://doi.org/10.1002/cmtd.202500161</a>
  bibtex: '@article{Li_Rabbe_Linneweber_Grundmeier_Keller_2026, title={Stability of
    Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw Cycles},
    volume={6}, DOI={<a href="https://doi.org/10.1002/cmtd.202500161">10.1002/cmtd.202500161</a>},
    number={3e202500161}, journal={Chemistry–Methods}, publisher={Wiley}, author={Li,
    Xinyang and Rabbe, Lukas and Linneweber, Jacqueline and Grundmeier, Guido and
    Keller, Adrian Clemens}, year={2026} }'
  chicago: Li, Xinyang, Lukas Rabbe, Jacqueline Linneweber, Guido Grundmeier, and
    Adrian Clemens Keller. “Stability of Information‐Carrying DNA Origami Nanostructures
    During Repeated Freeze–Thaw Cycles.” <i>Chemistry–Methods</i> 6, no. 3 (2026).
    <a href="https://doi.org/10.1002/cmtd.202500161">https://doi.org/10.1002/cmtd.202500161</a>.
  ieee: 'X. Li, L. Rabbe, J. Linneweber, G. Grundmeier, and A. C. Keller, “Stability
    of Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw
    Cycles,” <i>Chemistry–Methods</i>, vol. 6, no. 3, Art. no. e202500161, 2026, doi:
    <a href="https://doi.org/10.1002/cmtd.202500161">10.1002/cmtd.202500161</a>.'
  mla: Li, Xinyang, et al. “Stability of Information‐Carrying DNA Origami Nanostructures
    During Repeated Freeze–Thaw Cycles.” <i>Chemistry–Methods</i>, vol. 6, no. 3,
    e202500161, Wiley, 2026, doi:<a href="https://doi.org/10.1002/cmtd.202500161">10.1002/cmtd.202500161</a>.
  short: X. Li, L. Rabbe, J. Linneweber, G. Grundmeier, A.C. Keller, Chemistry–Methods
    6 (2026).
date_created: 2026-03-23T07:12:13Z
date_updated: 2026-03-23T07:12:53Z
department:
- _id: '302'
doi: 10.1002/cmtd.202500161
intvolume: '         6'
issue: '3'
language:
- iso: eng
publication: Chemistry–Methods
publication_identifier:
  issn:
  - 2628-9725
  - 2628-9725
publication_status: published
publisher: Wiley
status: public
title: Stability of Information‐Carrying DNA Origami Nanostructures During Repeated
  Freeze–Thaw Cycles
type: journal_article
user_id: '48864'
volume: 6
year: '2026'
...
---
_id: '65108'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title>\r\n                  <jats:p>Lithographic
    surface patterning is a cornerstone of modern materials and device fabrication.
    Although the available lithography techniques are constantly being advanced to
    push the feature sizes down to the few-nanometer scale, such developments are
    associated with many technological and economic challenges. Combining established
    top-down lithography with bottom-up self-assembly strategies has the potential
    to overcome those challenges and enable the manipulation of matter with molecular
    precision. One of the most exciting approaches in this regard is to harness the
    programmability of DNA self-assembly to create precise DNA nanostructure masks
    to be used in the lithographic patterning of diverse substrates. DNA nanotechnology
    has provided us with a versatile toolbox for the high-yield synthesis of 2D and
    3D nanostructures with complex, user-defined shapes at unprecedented molecular
    accuracy. Consequently, the last decade has seen intense research efforts aimed
    at transferring such DNA nanostructure shapes into functional organic and inorganic
    materials and we have now arrived at a point where sophisticated molecular lithography
    approaches utilize DNA nanostructure masks for the fabrication of plasmonic surfaces
    for metamaterials and sensing applications. This review summarizes how the spatial
    information of such DNA nanostructure masks can be transferred into various organic
    and inorganic materials through selective etching and deposition steps. The review
    also discusses recent developments toward all-purpose molecular lithography schemes
    and highlights promising extensions of the discussed methods toward new materials
    systems and application fields.</jats:p>"
author:
- first_name: Adrian Clemens
  full_name: Keller, Adrian Clemens
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Veikko
  full_name: Linko, Veikko
  last_name: Linko
citation:
  ama: 'Keller AC, Linko V. Molecular lithography with DNA nanostructures: Methods
    and applications. <i>Journal of Physics D: Applied Physics</i>. Published online
    2026. doi:<a href="https://doi.org/10.1088/1361-6463/ae5667">10.1088/1361-6463/ae5667</a>'
  apa: 'Keller, A. C., &#38; Linko, V. (2026). Molecular lithography with DNA nanostructures:
    Methods and applications. <i>Journal of Physics D: Applied Physics</i>. <a href="https://doi.org/10.1088/1361-6463/ae5667">https://doi.org/10.1088/1361-6463/ae5667</a>'
  bibtex: '@article{Keller_Linko_2026, title={Molecular lithography with DNA nanostructures:
    Methods and applications}, DOI={<a href="https://doi.org/10.1088/1361-6463/ae5667">10.1088/1361-6463/ae5667</a>},
    journal={Journal of Physics D: Applied Physics}, publisher={IOP Publishing}, author={Keller,
    Adrian Clemens and Linko, Veikko}, year={2026} }'
  chicago: 'Keller, Adrian Clemens, and Veikko Linko. “Molecular Lithography with
    DNA Nanostructures: Methods and Applications.” <i>Journal of Physics D: Applied
    Physics</i>, 2026. <a href="https://doi.org/10.1088/1361-6463/ae5667">https://doi.org/10.1088/1361-6463/ae5667</a>.'
  ieee: 'A. C. Keller and V. Linko, “Molecular lithography with DNA nanostructures:
    Methods and applications,” <i>Journal of Physics D: Applied Physics</i>, 2026,
    doi: <a href="https://doi.org/10.1088/1361-6463/ae5667">10.1088/1361-6463/ae5667</a>.'
  mla: 'Keller, Adrian Clemens, and Veikko Linko. “Molecular Lithography with DNA
    Nanostructures: Methods and Applications.” <i>Journal of Physics D: Applied Physics</i>,
    IOP Publishing, 2026, doi:<a href="https://doi.org/10.1088/1361-6463/ae5667">10.1088/1361-6463/ae5667</a>.'
  short: 'A.C. Keller, V. Linko, Journal of Physics D: Applied Physics (2026).'
date_created: 2026-03-25T07:43:24Z
date_updated: 2026-03-25T07:44:52Z
department:
- _id: '302'
doi: 10.1088/1361-6463/ae5667
language:
- iso: eng
publication: 'Journal of Physics D: Applied Physics'
publication_identifier:
  issn:
  - 0022-3727
  - 1361-6463
publication_status: published
publisher: IOP Publishing
status: public
title: 'Molecular lithography with DNA nanostructures: Methods and applications'
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '59421'
author:
- first_name: Johannes
  full_name: Parikka, Johannes
  last_name: Parikka
- first_name: Bhanu Kiran
  full_name: Pothineni, Bhanu Kiran
  last_name: Pothineni
- first_name: Heini
  full_name: Järvinen, Heini
  last_name: Järvinen
- first_name: Kosti
  full_name: Tapio, Kosti
  last_name: Tapio
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: J. Jussi
  full_name: Toppari, J. Jussi
  last_name: Toppari
citation:
  ama: 'Parikka J, Pothineni BK, Järvinen H, Tapio K, Keller A, Toppari JJ. Surface-Assisted
    Assembly of DNA Origami Lattices on Silicon Wafers. In: <i>Methods in Molecular
    Biology</i>. Springer US; 2025. doi:<a href="https://doi.org/10.1007/978-1-0716-4394-5_7">10.1007/978-1-0716-4394-5_7</a>'
  apa: Parikka, J., Pothineni, B. K., Järvinen, H., Tapio, K., Keller, A., &#38; Toppari,
    J. J. (2025). Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers.
    In <i>Methods in Molecular Biology</i>. Springer US. <a href="https://doi.org/10.1007/978-1-0716-4394-5_7">https://doi.org/10.1007/978-1-0716-4394-5_7</a>
  bibtex: '@inbook{Parikka_Pothineni_Järvinen_Tapio_Keller_Toppari_2025, place={New
    York, NY}, title={Surface-Assisted Assembly of DNA Origami Lattices on Silicon
    Wafers}, DOI={<a href="https://doi.org/10.1007/978-1-0716-4394-5_7">10.1007/978-1-0716-4394-5_7</a>},
    booktitle={Methods in Molecular Biology}, publisher={Springer US}, author={Parikka,
    Johannes and Pothineni, Bhanu Kiran and Järvinen, Heini and Tapio, Kosti and Keller,
    Adrian and Toppari, J. Jussi}, year={2025} }'
  chicago: 'Parikka, Johannes, Bhanu Kiran Pothineni, Heini Järvinen, Kosti Tapio,
    Adrian Keller, and J. Jussi Toppari. “Surface-Assisted Assembly of DNA Origami
    Lattices on Silicon Wafers.” In <i>Methods in Molecular Biology</i>. New York,
    NY: Springer US, 2025. <a href="https://doi.org/10.1007/978-1-0716-4394-5_7">https://doi.org/10.1007/978-1-0716-4394-5_7</a>.'
  ieee: 'J. Parikka, B. K. Pothineni, H. Järvinen, K. Tapio, A. Keller, and J. J.
