---
_id: '63675'
abstract:
- lang: eng
text: Cobalt spinel (Co3O4) catalysts are widely studied in scope of the electrocatalytic
oxygen evolution reaction (OER), yet the role of interfacial structural transformation
under anodic bias remains under debate. Here, we employ an operando approach,
combining a fast electrochemical quartz crystal microbalance with dissipation
monitoring (EQCM-D), electrochemical impedance spectroscopy (EIS), and Raman spectroscopy
to investigate interfacial transformations of Co3O4 nanoparticle electrodes in
alkaline electrolyte. We identify two distinct regimes during the anodic sweep
prior to the macroscopic OER onset. At lower potentials, the catalyst interface
remains mechanically rigid while reversibly associating several OH−/H2O species
per oxidized cobalt site. At higher potentials, pronounced softening of the interface
occurs alongside further uptake of electrolyte species. This indicates amorphization
and a ‘swelling process’ beyond simple adsorption. Notably, an electrochemical
conditioning treatment can suppress mass and compliance hysteresis without affecting
OER activity, suggesting that most incorporated electrolyte species do not participate
in the OER. EIS further reveals that OER intermediates form well below the apparent
OER onset potential. These results advance our mechanistic understanding of interfacial
transformations in cobalt-based OER catalysts and establish EQCM-D as a sensitive
operando technique for probing electrocatalyst transformations.
article_number: e01104
author:
- first_name: Christian
full_name: Leppin, Christian
id: '117722'
last_name: Leppin
- first_name: Carsten
full_name: Placke‐Yan, Carsten
last_name: Placke‐Yan
- first_name: Georg
full_name: Bendt, Georg
last_name: Bendt
- first_name: Sheila
full_name: Hernandez, Sheila
last_name: Hernandez
- first_name: Kristina
full_name: Tschulik, Kristina
last_name: Tschulik
- first_name: Stephan
full_name: Schulz, Stephan
last_name: Schulz
- first_name: Julia
full_name: Linnemann, Julia
id: '116779'
last_name: Linnemann
orcid: 0000-0001-6883-5424
citation:
ama: 'Leppin C, Placke‐Yan C, Bendt G, et al. Interfacial Softening and Electrolyte
Uptake in Co3O4 OER Catalysts: Insight from Operando
Spectroscopy and Fast EQCM‐D. ChemCatChem. 2026;18(2). doi:10.1002/cctc.202501104'
apa: 'Leppin, C., Placke‐Yan, C., Bendt, G., Hernandez, S., Tschulik, K., Schulz,
S., & Linnemann, J. (2026). Interfacial Softening and Electrolyte Uptake in
Co3O4 OER Catalysts: Insight from Operando Spectroscopy
and Fast EQCM‐D. ChemCatChem, 18(2), Article e01104. https://doi.org/10.1002/cctc.202501104'
bibtex: '@article{Leppin_Placke‐Yan_Bendt_Hernandez_Tschulik_Schulz_Linnemann_2026,
title={Interfacial Softening and Electrolyte Uptake in Co3O4
OER Catalysts: Insight from Operando Spectroscopy and Fast EQCM‐D}, volume={18},
DOI={10.1002/cctc.202501104},
number={2e01104}, journal={ChemCatChem}, publisher={Wiley}, author={Leppin, Christian
and Placke‐Yan, Carsten and Bendt, Georg and Hernandez, Sheila and Tschulik, Kristina
and Schulz, Stephan and Linnemann, Julia}, year={2026} }'
chicago: 'Leppin, Christian, Carsten Placke‐Yan, Georg Bendt, Sheila Hernandez,
Kristina Tschulik, Stephan Schulz, and Julia Linnemann. “Interfacial Softening
and Electrolyte Uptake in Co3O4 OER Catalysts: Insight from
Operando Spectroscopy and Fast EQCM‐D.” ChemCatChem 18, no. 2 (2026).
https://doi.org/10.1002/cctc.202501104.'
ieee: 'C. Leppin et al., “Interfacial Softening and Electrolyte Uptake in
Co3O4 OER Catalysts: Insight from Operando Spectroscopy
and Fast EQCM‐D,” ChemCatChem, vol. 18, no. 2, Art. no. e01104, 2026, doi:
10.1002/cctc.202501104.'
mla: 'Leppin, Christian, et al. “Interfacial Softening and Electrolyte Uptake in
Co3O4 OER Catalysts: Insight from Operando Spectroscopy
and Fast EQCM‐D.” ChemCatChem, vol. 18, no. 2, e01104, Wiley, 2026, doi:10.1002/cctc.202501104.'
short: C. Leppin, C. Placke‐Yan, G. Bendt, S. Hernandez, K. Tschulik, S. Schulz,
J. Linnemann, ChemCatChem 18 (2026).
date_created: 2026-01-20T19:33:40Z
date_updated: 2026-01-20T19:36:51Z
department:
- _id: '985'
doi: 10.1002/cctc.202501104
intvolume: ' 18'
issue: '2'
keyword:
- electrocatalysis
- Co3O4
- EQCM-D
- OER
language:
- iso: eng
main_file_link:
- open_access: '1'
oa: '1'
publication: ChemCatChem
publication_identifier:
issn:
- 1867-3880
- 1867-3899
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: 'Interfacial Softening and Electrolyte Uptake in Co3O4
OER Catalysts: Insight from Operando Spectroscopy and Fast EQCM‐D'
type: journal_article
user_id: '116779'
volume: 18
year: '2026'
...
---
_id: '64182'
abstract:
- lang: eng
text: Overcoming the slow kinetics of the oxygen evolution reaction at the anode
is a key challenge for the production of hydrogen via electrolysis. This reaction
operates at very positive potentials, where the electrocatalyst is exposed to
highly oxidative conditions and prone to potential-dependent transformation of
the near-surface region. While substantial evidence for such surface restructuring
exists, its extent and relevance for the catalyst’s activity are unclear. We address
this topic for the case of Co3O4, one of the best-known electrocatalysts exhibiting
surface restructuring, by studies of epitaxial (111)-ordered electrodeposited
films with combined operando X-ray surface diffraction and absorption spectroscopy,
electrochemical impedance spectroscopy, and electrochemical measurements on rotating
disk electrodes. Comparison of the as-prepared and annealed state of the same
samples, which both are stable even under long-term oxygen evolution conditions,
provides clear insight into the role of surface defects. Our results show that
defect-free annealed Co3O4(111) surfaces are structurally stable over a wide potential
range and hydroxylate via adsorption at surface oxygen and Co sites. Potential-induced
surface restructuring of the Co3O4 lattice occurs only in the presence of surface
defects, leading to the formation of the well-known nanometer-thick oxyhydroxide
skin layer. The presence of this skin layer promotes oxygen evolution at low overpotentials
but results in higher Tafel slopes. As a result, highly ordered Co3O4(111) surfaces
are more active at high current densities than defective Co3O4 surfaces that undergo
surface restructuring. These results highlight that strategies for catalyst surface
defect engineering need to be application-oriented.
article_number: acscatal.5c08785
article_type: original
author:
- first_name: Carl Hendric
full_name: Scharf, Carl Hendric
last_name: Scharf
- first_name: Alex
full_name: Chandraraj, Alex
last_name: Chandraraj
- first_name: Konrad
full_name: Dyk, Konrad
last_name: Dyk
- first_name: Felix
full_name: Stebner, Felix
last_name: Stebner
- first_name: Sören
full_name: Lepin, Sören
last_name: Lepin
- first_name: Jing
full_name: Tian, Jing
last_name: Tian
- first_name: Laila
full_name: El Bergmi Byaz, Laila
last_name: El Bergmi Byaz
- first_name: Jochim
full_name: Stettner, Jochim
last_name: Stettner
- first_name: Christian
full_name: Leppin, Christian
id: '117722'
last_name: Leppin
- first_name: Anastasiia
full_name: Kotova, Anastasiia
last_name: Kotova
- first_name: Sebastian
full_name: Reinke, Sebastian
id: '117727'
last_name: Reinke
- first_name: Julia
full_name: Linnemann, Julia
id: '116779'
last_name: Linnemann
orcid: 0000-0001-6883-5424
- first_name: Fouad
full_name: Maroun, Fouad
last_name: Maroun
- first_name: Olaf M.
full_name: Magnussen, Olaf M.
last_name: Magnussen
citation:
ama: Scharf CH, Chandraraj A, Dyk K, et al. Role of Defects in Reversible Surface
Restructuring and Activity of Co3O4 Oxygen Evolution Electrocatalysts.
ACS Catalysis. Published online 2026. doi:10.1021/acscatal.5c08785
apa: Scharf, C. H., Chandraraj, A., Dyk, K., Stebner, F., Lepin, S., Tian, J., El
Bergmi Byaz, L., Stettner, J., Leppin, C., Kotova, A., Reinke, S., Linnemann,
J., Maroun, F., & Magnussen, O. M. (2026). Role of Defects in Reversible Surface
Restructuring and Activity of Co3O4 Oxygen Evolution Electrocatalysts.
