@article{63881,
abstract = {{Abstract
The relationship between leptin levels and psychiatric disorders has been studied more extensively in adults than in children and adolescents. However, the results are conflicting. We investigated serum leptin levels in children and adolescents (11 to 18.9 years) with psychiatric disorders (
n
= 363). Absolute and relative (body-mass-index (BMI)-, sex- and pubertal-stage-adjusted z-scores using reference values of healthy children and adolescents) leptin levels of different patient groups according to diagnosis were compared. The association between leptin levels and depression (Beck Depression Inventory-II) and anxiety (Child Behavior Checklist and Youth Self Report) was examined using regression analysis. Leptin z-scores were higher in patients with psychiatric disorders than in healthy controls (median 1.50,
p
< .001). While global tests suggested differences in leptin z-scores between patients with different psychiatric disorders, these differences could not be attributed to diagnosis groups in post-hoc pairwise comparisons. Absolute leptin levels differed between psychiatric disorders (
p
< .001). Patients with anorexia nervosa (AN) had the lowest levels, and patients with mood disorders had higher leptin levels than patients with mental disorders other than mood disorders, anxiety or AN. Neither absolute nor relative leptin levels were related to depressive or anxiety symptoms in regression models adjusted for sex and BMI. Significantly elevated BMI-, sex- and puberty-stage-adjusted leptin levels were observed in children and adolescents with psychiatric disorders compared to a reference sample. Further controlled studies are needed to confirm and explain this finding. No relationship was found between absolute or relative leptin levels and symptoms of depression or anxiety.
}},
author = {{Albers, Nicola and Antel, Jochen and Föcker, Manuel and Libuda, Lars and Bühlmeier, Judith and Hirtz, Raphael and Seitz, Jochen and Hinney, Anke and Hebebrand, Johannes and Peters, Triinu}},
issn = {{1018-8827}},
journal = {{European Child & Adolescent Psychiatry}},
publisher = {{Springer Science and Business Media LLC}},
title = {{{Children and adolescents with psychiatric disorders have high relative leptin levels upon adjustment for sex, BMI, and pubertal status}}},
doi = {{10.1007/s00787-025-02921-4}},
year = {{2026}},
}
@article{63880,
author = {{Knoll-Pientka, Nadja and Schils, Dorina and Mantwill, Katrin and Dinse, Hannah and Skoda, Eva-Maria and Bäuerle, Alexander and Teufel, Martin and Libuda, Lars}},
issn = {{2055-0928}},
journal = {{BMC Nutrition}},
publisher = {{Springer Science and Business Media LLC}},
title = {{{Adherence to dietary recommendations according to the General Dietary Behavior Inventory (GDBI) and its association with bioelectrical impedance analysis (BIA) parameters among young, healthy and normal weight women}}},
doi = {{10.1186/s40795-026-01260-0}},
year = {{2026}},
}
@article{67282,
abstract = {{Abstract
Diet impacts cardiovascular disease risk, but the association across diabetes subtypes is unclear. We thus aimed to assess the association between dietary factors and estimated 10-year cardiovascular disease risk across diabetes subtypes in the German Diabetes Study (GDS). Participants with recent-onset diabetes and from the 5-year follow-up examination were combined (n=635, mean age 47.5±12.9 years, 60% male) and classified into diabetes subtypes. Subtypes with prevalence >10% were included in cross-sectional analyses: severe autoimmune diabetes (39%), mild obesity-related diabetes (31%), and mild age-related diabetes (30%). Carbohydrate quality parameters and adherence to dietary patterns were assessed from food frequency questionnaires. Differences in associations between these dietary factors and 10-year cardiovascular risk estimated by SCORE2-Diabetes across subtypes were examined using multivariable-adjusted linear regression models including an interaction term. In people with severe autoimmune diabetes, the overall and the healthful plant-based diet index were associated with lower estimated 10-year cardiovascular risk (ß [95% CI] -6.8 [-12.1; -1.2] and -8.8% [-14.0; -3.2] per 1-standard deviation increases, respectively), while these associations were not evident among the remaining two subtypes (p-value for interaction between subtypes <0.05). Our findings suggest subtype-specific associations of plant-based dietary patterns with estimated cardiovascular risk, warranting further research from longitudinal and intervention studies.
