--- _id: '27575' abstract: - lang: eng text: There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androgen receptor gene (AR), a variable number of CAG repeats. Moreover, there is preliminary evidence that the relationship between testosterone, CAG repeat length, and the severity of depressive symptoms may differ between subclinical and overt depression, but this has neither been studied in a clinical sample of adolescents with depression nor compared between subclinical and overt depression in an adequately powered study. To investigate the relationship between free testosterone, CAG repeat length of the AR, depression status (subclinical vs. overt), and the severity of depressive symptoms, 118 boys treated as in- or daycare patients at a single psychiatric hospital were studied. Of these, 73 boys had at least mild depressive symptoms according to the Beck Depression Inventory-II (BDI-II > 13). Higher-order moderation analysis in the multiple regression framework revealed a constant relationship between free testosterone and depression severity irrespective of the number of CAG repeats in adolescents with a BDI-II score ≤ 13. In adolescents with a BDI-II score > 13, however, there was a significant negative relationship between free testosterone and BDI-II score in patients with <19 CAG repeats and a significant positive relationship regarding free testosterone and BDI-II score in those with more than 28 CAG repeats, even when considering important covariates. These results suggest that the effects of testosterone on mood in male adolescents with depression depend on the genetic make-up of the AR as well as on depression status. This complex relationship should be considered by future studies addressing mental health issues against an endocrine background and may, moreover, contribute to tailored treatment concepts in psychiatric medicine, especially in adults. author: - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Judith full_name: Bühlmeier, Judith last_name: Bühlmeier - first_name: Paul-Martin full_name: Holterhus, Paul-Martin last_name: Holterhus - first_name: Alexandra full_name: Kulle, Alexandra last_name: Kulle - first_name: Cordula full_name: Kiewert, Cordula last_name: Kiewert - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann citation: ama: 'Hirtz R, Libuda L, Hinney A, et al. Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity. Frontiers in Psychiatry. Published online 2021. doi:10.3389/fpsyt.2021.732759' apa: 'Hirtz, R., Libuda, L., Hinney, A., Föcker, M., Bühlmeier, J., Holterhus, P.-M., Kulle, A., Kiewert, C., Hebebrand, J., & Grasemann, C. (2021). Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity. Frontiers in Psychiatry. https://doi.org/10.3389/fpsyt.2021.732759' bibtex: '@article{Hirtz_Libuda_Hinney_Föcker_Bühlmeier_Holterhus_Kulle_Kiewert_Hebebrand_Grasemann_2021, title={Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity}, DOI={10.3389/fpsyt.2021.732759}, journal={Frontiers in Psychiatry}, author={Hirtz, Raphael and Libuda, Lars and Hinney, Anke and Föcker, Manuel and Bühlmeier, Judith and Holterhus, Paul-Martin and Kulle, Alexandra and Kiewert, Cordula and Hebebrand, Johannes and Grasemann, Corinna}, year={2021} }' chicago: 'Hirtz, Raphael, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Johannes Hebebrand, and Corinna Grasemann. “Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity.” Frontiers in Psychiatry, 2021. https://doi.org/10.3389/fpsyt.2021.732759.' ieee: 'R. Hirtz et al., “Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity,” Frontiers in Psychiatry, 2021, doi: 10.3389/fpsyt.2021.732759.' mla: 'Hirtz, Raphael, et al. “Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity.” Frontiers in Psychiatry, 2021, doi:10.3389/fpsyt.2021.732759.' short: R. Hirtz, L. Libuda, A. Hinney, M. Föcker, J. Bühlmeier, P.-M. Holterhus, A. Kulle, C. Kiewert, J. Hebebrand, C. Grasemann, Frontiers in Psychiatry (2021). date_created: 2021-11-18T19:57:38Z date_updated: 2022-09-15T09:40:45Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.3389/fpsyt.2021.732759 extern: '1' language: - iso: eng publication: Frontiers in Psychiatry publication_identifier: issn: - 1664-0640 publication_status: published status: public title: 'Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity' type: journal_article user_id: '89838' year: '2021' ... --- _id: '27571' abstract: - lang: eng text: '(1) Background: Evidence has accumulated that patients with anorexia nervosa (AN) are at higher risk for vitamin D deficiency than healthy controls. In epidemiologic studies, low 25(OH) vitamin D (25(OH)D) levels were associated with depression. This study analyzed the relationship between 25(OH)D serum levels in adolescent patients and AN and depressive symptoms over the course of treatment. (2) Methods: 25(OH)D levels and depressive symptoms were analyzed in 93 adolescent (in-)patients with AN from the Anorexia Nervosa Day patient versus Inpatient (ANDI) multicenter trial at clinic admission, discharge, and 1 year follow up. Mixed regression models were used to analyze the relationship between 25(OH)D levels and depressive symptoms assessed by the Beck Depression Inventory (BDI-II). (3) Results: Although mean 25(OH)D levels constantly remained in recommended ranges (≥50 nmol/L) during AN treatment, levels decreased from (in)patient admission to 1 year follow up. Levels of 25(OH)D were neither cross-sectionally, prospectively, nor longitudinally associated with the BDI-II score. (4) Conclusions: This study did not confirm that 25(OH)D levels are associated with depressive symptoms in patients with AN. However, increasing risks of vitamin D deficiency over the course of AN treatment indicate that clinicians should monitor 25(OH)D levels.' article_number: '2356' author: - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Nina full_name: Timmesfeld, Nina last_name: Timmesfeld - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Denise full_name: Zwanziger, Denise last_name: Zwanziger - first_name: Dagmar full_name: Führer, Dagmar last_name: Führer - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann - first_name: Stefan full_name: Ehrlich, Stefan last_name: Ehrlich - first_name: Karin full_name: Egberts, Karin last_name: Egberts - first_name: Christian full_name: Fleischhaker, Christian last_name: Fleischhaker - first_name: Christoph full_name: Wewetzer, Christoph last_name: Wewetzer - first_name: Ida full_name: Wessing, Ida last_name: Wessing - first_name: Jochen full_name: Seitz, Jochen last_name: Seitz - first_name: Beate full_name: Herpertz-Dahlmann, Beate last_name: Herpertz-Dahlmann - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: 'Föcker M, Timmesfeld N, Bühlmeier J, et al. Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms. Nutrients. Published online 2021. doi:10.3390/nu13072356' apa: 'Föcker, M., Timmesfeld, N., Bühlmeier, J., Zwanziger, D., Führer, D., Grasemann, C., Ehrlich, S., Egberts, K., Fleischhaker, C., Wewetzer, C., Wessing, I., Seitz, J., Herpertz-Dahlmann, B., Hebebrand, J., & Libuda, L. (2021). Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms. Nutrients, Article 2356. https://doi.org/10.3390/nu13072356' bibtex: '@article{Föcker_Timmesfeld_Bühlmeier_Zwanziger_Führer_Grasemann_Ehrlich_Egberts_Fleischhaker_Wewetzer_et al._2021, title={Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms}, DOI={10.3390/nu13072356}, number={2356}, journal={Nutrients}, author={Föcker, Manuel and Timmesfeld, Nina and Bühlmeier, Judith and Zwanziger, Denise and Führer, Dagmar and Grasemann, Corinna and Ehrlich, Stefan and Egberts, Karin and Fleischhaker, Christian and Wewetzer, Christoph and et al.}, year={2021} }' chicago: 'Föcker, Manuel, Nina Timmesfeld, Judith Bühlmeier, Denise Zwanziger, Dagmar Führer, Corinna Grasemann, Stefan Ehrlich, et al. “Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms.” Nutrients, 2021. https://doi.org/10.3390/nu13072356.' ieee: 'M. Föcker et al., “Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms,” Nutrients, Art. no. 2356, 2021, doi: 10.3390/nu13072356.' mla: 'Föcker, Manuel, et al. “Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms.” Nutrients, 2356, 2021, doi:10.3390/nu13072356.' short: M. Föcker, N. Timmesfeld, J. Bühlmeier, D. Zwanziger, D. Führer, C. Grasemann, S. Ehrlich, K. Egberts, C. Fleischhaker, C. Wewetzer, I. Wessing, J. Seitz, B. Herpertz-Dahlmann, J. Hebebrand, L. Libuda, Nutrients (2021). date_created: 2021-11-18T19:23:23Z date_updated: 2022-09-15T09:42:11Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.3390/nu13072356 extern: '1' language: - iso: eng publication: Nutrients publication_identifier: issn: - 2072-6643 publication_status: published status: public title: 'Vitamin D Level Trajectories of Adolescent Patients with Anorexia Nervosa at Inpatient Admission, during Treatment, and at One Year Follow Up: Association with Depressive Symptoms' type: journal_article user_id: '89838' year: '2021' ... --- _id: '26525' author: - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Susanne full_name: Tan, Susanne last_name: Tan - first_name: Martin full_name: Wabitsch, Martin last_name: Wabitsch - first_name: Urban full_name: Wiesing, Urban last_name: Wiesing - first_name: Nikolaus full_name: Barth, Nikolaus last_name: Barth - first_name: Christine full_name: Ludwig, Christine last_name: Ludwig - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Gabriella full_name: Milos, Gabriella last_name: Milos - first_name: Anke full_name: Hinney, Anke last_name: Hinney citation: ama: 'Hebebrand J, Antel J, Tan S, et al. Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. Published online 2021:1-5. doi:10.1024/1422-4917/a000775' apa: 'Hebebrand, J., Antel, J., Tan, S., Wabitsch, M., Wiesing, U., Barth, N., Ludwig, C., Bühlmeier, J., Libuda, L., Milos, G., & Hinney, A. (2021). Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 1–5. https://doi.org/10.1024/1422-4917/a000775' bibtex: '@article{Hebebrand_Antel_Tan_Wabitsch_Wiesing_Barth_Ludwig_Bühlmeier_Libuda_Milos_et al._2021, title={Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten}, DOI={10.1024/1422-4917/a000775}, journal={Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie}, author={Hebebrand, Johannes and Antel, Jochen and Tan, Susanne and Wabitsch, Martin and Wiesing, Urban and Barth, Nikolaus and Ludwig, Christine and Bühlmeier, Judith and Libuda, Lars and Milos, Gabriella and et al.}, year={2021}, pages={1–5} }' chicago: 'Hebebrand, Johannes, Jochen Antel, Susanne Tan, Martin Wabitsch, Urban Wiesing, Nikolaus Barth, Christine Ludwig, et al. “Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten.” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 2021, 1–5. https://doi.org/10.1024/1422-4917/a000775.' ieee: 'J. Hebebrand et al., “Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten,” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, pp. 1–5, 2021, doi: 10.1024/1422-4917/a000775.' mla: 'Hebebrand, Johannes, et al. “Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit                    rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive                    Effekte auf Stimmung, Kognition und Verhalten.” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 2021, pp. 1–5, doi:10.1024/1422-4917/a000775.' short: J. Hebebrand, J. Antel, S. Tan, M. Wabitsch, U. Wiesing, N. Barth, C. Ludwig, J. Bühlmeier, L. Libuda, G. Milos, A. Hinney, Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie (2021) 1–5. date_created: 2021-10-19T09:55:10Z date_updated: 2022-09-15T09:50:49Z department: - _id: '35' - _id: '22' doi: 10.1024/1422-4917/a000775 extern: '1' language: - iso: ger page: 1-5 publication: Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie publication_identifier: issn: - 1422-4917 - 1664-2880 publication_status: published status: public title: 'Kurzzeitige Behandlung von Patient_innen mit Anorexia nervosa mit rekombinant hergestelltem Human-Leptin (Metreleptin): Rasch einsetzende positive Effekte auf Stimmung, Kognition und Verhalten' type: journal_article user_id: '89838' year: '2021' ... --- _id: '35303' abstract: - lang: eng text: "Abstract\r\n Purpose\r\n \ Studies about effects of lunch dietary Glycemic Index (GI) on cognition of schoolchildren are scarce. Our previous CogniDo GI study found no changes of cognition in the early postprandial phase after consumption of two rice types with medium vs. high dietary GI for lunch (i.e., 45 min after starting lunch). This study investigated whether the dietary GI of lunch has an impact on cognition of schoolchildren in the late postprandial phase, 90 min after lunch.\r\n \r\n Methods\r\n \ A randomized, 2 × 2 crossover intervention study was conducted at a comprehensive school with 5th and 6th grade students. Participants (n = 212) were randomly assigned to either sequence 1 or 2. In the first period, participants of sequence 1 received a dish with high GI rice (GI: 79), those of sequence 2 with medium GI rice (GI: 64)—in the second period, 1 week later, vice versa. Computer-based cognitive testing was performed 90 min after lunch examining tonic alertness, visual search and task switching, and working memory. Treatment effects and treatment effects adjusted for estimated lunch glycemic load (GL) were analyzed using a linear mixed model.\r\n \r\n Results\r\n \ The selected cognitive parameters were not affected by the GI of lunch 90 min after lunch, neither after intention-to-treat nor in the per-protocol analysis. Adjustment for GL also did not change results.\r\n \ \r\n Conclusion\r\n \ The present study revealed no notable differences after the consumption of two rice types with medium vs. high dietary GI for lunch in children’s cognitive function in the late postprandial phase, 90 min after lunch.\r\n \ \r\n Clinical trial registration\r\n German Clinical Trials Register (DRKS00013597); date of registration: 16/04/2018, retrospectively registered.\r\n \ " author: - first_name: Alina full_name: Drozdowska, Alina last_name: Drozdowska - first_name: Kathrin full_name: Sinningen, Kathrin last_name: Sinningen - first_name: Michael full_name: Falkenstein, Michael last_name: Falkenstein - first_name: Henrik full_name: Rudolf, Henrik last_name: Rudolf - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Thomas full_name: Lücke, Thomas last_name: Lücke - first_name: Mathilde full_name: Kersting, Mathilde last_name: Kersting citation: ama: 'Drozdowska A, Sinningen K, Falkenstein M, et al. Impact of lunch with carbohydrates differing in glycemic index on children’s cognitive functioning in the late postprandial phase: a randomized crossover study. European Journal of Nutrition. 2021;61(3):1637-1647. doi:10.1007/s00394-021-02766-y' apa: 'Drozdowska, A., Sinningen, K., Falkenstein, M., Rudolf, H., Libuda, L., Buyken, A., Lücke, T., & Kersting, M. (2021). Impact of lunch with carbohydrates differing in glycemic index on children’s cognitive functioning in the late postprandial phase: a randomized crossover study. European Journal of Nutrition, 61(3), 1637–1647. https://doi.org/10.1007/s00394-021-02766-y' bibtex: '@article{Drozdowska_Sinningen_Falkenstein_Rudolf_Libuda_Buyken_Lücke_Kersting_2021, title={Impact of lunch with carbohydrates differing in glycemic index on children’s cognitive functioning in the late postprandial phase: a randomized crossover study}, volume={61}, DOI={10.1007/s00394-021-02766-y}, number={3}, journal={European Journal of Nutrition}, publisher={Springer Science and Business Media LLC}, author={Drozdowska, Alina and Sinningen, Kathrin and Falkenstein, Michael and Rudolf, Henrik and Libuda, Lars and Buyken, Anette and Lücke, Thomas and Kersting, Mathilde}, year={2021}, pages={1637–1647} }' chicago: 'Drozdowska, Alina, Kathrin Sinningen, Michael Falkenstein, Henrik Rudolf, Lars Libuda, Anette Buyken, Thomas Lücke, and Mathilde Kersting. “Impact of Lunch with Carbohydrates Differing in Glycemic Index on Children’s Cognitive Functioning in the Late Postprandial Phase: A Randomized Crossover Study.” European Journal of Nutrition 61, no. 3 (2021): 1637–47. https://doi.org/10.1007/s00394-021-02766-y.' ieee: 'A. Drozdowska et al., “Impact of lunch with carbohydrates differing in glycemic index on children’s cognitive functioning in the late postprandial phase: a randomized crossover study,” European Journal of Nutrition, vol. 61, no. 3, pp. 1637–1647, 2021, doi: 10.1007/s00394-021-02766-y.' mla: 'Drozdowska, Alina, et al. “Impact of Lunch with Carbohydrates Differing in Glycemic Index on Children’s Cognitive Functioning in the Late Postprandial Phase: A Randomized Crossover Study.” European Journal of Nutrition, vol. 61, no. 3, Springer Science and Business Media LLC, 2021, pp. 1637–47, doi:10.1007/s00394-021-02766-y.' short: A. Drozdowska, K. Sinningen, M. Falkenstein, H. Rudolf, L. Libuda, A. Buyken, T. Lücke, M. Kersting, European Journal of Nutrition 61 (2021) 1637–1647. date_created: 2023-01-05T14:49:10Z date_updated: 2023-01-05T16:47:16Z department: - _id: '35' - _id: '17' - _id: '22' - _id: '571' - _id: '395' doi: 10.1007/s00394-021-02766-y intvolume: ' 61' issue: '3' keyword: - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng page: 1637-1647 publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Impact of lunch with carbohydrates differing in glycemic index on children''s cognitive functioning in the late postprandial phase: a randomized crossover study' type: journal_article user_id: '61597' volume: 61 year: '2021' ... --- _id: '33986' abstract: - lang: eng text: ' Zusammenfassung. Genetische Varianten beeinflussen die Gewichtsregulation und die Entwicklung von Essstörungen. Zunächst haben familienbasierte, sogenannte formalgenetische Studien den erblichen Anteil an der Gewichtsregulation und an der Ätiologie von Essstörungen beleuchtet. In einer Vielzahl von Studien zeigten sich sowohl für die Varianz des Körpergewichts als auch für die Entstehung von Essstörungen Erblichkeitsschätzer (Heritabilitätsraten) von über 50 %. Mit diesem Wissen begab man sich in den 90er-Jahren des letzten Jahrhunderts auf die Suche nach den zugrundeliegenden Genen (genauer: genetischen Varianten), die das Körpergewicht, das Essverhalten oder beide Phänotypen auf Grundlage geteilter Mechanismen beeinflussen. Zunächst wurden Kandidatengenstudien durchgeführt. Dabei untersuchte man auf Grundlage unterschiedlicher, v. a. aber pathophysiologisch plausibler Überlegungen Gene mit hoher Relevanz für die untersuchten Phänotypen. Dieser Ansatz war für Essstörungen nicht sehr erfolgreich, für die Gewichtsregulation konnte eine Handvoll Gene identifiziert werden. Verbunden mit großen methodischen Fortschritten in der genetischen Forschung und v. a. der Etablierung sogenannter genomweiter Assoziationsstudien (GWAS) Anfang der 2000er-Jahre konnten bislang über 1000 Varianten/Genorte detektiert werden, die das Körpergewicht beeinflussen. Für die Essstörung Anorexia nervosa (AN) sind aktuell acht solcher Genorte beschrieben. Diese Ergebnisse, aber auch aktuelle Ansätze zu phänotypübergreifenden Analysen lassen Einblicke in die komplexe Regulation des Körpergewichtes zu und haben zudem unerwartete Pathomechanismen für AN aufgezeigt. ' author: - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Yiran full_name: Zheng, Yiran last_name: Zheng - first_name: Luisa S. full_name: Rajcsanyi, Luisa S. last_name: Rajcsanyi - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Anke full_name: Hinney, Anke last_name: Hinney citation: ama: Hirtz R, Zheng Y, Rajcsanyi LS, et al. Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. 2021;50(3):175-185. doi:10.1024/1422-4917/a000829 apa: Hirtz, R., Zheng, Y., Rajcsanyi, L. S., Libuda, L., Antel, J., Peters, T., Hebebrand, J., & Hinney, A. (2021). Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 50(3), 175–185. https://doi.org/10.1024/1422-4917/a000829 bibtex: '@article{Hirtz_Zheng_Rajcsanyi_Libuda_Antel_Peters_Hebebrand_Hinney_2021, title={Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts}, volume={50}, DOI={10.1024/1422-4917/a000829}, number={3}, journal={Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie}, publisher={Hogrefe Publishing Group}, author={Hirtz, Raphael and Zheng, Yiran and Rajcsanyi, Luisa S. and Libuda, Lars and Antel, Jochen and Peters, Triinu and Hebebrand, Johannes and Hinney, Anke}, year={2021}, pages={175–185} }' chicago: 'Hirtz, Raphael, Yiran Zheng, Luisa S. Rajcsanyi, Lars Libuda, Jochen Antel, Triinu Peters, Johannes Hebebrand, and Anke Hinney. “Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts.” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 50, no. 3 (2021): 175–85. https://doi.org/10.1024/1422-4917/a000829.' ieee: 'R. Hirtz et al., “Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts,” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, vol. 50, no. 3, pp. 175–185, 2021, doi: 10.1024/1422-4917/a000829.' mla: Hirtz, Raphael, et al. “Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel                    der Anorexia nervosa und der Varianz des Körpergewichts.” Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, vol. 50, no. 3, Hogrefe Publishing Group, 2021, pp. 175–85, doi:10.1024/1422-4917/a000829. short: R. Hirtz, Y. Zheng, L.S. Rajcsanyi, L. Libuda, J. Antel, T. Peters, J. Hebebrand, A. Hinney, Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 50 (2021) 175–185. date_created: 2022-11-03T11:31:50Z date_updated: 2023-01-11T16:58:49Z department: - _id: '35' doi: 10.1024/1422-4917/a000829 intvolume: ' 50' issue: '3' keyword: - Psychiatry and Mental health - Clinical Psychology - General Medicine - Pediatrics - Perinatology and Child Health language: - iso: ger page: 175-185 publication: Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie publication_identifier: issn: - 1422-4917 - 1664-2880 publication_status: published publisher: Hogrefe Publishing Group status: public title: Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel der Anorexia nervosa und der Varianz des Körpergewichts type: journal_article user_id: '88682' volume: 50 year: '2021' ... --- _id: '46078' abstract: - lang: eng text: "Abstract\r\n Aim\r\n \ To identify and summarize the evidence for the effect of health-oriented leadership interventions on health and well-being outcomes at the employee level following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (Moher et al. 2009).\r\n \r\n \ Subject and Methods\r\n A systematic search of relevant studies was conducted in multiple databases. Randomized controlled trials (RCTs), cluster-randomized controlled trials (cRCTs) and controlled before–after studies (CBAs) were included based on the following criteria: interventions that addressed supervisors, to raise awareness for the importance of health issues, teach mindfulness practices for conscious awareness, reduce stress and promote resources at the level of individual behavior, and evaluated the effect on at least one outcome of psychomental stress, absenteeism and well-being on the employee level.\r\n \r\n Results\r\n \ Of 6126 publications retrieved, ten studies were identified for analysis. Significant effects of leadership training were reported on exhaustion tendency, self-reported sickness absence, work-related sickness absence and job satisfaction in studies comparing health-oriented training programs to no intervention. Studies comparing health-oriented leadership training to other training did not report significant effects. Risk of bias was judged to be high in seven studies and unclear in three studies.\r\n \r\n \ Conclusion\r\n Evidence for the effectiveness of health-oriented leadership interventions on employees’ stress, absenteeism or well-being is judged to be low, clearly indicating the need for more and higher-quality research.\r\n " author: - first_name: Indra full_name: Dannheim, Indra last_name: Dannheim - first_name: Helena full_name: Ludwig-Walz, Helena last_name: Ludwig-Walz - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Valerie full_name: Grimm, Valerie last_name: Grimm - first_name: Anja full_name: Kroke, Anja last_name: Kroke citation: ama: 'Dannheim I, Ludwig-Walz H, Buyken A, Grimm V, Kroke A. Effectiveness of health-oriented leadership interventions for improving health and wellbeing of employees: a systematic review. Journal of Public Health. 2021;30(12):2777-2789. doi:10.1007/s10389-021-01664-1' apa: 'Dannheim, I., Ludwig-Walz, H., Buyken, A., Grimm, V., & Kroke, A. (2021). Effectiveness of health-oriented leadership interventions for improving health and wellbeing of employees: a systematic review. Journal of Public Health, 30(12), 2777–2789. https://doi.org/10.1007/s10389-021-01664-1' bibtex: '@article{Dannheim_Ludwig-Walz_Buyken_Grimm_Kroke_2021, title={Effectiveness of health-oriented leadership interventions for improving health and wellbeing of employees: a systematic review}, volume={30}, DOI={10.1007/s10389-021-01664-1}, number={12}, journal={Journal of Public Health}, publisher={Springer Science and Business Media LLC}, author={Dannheim, Indra and Ludwig-Walz, Helena and Buyken, Anette and Grimm, Valerie and Kroke, Anja}, year={2021}, pages={2777–2789} }' chicago: 'Dannheim, Indra, Helena Ludwig-Walz, Anette Buyken, Valerie Grimm, and Anja Kroke. “Effectiveness of Health-Oriented Leadership Interventions for Improving Health and Wellbeing of Employees: A Systematic Review.” Journal of Public Health 30, no. 12 (2021): 2777–89. https://doi.org/10.1007/s10389-021-01664-1.' ieee: 'I. Dannheim, H. Ludwig-Walz, A. Buyken, V. Grimm, and A. Kroke, “Effectiveness of health-oriented leadership interventions for improving health and wellbeing of employees: a systematic review,” Journal of Public Health, vol. 30, no. 12, pp. 2777–2789, 2021, doi: 10.1007/s10389-021-01664-1.' mla: 'Dannheim, Indra, et al. “Effectiveness of Health-Oriented Leadership Interventions for Improving Health and Wellbeing of Employees: A Systematic Review.” Journal of Public Health, vol. 30, no. 12, Springer Science and Business Media LLC, 2021, pp. 2777–89, doi:10.1007/s10389-021-01664-1.' short: I. Dannheim, H. Ludwig-Walz, A. Buyken, V. Grimm, A. Kroke, Journal of Public Health 30 (2021) 2777–2789. date_created: 2023-07-18T09:34:03Z date_updated: 2023-07-18T09:35:41Z department: - _id: '22' doi: 10.1007/s10389-021-01664-1 intvolume: ' 30' issue: '12' keyword: - Public Health - Environmental and Occupational Health language: - iso: eng page: 2777-2789 publication: Journal of Public Health publication_identifier: issn: - 2198-1833 - 1613-2238 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Effectiveness of health-oriented leadership interventions for improving health and wellbeing of employees: a systematic review' type: journal_article user_id: '92491' volume: 30 year: '2021' ... --- _id: '28011' author: - first_name: Jennie full_name: Brand-Miller, Jennie last_name: Brand-Miller - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken citation: ama: Brand-Miller J, Buyken A. Mapping postprandial responses sets the scene for targeted dietary advice. Nature Medicine. Published online 2020:828-830. doi:10.1038/s41591-020-0909-1 apa: Brand-Miller, J., & Buyken, A. (2020). Mapping postprandial responses sets the scene for targeted dietary advice. Nature Medicine, 828–830. https://doi.org/10.1038/s41591-020-0909-1 bibtex: '@article{Brand-Miller_Buyken_2020, title={Mapping postprandial responses sets the scene for targeted dietary advice}, DOI={10.1038/s41591-020-0909-1}, journal={Nature Medicine}, author={Brand-Miller, Jennie and Buyken, Anette}, year={2020}, pages={828–830} }' chicago: Brand-Miller, Jennie, and Anette Buyken. “Mapping Postprandial Responses Sets the Scene for Targeted Dietary Advice.” Nature Medicine, 2020, 828–30. https://doi.org/10.1038/s41591-020-0909-1. ieee: 'J. Brand-Miller and A. Buyken, “Mapping postprandial responses sets the scene for targeted dietary advice,” Nature Medicine, pp. 828–830, 2020, doi: 10.1038/s41591-020-0909-1.' mla: Brand-Miller, Jennie, and Anette Buyken. “Mapping Postprandial Responses Sets the Scene for Targeted Dietary Advice.” Nature Medicine, 2020, pp. 828–30, doi:10.1038/s41591-020-0909-1. short: J. Brand-Miller, A. Buyken, Nature Medicine (2020) 828–830. date_created: 2021-11-27T13:12:10Z date_updated: 2022-01-06T06:57:50Z department: - _id: '35' - _id: '22' - _id: '571' doi: 10.1038/s41591-020-0909-1 language: - iso: eng page: 828-830 publication: Nature Medicine publication_identifier: issn: - 1078-8956 - 1546-170X publication_status: published status: public title: Mapping postprandial responses sets the scene for targeted dietary advice type: journal_article user_id: '49428' year: '2020' ... --- _id: '26526' author: - first_name: Monika full_name: Gappa, Monika last_name: Gappa - first_name: Birgit full_name: Filipiak‐Pittroff, Birgit last_name: Filipiak‐Pittroff - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Andrea full_name: Berg, Andrea last_name: Berg - first_name: Sibylle full_name: Koletzko, Sibylle last_name: Koletzko - first_name: Carl‐Peter full_name: Bauer, Carl‐Peter last_name: Bauer - first_name: Joachim full_name: Heinrich, Joachim last_name: Heinrich - first_name: Tamara full_name: Schikowski, Tamara last_name: Schikowski - first_name: Dietrich full_name: Berdel, Dietrich last_name: Berdel - first_name: Marie full_name: Standl, Marie last_name: Standl citation: ama: Gappa M, Filipiak‐Pittroff B, Libuda L, et al. Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study. Allergy. Published online 2020:1903-1907. doi:10.1111/all.14709 apa: Gappa, M., Filipiak‐Pittroff, B., Libuda, L., Berg, A., Koletzko, S., Bauer, C., Heinrich, J., Schikowski, T., Berdel, D., & Standl, M. (2020). Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study. Allergy, 1903–1907. https://doi.org/10.1111/all.14709 bibtex: '@article{Gappa_Filipiak‐Pittroff_Libuda_Berg_Koletzko_Bauer_Heinrich_Schikowski_Berdel_Standl_2020, title={Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study}, DOI={10.1111/all.14709}, journal={Allergy}, author={Gappa, Monika and Filipiak‐Pittroff, Birgit and Libuda, Lars and Berg, Andrea and Koletzko, Sibylle and Bauer, Carl‐Peter and Heinrich, Joachim and Schikowski, Tamara and Berdel, Dietrich and Standl, Marie}, year={2020}, pages={1903–1907} }' chicago: Gappa, Monika, Birgit Filipiak‐Pittroff, Lars Libuda, Andrea Berg, Sibylle Koletzko, Carl‐Peter Bauer, Joachim Heinrich, Tamara Schikowski, Dietrich Berdel, and Marie Standl. “Long‐term Effects of Hydrolyzed Formulae on Atopic Diseases in the GINI Study.” Allergy, 2020, 1903–7. https://doi.org/10.1111/all.14709. ieee: 'M. Gappa et al., “Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study,” Allergy, pp. 1903–1907, 2020, doi: 10.1111/all.14709.' mla: Gappa, Monika, et al. “Long‐term Effects of Hydrolyzed Formulae on Atopic Diseases in the GINI Study.” Allergy, 2020, pp. 1903–07, doi:10.1111/all.14709. short: M. Gappa, B. Filipiak‐Pittroff, L. Libuda, A. Berg, S. Koletzko, C. Bauer, J. Heinrich, T. Schikowski, D. Berdel, M. Standl, Allergy (2020) 1903–1907. date_created: 2021-10-19T09:56:15Z date_updated: 2022-01-06T06:57:21Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.1111/all.14709 language: - iso: eng page: 1903-1907 publication: Allergy publication_identifier: issn: - 0105-4538 - 1398-9995 publication_status: published status: public title: Long‐term effects of hydrolyzed formulae on atopic diseases in the GINI study type: journal_article user_id: '49428' year: '2020' ... --- _id: '26527' abstract: - lang: eng text: "Abstract\r\n Background\r\n \ While observational studies revealed an inverse association between serum 25(OH)vitamin D (25(OH)D) and the risk of attention deficit/hyperactivity disorder (ADHD), the causality of this relationship remains unclear.\r\n \ \r\n Methods\r\n \ We conducted a bidirectional two-sample Mendelian Randomization (MR) study to examine whether 25(OH)D has an effect on the risk to develop ADHD or vice versa. Information on single nucleotide polymorphisms (SNP) associated with serum 25(OH)D was obtained from a genome-wide association study (GWAS) considering phenotype data from 79,366 individuals of European ancestry. Data on risk for ADHD were derived from a GWAS analysis with 20,183 individuals diagnosed with ADHD and 35,191 controls. For our analysis, we considered effect sizes based on the European participants (19,099 cases and 34,194 controls).\r\n \r\n \ Results\r\n Single SNP analyses showed a causal effect of vitamin D on ADHD risk for only one SNP (rs12785878, p = 0.024). The overall MR estimates did not reveal a causal effect of 25(OH)D on risk for ADHD. In the reverse analysis, neither any single nor the multi-SNP MR analyses showed a causal effect of ADHD on 25(OH)D.\r\n \r\n Conclusion\r\n \ Results from this two-sample MR study did not confirm a causal effect of 25(OH)D on ADHD or vice versa. Accordingly, our study does not provide evidence that improving 25(OH)D via supplementation could reduce the risk of developing ADHD.\r\n " author: - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Roaa full_name: Naaresh, Roaa last_name: Naaresh - first_name: Christine full_name: Ludwig, Christine last_name: Ludwig - first_name: Björn-Hergen full_name: Laabs, Björn-Hergen last_name: Laabs - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Triinu full_name: Peters, Triinu last_name: Peters citation: ama: Libuda L, Naaresh R, Ludwig C, et al. A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder. European Journal of Nutrition. Published online 2020:2581-2591. doi:10.1007/s00394-020-02439-2 apa: Libuda, L., Naaresh, R., Ludwig, C., Laabs, B.-H., Antel, J., Föcker, M., Hebebrand, J., Hinney, A., & Peters, T. (2020). A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder. European Journal of Nutrition, 2581–2591. https://doi.org/10.1007/s00394-020-02439-2 bibtex: '@article{Libuda_Naaresh_Ludwig_Laabs_Antel_Föcker_Hebebrand_Hinney_Peters_2020, title={A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder}, DOI={10.1007/s00394-020-02439-2}, journal={European Journal of Nutrition}, author={Libuda, Lars and Naaresh, Roaa and Ludwig, Christine and Laabs, Björn-Hergen and Antel, Jochen and Föcker, Manuel and Hebebrand, Johannes and Hinney, Anke and Peters, Triinu}, year={2020}, pages={2581–2591} }' chicago: Libuda, Lars, Roaa Naaresh, Christine Ludwig, Björn-Hergen Laabs, Jochen Antel, Manuel Föcker, Johannes Hebebrand, Anke Hinney, and Triinu Peters. “A Mendelian Randomization Study on Causal Effects of 25(OH)Vitamin D Levels on Attention Deficit/Hyperactivity Disorder.” European Journal of Nutrition, 2020, 2581–91. https://doi.org/10.1007/s00394-020-02439-2. ieee: 'L. Libuda et al., “A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder,” European Journal of Nutrition, pp. 2581–2591, 2020, doi: 10.1007/s00394-020-02439-2.' mla: Libuda, Lars, et al. “A Mendelian Randomization Study on Causal Effects of 25(OH)Vitamin D Levels on Attention Deficit/Hyperactivity Disorder.” European Journal of Nutrition, 2020, pp. 2581–91, doi:10.1007/s00394-020-02439-2. short: L. Libuda, R. Naaresh, C. Ludwig, B.-H. Laabs, J. Antel, M. Föcker, J. Hebebrand, A. Hinney, T. Peters, European Journal of Nutrition (2020) 2581–2591. date_created: 2021-10-19T09:57:27Z date_updated: 2022-01-06T06:57:21Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.1007/s00394-020-02439-2 language: - iso: eng page: 2581-2591 publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published status: public title: A mendelian randomization study on causal effects of 25(OH)vitamin D levels on attention deficit/hyperactivity disorder type: journal_article user_id: '49428' year: '2020' ... --- _id: '26529' abstract: - lang: eng text: "Abstract\r\n Purpose\r\n \ The influences of nutrition in childhood on puberty onset could have sustained consequences for health and wellbeing later in life. The aim of this study was to investigate the prospective association of diet quality prior to puberty with the timing of puberty onset.\r\n \r\n \ Methods\r\n We considered data from 3983 SCCNG (Southwest China Childhood Nutrition and Growth) study participants with dietary data, anthropometric measurement, and information on potential confounders at their baseline assessment (mean age: 7.1 years for girls and 7.3 years for boys; mean length of follow-up was 4.2 years). Cox proportional hazard regression estimating hazard ratios (HRs) and 95% confidence intervals (CIs) were used to examine the relationship between diet quality and puberty onset. Dietary intake at baseline was assessed using a validated food frequency questionnaire. Diet quality was determined using the Chinese Children Dietary Index (CCDI) which measures adherence to current dietary recommendations (theoretical range: 0–160 points). Age at Tanner stage 2 for breast/genital development (B2/G2), menarche or voice break (M/VB) were used as pubertal markers.\r\n\r\n \r\n \ Results\r\n The CCDI score ranged from 56.2 to 136.3 for girls and 46.1–131.5 for boys. Pubertal markers consistently indicate that girls and boys with higher diet quality were more likely to enter their puberty later than their counterparts with lower CCDI scores (higher vs. lower CCDI tertiles: adjusted HR for age at B2: 0.85 (95% CI, 0.81–0.94), p for trend = 0.02; G2: 0.86 (95% CI,0.80–0.96), p for trend = 0.02; M: 0.86 (95% CI,0.80–0.95), p for trend = 0.02; VB: 0.86 (95% CI,0.79–0.98), p for trend = 0.03), after adjustment for paternal education level, baseline energy intake, and pre-pubertal body fat.\r\n \r\n \ Conclusions\r\n Our data suggested a later puberty onset and later timing of progressed puberty stages in children with a high diet quality, which were independent of pre-pubertal body fat.