ACS Catalysis, Article acscatal.5c08785. https://doi.org/10.1021/acscatal.5c08785
bibtex: '@article{Scharf_Chandraraj_Dyk_Stebner_Lepin_Tian_El Bergmi Byaz_Stettner_Leppin_Kotova_et
al._2026, title={Role of Defects in Reversible Surface Restructuring and Activity
of Co3O4 Oxygen Evolution Electrocatalysts}, DOI={10.1021/acscatal.5c08785},
number={acscatal.5c08785}, journal={ACS Catalysis}, publisher={American Chemical
Society (ACS)}, author={Scharf, Carl Hendric and Chandraraj, Alex and Dyk, Konrad
and Stebner, Felix and Lepin, Sören and Tian, Jing and El Bergmi Byaz, Laila and
Stettner, Jochim and Leppin, Christian and Kotova, Anastasiia and et al.}, year={2026}
}'
chicago: Scharf, Carl Hendric, Alex Chandraraj, Konrad Dyk, Felix Stebner, Sören
Lepin, Jing Tian, Laila El Bergmi Byaz, et al. “Role of Defects in Reversible
Surface Restructuring and Activity of Co3O4 Oxygen Evolution
Electrocatalysts.” ACS Catalysis, 2026. https://doi.org/10.1021/acscatal.5c08785.
ieee: 'C. H. Scharf et al., “Role of Defects in Reversible Surface Restructuring
and Activity of Co3O4 Oxygen Evolution Electrocatalysts,”
ACS Catalysis, Art. no. acscatal.5c08785, 2026, doi: 10.1021/acscatal.5c08785.'
mla: Scharf, Carl Hendric, et al. “Role of Defects in Reversible Surface Restructuring
and Activity of Co3O4 Oxygen Evolution Electrocatalysts.”
ACS Catalysis, acscatal.5c08785, American Chemical Society (ACS), 2026,
doi:10.1021/acscatal.5c08785.
short: C.H. Scharf, A. Chandraraj, K. Dyk, F. Stebner, S. Lepin, J. Tian, L. El
Bergmi Byaz, J. Stettner, C. Leppin, A. Kotova, S. Reinke, J. Linnemann, F. Maroun,
O.M. Magnussen, ACS Catalysis (2026).
date_created: 2026-02-16T14:22:15Z
date_updated: 2026-02-16T14:25:00Z
department:
- _id: '985'
doi: 10.1021/acscatal.5c08785
keyword:
- electrocatalysis
- oxygen evolution reaction
- cobalt spinel
- operando characterization
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://pubs.acs.org/doi/10.1021/acscatal.5c08785
oa: '1'
publication: ACS Catalysis
publication_identifier:
issn:
- 2155-5435
- 2155-5435
publication_status: published
publisher: American Chemical Society (ACS)
quality_controlled: '1'
status: public
title: Role of Defects in Reversible Surface Restructuring and Activity of Co3O4
Oxygen Evolution Electrocatalysts
type: journal_article
user_id: '116779'
year: '2026'
...
---
_id: '63436'
article_number: acsanm.5c04857
author:
- first_name: Sivoney Ferreira
full_name: de Souza, Sivoney Ferreira
last_name: de Souza
- first_name: Christina
full_name: Beresowski, Christina
last_name: Beresowski
- first_name: Sabine
full_name: Kosmella, Sabine
last_name: Kosmella
- first_name: João
full_name: Ameixa, João
last_name: Ameixa
- first_name: Bhanu Kiran
full_name: Pothineni, Bhanu Kiran
last_name: Pothineni
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Matthias
full_name: Hartlieb, Matthias
last_name: Hartlieb
- first_name: Andreas
full_name: Taubert, Andreas
last_name: Taubert
- first_name: Ilko
full_name: Bald, Ilko
last_name: Bald
citation:
ama: de Souza SF, Beresowski C, Kosmella S, et al. Nanocellulose Membranes for Plasmon-Enhanced
Removal of Organic Pollutants from Water. ACS Applied Nano Materials. Published
online 2026. doi:10.1021/acsanm.5c04857
apa: de Souza, S. F., Beresowski, C., Kosmella, S., Ameixa, J., Pothineni, B. K.,
Keller, A. C., Hartlieb, M., Taubert, A., & Bald, I. (2026). Nanocellulose
Membranes for Plasmon-Enhanced Removal of Organic Pollutants from Water. ACS
Applied Nano Materials, Article acsanm.5c04857. https://doi.org/10.1021/acsanm.5c04857
bibtex: '@article{de Souza_Beresowski_Kosmella_Ameixa_Pothineni_Keller_Hartlieb_Taubert_Bald_2026,
title={Nanocellulose Membranes for Plasmon-Enhanced Removal of Organic Pollutants
from Water}, DOI={10.1021/acsanm.5c04857},
number={acsanm.5c04857}, journal={ACS Applied Nano Materials}, publisher={American
Chemical Society (ACS)}, author={de Souza, Sivoney Ferreira and Beresowski, Christina
and Kosmella, Sabine and Ameixa, João and Pothineni, Bhanu Kiran and Keller, Adrian
Clemens and Hartlieb, Matthias and Taubert, Andreas and Bald, Ilko}, year={2026}
}'
chicago: Souza, Sivoney Ferreira de, Christina Beresowski, Sabine Kosmella, João
Ameixa, Bhanu Kiran Pothineni, Adrian Clemens Keller, Matthias Hartlieb, Andreas
Taubert, and Ilko Bald. “Nanocellulose Membranes for Plasmon-Enhanced Removal
of Organic Pollutants from Water.” ACS Applied Nano Materials, 2026. https://doi.org/10.1021/acsanm.5c04857.
ieee: 'S. F. de Souza et al., “Nanocellulose Membranes for Plasmon-Enhanced
Removal of Organic Pollutants from Water,” ACS Applied Nano Materials,
Art. no. acsanm.5c04857, 2026, doi: 10.1021/acsanm.5c04857.'
mla: de Souza, Sivoney Ferreira, et al. “Nanocellulose Membranes for Plasmon-Enhanced
Removal of Organic Pollutants from Water.” ACS Applied Nano Materials,
acsanm.5c04857, American Chemical Society (ACS), 2026, doi:10.1021/acsanm.5c04857.
short: S.F. de Souza, C. Beresowski, S. Kosmella, J. Ameixa, B.K. Pothineni, A.C.
Keller, M. Hartlieb, A. Taubert, I. Bald, ACS Applied Nano Materials (2026).
date_created: 2026-01-05T08:23:24Z
date_updated: 2026-01-05T08:23:51Z
department:
- _id: '302'
doi: 10.1021/acsanm.5c04857
language:
- iso: eng
publication: ACS Applied Nano Materials
publication_identifier:
issn:
- 2574-0970
- 2574-0970
publication_status: published
publisher: American Chemical Society (ACS)
status: public
title: Nanocellulose Membranes for Plasmon-Enhanced Removal of Organic Pollutants
from Water
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '62726'
abstract:
- lang: eng
text: Surface-assisted DNA lattice assembly is used in the synthesis of
functional surfaces and as a model of supramolecular network formation. Here,
competitive DNA binding of different cation species is investigated...
author:
- first_name: Xiaodan
full_name: Xu, Xiaodan
last_name: Xu
- first_name: Bhanu Kiran
full_name: Pothineni, Bhanu Kiran
last_name: Pothineni
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Satoru
full_name: Tsushima, Satoru
last_name: Tsushima
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Xu X, Pothineni BK, Grundmeier G, Tsushima S, Keller AC. On the role of cation-DNA
interactions in surface-assisted DNA lattice assembly. Nanoscale. Published
online 2026. doi:10.1039/d5nr03695j
apa: Xu, X., Pothineni, B. K., Grundmeier, G., Tsushima, S., & Keller, A. C.
(2026). On the role of cation-DNA interactions in surface-assisted DNA lattice
assembly. Nanoscale. https://doi.org/10.1039/d5nr03695j
bibtex: '@article{Xu_Pothineni_Grundmeier_Tsushima_Keller_2026, title={On the role
of cation-DNA interactions in surface-assisted DNA lattice assembly}, DOI={10.1039/d5nr03695j}, journal={Nanoscale},
publisher={Royal Society of Chemistry (RSC)}, author={Xu, Xiaodan and Pothineni,
Bhanu Kiran and Grundmeier, Guido and Tsushima, Satoru and Keller, Adrian Clemens},
year={2026} }'
chicago: Xu, Xiaodan, Bhanu Kiran Pothineni, Guido Grundmeier, Satoru Tsushima,
and Adrian Clemens Keller. “On the Role of Cation-DNA Interactions in Surface-Assisted
DNA Lattice Assembly.” Nanoscale, 2026. https://doi.org/10.1039/d5nr03695j.
ieee: 'X. Xu, B. K. Pothineni, G. Grundmeier, S. Tsushima, and A. C. Keller, “On
the role of cation-DNA interactions in surface-assisted DNA lattice assembly,”
Nanoscale, 2026, doi: 10.1039/d5nr03695j.'
mla: Xu, Xiaodan, et al. “On the Role of Cation-DNA Interactions in Surface-Assisted
DNA Lattice Assembly.” Nanoscale, Royal Society of Chemistry (RSC), 2026,
doi:10.1039/d5nr03695j.
short: X. Xu, B.K. Pothineni, G. Grundmeier, S. Tsushima, A.C. Keller, Nanoscale
(2026).
date_created: 2025-12-01T13:48:42Z
date_updated: 2026-01-06T10:42:32Z
department:
- _id: '302'
doi: 10.1039/d5nr03695j
language:
- iso: eng
publication: Nanoscale
publication_identifier:
issn:
- 2040-3364
- 2040-3372
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: On the role of cation-DNA interactions in surface-assisted DNA lattice assembly
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '64982'
author:
- first_name: Kai
full_name: Lingnau, Kai
last_name: Lingnau
- first_name: Chantal
full_name: Theile-Rasche, Chantal
last_name: Theile-Rasche
- first_name: Klaus
full_name: Vissing, Klaus
last_name: Vissing
- first_name: Elmar
full_name: Moritzer, Elmar
id: '20531'
last_name: Moritzer
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Martin
full_name: Wiesing, Martin
last_name: Wiesing
citation:
ama: Lingnau K, Theile-Rasche C, Vissing K, Moritzer E, Grundmeier G, Wiesing M.
Mechanisms of deposit formation in injection moulding cavities and the role of
tool coatings and internal release agents. Surface and Coatings Technology.
