[{"doi":"10.1002/adsc.202400511","main_file_link":[{"url":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202400511","open_access":"1"}],"oa":"1","date_updated":"2025-04-22T06:11:59Z","volume":366,"author":[{"first_name":"Axel","last_name":"Hoppe","id":"62844","full_name":"Hoppe, Axel"},{"first_name":"Arne J.","full_name":"Stepen, Arne J.","last_name":"Stepen"},{"full_name":"Köring, Laura","last_name":"Köring","first_name":"Laura"},{"first_name":"Jan","last_name":"Paradies","orcid":"0000-0002-3698-668X","id":"53339","full_name":"Paradies, Jan"}],"intvolume":"       366","page":"2933-2938","citation":{"chicago":"Hoppe, Axel, Arne J. Stepen, Laura Köring, and Jan Paradies. “Tris(Pentafluorophenyl)Borane‐Catalyzed Functionalization of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i> 366, no. 13 (2024): 2933–38. <a href=\"https://doi.org/10.1002/adsc.202400511\">https://doi.org/10.1002/adsc.202400511</a>.","ieee":"A. Hoppe, A. J. Stepen, L. Köring, and J. Paradies, “Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds,” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 366, no. 13, pp. 2933–2938, 2024, doi: <a href=\"https://doi.org/10.1002/adsc.202400511\">10.1002/adsc.202400511</a>.","ama":"Hoppe A, Stepen AJ, Köring L, Paradies J. Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>. 2024;366(13):2933-2938. doi:<a href=\"https://doi.org/10.1002/adsc.202400511\">10.1002/adsc.202400511</a>","short":"A. Hoppe, A.J. Stepen, L. Köring, J. Paradies, Advanced Synthesis &#38;amp; Catalysis 366 (2024) 2933–2938.","mla":"Hoppe, Axel, et al. “Tris(Pentafluorophenyl)Borane‐Catalyzed Functionalization of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 366, no. 13, Wiley, 2024, pp. 2933–38, doi:<a href=\"https://doi.org/10.1002/adsc.202400511\">10.1002/adsc.202400511</a>.","bibtex":"@article{Hoppe_Stepen_Köring_Paradies_2024, title={Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds}, volume={366}, DOI={<a href=\"https://doi.org/10.1002/adsc.202400511\">10.1002/adsc.202400511</a>}, number={13}, journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley}, author={Hoppe, Axel and Stepen, Arne J. and Köring, Laura and Paradies, Jan}, year={2024}, pages={2933–2938} }","apa":"Hoppe, A., Stepen, A. J., Köring, L., &#38; Paradies, J. (2024). Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>, <i>366</i>(13), 2933–2938. <a href=\"https://doi.org/10.1002/adsc.202400511\">https://doi.org/10.1002/adsc.202400511</a>"},"publication_identifier":{"issn":["1615-4150","1615-4169"]},"publication_status":"published","_id":"59616","department":[{"_id":"389"}],"user_id":"62844","status":"public","type":"journal_article","title":"Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds","publisher":"Wiley","date_created":"2025-04-22T05:59:08Z","year":"2024","quality_controlled":"1","issue":"13","keyword":["fluoride","bond activation","borane","Lewis acid","C-C bond formation"],"language":[{"iso":"eng"}],"abstract":[{"text":"<jats:title>Abstract</jats:title><jats:p>The activation of C(<jats:italic>sp</jats:italic><jats:sup>3</jats:sup>)−F bonds by the commercially available catalyst B(C<jats:sub>6</jats:sub>F<jats:sub>5</jats:sub>)<jats:sub>3</jats:sub> is reported and applied in reactions with arenes, allylic, vinylic and acetylenic silanes, and olefins to achieve a variety of C−C bond formations (45 examples).</jats:p>","lang":"eng"}],"publication":"Advanced Synthesis &amp; Catalysis"},{"language":[{"iso":"eng"}],"article_number":"768","user_id":"62844","department":[{"_id":"311"}],"_id":"59617","status":"public","abstract":[{"lang":"eng","text":"<jats:p>There is an increasing interest in sensing applications for a variety of analytes in aqueous environments, as conventional methods do not work reliably under humid conditions or they require complex equipment with experienced operators. Hydrogel sensors are easy to fabricate, are incredibly sensitive, and have broad dynamic ranges. Experiments