@article{26914,
  author       = {{Joslowski, Gesa and Halim, Jocelyn and Goletzke, Janina and Gow, Megan and Ho, Mandy and Louie, Jimmy C.-Y. and Buyken, Anette and Cowell, Chris T. and Garnett, Sarah P.}},
  issn         = {{0261-5614}},
  journal      = {{Clinical Nutrition}},
  pages        = {{89--94}},
  title        = {{{Dietary glycemic load, insulin load, and weight loss in obese, insulin resistant adolescents: RESIST study}}},
  doi          = {{10.1016/j.clnu.2014.01.015}},
  year         = {{2014}},
}

@article{26915,
  author       = {{Buyken, Anette and Goletzke, Janina and Joslowski, Gesa and Felbick, Anna and Cheng, Guo and Herder, Christian and Brand-Miller, Jennie C}},
  issn         = {{0002-9165}},
  journal      = {{The American Journal of Clinical Nutrition}},
  pages        = {{813--833}},
  title        = {{{Association between carbohydrate quality and inflammatory markers: systematic review of observational and interventional studies}}},
  doi          = {{10.3945/ajcn.113.074252}},
  year         = {{2014}},
}

@article{26916,
  author       = {{Cheng, G and Bolzenius, K and Joslowski, G and Günther, A L B and Kroke, A and Heinrich, J and Buyken, Anette}},
  issn         = {{0954-3007}},
  journal      = {{European Journal of Clinical Nutrition}},
  pages        = {{262--268}},
  title        = {{{Velocities of weight, height and fat mass gain during potentially critical periods of growth are decisive for adult body composition}}},
  doi          = {{10.1038/ejcn.2014.131}},
  year         = {{2014}},
}

@article{26917,
  author       = {{Goletzke, Janina and Buyken, Anette and Joslowski, Gesa and Bolzenius, Katja and Remer, Thomas and Carstensen, Maren and Egert, Sarah and Nöthlings, Ute and Rathmann, Wolfgang and Roden, Michael and Herder, Christian}},
  issn         = {{0022-3166}},
  journal      = {{The Journal of Nutrition}},
  pages        = {{1586--1593}},
  title        = {{{Increased Intake of Carbohydrates from Sources with a Higher Glycemic Index and Lower Consumption of Whole Grains during Puberty Are Prospectively Associated with Higher IL-6 Concentrations in Younger Adulthood among Healthy Individuals}}},
  doi          = {{10.3945/jn.114.193391}},
  year         = {{2014}},
}

@article{27041,
  author       = {{Stimming, Madlen and Mesch, Christina M. and Kersting, Mathilde and Libuda, Lars}},
  issn         = {{1436-6207}},
  journal      = {{European Journal of Nutrition}},
  pages        = {{1069--1080}},
  title        = {{{Fish and rapeseed oil consumption in infants and mothers: dietary habits and determinants in a nationwide sample in Germany}}},
  doi          = {{10.1007/s00394-014-0784-y}},
  year         = {{2014}},
}

@article{27042,
  author       = {{Stimming, Madlen and Mesch, Christina M. and Kersting, Mathilde and Kalhoff, Hermann and Demmelmair, Hans and Koletzko, Berthold and Schmidt, Anne and Böhm, Volker and Libuda, Lars}},
  issn         = {{0021-8561}},
  journal      = {{Journal of Agricultural and Food Chemistry}},
  pages        = {{10153--10161}},
  title        = {{{Vitamin E Content and Estimated Need in German Infant and Follow-On Formulas With and Without Long-Chain Polyunsaturated Fatty Acids (LC-PUFA) Enrichment}}},
  doi          = {{10.1021/jf502469b}},
  year         = {{2014}},
}

@article{27044,
  author       = {{Vyncke, Krishna and Huybrechts, Inge and Van Winckel, Myriam and Cuenca Garcia, Magdalena and Labayen, Idoia and Gottrand, Frederic and Widhalm, Kurt and Leclercq, Catherine and Libuda, Lars and Manios, Yannis and Sjostrom, Michael and Molnar, Denes and Moreno, Luis A. and Gonzalez-Gross, Marcela and Spinneker, André and Perez de Heredia, Fatima and Plada, Maria and De Henauw, Stefaan}},
  issn         = {{0024-4201}},
  journal      = {{Lipids}},
  pages        = {{881--893}},
  title        = {{{Dietary Lipid Intake only Partially Influences Variance in Serum Phospholipid Fatty Acid Composition in Adolescents: Impact of Other Dietary Factors}}},
  doi          = {{10.1007/s11745-014-3935-2}},
  year         = {{2014}},
}