2026;524:133280. doi:10.1016/j.surfcoat.2026.133280
apa: Lingnau, K., Theile-Rasche, C., Vissing, K., Moritzer, E., Grundmeier, G.,
& Wiesing, M. (2026). Mechanisms of deposit formation in injection moulding
cavities and the role of tool coatings and internal release agents. Surface
and Coatings Technology, 524, 133280. https://doi.org/10.1016/j.surfcoat.2026.133280
bibtex: '@article{Lingnau_Theile-Rasche_Vissing_Moritzer_Grundmeier_Wiesing_2026,
title={Mechanisms of deposit formation in injection moulding cavities and the
role of tool coatings and internal release agents}, volume={524}, DOI={10.1016/j.surfcoat.2026.133280},
journal={Surface and Coatings Technology}, author={Lingnau, Kai and Theile-Rasche,
Chantal and Vissing, Klaus and Moritzer, Elmar and Grundmeier, Guido and Wiesing,
Martin}, year={2026}, pages={133280} }'
chicago: 'Lingnau, Kai, Chantal Theile-Rasche, Klaus Vissing, Elmar Moritzer, Guido
Grundmeier, and Martin Wiesing. “Mechanisms of Deposit Formation in Injection
Moulding Cavities and the Role of Tool Coatings and Internal Release Agents.”
Surface and Coatings Technology 524 (2026): 133280. https://doi.org/10.1016/j.surfcoat.2026.133280.'
ieee: 'K. Lingnau, C. Theile-Rasche, K. Vissing, E. Moritzer, G. Grundmeier, and
M. Wiesing, “Mechanisms of deposit formation in injection moulding cavities and
the role of tool coatings and internal release agents,” Surface and Coatings
Technology, vol. 524, p. 133280, 2026, doi: 10.1016/j.surfcoat.2026.133280.'
mla: Lingnau, Kai, et al. “Mechanisms of Deposit Formation in Injection Moulding
Cavities and the Role of Tool Coatings and Internal Release Agents.” Surface
and Coatings Technology, vol. 524, 2026, p. 133280, doi:10.1016/j.surfcoat.2026.133280.
short: K. Lingnau, C. Theile-Rasche, K. Vissing, E. Moritzer, G. Grundmeier, M.
Wiesing, Surface and Coatings Technology 524 (2026) 133280.
date_created: 2026-03-16T12:20:48Z
date_updated: 2026-03-16T12:51:54Z
department:
- _id: '9'
- _id: '367'
- _id: '302'
doi: 10.1016/j.surfcoat.2026.133280
extern: '1'
intvolume: ' 524'
keyword:
- Plasmabeschichtung
- Spritzgießen
- Spritzgießwerkzeug
- Trennschicht
- ultraTrenn
- Werkzeugbeschichtung
language:
- iso: eng
page: '133280'
publication: Surface and Coatings Technology
publication_identifier:
issn:
- '02578972'
quality_controlled: '1'
status: public
title: Mechanisms of deposit formation in injection moulding cavities and the role
of tool coatings and internal release agents
type: journal_article
user_id: '59363'
volume: 524
year: '2026'
...
---
_id: '65082'
abstract:
- lang: eng
text: Encoding information in molecular arrangements on DNA origami nanostructures
(DONs) provides the basis for novel concepts in molecular data storage and computing.
To preserve their integrity over long timescales, the information‐carrying DONs
are often stored in a frozen state. Here, we investigate the effect of repeated
freeze–thaw (F/T) cycles on the structural and functional integrity of DONs carrying
biotin (Bt) modifications. Streptavidin (SAv) binding is used to visualize the
stored information by atomic force microscopy (AFM) before and after 40 F/T cycles.
Two strategies are compared by F/T cycling of (I) SAv‐bound DONs and (II) SAv‐free
DONs that are exposed to SAv directly before AFM imaging. Our results reveal that
while the DONs retain their overall shape, F/T cycling induces a small amount
of damage, leading to slightly reduced SAv binding. Adding glycerol at mM concentrations
efficiently protects the DONs and restores the original SAv binding yields. Nevertheless,
SAv exposure after F/T cycling leads to slightly higher and more consistent SAv
binding yields and a lower background of nonspecifically adsorbed SAv compared
to Strategy I. This makes information readout by AFM more efficient and renders
Strategy II more convenient for long‐term storage of information‐carrying DONs
with repeated information readout.
article_number: e202500161
author:
- first_name: Xinyang
full_name: Li, Xinyang
last_name: Li
- first_name: Lukas
full_name: Rabbe, Lukas
last_name: Rabbe
- first_name: Jacqueline
full_name: Linneweber, Jacqueline
last_name: Linneweber
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Li X, Rabbe L, Linneweber J, Grundmeier G, Keller AC. Stability of Information‐Carrying
DNA Origami Nanostructures During Repeated Freeze–Thaw Cycles. Chemistry–Methods.
2026;6(3). doi:10.1002/cmtd.202500161
apa: Li, X., Rabbe, L., Linneweber, J., Grundmeier, G., & Keller, A. C. (2026).
Stability of Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw
Cycles. Chemistry–Methods, 6(3), Article e202500161. https://doi.org/10.1002/cmtd.202500161
bibtex: '@article{Li_Rabbe_Linneweber_Grundmeier_Keller_2026, title={Stability of
Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw Cycles},
volume={6}, DOI={10.1002/cmtd.202500161},
number={3e202500161}, journal={Chemistry–Methods}, publisher={Wiley}, author={Li,
Xinyang and Rabbe, Lukas and Linneweber, Jacqueline and Grundmeier, Guido and
Keller, Adrian Clemens}, year={2026} }'
chicago: Li, Xinyang, Lukas Rabbe, Jacqueline Linneweber, Guido Grundmeier, and
Adrian Clemens Keller. “Stability of Information‐Carrying DNA Origami Nanostructures
During Repeated Freeze–Thaw Cycles.” Chemistry–Methods 6, no. 3 (2026).
https://doi.org/10.1002/cmtd.202500161.
ieee: 'X. Li, L. Rabbe, J. Linneweber, G. Grundmeier, and A. C. Keller, “Stability
of Information‐Carrying DNA Origami Nanostructures During Repeated Freeze–Thaw
Cycles,” Chemistry–Methods, vol. 6, no. 3, Art. no. e202500161, 2026, doi:
10.1002/cmtd.202500161.'
mla: Li, Xinyang, et al. “Stability of Information‐Carrying DNA Origami Nanostructures
During Repeated Freeze–Thaw Cycles.” Chemistry–Methods, vol. 6, no. 3,
e202500161, Wiley, 2026, doi:10.1002/cmtd.202500161.
short: X. Li, L. Rabbe, J. Linneweber, G. Grundmeier, A.C. Keller, Chemistry–Methods
6 (2026).
date_created: 2026-03-23T07:12:13Z
date_updated: 2026-03-23T07:12:53Z
department:
- _id: '302'
doi: 10.1002/cmtd.202500161
intvolume: ' 6'
issue: '3'
language:
- iso: eng
publication: Chemistry–Methods
publication_identifier:
issn:
- 2628-9725
- 2628-9725
publication_status: published
publisher: Wiley
status: public
title: Stability of Information‐Carrying DNA Origami Nanostructures During Repeated
Freeze–Thaw Cycles
type: journal_article
user_id: '48864'
volume: 6
year: '2026'
...
---
_id: '65108'
abstract:
- lang: eng
text: "Abstract\r\n Lithographic
surface patterning is a cornerstone of modern materials and device fabrication.
Although the available lithography techniques are constantly being advanced to
push the feature sizes down to the few-nanometer scale, such developments are
associated with many technological and economic challenges. Combining established
top-down lithography with bottom-up self-assembly strategies has the potential
to overcome those challenges and enable the manipulation of matter with molecular
precision. One of the most exciting approaches in this regard is to harness the
programmability of DNA self-assembly to create precise DNA nanostructure masks
to be used in the lithographic patterning of diverse substrates. DNA nanotechnology
has provided us with a versatile toolbox for the high-yield synthesis of 2D and
3D nanostructures with complex, user-defined shapes at unprecedented molecular
accuracy. Consequently, the last decade has seen intense research efforts aimed
at transferring such DNA nanostructure shapes into functional organic and inorganic
materials and we have now arrived at a point where sophisticated molecular lithography
approaches utilize DNA nanostructure masks for the fabrication of plasmonic surfaces
for metamaterials and sensing applications. This review summarizes how the spatial
information of such DNA nanostructure masks can be transferred into various organic
and inorganic materials through selective etching and deposition steps. The review
also discusses recent developments toward all-purpose molecular lithography schemes
and highlights promising extensions of the discussed methods toward new materials
systems and application fields."
author:
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Veikko
full_name: Linko, Veikko
last_name: Linko
citation:
ama: 'Keller AC, Linko V. Molecular lithography with DNA nanostructures: Methods
and applications. Journal of Physics D: Applied Physics. Published online
2026. doi:10.1088/1361-6463/ae5667'
apa: 'Keller, A. C., & Linko, V. (2026). Molecular lithography with DNA nanostructures:
Methods and applications. Journal of Physics D: Applied Physics. https://doi.org/10.1088/1361-6463/ae5667'
bibtex: '@article{Keller_Linko_2026, title={Molecular lithography with DNA nanostructures:
Methods and applications}, DOI={10.1088/1361-6463/ae5667},
journal={Journal of Physics D: Applied Physics}, publisher={IOP Publishing}, author={Keller,
Adrian Clemens and Linko, Veikko}, year={2026} }'
chicago: 'Keller, Adrian Clemens, and Veikko Linko. “Molecular Lithography with
DNA Nanostructures: Methods and Applications.” Journal of Physics D: Applied
Physics, 2026. https://doi.org/10.1088/1361-6463/ae5667.'
ieee: 'A. C. Keller and V. Linko, “Molecular lithography with DNA nanostructures:
Methods and applications,” Journal of Physics D: Applied Physics, 2026,
doi: 10.1088/1361-6463/ae5667.'
mla: 'Keller, Adrian Clemens, and Veikko Linko. “Molecular Lithography with DNA
Nanostructures: Methods and Applications.” Journal of Physics D: Applied Physics,
IOP Publishing, 2026, doi:10.1088/1361-6463/ae5667.'
short: 'A.C. Keller, V. Linko, Journal of Physics D: Applied Physics (2026).'
date_created: 2026-03-25T07:43:24Z
date_updated: 2026-03-25T07:44:52Z
department:
- _id: '302'
doi: 10.1088/1361-6463/ae5667
language:
- iso: eng
publication: 'Journal of Physics D: Applied Physics'
publication_identifier:
issn:
- 0022-3727
- 1361-6463
publication_status: published
publisher: IOP Publishing
status: public
title: 'Molecular lithography with DNA nanostructures: Methods and applications'
type: journal_article
user_id: '48864'
year: '2026'
...