on their robustness, reliability, and reusability have indicated the possible long-term applications of these systems in a variety of fields, including disease diagnosis, detection of pharmaceuticals, and in environmental testing. It is possible to produce hydrogels, which, upon sensing a specific analyte, can adsorb it onto their 3D-structure and can therefore be used to remove them from a given environment. High specificity can be obtained by using molecularly imprinted polymers. Typical detection principles involve optical methods including fluorescence and chemiluminescence, and volume changes in colloidal photonic crystals, as well as electrochemical methods. Here, we explore the current research utilizing hydrogel-based sensors in three main areas: (1) biomedical applications, (2) for detecting and quantifying pharmaceuticals of interest, and (3) detecting and quantifying environmental contaminants in aqueous environments.</jats:p>"}],"type":"journal_article","publication":"Gels","main_file_link":[{"open_access":"1","url":"https://www.mdpi.com/2310-2861/8/12/768"}],"doi":"10.3390/gels8120768","title":"Hydrogel-Based Biosensors","author":[{"first_name":"Katharina","last_name":"Völlmecke","full_name":"Völlmecke, Katharina"},{"first_name":"Rowshon","full_name":"Afroz, Rowshon","last_name":"Afroz"},{"first_name":"Sascha","full_name":"Bierbach, Sascha","last_name":"Bierbach"},{"last_name":"Brenker","full_name":"Brenker, Lee Josephine","first_name":"Lee Josephine"},{"first_name":"Sebastian","last_name":"Frücht","full_name":"Frücht, Sebastian"},{"full_name":"Glass, Alexandra","last_name":"Glass","first_name":"Alexandra"},{"first_name":"Ryland","full_name":"Giebelhaus, Ryland","last_name":"Giebelhaus"},{"first_name":"Axel","last_name":"Hoppe","full_name":"Hoppe, Axel","id":"62844"},{"full_name":"Kanemaru, Karen","last_name":"Kanemaru","first_name":"Karen"},{"last_name":"Lazarek","full_name":"Lazarek, Michal","first_name":"Michal"},{"full_name":"Rabbe, Lukas","last_name":"Rabbe","first_name":"Lukas"},{"first_name":"Longfei","last_name":"Song","full_name":"Song, Longfei"},{"first_name":"Andrea","last_name":"Velasco Suarez","full_name":"Velasco Suarez, Andrea"},{"first_name":"Shuang","full_name":"Wu, Shuang","last_name":"Wu"},{"full_name":"Serpe, Michael","last_name":"Serpe","first_name":"Michael"},{"first_name":"Dirk","id":"287","full_name":"Kuckling, Dirk","last_name":"Kuckling"}],"date_created":"2025-04-22T05:59:29Z","volume":8,"publisher":"MDPI AG","oa":"1","date_updated":"2025-04-22T06:12:07Z","citation":{"ama":"Völlmecke K, Afroz R, Bierbach S, et al. Hydrogel-Based Biosensors. <i>Gels</i>. 2022;8(12). doi:<a href=\"https://doi.org/10.3390/gels8120768\">10.3390/gels8120768</a>","chicago":"Völlmecke, Katharina, Rowshon Afroz, Sascha Bierbach, Lee Josephine Brenker, Sebastian Frücht, Alexandra Glass, Ryland Giebelhaus, et al. “Hydrogel-Based Biosensors.” <i>Gels</i> 8, no. 12 (2022). <a href=\"https://doi.org/10.3390/gels8120768\">https://doi.org/10.3390/gels8120768</a>.","ieee":"K. Völlmecke <i>et al.</i>, “Hydrogel-Based Biosensors,” <i>Gels</i>, vol. 8, no. 12, Art. no. 768, 2022, doi: <a href=\"https://doi.org/10.3390/gels8120768\">10.3390/gels8120768</a>.","apa":"Völlmecke, K., Afroz, R., Bierbach, S., Brenker, L. J., Frücht, S., Glass, A., Giebelhaus, R., Hoppe, A., Kanemaru, K., Lazarek, M., Rabbe, L., Song, L., Velasco Suarez, A., Wu, S., Serpe, M., &#38; Kuckling, D. (2022). Hydrogel-Based Biosensors. <i>Gels</i>, <i>8</i>(12), Article 768. <a href=\"https://doi.org/10.3390/gels8120768\">https://doi.org/10.3390/gels8120768</a>","mla":"Völlmecke, Katharina, et al. “Hydrogel-Based Biosensors.” <i>Gels</i>, vol. 8, no. 12, 768, MDPI AG, 2022, doi:<a href=\"https://doi.org/10.3390/gels8120768\">10.3390/gels8120768</a>.","short":"K. Völlmecke, R. Afroz, S. Bierbach, L.J. Brenker, S. Frücht, A. Glass, R. Giebelhaus, A. Hoppe, K. Kanemaru, M. Lazarek, L. Rabbe, L. Song, A. Velasco Suarez, S. Wu, M. Serpe, D. Kuckling, Gels 8 (2022).","bibtex":"@article{Völlmecke_Afroz_Bierbach_Brenker_Frücht_Glass_Giebelhaus_Hoppe_Kanemaru_Lazarek_et al._2022, title={Hydrogel-Based Biosensors}, volume={8}, DOI={<a href=\"https://doi.org/10.3390/gels8120768\">10.3390/gels8120768</a>}, number={12768}, journal={Gels}, publisher={MDPI AG}, author={Völlmecke, Katharina and Afroz, Rowshon and Bierbach, Sascha and Brenker, Lee Josephine and Frücht, Sebastian and Glass, Alexandra and Giebelhaus, Ryland and Hoppe, Axel and Kanemaru, Karen and Lazarek, Michal and et al.