@article{35334, author = {{Bilalov, Azat and Elsing, Jonas and Haas, Eva and Schmidt, Claudia and Olsson, Ulf}}, issn = {{0021-9797}}, journal = {{Journal of Colloid and Interface Science}}, keywords = {{Colloid and Surface Chemistry, Surfaces, Coatings and Films, Biomaterials, Electronic, Optical and Magnetic Materials}}, pages = {{360--367}}, publisher = {{Elsevier BV}}, title = {{{Embedding DNA in surfactant mesophases: The phase diagram of the ternary system dodecyltrimethylammonium–DNA/monoolein/water in comparison to the DNA-free analogue}}}, doi = {{10.1016/j.jcis.2012.11.067}}, volume = {{394}}, year = {{2012}}, } @article{35340, author = {{Stubenrauch, Cosima and Kleinschmidt, Felix and Schmidt, Claudia}}, issn = {{0743-7463}}, journal = {{Langmuir}}, keywords = {{Electrochemistry, Spectroscopy, Surfaces and Interfaces, Condensed Matter Physics, General Materials Science}}, number = {{25}}, pages = {{9206--9210}}, publisher = {{American Chemical Society (ACS)}}, title = {{{Structural Evolution in the Isotropic Channel of a Water–Nonionic Surfactant System That Has a Disconnected Lamellar Phase: A 1H NMR Self-Diffusion Study}}}, doi = {{10.1021/la301948d}}, volume = {{28}}, year = {{2012}}, } @article{35335, author = {{Quiñones, Javier Pérez and Gothelf, Kurt Vesterager and Kjems, Jørgen and Caballero, Ángeles María Heras and Schmidt, Claudia and Covas, Carlos Peniche}}, issn = {{0144-8617}}, journal = {{Carbohydrate Polymers}}, keywords = {{Materials Chemistry, Polymers and Plastics, Organic Chemistry}}, number = {{1}}, pages = {{143--151}}, publisher = {{Elsevier BV}}, title = {{{N,O6-partially acetylated chitosan nanoparticles hydrophobically-modified for controlled release of steroids and vitamin E}}}, doi = {{10.1016/j.carbpol.2012.07.080}}, volume = {{91}}, year = {{2012}}, } @article{35339, author = {{Quiñones, Javier Pérez and Gothelf, Kurt Vesterager and Kjems, Jørgen and Caballero, Ángeles María Heras and Schmidt, Claudia and Covas, Carlos Peniche}}, issn = {{0144-8617}}, journal = {{Carbohydrate Polymers}}, keywords = {{Materials Chemistry, Polymers and Plastics, Organic Chemistry}}, number = {{4}}, pages = {{1373--1377}}, publisher = {{Elsevier BV}}, title = {{{Self-assembled nanoparticles of glycol chitosan – Ergocalciferol succinate conjugate, for controlled release}}}, doi = {{10.1016/j.carbpol.2012.02.039}}, volume = {{88}}, year = {{2012}}, } @article{35337, author = {{Quiñones, Javier Pérez and Gothelf, Kurt Vesterager and Kjems, Jørgen and Yang, Chuanxu and Caballero, Angeles María Heras and Schmidt, Claudia and Covas, Carlos Peniche}}, issn = {{0144-8617}}, journal = {{Carbohydrate Polymers}}, keywords = {{Materials Chemistry, Polymers and Plastics, Organic Chemistry}}, number = {{1}}, pages = {{856--864}}, publisher = {{Elsevier BV}}, title = {{{Self-assembled nanoparticles of modified-chitosan conjugates for the sustained release of dl-α-tocopherol}}}, doi = {{10.1016/j.carbpol.2012.10.005}}, volume = {{92}}, year = {{2012}}, } @article{7493, author = {{Piegdon, K. A. and Lexow, M. and Grundmeier, G. and Kitzerow, Heinz-Siegfried and Pärschke, K. and Mergel, D. and Reuter, Dirk and Wieck, A. D. and Meier, Cedrik}}, issn = {{1094-4087}}, journal = {{Optics Express}}, number = {{6}}, publisher = {{The Optical Society}}, title = {{{All-optical tunability of microdisk lasers via photo-adressable polyelectrolyte functionalization}}}, doi = {{10.1364/oe.20.006060}}, volume = {{20}}, year = {{2012}}, } @article{7328, author = {{Piegdon, K. A. and Lexow, M. and Grundmeier, G. and Kitzerow, Heinz-Siegfried and Pärschke, K. and Mergel, D. and Reuter, Dirk and Wieck, A. D. and Meier, C.