[{"_id":"54422","department":[{"_id":"22"}],"user_id":"92491","article_number":"13","language":[{"iso":"eng"}],"publication":"Nutrition &amp; Metabolism","type":"journal_article","abstract":[{"text":"<jats:title>Abstract</jats:title><jats:sec>\r\n                <jats:title>Background</jats:title>\r\n                <jats:p>The cereal fibre β-glucan reduces postprandial glycaemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute effect of a β-glucan-enriched oat bread on gastric emptying half-time (<jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub>), gastric emptying lag phase (<jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub>), and gastric emptying rate (GER), and the secretion of glucagon-like peptide-1 (GLP-1) as potential means to influence postprandial glycaemia.</jats:p>\r\n              </jats:sec><jats:sec>\r\n                <jats:title>Methods</jats:title>\r\n                <jats:p>A randomised crossover trial was conducted in 22 healthy adults (age 24.6 ± 3.1 years, BMI 23.1 ± 2.7 kg/m<jats:sup>2</jats:sup>) receiving 25 g available carbohydrates from a β-glucan-enriched oat bread or a control whole-wheat bread at two non-consecutive days. <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub>, <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub>, and GER were determined based on ultrasound measures of the cross-sectional gastric antrum area in the fasting state and 15, 30, 45, 60, 90, and 120 min postprandially. Capillary glucose, serum insulin, and plasma GLP-1 concentrations were measured at the same time points.</jats:p>\r\n              </jats:sec><jats:sec>\r\n                <jats:title>Results</jats:title>\r\n                <jats:p>A biphasic pattern of gastric emptying with a distinct <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> before the commencement of emptying was observed in most subjects for both bread types. While no differences in GER were evident (<jats:italic>p</jats:italic> = 0.562), consumption of the oat bread significantly increased <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub> by 18 min and <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> by 14 min compared with the whole-wheat bread (<jats:italic>p</jats:italic> = 0.005 and <jats:italic>p</jats:italic> = 0.010, respectively). In addition, the oat bread significantly reduced iAUC<jats:sub>2h</jats:sub> for glucose and insulin responses compared with the whole-wheat bread (<jats:italic>p</jats:italic> = 0.001 and <jats:italic>p</jats:italic> &lt; 0.001, respectively). There were no significant differences in GLP-1 response between the two breads (<jats:italic>p</jats:italic> = 0.892).</jats:p>\r\n              </jats:sec><jats:sec>\r\n                <jats:title>Conclusion</jats:title>\r\n                <jats:p>The increased <jats:italic>T</jats:italic><jats:sub><jats:italic>1/2</jats:italic></jats:sub> and <jats:italic>T</jats:italic><jats:sub><jats:italic>lag</jats:italic></jats:sub> could offer a potential mechanism for the observed attenuation of postprandial glycaemia and insulinemia after consumption of the β-glucan-enriched oat bread compared with the whole-wheat bread.</jats:p>\r\n                <jats:p><jats:italic>Trial registration</jats:italic>: The study is registered at clinicaltrails.gov (NCT04571866).</jats:p>\r\n              </jats:sec>","lang":"eng"}],"status":"public","publisher":"Springer Science and Business Media LLC","date_updated":"2024-05-23T06:41:09Z","volume":21,"date_created":"2024-05-23T06:40:49Z","author":[{"first_name":"Ingrid","last_name":"Revheim","full_name":"Revheim, Ingrid"},{"first_name":"Simon","last_name":"Ballance","full_name":"Ballance, Simon"},{"full_name":"Standal, Adelheid Fretland","last_name":"Standal","first_name":"Adelheid Fretland"},{"last_name":"Rieder","full_name":"Rieder, Anne","first_name":"Anne"},{"first_name":"Jutta","last_name":"Dierkes","full_name":"Dierkes, Jutta"},{"last_name":"Buyken","id":"65985","full_name":"Buyken, Anette","first_name":"Anette"},{"full_name":"Gilja, Odd Helge","last_name":"Gilja","first_name":"Odd Helge"},{"full_name":"Hausken, Trygve","last_name":"Hausken","first_name":"Trygve"},{"first_name":"Hanne","full_name":"Rosendahl-Riise, Hanne","last_name":"Rosendahl-Riise"}],"title":"The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults","doi":"10.1186/s12986-024-00789-w","publication_identifier":{"issn":["1743-7075"]},"publication_status":"published","issue":"1","year":"2024","intvolume":"        21","citation":{"ama":"Revheim I, Ballance S, Standal AF, et al. The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutrition &#38;amp; Metabolism</i>. 