---
_id: '61335'
abstract:
- lang: eng
  text: <jats:p>Amidines are a ubiquitous class of bioactive compounds found in a
    wide variety of natural products; thus, efficient strategies for their preparation
    are in great demand. Herein, a novel protocol is reported for the synthesis of
    amidines based on P<jats:sup>III</jats:sup>/P<jats:sup>V</jats:sup>O redox catalysis.
    This two‐step, one‐pot approach involves the activation of amides via P<jats:sup>III</jats:sup>/P<jats:sup>V</jats:sup>O
    catalyzed in situ formation of imidoyl chloride intermediates which are directly
    converted upon reaction with amines into the corresponding amidines. Instead of
    traditionally used toxic and corrosive chloride sources, hexachloroacetone (HCA)
    is successfully employed as a halide source. The reaction proceeds with low catalyst
    loading (2 mol%) in BuOAc as the solvent. Under the optimized conditions, 20 amidines
    are prepared in yields up to 99%. A feasible mechanism is proposed based on experimental
    results. The synthetic potential of this method is evaluated in the preparation
    of the tyrosine kinase inhibitor (TKI) Erlotinib.</jats:p>
article_number: '202500394'
author:
- first_name: Viktorija
  full_name: Medvaric, Viktorija
  id: '92677'
  last_name: Medvaric
- first_name: Jan
  full_name: Paradies, Jan
  id: '53339'
  last_name: Paradies
  orcid: 0000-0002-3698-668X
- first_name: Thomas
  full_name: Werner, Thomas
  id: '89271'
  last_name: Werner
  orcid: 0000-0001-9025-3244
citation:
  ama: Medvaric V, Paradies J, Werner T. Synthesis of Amidines Via P(III)/P(V)=O Redox
    Catalyzed In Situ Formation of Imidoyl Chlorides From Amides. <i>Advanced Synthesis
    and Catalysis</i>. Published online 2025. doi:<a href="https://doi.org/10.1002/adsc.70059">10.1002/adsc.70059</a>
  apa: Medvaric, V., Paradies, J., &#38; Werner, T. (2025). Synthesis of Amidines
    Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From
    Amides. <i>Advanced Synthesis and Catalysis</i>, Article 202500394. <a href="https://doi.org/10.1002/adsc.70059">https://doi.org/10.1002/adsc.70059</a>
  bibtex: '@article{Medvaric_Paradies_Werner_2025, title={Synthesis of Amidines Via
    P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides},
    DOI={<a href="https://doi.org/10.1002/adsc.70059">10.1002/adsc.70059</a>}, number={202500394},
    journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Medvaric,
    Viktorija and Paradies, Jan and Werner, Thomas}, year={2025} }'
  chicago: Medvaric, Viktorija, Jan Paradies, and Thomas Werner. “Synthesis of Amidines
    Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From
    Amides.” <i>Advanced Synthesis and Catalysis</i>, 2025. <a href="https://doi.org/10.1002/adsc.70059">https://doi.org/10.1002/adsc.70059</a>.
  ieee: 'V. Medvaric, J. Paradies, and T. Werner, “Synthesis of Amidines Via P(III)/P(V)=O
    Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides,” <i>Advanced
    Synthesis and Catalysis</i>, Art. no. 202500394, 2025, doi: <a href="https://doi.org/10.1002/adsc.70059">10.1002/adsc.70059</a>.'
  mla: Medvaric, Viktorija, et al. “Synthesis of Amidines Via P(III)/P(V)=O Redox
    Catalyzed In Situ Formation of Imidoyl Chlorides From Amides.” <i>Advanced Synthesis
    and Catalysis</i>, 202500394, Wiley, 2025, doi:<a href="https://doi.org/10.1002/adsc.70059">10.1002/adsc.70059</a>.
  short: V. Medvaric, J. Paradies, T. Werner, Advanced Synthesis and Catalysis (2025).
date_created: 2025-09-17T15:16:49Z
date_updated: 2025-11-10T08:44:04Z
department:
- _id: '2'
- _id: '389'
doi: 10.1002/adsc.70059
keyword:
- T2
- T
- CSSD
language:
- iso: eng
publication: Advanced Synthesis and Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of
  Imidoyl Chlorides From Amides
type: journal_article
user_id: '89271'
year: '2025'
...