}}, issn = {{1094-4087}}, journal = {{Optics Express}}, number = {{6}}, publisher = {{The Optical Society}}, title = {{{All-optical tunability of microdisk lasers via photo-adressable polyelectrolyte functionalization}}}, doi = {{10.1364/oe.20.006060}}, volume = {{20}}, year = {{2012}}, } @article{4116, abstract = {{Anisotropic etching processes for mesa structure formation using fluorinated plasma atmospheres in an electron cyclotron resonance (ECR) plasma etcher were studied on Novasic substrates with 10 μm thick 3C-SiC(100) grown on Si(100). To achieve reasonable etching rates, a special gas inlet system suitable for injecting SF6 into the high density downstream Ar ECR plasma was designed. The influence of the etching mask material on the sidewall morphology was investigated. Masking materials with small grain sizes are preferable to achieve a desired shape. The evolution of the mesa form was investigated in dependence on the gas composition, the applied bias, the pressure and the composition of the gas atmosphere. The achieved sidewall slope was 84.5 deg. The aspect ratios of the fabricated structures in the developed residue free ECR plasma etching process were between 5 and 10. Mesa structures aligned to [100] and [110] directions were fabricated.}}, author = {{Hiller, Lars and Stauden, Thomas and Kemper, Ricarda M. and Lindner, Jörg and As, Donat J. and Pezoldt, Jörg}}, issn = {{1662-9752}}, journal = {{Materials Science Forum}}, location = {{Cleveland (USA)}}, pages = {{901--904}}, publisher = {{Trans Tech Publications}}, title = {{{ECR-Ectching of Submicron and Nanometer Sized 3C-SiC(100) Mesa Structures}}}, doi = {{10.4028/www.scientific.net/msf.717-720.901}}, volume = {{717-720}}, year = {{2012}}, } @article{29674, author = {{Heinzmann, U and Gryzia, A and Helmstedt, A and Dohmeier, N and Predatsch, H and Brechling, A and Müller, N and Sacher, Marc and Hoeke, V and Krickemeyer, E and Glaser, T and Bouvron, S and Fonin, M and Neumann, M}}, issn = {{1742-6588}}, journal = {{Journal of Physics: Conference Series}}, keywords = {{General Physics and Astronomy}}, number = {{2}}, publisher = {{IOP Publishing}}, title = {{{The adsorption, stability and properties of Mn6Cr Single-Molecule-Magnets studied by means of nc-AFM, STM, XAS and Spin-resolved Photoelectron Spectroscopy}}}, doi = {{10.1088/1742-6596/388/2/022013}}, volume = {{388}}, year = {{2012}}, } @article{54937, abstract = {{Purpose: The epithelial sodium channel (ENaC) is typically expressed in sodium-absorbing epithelia. Several reports suggest that ENaC is also expressed in ocular tissues and may play a role in aqueous humor secretion and glaucoma. However, the precise localization of ENaC in the human eye is still unclear. Here, the authors studied ENaC expression in 12 normal human donor eyes and in six eyes of patients with glaucoma. Methods: Quantitative real-time PCR was used to investigate the expression of $\alpha$-, $\beta$-, $\gamma$-, and $\delta$-ENaC transcripts in ocular tissues. In addition, the authors performed immunohistochemical studies using recently generated antibodies against human $\beta$- and $\gamma$-ENaC. Results: At the mRNA level, all four ENaC subunits were found to be expressed in a wide range of ocular tissues from normal and glaucomatous human eyes, with the cornea, ciliary body, iris, and retina showing the highest expression levels. At the protein level, $\beta$- and $\gamma$-ENaC subunits showed distinct distribution patterns and could be immunolocalized primarily to the cell membranes of epithelial cells of the cornea and to the conjunctiva, iris, ciliary body, lens, and retinal pigment epithelium but also to vascular endothelial cells, smooth muscle cells, stromal cells, and retinal neurons. The authors found no altered mRNA level of any subunit in glaucomatous eyes. Conclusions: All four ENaC subunits ($\alpha$$\beta$$\gamma$$\delta$) are expressed in the normal human eye, with distinct localization of subunits possibly reflecting different functional states of the channel. The (patho-)physiological roles of ENaC in the various localizations in the eye remain to be determined.