    Toppari, “Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers,”
    in <i>Methods in Molecular Biology</i>, New York, NY: Springer US, 2025.'
  mla: Parikka, Johannes, et al. “Surface-Assisted Assembly of DNA Origami Lattices
    on Silicon Wafers.” <i>Methods in Molecular Biology</i>, Springer US, 2025, doi:<a
    href="https://doi.org/10.1007/978-1-0716-4394-5_7">10.1007/978-1-0716-4394-5_7</a>.
  short: 'J. Parikka, B.K. Pothineni, H. Järvinen, K. Tapio, A. Keller, J.J. Toppari,
    in: Methods in Molecular Biology, Springer US, New York, NY, 2025.'
date_created: 2025-04-08T09:06:14Z
date_updated: 2025-04-08T09:06:34Z
department:
- _id: '302'
doi: 10.1007/978-1-0716-4394-5_7
language:
- iso: eng
place: New York, NY
publication: Methods in Molecular Biology
publication_identifier:
  isbn:
  - '9781071643938'
  - '9781071643945'
  issn:
  - 1064-3745
  - 1940-6029
publication_status: published
publisher: Springer US
status: public
title: Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers
type: book_chapter
user_id: '48864'
year: '2025'
...
---
_id: '59847'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title>\r\n          <jats:p>The surface-assisted
    assembly of DNA origami lattices is a potent method for creating molecular lithography
    masks. Lattice quality and assembly kinetics are controlled by various environmental
    parameters, including the employed surface, the assembly temperature, and the
    ionic composition of the buffer, with optimized parameter combinations resulting
    in highly ordered lattices that can span surface areas of several cm<jats:sup>2</jats:sup>.
    Established assembly protocols, however, employ assembly times ranging from hours
    to days. Here, the assembly of highly ordered hexagonal DNA origami lattices at
    mica surfaces is observed within few minutes using high-speed atomic force microscopy
    (HS-AFM). A moderate increase in the DNA origami concentration enables this rapid
    assembly. While forming a regular lattice takes 10 min at a DNA origami concentration
    of 4 nM, this time is shortened to about 2 min at a concentration of 6 nM. Increasing
    the DNA origami concentration any further does not result in shorter assembly
    times, presumably because DNA origami arrival at the mica surface is diffusion-limited.
    Over short length scales up to 1 µm, lattice order is independent of the DNA origami
    concentration. However, at larger length scales of a few microns, a DNA origami
    concentration of 10 nM yields slightly better order than lower and higher concentrations.
    Therefore, 10 nM can be considered the optimum concentration for the rapid assembly
    of highly ordered DNA origami lattices. These results thus represent an important
    step toward the industrial-scale application of DNA origami-based lithography
    masks.</jats:p>"
article_number: '77'
author:
- first_name: Bhanu Kiran
  full_name: Pothineni, Bhanu Kiran
  last_name: Pothineni
- first_name: Jörg
  full_name: Barner, Jörg
  last_name: Barner
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: David
  full_name: Contreras, David
  last_name: Contreras
- first_name: Mario
  full_name: Castro, Mario
  last_name: Castro
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Pothineni BK, Barner J, Grundmeier G, Contreras D, Castro M, Keller A. Rapid
    assembly of highly ordered DNA origami lattices at mica surfaces. <i>Discover
    Nano</i>. 2025;20(1). doi:<a href="https://doi.org/10.1186/s11671-025-04254-2">10.1186/s11671-025-04254-2</a>
  apa: Pothineni, B. K., Barner, J., Grundmeier, G., Contreras, D., Castro, M., &#38;
    Keller, A. (2025). Rapid assembly of highly ordered DNA origami lattices at mica
    surfaces. <i>Discover Nano</i>, <i>20</i>(1), Article 77. <a href="https://doi.org/10.1186/s11671-025-04254-2">https://doi.org/10.1186/s11671-025-04254-2</a>
  bibtex: '@article{Pothineni_Barner_Grundmeier_Contreras_Castro_Keller_2025, title={Rapid
    assembly of highly ordered DNA origami lattices at mica surfaces}, volume={20},
    DOI={<a href="https://doi.org/10.1186/s11671-025-04254-2">10.1186/s11671-025-04254-2</a>},
    number={177}, journal={Discover Nano}, publisher={Springer Science and Business
    Media LLC}, author={Pothineni, Bhanu Kiran and Barner, Jörg and Grundmeier, Guido
    and Contreras, David and Castro, Mario and Keller, Adrian}, year={2025} }'
  chicago: Pothineni, Bhanu Kiran, Jörg Barner, Guido Grundmeier, David Contreras,
    Mario Castro, and Adrian Keller. “Rapid Assembly of Highly Ordered DNA Origami
    Lattices at Mica Surfaces.” <i>Discover Nano</i> 20, no. 1 (2025). <a href="https://doi.org/10.1186/s11671-025-04254-2">https://doi.org/10.1186/s11671-025-04254-2</a>.
  ieee: 'B. K. Pothineni, J. Barner, G. Grundmeier, D. Contreras, M. Castro, and A.
    Keller, “Rapid assembly of highly ordered DNA origami lattices at mica surfaces,”
    <i>Discover Nano</i>, vol. 20, no. 1, Art. no. 77, 2025, doi: <a href="https://doi.org/10.1186/s11671-025-04254-2">10.1186/s11671-025-04254-2</a>.'
  mla: Pothineni, Bhanu Kiran, et al. “Rapid Assembly of Highly Ordered DNA Origami
    Lattices at Mica Surfaces.” <i>Discover Nano</i>, vol. 20, no. 1, 77, Springer
    Science and Business Media LLC, 2025, doi:<a href="https://doi.org/10.1186/s11671-025-04254-2">10.1186/s11671-025-04254-2</a>.
  short: B.K. Pothineni, J. Barner, G. Grundmeier, D. Contreras, M. Castro, A. Keller,
    Discover Nano 20 (2025).
date_created: 2025-05-08T07:17:29Z
date_updated: 2025-05-08T07:17:54Z
department:
- _id: '302'
doi: 10.1186/s11671-025-04254-2
intvolume: '        20'
issue: '1'
language:
- iso: eng
publication: Discover Nano
publication_identifier:
  issn:
  - 2731-9229
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Rapid assembly of highly ordered DNA origami lattices at mica surfaces
type: journal_article
user_id: '48864'
volume: 20
year: '2025'
...
---
_id: '59992'
abstract:
- lang: eng
  text: <jats:p>The immobilization of DNA origami nanostructures on solid surfaces
    is an important prerequisite for their application in many biosensors. So far,
    DNA origami immobilization has been investigated in detail only...</jats:p>
author:
- first_name: Xiaodan
  full_name: Xu, Xiaodan
  last_name: Xu
- first_name: Sandra Alicja
  full_name: Golebiowska, Sandra Alicja
  id: '69524'
  last_name: Golebiowska
- first_name: Teresa
  full_name: de los Arcos, Teresa
  last_name: de los Arcos
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Xu X, Golebiowska SA, de los Arcos T, Grundmeier G, Keller A. DNA origami adsorption
    at single-crystalline TiO2 surfaces. <i>RSC Applied Interfaces</i>. Published
    online 2025. doi:<a href="https://doi.org/10.1039/d5lf00109a">10.1039/d5lf00109a</a>
  apa: Xu, X., Golebiowska, S. A., de los Arcos, T., Grundmeier, G., &#38; Keller,
    A. (2025). DNA origami adsorption at single-crystalline TiO2 surfaces. <i>RSC
    Applied Interfaces</i>. <a href="https://doi.org/10.1039/d5lf00109a">https://doi.org/10.1039/d5lf00109a</a>
  bibtex: '@article{Xu_Golebiowska_de los Arcos_Grundmeier_Keller_2025, title={DNA
    origami adsorption at single-crystalline TiO2 surfaces}, DOI={<a href="https://doi.org/10.1039/d5lf00109a">10.1039/d5lf00109a</a>},
    journal={RSC Applied Interfaces}, publisher={Royal Society of Chemistry (RSC)},
    author={Xu, Xiaodan and Golebiowska, Sandra Alicja and de los Arcos, Teresa and
    Grundmeier, Guido and Keller, Adrian}, year={2025} }'
  chicago: Xu, Xiaodan, Sandra Alicja Golebiowska, Teresa de los Arcos, Guido Grundmeier,
    and Adrian Keller. “DNA Origami Adsorption at Single-Crystalline TiO2 Surfaces.”
    <i>RSC Applied Interfaces</i>, 2025. <a href="https://doi.org/10.1039/d5lf00109a">https://doi.org/10.1039/d5lf00109a</a>.
  ieee: 'X. Xu, S. A. Golebiowska, T. de los Arcos, G. Grundmeier, and A. Keller,
    “DNA origami adsorption at single-crystalline TiO2 surfaces,” <i>RSC Applied Interfaces</i>,
    2025, doi: <a href="https://doi.org/10.1039/d5lf00109a">10.1039/d5lf00109a</a>.'
  mla: Xu, Xiaodan, et al. “DNA Origami Adsorption at Single-Crystalline TiO2 Surfaces.”