---
_id: '55371'
abstract:
- lang: eng
  text: <jats:title>Abstract</jats:title><jats:p>The activation of C(<jats:italic>sp</jats:italic><jats:sup>3</jats:sup>)−F
    bonds by the commercially available catalyst B(C<jats:sub>6</jats:sub>F<jats:sub>5</jats:sub>)<jats:sub>3</jats:sub>
    is reported and applied in reactions with arenes, allylic, vinylic and acetylenic
    silanes, and olefins to achieve a variety of C−C bond formations (45 examples).</jats:p>
author:
- first_name: Axel
  full_name: Hoppe, Axel
  last_name: Hoppe
- first_name: Arne J.
  full_name: Stepen, Arne J.
  last_name: Stepen
- first_name: Laura
  full_name: Köring, Laura
  last_name: Köring
- first_name: Jan
  full_name: Paradies, Jan
  id: '53339'
  last_name: Paradies
  orcid: 0000-0002-3698-668X
citation:
  ama: Hoppe A, Stepen AJ, Köring L, Paradies J. Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>.
    2024;366(13):2933-2938. doi:<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>
  apa: Hoppe, A., Stepen, A. J., Köring, L., &#38; Paradies, J. (2024). Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    <i>366</i>(13), 2933–2938. <a href="https://doi.org/10.1002/adsc.202400511">https://doi.org/10.1002/adsc.202400511</a>
  bibtex: '@article{Hoppe_Stepen_Köring_Paradies_2024, title={Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds}, volume={366}, DOI={<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>},
    number={13}, journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley},
    author={Hoppe, Axel and Stepen, Arne J. and Köring, Laura and Paradies, Jan},
    year={2024}, pages={2933–2938} }'
  chicago: 'Hoppe, Axel, Arne J. Stepen, Laura Köring, and Jan Paradies. “Tris(Pentafluorophenyl)Borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i>
    366, no. 13 (2024): 2933–38. <a href="https://doi.org/10.1002/adsc.202400511">https://doi.org/10.1002/adsc.202400511</a>.'
  ieee: 'A. Hoppe, A. J. Stepen, L. Köring, and J. Paradies, “Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds,” <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    vol. 366, no. 13, pp. 2933–2938, 2024, doi: <a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>.'
  mla: Hoppe, Axel, et al. “Tris(Pentafluorophenyl)Borane‐Catalyzed Functionalization
    of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 366,
    no. 13, Wiley, 2024, pp. 2933–38, doi:<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>.
  short: A. Hoppe, A.J. Stepen, L. Köring, J. Paradies, Advanced Synthesis &#38;amp;
    Catalysis 366 (2024) 2933–2938.
date_created: 2024-07-24T09:16:15Z
date_updated: 2024-07-24T09:18:18Z
department:
- _id: '2'
- _id: '389'
doi: 10.1002/adsc.202400511
intvolume: '       366'
issue: '13'
language:
- iso: eng
page: 2933-2938
publication: Advanced Synthesis &amp; Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds
type: journal_article
user_id: '53339'
volume: 366
year: '2024'
...
---
_id: '59616'
abstract:
- lang: eng
  text: <jats:title>Abstract</jats:title><jats:p>The activation of C(<jats:italic>sp</jats:italic><jats:sup>3</jats:sup>)−F
    bonds by the commercially available catalyst B(C<jats:sub>6</jats:sub>F<jats:sub>5</jats:sub>)<jats:sub>3</jats:sub>
    is reported and applied in reactions with arenes, allylic, vinylic and acetylenic
    silanes, and olefins to achieve a variety of C−C bond formations (45 examples).</jats:p>
author:
- first_name: Axel
  full_name: Hoppe, Axel
  id: '62844'
  last_name: Hoppe
- first_name: Arne J.
  full_name: Stepen, Arne J.
  last_name: Stepen
- first_name: Laura
  full_name: Köring, Laura
  last_name: Köring
- first_name: Jan
  full_name: Paradies, Jan
  id: '53339'
  last_name: Paradies
  orcid: 0000-0002-3698-668X
citation:
  ama: Hoppe A, Stepen AJ, Köring L, Paradies J. Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>.