}}, author = {{Krueger, Bettina and Schlötzer-Schrehardt, Ursula and Haerteis, Silke and Zenkel, Matthias and Chankiewitz, Verena E. and Amann, Kerstin U. and Kruse, Friedrich E. and Korbmacher, Christoph}}, journal = {{Investigative Opthalmology & Visual Science}}, number = {{2}}, pages = {{596–604}}, publisher = {{Association for Research in Vision and Ophthalmology (ARVO)}}, title = {{{Four Subunits ($\alpha$$\beta$$\gamma$$\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations}}}, doi = {{10.1167/iovs.11-8581}}, volume = {{53}}, year = {{2012}}, } @article{54930, abstract = {{Background: Increased expression of the pro-fibrotic protein connective tissue growth factor (CTGF) has been detected in injured kidneys and elevated urinary levels of CTGF are discussed as prognostic marker of chronic kidney disease. There is evidence that epithelial cells lining the renal tubular system contribute to uptake and secretion of CTGF. However, the role of different types of tubular epithelial cells in these processes so far has not been addressed in primary cultures of human cells. Results: Tubular epithelial cells of proximal and distal origin were isolated from human kidneys and cultured as polarized cells in insert wells. The pro-fibrotic stimuli lysophosphatidic acid (LPA) and transforming growth factor $\beta$ (TGF-$\beta$) were used to induce CTGF secretion.LPA activated CTGF secretion in proximal tubular cells when applied from either the apical or the basolateral side as shown by immunocytochemistry. CTGF was secreted exclusively to the apical side. Signaling pathways activated by LPA included MAP kinase and Rho kinase signaling. TGF-$\beta$ applied from either side also stimulated CTGF secretion primarily to the apical side with little basolateral release.Interestingly, TGF-$\beta$ activation induced different signaling pathways depending on the side of TGF-$\beta$ application. Smad signaling was almost exclusively activated from the basolateral side most prominently in cells of distal origin. Only part of these cells also synthesized CTGF indicating that Smad activation alone was not sufficient for CTGF induction. MAP kinases were involved in apical TGF-$\beta$-mediated activation of CTGF synthesis in proximal cells and a subset of epithelial cells of distal origin. This subpopulation of distal tubular cells was also able to internalize recombinant apical CTGF, in addition to proximal cells which were the main cells to take up exogenous CTGF. Conclusions: Analysis of polarized human primary renal epithelial cells in a transwell system shows that vectorial secretion of the pro-fibrotic protein CTGF depends on the cell type, the stimulus and the signaling pathway activated. In all conditions, CTGF was secreted mainly to the apical side upon TGF-$\beta$ and LPA treatment and therefore, likely contributes to increased urinary CTGF levels in vivo. Moreover, CTGF secreted basolaterally may be active as paracrine pro-fibrotic mediator.}}, author = {{Zuehlke, Jonathan and Ebenau, Astrid and Krueger, Bettina and Goppelt-Struebe, Margarete}}, journal = {{Cell Communication and Signaling}}, number = {{1}}, publisher = {{Springer}}, title = {{{Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\beta$ in human tubular epithelial cells}}}, doi = {{10.1186/1478-811x-10-25}}, volume = {{10}}, year = {{2012}}, } @article{54934, abstract = {{Aldosterone is thought to be the main hormone to stimulate the epithelial sodium channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) comprising the late distal convoluted tubule (DCT2), the