---
_id: '65490'
abstract:
- lang: eng
text: In recent years, nanostructures assembled by DNA have found promising
applications in optics, medicine, and sensing. DNA origami in particular provides
unique self‐assembly properties, not only enabling a vast variety of functionalization
schemes but also presenting a promising route to fabricate large‐scale, bottom‐up
nanostructured arrays. This approach has comparable precision to electron beam
lithography but avoids slow and expensive patterning steps. However, self‐assembly
of lattices with high order and well‐defined periodicity requires careful tuning
of the deposition parameters and interactions involved, which has been done mostly
on mica so far. As mica is not compatible with standard microfabrication processes,
we investigate here the assembly of DNA origami lattices on the most general microfabrication
material, that is, silicon wafers, which has turned out to be rather challenging.
We study how the forming of polycrystalline 2D‐fishnet‐type lattices is influenced
by different incubation conditions and strengths of the origami–origami and origami‐surface
interactions, with the aim to create large‐scale single‐crystalline lattices.
The lattices are characterized by atomic force microscopy and analyzed for precision
of formation, achievable domain size, and surface coverage of well‐formed lattices.
Thanks to the silicon substrate, these DNA origami lattices can be further combined
with traditional microfabrication processes to turn them, for example, into metamaterials
with novel optical properties.
article_number: e202500813
author:
- first_name: Heini
full_name: Järvinen, Heini
last_name: Järvinen
- first_name: Johannes M.
full_name: Parikka, Johannes M.
last_name: Parikka
- first_name: R. P. Thiwangi N.
full_name: Rajapaksha, R. P. Thiwangi N.
last_name: Rajapaksha
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: J. Jussi
full_name: Toppari, J. Jussi
last_name: Toppari
citation:
ama: Järvinen H, Parikka JM, Rajapaksha RPTN, Keller AC, Toppari JJ. Towards Single‐Crystalline
DNA Origami Lattices on Silicon Wafers for Bottom‐Up Nanofabrication. Small
Structures. 2026;7(4). doi:10.1002/sstr.202500813
apa: Järvinen, H., Parikka, J. M., Rajapaksha, R. P. T. N., Keller, A. C., &
Toppari, J. J. (2026). Towards Single‐Crystalline DNA Origami Lattices on Silicon
Wafers for Bottom‐Up Nanofabrication. Small Structures, 7(4), Article
e202500813. https://doi.org/10.1002/sstr.202500813
bibtex: '@article{Järvinen_Parikka_Rajapaksha_Keller_Toppari_2026, title={Towards
Single‐Crystalline DNA Origami Lattices on Silicon Wafers for Bottom‐Up Nanofabrication},
volume={7}, DOI={10.1002/sstr.202500813},
number={4e202500813}, journal={Small Structures}, publisher={Wiley}, author={Järvinen,
Heini and Parikka, Johannes M. and Rajapaksha, R. P. Thiwangi N. and Keller, Adrian
Clemens and Toppari, J. Jussi}, year={2026} }'
chicago: Järvinen, Heini, Johannes M. Parikka, R. P. Thiwangi N. Rajapaksha, Adrian
Clemens Keller, and J. Jussi Toppari. “Towards Single‐Crystalline DNA Origami
Lattices on Silicon Wafers for Bottom‐Up Nanofabrication.” Small Structures
7, no. 4 (2026). https://doi.org/10.1002/sstr.202500813.
ieee: 'H. Järvinen, J. M. Parikka, R. P. T. N. Rajapaksha, A. C. Keller, and J.
J. Toppari, “Towards Single‐Crystalline DNA Origami Lattices on Silicon Wafers
for Bottom‐Up Nanofabrication,” Small Structures, vol. 7, no. 4, Art. no.
e202500813, 2026, doi: 10.1002/sstr.202500813.'
mla: Järvinen, Heini, et al. “Towards Single‐Crystalline DNA Origami Lattices on
Silicon Wafers for Bottom‐Up Nanofabrication.” Small Structures, vol. 7,
no. 4, e202500813, Wiley, 2026, doi:10.1002/sstr.202500813.
short: H. Järvinen, J.M. Parikka, R.P.T.N. Rajapaksha, A.C. Keller, J.J. Toppari,
Small Structures 7 (2026).
date_created: 2026-04-22T16:17:08Z
date_updated: 2026-04-22T16:17:22Z
department:
- _id: '302'
doi: 10.1002/sstr.202500813
intvolume: ' 7'
issue: '4'
language:
- iso: eng
publication: Small Structures
publication_identifier:
issn:
- 2688-4062
- 2688-4062
publication_status: published
publisher: Wiley
status: public
title: Towards Single‐Crystalline DNA Origami Lattices on Silicon Wafers for Bottom‐Up
Nanofabrication
type: journal_article
user_id: '48864'
volume: 7
year: '2026'
...
---
_id: '59421'
author:
- first_name: Johannes
full_name: Parikka, Johannes
last_name: Parikka
- first_name: Bhanu Kiran
full_name: Pothineni, Bhanu Kiran
last_name: Pothineni
- first_name: Heini
full_name: Järvinen, Heini
last_name: Järvinen
- first_name: Kosti
full_name: Tapio, Kosti
last_name: Tapio
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: J. Jussi
full_name: Toppari, J. Jussi
last_name: Toppari
citation:
ama: 'Parikka J, Pothineni BK, Järvinen H, Tapio K, Keller A, Toppari JJ. Surface-Assisted
Assembly of DNA Origami Lattices on Silicon Wafers. In: Methods in Molecular
Biology. Springer US; 2025. doi:10.1007/978-1-0716-4394-5_7'
apa: Parikka, J., Pothineni, B. K., Järvinen, H., Tapio, K., Keller, A., & Toppari,
J. J. (2025). Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers.
In Methods in Molecular Biology. Springer US. https://doi.org/10.1007/978-1-0716-4394-5_7
bibtex: '@inbook{Parikka_Pothineni_Järvinen_Tapio_Keller_Toppari_2025, place={New
York, NY}, title={Surface-Assisted Assembly of DNA Origami Lattices on Silicon
Wafers}, DOI={10.1007/978-1-0716-4394-5_7},
booktitle={Methods in Molecular Biology}, publisher={Springer US}, author={Parikka,
Johannes and Pothineni, Bhanu Kiran and Järvinen, Heini and Tapio, Kosti and Keller,
Adrian and Toppari, J. Jussi}, year={2025} }'
chicago: 'Parikka, Johannes, Bhanu Kiran Pothineni, Heini Järvinen, Kosti Tapio,
Adrian Keller, and J. Jussi Toppari. “Surface-Assisted Assembly of DNA Origami
Lattices on Silicon Wafers.” In Methods in Molecular Biology. New York,
NY: Springer US, 2025. https://doi.org/10.1007/978-1-0716-4394-5_7.'
ieee: 'J. Parikka, B. K. Pothineni, H. Järvinen, K. Tapio, A. Keller, and J. J.
Toppari, “Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers,”
in Methods in Molecular Biology, New York, NY: Springer US, 2025.'
mla: Parikka, Johannes, et al. “Surface-Assisted Assembly of DNA Origami Lattices
on Silicon Wafers.” Methods in Molecular Biology, Springer US, 2025, doi:10.1007/978-1-0716-4394-5_7.
short: 'J. Parikka, B.K. Pothineni, H. Järvinen, K. Tapio, A. Keller, J.J. Toppari,
in: Methods in Molecular Biology, Springer US, New York, NY, 2025.'
date_created: 2025-04-08T09:06:14Z
date_updated: 2025-04-08T09:06:34Z
department:
- _id: '302'
doi: 10.1007/978-1-0716-4394-5_7
language:
- iso: eng
place: New York, NY
publication: Methods in Molecular Biology
publication_identifier:
isbn:
- '9781071643938'
- '9781071643945'
issn:
- 1064-3745
- 1940-6029
publication_status: published
publisher: Springer US
status: public
title: Surface-Assisted Assembly of DNA Origami Lattices on Silicon Wafers
type: book_chapter
user_id: '48864'
year: '2025'
...
---
_id: '59847'
abstract:
- lang: eng
text: "Abstract\r\n The surface-assisted
assembly of DNA origami lattices is a potent method for creating molecular lithography
masks. Lattice quality and assembly kinetics are controlled by various environmental
parameters, including the employed surface, the assembly temperature, and the
ionic composition of the buffer, with optimized parameter combinations resulting
in highly ordered lattices that can span surface areas of several cm2.