    2024;366(13):2933-2938. doi:<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>
  apa: Hoppe, A., Stepen, A. J., Köring, L., &#38; Paradies, J. (2024). Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds. <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    <i>366</i>(13), 2933–2938. <a href="https://doi.org/10.1002/adsc.202400511">https://doi.org/10.1002/adsc.202400511</a>
  bibtex: '@article{Hoppe_Stepen_Köring_Paradies_2024, title={Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds}, volume={366}, DOI={<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>},
    number={13}, journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley},
    author={Hoppe, Axel and Stepen, Arne J. and Köring, Laura and Paradies, Jan},
    year={2024}, pages={2933–2938} }'
  chicago: 'Hoppe, Axel, Arne J. Stepen, Laura Köring, and Jan Paradies. “Tris(Pentafluorophenyl)Borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i>
    366, no. 13 (2024): 2933–38. <a href="https://doi.org/10.1002/adsc.202400511">https://doi.org/10.1002/adsc.202400511</a>.'
  ieee: 'A. Hoppe, A. J. Stepen, L. Köring, and J. Paradies, “Tris(pentafluorophenyl)borane‐Catalyzed
    Functionalization of Benzylic C−F Bonds,” <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    vol. 366, no. 13, pp. 2933–2938, 2024, doi: <a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>.'
  mla: Hoppe, Axel, et al. “Tris(Pentafluorophenyl)Borane‐Catalyzed Functionalization
    of Benzylic C−F Bonds.” <i>Advanced Synthesis &#38;amp; Catalysis</i>, vol. 366,
    no. 13, Wiley, 2024, pp. 2933–38, doi:<a href="https://doi.org/10.1002/adsc.202400511">10.1002/adsc.202400511</a>.
  short: A. Hoppe, A.J. Stepen, L. Köring, J. Paradies, Advanced Synthesis &#38;amp;
    Catalysis 366 (2024) 2933–2938.
date_created: 2025-04-22T05:59:08Z
date_updated: 2025-04-22T06:11:59Z
department:
- _id: '389'
doi: 10.1002/adsc.202400511
intvolume: '       366'
issue: '13'
keyword:
- fluoride
- bond activation
- borane
- Lewis acid
- C-C bond formation
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202400511
oa: '1'
page: 2933-2938
publication: Advanced Synthesis &amp; Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Tris(pentafluorophenyl)borane‐Catalyzed Functionalization of Benzylic C−F Bonds
type: journal_article
user_id: '62844'
volume: 366
year: '2024'
...
---
_id: '35692'
author:
- first_name: Benedikt
  full_name: Sieland, Benedikt
  last_name: Sieland
- first_name: Axel
  full_name: Hoppe, Axel
  last_name: Hoppe
- first_name: Arne J.
  full_name: Stepen, Arne J.
  last_name: Stepen
- first_name: Jan
  full_name: Paradies, Jan
  id: '53339'
  last_name: Paradies
  orcid: 0000-0002-3698-668X
citation:
  ama: 'Sieland B, Hoppe A, Stepen AJ, Paradies J. Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis. <i>Advanced Synthesis
    &#38;amp; Catalysis</i>. 2022;364(18):3143-3148. doi:<a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>'
  apa: 'Sieland, B., Hoppe, A., Stepen, A. J., &#38; Paradies, J. (2022). Frustrated
    Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.