\r\n " author: - first_name: Ruonan full_name: Duan, Ruonan last_name: Duan - first_name: Tian full_name: Qiao, Tian last_name: Qiao - first_name: Yue full_name: Chen, Yue last_name: Chen - first_name: Mengxue full_name: Chen, Mengxue last_name: Chen - first_name: Hongmei full_name: Xue, Hongmei last_name: Xue - first_name: Xue full_name: Zhou, Xue last_name: Zhou - first_name: Mingzhe full_name: Yang, Mingzhe last_name: Yang - first_name: Yan full_name: Liu, Yan last_name: Liu - first_name: Li full_name: Zhao, Li last_name: Zhao - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Guo full_name: Cheng, Guo last_name: Cheng citation: ama: Duan R, Qiao T, Chen Y, et al. The overall diet quality in childhood is prospectively associated with the timing of puberty. European Journal of Nutrition. Published online 2020:2423-2434. doi:10.1007/s00394-020-02425-8 apa: Duan, R., Qiao, T., Chen, Y., Chen, M., Xue, H., Zhou, X., Yang, M., Liu, Y., Zhao, L., Libuda, L., & Cheng, G. (2020). The overall diet quality in childhood is prospectively associated with the timing of puberty. European Journal of Nutrition, 2423–2434. https://doi.org/10.1007/s00394-020-02425-8 bibtex: '@article{Duan_Qiao_Chen_Chen_Xue_Zhou_Yang_Liu_Zhao_Libuda_et al._2020, title={The overall diet quality in childhood is prospectively associated with the timing of puberty}, DOI={10.1007/s00394-020-02425-8}, journal={European Journal of Nutrition}, author={Duan, Ruonan and Qiao, Tian and Chen, Yue and Chen, Mengxue and Xue, Hongmei and Zhou, Xue and Yang, Mingzhe and Liu, Yan and Zhao, Li and Libuda, Lars and et al.}, year={2020}, pages={2423–2434} }' chicago: Duan, Ruonan, Tian Qiao, Yue Chen, Mengxue Chen, Hongmei Xue, Xue Zhou, Mingzhe Yang, et al. “The Overall Diet Quality in Childhood Is Prospectively Associated with the Timing of Puberty.” European Journal of Nutrition, 2020, 2423–34. https://doi.org/10.1007/s00394-020-02425-8. ieee: 'R. Duan et al., “The overall diet quality in childhood is prospectively associated with the timing of puberty,” European Journal of Nutrition, pp. 2423–2434, 2020, doi: 10.1007/s00394-020-02425-8.' mla: Duan, Ruonan, et al. “The Overall Diet Quality in Childhood Is Prospectively Associated with the Timing of Puberty.” European Journal of Nutrition, 2020, pp. 2423–34, doi:10.1007/s00394-020-02425-8. short: R. Duan, T. Qiao, Y. Chen, M. Chen, H. Xue, X. Zhou, M. Yang, Y. Liu, L. Zhao, L. Libuda, G. Cheng, European Journal of Nutrition (2020) 2423–2434. date_created: 2021-10-19T09:58:18Z date_updated: 2022-01-06T06:57:21Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.1007/s00394-020-02425-8 language: - iso: eng page: 2423-2434 publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published status: public title: The overall diet quality in childhood is prospectively associated with the timing of puberty type: journal_article user_id: '49428' year: '2020' ... --- _id: '26872' author: - first_name: Nina full_name: Klünder, Nina id: '91015' last_name: Klünder citation: ama: Klünder N. Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung. Beltz Juventa; 2020. apa: Klünder, N. (2020). Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung. Beltz Juventa. bibtex: '@book{Klünder_2020, place={Weinheim}, title={Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung}, publisher={Beltz Juventa}, author={Klünder, Nina}, year={2020} }' chicago: 'Klünder, Nina. Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung. Weinheim: Beltz Juventa, 2020.' ieee: 'N. Klünder, Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung. Weinheim: Beltz Juventa, 2020.' mla: Klünder, Nina. Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung. Beltz Juventa, 2020. short: N. Klünder, Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung, Beltz Juventa, Weinheim, 2020. date_created: 2021-10-26T07:50:05Z date_updated: 2022-01-06T06:57:30Z department: - _id: '17' - _id: '22' - _id: '394' language: - iso: ger page: '135' place: Weinheim publication_identifier: unknown: - 978-3-7799-5550-4 publication_status: published publisher: Beltz Juventa status: public title: Die Ernährungsversorgung in Familien zwischen Zeit, Alltag und Haushaltsführung. Eine Mixed-Methods-Untersuchung type: book user_id: '61597' year: '2020' ... --- _id: '26886' author: - first_name: Heinz full_name: Müller, Heinz last_name: Müller - first_name: Nina full_name: Klünder, Nina id: '91015' last_name: Klünder citation: ama: Müller H, Klünder N. Der Jugendamts-Monitor. Aufgaben – Trends – Daten.; 2020. apa: Müller, H., & Klünder, N. (2020). Der Jugendamts-Monitor. Aufgaben – Trends – Daten. bibtex: '@book{Müller_Klünder_2020, place={Köln}, title={Der Jugendamts-Monitor. Aufgaben – Trends – Daten}, author={Müller, Heinz and Klünder, Nina}, year={2020} }' chicago: Müller, Heinz, and Nina Klünder. Der Jugendamts-Monitor. Aufgaben – Trends – Daten. Köln, 2020. ieee: H. Müller and N. Klünder, Der Jugendamts-Monitor. Aufgaben – Trends – Daten. Köln, 2020. mla: Müller, Heinz, and Nina Klünder. Der Jugendamts-Monitor. Aufgaben – Trends – Daten. 2020. short: H. Müller, N. Klünder, Der Jugendamts-Monitor. Aufgaben – Trends – Daten, Köln, 2020. date_created: 2021-10-26T10:00:40Z date_updated: 2022-01-06T06:57:30Z department: - _id: '17' - _id: '22' - _id: '394' language: - iso: ger page: '74' place: Köln publication_status: published related_material: link: - relation: confirmation url: 'https://www.unterstuetzung-die-ankommt.de/media/filer_public/fa/4b/fa4b2dff-7a2c-4257-87fe-f01f18503c9b/jugendamtsmonitor-bag-landesjugendaemter-web.pdf ' status: public title: Der Jugendamts-Monitor. Aufgaben – Trends – Daten type: report user_id: '61597' year: '2020' ... --- _id: '27013' abstract: - lang: eng text: AbstractFlavonoids are suggested to reduce disease risk. Since dietary habits are acquired during early life, describing age and time trends of flavonoid intake and major food sources are important for monitoring and disease prevention in later life. We aimed to describe total flavonoid intake and food sources and to investigate age and time trends of flavonoid intake in 3–18-year-olds, from the Dortmund Nutritional and Anthropometric Longitudinally Designed study from 1985 to 2016. Intake was assessed annually using 3-d weighed food records (WFR). Flavonoid values were assigned using the United States Department of Agriculture database. Foods contributing to intake were determined. Age and time trends in total flavonoid and isoflavone density were analysed by sex with PROC MIXED. In total, 1312 children completed 10 758 WFR. Across all ages, daily mean total flavonoid density was lower in boys compared with girls (134 v. 146 mg/4184 kJ) and no difference in median isoflavone density (0·04 mg/4184 kJ per d) was found. The top five foods contributing to total flavonoid intake were apple with peel (15·0/17·1 %), strawberries (5·9/6·1 %), chocolate spread (3·9/3·5 %), orange juice (3·5/3·4 %) and pasta (3·5/3·4 %) for boys and girls, respectively. Overall, in boys, total flavonoid density decreased over the course of age and time. In girls, there was no association with age or time. In both sexes, isoflavone density followed a U-shaped age trend with no change over time. From a public health perspective, the overall observed downwards trend of flavonoid intake in boys deserves attention. Future initiatives should be tailored at maintaining a high flavonoid density as children age, specifically among boys. author: - first_name: Johanna full_name: Rienks, Johanna last_name: Rienks - first_name: Katharina J. full_name: Penczynski, Katharina J. last_name: Penczynski - first_name: Sarah full_name: Schmitting, Sarah last_name: Schmitting - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Ute full_name: Nöthlings, Ute last_name: Nöthlings citation: ama: 'Rienks J, Penczynski KJ, Schmitting S, Buyken A, Nöthlings U. Dietary flavonoids among children and adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study: intake, food sources and trends from 1985 until 2016. British Journal of Nutrition. Published online 2020:1198-1206. doi:10.1017/s000711452000183x' apa: 'Rienks, J., Penczynski, K. J., Schmitting, S., Buyken, A., & Nöthlings, U. (2020). Dietary flavonoids among children and adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study: intake, food sources and trends from 1985 until 2016. British Journal of Nutrition, 1198–1206. https://doi.org/10.1017/s000711452000183x' bibtex: '@article{Rienks_Penczynski_Schmitting_Buyken_Nöthlings_2020, title={Dietary flavonoids among children and adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study: intake, food sources and trends from 1985 until 2016}, DOI={10.1017/s000711452000183x}, journal={British Journal of Nutrition}, author={Rienks, Johanna and Penczynski, Katharina J. and Schmitting, Sarah and Buyken, Anette and Nöthlings, Ute}, year={2020}, pages={1198–1206} }' chicago: 'Rienks, Johanna, Katharina J. Penczynski, Sarah Schmitting, Anette Buyken, and Ute Nöthlings. “Dietary Flavonoids among Children and Adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study: Intake, Food Sources and Trends from 1985 until 2016.” British Journal of Nutrition, 2020, 1198–1206. https://doi.org/10.1017/s000711452000183x.' ieee: 'J. Rienks, K. J. Penczynski, S. Schmitting, A. Buyken, and U. Nöthlings, “Dietary flavonoids among children and adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study: intake, food sources and trends from 1985 until 2016,” British Journal of Nutrition, pp. 1198–1206, 2020, doi: 10.1017/s000711452000183x.' mla: 'Rienks, Johanna, et al. “Dietary Flavonoids among Children and Adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study: Intake, Food Sources and Trends from 1985 until 2016.” British Journal of Nutrition, 2020, pp. 1198–206, doi:10.1017/s000711452000183x.' short: J. Rienks, K.J. Penczynski, S. Schmitting, A. Buyken, U. Nöthlings, British Journal of Nutrition (2020) 1198–1206. date_created: 2021-10-29T13:58:15Z date_updated: 2022-01-06T06:57:32Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.1017/s000711452000183x language: - iso: eng page: 1198-1206 publication: British Journal of Nutrition publication_identifier: issn: - 