@article{23615,
  abstract     = {{<p>Realization of extreme fast charging (XFC, ≤15 minutes) of lithium-ion batteries is imperative for the widespread adoption of electric vehicles.</p>}},
  author       = {{Paul, Partha P. and Thampy, Vivek and Cao, Chuntian and Steinrück, Hans-Georg and Tanim, Tanvir R. and Dunlop, Alison R. and Dufek, Eric J. and Trask, Stephen E. and Jansen, Andrew N. and Toney, Michael F. and Nelson Weker, Johanna}},
  issn         = {{1754-5692}},
  journal      = {{Energy & Environmental Science}},
  pages        = {{4979--4988}},
  title        = {{{Quantification of heterogeneous, irreversible lithium plating in extreme fast charging of lithium-ion batteries}}},
  doi          = {{10.1039/d1ee01216a}},
  volume       = {{14}},
  year         = {{2021}},
}

@article{23616,
  author       = {{Galluzzo, Michael D. and Grundy, Lorena S. and Takacs, Christopher J. and Cao, Chuntian and Steinrück, Hans-Georg and Fu, Sean and Rivas Valadez, Michael A. and Toney, Michael F. and Balsara, Nitash P.}},
  issn         = {{0024-9297}},
  journal      = {{Macromolecules}},
  pages        = {{7808--7824}},
  title        = {{{Orientation-Dependent Distortion of Lamellae in a Block Copolymer Electrolyte under DC Polarization}}},
  doi          = {{10.1021/acs.macromol.1c01295}},
  volume       = {{54}},
  year         = {{2021}},
}

@article{22636,
  abstract     = {{<jats:p>The effects that solid–liquid interfaces exert on the aggregation of proteins and peptides are of high relevance for various fields of basic and applied research, ranging from molecular biology and biomedicine to nanotechnology. While the influence of surface chemistry has received a lot of attention in this context, the role of surface topography has mostly been neglected so far. In this work, therefore, we investigate the aggregation of the type 2 diabetes-associated peptide hormone hIAPP in contact with flat and nanopatterned silicon oxide surfaces. The nanopatterned surfaces are produced by ion beam irradiation, resulting in well-defined anisotropic ripple patterns with heights and periodicities of about 1.5 and 30 nm, respectively. Using time-lapse atomic force microscopy, the morphology of the hIAPP aggregates is characterized quantitatively. Aggregation results in both amorphous aggregates and amyloid fibrils, with the presence of the nanopatterns leading to retarded fibrillization and stronger amorphous aggregation. This is attributed to structural differences in the amorphous aggregates formed at the nanopatterned surface, which result in a lower propensity for nucleating amyloid fibrillization. Our results demonstrate that nanoscale surface topography may modulate peptide and protein aggregation pathways in complex and intricate ways.</jats:p>}},
  author       = {{Hanke, Marcel and Yang, Yu and Ji, Yuxin and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{1422-0067}},
  journal      = {{International Journal of Molecular Sciences}},
  pages        = {{5142}},
  title        = {{{Nanoscale Surface Topography Modulates hIAPP Aggregation Pathways at Solid–Liquid Interfaces}}},
  doi          = {{10.3390/ijms22105142}},
  volume       = {{22}},
  year         = {{2021}},
}

@article{22637,
  abstract     = {{<jats:title>Abstract</jats:title>
               <jats:p>Doxorubicin (DOX) is a common drug in cancer chemotherapy, and its high DNA-binding affinity can be harnessed in preparing DOX-loaded DNA nanostructures for targeted delivery and therapeutics. Although DOX has been widely studied, the existing literature of DOX-loaded DNA-carriers remains limited and incoherent. Here, based on an in-depth spectroscopic analysis, we characterize and optimize the DOX loading into different 2D and 3D scaffolded DNA origami nanostructures (DONs). In our experimental conditions, all DONs show similar DOX binding capacities (one DOX molecule per two to three base pairs), and the binding equilibrium is reached within seconds, remarkably faster than previously acknowledged. To characterize drug release profiles, DON degradation and DOX release from the complexes upon DNase I digestion was studied. For the employed DONs, the relative doses (DOX molecules released per unit time) may vary by two orders of magnitude depending on the DON superstructure. In addition, we identify DOX aggregation mechanisms and spectral changes linked to pH, magnesium, and DOX concentration. These features have been largely ignored in experimenting with DNA nanostructures, but are probably the major sources of the incoherence of the experimental results so far. Therefore, we believe this work can act as a guide to tailoring the release profiles and developing better drug delivery systems based on DNA-carriers.</jats:p>}},
  author       = {{Ijäs, Heini and Shen, Boxuan and Heuer-Jungemann, Amelie and Keller, Adrian and Kostiainen, Mauri A and Liedl, Tim and Ihalainen, Janne A and Linko, Veikko}},
  issn         = {{0305-1048}},
  journal      = {{Nucleic Acids Research}},
  pages        = {{3048--3062}},
  title        = {{{Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release}}},
  doi          = {{10.1093/nar/gkab097}},
  volume       = {{49}},
  year         = {{2021}},
}

