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Cross-education does not improve early and late-phase rehabilitation outcomes after ACL reconstruction: a randomized controlled clinical trial. <i>Knee Surg Sports Traumatol Arthrosc</i>. 2019;27(2):478-490. doi:<a href=\"https://doi.org/10.1007/s00167-018-5116-y\">10.1007/s00167-018-5116-y</a>","ieee":"T. Zult <i>et al.</i>, “Cross-education does not improve early and late-phase rehabilitation outcomes after ACL reconstruction: a randomized controlled clinical trial.,” <i>Knee Surg Sports Traumatol Arthrosc</i>, vol. 27, no. 2, pp. 478–490, 2019.","apa":"Zult, T., Gokeler, A., van Raay, J., Brouwer, R., Zijdewind, I., Farthing, J., &#38; Hortobágyi, T. (2019). 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Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths. <i>Langmuir</i>. 2019;35:12113-12122. doi:<a href=\"https://doi.org/10.1021/acs.langmuir.9b01515\">10.1021/acs.langmuir.9b01515</a>","mla":"Hämisch, Benjamin, et al. “Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths.” <i>Langmuir</i>, vol. 35, 2019, pp. 12113–22, doi:<a href=\"https://doi.org/10.1021/acs.langmuir.9b01515\">10.1021/acs.langmuir.9b01515</a>.","chicago":"Hämisch, Benjamin, Anne Büngeler, Charlotte Kielar, Adrian Keller, Oliver Strube, and Klaus Huber. “Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths.” <i>Langmuir</i> 35 (2019): 12113–22. <a href=\"https://doi.org/10.1021/acs.langmuir.9b01515\">https://doi.org/10.1021/acs.langmuir.9b01515</a>.","short":"B. Hämisch, A. Büngeler, C. Kielar, A. Keller, O. Strube, K. Huber, Langmuir 35 (2019) 12113–12122.","ieee":"B. Hämisch, A. Büngeler, C. Kielar, A. Keller, O. Strube, and K. Huber, “Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths,” <i>Langmuir</i>, vol. 35, pp. 12113–12122, 2019.","apa":"Hämisch, B., Büngeler, A., Kielar, C., Keller, A., Strube, O., &#38; Huber, K. (2019). Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths. <i>Langmuir</i>, <i>35</i>, 12113–12122. <a href=\"https://doi.org/10.1021/acs.langmuir.9b01515\">https://doi.org/10.1021/acs.langmuir.9b01515</a>"},"publication":"Langmuir","date_created":"2021-07-08T12:07:00Z","department":[{"_id":"302"},{"_id":"314"},{"_id":"387"}],"type":"journal_article","publication_identifier":{"issn":["0743-7463","1520-5827"]},"author":[{"first_name":"Benjamin","last_name":"Hämisch","full_name":"Hämisch, Benjamin"},{"full_name":"Büngeler, Anne","last_name":"Büngeler","first_name":"Anne"},{"full_name":"Kielar, Charlotte","first_name":"Charlotte","last_name":"Kielar"},{"full_name":"Keller, Adrian","orcid":"0000-0001-7139-3110","first_name":"Adrian","last_name":"Keller","id":"48864"},{"first_name":"Oliver","last_name":"Strube","full_name":"Strube, Oliver"},{"full_name":"Huber, Klaus","first_name":"Klaus","last_name":"Huber"}],"year":"2019","status":"public","title":"Self-Assembly of Fibrinogen in Aqueous, Thrombin-Free Solutions of Variable Ionic Strengths","intvolume":"        35","publication_status":"published","date_updated":"2022-01-06T06:55:38Z","language":[{"iso":"eng"}],"_id":"22652","page":"12113-12122","volume":35,"user_id":"48864","doi":"10.1021/acs.langmuir.9b01515"},{"year":"2019","title":"Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation","status":"public","publication_identifier":{"issn":["2040-3364","2040-3372"]},"author":[{"first_name":"Saminathan","last_name":"Ramakrishnan","full_name":"Ramakrishnan, Saminathan"},{"full_name":"Schärfen, Leonard","first_name":"Leonard","last_name":"Schärfen"},{"full_name":"Hunold, Kristin","first_