    <i>RSC Applied Interfaces</i>, Royal Society of Chemistry (RSC), 2025, doi:<a
    href="https://doi.org/10.1039/d5lf00109a">10.1039/d5lf00109a</a>.
  short: X. Xu, S.A. Golebiowska, T. de los Arcos, G. Grundmeier, A. Keller, RSC Applied
    Interfaces (2025).
date_created: 2025-05-19T09:30:44Z
date_updated: 2025-05-19T09:32:05Z
department:
- _id: '302'
doi: 10.1039/d5lf00109a
language:
- iso: eng
publication: RSC Applied Interfaces
publication_identifier:
  issn:
  - 2755-3701
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: DNA origami adsorption at single-crystalline TiO2 surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '58613'
abstract:
- lang: eng
  text: Self-assembled DNA origami lattices on silicon oxide surfaces have great potential
    to serve as masks in molecular lithography. However, silicon oxide surfaces come
    in many different forms and the type and history of the silicon oxide has a large
    effect on its physicochemical surface properties. Therefore, we here investigate
    DNA origami lattice formation on differently fabricated SiOx films on silicon
    wafers after wet-chemical oxidation by RCA1. Despite having similar oxide compositions
    and hydroxylation states, of all surfaces tested, only thermally grown SiOx performs
    similarly well as native oxide. For the other SiOx films deposited by plasma-enhanced
    chemical vapor deposition and magnetron sputtering, DNA origami adsorption is
    strongly suppressed. This is attributed to an increased surface roughness and
    a lower oxide density, respectively. Our results demonstrate that the employed
    SiOx surface may decide over the outcome of an experiment and should be considered
    as an additional parameter that may require optimization and fine-tuning before
    high-quality lattices can be assembled. In particular, our observations suggest
    that efficient DNA origami lattice assembly on SiOx surfaces requires a low surface
    roughness and a high oxide density.
author:
- first_name: Bhanu Kiran
  full_name: Pothineni, Bhanu Kiran
  last_name: Pothineni
- first_name: Chantal
  full_name: Theile-Rasche, Chantal
  last_name: Theile-Rasche
- first_name: Hendrik
  full_name: Müller, Hendrik
  last_name: Müller
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Maria Teresa
  full_name: de los Arcos de Pedro, Maria Teresa
  id: '54556'
  last_name: de los Arcos de Pedro
  orcid: '0000-0002-8684-273X '
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Pothineni BK, Theile-Rasche C, Müller H, Grundmeier G, de los Arcos de Pedro
    MT, Keller A. DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces.
    <i>Chemistry – A European Journal</i>. Published online 2025:e202404108. doi:<a
    href="https://doi.org/10.1002/chem.202404108">10.1002/chem.202404108</a>
  apa: Pothineni, B. K., Theile-Rasche, C., Müller, H., Grundmeier, G., de los Arcos
    de Pedro, M. T., &#38; Keller, A. (2025). DNA Origami Adsorption and Lattice Formation
    on Different SiOx Surfaces. <i>Chemistry – A European Journal</i>, e202404108.
    <a href="https://doi.org/10.1002/chem.202404108">https://doi.org/10.1002/chem.202404108</a>
  bibtex: '@article{Pothineni_Theile-Rasche_Müller_Grundmeier_de los Arcos de Pedro_Keller_2025,
    title={DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces},
    DOI={<a href="https://doi.org/10.1002/chem.202404108">10.1002/chem.202404108</a>},
    journal={Chemistry – A European Journal}, author={Pothineni, Bhanu Kiran and Theile-Rasche,
    Chantal and Müller, Hendrik and Grundmeier, Guido and de los Arcos de Pedro, Maria
    Teresa and Keller, Adrian}, year={2025}, pages={e202404108} }'
  chicago: Pothineni, Bhanu Kiran, Chantal Theile-Rasche, Hendrik Müller, Guido Grundmeier,
    Maria Teresa de los Arcos de Pedro, and Adrian Keller. “DNA Origami Adsorption
    and Lattice Formation on Different SiOx Surfaces.” <i>Chemistry – A European Journal</i>,
    2025, e202404108. <a href="https://doi.org/10.1002/chem.202404108">https://doi.org/10.1002/chem.202404108</a>.
  ieee: 'B. K. Pothineni, C. Theile-Rasche, H. Müller, G. Grundmeier, M. T. de los
    Arcos de Pedro, and A. Keller, “DNA Origami Adsorption and Lattice Formation on
    Different SiOx Surfaces,” <i>Chemistry – A European Journal</i>, p. e202404108,
    2025, doi: <a href="https://doi.org/10.1002/chem.202404108">10.1002/chem.202404108</a>.'
  mla: Pothineni, Bhanu Kiran, et al. “DNA Origami Adsorption and Lattice Formation
    on Different SiOx Surfaces.” <i>Chemistry – A European Journal</i>, 2025, p. e202404108,
    doi:<a href="https://doi.org/10.1002/chem.202404108">10.1002/chem.202404108</a>.
  short: B.K. Pothineni, C. Theile-Rasche, H. Müller, G. Grundmeier, M.T. de los Arcos
    de Pedro, A. Keller, Chemistry – A European Journal (2025) e202404108.
date_created: 2025-02-12T14:49:48Z
date_updated: 2025-06-10T09:10:16Z
department:
- _id: '302'
doi: 10.1002/chem.202404108
language:
- iso: eng
page: e202404108
publication: Chemistry – A European Journal
status: public
title: DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60082'
author:
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Keller A. DNA origami nanostructures in biomedicine and the issue of stability.
    <i>Nucleic Acid Insights</i>. 2025;2(2):61–75. doi:<a href="https://doi.org/10.18609/nuc.2025.011">10.18609/nuc.2025.011</a>
  apa: Keller, A. (2025). DNA origami nanostructures in biomedicine and the issue
    of stability. <i>Nucleic Acid Insights</i>, <i>2</i>(2), 61–75. <a href="https://doi.org/10.18609/nuc.2025.011">https://doi.org/10.18609/nuc.2025.011</a>
  bibtex: '@article{Keller_2025, title={DNA origami nanostructures in biomedicine
    and the issue of stability}, volume={2}, DOI={<a href="https://doi.org/10.18609/nuc.2025.011">10.18609/nuc.2025.011</a>},
    number={2}, journal={Nucleic Acid Insights}, author={Keller, Adrian}, year={2025},
    pages={61–75} }'
  chicago: 'Keller, Adrian. “DNA Origami Nanostructures in Biomedicine and the Issue
    of Stability.” <i>Nucleic Acid Insights</i> 2, no. 2 (2025): 61–75. <a href="https://doi.org/10.18609/nuc.2025.011">https://doi.org/10.18609/nuc.2025.011</a>.'
  ieee: 'A. Keller, “DNA origami nanostructures in biomedicine and the issue of stability,”
    <i>Nucleic Acid Insights</i>, vol. 2, no. 2, pp. 61–75, 2025, doi: <a href="https://doi.org/10.18609/nuc.2025.011">10.18609/nuc.2025.011</a>.'
  mla: Keller, Adrian. “DNA Origami Nanostructures in Biomedicine and the Issue of
    Stability.” <i>Nucleic Acid Insights</i>, vol. 2, no. 2, 2025, pp. 61–75, doi:<a
    href="https://doi.org/10.18609/nuc.2025.011">10.18609/nuc.2025.011</a>.
  short: A. Keller, Nucleic Acid Insights 2 (2025) 61–75.
date_created: 2025-06-01T08:53:58Z
date_updated: 2025-06-10T09:09:28Z
ddc:
- '570'
department:
- _id: '302'
doi: 10.18609/nuc.2025.011
file:
- access_level: open_access
  content_type: application/pdf
  creator: adke
  date_created: 2025-06-01T08:53:35Z
  date_updated: 2025-06-01T08:53:35Z
  file_id: '60083'
  file_name: Keller_nai25.pdf
  file_size: 701125
  relation: main_file
file_date_updated: 2025-06-01T08:53:35Z
has_accepted_license: '1'
intvolume: '         2'
issue: '2'
language:
- iso: eng
oa: '1'
page: 61–75
publication: Nucleic Acid Insights
status: public
title: DNA origami nanostructures in biomedicine and the issue of stability
type: journal_article
user_id: '48864'
volume: 2
year: '2025'
...
---
_id: '58853'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title>\r\n          <jats:p>While being a promising
    approach for the treatment of infections caused by drug-resistant, pathogenic
    bacteria, the clinical implementation of phage therapy still faces several challenges.