    <i>Advanced Synthesis &#38;amp; Catalysis</i>, <i>364</i>(18), 3143–3148. <a href="https://doi.org/10.1002/adsc.202200525">https://doi.org/10.1002/adsc.202200525</a>'
  bibtex: '@article{Sieland_Hoppe_Stepen_Paradies_2022, title={Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis}, volume={364}, DOI={<a
    href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>}, number={18},
    journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley}, author={Sieland,
    Benedikt and Hoppe, Axel and Stepen, Arne J. and Paradies, Jan}, year={2022},
    pages={3143–3148} }'
  chicago: 'Sieland, Benedikt, Axel Hoppe, Arne J. Stepen, and Jan Paradies. “Frustrated
    Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.”
    <i>Advanced Synthesis &#38;amp; Catalysis</i> 364, no. 18 (2022): 3143–48. <a
    href="https://doi.org/10.1002/adsc.202200525">https://doi.org/10.1002/adsc.202200525</a>.'
  ieee: 'B. Sieland, A. Hoppe, A. J. Stepen, and J. Paradies, “Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis,” <i>Advanced Synthesis
    &#38;amp; Catalysis</i>, vol. 364, no. 18, pp. 3143–3148, 2022, doi: <a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>.'
  mla: 'Sieland, Benedikt, et al. “Frustrated Lewis Pair‐Catalyzed Hydroboration of
    Nitriles: FLP Versus Borenium Catalysis.” <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    vol. 364, no. 18, Wiley, 2022, pp. 3143–48, doi:<a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>.'
  short: B. Sieland, A. Hoppe, A.J. Stepen, J. Paradies, Advanced Synthesis &#38;amp;
    Catalysis 364 (2022) 3143–3148.
date_created: 2023-01-10T08:58:42Z
date_updated: 2023-01-23T12:52:02Z
doi: 10.1002/adsc.202200525
intvolume: '       364'
issue: '18'
keyword:
- General Chemistry
language:
- iso: eng
page: 3143-3148
publication: Advanced Synthesis &amp; Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: 'Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium
  Catalysis'
type: journal_article
user_id: '53339'
volume: 364
year: '2022'
...
---
_id: '59619'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title><jats:p>A frustrated Lewis pair‐catalyzed
    hydroboration of aromatic and aliphatic nitriles was developed. The catalyst provides
    the primary amines in high yields of 77–99% with catalyst loading as low as 2 mol%.
    The reaction displays high functional group tolerance towards esters, amides,
    nitro groups and aliphatic halides. The addition of the diborylated amines to
    ethyl 3‐phenylpropiolate proceeds with Z‐selectivity with d.r. of &gt;99:1 in
    77–90% yield over two steps. The reaction mechanism was investigated by control
    and computational experiments.</jats:p><jats:p><jats:boxed-text content-type=\"graphic\"
    position=\"anchor\"><jats:graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\"
    mimetype=\"image/png\" position=\"anchor\" specific-use=\"enlarged-web-image\"
    xlink:href=\"graphic/adsc202200525-toc-0001-m.png\"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text>\r\n</jats:p>"
author:
- first_name: Benedikt
  full_name: Sieland, Benedikt
  last_name: Sieland
- first_name: Axel
  full_name: Hoppe, Axel
  id: '62844'
  last_name: Hoppe
- first_name: Arne J.
  full_name: Stepen, Arne J.
  last_name: Stepen
- first_name: Jan
  full_name: Paradies, Jan
  id: '53339'
  last_name: Paradies
  orcid: 0000-0002-3698-668X
citation:
  ama: 'Sieland B, Hoppe A, Stepen AJ, Paradies J. Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis. <i>Advanced Synthesis
    &#38;amp; Catalysis</i>. 2022;364(18):3143-3148. doi:<a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>'
  apa: 'Sieland, B., Hoppe, A., Stepen, A. J., &#38; Paradies, J. (2022). Frustrated
    Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.