connecting tubule (CNT) and the entire collecting duct (CD). There is immunohistochemical evidence for an axial gradient of ENaC expression along the ASDN with highest expression in the DCT2 and CNT. However, most of our knowledge about renal ENaC function stems from studies in the cortical collecting duct (CCD). Here we investigated ENaC function in the transition zone of DCT2/CNT or CNT/CCD microdissected from mice maintained on different sodium diets to vary plasma aldosterone levels. Single-channel recordings demonstrated amiloride-sensitive Na(+) channels in DCT2/CNT with biophysical properties typical for ENaC previously described in CNT/CCD. In animals maintained on a standard salt diet, the average ENaC-mediated whole cell current ($\Delta$I(ami)) was higher in DCT2/CNT than in CNT/CCD. A low salt diet increased $\Delta$I(ami) in CNT/CCD but had little effect on $\Delta$I(ami) in DCT2/CNT. To investigate whether aldosterone is necessary for ENaC activity in the DCT2/CNT, we used aldosterone synthase knockout (AS(-/-)) mice that lack aldosterone. In CNT/CCD of AS(-/-) mice, $\Delta$I(ami) was lower than that in wild-type (WT) animals and was not stimulated by a low salt diet. In contrast, in DCT2/CNT of AS(-/-) mice, $\Delta$I(ami) was similar to that in DCT2/CNT of WT animals both on a standard and on a low salt diet. We conclude that ENaC function in the DCT2/CNT is largely independent of aldosterone which is in contrast to its known aldosterone sensitivity in CNT/CCD.}}, author = {{Nesterov, Viatcheslav and Dahlmann, Anke and Krueger, Bettina and Bertog, Marko and Loffing, Johannes and Korbmacher, Christoph}}, journal = {{American Journal of Physiology-Renal Physiology}}, number = {{9}}, pages = {{F1289–F1299}}, publisher = {{American Physiological Society}}, title = {{{Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron}}}, doi = {{10.1152/ajprenal.00247.2012}}, volume = {{303}}, year = {{2012}}, } @article{54939, abstract = {{Background: Renal tubular epithelial cells of proximal and distal origin differ markedly in their physiological functions. Therefore, we hypothesized that they also differ in their capacity to undergo epithelial to mesenchymal alterations. Results: We used cultures of freshly isolated primary human tubular cells. To distinguish cells of different tubular origin we took advantage of the fact that human proximal epithelial cells uniquely express N-cadherin instead of E-cadherin as major cell-cell adhesion molecule. To provoke mesenchymal alteration we treated these cocultures with TGF-$\beta$ for up to 6 days. Within this time period, the morphology of distal tubular cells was barely altered. In contrast to tubular cell lines, E-cadherin was not down-regulated by TGF-$\beta$, even though TGF-$\beta$ signal transduction was initiated as demonstrated by nuclear localization of Smad2/3. Analysis of transcription factors and miRNAs possibly involved in E-cadherin regulation revealed high levels of miRNAs of the miR200-family, which may contribute to the stability of E-cadherin expression in human distal tubular epithelial cells. By contrast, proximal tubular epithelial cells altered their phenotype when treated with TGF-$\beta$. They became elongated and formed three-dimensional structures. Rho-kinases were identified as modulators of TGF-$\beta$-induced morphological alterations. Non-specific inhibition of Rho-kinases resulted in stabilization of the epithelial phenotype, while partial effects were observed upon downregulation of Rho-kinase isoforms ROCK1 and ROCK2. The distinct reactivity of proximal and distal cells was retained when the cells were cultured as polarized cells. Conclusions: Interference with Rho-kinase signaling provides a target to counteract TGF-$\beta$-mediated mesenchymal alterations of epithelial cells, particularly in proximal tubular epithelial cells. Furthermore, primary distal tubular cells differed from cell lines by their high phenotypic stability which included constant expression of E-cadherin. Our cell culture system of primary epithelial cells is thus suitable to understand and modulate cellular remodeling processes of distinct tubular cells relevant for human renal disease.