@article{22638,
  author       = {{Xin, Y and Shen, B and Kostiainen, MA and Grundmeier, Guido and Castro, M and Linko, V and Keller, Adrian}},
  issn         = {{0947-6539}},
  journal      = {{Chemistry – A European Journal}},
  number       = {{33}},
  pages        = {{8564--8571}},
  title        = {{{Scaling Up DNA Origami Lattice Assembly.}}},
  doi          = {{10.1002/chem.202100784}},
  volume       = {{27}},
  year         = {{2021}},
}

@article{22639,
  author       = {{Yang, Y and Knust, S and Schwiderek, S and Qin, Q and Yun, Q and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2079-4991}},
  journal      = {{Nanomaterials}},
  number       = {{2}},
  pages        = {{ 357 }},
  title        = {{{Protein Adsorption at Nanorough Titanium Oxide Surfaces: The Importance of Surface Statistical Parameters beyond Surface Roughness.}}},
  doi          = {{10.3390/nano11020357}},
  volume       = {{11}},
  year         = {{2021}},
}

@article{22640,
  author       = {{Piskunen, Petteri and Shen, Boxuan and Keller, Adrian and Toppari, J. Jussi and Kostiainen, Mauri A. and Linko, Veikko}},
  issn         = {{2574-0970}},
  journal      = {{ACS Applied Nano Materials}},
  pages        = {{529--538}},
  title        = {{{Biotemplated Lithography of Inorganic Nanostructures (BLIN) for Versatile Patterning of Functional Materials}}},
  doi          = {{10.1021/acsanm.0c02849}},
  volume       = {{4}},
  year         = {{2021}},
}

@article{22641,
  author       = {{Smith, DM and Keller, Adrian}},
  issn         = {{2699-9307}},
  journal      = {{Advanced NanoBiomed Research}},
  pages        = {{2000049}},
  title        = {{{DNA Nanostructures in the Fight Against Infectious Diseases.}}},
  doi          = {{10.1002/anbr.202000049}},
  volume       = {{1}},
  year         = {{2021}},
}

@article{22642,
  author       = {{Xin, Y and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2699-9307}},
  journal      = {{Advanced NanoBiomed Research}},
  number       = {{2}},
  pages        = {{2170023}},
  title        = {{{Adsorption of SARS-CoV-2 Spike Protein S1 at Oxide Surfaces Studied by High-Speed Atomic Force Microscopy.}}},
  doi          = {{10.1002/anbr.202170023}},
  volume       = {{1}},
  year         = {{2021}},
}

@article{22643,
  author       = {{Yang, Yu and Yu, Mingrui and Böke, Frederik and Qin, Qin and Hübner, René and Knust, Steffen and Schwiderek, Sabrina and Grundmeier, Guido and Fischer, Horst and Keller, Adrian}},
  issn         = {{0169-4332}},
  journal      = {{Applied Surface Science}},
  pages        = {{147671}},
  title        = {{{Effect of nanoscale surface topography on the adsorption of globular proteins}}},
  doi          = {{10.1016/j.apsusc.2020.147671}},
  volume       = {{535}},
  year         = {{2021}},
}

@article{22688,
  author       = {{Meinderink, Dennis and Kielar, C. and Sobol, O. and Ruhm, L. and Rieker, F. and Nolkemper, K. and Orive, A.G. and Ozcan, O. and Grundmeier, Guido}},
  issn         = {{0143-7496}},
  journal      = {{International Journal of Adhesion and Adhesives}},
  title        = {{{Effect of PAA-induced surface etching on the adhesion properties of ZnO nanostructured films}}},
  doi          = {{10.1016/j.ijadhadh.2021.102812}},
  year         = {{2021}},
}

