---
_id: '26014'
abstract:
- lang: eng
  text: <jats:p>Whereas initial findings have already identified cortical patterns
    accompanying proprioceptive deficiencies in patients after anterior cruciate ligament
    reconstruction (ACLR), little is known about compensatory sensorimotor mechanisms
    for re-establishing postural control. Therefore, the aim of the present study
    was to explore leg dependent patterns of cortical contributions to postural control
    in patients 6 weeks following ACLR. A total of 12 patients after ACLR (25.1 ±
    3.2 years, 178.1 ± 9.7 cm, 77.5 ± 14.4 kg) and another 12 gender, age, and activity
    matched healthy controls participated in this study. All subjects performed 10
    × 30 s. single leg stances on each leg, equipped with 64-channel mobile electroencephalography
    (EEG). Postural stability was quantified by area of sway and sway velocity. Estimations
    of the weighted phase lag index were conducted as a cortical measure of functional
    connectivity. The findings showed significant group × leg interactions for increased
    functional connectivity in the anterior cruciate ligament (ACL) injured leg, predominantly
    including fronto−parietal [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub>
    = 8.41, <jats:italic>p</jats:italic> ≤ 0.008, η<jats:sup>2</jats:sup> = 0.28],
    fronto−occipital [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 4.43,
    <jats:italic>p</jats:italic> ≤ 0.047, η<jats:sup>2</jats:sup> = 0.17], parieto−motor
    [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 10.30, <jats:italic>p</jats:italic>
    ≤ 0.004, η<jats:sup>2</jats:sup> = 0.32], occipito−motor [<jats:italic>F</jats:italic><jats:sub>(1,
    22)</jats:sub> = 5.21, <jats:italic>p</jats:italic> ≤ 0.032, η<jats:sup>2</jats:sup>
    = 0.19], and occipito−parietal [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub>
    = 4.60, <jats:italic>p</jats:italic> ≤ 0.043, η<jats:sup>2</jats:sup> = 0.17]
    intra−hemispherical connections in the contralateral hemisphere and occipito−motor
    [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 7.33, <jats:italic>p</jats:italic>
    ≤ 0.013, η<jats:sup>2</jats:sup> = 0.25] on the ipsilateral hemisphere to the
    injured leg. Higher functional connectivity in patients after ACLR, attained by
    increased emphasis of functional connections incorporating the somatosensory and
    visual areas, may serve as a compensatory mechanism to control postural stability
    of the injured leg in the early phase of rehabilitation. These preliminary results
    may help to develop new neurophysiological assessments for detecting functional
    deficiencies after ACLR in the future.</jats:p>
author:
- first_name: Tim
  full_name: Lehmann, Tim
  last_name: Lehmann
- first_name: Daniel
  full_name: Büchel, Daniel
  id: '41088'
  last_name: Büchel
- first_name: Caroline
  full_name: Mouton, Caroline
  last_name: Mouton
- first_name: Alli
  full_name: Gokeler, Alli
  last_name: Gokeler
- first_name: Romain
  full_name: Seil, Romain
  last_name: Seil
- first_name: Jochen
  full_name: Baumeister, Jochen
  id: '46'
  last_name: Baumeister
  orcid: 0000-0003-2683-5826
citation:
  ama: Lehmann T, Büchel D, Mouton C, Gokeler A, Seil R, Baumeister J. Functional
    Cortical Connectivity Related to Postural Control in Patients Six Weeks After
    Anterior Cruciate Ligament Reconstruction. <i>Frontiers in Human Neuroscience</i>.
    Published online 2021. doi:<a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>
  apa: Lehmann, T., Büchel, D., Mouton, C., Gokeler, A., Seil, R., &#38; Baumeister,
    J. (2021). Functional Cortical Connectivity Related to Postural Control in Patients
    Six Weeks After Anterior Cruciate Ligament Reconstruction. <i>Frontiers in Human
    Neuroscience</i>. <a href="https://doi.org/10.3389/fnhum.2021.655116">https://doi.org/10.3389/fnhum.2021.655116</a>
  bibtex: '@article{Lehmann_Büchel_Mouton_Gokeler_Seil_Baumeister_2021, title={Functional
    Cortical Connectivity Related to Postural Control in Patients Six Weeks After
    Anterior Cruciate Ligament Reconstruction}, DOI={<a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>},
    journal={Frontiers in Human Neuroscience}, author={Lehmann, Tim and Büchel, Daniel
    and Mouton, Caroline and Gokeler, Alli and Seil, Romain and Baumeister, Jochen},
    year={2021} }'
  chicago: Lehmann, Tim, Daniel Büchel, Caroline Mouton, Alli Gokeler, Romain Seil,
    and Jochen Baumeister. “Functional Cortical Connectivity Related to Postural Control
    in Patients Six Weeks After Anterior Cruciate Ligament Reconstruction.” <i>Frontiers
    in Human Neuroscience</i>, 2021. <a href="https://doi.org/10.3389/fnhum.2021.655116">https://doi.org/10.3389/fnhum.2021.655116</a>.
