--- _id: '60180' author: - first_name: RM full_name: Kranz, RM last_name: Kranz - first_name: C full_name: Kettler, C last_name: Kettler - first_name: C full_name: Anand, C last_name: Anand - first_name: C full_name: Koeder, C last_name: Koeder - first_name: S full_name: Husain, S last_name: Husain - first_name: N full_name: Schoch, N last_name: Schoch - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: H full_name: Englert, H last_name: Englert citation: ama: 'Kranz R, Kettler C, Anand C, et al. Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutr Health. 2025;31(1):175-186.' apa: 'Kranz, R., Kettler, C., Anand, C., Koeder, C., Husain, S., Schoch, N., Buyken, A., & Englert, H. (2025). Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutr Health, 31(1), 175–186.' bibtex: '@article{Kranz_Kettler_Anand_Koeder_Husain_Schoch_Buyken_Englert_2025, title={Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2).}, volume={31}, number={1}, journal={Nutr Health}, author={Kranz, RM and Kettler, C and Anand, C and Koeder, C and Husain, S and Schoch, N and Buyken, Anette and Englert, H}, year={2025}, pages={175–186} }' chicago: 'Kranz, RM, C Kettler, C Anand, C Koeder, S Husain, N Schoch, Anette Buyken, and H Englert. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutr Health 31, no. 1 (2025): 175–86.' ieee: 'R. Kranz et al., “Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2).,” Nutr Health, vol. 31, no. 1, pp. 175–186, 2025.' mla: 'Kranz, RM, et al. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutr Health, vol. 31, no. 1, 2025, pp. 175–86.' short: R. Kranz, C. Kettler, C. Anand, C. Koeder, S. Husain, N. Schoch, A. Buyken, H. Englert, Nutr Health 31 (2025) 175–186. date_created: 2025-06-11T08:46:42Z date_updated: 2025-06-11T08:47:39Z department: - _id: '22' external_id: pmid: - '36938591' intvolume: ' 31' issue: '1' language: - iso: eng page: 175-186 pmid: '1' publication: Nutr Health publication_identifier: issn: - 0260-1060 status: public title: 'Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2).' type: journal_article user_id: '92491' volume: 31 year: '2025' ... --- _id: '45810' abstract: - lang: eng text: ' Background: Establishing a healthy lifestyle has a great potential to reduce the prevalence of non-communicable diseases (NCDs) and their risk factors. NCDs contribute immensely to the economic costs of the health care system arising from therapy, medication use, and productivity loss. Aim: The aim of this study was to evaluate the effect of the Healthy Lifestyle Community Program (cohort 2; HLCP-2) on medication use and consequently on medication costs for selected NCDs (diabetes, hypertension, and dyslipidemia). Methods: Data stem from a 24-month non-randomised, controlled intervention trial aiming to improve risk factors for NCDs. Participants completed questionnaires at six measurement time points assessing medication use, from which costs were calculated. The following medication groups were included in the analysis as NCD medication: glucose-lowering medications (GLM), antihypertensive drugs (AHD) and lipid-lowering drugs (LLD). Statistical tests for inter- and intra-group comparison and multiple regression analysis were performed. Results: In total, 118 participants (intervention group [IG]: n = 79; control group [CG]: n = 39) were considered. Compared to baseline medication use decreased slightly in the IG and increased in the CG. Costs for NCD medication were significantly lower in the IG than in the CG after 6 ( p = 0.004), 12 ( p = 0.040), 18 ( p = 0.003) and 24 months ( p = 0.008). After multiple regression analysis and adjusting for confounders, change of costs differed significantly between the groups in all final models. Conclusion: The HLCP-2 was able to moderately prevent an increase of medication use and thus reduce costs