@article{27059,
  abstract     = {{<jats:p>The present study aimed to investigate the relationships between macronutrient intake and serum lipid profile in adolescents from eight European cities participating in the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) cross-sectional study (2006–7), and to assess the role of body fat-related variables in these associations. Weight, height, waist circumference, skinfold thicknesses, total cholesterol, HDL-cholesterol (HDL-C), LDL-cholesterol, TAG, apoB and apoA1 were measured in 454 adolescents (44 % boys) aged 12·5–17·5 years. Macronutrient intake (g/4180 kJ per d (1000 kcal per d)) was assessed using two non-consecutive 24 h dietary recalls. Associations were evaluated by multi-level analysis and adjusted for sex, age, maternal education, centre, sum of four skinfolds, moderate-to-vigorous physical activity, sedentary behaviours and diet quality index for adolescents. Carbohydrate intake was inversely associated with HDL-C (β = − 0·189, <jats:italic>P</jats:italic>&lt; 0·001). An inverse association was found between fat intake and TAG (β = − 0·319, <jats:italic>P</jats:italic>&lt; 0·001). Associations between macronutrient intake and serum lipids varied according to adiposity levels, i.e. an inverse association between carbohydrate intake and HDL-C was only observed in those adolescents with a higher waist:height ratio. As serum lipids and excess body fat are the major markers of CVD, these findings should be considered when developing strategies to prevent the risk of CVD among adolescents.</jats:p>}},
  author       = {{Bel-Serrat, Silvia and Mouratidou, Theodora and Huybrechts, Inge and Labayen, Idoia and Cuenca-García, Magdalena and Palacios, Gonzalo and Breidenassel, Christina and Molnár, Dénes and Roccaldo, Romana and Widhalm, Kurt and Gottrand, Frederic and Kafatos, Anthony and Manios, Yannis and Vyncke, Krishna and Sjöström, Michael and Libuda, Lars and Gómez-Martínez, Sonia and Moreno, Luis A.}},
  issn         = {{0007-1145}},
  journal      = {{British Journal of Nutrition}},
  pages        = {{2049--2059}},
  title        = {{{Associations between macronutrient intake and serum lipid profile depend on body fat in European adolescents: the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study}}},
  doi          = {{10.1017/s0007114514003183}},
  year         = {{2014}},
}

@article{27060,
  author       = {{Mesch, Christina M. and Stimming, Madlen and Foterek, Kristina and Hilbig, Annett and Alexy, Ute and Kersting, Mathilde and Libuda, Lars}},
  issn         = {{0195-6663}},
  journal      = {{Appetite}},
  pages        = {{113--119}},
  title        = {{{Food variety in commercial and homemade complementary meals for infants in Germany. Market survey and dietary practice}}},
  doi          = {{10.1016/j.appet.2014.01.074}},
  year         = {{2014}},
}

@article{27768,
  author       = {{Riedel, Christina and von Kries, Rüdiger and Buyken, Anette and Diethelm, Katharina and Keil, Thomas and Grabenhenrich, Linus and Müller, Manfred J. and Plachta-Danielzik, Sandra}},
  issn         = {{1932-6203}},
  journal      = {{PLoS ONE}},
  title        = {{{Overweight in Adolescence Can Be Predicted at Age 6 Years: A CART Analysis in German Cohorts}}},
  doi          = {{10.1371/journal.pone.0093581}},
  year         = {{2014}},
}

@article{36062,
  author       = {{Schlegel-Matthies, Kirsten and Methfessel, Barbara}},
  journal      = {{Hauswirtschaft und Wissenschaft}},
  number       = {{1}},
  pages        = {{27--38}},
  title        = {{{ Alltagskultur: viel beschworen, wenig wissenschaftlich durchdrungen?!}}},
  volume       = {{52}},
  year         = {{2014}},
}