@article{22697,
  author       = {{Knust, Steffen and Ruhm, Lukas and Kuhlmann, Andreas and Meinderink, Dennis and Bürger, Julius and Lindner, Jörg K. N. and Arcos de Pedro, Maria Teresa and Grundmeier, Guido}},
  issn         = {{0377-0486}},
  journal      = {{Journal of Raman Spectroscopy}},
  pages        = {{1237--1245}},
  title        = {{{In situ backside Raman spectroscopy of zinc oxide nanorods in an atmospheric‐pressure dielectric barrier discharge plasma}}},
  doi          = {{10.1002/jrs.6123}},
  year         = {{2021}},
}

@article{22773,
  abstract     = {{<jats:p>Ion beam irradiation of solid surfaces may result in the self-organized formation of well-defined topographic nanopatterns. Depending on the irradiation conditions and the material properties, isotropic or anisotropic patterns of differently shaped features may be obtained. Most intriguingly, the periodicities of these patterns can be adjusted in the range between less than twenty and several hundred nanometers, which covers the dimensions of many cellular and extracellular features. However, even though ion beam nanopatterning has been studied for several decades and is nowadays widely employed in the fabrication of functional surfaces, it has found its way into the biomaterials field only recently. This review provides a brief overview of the basics of ion beam nanopatterning, emphasizes aspects of particular relevance for biomaterials applications, and summarizes a number of recent studies that investigated the effects of such nanopatterned surfaces on the adsorption of biomolecules and the response of adhering cells. Finally, promising future directions and potential translational challenges are identified.</jats:p>}},
  author       = {{Yang, Yu and Keller, Adrian}},
  issn         = {{2076-3417}},
  journal      = {{Applied Sciences}},
  pages        = {{6575}},
  title        = {{{Ion Beam Nanopatterning of Biomaterial Surfaces}}},
  doi          = {{10.3390/app11146575}},
  volume       = {{11}},
  year         = {{2021}},
}

@article{22926,
  abstract     = {{<jats:p>Implant-associated infections are an increasingly severe burden on healthcare systems worldwide and many research activities currently focus on inhibiting microbial colonization of biomedically relevant surfaces. To obtain molecular-level understanding of the involved processes and interactions, we investigate the adsorption of synthetic adhesin-like peptide sequences derived from the type IV pili of the Pseudomonas aeruginosa strains PAK and PAO at abiotic model surfaces, i.e., Au, SiO2, and oxidized Ti. These peptides correspond to the sequences of the receptor-binding domain 128–144 of the major pilin protein, which is known to facilitate P. aeruginosa adhesion at biotic and abiotic surfaces. Using quartz crystal microbalance with dissipation monitoring (QCM-D), we find that peptide adsorption is material- as well as strain-dependent. At the Au surface, PAO(128–144) shows drastically stronger adsorption than PAK(128–144), whereas adsorption of both peptides is markedly reduced at the oxide surfaces with less drastic differences between the two sequences. These observations suggest that peptide adsorption is influenced by not only the peptide sequence, but also peptide conformation. Our results furthermore highlight the importance of molecular-level investigations to understand and ultimately control microbial colonization of surfaces.</jats:p>}},
  author       = {{Yang, Yu and Schwiderek, Sabrina and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2673-8023}},
  journal      = {{Micro}},
  number       = {{1}},
  pages        = {{129--139}},
  title        = {{{Strain-Dependent Adsorption of Pseudomonas aeruginosa-Derived Adhesin-like Peptides at Abiotic Surfaces}}},
  doi          = {{10.3390/micro1010010}},
  volume       = {{1}},
  year         = {{2021}},
}