name":"Kristin","last_name":"Hunold"},{"full_name":"Fricke, Sebastian","first_name":"Sebastian","last_name":"Fricke"},{"first_name":"Guido","last_name":"Grundmeier","full_name":"Grundmeier, Guido","id":"194"},{"first_name":"Michael","last_name":"Schlierf","full_name":"Schlierf, Michael"},{"id":"48864","full_name":"Keller, Adrian","orcid":"0000-0001-7139-3110","first_name":"Adrian","last_name":"Keller"},{"full_name":"Krainer, Georg","last_name":"Krainer","first_name":"Georg"}],"date_updated":"2022-01-06T06:55:38Z","publication_status":"published","intvolume":"        11","page":"16270-16276","_id":"22653","language":[{"iso":"eng"}],"doi":"10.1039/c9nr04460d","user_id":"48864","volume":11,"publication":"Nanoscale","citation":{"chicago":"Ramakrishnan, Saminathan, Leonard Schärfen, Kristin Hunold, Sebastian Fricke, Guido Grundmeier, Michael Schlierf, Adrian Keller, and Georg Krainer. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” <i>Nanoscale</i> 11 (2019): 16270–76. <a href=\"https://doi.org/10.1039/c9nr04460d\">https://doi.org/10.1039/c9nr04460d</a>.","short":"S. Ramakrishnan, L. Schärfen, K. Hunold, S. Fricke, G. Grundmeier, M. Schlierf, A. Keller, G. Krainer, Nanoscale 11 (2019) 16270–16276.","apa":"Ramakrishnan, S., Schärfen, L., Hunold, K., Fricke, S., Grundmeier, G., Schlierf, M., … Krainer, G. (2019). Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. <i>Nanoscale</i>, <i>11</i>, 16270–16276. <a href=\"https://doi.org/10.1039/c9nr04460d\">https://doi.org/10.1039/c9nr04460d</a>","ieee":"S. Ramakrishnan <i>et al.</i>, “Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation,” <i>Nanoscale</i>, vol. 11, pp. 16270–16276, 2019.","ama":"Ramakrishnan S, Schärfen L, Hunold K, et al. Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. <i>Nanoscale</i>. 2019;11:16270-16276. doi:<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>","bibtex":"@article{Ramakrishnan_Schärfen_Hunold_Fricke_Grundmeier_Schlierf_Keller_Krainer_2019, title={Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation}, volume={11}, DOI={<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>}, journal={Nanoscale}, author={Ramakrishnan, Saminathan and Schärfen, Leonard and Hunold, Kristin and Fricke, Sebastian and Grundmeier, Guido and Schlierf, Michael and Keller, Adrian and Krainer, Georg}, year={2019}, pages={16270–16276} }","mla":"Ramakrishnan, Saminathan, et al. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” <i>Nanoscale</i>, vol. 11, 2019, pp. 16270–76, doi:<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>."},"abstract":[{"text":"<p>Merging of bridging staples with adjacent oligonucleotide sequences leads to a moderate increase of DNA origami stability, while enzymatic ligation after assembly yields a reinforced nanostructure with superior stability at up to 37 °C and in the presence of 6 M urea.</p>","lang":"eng"}],"date_created":"2021-07-08T12:10:44Z","type":"journal_article","department":[{"_id":"302"}]},{"publication":"Molecules","citation":{"bibtex":"@article{Kielar_Xin_Xu_Zhu_Gorin_Grundmeier_Möser_Smith_Keller_2019, title={Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability}, volume={24}, DOI={<a href=\"https://doi.org/10.3390/molecules24142577\">10.3390/molecules24142577</a>}, journal={Molecules}, author={Kielar, Charlotte and Xin, Yang and Xu, Xiaodan and Zhu, Siqi and Gorin, Nelli and Grundmeier, Guido and Möser, Christin and Smith, David M. and Keller, Adrian}, year={2019}, pages={2577} }","short":"C. Kielar, Y. Xin, X. Xu, S. Zhu, N. Gorin, G. Grundmeier, C. Möser, D.M. Smith, A. Keller, Molecules 24 (2019) 2577.","ama":"Kielar C, Xin Y, Xu X, et al. Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability. <i>Molecules</i>. 2019;24:2577. doi:<a href=\"https://doi.org/10.3390/molecules24142577\">10.3390/molecules24142577</a>","chicago":"Kielar, Charlotte, Yang Xin, Xiaodan Xu, Siqi Zhu, Nelli Gorin, Guido Grundmeier, Christin Möser, David M. Smith, and Adrian Keller. “Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability.” <i>Molecules</i> 24 (2019): 2577. <a href=\"https://doi.org/10.3390/molecules24142577\">https://doi.org/10.3390/molecules24142577</a>.","ieee":"C. Kielar <i>et al.</i>, “Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability,” <i>Molecules</i>, vol. 24, p. 2577, 2019.","mla":"Kielar, Charlotte, et al. “Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability.” <i>Molecules</i>, vol. 24, 2019, p. 2577, doi:<a href=\"https://doi.org/10.3390/molecules24142577\">10.3390/molecules24142577</a>.","apa":"Kielar, C., Xin, Y., Xu, X., Zhu, S., Gorin, N., Grundmeier, G., … Keller, A. (2019). Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability. <i>Molecules</i>, <i>24</i>, 2577. <a href=\"https://doi.org/10.3390/molecules24142577\">https://doi.org/10.3390/molecules24142577</a>"},"abstract":[{"text":"<jats:p>DNA origami nanostructures are widely employed in various areas of fundamental and applied research. Due to the tremendous success of the DNA origami technique in the academic field, considerable efforts currently aim at the translation of this technology from a laboratory setting to real-world applications, such as nanoelectronics, drug delivery, and biosensing. While many of these real-world applications rely on an intact DNA origami shape, they often also subject the DNA origami nanostructures to rather harsh and potentially damaging environmental and processing conditions. Furthermore, in the context of DNA origami mass production, the long-term storage of DNA origami nanostructures or their pre-assembled components also becomes an issue of high relevance, especially regarding the possible negative effects on DNA origami structural integrity. Thus, we investigated the effect of staple age on the self-assembly and stability of DNA origami nanostructures using atomic force microscopy. Different harsh processing conditions were simulated by applying different sample preparation protocols. Our results show that staple solutions may be stored at −20 °C for several years without impeding DNA origami self-assembly. Depending on DNA origami shape and superstructure, however, staple age may have negative effects on DNA origami stability under harsh treatment conditions. Mass spectrometry analysis of the aged staple mixtures revealed no signs of staple fragmentation. We, therefore, attribute the increased DNA origami sensitivity toward environmental conditions to an accumulation of damaged nucleobases, which undergo weaker base-pairing interactions and thus lead to reduced duplex stability.</jats:p>","lang":"eng"}],"date_created":"2021-07-08T12:12:53Z","type":"journal_article","department":[{"_id":"302"}],"year":"2019","status":"public","title":"Effect of Staple Age on DNA Origami Nanostructure Assembly and Stability","publication_identifier":{"issn":["1420-3049"]},"author":[{"full_name":"Kielar, Charlotte","first_name":"Charlotte","last_name":"Kielar"},{"first_name":"Yang","last_name":"Xin","full_name":"Xin, Yang"},{"last_name":"Xu","first_name":"Xiaodan","full_name":"Xu, Xiaodan"},{"last_name":"Zhu","first_name":"Siqi","full_name":"Zhu, Siqi"},{"full_name":"Gorin, Nelli","first_name":"Nelli","last_name":"Gorin"},{"full_name":"Grundmeier, Guido","first_name":"Guido","last_name":"Grundmeier","id":"194"},{"full_name":"Möser, Christin","first_name":"Christin","last_name":"Möser"},{"full_name":"Smith, David