@article{22926, abstract = {{Implant-associated infections are an increasingly severe burden on healthcare systems worldwide and many research activities currently focus on inhibiting microbial colonization of biomedically relevant surfaces. To obtain molecular-level understanding of the involved processes and interactions, we investigate the adsorption of synthetic adhesin-like peptide sequences derived from the type IV pili of the Pseudomonas aeruginosa strains PAK and PAO at abiotic model surfaces, i.e., Au, SiO2, and oxidized Ti. These peptides correspond to the sequences of the receptor-binding domain 128–144 of the major pilin protein, which is known to facilitate P. aeruginosa adhesion at biotic and abiotic surfaces. Using quartz crystal microbalance with dissipation monitoring (QCM-D), we find that peptide adsorption is material- as well as strain-dependent. At the Au surface, PAO(128–144) shows drastically stronger adsorption than PAK(128–144), whereas adsorption of both peptides is markedly reduced at the oxide surfaces with less drastic differences between the two sequences. These observations suggest that peptide adsorption is influenced by not only the peptide sequence, but also peptide conformation. Our results furthermore highlight the importance of molecular-level investigations to understand and ultimately control microbial colonization of surfaces.}}, author = {{Yang, Yu and Schwiderek, Sabrina and Grundmeier, Guido and Keller, Adrian}}, issn = {{2673-8023}}, journal = {{Micro}}, number = {{1}}, pages = {{129--139}}, title = {{{Strain-Dependent Adsorption of Pseudomonas aeruginosa-Derived Adhesin-like Peptides at Abiotic Surfaces}}}, doi = {{10.3390/micro1010010}}, volume = {{1}}, year = {{2021}}, } @article{23023, abstract = {{DNA origami nanostructures (DONs) are promising substrates for the single-molecule investigation of biomolecular reactions and dynamics by in situ atomic force microscopy (AFM). For this, they are typically immobilized on mica substrates by adding millimolar concentrations of Mg2+ ions to the sample solution, which enable the adsorption of the negatively charged DONs at the like-charged mica surface. These non-physiological Mg2+ concentrations, however, present a serious limitation in such experiments as they may interfere with the reactions and processes under investigation. Therefore, we here evaluate three approaches to efficiently immobilize DONs at mica surfaces under essentially Mg2+-free conditions. These approaches rely on the pre-adsorption of different multivalent cations, i.e., Ni2+, poly-l-lysine (PLL), and spermidine (Spdn). DON adsorption is studied in phosphate-buffered saline (PBS) and pure water. In general, Ni2+ shows the worst performance with heavily deformed DONs. For 2D DON triangles, adsorption at PLL- and in particular Spdn-modified mica may outperform even Mg2+-mediated adsorption in terms of surface coverage, depending on the employed solution. For 3D six-helix bundles, less pronounced differences between the individual strategies are observed. Our results provide some general guidance for the immobilization of DONs at mica surfaces under Mg2+-free conditions and may aid future in situ AFM studies.}}, author = {{Xin, Yang and Zargariantabrizi, Amir Ardalan and Grundmeier, Guido and Keller, Adrian}}, issn = {{1420-3049}}, journal = {{Molecules}}, pages = {{4798}}, title = {{{Magnesium-Free Immobilization of DNA Origami Nanostructures at Mica Surfaces for Atomic Force Microscopy}}}, doi = {{10.3390/molecules26164798}}, volume = {{26}}, year = {{2021}}, } @inproceedings{21717, author = {{Schmolke, Tobias and Teutenberg, Dominik and Meschut, Gerson and Meinderink, Dennis and Koch, Leon and Ebbert, Christoph and Grundmeier, Guido}}, location = {{Online Event}}, title = {{{Entwicklung einer Methode zur Bewertung einer stahlintensiven Mischbau-Klebverbindung eines Batteriegehäuses gegenüber mechanischer und medialer Belastung und Berücksichtigung der Interphasenstruktur}}}, year = {{2021}}, } @article{22003, abstract = {{AbstractThe coherent electron spin dynamics of an ensemble of singly charged (In,Ga)As/GaAs quantum dots in a transverse magnetic field is driven by periodic optical excitation at 1 GHz repetition frequency. Despite the strong inhomogeneity of the electron g