    One of these challenges lies in the high strain-specificity of most bacteriophages,
    which makes it necessary to screen large phage collections against the target
    pathogens in order to identify suitable candidates for the formulations of personalized
    therapeutic phage cocktails. In this work, we evaluate the potential of quartz
    crystal microbalance with dissipation monitoring (QCM-D) to identify and detect
    phage infection and subsequent lysis of bacteria immobilized on the surfaces of
    the QCM-D sensors. Using lytic <jats:italic>Escherichia coli</jats:italic> phage
    T7 as a model, we show that phage infection of <jats:italic>E. coli</jats:italic>
    cells results in various unique alterations in the behaviors of the frequency
    (Δ<jats:italic>f</jats:italic>) and dissipation (Δ<jats:italic>D</jats:italic>)
    signals, which are not observed during exposure of the <jats:italic>E. coli</jats:italic>
    strain to non-infectious <jats:italic>Bacillus subtilis</jats:italic> phage phi29
    at similar concentration. To aid future phage screening campaigns, we furthermore
    identify a single measurement parameter, i.e., the spread between the different
    overtones of Δ<jats:italic>D</jats:italic>, that can be used to detect phage-induced
    lysis. For T7 infection of <jats:italic>E. coli</jats:italic>, this is achieved
    within 4 h after inoculation, including immobilization and growth of the bacteria
    on the sensor surface, as well as the completed phage propagation cycle. Given
    the commercial availability of highly automated multichannel systems and the fact
    that this approach does not require any sensor modifications, QCM-D has the potential
    to become a valuable tool for screening medium-sized phage collections against
    target pathogens.</jats:p>\r\n          <jats:p>\r\n            <jats:bold>Graphical
    Abstract</jats:bold>\r\n          </jats:p>"
author:
- first_name: Bhanu K.
  full_name: Pothineni, Bhanu K.
  last_name: Pothineni
- first_name: René
  full_name: Probst, René
  last_name: Probst
- first_name: Dorothee
  full_name: Kiefer, Dorothee
  last_name: Kiefer
- first_name: Verena
  full_name: Dobretzberger, Verena
  last_name: Dobretzberger
- first_name: Ivan
  full_name: Barišić, Ivan
  last_name: Barišić
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Pothineni BK, Probst R, Kiefer D, et al. Monitoring phage infection and lysis
    of surface-immobilized bacteria by QCM-D. <i>Analytical and Bioanalytical Chemistry</i>.
    Published online 2025. doi:<a href="https://doi.org/10.1007/s00216-025-05803-5">10.1007/s00216-025-05803-5</a>
  apa: Pothineni, B. K., Probst, R., Kiefer, D., Dobretzberger, V., Barišić, I.,
    Grundmeier, G., &#38; Keller, A. (2025). Monitoring phage infection and lysis
    of surface-immobilized bacteria by QCM-D. <i>Analytical and Bioanalytical Chemistry</i>.
    <a href="https://doi.org/10.1007/s00216-025-05803-5">https://doi.org/10.1007/s00216-025-05803-5</a>
  bibtex: '@article{Pothineni_Probst_Kiefer_Dobretzberger_Barišić_Grundmeier_Keller_2025,
    title={Monitoring phage infection and lysis of surface-immobilized bacteria by
    QCM-D}, DOI={<a href="https://doi.org/10.1007/s00216-025-05803-5">10.1007/s00216-025-05803-5</a>},
    journal={Analytical and Bioanalytical Chemistry}, publisher={Springer Science
    and Business Media LLC}, author={Pothineni, Bhanu K. and Probst, René and Kiefer,
    Dorothee and Dobretzberger, Verena and Barišić, Ivan and Grundmeier, Guido and
    Keller, Adrian}, year={2025} }'
  chicago: Pothineni, Bhanu K., René Probst, Dorothee Kiefer, Verena Dobretzberger,
    Ivan Barišić, Guido Grundmeier, and Adrian Keller. “Monitoring Phage Infection
    and Lysis of Surface-Immobilized Bacteria by QCM-D.” <i>Analytical and Bioanalytical
    Chemistry</i>, 2025. <a href="https://doi.org/10.1007/s00216-025-05803-5">https://doi.org/10.1007/s00216-025-05803-5</a>.
  ieee: 'B. K. Pothineni <i>et al.</i>, “Monitoring phage infection and lysis of surface-immobilized
    bacteria by QCM-D,” <i>Analytical and Bioanalytical Chemistry</i>, 2025, doi:
    <a href="https://doi.org/10.1007/s00216-025-05803-5">10.1007/s00216-025-05803-5</a>.'
  mla: Pothineni, Bhanu K., et al. “Monitoring Phage Infection and Lysis of Surface-Immobilized
    Bacteria by QCM-D.” <i>Analytical and Bioanalytical Chemistry</i>, Springer Science
    and Business Media LLC, 2025, doi:<a href="https://doi.org/10.1007/s00216-025-05803-5">10.1007/s00216-025-05803-5</a>.
  short: B.K. Pothineni, R. Probst, D. Kiefer, V. Dobretzberger, I. Barišić, G. Grundmeier,
    A. Keller, Analytical and Bioanalytical Chemistry (2025).
date_created: 2025-02-26T09:23:19Z
date_updated: 2025-02-26T09:23:43Z
department:
- _id: '302'
doi: 10.1007/s00216-025-05803-5
language:
- iso: eng
publication: Analytical and Bioanalytical Chemistry
publication_identifier:
  issn:
  - 1618-2642
  - 1618-2650
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Monitoring phage infection and lysis of surface-immobilized bacteria by QCM-D
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60507'
abstract:
- lang: eng
  text: <jats:p>DNA origami nanostructures are powerful molecular tools for the controlled
    arrangement of functional molecules and thus have important applications in biomedicine,
    sensing, and materials science. The fabrication of DNA origami...</jats:p>
author:
- first_name: Emilia
  full_name: Tomm, Emilia
  id: '68157'
  last_name: Tomm
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Tomm E, Grundmeier G, Keller A. Cost-efficient folding of functionalized DNA
    origami nanostructures via staple recycling. <i>Nanoscale</i>. Published online
    2025. doi:<a href="https://doi.org/10.1039/d5nr01435b">10.1039/d5nr01435b</a>
  apa: Tomm, E., Grundmeier, G., &#38; Keller, A. (2025). Cost-efficient folding of
    functionalized DNA origami nanostructures via staple recycling. <i>Nanoscale</i>.
    <a href="https://doi.org/10.1039/d5nr01435b">https://doi.org/10.1039/d5nr01435b</a>
  bibtex: '@article{Tomm_Grundmeier_Keller_2025, title={Cost-efficient folding of
    functionalized DNA origami nanostructures via staple recycling}, DOI={<a href="https://doi.org/10.1039/d5nr01435b">10.1039/d5nr01435b</a>},
    journal={Nanoscale}, publisher={Royal Society of Chemistry (RSC)}, author={Tomm,
    Emilia and Grundmeier, Guido and Keller, Adrian}, year={2025} }'
  chicago: Tomm, Emilia, Guido Grundmeier, and Adrian Keller. “Cost-Efficient Folding
    of Functionalized DNA Origami Nanostructures via Staple Recycling.” <i>Nanoscale</i>,
    2025. <a href="https://doi.org/10.1039/d5nr01435b">https://doi.org/10.1039/d5nr01435b</a>.
  ieee: 'E. Tomm, G. Grundmeier, and A. Keller, “Cost-efficient folding of functionalized
    DNA origami nanostructures via staple recycling,” <i>Nanoscale</i>, 2025, doi:
    <a href="https://doi.org/10.1039/d5nr01435b">10.1039/d5nr01435b</a>.'
  mla: Tomm, Emilia, et al. “Cost-Efficient Folding of Functionalized DNA Origami
    Nanostructures via Staple Recycling.” <i>Nanoscale</i>, Royal Society of Chemistry
    (RSC), 2025, doi:<a href="https://doi.org/10.1039/d5nr01435b">10.1039/d5nr01435b</a>.
  short: E. Tomm, G. Grundmeier, A. Keller, Nanoscale (2025).
date_created: 2025-07-03T11:26:30Z
date_updated: 2025-07-03T11:27:19Z
department:
- _id: '302'
doi: 10.1039/d5nr01435b
language:
- iso: eng
publication: Nanoscale
publication_identifier:
  issn:
  - 2040-3364
  - 2040-3372
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Cost-efficient folding of functionalized DNA origami nanostructures via staple
  recycling
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60606'
abstract:
- lang: eng
  text: <jats:p>Streptavidin binding to DNA origami-supported high-density biotin
    arrays is investigated for selected experimental parameters. While bidentate binding
    and steric hindrance can be minimized, molecular crowding limits the binding yields
    in 2D arrays.</jats:p>
author:
- first_name: Lukas
  full_name: Rabbe, Lukas
  last_name: Rabbe
- first_name: Emilia
  full_name: Tomm, Emilia
  id: '68157'
  last_name: Tomm
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Rabbe L, Tomm E, Grundmeier G, Keller A. Toward high-density streptavidin arrays
    on DNA origami nanostructures. <i>RSC Advances</i>. 2025;15(30):24536-24543. doi:<a
    href="https://doi.org/10.1039/d5ra03393d">10.1039/d5ra03393d</a>
  apa: Rabbe, L., Tomm, E., Grundmeier, G., &#38; Keller, A. (2025). Toward high-density
    streptavidin arrays on DNA origami nanostructures. <i>RSC Advances</i>, <i>15</i>(30),
    24536–24543. <a href="https://doi.org/10.1039/d5ra03393d">https://doi.org/10.1039/d5ra03393d</a>
  bibtex: '@article{Rabbe_Tomm_Grundmeier_Keller_2025, title={Toward high-density
    streptavidin arrays on DNA origami nanostructures}, volume={15}, DOI={<a href="https://doi.org/10.1039/d5ra03393d">10.1039/d5ra03393d</a>},
    number={30}, journal={RSC Advances}, publisher={Royal Society of Chemistry (RSC)},
    author={Rabbe, Lukas and Tomm, Emilia and Grundmeier, Guido and Keller, Adrian},
    year={2025}, pages={24536–24543} }'
  chicago: 'Rabbe, Lukas, Emilia Tomm, Guido Grundmeier, and Adrian Keller. “Toward
    High-Density Streptavidin Arrays on DNA Origami Nanostructures.” <i>RSC Advances</i>
    15, no. 30 (2025): 24536–43. <a href="https://doi.org/10.1039/d5ra03393d">https://doi.org/10.1039/d5ra03393d</a>.'
  ieee: 'L. Rabbe, E. Tomm, G. Grundmeier, and A. Keller, “Toward high-density streptavidin
    arrays on DNA origami nanostructures,” <i>RSC Advances</i>, vol. 15, no. 30, pp.