Trial registration:
Clinicaltrials.gov: NCT01055093
}},
author = {{Weber, Katharina S. and Schlesinger, Sabrina and Lang, Alexander and Goletzke, Janina and Övermöhle, Cara and Strathmann, Eike A. and Straßburger, Klaus and Singh, Nitika and Zaharia, Oana-Patricia and Trenkamp, Sandra and Wagner, Robert and Lieb, Wolfgang and Buyken, Anette and Roden, Michael and Herder, Christian and Al-Hasani, H. and Belgardt, B. and Bönhof, G.J. and Geerling, G. and Icks, A. and Jandeleit-Dahm, K. and Kuß, O. and Lammert, E. and Schlesinger, S. and Schrauwen-Hinderling, V. and Szendroedi, J. and Trenkamp, Sandra}},
issn = {{2045-2322}},
journal = {{Scientific Reports}},
number = {{1}},
publisher = {{Springer Science and Business Media LLC}},
title = {{{Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes}}},
doi = {{10.1038/s41598-026-57026-y}},
volume = {{16}},
year = {{2026}},
}
@article{67283,
author = {{Della Corte, Karen A. and Buyken, Anette and La Vecchia, Carlo and Vanginkel, Marie-Ann and Salas-Salvadó, Jordi and Riccardi, Gabriele and Trichopoulou, Antonia and Slavin, Joanne and Ceriello, Antonio and Bulló, Mònica and Risérus, Ulf and Ellis, Peter R. and Astrup, Arne and Barclay, Alan and Sievenpiper, John L. and Chiavaroli, Laura and Liu, Simin and Kendall, Cyril W.C. and Livesey, Geoffrey and Jenkins, David J.A. and Brand-Miller, Jennie C. and Willett, Walter C. and Augustin, Livia S.A.}},
issn = {{2161-8313}},
journal = {{Advances in Nutrition}},
publisher = {{Elsevier BV}},
title = {{{Toward International Dietary Guidance: A Food Guide Pyramid for Human and Planetary Health}}},
doi = {{10.1016/j.advnut.2026.100738}},
year = {{2026}},
}
@article{60179,
author = {{Weber, KS and Schlesinger, S and Goletzke, J and Straßburger, K and Zaharia, OP and Trenkamp, S and Wagner, R and Lieb, W and Buyken, Anette and Roden, M and Herder, C and group, GDS}},
issn = {{1475-2840}},
journal = {{Cardiovasc Diabetol}},
number = {{1}},
pages = {{53}},
title = {{{Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes.}}},
volume = {{24}},
year = {{2025}},
}
@article{60180,
author = {{Kranz, RM and Kettler, C and Anand, C and Koeder, C and Husain, S and Schoch, N and Buyken, Anette and Englert, H}},
issn = {{0260-1060}},
journal = {{Nutr Health}},
number = {{1}},
pages = {{175--186}},
title = {{{Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2).}}},
volume = {{31}},
year = {{2025}},
}
@article{63882,
author = {{Dinkelbach, Lars and Wudy, Stefan A. and Hartmann, Michaela F. and Libuda, Lars and Föcker, Manuel and Hebebrand, Johannes and Hinney, Anke and Nöthlings, Ute and Alexy, Ute and Grasemann, Corinna and Hirtz, Raphael}},
issn = {{0165-0327}},
journal = {{Journal of Affective Disorders}},
publisher = {{Elsevier BV}},
title = {{{Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depressive symptoms}}},
doi = {{10.1016/j.jad.2025.120867}},
volume = {{399}},
year = {{2025}},
}
@article{62900,
author = {{Hjorth, Therese and Schadow, Alena Marie and Revheim, Ingrid and Spielau, Ulrike and Meyer, Klara and Rieder, Anne and Varela, Paula and Ballance, Simon and Koerner, Antje and Landberg, Rikard and Buyken, Anette and Dierkes, Jutta and Rosendahl-Riise, Hanne}},
issn = {{0002-9165}},
journal = {{The American Journal of Clinical Nutrition}},
number = {{3}},
pages = {{724--732}},
publisher = {{Elsevier BV}},
title = {{{Effectiveness of regular oat β-glucan–enriched bread compared with whole-grain wheat bread on long-term glycemic control in adults at risk of type 2 diabetes: a randomized controlled trial}}},
doi = {{10.1016/j.ajcnut.2025.06.018}},
volume = {{122}},
year = {{2025}},
}
@article{59229,
abstract = {{Die Nahrungszubereitung als zentraler Bestandteil eines haushaltsbezogenen Unterrichts dient der Anbahnung von Kompetenzen für die Zubereitung von Speisen und die Gestaltung von Mahlzeiten unter Berücksichtigung von Gesundheit und Nachhaltigkeit. Ebenso bedeutsam, jedoch häufig vernachlässigt, ist die Berücksichtigung unterschiedlicher Esskulturen, lebensweltlicher Erfahrungen und sozioökonomischer Hintergründe der Lernenden.}},
author = {{Schlegel-Matthies, Kirsten}},
issn = {{2193-8806}},