factor, the spectral spread of optical transitions, and the broad distribution of nuclear spin fluctuations, we are able to push the whole ensemble of excited spins into a single Larmor precession mode that is commensurate with the laser repetition frequency. Furthermore, we demonstrate that an optical detuning of the pump pulses from the probed optical transitions induces a directed dynamic nuclear polarization and leads to a discretization of the total magnetic field acting on the electron ensemble. Finally, we show that the highly periodic optical excitation can be used as universal tool for strongly reducing the nuclear spin fluctuations and preparation of a robust nuclear environment for subsequent manipulation of the electron spins, also at varying operation frequencies.}}, author = {{Evers, E. and Kopteva, N. E. and Yugova, I. A. and Yakovlev, D. R. and Reuter, Dirk and Wieck, A. D. and Bayer, M. and Greilich, A.}}, issn = {{2056-6387}}, journal = {{npj Quantum Information}}, title = {{{Suppression of nuclear spin fluctuations in an InGaAs quantum dot ensemble by GHz-pulsed optical excitation}}}, doi = {{10.1038/s41534-021-00395-1}}, year = {{2021}}, } @article{22004, author = {{Schall, Johannes and Deconinck, Marielle and Bart, Nikolai and Florian, Matthias and Helversen, Martin and Dangel, Christian and Schmidt, Ronny and Bremer, Lucas and Bopp, Frederik and Hüllen, Isabell and Gies, Christopher and Reuter, Dirk and Wieck, Andreas D. and Rodt, Sven and Finley, Jonathan J. and Jahnke, Frank and Ludwig, Arne and Reitzenstein, Stephan}}, issn = {{2511-9044}}, journal = {{Advanced Quantum Technologies}}, title = {{{Bright Electrically Controllable Quantum‐Dot‐Molecule Devices Fabricated by In Situ Electron‐Beam Lithography}}}, doi = {{10.1002/qute.202100002}}, year = {{2021}}, } @article{28255, abstract = {{Topological photonic crystals (TPhCs) provide robust manipulation of light with built-in immunity to fabrication tolerances and disorder. Recently, it was shown that TPhCs based on weak topology with a dislocation inherit this robustness and further host topologically protected lower-dimensional localized modes. However, TPhCs with weak topology at optical frequencies have not been demonstrated so far. Here, we use scattering-type scanning near-field optical microscopy to verify mid-bandgap zero-dimensional light localization close to 100 THz in a TPhC with nontrivial Zak phase and an edge dislocation. We show that because of the weak topology, differently extended dislocation centers induce similarly strong light localization. The experimental results are supported by full-field simulations. Along with the underlying fundamental physics, our results lay a foundation for the application of TPhCs based on weak topology in active topological nanophotonics, and nonlinear and quantum optic integrated devices because of their strong and robust light localization.}}, author = {{Lu, Jinlong and Wirth, Konstantin G. and Gao, Wenlong and Heßler, Andreas and Sain, Basudeb and Taubner, Thomas and Zentgraf, Thomas}}, issn = {{2375-2548}}, journal = {{Science Advances}}, number = {{49}}, title = {{{Observing 0D subwavelength-localized modes at ~100 THz protected by weak topology}}}, doi = {{10.1126/sciadv.abl3903}}, volume = {{7}}, year = {{2021}}, } @article{26719, abstract = {{AbstractThe interaction of acute exercise and the central nervous system evokes increasing interest in interdisciplinary research fields of neuroscience. Novel approaches allow to monitor large-scale brain networks from mobile electroencephalography (EEG) applying graph theory, but it is yet uncertain whether brain graphs extracted after exercise are reliable. We therefore aimed to investigate brain graph reliability extracted from resting state EEG data before and after submaximal exercise twice within one week in male participants. To obtain graph measures, we extracted global small-world-index (SWI), clustering coefficient (CC) and characteristic path length (PL) based on weighted phase leg index (wPLI) and spectral coherence (Coh) calculation. For reliability analysis, Intraclass-Correlation-Coefficient (ICC) and Coefficient of Variation (CoV) were computed for graph measures before (REST) and after POST) exercise. Overall results revealed poor to excellent measures