Established assembly protocols, however, employ assembly times ranging from hours
to days. Here, the assembly of highly ordered hexagonal DNA origami lattices at
mica surfaces is observed within few minutes using high-speed atomic force microscopy
(HS-AFM). A moderate increase in the DNA origami concentration enables this rapid
assembly. While forming a regular lattice takes 10 min at a DNA origami concentration
of 4 nM, this time is shortened to about 2 min at a concentration of 6 nM. Increasing
the DNA origami concentration any further does not result in shorter assembly
times, presumably because DNA origami arrival at the mica surface is diffusion-limited.
Over short length scales up to 1 µm, lattice order is independent of the DNA origami
concentration. However, at larger length scales of a few microns, a DNA origami
concentration of 10 nM yields slightly better order than lower and higher concentrations.
Therefore, 10 nM can be considered the optimum concentration for the rapid assembly
of highly ordered DNA origami lattices. These results thus represent an important
step toward the industrial-scale application of DNA origami-based lithography
masks."
article_number: '77'
author:
- first_name: Bhanu Kiran
full_name: Pothineni, Bhanu Kiran
last_name: Pothineni
- first_name: Jörg
full_name: Barner, Jörg
last_name: Barner
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: David
full_name: Contreras, David
last_name: Contreras
- first_name: Mario
full_name: Castro, Mario
last_name: Castro
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Pothineni BK, Barner J, Grundmeier G, Contreras D, Castro M, Keller A. Rapid
assembly of highly ordered DNA origami lattices at mica surfaces. Discover
Nano. 2025;20(1). doi:10.1186/s11671-025-04254-2
apa: Pothineni, B. K., Barner, J., Grundmeier, G., Contreras, D., Castro, M., &
Keller, A. (2025). Rapid assembly of highly ordered DNA origami lattices at mica
surfaces. Discover Nano, 20(1), Article 77. https://doi.org/10.1186/s11671-025-04254-2
bibtex: '@article{Pothineni_Barner_Grundmeier_Contreras_Castro_Keller_2025, title={Rapid
assembly of highly ordered DNA origami lattices at mica surfaces}, volume={20},
DOI={10.1186/s11671-025-04254-2},
number={177}, journal={Discover Nano}, publisher={Springer Science and Business
Media LLC}, author={Pothineni, Bhanu Kiran and Barner, Jörg and Grundmeier, Guido
and Contreras, David and Castro, Mario and Keller, Adrian}, year={2025} }'
chicago: Pothineni, Bhanu Kiran, Jörg Barner, Guido Grundmeier, David Contreras,
Mario Castro, and Adrian Keller. “Rapid Assembly of Highly Ordered DNA Origami
Lattices at Mica Surfaces.” Discover Nano 20, no. 1 (2025). https://doi.org/10.1186/s11671-025-04254-2.
ieee: 'B. K. Pothineni, J. Barner, G. Grundmeier, D. Contreras, M. Castro, and A.
Keller, “Rapid assembly of highly ordered DNA origami lattices at mica surfaces,”
Discover Nano, vol. 20, no. 1, Art. no. 77, 2025, doi: 10.1186/s11671-025-04254-2.'
mla: Pothineni, Bhanu Kiran, et al. “Rapid Assembly of Highly Ordered DNA Origami
Lattices at Mica Surfaces.” Discover Nano, vol. 20, no. 1, 77, Springer
Science and Business Media LLC, 2025, doi:10.1186/s11671-025-04254-2.
short: B.K. Pothineni, J. Barner, G. Grundmeier, D. Contreras, M. Castro, A. Keller,
Discover Nano 20 (2025).
date_created: 2025-05-08T07:17:29Z
date_updated: 2025-05-08T07:17:54Z
department:
- _id: '302'
doi: 10.1186/s11671-025-04254-2
intvolume: ' 20'
issue: '1'
language:
- iso: eng
publication: Discover Nano
publication_identifier:
issn:
- 2731-9229
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Rapid assembly of highly ordered DNA origami lattices at mica surfaces
type: journal_article
user_id: '48864'
volume: 20
year: '2025'
...
---
_id: '59992'
abstract:
- lang: eng
text: The immobilization of DNA origami nanostructures on solid surfaces
is an important prerequisite for their application in many biosensors. So far,
DNA origami immobilization has been investigated in detail only...
author:
- first_name: Xiaodan
full_name: Xu, Xiaodan
last_name: Xu
- first_name: Sandra Alicja
full_name: Golebiowska, Sandra Alicja
id: '69524'
last_name: Golebiowska
- first_name: Teresa
full_name: de los Arcos, Teresa
last_name: de los Arcos
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Xu X, Golebiowska SA, de los Arcos T, Grundmeier G, Keller A. DNA origami adsorption
at single-crystalline TiO2 surfaces. RSC Applied Interfaces. Published
online 2025. doi:10.1039/d5lf00109a
apa: Xu, X., Golebiowska, S. A., de los Arcos, T., Grundmeier, G., & Keller,
A. (2025). DNA origami adsorption at single-crystalline TiO2 surfaces. RSC
Applied Interfaces. https://doi.org/10.1039/d5lf00109a
bibtex: '@article{Xu_Golebiowska_de los Arcos_Grundmeier_Keller_2025, title={DNA
origami adsorption at single-crystalline TiO2 surfaces}, DOI={10.1039/d5lf00109a},
journal={RSC Applied Interfaces}, publisher={Royal Society of Chemistry (RSC)},
author={Xu, Xiaodan and Golebiowska, Sandra Alicja and de los Arcos, Teresa and
Grundmeier, Guido and Keller, Adrian}, year={2025} }'
chicago: Xu, Xiaodan, Sandra Alicja Golebiowska, Teresa de los Arcos, Guido Grundmeier,
and Adrian Keller. “DNA Origami Adsorption at Single-Crystalline TiO2 Surfaces.”
RSC Applied Interfaces, 2025. https://doi.org/10.1039/d5lf00109a.
ieee: 'X. Xu, S. A. Golebiowska, T. de los Arcos, G. Grundmeier, and A. Keller,
“DNA origami adsorption at single-crystalline TiO2 surfaces,” RSC Applied Interfaces,
2025, doi: 10.1039/d5lf00109a.'
mla: Xu, Xiaodan, et al. “DNA Origami Adsorption at Single-Crystalline TiO2 Surfaces.”
RSC Applied Interfaces, Royal Society of Chemistry (RSC), 2025, doi:10.1039/d5lf00109a.
short: X. Xu, S.A. Golebiowska, T. de los Arcos, G. Grundmeier, A. Keller, RSC Applied
Interfaces (2025).
date_created: 2025-05-19T09:30:44Z
date_updated: 2025-05-19T09:32:05Z
department:
- _id: '302'
doi: 10.1039/d5lf00109a
language:
- iso: eng
publication: RSC Applied Interfaces
publication_identifier:
issn:
- 2755-3701
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: DNA origami adsorption at single-crystalline TiO2 surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '58613'
abstract:
- lang: eng
text: Self-assembled DNA origami lattices on silicon oxide surfaces have great potential
to serve as masks in molecular lithography. However, silicon oxide surfaces come
in many different forms and the type and history of the silicon oxide has a large
effect on its physicochemical surface properties. Therefore, we here investigate
DNA origami lattice formation on differently fabricated SiOx films on silicon
wafers after wet-chemical oxidation by RCA1. Despite having similar oxide compositions
and hydroxylation states, of all surfaces tested, only thermally grown SiOx performs
similarly well as native oxide. For the other SiOx films deposited by plasma-enhanced
chemical vapor deposition and magnetron sputtering, DNA origami adsorption is
strongly suppressed. This is attributed to an increased surface roughness and
a lower oxide density, respectively. Our results demonstrate that the employed
SiOx surface may decide over the outcome of an experiment and should be considered
as an additional parameter that may require optimization and fine-tuning before
high-quality lattices can be assembled. In particular, our observations suggest
that efficient DNA origami lattice assembly on SiOx surfaces requires a low surface
roughness and a high oxide density.
author:
- first_name: Bhanu Kiran
full_name: Pothineni, Bhanu Kiran
last_name: Pothineni
- first_name: Chantal
full_name: Theile-Rasche, Chantal
last_name: Theile-Rasche
- first_name: Hendrik
full_name: Müller, Hendrik
last_name: Müller
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Maria Teresa
full_name: de los Arcos de Pedro, Maria Teresa
id: '54556'
last_name: de los Arcos de Pedro
orcid: '0000-0002-8684-273X '
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Pothineni BK, Theile-Rasche C, Müller H, Grundmeier G, de los Arcos de Pedro
MT, Keller A. DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces.