for medication to treat NCDs with the greatest impact on AHD. Trial registration German Clinical Trials Register DRKS ( www.drks.de ; reference: DRKS00018775). ' article_number: '026010602311646' author: - first_name: Ragna-Marie full_name: Kranz, Ragna-Marie last_name: Kranz - first_name: Carmen full_name: Kettler, Carmen last_name: Kettler - first_name: Corinna full_name: Anand, Corinna last_name: Anand - first_name: Christian full_name: Koeder, Christian last_name: Koeder - first_name: Sarah full_name: Husain, Sarah last_name: Husain - first_name: Nora full_name: Schoch, Nora last_name: Schoch - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Heike full_name: Englert, Heike last_name: Englert citation: ama: 'Kranz R-M, Kettler C, Anand C, et al. Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutrition and Health. Published online 2023. doi:10.1177/02601060231164665' apa: 'Kranz, R.-M., Kettler, C., Anand, C., Koeder, C., Husain, S., Schoch, N., Buyken, A., & Englert, H. (2023). Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutrition and Health, Article 026010602311646. https://doi.org/10.1177/02601060231164665' bibtex: '@article{Kranz_Kettler_Anand_Koeder_Husain_Schoch_Buyken_Englert_2023, title={Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2)}, DOI={10.1177/02601060231164665}, number={026010602311646}, journal={Nutrition and Health}, publisher={SAGE Publications}, author={Kranz, Ragna-Marie and Kettler, Carmen and Anand, Corinna and Koeder, Christian and Husain, Sarah and Schoch, Nora and Buyken, Anette and Englert, Heike}, year={2023} }' chicago: 'Kranz, Ragna-Marie, Carmen Kettler, Corinna Anand, Christian Koeder, Sarah Husain, Nora Schoch, Anette Buyken, and Heike Englert. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutrition and Health, 2023. https://doi.org/10.1177/02601060231164665.' ieee: 'R.-M. Kranz et al., “Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2),” Nutrition and Health, Art. no. 026010602311646, 2023, doi: 10.1177/02601060231164665.' mla: 'Kranz, Ragna-Marie, et al. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutrition and Health, 026010602311646, SAGE Publications, 2023, doi:10.1177/02601060231164665.' short: R.-M. Kranz, C. Kettler, C. Anand, C. Koeder, S. Husain, N. Schoch, A. Buyken, H. Englert, Nutrition and Health (2023). date_created: 2023-06-28T09:29:18Z date_updated: 2023-06-28T09:29:52Z department: - _id: '22' doi: 10.1177/02601060231164665 keyword: - Nutrition and Dietetics - General Medicine - Medicine (miscellaneous) language: - iso: eng publication: Nutrition and Health publication_identifier: issn: - 0260-1060 - 2047-945X publication_status: published publisher: SAGE Publications status: public title: 'Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2)' type: journal_article user_id: '92491' year: '2023' ... --- _id: '62901' abstract: - lang: eng text: "\r\n Background:\r\n Establishing a healthy lifestyle has a great potential to reduce the prevalence of non-communicable diseases (NCDs) and their risk factors. NCDs contribute immensely to the economic costs of the health care system arising from therapy, medication use, and productivity loss.\r\n Aim:\r\n The aim of this study was to evaluate the effect of the Healthy Lifestyle Community Program (cohort 2; HLCP-2) on medication use and consequently on medication costs for selected NCDs (diabetes, hypertension, and dyslipidemia).\r\n Methods:\r\n \ Data stem from a 24-month non-randomised, controlled intervention trial aiming to improve risk factors for NCDs. Participants completed questionnaires at six measurement time points assessing medication use, from which costs were calculated. The following medication groups were included in the analysis as NCD medication: glucose-lowering medications (GLM), antihypertensive drugs (AHD) and lipid-lowering drugs (LLD). Statistical tests for inter- and intra-group comparison and multiple regression analysis were performed.