    24536–24543, 2025, doi: <a href="https://doi.org/10.1039/d5ra03393d">10.1039/d5ra03393d</a>.'
  mla: Rabbe, Lukas, et al. “Toward High-Density Streptavidin Arrays on DNA Origami
    Nanostructures.” <i>RSC Advances</i>, vol. 15, no. 30, Royal Society of Chemistry
    (RSC), 2025, pp. 24536–43, doi:<a href="https://doi.org/10.1039/d5ra03393d">10.1039/d5ra03393d</a>.
  short: L. Rabbe, E. Tomm, G. Grundmeier, A. Keller, RSC Advances 15 (2025) 24536–24543.
date_created: 2025-07-15T06:06:48Z
date_updated: 2025-07-15T06:07:16Z
department:
- _id: '302'
doi: 10.1039/d5ra03393d
intvolume: '        15'
issue: '30'
language:
- iso: eng
page: 24536-24543
publication: RSC Advances
publication_identifier:
  issn:
  - 2046-2069
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Toward high-density streptavidin arrays on DNA origami nanostructures
type: journal_article
user_id: '48864'
volume: 15
year: '2025'
...
---
_id: '60709'
abstract:
- lang: eng
  text: <jats:p>Self-assembled DNA origami lattices have promising applications in
    the fabrication of functional surfaces for sensing and plasmonics via molecular
    lithography. While surface-assisted DNA origami lattice assembly at mica surfaces
    is...</jats:p>
author:
- first_name: Adekunle
  full_name: Omoboye, Adekunle
  last_name: Omoboye
- first_name: Bhanu
  full_name: Pothineni, Bhanu
  last_name: Pothineni
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Zhe
  full_name: She, Zhe
  last_name: She
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Omoboye A, Pothineni B, Grundmeier G, She Z, Keller A. Surface potential-dependent
    assembly of DNA origami lattices at SiO2 surfaces. <i>RSC Applied Interfaces</i>.
    Published online 2025. doi:<a href="https://doi.org/10.1039/d5lf00169b">10.1039/d5lf00169b</a>
  apa: Omoboye, A., Pothineni, B., Grundmeier, G., She, Z., &#38; Keller, A. (2025).
    Surface potential-dependent assembly of DNA origami lattices at SiO2 surfaces.
    <i>RSC Applied Interfaces</i>. <a href="https://doi.org/10.1039/d5lf00169b">https://doi.org/10.1039/d5lf00169b</a>
  bibtex: '@article{Omoboye_Pothineni_Grundmeier_She_Keller_2025, title={Surface potential-dependent
    assembly of DNA origami lattices at SiO2 surfaces}, DOI={<a href="https://doi.org/10.1039/d5lf00169b">10.1039/d5lf00169b</a>},
    journal={RSC Applied Interfaces}, publisher={Royal Society of Chemistry (RSC)},
    author={Omoboye, Adekunle and Pothineni, Bhanu and Grundmeier, Guido and She,
    Zhe and Keller, Adrian}, year={2025} }'
  chicago: Omoboye, Adekunle, Bhanu Pothineni, Guido Grundmeier, Zhe She, and Adrian
    Keller. “Surface Potential-Dependent Assembly of DNA Origami Lattices at SiO2
    Surfaces.” <i>RSC Applied Interfaces</i>, 2025. <a href="https://doi.org/10.1039/d5lf00169b">https://doi.org/10.1039/d5lf00169b</a>.
  ieee: 'A. Omoboye, B. Pothineni, G. Grundmeier, Z. She, and A. Keller, “Surface
    potential-dependent assembly of DNA origami lattices at SiO2 surfaces,” <i>RSC
    Applied Interfaces</i>, 2025, doi: <a href="https://doi.org/10.1039/d5lf00169b">10.1039/d5lf00169b</a>.'
  mla: Omoboye, Adekunle, et al. “Surface Potential-Dependent Assembly of DNA Origami
    Lattices at SiO2 Surfaces.” <i>RSC Applied Interfaces</i>, Royal Society of Chemistry
    (RSC), 2025, doi:<a href="https://doi.org/10.1039/d5lf00169b">10.1039/d5lf00169b</a>.
  short: A. Omoboye, B. Pothineni, G. Grundmeier, Z. She, A. Keller, RSC Applied Interfaces
    (2025).
date_created: 2025-07-22T07:17:24Z
date_updated: 2025-07-22T07:18:04Z
department:
- _id: '302'
doi: 10.1039/d5lf00169b
language:
- iso: eng
publication: RSC Applied Interfaces
publication_identifier:
  issn:
  - 2755-3701
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Surface potential-dependent assembly of DNA origami lattices at SiO2 surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60973'
abstract:
- lang: eng
  text: <jats:p>The specific binding of DNA origami nanostructures (DONs) to bacteria
    is an important prerequisite for their application in pathogen targeting and antimicrobial
    drug delivery. So far, targeting bacteria with DONs has been achieved exclusively
    via aptamers, which suffer from drawbacks such as sensitivity toward environmental
    conditions and reduced binding after immobilization or conjugation. Here, an alternative
    approach is presented based on the modification of DONs with the cell wall‐binding
    glycopeptide antibiotic vancomycin. Using strain‐promoted azide‐alkyne cycloaddition,
    azide‐modified vancomycin is conjugated to selected staple strands and subsequently
    incorporated into 2D DON triangles. The resulting constructs show specific binding
    to the Gram‐positive species <jats:italic>Bacillus subtilis</jats:italic> (<jats:italic>B.
    subtilis</jats:italic>) and <jats:italic>Staphylococcus capitis</jats:italic>
    (<jats:italic>S. capitis</jats:italic>), and remarkably, to Gram‐negative <jats:italic>Escherichia
    coli</jats:italic> (<jats:italic>E. coli</jats:italic>), but no antimicrobial
    activity at vancomycin concentrations up to at least 2.91 μM. For <jats:italic>B.
    subtilis</jats:italic> and <jats:italic>E. coli</jats:italic>, DONs with vancomycin
    modifications on both sides exhibit better binding than DONs modified on only
    one side. However, both variants bind equally well to <jats:italic>S. capitis</jats:italic>.
    These results demonstrate the great potential of small molecule drug compounds
    for the robust, broad‐spectrum targeting of bacteria with DONs. Targeting a ubiquitous
    cell wall component of most pathogenic bacteria, vancomycin‐modified DONs have
    many potential applications in the prevention and treatment of nosocomial infections.</jats:p>
article_number: '2500246'
author:
- first_name: Özge
  full_name: Coşkuner Leineweber, Özge
  last_name: Coşkuner Leineweber
- first_name: Bhanu K.
  full_name: Pothineni, Bhanu K.
  last_name: Pothineni
- first_name: Nils
  full_name: Schumann, Nils
  last_name: Schumann
- first_name: Ulrike
  full_name: Hofmann, Ulrike
  last_name: Hofmann
- first_name: Christin
  full_name: Möser, Christin
  last_name: Möser
- first_name: David M.
  full_name: Smith, David M.
  last_name: Smith
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Yixin
  full_name: Zhang, Yixin
  last_name: Zhang
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Coşkuner Leineweber Ö, Pothineni BK, Schumann N, et al. Vancomycin‐Modified
    DNA Origami Nanostructures for Targeting Bacterial Pathogens. <i>Small Structures</i>.
    Published online 2025. doi:<a href="https://doi.org/10.1002/sstr.202500246">10.1002/sstr.202500246</a>
  apa: Coşkuner Leineweber, Ö., Pothineni, B. K., Schumann, N., Hofmann, U., Möser,
    C., Smith, D. M., Grundmeier, G., Zhang, Y., &#38; Keller, A. (2025). Vancomycin‐Modified
    DNA Origami Nanostructures for Targeting Bacterial Pathogens. <i>Small Structures</i>,
    Article 2500246. <a href="https://doi.org/10.1002/sstr.202500246">https://doi.org/10.1002/sstr.202500246</a>
  bibtex: '@article{Coşkuner Leineweber_Pothineni_Schumann_Hofmann_Möser_Smith_Grundmeier_Zhang_Keller_2025,
    title={Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial
    Pathogens}, DOI={<a href="https://doi.org/10.1002/sstr.202500246">10.1002/sstr.202500246</a>},
    number={2500246}, journal={Small Structures}, publisher={Wiley}, author={Coşkuner
    Leineweber, Özge and Pothineni, Bhanu K. and Schumann, Nils and Hofmann, Ulrike
    and Möser, Christin and Smith, David M. and Grundmeier, Guido and Zhang, Yixin
    and Keller, Adrian}, year={2025} }'
  chicago: Coşkuner Leineweber, Özge, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann,
    Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, and Adrian Keller.