journal = {{HiBiFo – Haushalt in Bildung & Forschung}},
number = {{1}},
pages = {{49--63}},
publisher = {{Verlag Barbara Budrich GmbH}},
title = {{{Essen in der Vielfalt – Esskultur und Nahrungszubereitung}}},
doi = {{10.3224/hibifo.v14i1.05}},
volume = {{14}},
year = {{2025}},
}
@article{60186,
author = {{Lang, A and Schaefer, E and Kupriyanova, Y and Goletzke, J and Weber, KS and Buyken, Anette and Kahl, S and Zaharia, OP and Herder, C and Schrauwen-Hinderling, VB and Kuss, O and Wagner, R and Roden, M and Schlesinger, S and Diabetes Study Group, German}},
issn = {{1475-2891}},
journal = {{Nutr J}},
number = {{1}},
pages = {{74}},
title = {{{Cross-sectional association between the isocaloric replacement of carbohydrates with protein and fat in relation to fat compartments distribution and hepatic lipid content in recent-onset type 1 and type 2 diabetes.}}},
volume = {{24}},
year = {{2025}},
}
@article{60182,
author = {{Perrar, I and Hohoff, E and Lesani, A and Schmitting, S and Libuda, Lars and Krüger, Bettina and Stutz, Bianca and Nöthlings, U and Buyken, Anette and Alexy, U and Jankovic, N}},
issn = {{1436-6207}},
journal = {{Eur J Nutr}},
number = {{4}},
pages = {{165}},
title = {{{Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study.}}},
volume = {{64}},
year = {{2025}},
}
@article{60184,
author = {{Della Corte, KA and Bosler, T and McClure, C and Buyken, Anette and LeCheminant, JD and Schwingshackl, L and Della Corte, D}},
issn = {{2161-8313}},
journal = {{Adv Nutr}},
number = {{5}},
pages = {{100413}},
title = {{{Dietary Sugar Intake and Incident Type 2 Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.}}},
volume = {{16}},
year = {{2025}},
}
@article{60187,
author = {{Revheim, I and Sabir, Z and Dierkes, J and Buyken, Anette and Landberg, R and Alten, I and Spielau, U and Rosendahl-Riise, H}},
issn = {{1436-6207}},
journal = {{Eur J Nutr}},
number = {{5}},
pages = {{197}},
title = {{{Bread, wholegrain consumption and weight change from middle to late adulthood: a prospective cohort study. }}},
volume = {{64}},
year = {{2025}},
}
@article{60181,
author = {{Dannheim, I and Ludwig-Walz, H and Kirsch, H and Bujard, M and Buyken, Anette and Richardson, KM and Kroke, A}},
issn = {{0355-3140}},
journal = {{Scand J Work Environ Health}},
pages = {{4219}},
title = {{{Effectiveness of leader-targeted stress management interventions: A systematic review and meta-analysis.}}},
year = {{2025}},
}
@misc{60336,
author = {{Schlegel-Matthies, Kirsten}},
booktitle = {{Haushalt in Bildung und Forschung}},
issn = {{2196-1662}},
number = {{1}},
pages = {{49--63}},
title = {{{Essen in der Vielfalt – Esskultur und Nahrungszubereitung}}},
volume = {{14}},
year = {{2025}},
}
@article{60471,
author = {{Knoll-Pientka, N and Schils, D and Pasternak, K and Czarnetzky, S and Jansen, C and Gradl-Dietsch, G and Seitz, J and Skoda, EM and Libuda, Lars and Schweda, A and Teufel, M}},
issn = {{2050-2974}},
journal = {{J Eat Disord}},
number = {{1}},
pages = {{87}},
title = {{{Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women.}}},
volume = {{13}},
year = {{2025}},
}
@article{60873,
abstract = {{Abstract
Variations in circadian rhythm-related genes influence the individual chronotype. Here, we hypothesize that the peak of clock gene expression at 7 a.m. differs between young adults with a late chronotype and young adults with an early chronotype. Participants of the Chronotype and Nutrition nutritional trial (ChroNu study) were selected for their chronotype assessed by the Munich Chronotype questionnaire (MCTQ) and actigraphy. Total RNA was isolated from CD14+ monocytes of participants at 7 a.m. on the run-in day. Expression levels of seven clock genes (PER1, PER2, PER3, NR1D1, NR1D2, CRY1 and CRISPLD2) of individuals with early (n = 11) or late chronotypes (n = 19) were analysed by reverse transcription quantitative polymerase chain reaction. Difference in expression levels was tested by Mann Whitney-U test. The relative expression levels of the selected genes were not significantly different between individuals with early and late chronotypes (all p > 0.07). Contrary to expectation, clock gene expression levels at 7 a.m. was similar in individuals with early and late chronotypes. Further studies on larger sample sizes with multiple sampling time points should elucidate whether gene expression is altered at other day times underscoring the biological difference between individuals with early or late chronotypes.}},