  ieee: 'T. Lehmann, D. Büchel, C. Mouton, A. Gokeler, R. Seil, and J. Baumeister,
    “Functional Cortical Connectivity Related to Postural Control in Patients Six
    Weeks After Anterior Cruciate Ligament Reconstruction,” <i>Frontiers in Human
    Neuroscience</i>, 2021, doi: <a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>.'
  mla: Lehmann, Tim, et al. “Functional Cortical Connectivity Related to Postural
    Control in Patients Six Weeks After Anterior Cruciate Ligament Reconstruction.”
    <i>Frontiers in Human Neuroscience</i>, 2021, doi:<a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>.
  short: T. Lehmann, D. Büchel, C. Mouton, A. Gokeler, R. Seil, J. Baumeister, Frontiers
    in Human Neuroscience (2021).
date_created: 2021-10-11T07:45:35Z
date_updated: 2022-01-06T06:57:15Z
department:
- _id: '172'
doi: 10.3389/fnhum.2021.655116
language:
- iso: eng
publication: Frontiers in Human Neuroscience
publication_identifier:
  issn:
  - 1662-5161
publication_status: published
status: public
title: Functional Cortical Connectivity Related to Postural Control in Patients Six
  Weeks After Anterior Cruciate Ligament Reconstruction
type: journal_article
user_id: '41088'
year: '2021'
...
---
_id: '32434'
abstract:
- lang: eng
  text: <jats:p>Whereas initial findings have already identified cortical patterns
    accompanying proprioceptive deficiencies in patients after anterior cruciate ligament
    reconstruction (ACLR), little is known about compensatory sensorimotor mechanisms
    for re-establishing postural control. Therefore, the aim of the present study
    was to explore leg dependent patterns of cortical contributions to postural control
    in patients 6 weeks following ACLR. A total of 12 patients after ACLR (25.1 ±
    3.2 years, 178.1 ± 9.7 cm, 77.5 ± 14.4 kg) and another 12 gender, age, and activity
    matched healthy controls participated in this study. All subjects performed 10
    × 30 s. single leg stances on each leg, equipped with 64-channel mobile electroencephalography
    (EEG). Postural stability was quantified by area of sway and sway velocity. Estimations
    of the weighted phase lag index were conducted as a cortical measure of functional
    connectivity. The findings showed significant group × leg interactions for increased
    functional connectivity in the anterior cruciate ligament (ACL) injured leg, predominantly
    including fronto−parietal [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub>
    = 8.41, <jats:italic>p</jats:italic> ≤ 0.008, η<jats:sup>2</jats:sup> = 0.28],
    fronto−occipital [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 4.43,
    <jats:italic>p</jats:italic> ≤ 0.047, η<jats:sup>2</jats:sup> = 0.17], parieto−motor
    [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 10.30, <jats:italic>p</jats:italic>
    ≤ 0.004, η<jats:sup>2</jats:sup> = 0.32], occipito−motor [<jats:italic>F</jats:italic><jats:sub>(1,
    22)</jats:sub> = 5.21, <jats:italic>p</jats:italic> ≤ 0.032, η<jats:sup>2</jats:sup>
    = 0.19], and occipito−parietal [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub>
    = 4.60, <jats:italic>p</jats:italic> ≤ 0.043, η<jats:sup>2</jats:sup> = 0.17]
    intra−hemispherical connections in the contralateral hemisphere and occipito−motor
    [<jats:italic>F</jats:italic><jats:sub>(1, 22)</jats:sub> = 7.33, <jats:italic>p</jats:italic>
    ≤ 0.013, η<jats:sup>2</jats:sup> = 0.25] on the ipsilateral hemisphere to the
    injured leg. Higher functional connectivity in patients after ACLR, attained by
    increased emphasis of functional connections incorporating the somatosensory and
    visual areas, may serve as a compensatory mechanism to control postural stability
    of the injured leg in the early phase of rehabilitation. These preliminary results
    may help to develop new neurophysiological assessments for detecting functional
    deficiencies after ACLR in the future.</jats:p>
author:
- first_name: Tim
  full_name: Lehmann, Tim
  id: '41584'
  last_name: Lehmann
- first_name: Daniel
  full_name: Büchel, Daniel
  id: '41088'
  last_name: Büchel
- first_name: Caroline
  full_name: Mouton, Caroline
  last_name: Mouton
- first_name: Alli
  full_name: Gokeler, Alli
  last_name: Gokeler
- first_name: Romain
  full_name: Seil, Romain
  last_name: Seil
- first_name: Jochen
  full_name: Baumeister, Jochen
  id: '46'
  last_name: Baumeister
  orcid: 0000-0003-2683-5826
citation:
  ama: Lehmann T, Büchel D, Mouton C, Gokeler A, Seil R, Baumeister J. Functional
    Cortical Connectivity Related to Postural Control in Patients Six Weeks After
    Anterior Cruciate Ligament Reconstruction. <i>Frontiers in Human Neuroscience</i>.