@article{54943,
  abstract     = {{Proteolytic activation is a unique feature of the epithelial sodium channel (ENaC). However, the underlying molecular mechanisms and the physiologically relevant proteases remain to be identified. The serine protease trypsin I can activate ENaC in vitro but is unlikely to be the physiologically relevant activating protease in ENaC-expressing tissues in vivo. Herein, we investigated whether human trypsin IV, a form of trypsin that is co-expressed in several extrapancreatic epithelial cells with ENaC, can activate human ENaC. In Xenopus laevis oocytes, we monitored proteolytic activation of ENaC currents and the appearance of $\gamma$ENaC cleavage products at the cell surface. We demonstrated that trypsin IV and trypsin I can stimulate ENaC heterologously expressed in oocytes. ENaC cleavage and activation by trypsin IV but not by trypsin I required a critical cleavage site (Lys-189) in the extracellular domain of the $\gamma$-subunit. In contrast, channel activation by trypsin I was prevented by mutating three putative cleavage sites (Lys-168, Lys-170, and Arg-172) in addition to mutating previously described prostasin (RKRK(178)), plasmin (Lys-189), and neutrophil elastase (Val-182 and Val-193) sites. Moreover, we found that trypsin IV is expressed in human renal epithelial cells and can increase ENaC-mediated sodium transport in cultured human airway epithelial cells. Thus, trypsin IV may regulate ENaC function in epithelial tissues. Our results show, for the first time, that trypsin IV can stimulate ENaC and that trypsin IV and trypsin I activate ENaC by cleavage at distinct sites. The presence of distinct cleavage sites may be important for ENaC regulation by tissue-specific proteases.}},
  author       = {{Haerteis, Silke and Krappitz, Annabel and Krappitz, Matteus and Murphy, Jane E. and Bertog, Marko and Krueger, Bettina and Nacken, Regina and Chung, Hyunjae and Hollenberg, Morley D. and Knecht, Wolfgang and Bunnett, Nigel W. and Korbmacher, Christoph}},
  journal      = {{Journal of Biological Chemistry}},
  number       = {{27}},
  pages        = {{19067–19078}},
  publisher    = {{Elsevier}},
  title        = {{{Proteolytic Activation of the Human Epithelial Sodium Channel by Trypsin IV and Trypsin I Involves Distinct Cleavage Sites}}},
  doi          = {{10.1074/jbc.m113.538470}},
  volume       = {{289}},
  year         = {{2014}},
}

@article{40219,
  author       = {{Wagenknecht, Inga and Meier-Gräwe, Uta}},
  issn         = {{1616-8836}},
  journal      = {{Zeitschrift für Paar-, Familien- und Sozialtherapie}},
  number       = {{2}},
  pages        = {{91--108}},
  publisher    = {{Psychosozial-Verlag}},
  title        = {{{Auf- und Ausbau Früher Hilfen in Zeiten knapper öffentlicher Kassen. Warum es sich lohnt, in Frühe Hilfen zu investieren}}},
  volume       = {{15}},
  year         = {{2014}},
}

@article{26910,
  abstract     = {{<jats:p>Non-alcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and obesity. Hence, carbohydrate quality could be of relevance to the risk of NAFLD, but prospective data are lacking. The aim of the present study was to investigate longitudinal associations between carbohydrate quality (including dietary glycaemic index (GI) and intakes of sugar, starch and fibre) and markers of liver function in an older Australian population. The analysis was based on 866 participants ( ≥ 49 years) of the Blue Mountains Eye Study with fasting blood specimens and dietary intake data at baseline and 5-year follow-up. Multi-level mixed regression analysis was used to relate dietary GI and sugar, starch and fibre intake to the liver enzymes alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT), as well as fasting TAG and HDL-cholesterol (HDL-C). After adjustment for potential confounding factors, a lower fibre intake was cross-sectionally related to higher GGT (<jats:italic>P</jats:italic>= 0·02) and fasting TAG (<jats:italic>P</jats:italic>= 0·002) levels, with fruit fibre being the most relevant fibre source (<jats:italic>P</jats:italic>= 0·095 for GGT; <jats:italic>P</jats:italic>= 0·003 for TAG). A higher dietary GI was associated with lower HDL-C (<jats:italic>P</jats:italic>= 0·046). Changes in carbohydrate quality during 5 years were not related to changes in ALT, GGT, TAG or HDL-C (<jats:italic>P</jats:italic>≥ 0·08). In conclusion, the absence of longitudinal associations between carbohydrate quality and liver enzymes and serum lipids in this older population does not support a major role of carbohydrate nutrition in liver function among the elderly.</jats:p>}},
  author       = {{Goletzke, Janina and Buyken, Anette and Gopinath, Bamini and Rochtchina, Elena and Barclay, Alan W. and Cheng, Guo and Brand-Miller, Jennie C. and Mitchell, Paul}},
  issn         = {{0007-1145}},
  journal      = {{British Journal of Nutrition}},
  pages        = {{918--925}},
  title        = {{{Carbohydrate quality is not associated with liver enzyme activity and plasma TAG and HDL concentrations over 5 years in an older population}}},
  doi          = {{10.1017/s0007114512005867}},
  year         = {{2013}},
}

@article{26911,
  author       = {{Goletzke, J. and Herder, C. and Joslowski, G. and Bolzenius, K. and Remer, T. and Wudy, S. A. and Roden, M. and Rathmann, W. and Buyken, Anette}},
  issn         = {{0149-5992}},
  journal      = {{Diabetes Care}},
  pages        = {{1870--1876}},
  title        = {{{Habitually Higher Dietary Glycemic Index During Puberty Is Prospectively Related to Increased Risk Markers of Type 2 Diabetes in Younger Adulthood}}},
  doi          = {{10.2337/dc12-2063}},
  year         = {{2013}},
}