at PRE and good to excellent ICCs at POST in the theta, alpha-1 and alpha-2, beta-1 and beta-2 frequency band. Based on bootstrap-analysis, a positive effect of exercise on reliability of wPLI based measures was observed, while exercise induced a negative effect on reliability of Coh-based graph measures. Findings indicate that brain graphs are a reliable tool to analyze brain networks in exercise contexts, which might be related to the neuroregulating effect of exercise inducing functional connections within the connectome. Relative and absolute reliability demonstrated good to excellent reliability after exercise. Chosen graph measures may not only allow analysis of acute, but also longitudinal studies in exercise-scientific contexts. }}, author = {{Büchel, Daniel and Lehmann, Tim and Sandbakk, Øyvind and Baumeister, Jochen}}, issn = {{2045-2322}}, journal = {{Scientific Reports}}, title = {{{EEG-derived brain graphs are reliable measures for exploring exercise-induced changes in brain networks}}}, doi = {{10.1038/s41598-021-00371-x}}, year = {{2021}}, } @article{22220, abstract = {{Abstract Developing resource-abundant and sustainable metal-free bifunctional oxygen electrocatalysts is essential for the practical application of zinc–air batteries (ZABs). 2D black phosphorus (BP) with fully exposed atoms and active lone pair electrons can be promising for oxygen electrocatalysts, which, however, suffers from low catalytic activity and poor electrochemical stability. Herein, guided by density functional theory (DFT) calculations, an efficient metal-free electrocatalyst is demonstrated via covalently bonding BP nanosheets with graphitic carbon nitride (denoted BP-CN-c). The polarized PN covalent bonds in BP-CN-c can efficiently regulate the electron transfer from BP to graphitic carbon nitride and significantly promote the OOH* adsorption on phosphorus atoms. Impressively, the oxygen evolution reaction performance of BP-CN-c (overpotential of 350 mV at 10 mA cm−2, 90\% retention after 10 h operation) represents the state-of-the-art among the reported BP-based metal-free catalysts. Additionally, BP-CN-c exhibits a small half-wave overpotential of 390 mV for oxygen reduction reaction, representing the first bifunctional BP-based metal-free oxygen catalyst. Moreover, ZABs are assembled incorporating BP-CN-c cathodes, delivering a substantially higher peak power density (168.3 mW cm−2) than the Pt/C+RuO2-based ZABs (101.3 mW cm−2). The acquired insights into interfacial covalent bonds pave the way for the rational design of new and affordable metal-free catalysts.}}, author = {{Wang, Xia and Kormath Madam Raghupathy, Ramya and Querebillo, Christine Joy and Liao, Zhongquan and Li, Dongqi and Lin, Kui and Hantusch, Martin and Sofer, Zdeněk and Li, Baohua and Zschech, Ehrenfried and Weidinger, Inez M. and Kühne, Thomas and Mirhosseini, Hossein and Yu, Minghao and Feng, Xinliang}}, journal = {{Advanced Materials}}, keywords = {{2D materials, bifunctional oxygen electrocatalysts, black phosphorus, oxygen evolution reaction, zinc–air batteries}}, number = {{20}}, pages = {{2008752}}, title = {{{Interfacial Covalent Bonds Regulated Electron-Deficient 2D Black Phosphorus for Electrocatalytic Oxygen Reactions}}}, doi = {{https://doi.org/10.1002/adma.202008752}}, volume = {{33}}, year = {{2021}}, } @article{29700, abstract = {{We have carried out an extensive search for stable polymorphs of carbon nitride with C3N5 stoichiometry using the minima hopping method. Contrary to the widely held opinion that stacked{,} planar{,} graphite-like structures are energetically the most stable carbon nitride polymorphs for various nitrogen contents{,} we find that this does not apply for nitrogen-rich materials owing to the high abundance of N–N bonds. In fact{,} our results disclose novel morphologies with moieties not previously considered for C3N5. We demonstrate that nitrogen-rich compounds crystallize in a large variety of different structures due to particular characteristics of their energy landscapes. The newly found low-energy structures of C3N5 have band gaps within good agreement with the values measured in experimental studies.}}, author = {{Ghasemi, Alireza and Mirhosseini, Hossein and Kühne, Thomas}}, journal = {{Phys. Chem. Chem. Phys.