Chemistry – A European Journal. Published online 2025:e202404108. doi:10.1002/chem.202404108
apa: Pothineni, B. K., Theile-Rasche, C., Müller, H., Grundmeier, G., de los Arcos
de Pedro, M. T., & Keller, A. (2025). DNA Origami Adsorption and Lattice Formation
on Different SiOx Surfaces. Chemistry – A European Journal, e202404108.
https://doi.org/10.1002/chem.202404108
bibtex: '@article{Pothineni_Theile-Rasche_Müller_Grundmeier_de los Arcos de Pedro_Keller_2025,
title={DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces},
DOI={10.1002/chem.202404108},
journal={Chemistry – A European Journal}, author={Pothineni, Bhanu Kiran and Theile-Rasche,
Chantal and Müller, Hendrik and Grundmeier, Guido and de los Arcos de Pedro, Maria
Teresa and Keller, Adrian}, year={2025}, pages={e202404108} }'
chicago: Pothineni, Bhanu Kiran, Chantal Theile-Rasche, Hendrik Müller, Guido Grundmeier,
Maria Teresa de los Arcos de Pedro, and Adrian Keller. “DNA Origami Adsorption
and Lattice Formation on Different SiOx Surfaces.” Chemistry – A European Journal,
2025, e202404108. https://doi.org/10.1002/chem.202404108.
ieee: 'B. K. Pothineni, C. Theile-Rasche, H. Müller, G. Grundmeier, M. T. de los
Arcos de Pedro, and A. Keller, “DNA Origami Adsorption and Lattice Formation on
Different SiOx Surfaces,” Chemistry – A European Journal, p. e202404108,
2025, doi: 10.1002/chem.202404108.'
mla: Pothineni, Bhanu Kiran, et al. “DNA Origami Adsorption and Lattice Formation
on Different SiOx Surfaces.” Chemistry – A European Journal, 2025, p. e202404108,
doi:10.1002/chem.202404108.
short: B.K. Pothineni, C. Theile-Rasche, H. Müller, G. Grundmeier, M.T. de los Arcos
de Pedro, A. Keller, Chemistry – A European Journal (2025) e202404108.
date_created: 2025-02-12T14:49:48Z
date_updated: 2025-06-10T09:10:16Z
department:
- _id: '302'
doi: 10.1002/chem.202404108
language:
- iso: eng
page: e202404108
publication: Chemistry – A European Journal
status: public
title: DNA Origami Adsorption and Lattice Formation on Different SiOx Surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60082'
author:
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Keller A. DNA origami nanostructures in biomedicine and the issue of stability.
Nucleic Acid Insights. 2025;2(2):61–75. doi:10.18609/nuc.2025.011
apa: Keller, A. (2025). DNA origami nanostructures in biomedicine and the issue
of stability. Nucleic Acid Insights, 2(2), 61–75. https://doi.org/10.18609/nuc.2025.011
bibtex: '@article{Keller_2025, title={DNA origami nanostructures in biomedicine
and the issue of stability}, volume={2}, DOI={10.18609/nuc.2025.011},
number={2}, journal={Nucleic Acid Insights}, author={Keller, Adrian}, year={2025},
pages={61–75} }'
chicago: 'Keller, Adrian. “DNA Origami Nanostructures in Biomedicine and the Issue
of Stability.” Nucleic Acid Insights 2, no. 2 (2025): 61–75. https://doi.org/10.18609/nuc.2025.011.'
ieee: 'A. Keller, “DNA origami nanostructures in biomedicine and the issue of stability,”
Nucleic Acid Insights, vol. 2, no. 2, pp. 61–75, 2025, doi: 10.18609/nuc.2025.011.'
mla: Keller, Adrian. “DNA Origami Nanostructures in Biomedicine and the Issue of
Stability.” Nucleic Acid Insights, vol. 2, no. 2, 2025, pp. 61–75, doi:10.18609/nuc.2025.011.
short: A. Keller, Nucleic Acid Insights 2 (2025) 61–75.
date_created: 2025-06-01T08:53:58Z
date_updated: 2025-06-10T09:09:28Z
ddc:
- '570'
department:
- _id: '302'
doi: 10.18609/nuc.2025.011
file:
- access_level: open_access
content_type: application/pdf
creator: adke
date_created: 2025-06-01T08:53:35Z
date_updated: 2025-06-01T08:53:35Z
file_id: '60083'
file_name: Keller_nai25.pdf
file_size: 701125
relation: main_file
file_date_updated: 2025-06-01T08:53:35Z
has_accepted_license: '1'
intvolume: ' 2'
issue: '2'
language:
- iso: eng
oa: '1'
page: 61–75
publication: Nucleic Acid Insights
status: public
title: DNA origami nanostructures in biomedicine and the issue of stability
type: journal_article
user_id: '48864'
volume: 2
year: '2025'
...
---
_id: '62814'
abstract:
- lang: eng
text: Porous carbons are prominent electrode materials in energy storage applications
such as supercapacitors. However, rational materials development is hampered by
difficulties in interpreting electrochemical impedance spectra (EIS) and drawing
conclusions about promising aspects of device improvement. Here, we characterized
electrodes consisting of activated carbon with polyacrylic acid binder in four
different concentrations of sulfuric acid, using cyclic voltammetry and electrochemical
impedance spectroscopy. Both datasets were evaluated with simple equivalent circuits
and comparatively analyzed. Conductivity of the electrolyte was independently
measured. Cyclic voltammograms (CV) show larger resistance and capacitance at
low scan rates. Resistances obtained from EIS are in good agreement with those
obtained by cyclic voltammograms particularly at high scan rates. The comparison
against specific electrolyte resistance can reveal whether resistances within
the solid electrode architecture or resistances within the electrolyte, partially
confined by pores, are the dominant cause of increased resistance at low scan
rate. Comparison between CV and EIS points to the main electrode capacitance being
described by a constant phase element (CPE) used to fit the low-frequency region
of EIS.
author:
- first_name: Sebastian
full_name: Reinke, Sebastian
id: '117727'
last_name: Reinke
- first_name: Vera
full_name: Khamitsevich, Vera
last_name: Khamitsevich
- first_name: Julia
full_name: Linnemann, Julia
id: '116779'
last_name: Linnemann
orcid: 0000-0001-6883-5424
citation:
ama: 'Reinke S, Khamitsevich V, Linnemann J. Complementary Analysis of Cyclic Voltammograms
and Impedance Spectra of Porous Carbon Electrodes. In: 2024 International Workshop
on Impedance Spectroscopy (IWIS). IEEE; 2025. doi:10.1109/iwis63047.2024.10847115'
apa: Reinke, S., Khamitsevich, V., & Linnemann, J. (2025). Complementary Analysis
of Cyclic Voltammograms and Impedance Spectra of Porous Carbon Electrodes. 2024
International Workshop on Impedance Spectroscopy (IWIS). https://doi.org/10.1109/iwis63047.2024.10847115
bibtex: '@inproceedings{Reinke_Khamitsevich_Linnemann_2025, title={Complementary
Analysis of Cyclic Voltammograms and Impedance Spectra of Porous Carbon Electrodes},
DOI={10.1109/iwis63047.2024.10847115},
booktitle={2024 International Workshop on Impedance Spectroscopy (IWIS)}, publisher={IEEE},
author={Reinke, Sebastian and Khamitsevich, Vera and Linnemann, Julia}, year={2025}
}'
chicago: Reinke, Sebastian, Vera Khamitsevich, and Julia Linnemann. “Complementary
Analysis of Cyclic Voltammograms and Impedance Spectra of Porous Carbon Electrodes.”
In 2024 International Workshop on Impedance Spectroscopy (IWIS). IEEE,
2025. https://doi.org/10.1109/iwis63047.2024.10847115.
ieee: 'S. Reinke, V. Khamitsevich, and J. Linnemann, “Complementary Analysis of
Cyclic Voltammograms and Impedance Spectra of Porous Carbon Electrodes,” 2025,
doi: 10.1109/iwis63047.2024.10847115.'
mla: Reinke, Sebastian, et al. “Complementary Analysis of Cyclic Voltammograms and
Impedance Spectra of Porous Carbon Electrodes.” 2024 International Workshop
on Impedance Spectroscopy (IWIS), IEEE, 2025, doi:10.1109/iwis63047.2024.10847115.
short: 'S. Reinke, V. Khamitsevich, J. Linnemann, in: 2024 International Workshop
on Impedance Spectroscopy (IWIS), IEEE, 2025.'
date_created: 2025-12-03T16:06:09Z
date_updated: 2026-01-19T15:41:43Z
department:
- _id: '985'
doi: 10.1109/iwis63047.2024.10847115
extern: '1'
keyword:
- electrochemical impedance spectroscopy
- distorted cyclic voltammograms
- supercapacitors
- carbon
language:
- iso: eng
publication: 2024 International Workshop on Impedance Spectroscopy (IWIS)
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: Complementary Analysis of Cyclic Voltammograms and Impedance Spectra of Porous
Carbon Electrodes
type: conference
user_id: '116779'
year: '2025'
...
---
_id: '58853'
abstract:
- lang: eng
text: "Abstract\r\n While being a promising
approach for the treatment of infections caused by drug-resistant, pathogenic
bacteria, the clinical implementation of phage therapy still faces several challenges.
One of these challenges lies in the high strain-specificity of most bacteriophages,
which makes it necessary to screen large phage collections against the target
pathogens in order to identify suitable candidates for the formulations of personalized
therapeutic phage cocktails. In this work, we evaluate the potential of quartz
crystal microbalance with dissipation monitoring (QCM-D) to identify and detect
phage infection and subsequent lysis of bacteria immobilized on the surfaces of
the QCM-D sensors. Using lytic Escherichia coli phage
T7 as a model, we show that phage infection of E. coli
cells results in various unique alterations in the behaviors of the frequency
(Δf) and dissipation (ΔD)
signals, which are not observed during exposure of the E. coli
strain to non-infectious Bacillus subtilis phage phi29
at similar concentration. To aid future phage screening campaigns, we furthermore
identify a single measurement parameter, i.e., the spread between the different
overtones of ΔD, that can be used to detect phage-induced
lysis. For T7 infection of E. coli, this is achieved
within 4 h after inoculation, including immobilization and growth of the bacteria
on the sensor surface, as well as the completed phage propagation cycle. Given
the commercial availability of highly automated multichannel systems and the fact
that this approach does not require any sensor modifications, QCM-D has the potential
to become a valuable tool for screening medium-sized phage collections against
target pathogens.\r\n \r\n Graphical
Abstract\r\n "
author:
- first_name: Bhanu K.
full_name: Pothineni, Bhanu K.
last_name: Pothineni
- first_name: René
full_name: Probst, René
last_name: Probst
- first_name: Dorothee
full_name: Kiefer, Dorothee
last_name: Kiefer
- first_name: Verena
full_name: Dobretzberger, Verena
last_name: Dobretzberger
- first_name: Ivan
full_name: Barišić, Ivan
last_name: Barišić
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Pothineni BK, Probst R, Kiefer D, et al. Monitoring phage infection and lysis
of surface-immobilized bacteria by QCM-D. Analytical and Bioanalytical Chemistry.