    2021;15. doi:<a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>
  apa: Lehmann, T., Büchel, D., Mouton, C., Gokeler, A., Seil, R., &#38; Baumeister,
    J. (2021). Functional Cortical Connectivity Related to Postural Control in Patients
    Six Weeks After Anterior Cruciate Ligament Reconstruction. <i>Frontiers in Human
    Neuroscience</i>, <i>15</i>. <a href="https://doi.org/10.3389/fnhum.2021.655116">https://doi.org/10.3389/fnhum.2021.655116</a>
  bibtex: '@article{Lehmann_Büchel_Mouton_Gokeler_Seil_Baumeister_2021, title={Functional
    Cortical Connectivity Related to Postural Control in Patients Six Weeks After
    Anterior Cruciate Ligament Reconstruction}, volume={15}, DOI={<a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>},
    journal={Frontiers in Human Neuroscience}, publisher={Frontiers Media SA}, author={Lehmann,
    Tim and Büchel, Daniel and Mouton, Caroline and Gokeler, Alli and Seil, Romain
    and Baumeister, Jochen}, year={2021} }'
  chicago: Lehmann, Tim, Daniel Büchel, Caroline Mouton, Alli Gokeler, Romain Seil,
    and Jochen Baumeister. “Functional Cortical Connectivity Related to Postural Control
    in Patients Six Weeks After Anterior Cruciate Ligament Reconstruction.” <i>Frontiers
    in Human Neuroscience</i> 15 (2021). <a href="https://doi.org/10.3389/fnhum.2021.655116">https://doi.org/10.3389/fnhum.2021.655116</a>.
  ieee: 'T. Lehmann, D. Büchel, C. Mouton, A. Gokeler, R. Seil, and J. Baumeister,
    “Functional Cortical Connectivity Related to Postural Control in Patients Six
    Weeks After Anterior Cruciate Ligament Reconstruction,” <i>Frontiers in Human
    Neuroscience</i>, vol. 15, 2021, doi: <a href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>.'
  mla: Lehmann, Tim, et al. “Functional Cortical Connectivity Related to Postural
    Control in Patients Six Weeks After Anterior Cruciate Ligament Reconstruction.”
    <i>Frontiers in Human Neuroscience</i>, vol. 15, Frontiers Media SA, 2021, doi:<a
    href="https://doi.org/10.3389/fnhum.2021.655116">10.3389/fnhum.2021.655116</a>.
  short: T. Lehmann, D. Büchel, C. Mouton, A. Gokeler, R. Seil, J. Baumeister, Frontiers
    in Human Neuroscience 15 (2021).
date_created: 2022-07-27T07:47:56Z
date_updated: 2023-03-13T15:20:11Z
department:
- _id: '17'
- _id: '172'
doi: 10.3389/fnhum.2021.655116
intvolume: '        15'
keyword:
- Behavioral Neuroscience
- Biological Psychiatry
- Psychiatry and Mental health
- Neurology
- Neuropsychology and Physiological Psychology
language:
- iso: eng
publication: Frontiers in Human Neuroscience
publication_identifier:
  issn:
  - 1662-5161
publication_status: published
publisher: Frontiers Media SA
status: public
title: Functional Cortical Connectivity Related to Postural Control in Patients Six
  Weeks After Anterior Cruciate Ligament Reconstruction
type: journal_article
user_id: '46'
volume: 15
year: '2021'
...