---
_id: '63240'
abstract:
- lang: eng
  text: <jats:p>An electrochemical quartz crystal microbalance is described, which
    achieves a time resolution down to 100 μs. Accumulation and averaging over a few
    hours bring the noise down to about 30 mHz. The application examples are pH-driven
    viscosity changes in albumin solutions. The pH was switched with the electrode
    potential. The characteristic response time is in the millisecond range. The focus
    is on experimental aspects as well as advantages and limitations of the technique.</jats:p>
article_number: '021004'
author:
- first_name: Alexander
  full_name: Gödde, Alexander
  last_name: Gödde
- first_name: Christian
  full_name: Leppin, Christian
  id: '117722'
  last_name: Leppin
- first_name: Frederick S.
  full_name: Meyer, Frederick S.
  last_name: Meyer
- first_name: Arne
  full_name: Langhoff, Arne
  last_name: Langhoff
- first_name: Josef
  full_name: Hartl, Josef
  last_name: Hartl
- first_name: Patrick
  full_name: Garidel, Patrick
  last_name: Garidel
- first_name: Diethelm
  full_name: Johannsmann, Diethelm
  last_name: Johannsmann
citation:
  ama: Gödde A, Leppin C, Meyer FS, et al. Fast <i>p</i>H-mediated changes of the
    viscosity of protein solutions studied with a voltage-modulated quartz crystal
    microbalance. <i>Biointerphases</i>. 2020;15(2). doi:<a href="https://doi.org/10.1116/1.5140619">10.1116/1.5140619</a>
  apa: Gödde, A., Leppin, C., Meyer, F. S., Langhoff, A., Hartl, J., Garidel, P.,
    &#38; Johannsmann, D. (2020). Fast <i>p</i>H-mediated changes of the viscosity
    of protein solutions studied with a voltage-modulated quartz crystal microbalance.
    <i>Biointerphases</i>, <i>15</i>(2), Article 021004. <a href="https://doi.org/10.1116/1.5140619">https://doi.org/10.1116/1.5140619</a>
  bibtex: '@article{Gödde_Leppin_Meyer_Langhoff_Hartl_Garidel_Johannsmann_2020, title={Fast
    <i>p</i>H-mediated changes of the viscosity of protein solutions studied with
    a voltage-modulated quartz crystal microbalance}, volume={15}, DOI={<a href="https://doi.org/10.1116/1.5140619">10.1116/1.5140619</a>},
    number={2021004}, journal={Biointerphases}, publisher={American Vacuum Society},
    author={Gödde, Alexander and Leppin, Christian and Meyer, Frederick S. and Langhoff,
    Arne and Hartl, Josef and Garidel, Patrick and Johannsmann, Diethelm}, year={2020}
    }'
  chicago: Gödde, Alexander, Christian Leppin, Frederick S. Meyer, Arne Langhoff,
    Josef Hartl, Patrick Garidel, and Diethelm Johannsmann. “Fast <i>p</i>H-Mediated
    Changes of the Viscosity of Protein Solutions Studied with a Voltage-Modulated
    Quartz Crystal Microbalance.” <i>Biointerphases</i> 15, no. 2 (2020). <a href="https://doi.org/10.1116/1.5140619">https://doi.org/10.1116/1.5140619</a>.
  ieee: 'A. Gödde <i>et al.</i>, “Fast <i>p</i>H-mediated changes of the viscosity
    of protein solutions studied with a voltage-modulated quartz crystal microbalance,”
    <i>Biointerphases</i>, vol. 15, no. 2, Art. no. 021004, 2020, doi: <a href="https://doi.org/10.1116/1.5140619">10.1116/1.5140619</a>.'
  mla: Gödde, Alexander, et al. “Fast <i>p</i>H-Mediated Changes of the Viscosity
    of Protein Solutions Studied with a Voltage-Modulated Quartz Crystal Microbalance.”
    <i>Biointerphases</i>, vol. 15, no. 2, 021004, American Vacuum Society, 2020,
    doi:<a href="https://doi.org/10.1116/1.5140619">10.1116/1.5140619</a>.
  short: A. Gödde, C. Leppin, F.S. Meyer, A. Langhoff, J. Hartl, P. Garidel, D. Johannsmann,
    Biointerphases 15 (2020).
date_created: 2025-12-18T17:31:15Z
date_updated: 2025-12-18T17:35:30Z
doi: 10.1116/1.5140619
extern: '1'
intvolume: '        15'
issue: '2'
language:
- iso: eng
publication: Biointerphases
publication_identifier:
  issn:
  - 1934-8630
  - 1559-4106
publication_status: published
publisher: American Vacuum Society
quality_controlled: '1'
status: public
title: Fast <i>p</i>H-mediated changes of the viscosity of protein solutions studied
  with a voltage-modulated quartz crystal microbalance
type: journal_article
user_id: '117722'
volume: 15
year: '2020'
...