    “Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens.”
    <i>Small Structures</i>, 2025. <a href="https://doi.org/10.1002/sstr.202500246">https://doi.org/10.1002/sstr.202500246</a>.
  ieee: 'Ö. Coşkuner Leineweber <i>et al.</i>, “Vancomycin‐Modified DNA Origami Nanostructures
    for Targeting Bacterial Pathogens,” <i>Small Structures</i>, Art. no. 2500246,
    2025, doi: <a href="https://doi.org/10.1002/sstr.202500246">10.1002/sstr.202500246</a>.'
  mla: Coşkuner Leineweber, Özge, et al. “Vancomycin‐Modified DNA Origami Nanostructures
    for Targeting Bacterial Pathogens.” <i>Small Structures</i>, 2500246, Wiley, 2025,
    doi:<a href="https://doi.org/10.1002/sstr.202500246">10.1002/sstr.202500246</a>.
  short: Ö. Coşkuner Leineweber, B.K. Pothineni, N. Schumann, U. Hofmann, C. Möser,
    D.M. Smith, G. Grundmeier, Y. Zhang, A. Keller, Small Structures (2025).
date_created: 2025-08-22T06:02:45Z
date_updated: 2025-08-22T06:04:06Z
department:
- _id: '302'
doi: 10.1002/sstr.202500246
language:
- iso: eng
publication: Small Structures
publication_identifier:
  issn:
  - 2688-4062
  - 2688-4062
publication_status: published
publisher: Wiley
status: public
title: Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '61821'
abstract:
- lang: eng
  text: <jats:title>Abstract</jats:title><jats:p>Controlling the surface orientation
    of DNA origami nanostructures (DON) is crucial for applications in nanotechnology
    and materials science. While previous work utilized various DON modifications,
    simple methods for controlling their landing orientation remain scarce. Here,
    we demonstrate a straightforward approach to control the adsorption orientation
    of chiral double‐L (CDL) DON on mica by tuning magnesium ion (Mg<jats:sup>2</jats:sup>⁺)
    concentration and exploiting global shape distortions. Using atomic force microscopy
    (AFM), we analyzed the resulting distribution of the mirror‐image orientations,
    referred to as S and Z orientations, at both buffer/mica and air/mica interfaces
    and identified conditions resulting in homogenous CDL orientation of 100% S. These
    results demonstrate how DON conformation and ionic environments influence DON
    orientation, offering insights for precise nanostructure deposition.</jats:p>
article_number: e202507613
author:
- first_name: Gangamallaiah
  full_name: Velpula, Gangamallaiah
  last_name: Velpula
- first_name: Emilia
  full_name: Tomm, Emilia
  last_name: Tomm
- first_name: Boxuan
  full_name: Shen, Boxuan
  last_name: Shen
- first_name: Kunal S.
  full_name: Mali, Kunal S.
  last_name: Mali
- first_name: Adrian Clemens
  full_name: Keller, Adrian Clemens
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Steven
  full_name: De Feyter, Steven
  last_name: De Feyter
citation:
  ama: Velpula G, Tomm E, Shen B, Mali KS, Keller AC, De Feyter S. Breaking of the
    Up‐Down Symmetry of DNA Origami on a Solid Substrate. <i>Angewandte Chemie International
    Edition</i>. Published online 2025. doi:<a href="https://doi.org/10.1002/anie.202507613">10.1002/anie.202507613</a>
  apa: Velpula, G., Tomm, E., Shen, B., Mali, K. S., Keller, A. C., &#38; De Feyter,
    S. (2025). Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate.
    <i>Angewandte Chemie International Edition</i>, Article e202507613. <a href="https://doi.org/10.1002/anie.202507613">https://doi.org/10.1002/anie.202507613</a>
  bibtex: '@article{Velpula_Tomm_Shen_Mali_Keller_De Feyter_2025, title={Breaking
    of the Up‐Down Symmetry of DNA Origami on a Solid Substrate}, DOI={<a href="https://doi.org/10.1002/anie.202507613">10.1002/anie.202507613</a>},
    number={e202507613}, journal={Angewandte Chemie International Edition}, publisher={Wiley},
    author={Velpula, Gangamallaiah and Tomm, Emilia and Shen, Boxuan and Mali, Kunal
    S. and Keller, Adrian Clemens and De Feyter, Steven}, year={2025} }'
  chicago: Velpula, Gangamallaiah, Emilia Tomm, Boxuan Shen, Kunal S. Mali, Adrian
    Clemens Keller, and Steven De Feyter. “Breaking of the Up‐Down Symmetry of DNA
    Origami on a Solid Substrate.” <i>Angewandte Chemie International Edition</i>,
    2025. <a href="https://doi.org/10.1002/anie.202507613">https://doi.org/10.1002/anie.202507613</a>.
  ieee: 'G. Velpula, E. Tomm, B. Shen, K. S. Mali, A. C. Keller, and S. De Feyter,
    “Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate,” <i>Angewandte
    Chemie International Edition</i>, Art. no. e202507613, 2025, doi: <a href="https://doi.org/10.1002/anie.202507613">10.1002/anie.202507613</a>.'
  mla: Velpula, Gangamallaiah, et al. “Breaking of the Up‐Down Symmetry of DNA Origami
    on a Solid Substrate.” <i>Angewandte Chemie International Edition</i>, e202507613,
    Wiley, 2025, doi:<a href="https://doi.org/10.1002/anie.202507613">10.1002/anie.202507613</a>.
  short: G. Velpula, E. Tomm, B. Shen, K.S. Mali, A.C. Keller, S. De Feyter, Angewandte
    Chemie International Edition (2025).
date_created: 2025-10-13T13:53:22Z
date_updated: 2025-10-13T13:55:05Z
department:
- _id: '302'
doi: 10.1002/anie.202507613
language:
- iso: eng
publication: Angewandte Chemie International Edition
publication_identifier:
  issn:
  - 1433-7851
  - 1521-3773
publication_status: published
publisher: Wiley
status: public
title: Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '51121'
abstract:
- lang: eng
  text: <jats:p>DNA origami nanostructures are a powerful tool in biomedicine and
    can be used to combat drug‐resistant bacterial infections. However, the effect
    of unmodified DNA origami nanostructures on bacteria is yet to be elucidated.
    With the aim to obtain a better understanding of this phenomenon, the effect of
    three DNA origami shapes, i.e., DNA origami triangles, six‐helix bundles (6HBs),
    and 24‐helix bundles (24HBs), on the growth of Gram‐negative Escherichia coli
    and Gram‐positive Bacillus subtilis is investigated. These results reveal that
    while triangles and 24HBs can be used as a source of nutrients by E. coli and
    thereby promote population growth, their effect is much smaller than that of genomic
    single‐ and double‐stranded DNA. However, no effect on E. coli population growth
    is observed for the 6HBs. On the other hand, B. subtilis does not show any significant
    changes in population growth when cultured with the different DNA origami shapes
    or genomic DNA. The detailed effect of DNA origami nanostructures on bacterial
    growth thus depends on the competence signals and uptake mechanism of each bacterial
    species, as well as the DNA origami shape. This should be considered in the development
    of antimicrobial DNA origami nanostructures.</jats:p>
author:
- first_name: Jaime Andres
  full_name: Garcia-Diosa, Jaime Andres
  last_name: Garcia-Diosa
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Garcia-Diosa JA, Grundmeier G, Keller A. Effect of DNA Origami Nanostructures
    on Bacterial Growth. <i>ChemBioChem</i>. Published online 2024. doi:<a href="https://doi.org/10.1002/cbic.202400091">10.1002/cbic.202400091</a>
  apa: Garcia-Diosa, J. A., Grundmeier, G., &#38; Keller, A. (2024). Effect of DNA
    Origami Nanostructures on Bacterial Growth. <i>ChemBioChem</i>. <a href="https://doi.org/10.1002/cbic.202400091">https://doi.org/10.1002/cbic.202400091</a>
  bibtex: '@article{Garcia-Diosa_Grundmeier_Keller_2024, title={Effect of DNA Origami
    Nanostructures on Bacterial Growth}, DOI={<a href="https://doi.org/10.1002/cbic.202400091">10.1002/cbic.202400091</a>},
    journal={ChemBioChem}, publisher={Wiley}, author={Garcia-Diosa, Jaime Andres and
    Grundmeier, Guido and Keller, Adrian}, year={2024} }'
  chicago: Garcia-Diosa, Jaime Andres, Guido Grundmeier, and Adrian Keller. “Effect
    of DNA Origami Nanostructures on Bacterial Growth.” <i>ChemBioChem</i>, 2024.