author = {{Krueger, Bettina and Rajcsanyi, Luisa Sophie and Hundertmark, Katharina and Stutz, Bianca and Hinney, Anke and Buyken, Anette E.}},
issn = {{2045-2322}},
journal = {{Scientific Reports}},
number = {{1}},
publisher = {{Springer Science and Business Media LLC}},
title = {{{Morning clock gene expression in young adults of early and late chronotypes}}},
doi = {{10.1038/s41598-025-12423-7}},
volume = {{15}},
year = {{2025}},
}
@article{50740,
author = {{Weber, Katharina S. and Schlesinger, Sabrina and Lang, Alexander and Straßburger, Klaus and Maalmi, Haifa and Zhu, Anna and Zaharia, Oana-Patricia and Strom, Alexander and Bönhof, Gidon J. and Goletzke, Janina and Trenkamp, Sandra and Wagner, Robert and Buyken, Anette and Lieb, Wolfgang and Roden, Michael and Herder, Christian and Roden, M. and Al-Hasani, H. and Belgardt, B. and Lammert, E. and Bönhof, G. and Geerling, G. and Herder, C. and Icks, A. and Jandeleit-Dahm, K. and Kotzka, J. and Kuß, O. and Rathmann, W. and Schlesinger, S. and Schrauwen-Hinderling, V. and Szendroedi, J. and Trenkamp, S. and Wagner, R.}},
issn = {{0939-4753}},
journal = {{Nutrition, Metabolism and Cardiovascular Diseases}},
keywords = {{Cardiology and Cardiovascular Medicine, Nutrition and Dietetics, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous)}},
publisher = {{Elsevier BV}},
title = {{{Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes}}},
doi = {{10.1016/j.numecd.2023.12.026}},
year = {{2024}},
}
@article{52712,
author = {{Buyken, Anette and Libuda, Lars}},
journal = {{DGEwissen}},
title = {{{Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft}}},
year = {{2024}},
}
@article{52713,
abstract = {{ABSTRACT
OBJECTIVE:
The aim of this analysis was to investigate whether habitual intake of total dairy (TD) or different dairy types (liquid, solid, fermented, not-fermented, low-fat, high-fat, low-sugar and high-sugar dairy) during adolescence is associated with biomarkers of low-grade inflammation as well as risk factors of type 2 diabetes in young adulthood.
DESIGN:
Multivariable linear regression analyses were used to investigate prospective associations between estimated TD intake as well as intake of different types of dairy and a pro-inflammatory score, based on hsCRP, IL-6, IL-18, leptin and adiponectin, and insulin resistance assessed as HOMA2-IR in an open cohort study.
SETTING:
Dortmund, Germany
PARTICIPANTS:
Data from participants (n=375) of the DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study were included, for whom at least two 3-day weighed dietary records during adolescence (median age: 11 years) and one blood sample in young adulthood (>18 years) were available.
RESULTS:
There was no statistically significant association between TD intake or intake of any dairy type and the pro-inflammatory score (all p>0.05). TD intake as well as each dairy type intake and insulin resistance also showed no association (all p>0.05).
CONCLUSIONS:
The habitual intake of dairy or individual types of dairy during adolescence does not seem to have a major impact on low-grade systemic inflammation and insulin resistance in the long term. There was no indication regarding a restriction of dairy intake for healthy children and adolescents in terms of diabetes risk reduction.
}},
author = {{Hohoff, E and Jankovic, N and Perrar, I and Schnermann, ME and Herder, C and Nöthlings, U and Libuda, Lars and Alexy, U}},
issn = {{1368-9800}},
journal = {{Public Health Nutrition}},
keywords = {{Public Health, Environmental and Occupational Health, Nutrition and Dietetics, Medicine (miscellaneous)}},
pages = {{1--26}},
publisher = {{Cambridge University Press (CUP)}},
title = {{{The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study}}},
doi = {{10.1017/s1368980024000624}},
year = {{2024}},
}