@article{23023,
  abstract     = {{<jats:p>DNA origami nanostructures (DONs) are promising substrates for the single-molecule investigation of biomolecular reactions and dynamics by in situ atomic force microscopy (AFM). For this, they are typically immobilized on mica substrates by adding millimolar concentrations of Mg2+ ions to the sample solution, which enable the adsorption of the negatively charged DONs at the like-charged mica surface. These non-physiological Mg2+ concentrations, however, present a serious limitation in such experiments as they may interfere with the reactions and processes under investigation. Therefore, we here evaluate three approaches to efficiently immobilize DONs at mica surfaces under essentially Mg2+-free conditions. These approaches rely on the pre-adsorption of different multivalent cations, i.e., Ni2+, poly-l-lysine (PLL), and spermidine (Spdn). DON adsorption is studied in phosphate-buffered saline (PBS) and pure water. In general, Ni2+ shows the worst performance with heavily deformed DONs. For 2D DON triangles, adsorption at PLL- and in particular Spdn-modified mica may outperform even Mg2+-mediated adsorption in terms of surface coverage, depending on the employed solution. For 3D six-helix bundles, less pronounced differences between the individual strategies are observed. Our results provide some general guidance for the immobilization of DONs at mica surfaces under Mg2+-free conditions and may aid future in situ AFM studies.</jats:p>}},
  author       = {{Xin, Yang and Zargariantabrizi, Amir Ardalan and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{1420-3049}},
  journal      = {{Molecules}},
  pages        = {{4798}},
  title        = {{{Magnesium-Free Immobilization of DNA Origami Nanostructures at Mica Surfaces for Atomic Force Microscopy}}},
  doi          = {{10.3390/molecules26164798}},
  volume       = {{26}},
  year         = {{2021}},
}

@inproceedings{21717,
  author       = {{Schmolke, Tobias and Teutenberg, Dominik and Meschut, Gerson and Meinderink, Dennis and Koch, Leon  and Ebbert, Christoph and Grundmeier, Guido}},
  location     = {{Online Event}},
  title        = {{{Entwicklung einer Methode zur Bewertung einer stahlintensiven Mischbau-Klebverbindung eines Batteriegehäuses gegenüber mechanischer und medialer Belastung und Berücksichtigung der Interphasenstruktur}}},
  year         = {{2021}},
}

@article{34647,
  author       = {{Brögelmann, T and Bobzin, K and Grundmeier, Guido and de los Arcos, T and Kruppe, N C and Schwiderek, S and Carlet, M}},
  issn         = {{0022-3727}},
  journal      = {{Journal of Physics D: Applied Physics}},
  keywords     = {{Surfaces, Coatings and Films, Acoustics and Ultrasonics, Condensed Matter Physics, Electronic, Optical and Magnetic Materials}},
  number       = {{3}},
  publisher    = {{IOP Publishing}},
  title        = {{{Durability of nanolayer Ti–Al–O–N hard coatings under simulated polycarbonate melt processing conditions}}},
  doi          = {{10.1088/1361-6463/ac2e31}},
  volume       = {{55}},
  year         = {{2021}},
}

@article{34645,
  author       = {{Tripathi, Tripurari Sharan and Wilken, Martin and Hoppe, Christian and de los Arcos, Teresa and Grundmeier, Guido and Devi, Anjana and Karppinen, Maarit}},
  issn         = {{1438-1656}},
  journal      = {{Advanced Engineering Materials}},
  keywords     = {{Condensed Matter Physics, General Materials Science}},
  number       = {{10}},
  publisher    = {{Wiley}},
  title        = {{{Atomic Layer Deposition of Copper Metal Films from Cu(acac)            <sub>2</sub>            and Hydroquinone Reductant}}},
  doi          = {{10.1002/adem.202100446}},
  volume       = {{23}},
  year         = {{2021}},
}

@article{22538,
  author       = {{de los Arcos de Pedro, Maria Teresa and Müller, Hendrik and Wang, Fuzeng and Damerla, Varun Raj and Hoppe, Christian and Weinberger, Christian and Tiemann, Michael and Grundmeier, Guido}},
  issn         = {{0924-2031}},
  journal      = {{Vibrational Spectroscopy}},
  title        = {{{Review of infrared spectroscopy techniques for the determination of internal structure in thin SiO2 films}}},
  doi          = {{10.1016/j.vibspec.2021.103256}},
  year         = {{2021}},
}

@article{22539,
  author       = {{Bobzin, K. and Kalscheuer, C. and Grundmeier, G. and de los Arcos de Pedro, Maria Teresa and Schwiderek, S. and Carlet, M.}},
  issn         = {{0257-8972}},
  journal      = {{Surface and Coatings Technology}},
  title        = {{{Design of a TiAlON multilayer coating: Oxidation stability and deformation behavior}}},
  doi          = {{10.1016/j.surfcoat.2021.127417}},
  year         = {{2021}},
}