    <a href="https://doi.org/10.1002/cbic.202400091">https://doi.org/10.1002/cbic.202400091</a>.
  ieee: 'J. A. Garcia-Diosa, G. Grundmeier, and A. Keller, “Effect of DNA Origami
    Nanostructures on Bacterial Growth,” <i>ChemBioChem</i>, 2024, doi: <a href="https://doi.org/10.1002/cbic.202400091">10.1002/cbic.202400091</a>.'
  mla: Garcia-Diosa, Jaime Andres, et al. “Effect of DNA Origami Nanostructures on
    Bacterial Growth.” <i>ChemBioChem</i>, Wiley, 2024, doi:<a href="https://doi.org/10.1002/cbic.202400091">10.1002/cbic.202400091</a>.
  short: J.A. Garcia-Diosa, G. Grundmeier, A. Keller, ChemBioChem (2024).
date_created: 2024-02-03T12:41:16Z
date_updated: 2024-02-03T12:42:48Z
department:
- _id: '302'
doi: 10.1002/cbic.202400091
keyword:
- Organic Chemistry
- Molecular Biology
- Molecular Medicine
- Biochemistry
language:
- iso: eng
publication: ChemBioChem
publication_identifier:
  issn:
  - 1439-4227
  - 1439-7633
publication_status: published
publisher: Wiley
status: public
title: Effect of DNA Origami Nanostructures on Bacterial Growth
type: journal_article
user_id: '48864'
year: '2024'
...
---
_id: '53621'
abstract:
- lang: eng
  text: <jats:p>The coupling of structural transitions to heat capacity changes leads
    to destabilization of macromolecules at both, elevated and lowered temperatures.
    DNA origami not only exhibit this property but also provide...</jats:p>
author:
- first_name: Daniel
  full_name: Dornbusch, Daniel
  last_name: Dornbusch
- first_name: Marcel
  full_name: Hanke, Marcel
  last_name: Hanke
- first_name: Emilia
  full_name: Tomm, Emilia
  id: '68157'
  last_name: Tomm
- first_name: Charlotte
  full_name: Kielar, Charlotte
  last_name: Kielar
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Karim
  full_name: Fahmy, Karim
  last_name: Fahmy
citation:
  ama: Dornbusch D, Hanke M, Tomm E, et al. Cold denaturation of DNA origami nanostructures.
    <i>Chemical Communications</i>. Published online 2024. doi:<a href="https://doi.org/10.1039/d3cc05985e">10.1039/d3cc05985e</a>
  apa: Dornbusch, D., Hanke, M., Tomm, E., Kielar, C., Grundmeier, G., Keller, A.,
    &#38; Fahmy, K. (2024). Cold denaturation of DNA origami nanostructures. <i>Chemical
    Communications</i>. <a href="https://doi.org/10.1039/d3cc05985e">https://doi.org/10.1039/d3cc05985e</a>
  bibtex: '@article{Dornbusch_Hanke_Tomm_Kielar_Grundmeier_Keller_Fahmy_2024, title={Cold
    denaturation of DNA origami nanostructures}, DOI={<a href="https://doi.org/10.1039/d3cc05985e">10.1039/d3cc05985e</a>},
    journal={Chemical Communications}, publisher={Royal Society of Chemistry (RSC)},
    author={Dornbusch, Daniel and Hanke, Marcel and Tomm, Emilia and Kielar, Charlotte
    and Grundmeier, Guido and Keller, Adrian and Fahmy, Karim}, year={2024} }'
  chicago: Dornbusch, Daniel, Marcel Hanke, Emilia Tomm, Charlotte Kielar, Guido Grundmeier,
    Adrian Keller, and Karim Fahmy. “Cold Denaturation of DNA Origami Nanostructures.”
    <i>Chemical Communications</i>, 2024. <a href="https://doi.org/10.1039/d3cc05985e">https://doi.org/10.1039/d3cc05985e</a>.
  ieee: 'D. Dornbusch <i>et al.</i>, “Cold denaturation of DNA origami nanostructures,”
    <i>Chemical Communications</i>, 2024, doi: <a href="https://doi.org/10.1039/d3cc05985e">10.1039/d3cc05985e</a>.'
  mla: Dornbusch, Daniel, et al. “Cold Denaturation of DNA Origami Nanostructures.”
    <i>Chemical Communications</i>, Royal Society of Chemistry (RSC), 2024, doi:<a
    href="https://doi.org/10.1039/d3cc05985e">10.1039/d3cc05985e</a>.
  short: D. Dornbusch, M. Hanke, E. Tomm, C. Kielar, G. Grundmeier, A. Keller, K.
    Fahmy, Chemical Communications (2024).
date_created: 2024-04-23T08:20:05Z
date_updated: 2024-04-23T08:21:05Z
department:
- _id: '302'
doi: 10.1039/d3cc05985e
keyword:
- Materials Chemistry
- Metals and Alloys
- Surfaces
- Coatings and Films
- General Chemistry
- Ceramics and Composites
- Electronic
- Optical and Magnetic Materials
- Catalysis
language:
- iso: eng
publication: Chemical Communications
publication_identifier:
  issn:
  - 1359-7345
  - 1364-548X
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Cold denaturation of DNA origami nanostructures
type: journal_article
user_id: '48864'
year: '2024'
...
---
_id: '54644'
abstract:
- lang: eng
  text: <jats:p>DNA origami nanostructures (DONs) are able to scavenge reactive oxygen
    species (ROS) and their scavenging efficiency toward ROS radicals was shown to
    be comparable to that of genomic DNA. Herein, we demonstrate that DONs are highly
    efficient singlet oxygen quenchers outperforming double‐stranded (ds) DNA by several
    orders of magnitude. To this end, a ROS mixture rich in singlet oxygen is generated
    by light irradiation of the photosensitizer methylene blue and its cytotoxic effect
    on Escherichia coli cells is quantified in the presence and absence of DONs. DONs
    are found to be vastly superior to dsDNA in protecting the bacteria from ROS‐induced
    damage and even surpass established ROS scavengers. At a concentration of 15 nM,
    DONs are about 50 000 times more efficient ROS scavengers than dsDNA at an equivalent
    concentration. This is attributed to the dominant role of singlet oxygen, which
    has a long diffusion length and reacts specifically with guanine. The dense packing
    of the available guanines into the small volume of the DON increases the overall
    quenching probability compared to a linear dsDNA with the same number of base
    pairs. DONs thus have great potential to alleviate oxidative stress caused by
    singlet oxygen in diverse therapeutic settings.</jats:p>
author:
- first_name: Jaime Andres
  full_name: Garcia-Diosa, Jaime Andres
  last_name: Garcia-Diosa
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Garcia-Diosa JA, Grundmeier G, Keller A. Highly Efficient Quenching of Singlet
    Oxygen by DNA Origami Nanostructures. <i>Chemistry – A European Journal</i>. Published
    online 2024. doi:<a href="https://doi.org/10.1002/chem.202402057">10.1002/chem.202402057</a>
  apa: Garcia-Diosa, J. A., Grundmeier, G., &#38; Keller, A. (2024). Highly Efficient
    Quenching of Singlet Oxygen by DNA Origami Nanostructures. <i>Chemistry – A European
    Journal</i>. <a href="https://doi.org/10.1002/chem.202402057">https://doi.org/10.1002/chem.202402057</a>
  bibtex: '@article{Garcia-Diosa_Grundmeier_Keller_2024, title={Highly Efficient Quenching
    of Singlet Oxygen by DNA Origami Nanostructures}, DOI={<a href="https://doi.org/10.1002/chem.202402057">10.1002/chem.202402057</a>},
    journal={Chemistry – A European Journal}, publisher={Wiley}, author={Garcia-Diosa,
    Jaime Andres and Grundmeier, Guido and Keller, Adrian}, year={2024} }'
  chicago: Garcia-Diosa, Jaime Andres, Guido Grundmeier, and Adrian Keller. “Highly
    Efficient Quenching of Singlet Oxygen by DNA Origami Nanostructures.” <i>Chemistry
    – A European Journal</i>, 2024. <a href="https://doi.org/10.1002/chem.202402057">https://doi.org/10.1002/chem.202402057</a>.
  ieee: 'J. A. Garcia-Diosa, G. Grundmeier, and A. Keller, “Highly Efficient Quenching
    of Singlet Oxygen by DNA Origami Nanostructures,” <i>Chemistry – A European Journal</i>,
    2024, doi: <a href="https://doi.org/10.1002/chem.202402057">10.1002/chem.202402057</a>.'
  mla: Garcia-Diosa, Jaime Andres, et al. “Highly Efficient Quenching of Singlet Oxygen
    by DNA Origami Nanostructures.” <i>Chemistry – A European Journal</i>, Wiley,
    2024, doi:<a href="https://doi.org/10.1002/chem.202402057">10.1002/chem.202402057</a>.
  short: J.A. Garcia-Diosa, G. Grundmeier, A. Keller, Chemistry – A European Journal
    (2024).
date_created: 2024-06-07T07:53:50Z
date_updated: 2024-06-07T07:54:02Z
department:
- _id: '302'
doi: 10.1002/chem.202402057
language:
- iso: eng
publication: Chemistry – A European Journal
publication_identifier:
  issn:
  - 0947-6539
  - 1521-3765
publication_status: published
publisher: Wiley
status: public
title: Highly Efficient Quenching of Singlet Oxygen by DNA Origami Nanostructures
type: journal_article
user_id: '48864'
year: '2024'
...