    <i>Advanced Synthesis &#38;amp; Catalysis</i>, <i>364</i>(18), 3143–3148. <a href="https://doi.org/10.1002/adsc.202200525">https://doi.org/10.1002/adsc.202200525</a>'
  bibtex: '@article{Sieland_Hoppe_Stepen_Paradies_2022, title={Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis}, volume={364}, DOI={<a
    href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>}, number={18},
    journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley}, author={Sieland,
    Benedikt and Hoppe, Axel and Stepen, Arne J. and Paradies, Jan}, year={2022},
    pages={3143–3148} }'
  chicago: 'Sieland, Benedikt, Axel Hoppe, Arne J. Stepen, and Jan Paradies. “Frustrated
    Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium Catalysis.”
    <i>Advanced Synthesis &#38;amp; Catalysis</i> 364, no. 18 (2022): 3143–48. <a
    href="https://doi.org/10.1002/adsc.202200525">https://doi.org/10.1002/adsc.202200525</a>.'
  ieee: 'B. Sieland, A. Hoppe, A. J. Stepen, and J. Paradies, “Frustrated Lewis Pair‐Catalyzed
    Hydroboration of Nitriles: FLP Versus Borenium Catalysis,” <i>Advanced Synthesis
    &#38;amp; Catalysis</i>, vol. 364, no. 18, pp. 3143–3148, 2022, doi: <a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>.'
  mla: 'Sieland, Benedikt, et al. “Frustrated Lewis Pair‐Catalyzed Hydroboration of
    Nitriles: FLP Versus Borenium Catalysis.” <i>Advanced Synthesis &#38;amp; Catalysis</i>,
    vol. 364, no. 18, Wiley, 2022, pp. 3143–48, doi:<a href="https://doi.org/10.1002/adsc.202200525">10.1002/adsc.202200525</a>.'
  short: B. Sieland, A. Hoppe, A.J. Stepen, J. Paradies, Advanced Synthesis &#38;amp;
    Catalysis 364 (2022) 3143–3148.
date_created: 2025-04-22T06:01:56Z
date_updated: 2025-04-22T06:12:05Z
department:
- _id: '389'
doi: 10.1002/adsc.202200525
intvolume: '       364'
issue: '18'
keyword:
- hydroboration
- nitrile
- amine
- frustrated Lewis pair
- density functional theory
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202200525
oa: '1'
page: 3143-3148
publication: Advanced Synthesis &amp; Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: 'Frustrated Lewis Pair‐Catalyzed Hydroboration of Nitriles: FLP Versus Borenium
  Catalysis'
type: journal_article
user_id: '62844'
volume: 364
year: '2022'
...
---
_id: '37948'
author:
- first_name: Xin
  full_name: Liu, Xin
  last_name: Liu
- first_name: Thomas
  full_name: Werner, Thomas
  id: '89271'
  last_name: Werner
  orcid: https://orcid.org/0000-0001-9025-3244
citation:
  ama: Liu X, Werner T. Selective Construction of C−C and C=C Bonds by Manganese Catalyzed
    Coupling of Alcohols with Phosphorus Ylides. <i>Advanced Synthesis and Catalysis</i>.
    2021;363(4):1096-1104. doi:<a href="https://doi.org/10.1002/adsc.202001209">10.1002/adsc.202001209</a>
  apa: Liu, X., &#38; Werner, T. (2021). Selective Construction of C−C and C=C Bonds
    by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides. <i>Advanced
    Synthesis and Catalysis</i>, <i>363</i>(4), 1096–1104. <a href="https://doi.org/10.1002/adsc.202001209">https://doi.org/10.1002/adsc.202001209</a>
  bibtex: '@article{Liu_Werner_2021, title={Selective Construction of C−C and C=C
    Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides}, volume={363},
    DOI={<a href="https://doi.org/10.1002/adsc.202001209">10.1002/adsc.202001209</a>},
    number={4}, journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Liu,
    Xin and Werner, Thomas}, year={2021}, pages={1096–1104} }'
  chicago: 'Liu, Xin, and Thomas Werner. “Selective Construction of C−C and C=C Bonds
    by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides.” <i>Advanced
    Synthesis and Catalysis</i> 363, no. 4 (2021): 1096–1104. <a href="https://doi.org/10.1002/adsc.202001209">https://doi.org/10.1002/adsc.202001209</a>.'
