@article{54422,
  abstract     = {{<jats:title>Abstract</jats:title><jats:sec>
                <jats:title>Background</jats:title>
                <jats:p>The cereal fibre β-glucan reduces postprandial glycaemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute effect of a β-glucan-enriched oat bread on gastric emptying half-time (<jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub>), gastric emptying lag phase (<jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub>), and gastric emptying rate (GER), and the secretion of glucagon-like peptide-1 (GLP-1) as potential means to influence postprandial glycaemia.</jats:p>
              </jats:sec><jats:sec>
                <jats:title>Methods</jats:title>
                <jats:p>A randomised crossover trial was conducted in 22 healthy adults (age 24.6 ± 3.1 years, BMI 23.1 ± 2.7 kg/m<jats:sup>2</jats:sup>) receiving 25 g available carbohydrates from a β-glucan-enriched oat bread or a control whole-wheat bread at two non-consecutive days. <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub>, <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub>, and GER were determined based on ultrasound measures of the cross-sectional gastric antrum area in the fasting state and 15, 30, 45, 60, 90, and 120 min postprandially. Capillary glucose, serum insulin, and plasma GLP-1 concentrations were measured at the same time points.</jats:p>
              </jats:sec><jats:sec>
                <jats:title>Results</jats:title>
                <jats:p>A biphasic pattern of gastric emptying with a distinct <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> before the commencement of emptying was observed in most subjects for both bread types. While no differences in GER were evident (<jats:italic>p</jats:italic> = 0.562), consumption of the oat bread significantly increased <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub> by 18 min and <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> by 14 min compared with the whole-wheat bread (<jats:italic>p</jats:italic> = 0.005 and <jats:italic>p</jats:italic> = 0.010, respectively). In addition, the oat bread significantly reduced iAUC<jats:sub>2h</jats:sub> for glucose and insulin responses compared with the whole-wheat bread (<jats:italic>p</jats:italic> = 0.001 and <jats:italic>p</jats:italic> &lt; 0.001, respectively). There were no significant differences in GLP-1 response between the two breads (<jats:italic>p</jats:italic> = 0.892).</jats:p>
              </jats:sec><jats:sec>
                <jats:title>Conclusion</jats:title>
                <jats:p>The increased <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub> and <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> could offer a potential mechanism for the observed attenuation of postprandial glycaemia and insulinemia after consumption of the β-glucan-enriched oat bread compared with the whole-wheat bread.</jats:p>
                <jats:p><jats:italic>Trial registration</jats:italic>: The study is registered at clinicaltrails.gov (NCT04571866).</jats:p>
              </jats:sec>}},
  author       = {{Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}},
  issn         = {{1743-7075}},
  journal      = {{Nutrition &amp; Metabolism}},
  number       = {{1}},
  publisher    = {{Springer Science and Business Media LLC}},
  title        = {{{The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}}},
  doi          = {{10.1186/s12986-024-00789-w}},
  volume       = {{21}},
  year         = {{2024}},
}

@article{60178,
  author       = {{Revheim, I and Ballance, S and Standal, AF and Rieder, A and Dierkes, J and Buyken, Anette and Gilja, OH and Hausken, T and Rosendahl-Riise, H}},
  issn         = {{1743-7075}},
  journal      = {{Nutr Metab (Lond)}},
  number       = {{1}},
  pages        = {{101}},
  title        = {{{Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.}}},
  volume       = {{21}},
  year         = {{2024}},
}

@article{62902,
  author       = {{Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}},
  issn         = {{1743-7075}},
  journal      = {{Nutrition &amp; Metabolism}},
  number       = {{1}},
  publisher    = {{Springer Science and Business Media LLC}},
  title        = {{{Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}}},
  doi          = {{10.1186/s12986-024-00872-2}},
  volume       = {{21}},
  year         = {{2024}},
}