---
_id: '55310'
abstract:
- lang: eng
  text: <jats:p>DNA origami nanostructures are promising carries for drug delivery
    applications. However, their limited stability under relevant conditions often
    presents a challenge. Herein, the structural stability of DNA origami nanostructures
    is investigated in a setting compatible with their application in photodynamic
    therapy (PDT). To this end, DNA origami triangles and six‐helix bundles (6HBs)
    are loaded with the clinically tested photosensitizer methylene blue, which upon
    irradiation with red light generates reactive oxygen species (ROS) that attack
    the DNA origami nanostructures. ROS‐induced structural damage is observed to depend
    on the ionic composition of the surrounding medium and becomes more severe at
    low ionic strength. Mg<jats:sup>2+</jats:sup> ions can efficiently protect the
    DNA origami nanostructures from ROS‐induced damage and may even heal some of the
    damage obtained under Mg<jats:sup>2+</jats:sup>‐free conditions when added after
    irradiation. Finally, the employed DNA origami 6HBs are more resistant toward
    ROS‐induced structural damage than the triangles, which is attributed to their
    markedly different mechanical properties. These results thus provide some fundamental
    insights into the stabilizing role of DNA origami superstructure that may guide
    the selection or design of DNA origami nanocarriers with optimized stability for
    their application in PDT.</jats:p>
author:
- first_name: Lukas
  full_name: Rabbe, Lukas
  last_name: Rabbe
- first_name: Jaime Andres
  full_name: Garcia‐Diosa, Jaime Andres
  last_name: Garcia‐Diosa
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Rabbe L, Garcia‐Diosa JA, Grundmeier G, Keller A. Ion‐Dependent Stability of
    DNA Origami Nanostructures in the Presence of Photo‐Generated Reactive Oxygen
    Species. <i>Small Structures</i>. Published online 2024. doi:<a href="https://doi.org/10.1002/sstr.202400094">10.1002/sstr.202400094</a>
  apa: Rabbe, L., Garcia‐Diosa, J. A., Grundmeier, G., &#38; Keller, A. (2024). Ion‐Dependent
    Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated Reactive
    Oxygen Species. <i>Small Structures</i>. <a href="https://doi.org/10.1002/sstr.202400094">https://doi.org/10.1002/sstr.202400094</a>
  bibtex: '@article{Rabbe_Garcia‐Diosa_Grundmeier_Keller_2024, title={Ion‐Dependent
    Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated Reactive
    Oxygen Species}, DOI={<a href="https://doi.org/10.1002/sstr.202400094">10.1002/sstr.202400094</a>},
    journal={Small Structures}, publisher={Wiley}, author={Rabbe, Lukas and Garcia‐Diosa,
    Jaime Andres and Grundmeier, Guido and Keller, Adrian}, year={2024} }'
  chicago: Rabbe, Lukas, Jaime Andres Garcia‐Diosa, Guido Grundmeier, and Adrian Keller.
    “Ion‐Dependent Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated
    Reactive Oxygen Species.” <i>Small Structures</i>, 2024. <a href="https://doi.org/10.1002/sstr.202400094">https://doi.org/10.1002/sstr.202400094</a>.
  ieee: 'L. Rabbe, J. A. Garcia‐Diosa, G. Grundmeier, and A. Keller, “Ion‐Dependent
    Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated Reactive
    Oxygen Species,” <i>Small Structures</i>, 2024, doi: <a href="https://doi.org/10.1002/sstr.202400094">10.1002/sstr.202400094</a>.'
  mla: Rabbe, Lukas, et al. “Ion‐Dependent Stability of DNA Origami Nanostructures
    in the Presence of Photo‐Generated Reactive Oxygen Species.” <i>Small Structures</i>,
    Wiley, 2024, doi:<a href="https://doi.org/10.1002/sstr.202400094">10.1002/sstr.202400094</a>.
  short: L. Rabbe, J.A. Garcia‐Diosa, G. Grundmeier, A. Keller, Small Structures (2024).
date_created: 2024-07-18T09:03:17Z
date_updated: 2024-07-18T09:03:49Z
department:
- _id: '302'
doi: 10.1002/sstr.202400094
language:
- iso: eng
publication: Small Structures
publication_identifier:
  issn:
  - 2688-4062
  - 2688-4062
publication_status: published
publisher: Wiley
status: public
title: Ion‐Dependent Stability of DNA Origami Nanostructures in the Presence of Photo‐Generated
  Reactive Oxygen Species
type: journal_article
user_id: '48864'
year: '2024'
...
---
_id: '58611'
abstract:
- lang: eng
  text: AFM-IR investigation of thin PECVD SiOx films on a polypropylene substrate
    in the surface-sensitive mode
author:
- first_name: Hendrik
  full_name: Müller, Hendrik
  last_name: Müller
- first_name: Hartmut
  full_name: Stadler, Hartmut
  last_name: Stadler
- first_name: Maria Teresa
  full_name: de los Arcos de Pedro, Maria Teresa
  id: '54556'
  last_name: de los Arcos de Pedro
  orcid: '0000-0002-8684-273X '
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
citation:
  ama: Müller H, Stadler H, de los Arcos de Pedro MT, Keller A, Grundmeier G. AFM-IR
    investigation of thin PECVD SiO x films on a polypropylene substrate in the surface-sensitive
    mode. <i>Beilstein Journal of Nanotechnology</i>. 2024;15(1):603–611. doi:<a href="https://doi.org/10.3762/bjnano.15.51">10.3762/bjnano.15.51</a>
  apa: Müller, H., Stadler, H., de los Arcos de Pedro, M. T., Keller, A., &#38; Grundmeier,
    G. (2024). AFM-IR investigation of thin PECVD SiO x films on a polypropylene substrate
    in the surface-sensitive mode. <i>Beilstein Journal of Nanotechnology</i>, <i>15</i>(1),
    603–611. <a href="https://doi.org/10.3762/bjnano.15.51">https://doi.org/10.3762/bjnano.15.51</a>
  bibtex: '@article{Müller_Stadler_de los Arcos de Pedro_Keller_Grundmeier_2024, title={AFM-IR
    investigation of thin PECVD SiO x films on a polypropylene substrate in the surface-sensitive
    mode}, volume={15}, DOI={<a href="https://doi.org/10.3762/bjnano.15.51">10.3762/bjnano.15.51</a>},
    number={1}, journal={Beilstein Journal of Nanotechnology}, author={Müller, Hendrik
    and Stadler, Hartmut and de los Arcos de Pedro, Maria Teresa and Keller, Adrian
    and Grundmeier, Guido}, year={2024}, pages={603–611} }'
  chicago: 'Müller, Hendrik, Hartmut Stadler, Maria Teresa de los Arcos de Pedro,
    Adrian Keller, and Guido Grundmeier. “AFM-IR Investigation of Thin PECVD SiO x
    Films on a Polypropylene Substrate in the Surface-Sensitive Mode.” <i>Beilstein
    Journal of Nanotechnology</i> 15, no. 1 (2024): 603–611. <a href="https://doi.org/10.3762/bjnano.15.51">https://doi.org/10.3762/bjnano.15.51</a>.'
  ieee: 'H. Müller, H. Stadler, M. T. de los Arcos de Pedro, A. Keller, and G. Grundmeier,
    “AFM-IR investigation of thin PECVD SiO x films on a polypropylene substrate in
    the surface-sensitive mode,” <i>Beilstein Journal of Nanotechnology</i>, vol.
    15, no. 1, pp. 603–611, 2024, doi: <a href="https://doi.org/10.3762/bjnano.15.51">10.3762/bjnano.15.51</a>.'
  mla: Müller, Hendrik, et al. “AFM-IR Investigation of Thin PECVD SiO x Films on
    a Polypropylene Substrate in the Surface-Sensitive Mode.” <i>Beilstein Journal
    of Nanotechnology</i>, vol. 15, no. 1, 2024, pp. 603–611, doi:<a href="https://doi.org/10.3762/bjnano.15.51">10.3762/bjnano.15.51</a>.
  short: H. Müller, H. Stadler, M.T. de los Arcos de Pedro, A. Keller, G. Grundmeier,
    Beilstein Journal of Nanotechnology 15 (2024) 603–611.
date_created: 2025-02-12T14:48:49Z
date_updated: 2025-02-12T14:56:14Z
department:
- _id: '302'
doi: 10.3762/bjnano.15.51
intvolume: '        15'
issue: '1'
language:
- iso: eng
page: 603–611
publication: Beilstein Journal of Nanotechnology
publication_identifier:
  issn:
  - 2190-4286
status: public
title: AFM-IR investigation of thin PECVD SiO x films on a polypropylene substrate
  in the surface-sensitive mode
type: journal_article
user_id: '54556'
volume: 15
year: '2024'
...