  ieee: 'X. Liu and T. Werner, “Selective Construction of C−C and C=C Bonds by Manganese
    Catalyzed Coupling of Alcohols with Phosphorus Ylides,” <i>Advanced Synthesis
    and Catalysis</i>, vol. 363, no. 4, pp. 1096–1104, 2021, doi: <a href="https://doi.org/10.1002/adsc.202001209">10.1002/adsc.202001209</a>.'
  mla: Liu, Xin, and Thomas Werner. “Selective Construction of C−C and C=C Bonds by
    Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides.” <i>Advanced
    Synthesis and Catalysis</i>, vol. 363, no. 4, Wiley, 2021, pp. 1096–104, doi:<a
    href="https://doi.org/10.1002/adsc.202001209">10.1002/adsc.202001209</a>.
  short: X. Liu, T. Werner, Advanced Synthesis and Catalysis 363 (2021) 1096–1104.
date_created: 2023-01-22T20:30:29Z
date_updated: 2025-11-10T08:48:47Z
department:
- _id: '35'
- _id: '2'
- _id: '657'
doi: 10.1002/adsc.202001209
extern: '1'
intvolume: '       363'
issue: '4'
keyword:
- T1
- T3
- CSSD
language:
- iso: eng
page: 1096-1104
publication: Advanced Synthesis and Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling
  of Alcohols with Phosphorus Ylides
type: journal_article
user_id: '89271'
volume: 363
year: '2021'
...
---
_id: '38009'
author:
- first_name: Thomas
  full_name: Werner, Thomas
  id: '89271'
  last_name: Werner
  orcid: 0000-0001-9025-3244
citation:
  ama: Werner T. Phosphonium Salt Organocatalysis. <i>Advanced Synthesis &#38;amp;
    Catalysis</i>. 2009;351(10):1469-1481. doi:<a href="https://doi.org/10.1002/adsc.200900211">10.1002/adsc.200900211</a>
  apa: Werner, T. (2009). Phosphonium Salt Organocatalysis. <i>Advanced Synthesis
    &#38;amp; Catalysis</i>, <i>351</i>(10), 1469–1481. <a href="https://doi.org/10.1002/adsc.200900211">https://doi.org/10.1002/adsc.200900211</a>
  bibtex: '@article{Werner_2009, title={Phosphonium Salt Organocatalysis}, volume={351},
    DOI={<a href="https://doi.org/10.1002/adsc.200900211">10.1002/adsc.200900211</a>},
    number={10}, journal={Advanced Synthesis &#38;amp; Catalysis}, publisher={Wiley},
    author={Werner, Thomas}, year={2009}, pages={1469–1481} }'
  chicago: 'Werner, Thomas. “Phosphonium Salt Organocatalysis.” <i>Advanced Synthesis
    &#38;amp; Catalysis</i> 351, no. 10 (2009): 1469–81. <a href="https://doi.org/10.1002/adsc.200900211">https://doi.org/10.1002/adsc.200900211</a>.'
  ieee: 'T. Werner, “Phosphonium Salt Organocatalysis,” <i>Advanced Synthesis &#38;amp;
    Catalysis</i>, vol. 351, no. 10, pp. 1469–1481, 2009, doi: <a href="https://doi.org/10.1002/adsc.200900211">10.1002/adsc.200900211</a>.'
  mla: Werner, Thomas. “Phosphonium Salt Organocatalysis.” <i>Advanced Synthesis &#38;amp;
    Catalysis</i>, vol. 351, no. 10, Wiley, 2009, pp. 1469–81, doi:<a href="https://doi.org/10.1002/adsc.200900211">10.1002/adsc.200900211</a>.
  short: T. Werner, Advanced Synthesis &#38;amp; Catalysis 351 (2009) 1469–1481.
date_created: 2023-01-22T21:12:23Z
date_updated: 2025-11-10T09:41:55Z
department:
- _id: '35'
- _id: '2'
- _id: '657'
doi: 10.1002/adsc.200900211
extern: '1'
intvolume: '       351'
issue: '10'
keyword:
- T2
language:
- iso: eng
page: 1469-1481
publication: Advanced Synthesis &amp; Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: Phosphonium Salt Organocatalysis
type: journal_article
user_id: '89271'
volume: 351
year: '2009'
...