}}, pages = {{6422--6432}}, publisher = {{The Royal Society of Chemistry}}, title = {{{Thermodynamically stable polymorphs of nitrogen-rich carbon nitrides: a C3N5 study}}}, doi = {{10.1039/D0CP06185A}}, volume = {{23}}, year = {{2021}}, } @article{23701, author = {{Schoppa, Timo and Jung, Dimitri and Rust, Tarik and Mulac, Dennis and Kuckling, Dirk and Langer, Klaus}}, issn = {{0378-5173}}, journal = {{International Journal of Pharmaceutics}}, publisher = {{Elsevier}}, title = {{{Light-responsive polymeric nanoparticles based on a novel nitropiperonal based polyester as drug delivery systems for photosensitizers in PDT}}}, doi = {{10.1016/j.ijpharm.2021.120326}}, volume = {{597}}, year = {{2021}}, } @article{23662, author = {{Rust, Tarik and Jung, Dimitri and Hoppe, Axel and Schoppa, Timo and Langer, Klaus and Kuckling, Dirk}}, issn = {{2637-6105}}, journal = {{ACS Applied Polymer Materials}}, number = {{8}}, pages = {{3831--3842}}, publisher = {{ACS}}, title = {{{Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery}}}, doi = {{10.1021/acsapm.1c00411}}, volume = {{3}}, year = {{2021}}, } @article{23699, author = {{Schmiegel, Carsten J. and Baier, Rene and Kuckling, Dirk}}, issn = {{1434-193X}}, journal = {{European Journal of Organic Chemistry}}, pages = {{2578--2586}}, publisher = {{Wiley-VCH}}, title = {{{Direct Asymmetric Aldol Reaction in Continuous Flow Using Gel‐Bound Organocatalysts}}}, doi = {{10.1002/ejoc.202100268}}, year = {{2021}}, } @article{31022, author = {{Abdelaty, Momen S. A. and Kuckling, Dirk}}, issn = {{0303-402X}}, journal = {{Colloid and Polymer Science}}, keywords = {{Materials Chemistry, Colloid and Surface Chemistry, Polymers and Plastics, Physical and Theoretical Chemistry}}, number = {{10}}, pages = {{1617--1629}}, publisher = {{Springer Science and Business Media LLC}}, title = {{{Altering of lower critical solution temperature of environmentally responsive poly (N-isopropylacrylamide-co-acrylic acid-co-vanillin acrylate) affected by acrylic acid, vanillin acrylate, and post-polymerization modification}}}, doi = {{10.1007/s00396-021-04882-x}}, volume = {{299}}, year = {{2021}}, } @article{31019, author = {{Watt, Fabian A. and Sieland, Benedikt and Dickmann, Nicole and Schoch, Roland and Herbst-Irmer, Regine and Ott, Holger and Paradies, Jan and Kuckling, Dirk and Hohloch, Stephan}}, issn = {{1477-9226}}, journal = {{Dalton Transactions}}, keywords = {{Inorganic Chemistry}}, number = {{46}}, pages = {{17361--17371}}, publisher = {{Royal Society of Chemistry (RSC)}}, title = {{{Coupling of CO2 and epoxides catalysed by novel N-fused mesoionic carbene complexes of nickel(ii)}}}, doi = {{10.1039/d1dt03311e}}, volume = {{50}}, year = {{2021}}, } @article{23702, author = {{Schmiegel, Carsten J. and Berg, Patrik and Obst, Franziska and Schoch, Roland and Appelhans, Dietmar and Kuckling, Dirk}}, issn = {{1434-193X}}, journal = {{European Journal of Organic Chemistry}}, number = {{11}}, pages = {{1628--1636}}, publisher = {{Wiley-VCH}}, title = {{{Continuous Flow Synthesis of Azoxybenzenes by Reductive Dimerization of Nitrosobenzenes with Gel‐Bound Catalysts}}}, doi = {{10.1002/ejoc.202100006}}, year = {{2021}}, } @article{23696, author = {{Jung, Dimitri and Rust, Tarik and Völlmecke, Katharina and Schoppa, Timo and Langer, Klaus and Kuckling, Dirk}}, issn = {{1759-9954}}, journal = {{Polymer Chemistry}}, pages = {{4565--4575}}, publisher = {{RSC}}, title = {{{Backbone vs. side-chain: two light-degradable polyurethanes based on 6-nitropiperonal}}}, doi = {{10.1039/d1py00442e}}, volume = {{12}}, year = {{2021}}, } @article{23698, author = {{Rodin, Maksim and Li, Jie and Kuckling, Dirk}}, issn = {{0306-0012}}, journal = {{Chemical Society Reviews}}, pages = {{8147--8177}}, publisher = {{RSC}}, title = {{{Dually cross-linked single networks: structures and applications}}}, doi = {{10.1039/d0cs01585g}}, volume = {{50}}, year = {{2021}}, } @article{33653, author = {{Gurinov, Andrei and Sieland, Benedikt and Kuzhelev, Andrey and Elgabarty, Hossam and Kühne, Thomas and Prisner, Thomas and Paradies, Jan and Baldus, Marc and Ivanov, Konstantin L. and Pylaeva, Svetlana}}, issn = {{1433-7851}}, journal = {{Angewandte Chemie International Edition}}, keywords = {{General Chemistry, Catalysis}}, number = {{28}}, pages = {{15371--15375}}, publisher = {{Wiley}}, title = {{{Mixed‐Valence Compounds as Polarizing Agents for Overhauser Dynamic Nuclear Polarization in Solids}}}, doi = {{10.1002/anie.202103215}}, volume = {{60}}, year = {{2021}}, } @article{32453, abstract = {{Context: Only 55% of the athletes return to competitive sports after an anterior cruciate ligament (ACL) injury. Athletes younger than 25 years who return to sports have a second injury rate of 23%. There may be a mismatch between rehabilitation contents and the demands an athlete faces after returning to sports. Current return-to-sports (RTS) tests utilize closed and predictable motor skills; however, demands on the field are different. Neurocognitive functions are essential to manage dynamic sport situations and may fluctuate after peripheral injuries. Most RTS and rehabilitation paradigms appear to lack this aspect, which might be linked to increased risk of second injury. Objective: This systematic and scoping review aims to map existing evidence about neurocognitive and neurophysiological functions in athletes, which could be linked to ACL injury in an integrated fashion and bring an extensive perspective to assessment and rehabilitation approaches. Data Sources: PubMed and Cochrane databases were searched to identify relevant studies published between 2005 and 2020 using the keywords ACL, brain, cortical, neuroplasticity, cognitive, cognition, neurocognition, and athletes. Study Selection: Studies investigating either neurocognitive or neurophysiological functions in athletes and linking these to ACL injury regardless of their design and technique were included. Study Design: Systematic review. Level of Evidence: Level 3. Data Extraction: The demographic, temporal, neurological, and behavioral data revealing possible injury-related aspects were extracted and summarized. Results: A total of 16 studies were included in this review. Deficits in different neurocognitive domains and changes in neurophysiological functions could be a predisposing risk factor for, or a consequence caused by, ACL injuries. Conclusion: Clinicians should view ACL injuries not only as a musculoskeletal but also as a neural lesion with neurocognitive and neurophysiological aspects. Rehabilitation and RTS paradigms should consider these changes for assessment and interventions after injury. }}, author = {{Piskin, Daghan and Benjaminse, Anne and Dimitrakis, Panagiotis and Gokeler, Alli}}, issn = {{1941-7381}}, journal = {{Sports Health: A Multidisciplinary Approach}}, keywords = {{Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine}}, number = {{4}}, pages = {{549--555}}, publisher = {{SAGE Publications}}, title = {{{Neurocognitive and Neurophysiological Functions Related to ACL Injury: A Framework for Neurocognitive Approaches in Rehabilitation and Return-to-Sports Tests}}}, doi = {{10.1177/19417381211029265}}, volume = {{14}}, year = {{2021}}, } @article{32451, abstract = {{Athletes in team sports have to quickly visually perceive actions of opponents and teammates while executing their own movements. These continuous actions are performed under time pressure and may contribute to a non-contact ACL injury. However, ACL injury screening and prevention programmes are primarily based on standardised movements in a predictable environment. The sports environment provides much greater cognitive demand because athletes must attend their attention to numerous external stimuli and inhibit impulsive actions. Any deficit or delay in attentional processing may contribute to an inability to correct potential errors in complex coordination, resulting in knee positions that increase the ACL injury risk. In this viewpoint, we advocate that ACL injury screening should include the sports specific neurocognitive demands.}}, author = {{Gokeler, Alli and Benjaminse, Anne and Della Villa, Francesco and Tosarelli, Fillippo and Verhagen, Evert and Baumeister, Jochen}}, issn = {{2055-7647}}, journal = {{BMJ Open Sport & Exercise Medicine}}, keywords = {{Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine}}, number = {{2}}, publisher = {{BMJ}}, title = {{{Anterior cruciate ligament injury mechanisms through a neurocognition lens: implications for injury screening}}}, doi = {{10.1136/bmjsem-2021-001091}}, volume = {{7}}, year = {{2021}}, }