Published online 2025. doi:10.1007/s00216-025-05803-5
apa: Pothineni, B. K., Probst, R., Kiefer, D., Dobretzberger, V., Barišić, I.,
Grundmeier, G., & Keller, A. (2025). Monitoring phage infection and lysis
of surface-immobilized bacteria by QCM-D. Analytical and Bioanalytical Chemistry.
https://doi.org/10.1007/s00216-025-05803-5
bibtex: '@article{Pothineni_Probst_Kiefer_Dobretzberger_Barišić_Grundmeier_Keller_2025,
title={Monitoring phage infection and lysis of surface-immobilized bacteria by
QCM-D}, DOI={10.1007/s00216-025-05803-5},
journal={Analytical and Bioanalytical Chemistry}, publisher={Springer Science
and Business Media LLC}, author={Pothineni, Bhanu K. and Probst, René and Kiefer,
Dorothee and Dobretzberger, Verena and Barišić, Ivan and Grundmeier, Guido and
Keller, Adrian}, year={2025} }'
chicago: Pothineni, Bhanu K., René Probst, Dorothee Kiefer, Verena Dobretzberger,
Ivan Barišić, Guido Grundmeier, and Adrian Keller. “Monitoring Phage Infection
and Lysis of Surface-Immobilized Bacteria by QCM-D.” Analytical and Bioanalytical
Chemistry, 2025. https://doi.org/10.1007/s00216-025-05803-5.
ieee: 'B. K. Pothineni et al., “Monitoring phage infection and lysis of surface-immobilized
bacteria by QCM-D,” Analytical and Bioanalytical Chemistry, 2025, doi:
10.1007/s00216-025-05803-5.'
mla: Pothineni, Bhanu K., et al. “Monitoring Phage Infection and Lysis of Surface-Immobilized
Bacteria by QCM-D.” Analytical and Bioanalytical Chemistry, Springer Science
and Business Media LLC, 2025, doi:10.1007/s00216-025-05803-5.
short: B.K. Pothineni, R. Probst, D. Kiefer, V. Dobretzberger, I. Barišić, G. Grundmeier,
A. Keller, Analytical and Bioanalytical Chemistry (2025).
date_created: 2025-02-26T09:23:19Z
date_updated: 2025-02-26T09:23:43Z
department:
- _id: '302'
doi: 10.1007/s00216-025-05803-5
language:
- iso: eng
publication: Analytical and Bioanalytical Chemistry
publication_identifier:
issn:
- 1618-2642
- 1618-2650
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Monitoring phage infection and lysis of surface-immobilized bacteria by QCM-D
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60507'
abstract:
- lang: eng
text: DNA origami nanostructures are powerful molecular tools for the controlled
arrangement of functional molecules and thus have important applications in biomedicine,
sensing, and materials science. The fabrication of DNA origami...
author:
- first_name: Emilia
full_name: Tomm, Emilia
id: '68157'
last_name: Tomm
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Tomm E, Grundmeier G, Keller A. Cost-efficient folding of functionalized DNA
origami nanostructures via staple recycling. Nanoscale. Published online
2025. doi:10.1039/d5nr01435b
apa: Tomm, E., Grundmeier, G., & Keller, A. (2025). Cost-efficient folding of
functionalized DNA origami nanostructures via staple recycling. Nanoscale.
https://doi.org/10.1039/d5nr01435b
bibtex: '@article{Tomm_Grundmeier_Keller_2025, title={Cost-efficient folding of
functionalized DNA origami nanostructures via staple recycling}, DOI={10.1039/d5nr01435b},
journal={Nanoscale}, publisher={Royal Society of Chemistry (RSC)}, author={Tomm,
Emilia and Grundmeier, Guido and Keller, Adrian}, year={2025} }'
chicago: Tomm, Emilia, Guido Grundmeier, and Adrian Keller. “Cost-Efficient Folding
of Functionalized DNA Origami Nanostructures via Staple Recycling.” Nanoscale,
2025. https://doi.org/10.1039/d5nr01435b.
ieee: 'E. Tomm, G. Grundmeier, and A. Keller, “Cost-efficient folding of functionalized
DNA origami nanostructures via staple recycling,” Nanoscale, 2025, doi:
10.1039/d5nr01435b.'
mla: Tomm, Emilia, et al. “Cost-Efficient Folding of Functionalized DNA Origami
Nanostructures via Staple Recycling.” Nanoscale, Royal Society of Chemistry
(RSC), 2025, doi:10.1039/d5nr01435b.
short: E. Tomm, G. Grundmeier, A. Keller, Nanoscale (2025).
date_created: 2025-07-03T11:26:30Z
date_updated: 2025-07-03T11:27:19Z
department:
- _id: '302'
doi: 10.1039/d5nr01435b
language:
- iso: eng
publication: Nanoscale
publication_identifier:
issn:
- 2040-3364
- 2040-3372
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Cost-efficient folding of functionalized DNA origami nanostructures via staple
recycling
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60606'
abstract:
- lang: eng
text: Streptavidin binding to DNA origami-supported high-density biotin
arrays is investigated for selected experimental parameters. While bidentate binding
and steric hindrance can be minimized, molecular crowding limits the binding yields
in 2D arrays.
author:
- first_name: Lukas
full_name: Rabbe, Lukas
last_name: Rabbe
- first_name: Emilia
full_name: Tomm, Emilia
id: '68157'
last_name: Tomm
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Rabbe L, Tomm E, Grundmeier G, Keller A. Toward high-density streptavidin arrays
on DNA origami nanostructures. RSC Advances. 2025;15(30):24536-24543. doi:10.1039/d5ra03393d
apa: Rabbe, L., Tomm, E., Grundmeier, G., & Keller, A. (2025). Toward high-density
streptavidin arrays on DNA origami nanostructures. RSC Advances, 15(30),
24536–24543. https://doi.org/10.1039/d5ra03393d
bibtex: '@article{Rabbe_Tomm_Grundmeier_Keller_2025, title={Toward high-density
streptavidin arrays on DNA origami nanostructures}, volume={15}, DOI={10.1039/d5ra03393d},
number={30}, journal={RSC Advances}, publisher={Royal Society of Chemistry (RSC)},
author={Rabbe, Lukas and Tomm, Emilia and Grundmeier, Guido and Keller, Adrian},
year={2025}, pages={24536–24543} }'
chicago: 'Rabbe, Lukas, Emilia Tomm, Guido Grundmeier, and Adrian Keller. “Toward
High-Density Streptavidin Arrays on DNA Origami Nanostructures.” RSC Advances
15, no. 30 (2025): 24536–43. https://doi.org/10.1039/d5ra03393d.'
ieee: 'L. Rabbe, E. Tomm, G. Grundmeier, and A. Keller, “Toward high-density streptavidin
arrays on DNA origami nanostructures,” RSC Advances, vol. 15, no. 30, pp.
24536–24543, 2025, doi: 10.1039/d5ra03393d.'
mla: Rabbe, Lukas, et al. “Toward High-Density Streptavidin Arrays on DNA Origami
Nanostructures.” RSC Advances, vol. 15, no. 30, Royal Society of Chemistry
(RSC), 2025, pp. 24536–43, doi:10.1039/d5ra03393d.
short: L. Rabbe, E. Tomm, G. Grundmeier, A. Keller, RSC Advances 15 (2025) 24536–24543.
date_created: 2025-07-15T06:06:48Z
date_updated: 2025-07-15T06:07:16Z
department:
- _id: '302'
doi: 10.1039/d5ra03393d
intvolume: ' 15'
issue: '30'
language:
- iso: eng
page: 24536-24543
publication: RSC Advances
publication_identifier:
issn:
- 2046-2069
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Toward high-density streptavidin arrays on DNA origami nanostructures
type: journal_article
user_id: '48864'
volume: 15
year: '2025'
...
---
_id: '60709'
abstract:
- lang: eng
text: Self-assembled DNA origami lattices have promising applications in
the fabrication of functional surfaces for sensing and plasmonics via molecular
lithography. While surface-assisted DNA origami lattice assembly at mica surfaces
is...
author:
- first_name: Adekunle
full_name: Omoboye, Adekunle
last_name: Omoboye
- first_name: Bhanu
full_name: Pothineni, Bhanu
last_name: Pothineni
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Zhe
full_name: She, Zhe
last_name: She
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Omoboye A, Pothineni B, Grundmeier G, She Z, Keller A. Surface potential-dependent
assembly of DNA origami lattices at SiO2 surfaces. RSC Applied Interfaces.
Published online 2025. doi:10.1039/d5lf00169b
apa: Omoboye, A., Pothineni, B., Grundmeier, G., She, Z., & Keller, A. (2025).
Surface potential-dependent assembly of DNA origami lattices at SiO2 surfaces.