---
_id: '38017'
author:
- first_name: Jens
  full_name: Christoffers, Jens
  last_name: Christoffers
- first_name: Angelika
  full_name: Baro, Angelika
  last_name: Baro
- first_name: Thomas
  full_name: Werner, Thomas
  id: '89271'
  last_name: Werner
  orcid: 0000-0001-9025-3244
citation:
  ama: Christoffers J, Baro A, Werner T. α-Hydroxylation ofβ-Dicarbonyl Compounds.
    <i>Advanced Synthesis and Catalysis</i>. 2004;346(23):143-151. doi:<a href="https://doi.org/10.1002/adsc.200303140">10.1002/adsc.200303140</a>
  apa: Christoffers, J., Baro, A., &#38; Werner, T. (2004). α-Hydroxylation ofβ-Dicarbonyl
    Compounds. <i>Advanced Synthesis and Catalysis</i>, <i>346</i>(23), 143–151. <a
    href="https://doi.org/10.1002/adsc.200303140">https://doi.org/10.1002/adsc.200303140</a>
  bibtex: '@article{Christoffers_Baro_Werner_2004, title={α-Hydroxylation ofβ-Dicarbonyl
    Compounds}, volume={346}, DOI={<a href="https://doi.org/10.1002/adsc.200303140">10.1002/adsc.200303140</a>},
    number={23}, journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Christoffers,
    Jens and Baro, Angelika and Werner, Thomas}, year={2004}, pages={143–151} }'
  chicago: 'Christoffers, Jens, Angelika Baro, and Thomas Werner. “α-Hydroxylation
    Ofβ-Dicarbonyl Compounds.” <i>Advanced Synthesis and Catalysis</i> 346, no. 23
    (2004): 143–51. <a href="https://doi.org/10.1002/adsc.200303140">https://doi.org/10.1002/adsc.200303140</a>.'
  ieee: 'J. Christoffers, A. Baro, and T. Werner, “α-Hydroxylation ofβ-Dicarbonyl
    Compounds,” <i>Advanced Synthesis and Catalysis</i>, vol. 346, no. 23, pp. 143–151,
    2004, doi: <a href="https://doi.org/10.1002/adsc.200303140">10.1002/adsc.200303140</a>.'
  mla: Christoffers, Jens, et al. “α-Hydroxylation Ofβ-Dicarbonyl Compounds.” <i>Advanced
    Synthesis and Catalysis</i>, vol. 346, no. 23, Wiley, 2004, pp. 143–51, doi:<a
    href="https://doi.org/10.1002/adsc.200303140">10.1002/adsc.200303140</a>.
  short: J. Christoffers, A. Baro, T. Werner, Advanced Synthesis and Catalysis 346
    (2004) 143–151.
date_created: 2023-01-22T21:15:14Z
date_updated: 2025-11-10T09:46:02Z
department:
- _id: '35'
- _id: '2'
- _id: '657'
doi: 10.1002/adsc.200303140
extern: '1'
intvolume: '       346'
issue: '23'
keyword:
- General Chemistry
language:
- iso: eng
page: 143-151
publication: Advanced Synthesis and Catalysis
publication_identifier:
  issn:
  - 1615-4150
  - 1615-4169
publication_status: published
publisher: Wiley
status: public
title: α-Hydroxylation ofβ-Dicarbonyl Compounds
type: journal_article
user_id: '89271'
volume: 346
year: '2004'
...