---
_id: '60176'
abstract:
- lang: eng
  text: '<jats:title>Abstract</jats:title><jats:sec><jats:title>Aim</jats:title><jats:p>To
    investigate the associations of the Dietary Approaches to Stop Hypertension (DASH)
    score with subcutaneous (SAT) and visceral (VAT) adipose tissue volume and hepatic
    lipid content (HLC) in people with diabetes and to examine whether changes in
    the DASH diet were associated with changes in these outcomes.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In
    total, 335 participants with recent‐onset type 1 diabetes (T1D) and type 2 diabetes
    (T2D) from the German Diabetes Study were included in the cross‐sectional analysis,
    and 111 participants in the analysis of changes during the 5‐year follow‐up. Associations
    between the DASH score and VAT, SAT and HLC and their changes were investigated
    using multivariable linear regression models by diabetes type. The proportion
    mediated by changes in potential mediators was determined using mediation analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>A
    higher baseline DASH score was associated with lower HLC, especially in people
    with T2D (per 5 points: −1.5% [−2.7%; −0.3%]). Over 5 years, a 5‐point increase
    in the DASH score was associated with decreased VAT in people with T2D (−514 [−800;
    −228] cm<jats:sup>3</jats:sup>). Similar, but imprecise, associations were observed
    for VAT changes in people with T1D (−403 [−861; 55] cm<jats:sup>3</jats:sup>)
    and for HLC in people with T2D (−1.3% [−2.8%; 0.3%]). Body mass index and waist
    circumference changes explained 8%‐48% of the associations between DASH and VAT
    changes in both groups. In people with T2D, adipose tissue insulin resistance
    index (Adipo‐IR) changes explained 47% of the association between DASH and HLC
    changes.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>A
    shift to a DASH‐like diet was associated with favourable VAT and HLC changes,
    which were partly explained by changes in anthropometric measures and Adipo‐IR.</jats:p></jats:sec>'
author:
- first_name: Edyta
  full_name: Schaefer, Edyta
  last_name: Schaefer
- first_name: Alexander
  full_name: Lang, Alexander
  last_name: Lang
- first_name: Yuliya
  full_name: Kupriyanova, Yuliya
  last_name: Kupriyanova
- first_name: Kálmán B.
  full_name: Bódis, Kálmán B.
  last_name: Bódis
- first_name: Katharina S.
  full_name: Weber, Katharina S.
  last_name: Weber
- first_name: Anette
  full_name: Buyken, Anette
  id: '65985'
  last_name: Buyken
- first_name: Janett
  full_name: Barbaresko, Janett
  last_name: Barbaresko
- first_name: Theresa
  full_name: Kössler, Theresa
  last_name: Kössler
- first_name: Sabine
  full_name: Kahl, Sabine
  last_name: Kahl
- first_name: Oana‐Patricia
  full_name: Zaharia, Oana‐Patricia
  last_name: Zaharia
- first_name: Julia
  full_name: Szendroedi, Julia
  last_name: Szendroedi
- first_name: Christian
  full_name: Herder, Christian
  last_name: Herder
- first_name: Vera B.
  full_name: Schrauwen‐Hinderling, Vera B.