0007-1145 - 1475-2662 publication_status: published status: public title: 'Dietary flavonoids among children and adolescents in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study: intake, food sources and trends from 1985 until 2016' type: journal_article user_id: '61597' year: '2020' ... --- _id: '27019' abstract: - lang: eng text: AbstractTo examine the hypothesis that normalization of low circulating leptin levels in patients with anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity were treated off-label with metreleptin (recombinant human leptin) for up to 14 days. Drive for activity, repetitive thoughts of food, inner restlessness, and weight phobia decreased in two patients. Surprisingly, depression improved rapidly in all patients. No serious adverse events occurred. Due to obvious limitations of uncontrolled case series, placebo-controlled clinical trials are mandatory to confirm the observed rapid onset of beneficial effects. Our findings suggest an important role of hypoleptinemia in the mental and behavioral phenotype of anorexia nervosa. author: - first_name: Gabriella full_name: Milos, Gabriella last_name: Milos - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Lisa-Katrin full_name: Kaufmann, Lisa-Katrin last_name: Kaufmann - first_name: Nikolaus full_name: Barth, Nikolaus last_name: Barth - first_name: Antonia full_name: Koller, Antonia last_name: Koller - first_name: Susanne full_name: Tan, Susanne last_name: Tan - first_name: Urban full_name: Wiesing, Urban last_name: Wiesing - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Martin full_name: Wabitsch, Martin last_name: Wabitsch - first_name: Roland full_name: von Känel, Roland last_name: von Känel - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand citation: ama: 'Milos G, Antel J, Kaufmann L-K, et al. Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects. Translational Psychiatry. Published online 2020. doi:10.1038/s41398-020-00977-1' apa: 'Milos, G., Antel, J., Kaufmann, L.-K., Barth, N., Koller, A., Tan, S., Wiesing, U., Hinney, A., Libuda, L., Wabitsch, M., von Känel, R., & Hebebrand, J. (2020). Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects. Translational Psychiatry. https://doi.org/10.1038/s41398-020-00977-1' bibtex: '@article{Milos_Antel_Kaufmann_Barth_Koller_Tan_Wiesing_Hinney_Libuda_Wabitsch_et al._2020, title={Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects}, DOI={10.1038/s41398-020-00977-1}, journal={Translational Psychiatry}, author={Milos, Gabriella and Antel, Jochen and Kaufmann, Lisa-Katrin and Barth, Nikolaus and Koller, Antonia and Tan, Susanne and Wiesing, Urban and Hinney, Anke and Libuda, Lars and Wabitsch, Martin and et al.}, year={2020} }' chicago: 'Milos, Gabriella, Jochen Antel, Lisa-Katrin Kaufmann, Nikolaus Barth, Antonia Koller, Susanne Tan, Urban Wiesing, et al. “Short-Term Metreleptin Treatment of Patients with Anorexia Nervosa: Rapid on-Set of Beneficial Cognitive, Emotional, and Behavioral Effects.” Translational Psychiatry, 2020. https://doi.org/10.1038/s41398-020-00977-1.' ieee: 'G. Milos et al., “Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects,” Translational Psychiatry, 2020, doi: 10.1038/s41398-020-00977-1.' mla: 'Milos, Gabriella, et al. “Short-Term Metreleptin Treatment of Patients with Anorexia Nervosa: Rapid on-Set of Beneficial Cognitive, Emotional, and Behavioral Effects.” Translational Psychiatry, 2020, doi:10.1038/s41398-020-00977-1.' short: G. Milos, J. Antel, L.-K. Kaufmann, N. Barth, A. Koller, S. Tan, U. Wiesing, A. Hinney, L. Libuda, M. Wabitsch, R. von Känel, J. Hebebrand, Translational Psychiatry (2020). date_created: 2021-11-01T18:58:28Z date_updated: 2022-01-06T06:57:32Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.1038/s41398-020-00977-1 language: - iso: eng publication: Translational Psychiatry publication_identifier: issn: - 2158-3188 publication_status: published status: public title: 'Short-term metreleptin treatment of patients with anorexia nervosa: rapid on-set of beneficial cognitive, emotional, and behavioral effects' type: journal_article user_id: '49428' year: '2020' ... --- _id: '27020' author: - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Lena full_name: Nüllig, Lena last_name: Nüllig - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Roaa full_name: Naaresh, Roaa last_name: Naaresh - first_name: Björn-Hergen full_name: Laabs, Björn-Hergen last_name: Laabs - first_name: Lisa full_name: Tegeler, Lisa last_name: Tegeler - first_name: Chaima full_name: Amhaouach, Chaima last_name: Amhaouach - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand citation: ama: 'Peters T, Nüllig L, Antel J, et al. The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study. Frontiers in Genetics. Published online 2020. doi:10.3389/fgene.2020.00373' apa: 'Peters, T., Nüllig, L., Antel, J., Naaresh, R., Laabs, B.-H., Tegeler, L., Amhaouach, C., Libuda, L., Hinney, A., & Hebebrand, J. (2020). The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study. Frontiers in Genetics. https://doi.org/10.3389/fgene.2020.00373' bibtex: '@article{Peters_Nüllig_Antel_Naaresh_Laabs_Tegeler_Amhaouach_Libuda_Hinney_Hebebrand_2020, title={The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study}, DOI={10.3389/fgene.2020.00373}, journal={Frontiers in Genetics}, author={Peters, Triinu and Nüllig, Lena and Antel, Jochen and Naaresh, Roaa and Laabs, Björn-Hergen and Tegeler, Lisa and Amhaouach, Chaima and Libuda, Lars and Hinney, Anke and Hebebrand, Johannes}, year={2020} }' chicago: 'Peters, Triinu, Lena Nüllig, Jochen Antel, Roaa Naaresh, Björn-Hergen Laabs, Lisa Tegeler, Chaima Amhaouach, Lars Libuda, Anke Hinney, and Johannes Hebebrand. “The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study.” Frontiers in Genetics, 2020. https://doi.org/10.3389/fgene.2020.00373.' ieee: 'T. Peters et al., “The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study,” Frontiers in Genetics, 2020, doi: 10.3389/fgene.2020.00373.' mla: 'Peters, Triinu, et al. “The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study.” Frontiers in Genetics, 2020, doi:10.3389/fgene.2020.00373.' short: T. Peters, L. Nüllig, J. Antel, R. Naaresh, B.-H. Laabs, L. Tegeler, C. Amhaouach, L. Libuda, A. Hinney, J. Hebebrand, Frontiers in Genetics (2020). date_created: 2021-11-01T19:00:58Z date_updated: 2022-01-06T06:57:32Z department: - _id: '35' - _id: '22' - _id: '395' doi: 10.3389/fgene.2020.00373 language: - iso: eng publication: Frontiers in Genetics publication_identifier: issn: - 1664-8021 publication_status: published status: public title: 'The Role of Genetic Variation of BMI, Body Composition, and Fat Distribution for Mental Traits and Disorders: A Look-Up and Mendelian Randomization Study' type: journal_article user_id: '49428' year: '2020' ... --- _id: '27795' author: - first_name: Yuliya full_name: Kupriyanova, Yuliya last_name: Kupriyanova - first_name: Oana Patricia full_name: Zaharia, Oana Patricia last_name: Zaharia - first_name: Pavel full_name: Bobrov, Pavel last_name: Bobrov - first_name: Yanislava full_name: Karusheva, Yanislava last_name: Karusheva - first_name: Volker full_name: Burkart, Volker last_name: Burkart - first_name: Julia full_name: Szendroedi, Julia last_name: Szendroedi - first_name: Jong-Hee full_name: Hwang, Jong-Hee last_name: Hwang - first_name: Michael full_name: Roden, Michael last_name: Roden - first_name: M. full_name: Roden, M. last_name: Roden - first_name: H. full_name: Al-Hasani, H. last_name: Al-Hasani - first_name: V. full_name: Burkart, V. last_name: Burkart - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: G. full_name: Geerling, G. last_name: Geerling - first_name: J.H. full_name: Hwang, J.H. last_name: Hwang - first_name: C. full_name: Herder, C. last_name: Herder - first_name: A. full_name: Icks, A. last_name: Icks - first_name: K. full_name: Jandeleit-Dahm, K. last_name: Jandeleit-Dahm - first_name: S. full_name: Kahl, S. last_name: Kahl - first_name: J. full_name: Kotzka, J. last_name: Kotzka - first_name: O. full_name: Kuss, O. last_name: Kuss - first_name: E. full_name: Lammert, E. last_name: Lammert - first_name: S. full_name: Trenkamp, S. last_name: Trenkamp - first_name: W. full_name: Rathmann, W. last_name: Rathmann - first_name: J. full_name: Szendroedi, J. last_name: Szendroedi - first_name: D. full_name: Ziegler, D. last_name: Ziegler citation: ama: Kupriyanova Y, Zaharia OP, Bobrov P, et al. Early changes in hepatic energy metabolism and lipid content in recent-onset type 1 and 2 diabetes mellitus. Journal of Hepatology. Published online 2020:1028-1037. doi:10.1016/j.jhep.2020.11.030 apa: Kupriyanova, Y., Zaharia, O. P., Bobrov, P., Karusheva, Y., Burkart, V., Szendroedi, J., Hwang, J.-H., Roden, M., Roden, M., Al-Hasani, H., Burkart, V., Buyken, A., Geerling, G., Hwang, J. H., Herder, C., Icks, A., Jandeleit-Dahm, K., Kahl, S., Kotzka, J., … Ziegler, D. (2020). Early changes in hepatic energy metabolism and lipid content in recent-onset type 1 and 2 diabetes mellitus. Journal of Hepatology, 1028–1037. https://doi.org/10.1016/j.jhep.2020.11.030 bibtex: '@article{Kupriyanova_Zaharia_Bobrov_Karusheva_Burkart_Szendroedi_Hwang_Roden_Roden_Al-Hasani_et al._2020, title={Early changes in hepatic energy metabolism and lipid content in recent-onset type 1 and 2 diabetes mellitus}, DOI={10.1016/j.jhep.2020.11.030}, journal={Journal of Hepatology}, author={Kupriyanova, Yuliya and Zaharia, Oana Patricia and Bobrov, Pavel and Karusheva, Yanislava and Burkart, Volker and Szendroedi, Julia and Hwang, Jong-Hee and Roden, Michael and Roden, M. and Al-Hasani, H. and et al.