M.","first_name":"David M.","last_name":"Smith"},{"id":"48864","full_name":"Keller, Adrian","last_name":"Keller","first_name":"Adrian","orcid":"0000-0001-7139-3110"}],"publication_status":"published","date_updated":"2022-01-06T06:55:38Z","intvolume":"        24","page":"2577","_id":"22654","language":[{"iso":"eng"}],"user_id":"48864","doi":"10.3390/molecules24142577","volume":24},{"citation":{"ieee":"S. Ramakrishnan, B. Shen, M. Kostiainen, G. Grundmeier, A. Keller, and V. Linko, “Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy.,” <i>ChemBioChem</i>, vol. 20, no. 22, pp. 2818–2823, 2019.","apa":"Ramakrishnan, S., Shen, B., Kostiainen, M., Grundmeier, G., Keller, A., &#38; Linko, V. (2019). Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy. <i>ChemBioChem</i>, <i>20</i>(22), 2818–2823. <a href=\"https://doi.org/10.1002/cbic.201900369\">https://doi.org/10.1002/cbic.201900369</a>","mla":"Ramakrishnan, S., et al. “Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy.” <i>ChemBioChem</i>, vol. 20, no. 22, 2019, pp. 2818–23, doi:<a href=\"https://doi.org/10.1002/cbic.201900369\">10.1002/cbic.201900369</a>.","bibtex":"@article{Ramakrishnan_Shen_Kostiainen_Grundmeier_Keller_Linko_2019, title={Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy.}, volume={20}, DOI={<a href=\"https://doi.org/10.1002/cbic.201900369\">10.1002/cbic.201900369</a>}, number={22}, journal={ChemBioChem}, author={Ramakrishnan, S and Shen, B and Kostiainen, MA and Grundmeier, Guido and Keller, Adrian and Linko, V}, year={2019}, pages={2818–2823} }","chicago":"Ramakrishnan, S, B Shen, MA Kostiainen, Guido Grundmeier, Adrian Keller, and V Linko. “Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy.” <i>ChemBioChem</i> 20, no. 22 (2019): 2818–23. <a href=\"https://doi.org/10.1002/cbic.201900369\">https://doi.org/10.1002/cbic.201900369</a>.","short":"S. Ramakrishnan, B. Shen, M. Kostiainen, G. Grundmeier, A. Keller, V. Linko, ChemBioChem 20 (2019) 2818–2823.","ama":"Ramakrishnan S, Shen B, Kostiainen M, Grundmeier G, Keller A, Linko V. Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy. <i>ChemBioChem</i>. 2019;20(22):2818-2823. doi:<a href=\"https://doi.org/10.1002/cbic.201900369\">10.1002/cbic.201900369</a>"},"external_id":{"pmid":["31163091"]},"status":"public","volume":20,"user_id":"48864","_id":"22655","page":"2818-2823","publication":"ChemBioChem","issue":"22","department":[{"_id":"302"}],"type":"journal_article","date_created":"2021-07-08T12:14:23Z","intvolume":"        20","date_updated":"2022-01-06T06:55:38Z","publication_identifier":{"issn":["1439-4227","1439-7633"]},"author":[{"last_name":"Ramakrishnan","first_name":"S","full_name":"Ramakrishnan, S"},{"last_name":"Shen","first_name":"B","full_name":"Shen, B"},{"first_name":"MA","last_name":"Kostiainen","full_name":"Kostiainen, MA"},{"full_name":"Grundmeier, Guido","last_name":"Grundmeier","first_name":"Guido","id":"194"},{"first_name":"Adrian","last_name":"Keller","orcid":"0000-0001-7139-3110","full_name":"Keller, Adrian","id":"48864"},{"full_name":"Linko, V","last_name":"Linko","first_name":"V"}],"title":"Real-Time Observation of Superstructure-Dependent DNA Origami Digestion by DNase I Using High-Speed Atomic Force Microscopy.","year":"2019","doi":"10.1002/cbic.201900369","pmid":"1","language":[{"iso":"eng"}]}]