}, year={2022} }"},"intvolume":"         8","year":"2022","issue":"12","publication_status":"published","publication_identifier":{"issn":["2310-2861"]},"quality_controlled":"1"},{"publication_identifier":{"issn":["1615-4150","1615-4169"]},"publication_status":"published","intvolume":"       364","page":"3143-3148","citation":{"apa":"Sieland, B., Hoppe, A., Stepen, A. J., &#38; Paradies, J. (2022). Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis. <i>Advanced Synthesis &#38;amp; Catalysis</i>, <i>364</i>(18), 3143–3148. <a href=\"https://doi.org/10.1002/adsc.202200525\">https://doi.org/10.1002/adsc.202200525</a>","bibtex":"@article{Sieland_Hoppe_Stepen_Paradies_2022, title={Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis}, volume={364}, DOI={<a href=\"https://doi.org/10.1002/adsc.202200525\">10.1002/adsc.202200525</a>}, number={18}, journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley}, author={Sieland, Benedikt and Hoppe, Axel and Stepen, Arne J. and Paradies, Jan}, year={2022}, pages={3143–3148} }","mla":"Sieland, Benedikt, et al. “Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 364, no. 18, Wiley, 2022, pp. 3143–48, doi:<a href=\"https://doi.org/10.1002/adsc.202200525\">10.1002/adsc.202200525</a>.","short":"B. Sieland, A. Hoppe, A.J. Stepen, J. Paradies, Advanced Synthesis &#38;amp; Catalysis 364 (2022) 3143–3148.","chicago":"Sieland, Benedikt, Axel Hoppe, Arne J. Stepen, and Jan Paradies. “Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.” <i>Advanced Synthesis &#38;amp; Catalysis</i> 364, no. 18 (2022): 3143–48. <a href=\"https://doi.org/10.1002/adsc.202200525\">https://doi.org/10.1002/adsc.202200525</a>.","ieee":"B. Sieland, A. Hoppe, A. J. Stepen, and J. Paradies, “Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis,” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 364, no. 18, pp. 3143–3148, 2022, doi: <a href=\"https://doi.org/10.1002/adsc.202200525\">10.1002/adsc.202200525</a>.","ama":"Sieland B, Hoppe A, Stepen AJ, Paradies J. Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis. <i>Advanced Synthesis &#38;amp; Catalysis</i>. 2022;364(18):3143-3148. doi:<a href=\"https://doi.org/10.1002/adsc.202200525\">10.1002/adsc.202200525</a>"},"volume":364,"author":[{"last_name":"Sieland","full_name":"Sieland, Benedikt","first_name":"Benedikt"},{"last_name":"Hoppe","full_name":"Hoppe, Axel","id":"62844","first_name":"Axel"},{"first_name":"Arne J.","last_name":"Stepen","full_name":"Stepen, Arne J."},{"first_name":"Jan","full_name":"Paradies, Jan","id":"53339","orcid":"0000-0002-3698-668X","last_name":"Paradies"}],"oa":"1","date_updated":"2025-04-22T06:12:05Z","doi":"10.1002/adsc.202200525","main_file_link":[{"url":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202200525","open_access":"1"}],"type":"journal_article","status":"public","department":[{"_id":"389"}],"user_id":"62844","_id":"59619","issue":"18","quality_controlled":"1","year":"2022","date_created":"2025-04-22T06:01:56Z","publisher":"Wiley","title":"Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis","publication":"Advanced Synthesis &amp; Catalysis","abstract":[{"text":"<jats:title>Abstract</jats:title><jats:p>A frustrated Lewis pair‐catalyzed hydroboration of aromatic and aliphatic nitriles was developed. The catalyst provides the primary amines in high yields of 77–99% with catalyst loading as low as 2 mol%. The reaction displays high functional group tolerance towards esters, amides, nitro groups and aliphatic halides. The addition of the diborylated amines to ethyl 3‐phenylpropiolate proceeds with Z‐selectivity with d.r. of &gt;99:1 in 77–90% yield over two steps. The reaction mechanism was investigated by control and computational experiments.