\r\n Results:\r\n \ In total, 118 participants (intervention group [IG]:\r\n n\r\n \  = 79; control group [CG]:\r\n n\r\n \  = 39) were considered. Compared to baseline medication use decreased slightly in the IG and increased in the CG. Costs for NCD medication were significantly lower in the IG than in the CG after 6 (\r\n p\r\n \  = 0.004), 12 (\r\n p\r\n  = 0.040), 18 (\r\n p\r\n  = 0.003) and 24 months (\r\n p\r\n  = 0.008). After multiple regression analysis and adjusting for confounders, change of costs differed significantly between the groups in all final models.\r\n Conclusion:\r\n \ The HLCP-2 was able to moderately prevent an increase of medication use and thus reduce costs for medication to treat NCDs with the greatest impact on AHD.\r\n \r\n \r\n Trial registration\r\n \r\n German Clinical Trials Register DRKS (\r\n www.drks.de\r\n \ ; reference: DRKS00018775).\r\n \r\n " author: - first_name: Ragna-Marie full_name: Kranz, Ragna-Marie last_name: Kranz - first_name: Carmen full_name: Kettler, Carmen last_name: Kettler - first_name: Corinna full_name: Anand, Corinna last_name: Anand - first_name: Christian full_name: Koeder, Christian last_name: Koeder - first_name: Sarah full_name: Husain, Sarah last_name: Husain - first_name: Nora full_name: Schoch, Nora last_name: Schoch - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Heike full_name: Englert, Heike last_name: Englert citation: ama: 'Kranz R-M, Kettler C, Anand C, et al. Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutrition and Health. 2023;31(1):175-186. doi:10.1177/02601060231164665' apa: 'Kranz, R.-M., Kettler, C., Anand, C., Koeder, C., Husain, S., Schoch, N., Buyken, A., & Englert, H. (2023). Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2). Nutrition and Health, 31(1), 175–186. https://doi.org/10.1177/02601060231164665' bibtex: '@article{Kranz_Kettler_Anand_Koeder_Husain_Schoch_Buyken_Englert_2023, title={Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2)}, volume={31}, DOI={10.1177/02601060231164665}, number={1}, journal={Nutrition and Health}, publisher={SAGE Publications}, author={Kranz, Ragna-Marie and Kettler, Carmen and Anand, Corinna and Koeder, Christian and Husain, Sarah and Schoch, Nora and Buyken, Anette and Englert, Heike}, year={2023}, pages={175–186} }' chicago: 'Kranz, Ragna-Marie, Carmen Kettler, Corinna Anand, Christian Koeder, Sarah Husain, Nora Schoch, Anette Buyken, and Heike Englert. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutrition and Health 31, no. 1 (2023): 175–86. https://doi.org/10.1177/02601060231164665.' ieee: 'R.-M. Kranz et al., “Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2),” Nutrition and Health, vol. 31, no. 1, pp. 175–186, 2023, doi: 10.1177/02601060231164665.' mla: 'Kranz, Ragna-Marie, et al. “Effect of a Controlled Lifestyle Intervention on Medication Use and Costs: The Healthy Lifestyle Community Program (Cohort 2).” Nutrition and Health, vol. 31, no. 1, SAGE Publications, 2023, pp. 175–86, doi:10.1177/02601060231164665.' short: R.-M. Kranz, C. Kettler, C. Anand, C. Koeder, S. Husain, N. Schoch, A. Buyken, H. Englert, Nutrition and Health 31 (2023) 175–186. date_created: 2025-12-04T14:34:41Z date_updated: 2025-12-04T14:35:11Z doi: 10.1177/02601060231164665 intvolume: ' 31' issue: '1' language: - iso: eng page: 175-186 publication: Nutrition and Health publication_identifier: issn: - 0260-1060 - 2047-945X publication_status: published publisher: SAGE Publications status: public title: 'Effect of a controlled lifestyle intervention on medication use and costs: The Healthy Lifestyle Community Program (cohort 2)' type: journal_article user_id: '92491' volume: 31 year: '2023' ...