@article{26912,
  author       = {{Joslowski, Gesa and Remer, Thomas and Assmann, Karen E. and Krupp, Danika and Cheng, Guo and Garnett, Sarah P. and Kroke, Anja and Wudy, Stefan A. and Günther, Anke L. B. and Buyken, Anette}},
  issn         = {{1541-6100}},
  journal      = {{The Journal of Nutrition}},
  pages        = {{1147--1154}},
  title        = {{{Animal Protein Intakes during Early Life and Adolescence Differ in Their Relation to the Growth Hormone-Insulin-Like-Growth-Factor Axis in Young Adulthood}}},
  doi          = {{10.3945/jn.113.175877}},
  year         = {{2013}},
}

@article{27043,
  abstract     = {{<jats:p>Dietary fat intake in childhood may influence the risk for developing chronic diseases. The objective of the present study was to examine secular trends in the parameters of fat intake between 2000 and 2010 in a sample of German children and adolescents (<jats:italic>n</jats:italic> 808) participating in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study. Dietary data from 4380 3 d weighed dietary records were analysed using repeated-measures regression to determine time trends in fat quantity, i.e. the intake of total fat, and in fat quality, i.e. the ratios of SFA, MUFA and PUFA. In young children (2–3 years) and in adolescents (13–18 years), total fat intake remained stable over time, but decreased by 0·08 % of total energy (%E) per year in 4–12-year-old children. In 2010, median fat intake was at the upper end of the recommendations. SFA intake decreased slightly in 2–3- and 4–12-year-old children by 0·09 and 0·05 %E per year, respectively. MUFA and PUFA intakes remained stable in all the age groups except in adolescents. Here, PUFA intake decreased initially, but increased between 2005 and 2010. In 2010, only between 3 and 18 % of the respective age groups had an intake of SFA or PUFA within the recommendations. In conclusion, fat quantity and quality did not change substantially between 2000 and 2010. Fat quality, in particular, needs to be improved, since a large percentage of our sample did not meet the recommended intakes for SFA and PUFA.</jats:p>}},
  author       = {{Libuda, Lars and Alexy, Ute and Kersting, Mathilde}},
  issn         = {{0007-1145}},
  journal      = {{British Journal of Nutrition}},
  pages        = {{141--150}},
  title        = {{{Time trends in dietary fat intake in a sample of German children and adolescents between 2000 and 2010: not quantity, but quality is the issue}}},
  doi          = {{10.1017/s0007114513002031}},
  year         = {{2013}},
}

@article{27061,
  author       = {{Libuda, Lars and Stimming, Madlen and Mesch, Christina and Warschburger, Petra and Kalhoff, Hermann and Koletzko, Berthold Viktor and Kersting, Mathilde}},
  issn         = {{1436-6207}},
  journal      = {{European Journal of Nutrition}},
  pages        = {{1335--1344}},
  title        = {{{Frequencies and demographic determinants of breastfeeding and DHA supplementation in a nationwide sample of mothers in Germany}}},
  doi          = {{10.1007/s00394-013-0633-4}},
  year         = {{2013}},
}

@article{27062,
  author       = {{Müller, Katrin and Libuda, Lars and Diethelm, Katharina and Huybrechts, Inge and Moreno, Luis A. and Manios, Yannis and Mistura, Lorenza and Dallongeville, Jean and Kafatos, Anthony and González-Gross, Marcela and Cuenca-García, Magdalena and Sjöström, Michael and Hallström, Lena and Widhalm, Kurt and Kersting, Mathilde}},
  issn         = {{0195-6663}},
  journal      = {{Appetite}},
  pages        = {{332--339}},
  title        = {{{Lunch at school, at home or elsewhere. Where do adolescents usually get it and what do they eat? Results of the HELENA Study}}},
  doi          = {{10.1016/j.appet.2013.09.002}},
  year         = {{2013}},
}

@article{27063,
  author       = {{Müller, K and Libuda, Lars and Gawehn, N and Drossard, C and Bolzenius, K and Kunz, C and Kersting, M}},
  issn         = {{0954-3007}},
  journal      = {{European Journal of Clinical Nutrition}},
  pages        = {{185--189}},
  title        = {{{Effects of lunch on children’s short-term cognitive functioning: a randomized crossover study}}},
  doi          = {{10.1038/ejcn.2012.209}},
  year         = {{2013}},
}