}, year={2020}, pages={1028–1037} }' chicago: Kupriyanova, Yuliya, Oana Patricia Zaharia, Pavel Bobrov, Yanislava Karusheva, Volker Burkart, Julia Szendroedi, Jong-Hee Hwang, et al. “Early Changes in Hepatic Energy Metabolism and Lipid Content in Recent-Onset Type 1 and 2 Diabetes Mellitus.” Journal of Hepatology, 2020, 1028–37. https://doi.org/10.1016/j.jhep.2020.11.030. ieee: 'Y. Kupriyanova et al., “Early changes in hepatic energy metabolism and lipid content in recent-onset type 1 and 2 diabetes mellitus,” Journal of Hepatology, pp. 1028–1037, 2020, doi: 10.1016/j.jhep.2020.11.030.' mla: Kupriyanova, Yuliya, et al. “Early Changes in Hepatic Energy Metabolism and Lipid Content in Recent-Onset Type 1 and 2 Diabetes Mellitus.” Journal of Hepatology, 2020, pp. 1028–37, doi:10.1016/j.jhep.2020.11.030. short: Y. Kupriyanova, O.P. Zaharia, P. Bobrov, Y. Karusheva, V. Burkart, J. Szendroedi, J.-H. Hwang, M. Roden, M. Roden, H. Al-Hasani, V. Burkart, A. Buyken, G. Geerling, J.H. Hwang, C. Herder, A. Icks, K. Jandeleit-Dahm, S. Kahl, J. Kotzka, O. Kuss, E. Lammert, S. Trenkamp, W. Rathmann, J. Szendroedi, D. Ziegler, Journal of Hepatology (2020) 1028–1037. date_created: 2021-11-25T12:03:01Z date_updated: 2022-01-06T06:57:45Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.1016/j.jhep.2020.11.030 language: - iso: eng page: 1028-1037 publication: Journal of Hepatology publication_identifier: issn: - 0168-8278 publication_status: published status: public title: Early changes in hepatic energy metabolism and lipid content in recent-onset type 1 and 2 diabetes mellitus type: journal_article user_id: '61597' year: '2020' ... --- _id: '27797' abstract: - lang: eng text: "Abstract\r\n \r\n Objective\r\n \ To provide a systematic overview of world dietary sugar and sugar-sweetened beverage (SSB) intake trends in children and adolescents.\r\n \ \r\n \r\n Data Sources\r\n Medline, Embase, and the Cochrane Central Register of Controlled Trials in the Cochrane Library were searched through January 2019 to identify longitudinal follow-up studies with time-trend data and repeated cross-sectional studies.\r\n \r\n \r\n \ Data Extraction\r\n Data from studies reporting ≥ 2 measurements (sugars, SSB, or sweets/candy) over ≥ 2 years and included ≥ 20 healthy, normal- or overweight children or adolescents aged 1–19 years.\r\n \r\n \r\n \ Data Analysis\r\n Data from 43 articles (n = 4 prospective cohort studies; n = 39 repeated cross-sectional studies) from 15 countries (n = 8 European countries plus Australia, Canada, China, South Korea, Mexico, Russia, and the United States) are presented narratively. According to the risk of bias in nonrandomized studies of interventions tool, 34 studies were judged to have a moderate risk of bias, and 5 to have a serious risk of bias.\r\n \r\n \r\n \ Conclusions\r\n Consumption among US children and adolescents increased substantially in the decades preceding 2000, followed by a faster and continued decline. As a whole, other international intake trends did not reveal drastic increases and decreases in SSB and dietary sugars; they tended to change only slightly across 3 decades.\r\n " author: - first_name: Karen full_name: Della Corte, Karen last_name: Della Corte - first_name: Jessica full_name: Fife, Jessica last_name: Fife - first_name: Alexis full_name: Gardner, Alexis last_name: Gardner - first_name: Britta L full_name: Murphy, Britta L last_name: Murphy - first_name: Linda full_name: Kleis, Linda last_name: Kleis - first_name: Dennis full_name: Della Corte, Dennis last_name: Della Corte - first_name: Lukas full_name: Schwingshackl, Lukas last_name: Schwingshackl - first_name: James D full_name: LeCheminant, James D last_name: LeCheminant - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken citation: ama: 'Della Corte K, Fife J, Gardner A, et al. World trends in sugar-sweetened beverage and dietary sugar intakes in children and adolescents: a systematic review. Nutrition Reviews. Published online 2020:274-288. doi:10.1093/nutrit/nuaa070' apa: 'Della Corte, K., Fife, J., Gardner, A., Murphy, B. L., Kleis, L., Della Corte, D., Schwingshackl, L., LeCheminant, J. D., & Buyken, A. (2020). World trends in sugar-sweetened beverage and dietary sugar intakes in children and adolescents: a systematic review. Nutrition Reviews, 274–288. https://doi.org/10.1093/nutrit/nuaa070' bibtex: '@article{Della Corte_Fife_Gardner_Murphy_Kleis_Della Corte_Schwingshackl_LeCheminant_Buyken_2020, title={World trends in sugar-sweetened beverage and dietary sugar intakes in children and adolescents: a systematic review}, DOI={10.1093/nutrit/nuaa070}, journal={Nutrition Reviews}, author={Della Corte, Karen and Fife, Jessica and Gardner, Alexis and Murphy, Britta L and Kleis, Linda and Della Corte, Dennis and Schwingshackl, Lukas and LeCheminant, James D and Buyken, Anette}, year={2020}, pages={274–288} }' chicago: 'Della Corte, Karen, Jessica Fife, Alexis Gardner, Britta L Murphy, Linda Kleis, Dennis Della Corte, Lukas Schwingshackl, James D LeCheminant, and Anette Buyken. “World Trends in Sugar-Sweetened Beverage and Dietary Sugar Intakes in Children and Adolescents: A Systematic Review.” Nutrition Reviews, 2020, 274–88. https://doi.org/10.1093/nutrit/nuaa070.' ieee: 'K. Della Corte et al., “World trends in sugar-sweetened beverage and dietary sugar intakes in children and adolescents: a systematic review,” Nutrition Reviews, pp. 274–288, 2020, doi: 10.1093/nutrit/nuaa070.' mla: 'Della Corte, Karen, et al. “World Trends in Sugar-Sweetened Beverage and Dietary Sugar Intakes in Children and Adolescents: A Systematic Review.” Nutrition Reviews, 2020, pp. 274–88, doi:10.1093/nutrit/nuaa070.' short: K. Della Corte, J. Fife, A. Gardner, B.L. Murphy, L. Kleis, D. Della Corte, L. Schwingshackl, J.D. LeCheminant, A. Buyken, Nutrition Reviews (2020) 274–288. date_created: 2021-11-25T12:04:06Z date_updated: 2022-01-06T06:57:45Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.1093/nutrit/nuaa070 language: - iso: eng page: 274-288 publication: Nutrition Reviews publication_identifier: issn: - 0029-6643 - 1753-4887 publication_status: published status: public title: 'World trends in sugar-sweetened beverage and dietary sugar intakes in children and adolescents: a systematic review' type: journal_article user_id: '61597' year: '2020' ... --- _id: '27799' abstract: - lang: eng text: Dietary fibre is a generic term describing non-absorbed plant carbohydrates and small amounts of associated non-carbohydrate components. The main contributors of fibre to the diet are the cell walls of plant tissues, which are supramolecular polymer networks containing variable proportions of cellulose, hemicelluloses, pectic substances, and non-carbohydrate components, such as lignin. Other contributors of fibre are the intracellular storage oligosaccharides, such as fructans. A distinction needs to be made between intrinsic sources of dietary fibre and purified forms of fibre, given that the three-dimensional matrix of the plant cell wall confers benefits beyond fibre isolates. Movement through the digestive tract modifies the cell wall structure and may affect the interactions with the colonic microbes (e.g., small intestinally non-absorbed carbohydrates are broken down by bacteria to short-chain fatty acids, absorbed by colonocytes). These aspects, combined with the fibre associated components (e.g., micronutrients, polyphenols, phytosterols, and phytoestrogens), may contribute to the health outcomes seen with the consumption of dietary fibre. Therefore, where possible, processing should minimise the degradation of the plant cell wall structures to preserve some of its benefits. Food labelling should include dietary fibre values and distinguish between intrinsic and added fibre. Labelling may also help achieve the recommended intake of 14 g/1000 kcal/day. article_number: '2553' author: - first_name: Livia S. A. full_name: Augustin, Livia S. A. last_name: Augustin - first_name: Anne-Marie full_name: Aas, Anne-Marie last_name: Aas - first_name: Arnie full_name: Astrup, Arnie last_name: Astrup - first_name: Fiona S. full_name: Atkinson, Fiona S. last_name: Atkinson - first_name: Sara full_name: Baer-Sinnott, Sara last_name: Baer-Sinnott - first_name: Alan W. full_name: Barclay, Alan W. last_name: Barclay - first_name: Jennie C. full_name: Brand-Miller, Jennie C. last_name: Brand-Miller - first_name: Furio full_name: Brighenti, Furio last_name: Brighenti - first_name: Monica full_name: Bullo, Monica last_name: Bullo - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Antonio full_name: Ceriello, Antonio last_name: Ceriello - first_name: Peter R. full_name: Ellis, Peter R. last_name: Ellis - first_name: Marie-Ann full_name: Ha, Marie-Ann last_name: Ha - first_name: Jeyakumar C. full_name: Henry, Jeyakumar C. last_name: Henry - first_name: Cyril W. C. full_name: Kendall, Cyril W. C. last_name: Kendall - first_name: Carlo full_name: La Vecchia, Carlo last_name: La Vecchia - first_name: Simin full_name: Liu, Simin last_name: Liu - first_name: Geoffrey full_name: Livesey, Geoffrey last_name: Livesey - first_name: Andrea full_name: Poli, Andrea last_name: Poli - first_name: Jordi full_name: Salas-Salvadó, Jordi last_name: Salas-Salvadó - first_name: Gabriele full_name: Riccardi, Gabriele last_name: Riccardi - first_name: Ulf full_name: Riserus, Ulf last_name: Riserus - first_name: Salwa W. full_name: Rizkalla, Salwa W. last_name: Rizkalla - first_name: John L. full_name: Sievenpiper, John L. last_name: Sievenpiper - first_name: Antonia full_name: Trichopoulou, Antonia last_name: Trichopoulou - first_name: Kathy full_name: Usic, Kathy last_name: Usic - first_name: Thomas M. S. full_name: Wolever, Thomas M. S. last_name: Wolever - first_name: Walter C. full_name: Willett, Walter C. last_name: Willett - first_name: David J. A. full_name: Jenkins, David J. A. last_name: Jenkins citation: ama: Augustin LSA, Aas A-M, Astrup A, et al. Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC). Nutrients. Published online 2020. doi:10.3390/nu12092553 apa: Augustin, L. S. A., Aas, A.-M., Astrup, A., Atkinson, F. S., Baer-Sinnott, S., Barclay, A. W., Brand-Miller, J. C., Brighenti, F., Bullo, M., Buyken, A., Ceriello, A., Ellis, P. R., Ha, M.-A., Henry, J. C., Kendall, C. W. C., La Vecchia, C., Liu, S., Livesey, G., Poli, A., … Jenkins, D. J. A. (2020). Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC). Nutrients, Article 2553. https://doi.org/10.3390/nu12092553 bibtex: '@article{Augustin_Aas_Astrup_Atkinson_Baer-Sinnott_Barclay_Brand-Miller_Brighenti_Bullo_Buyken_et al._2020, title={Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC)}, DOI={10.3390/nu12092553}, number={2553}, journal={Nutrients}, author={Augustin, Livia S. A. and Aas, Anne-Marie and Astrup, Arnie and Atkinson, Fiona S. and Baer-Sinnott, Sara and Barclay, Alan W. and Brand-Miller, Jennie C. and Brighenti, Furio and Bullo, Monica and Buyken, Anette and et al.}, year={2020} }' chicago: Augustin, Livia S. A., Anne-Marie Aas, Arnie Astrup, Fiona S. Atkinson, Sara Baer-Sinnott, Alan W. Barclay, Jennie C. Brand-Miller, et al. “Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC).” Nutrients, 2020. https://doi.org/10.3390/nu12092553. ieee: 'L. S. A. Augustin et al., “Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC),” Nutrients, Art. no. 2553, 2020, doi: 10.3390/nu12092553.' mla: Augustin, Livia S. A., et al. “Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC).” Nutrients, 2553, 2020, doi:10.3390/nu12092553. short: L.S.A. Augustin, A.-M. Aas, A. Astrup, F.S. Atkinson, S. Baer-Sinnott, A.W. Barclay, J.C. Brand-Miller, F. Brighenti, M. Bullo, A. Buyken, A. Ceriello, P.R. Ellis, M.-A. Ha, J.C. Henry, C.W.C. Kendall, C. La Vecchia, S. Liu, G. Livesey, A. Poli, J. Salas-Salvadó, G. Riccardi, U. Riserus, S.W. Rizkalla, J.L. Sievenpiper, A. Trichopoulou, K. Usic, T.M.S. Wolever, W.C. Willett, D.J.A. Jenkins, Nutrients (2020). date_created: 2021-11-25T12:08:46Z date_updated: 2022-01-06T06:57:45Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.3390/nu12092553 language: - iso: eng publication: Nutrients publication_identifier: issn: - 2072-6643 publication_status: published status: public title: Dietary Fibre Consensus from the International Carbohydrate Quality Consortium (ICQC) type: journal_article user_id: '61597' year: '2020' ... --- _id: '27800' abstract: - lang: eng text: A lower 24-h urine pH (24h-pH), i.e., a higher renal excretion of free protons, at a given acid load to the body, denotes a reduction in the kidney’s capacity for net acid excretion (NAE). There is increasing evidence, not only for patients with type 2 diabetes but also for healthy individuals, that higher body fatness or waist circumference (WC) has a negative impact on renal function to excrete acids (NAE). We hypothesized that adiposity-related inflammation molecules might mediate this relation between adiposity and renal acid excretion function. Twelve biomarkers of inflammation were measured in fasting blood samples from 162 adult participants (18–25 yr old) of the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study who had undergone anthropometric measurements and collected 24-h urine samples. Both Baron and Kenny’s (B&K’s) steps to test mediation and causal mediation analysis were conducted to examine the potential mediatory roles of biomarkers of inflammation in the WC-24-h pH relationship after strictly controlling for laboratory-measured NAE. In B&K’s mediation analysis, leptin, soluble intercellular adhesion molecule 1 (sICAM-1), and adiponectin significantly associated with the outcome 24-h pH and attenuated the WC-pH relation. In agreement herewith, causal mediation analysis estimated the “natural indirect effects” of WC on 24-h pH via leptin ( P = 0.01) and adiponectin ( P = 0.03) to be significant, with a trend for sICAM-1 ( P = 0.09). The calculated proportions mediated by leptin, adiponectin, and sICAM-1 were 64%, 23%, and 12%, respectively. Both mediation analyses identified an inflammatory cytokine (leptin) and an anti-inflammatory cytokine (adiponectin) along with sICAM-1 as being potentially involved in mediating adiposity-related influences on renal acid excretion capacity. author: - first_name: Yifan full_name: Hua, Yifan last_name: Hua - first_name: Christian full_name: Herder, Christian last_name: Herder - first_name: Hermann full_name: Kalhoff, Hermann last_name: Kalhoff - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Jonas full_name: Esche, Jonas last_name: Esche - first_name: Danika full_name: Krupp, Danika last_name: Krupp - first_name: Stefan A. full_name: Wudy, Stefan A. last_name: Wudy - first_name: Thomas full_name: Remer, Thomas last_name: Remer citation: ama: 'Hua Y, Herder C, Kalhoff H, et al. Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1. American Journal of Physiology-Renal Physiology. Published online 2020:F469-F475. doi:10.1152/ajprenal.00257.2020' apa: 'Hua, Y., Herder, C., Kalhoff, H., Buyken, A., Esche, J., Krupp, D., Wudy, S. A., & Remer, T. (2020). Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1. American Journal of Physiology-Renal Physiology, F469–F475. https://doi.org/10.1152/ajprenal.00257.2020' bibtex: '@article{Hua_Herder_Kalhoff_Buyken_Esche_Krupp_Wudy_Remer_2020, title={Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1}, DOI={10.1152/ajprenal.00257.2020}, journal={American Journal of Physiology-Renal Physiology}, author={Hua, Yifan and Herder, Christian and Kalhoff, Hermann and Buyken, Anette and Esche, Jonas and Krupp, Danika and Wudy, Stefan A. and Remer, Thomas}, year={2020}, pages={F469–F475} }' chicago: 'Hua, Yifan, Christian Herder, Hermann Kalhoff, Anette Buyken, Jonas Esche, Danika Krupp, Stefan A. Wudy, and Thomas Remer. “Inflammatory Mediators in the Adipo-Renal Axis: Leptin, Adiponectin, and Soluble ICAM-1.” American Journal of Physiology-Renal Physiology, 2020, F469–75. https://doi.org/10.1152/ajprenal.00257.2020.' ieee: 'Y. Hua et al., “Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1,” American Journal of Physiology-Renal Physiology, pp. F469–F475, 2020, doi: 10.1152/ajprenal.00257.2020.' mla: 'Hua, Yifan, et al. “Inflammatory Mediators in the Adipo-Renal Axis: Leptin, Adiponectin, and Soluble ICAM-1.” American Journal of Physiology-Renal Physiology, 2020, pp. F469–75, doi:10.1152/ajprenal.00257.2020.' short: Y. Hua, C. Herder, H. Kalhoff, A. Buyken, J. Esche, D. Krupp, S.A. Wudy, T. Remer, American Journal of Physiology-Renal Physiology (2020) F469–F475. date_created: 2021-11-25T12:09:30Z date_updated: 2022-01-06T06:57:45Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.1152/ajprenal.00257.2020 language: - iso: eng page: F469-F475 publication: American Journal of Physiology-Renal Physiology publication_identifier: issn: - 1931-857X - 1522-1466 publication_status: published status: public title: 'Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1' type: journal_article user_id: '61597' year: '2020' ... --- _id: '27801' article_number: e0233227 author: - first_name: Juliana full_name: Nyasordzi, Juliana last_name: Nyasordzi - first_name: Katharina full_name: Penczynski, Katharina last_name: Penczynski - first_name: Thomas full_name: Remer, Thomas last_name: Remer - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken citation: ama: Nyasordzi J, Penczynski K, Remer T, Buyken A. Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood. PLOS ONE. Published online 2020. doi:10.1371/journal.pone.0233227 apa: Nyasordzi, J., Penczynski, K., Remer, T., & Buyken, A. (2020). Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood. PLOS ONE, Article e0233227. https://doi.org/10.1371/journal.pone.0233227 bibtex: '@article{Nyasordzi_Penczynski_Remer_Buyken_2020, title={Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood}, DOI={10.1371/journal.pone.0233227}, number={e0233227}, journal={PLOS ONE}, author={Nyasordzi, Juliana and Penczynski, Katharina and Remer, Thomas and Buyken, Anette}, year={2020} }' chicago: Nyasordzi, Juliana, Katharina Penczynski, Thomas Remer, and Anette Buyken. “Early Life Factors and Their Relevance to Intima-Media Thickness of the Common Carotid Artery in Early Adulthood.” PLOS ONE, 2020. https://doi.org/10.1371/journal.pone.0233227. ieee: 'J. Nyasordzi, K. Penczynski, T. Remer, and A. Buyken, “Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood,” PLOS ONE, Art. no. e0233227, 2020, doi: 10.1371/journal.pone.0233227.' mla: Nyasordzi, Juliana, et al. “Early Life Factors and Their Relevance to Intima-Media Thickness of the Common Carotid Artery in Early Adulthood.” PLOS ONE, e0233227, 2020, doi:10.1371/journal.pone.0233227. short: J. Nyasordzi, K. Penczynski, T. Remer, A. Buyken, PLOS ONE (2020). date_created: 2021-11-25T12:10:22Z date_updated: 2022-01-06T06:57:45Z department: - _id: '17' - _id: '22' - _id: '571' doi: 10.1371/journal.pone.0233227 language: - iso: eng publication: PLOS ONE publication_identifier: issn: - 1932-6203 publication_status: published status: public title: Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood type: journal_article user_id: '61597' year: '2020' ...