  last_name: Schrauwen‐Hinderling
- first_name: Robert
  full_name: Wagner, Robert
  last_name: Wagner
- first_name: Oliver
  full_name: Kuss, Oliver
  last_name: Kuss
- first_name: Michael
  full_name: Roden, Michael
  last_name: Roden
- first_name: Sabrina
  full_name: Schlesinger, Sabrina
  last_name: Schlesinger
citation:
  ama: Schaefer E, Lang A, Kupriyanova Y, et al. Adherence to the Dietary Approaches
    to Stop Hypertension (DASH) diet is associated with lower visceral and hepatic
    lipid content in recent‐onset type 1 diabetes and type 2 diabetes. <i>Diabetes,
    Obesity and Metabolism</i>. 2024;26(10):4281-4292. doi:<a href="https://doi.org/10.1111/dom.15772">10.1111/dom.15772</a>
  apa: Schaefer, E., Lang, A., Kupriyanova, Y., Bódis, K. B., Weber, K. S., Buyken,
    A., Barbaresko, J., Kössler, T., Kahl, S., Zaharia, O., Szendroedi, J., Herder,
    C., Schrauwen‐Hinderling, V. B., Wagner, R., Kuss, O., Roden, M., &#38; Schlesinger,
    S. (2024). Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet
    is associated with lower visceral and hepatic lipid content in recent‐onset type
    1 diabetes and type 2 diabetes. <i>Diabetes, Obesity and Metabolism</i>, <i>26</i>(10),
    4281–4292. <a href="https://doi.org/10.1111/dom.15772">https://doi.org/10.1111/dom.15772</a>
  bibtex: '@article{Schaefer_Lang_Kupriyanova_Bódis_Weber_Buyken_Barbaresko_Kössler_Kahl_Zaharia_et
    al._2024, title={Adherence to the Dietary Approaches to Stop Hypertension (DASH)
    diet is associated with lower visceral and hepatic lipid content in recent‐onset
    type 1 diabetes and type 2 diabetes}, volume={26}, DOI={<a href="https://doi.org/10.1111/dom.15772">10.1111/dom.15772</a>},
    number={10}, journal={Diabetes, Obesity and Metabolism}, publisher={Wiley}, author={Schaefer,
    Edyta and Lang, Alexander and Kupriyanova, Yuliya and Bódis, Kálmán B. and Weber,
    Katharina S. and Buyken, Anette and Barbaresko, Janett and Kössler, Theresa and
    Kahl, Sabine and Zaharia, Oana‐Patricia and et al.}, year={2024}, pages={4281–4292}
    }'
  chicago: 'Schaefer, Edyta, Alexander Lang, Yuliya Kupriyanova, Kálmán B. Bódis,
    Katharina S. Weber, Anette Buyken, Janett Barbaresko, et al. “Adherence to the
    Dietary Approaches to Stop Hypertension (DASH) Diet Is Associated with Lower Visceral
    and Hepatic Lipid Content in Recent‐onset Type 1 Diabetes and Type 2 Diabetes.”
    <i>Diabetes, Obesity and Metabolism</i> 26, no. 10 (2024): 4281–92. <a href="https://doi.org/10.1111/dom.15772">https://doi.org/10.1111/dom.15772</a>.'
  ieee: 'E. Schaefer <i>et al.</i>, “Adherence to the Dietary Approaches to Stop Hypertension
    (DASH) diet is associated with lower visceral and hepatic lipid content in recent‐onset
    type 1 diabetes and type 2 diabetes,” <i>Diabetes, Obesity and Metabolism</i>,
    vol. 26, no. 10, pp. 4281–4292, 2024, doi: <a href="https://doi.org/10.1111/dom.15772">10.1111/dom.15772</a>.'
  mla: Schaefer, Edyta, et al. “Adherence to the Dietary Approaches to Stop Hypertension
    (DASH) Diet Is Associated with Lower Visceral and Hepatic Lipid Content in Recent‐onset
    Type 1 Diabetes and Type 2 Diabetes.” <i>Diabetes, Obesity and Metabolism</i>,
    vol. 26, no. 10, Wiley, 2024, pp. 4281–92, doi:<a href="https://doi.org/10.1111/dom.15772">10.1111/dom.15772</a>.
  short: E. Schaefer, A. Lang, Y. Kupriyanova, K.B. Bódis, K.S. Weber, A. Buyken,
    J. Barbaresko, T. Kössler, S. Kahl, O. Zaharia, J. Szendroedi, C. Herder, V.B.
    Schrauwen‐Hinderling, R. Wagner, O. Kuss, M. Roden, S. Schlesinger, Diabetes,
    Obesity and Metabolism 26 (2024) 4281–4292.
date_created: 2025-06-11T08:39:22Z
date_updated: 2025-06-11T08:42:19Z
department:
- _id: '22'
doi: 10.1111/dom.15772
intvolume: '        26'
issue: '10'
language:
- iso: eng
page: 4281-4292
publication: Diabetes, Obesity and Metabolism
publication_identifier:
  issn:
  - 1462-8902
  - 1463-1326
publication_status: published
publisher: Wiley
status: public
title: Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated
  with lower visceral and hepatic lipid content in recent‐onset type 1 diabetes and
  type 2 diabetes
type: journal_article
user_id: '92491'
volume: 26
year: '2024'
...