RSC Applied Interfaces. https://doi.org/10.1039/d5lf00169b
bibtex: '@article{Omoboye_Pothineni_Grundmeier_She_Keller_2025, title={Surface potential-dependent
assembly of DNA origami lattices at SiO2 surfaces}, DOI={10.1039/d5lf00169b},
journal={RSC Applied Interfaces}, publisher={Royal Society of Chemistry (RSC)},
author={Omoboye, Adekunle and Pothineni, Bhanu and Grundmeier, Guido and She,
Zhe and Keller, Adrian}, year={2025} }'
chicago: Omoboye, Adekunle, Bhanu Pothineni, Guido Grundmeier, Zhe She, and Adrian
Keller. “Surface Potential-Dependent Assembly of DNA Origami Lattices at SiO2
Surfaces.” RSC Applied Interfaces, 2025. https://doi.org/10.1039/d5lf00169b.
ieee: 'A. Omoboye, B. Pothineni, G. Grundmeier, Z. She, and A. Keller, “Surface
potential-dependent assembly of DNA origami lattices at SiO2 surfaces,” RSC
Applied Interfaces, 2025, doi: 10.1039/d5lf00169b.'
mla: Omoboye, Adekunle, et al. “Surface Potential-Dependent Assembly of DNA Origami
Lattices at SiO2 Surfaces.” RSC Applied Interfaces, Royal Society of Chemistry
(RSC), 2025, doi:10.1039/d5lf00169b.
short: A. Omoboye, B. Pothineni, G. Grundmeier, Z. She, A. Keller, RSC Applied Interfaces
(2025).
date_created: 2025-07-22T07:17:24Z
date_updated: 2025-07-22T07:18:04Z
department:
- _id: '302'
doi: 10.1039/d5lf00169b
language:
- iso: eng
publication: RSC Applied Interfaces
publication_identifier:
issn:
- 2755-3701
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Surface potential-dependent assembly of DNA origami lattices at SiO2 surfaces
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '60973'
abstract:
- lang: eng
text: The specific binding of DNA origami nanostructures (DONs) to bacteria
is an important prerequisite for their application in pathogen targeting and antimicrobial
drug delivery. So far, targeting bacteria with DONs has been achieved exclusively
via aptamers, which suffer from drawbacks such as sensitivity toward environmental
conditions and reduced binding after immobilization or conjugation. Here, an alternative
approach is presented based on the modification of DONs with the cell wall‐binding
glycopeptide antibiotic vancomycin. Using strain‐promoted azide‐alkyne cycloaddition,
azide‐modified vancomycin is conjugated to selected staple strands and subsequently
incorporated into 2D DON triangles. The resulting constructs show specific binding
to the Gram‐positive species Bacillus subtilis (B.
subtilis) and Staphylococcus capitis
(S. capitis), and remarkably, to Gram‐negative Escherichia
coli (E. coli), but no antimicrobial
activity at vancomycin concentrations up to at least 2.91 μM. For B.
subtilis and E. coli, DONs with vancomycin
modifications on both sides exhibit better binding than DONs modified on only
one side. However, both variants bind equally well to S. capitis.
These results demonstrate the great potential of small molecule drug compounds
for the robust, broad‐spectrum targeting of bacteria with DONs. Targeting a ubiquitous
cell wall component of most pathogenic bacteria, vancomycin‐modified DONs have
many potential applications in the prevention and treatment of nosocomial infections.
article_number: '2500246'
author:
- first_name: Özge
full_name: Coşkuner Leineweber, Özge
last_name: Coşkuner Leineweber
- first_name: Bhanu K.
full_name: Pothineni, Bhanu K.
last_name: Pothineni
- first_name: Nils
full_name: Schumann, Nils
last_name: Schumann
- first_name: Ulrike
full_name: Hofmann, Ulrike
last_name: Hofmann
- first_name: Christin
full_name: Möser, Christin
last_name: Möser
- first_name: David M.
full_name: Smith, David M.
last_name: Smith
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Yixin
full_name: Zhang, Yixin
last_name: Zhang
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Coşkuner Leineweber Ö, Pothineni BK, Schumann N, et al. Vancomycin‐Modified
DNA Origami Nanostructures for Targeting Bacterial Pathogens. Small Structures.
Published online 2025. doi:10.1002/sstr.202500246
apa: Coşkuner Leineweber, Ö., Pothineni, B. K., Schumann, N., Hofmann, U., Möser,
C., Smith, D. M., Grundmeier, G., Zhang, Y., & Keller, A. (2025). Vancomycin‐Modified
DNA Origami Nanostructures for Targeting Bacterial Pathogens. Small Structures,
Article 2500246. https://doi.org/10.1002/sstr.202500246
bibtex: '@article{Coşkuner Leineweber_Pothineni_Schumann_Hofmann_Möser_Smith_Grundmeier_Zhang_Keller_2025,
title={Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial
Pathogens}, DOI={10.1002/sstr.202500246},
number={2500246}, journal={Small Structures}, publisher={Wiley}, author={Coşkuner
Leineweber, Özge and Pothineni, Bhanu K. and Schumann, Nils and Hofmann, Ulrike
and Möser, Christin and Smith, David M. and Grundmeier, Guido and Zhang, Yixin
and Keller, Adrian}, year={2025} }'
chicago: Coşkuner Leineweber, Özge, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann,
Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, and Adrian Keller.
“Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens.”
Small Structures, 2025. https://doi.org/10.1002/sstr.202500246.
ieee: 'Ö. Coşkuner Leineweber et al., “Vancomycin‐Modified DNA Origami Nanostructures
for Targeting Bacterial Pathogens,” Small Structures, Art. no. 2500246,
2025, doi: 10.1002/sstr.202500246.'
mla: Coşkuner Leineweber, Özge, et al. “Vancomycin‐Modified DNA Origami Nanostructures
for Targeting Bacterial Pathogens.” Small Structures, 2500246, Wiley, 2025,
doi:10.1002/sstr.202500246.
short: Ö. Coşkuner Leineweber, B.K. Pothineni, N. Schumann, U. Hofmann, C. Möser,
D.M. Smith, G. Grundmeier, Y. Zhang, A. Keller, Small Structures (2025).
date_created: 2025-08-22T06:02:45Z
date_updated: 2025-08-22T06:04:06Z
department:
- _id: '302'
doi: 10.1002/sstr.202500246
language:
- iso: eng
publication: Small Structures
publication_identifier:
issn:
- 2688-4062
- 2688-4062
publication_status: published
publisher: Wiley
status: public
title: Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens
type: journal_article
user_id: '48864'
year: '2025'
...
---
_id: '61821'
abstract:
- lang: eng
text: AbstractControlling the surface orientation
of DNA origami nanostructures (DON) is crucial for applications in nanotechnology
and materials science. While previous work utilized various DON modifications,
simple methods for controlling their landing orientation remain scarce. Here,
we demonstrate a straightforward approach to control the adsorption orientation
of chiral double‐L (CDL) DON on mica by tuning magnesium ion (Mg2⁺)
concentration and exploiting global shape distortions. Using atomic force microscopy
(AFM), we analyzed the resulting distribution of the mirror‐image orientations,
referred to as S and Z orientations, at both buffer/mica and air/mica interfaces
and identified conditions resulting in homogenous CDL orientation of 100% S. These
results demonstrate how DON conformation and ionic environments influence DON
orientation, offering insights for precise nanostructure deposition.
article_number: e202507613
author:
- first_name: Gangamallaiah
full_name: Velpula, Gangamallaiah
last_name: Velpula
- first_name: Emilia
full_name: Tomm, Emilia
last_name: Tomm
- first_name: Boxuan
full_name: Shen, Boxuan
last_name: Shen
- first_name: Kunal S.
full_name: Mali, Kunal S.
last_name: Mali
- first_name: Adrian Clemens
full_name: Keller, Adrian Clemens
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Steven
full_name: De Feyter, Steven
last_name: De Feyter
citation:
ama: Velpula G, Tomm E, Shen B, Mali KS, Keller AC, De Feyter S. Breaking of the
Up‐Down Symmetry of DNA Origami on a Solid Substrate. Angewandte Chemie International
Edition. Published online 2025. doi:10.1002/anie.202507613
apa: Velpula, G., Tomm, E., Shen, B., Mali, K. S., Keller, A. C., & De Feyter,
S. (2025). Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate.
Angewandte Chemie International Edition, Article e202507613. https://doi.org/10.1002/anie.202507613
bibtex: '@article{Velpula_Tomm_Shen_Mali_Keller_De Feyter_2025, title={Breaking
of the Up‐Down Symmetry of DNA Origami on a Solid Substrate}, DOI={10.1002/anie.202507613},
number={e202507613}, journal={Angewandte Chemie International Edition}, publisher={Wiley},
author={Velpula, Gangamallaiah and Tomm, Emilia and Shen, Boxuan and Mali, Kunal
S. and Keller, Adrian Clemens and De Feyter, Steven}, year={2025} }'
chicago: Velpula, Gangamallaiah, Emilia Tomm, Boxuan Shen, Kunal S. Mali, Adrian
Clemens Keller, and Steven De Feyter. “Breaking of the Up‐Down Symmetry of DNA
Origami on a Solid Substrate.” Angewandte Chemie International Edition,
2025. https://doi.org/10.1002/anie.202507613.
ieee: 'G. Velpula, E. Tomm, B. Shen, K. S. Mali, A. C. Keller, and S. De Feyter,
“Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate,” Angewandte
Chemie International Edition, Art. no. e202507613, 2025, doi: 10.1002/anie.202507613.'
mla: Velpula, Gangamallaiah, et al. “Breaking of the Up‐Down Symmetry of DNA Origami
on a Solid Substrate.” Angewandte Chemie International Edition, e202507613,
Wiley, 2025, doi:10.1002/anie.202507613.
short: G. Velpula, E. Tomm, B. Shen, K.S. Mali, A.C. Keller, S. De Feyter, Angewandte
Chemie International Edition (2025).
date_created: 2025-10-13T13:53:22Z
date_updated: 2025-10-13T13:55:05Z
department:
- _id: '302'
doi: 10.1002/anie.202507613
language:
- iso: eng
publication: Angewandte Chemie International Edition
publication_identifier:
issn:
- 1433-7851
- 1521-3773
publication_status: published
publisher: Wiley
status: public
title: Breaking of the Up‐Down Symmetry of DNA Origami on a Solid Substrate
type: journal_article
user_id: '48864'
year: '2025'
...