</jats:p><jats:p><jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" mimetype=\"image/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic/adsc202200525-toc-0001-m.png\"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text>\r\n</jats:p>","lang":"eng"}],"language":[{"iso":"eng"}],"keyword":["hydroboration","nitrile","amine","frustrated Lewis pair","density functional theory"]},{"type":"journal_article","status":"public","department":[{"_id":"311"}],"user_id":"62844","_id":"59620","article_type":"original","publication_identifier":{"issn":["2637-6105","2637-6105"]},"publication_status":"published","intvolume":"         3","page":"3831-3842","citation":{"chicago":"Rust, Tarik, Dimitri Jung, Axel Hoppe, Timo Schoppa, Klaus Langer, and Dirk Kuckling. “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery.” <i>ACS Applied Polymer Materials</i> 3, no. 8 (2021): 3831–42. <a href=\"https://doi.org/10.1021/acsapm.1c00411\">https://doi.org/10.1021/acsapm.1c00411</a>.","ieee":"T. Rust, D. Jung, A. Hoppe, T. Schoppa, K. Langer, and D. Kuckling, “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery,” <i>ACS Applied Polymer Materials</i>, vol. 3, no. 8, pp. 3831–3842, 2021, doi: <a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>.","ama":"Rust T, Jung D, Hoppe A, Schoppa T, Langer K, Kuckling D. Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery. <i>ACS Applied Polymer Materials</i>. 2021;3(8):3831-3842. doi:<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>","apa":"Rust, T., Jung, D., Hoppe, A., Schoppa, T., Langer, K., &#38; Kuckling, D. (2021). Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery. <i>ACS Applied Polymer Materials</i>, <i>3</i>(8), 3831–3842. <a href=\"https://doi.org/10.1021/acsapm.1c00411\">https://doi.org/10.1021/acsapm.1c00411</a>","bibtex":"@article{Rust_Jung_Hoppe_Schoppa_Langer_Kuckling_2021, title={Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery}, volume={3}, DOI={<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>}, number={8}, journal={ACS Applied Polymer Materials}, publisher={American Chemical Society (ACS)}, author={Rust, Tarik and Jung, Dimitri and Hoppe, Axel and Schoppa, Timo and Langer, Klaus and Kuckling, Dirk}, year={2021}, pages={3831–3842} }","mla":"Rust, Tarik, et al. “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery.” <i>ACS Applied Polymer Materials</i>, vol. 3, no. 8, American Chemical Society (ACS), 2021, pp. 3831–42, doi:<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>.","short":"T. Rust, D. Jung, A. Hoppe, T. Schoppa, K. Langer, D. Kuckling, ACS Applied Polymer Materials 3 (2021) 3831–3842."},"volume":3,"author":[{"first_name":"Tarik","full_name":"Rust, Tarik","last_name":"Rust"},{"first_name":"Dimitri","last_name":"Jung","full_name":"Jung, Dimitri"},{"first_name":"Axel","id":"62844","full_name":"Hoppe, Axel","last_name":"Hoppe"},{"first_name":"Timo","last_name":"Schoppa","full_name":"Schoppa, Timo"},{"first_name":"Klaus","full_name":"Langer, Klaus","last_name":"Langer"},{"full_name":"Kuckling, Dirk","id":"287","last_name":"Kuckling","first_name":"Dirk"}],"date_updated":"2025-04-22T06:12:02Z","doi":"10.1021/acsapm.1c00411","main_file_link":[{"url":"https://pubs.acs.org/doi/10.1021/acsapm.1c00411?ref=PDF"}],"publication":"ACS Applied Polymer Materials","language":[{"iso":"eng"}],"keyword":["backbone-degradable","light-responsive","redox-responsive","drug delivery","nanoparticles"],"issue":"8","quality_controlled":"1","year":"2021","date_created":"2025-04-22T06:02:11Z","publisher":"American Chemical Society (ACS)","title":"Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery"}]