}}, author = {{Keller, Christof and Kroening, Sven and Zuehlke, Jonathan and Kunath, Frank and Krueger, Bettina and Goppelt-Struebe, Margarete}}, issn = {{1932-6203}}, journal = {{PLOS ONE}}, number = {{8}}, pages = {{e43584}}, publisher = {{Public Library of Science}}, title = {{{Distinct Mesenchymal Alterations in N-Cadherin and E-Cadherin Positive Primary Renal Epithelial Cells}}}, doi = {{10.1371/journal.pone.0043584}}, volume = {{7}}, year = {{2012}}, } @inproceedings{54994, author = {{Wagner, Thorsten and Tiemann, Michael and Kohl, Claus-Dieter and Morandi, Sara and Malagù, Cesare and Donato, Nicola and Latino, Mariangela and Neri, Giovanni}}, booktitle = {{Proceedings IMCS 2012}}, publisher = {{AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany}}, title = {{{Mechanistic Model for UV light-enhanced NO2 Sensing utilizing Ordered Mesoporous In2O3}}}, doi = {{10.5162/imcs2012/p1.3.17}}, year = {{2012}}, } @inproceedings{54995, author = {{Klaus, Dominik and Tiemann, Michael and Wagner, Thorsten}}, booktitle = {{Proceedings IMCS 2012}}, publisher = {{AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany}}, title = {{{Nanostructured Metal Oxides for High-Temperature Gas Sensing: Structural Stabilization in Porous Metal Oxides}}}, doi = {{10.5162/imcs2012/p2.0.3}}, year = {{2012}}, } @article{28890, author = {{Grimminger-Seidensticker, Elke and Gieß-Stüber, P.}}, journal = {{Revue d´Allemagne et des Pays de Langue Allemande}}, number = {{4}}, pages = {{521--534}}, title = {{{Integration im und durch Sport. Die sportpolitische Programmatik in Deutschland aus sportwissenschaftlicher Perspektive}}}, volume = {{44}}, year = {{2012}}, } @article{28892, author = {{Grimminger-Seidensticker, Elke}}, journal = {{Journal of Physical Education and Health. Social Perspective}}, number = {{1}}, pages = {{5--14}}, title = {{{An Empirical Study About the Importance of Teachers´ Educational Beliefs and Acculturation Attitudes for the Implementation of Intercultural Education in Physical Education}}}, volume = {{1}}, year = {{2012}}, } @article{28891, author = {{Grimminger-Seidensticker, Elke}}, journal = {{Sportwissenschaft}}, number = {{2}}, pages = {{105--114}}, title = {{{Anerkennungs- und Missachtungsprozesse im Sportunterricht. Die Bedeutung von Machtquellen für die Gestaltung sozialer Peer-Beziehungen}}}, volume = {{42}}, year = {{2012}}, } @article{22597, author = {{Banerjee, Manish and Srinivasan, Nagendra Babu and Zhu, Huaizhi and Kim, Sun Ja and Xu, Ke and Winter, Manuela and Becker, Hans-Werner and Rogalla, Detlef and de los Arcos de Pedro, Maria Teresa and Bekermann, Daniela and Barreca, Davide and Fischer, Roland A. and Devi, Anjana}}, issn = {{1528-7483}}, journal = {{Crystal Growth & Design}}, pages = {{5079--5089}}, title = {{{Fabrication of ZrO2 and ZrN Films by Metalorganic Chemical Vapor Deposition Employing New Zr Precursors}}}, doi = {{10.1021/cg3010147}}, year = {{2012}}, } @article{22602, author = {{Milanov, Andrian P. and Xu, Ke and Cwik, Stefan and Parala, Harish and de los Arcos de Pedro, Maria Teresa and Becker, Hans-Werner and Rogalla, Detlef and Cross, Richard and Paul, Shashi and Devi, Anjana}}, issn = {{1477-9226}}, journal = {{Dalton Transactions}}, title = {{{Sc2O3, Er2O3, and Y2O3 thin films by MOCVD from volatile guanidinate class of rare-earth precursors}}}, doi = {{10.1039/c2dt31219k}}, year = {{2012}}, }