2024;21(1). doi:<a href=\"https://doi.org/10.1186/s12986-024-00789-w\">10.1186/s12986-024-00789-w</a>","ieee":"I. Revheim <i>et al.</i>, “The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults,” <i>Nutrition &#38;amp; Metabolism</i>, vol. 21, no. 1, Art. no. 13, 2024, doi: <a href=\"https://doi.org/10.1186/s12986-024-00789-w\">10.1186/s12986-024-00789-w</a>.","chicago":"Revheim, Ingrid, Simon Ballance, Adelheid Fretland Standal, Anne Rieder, Jutta Dierkes, Anette Buyken, Odd Helge Gilja, Trygve Hausken, and Hanne Rosendahl-Riise. “The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutrition &#38;amp; Metabolism</i> 21, no. 1 (2024). <a href=\"https://doi.org/10.1186/s12986-024-00789-w\">https://doi.org/10.1186/s12986-024-00789-w</a>.","apa":"Revheim, I., Ballance, S., Standal, A. F., Rieder, A., Dierkes, J., Buyken, A., Gilja, O. H., Hausken, T., &#38; Rosendahl-Riise, H. (2024). The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutrition &#38;amp; Metabolism</i>, <i>21</i>(1), Article 13. <a href=\"https://doi.org/10.1186/s12986-024-00789-w\">https://doi.org/10.1186/s12986-024-00789-w</a>","mla":"Revheim, Ingrid, et al. “The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutrition &#38;amp; Metabolism</i>, vol. 21, no. 1, 13, Springer Science and Business Media LLC, 2024, doi:<a href=\"https://doi.org/10.1186/s12986-024-00789-w\">10.1186/s12986-024-00789-w</a>.","short":"I. Revheim, S. Ballance, A.F. Standal, A. Rieder, J. Dierkes, A. Buyken, O.H. Gilja, T. Hausken, H. Rosendahl-Riise, Nutrition &#38;amp; Metabolism 21 (2024).","bibtex":"@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}, volume={21}, DOI={<a href=\"https://doi.org/10.1186/s12986-024-00789-w\">10.1186/s12986-024-00789-w</a>}, number={113}, journal={Nutrition &#38;amp; Metabolism}, publisher={Springer Science and Business Media LLC}, author={Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}, year={2024} }"}},{"title":"Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.","date_created":"2025-06-11T08:44:13Z","author":[{"last_name":"Revheim","full_name":"Revheim, I","first_name":"I"},{"full_name":"Ballance, S","last_name":"Ballance","first_name":"S"},{"full_name":"Standal, AF","last_name":"Standal","first_name":"AF"},{"first_name":"A","full_name":"Rieder, A","last_name":"Rieder"},{"last_name":"Dierkes","full_name":"Dierkes, J","first_name":"J"},{"first_name":"Anette","last_name":"Buyken","full_name":"Buyken, Anette","id":"65985"},{"first_name":"OH","full_name":"Gilja, OH","last_name":"Gilja"},{"last_name":"Hausken","full_name":"Hausken, T","first_name":"T"},{"first_name":"H","full_name":"Rosendahl-Riise, H","last_name":"Rosendahl-Riise"}],"volume":21,"date_updated":"2025-06-11T08:45:02Z","citation":{"ama":"Revheim I, Ballance S, Standal A, et al. Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutr Metab (Lond)</i>. 2024;21(1):101.","ieee":"I. Revheim <i>et al.</i>, “Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.,” <i>Nutr Metab (Lond)</i>, vol. 21, no. 1, p. 101, 2024.","chicago":"Revheim, I, S Ballance, AF Standal, A Rieder, J Dierkes, Anette Buyken, OH Gilja, T Hausken, and H Rosendahl-Riise. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutr Metab (Lond)</i> 21, no. 1 (2024): 101.","apa":"Revheim, I., Ballance, S., Standal, A., Rieder, A., Dierkes, J., Buyken, A., Gilja, O., Hausken, T., &#38; Rosendahl-Riise, H. (2024). Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutr Metab (Lond)</i>, <i>21</i>(1), 101.","short":"I. Revheim, S. Ballance, A. Standal, A. Rieder, J. Dierkes, A. Buyken, O. Gilja, T. Hausken, H. Rosendahl-Riise, Nutr Metab (Lond) 21 (2024) 101.","bibtex":"@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.}, volume={21}, number={1}, journal={Nutr Metab (Lond)}, author={Revheim, I and Ballance, S and Standal, AF and Rieder, A and Dierkes, J and Buyken, Anette and Gilja, OH and Hausken, T and Rosendahl-Riise, H}, year={2024}, pages={101} }","mla":"Revheim, I., et al. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutr Metab (Lond)</i>, vol. 21, no. 1, 2024, p. 101."},"page":"101","intvolume":"        21","year":"2024","issue":"1","publication_identifier":{"issn":["1743-7075"]},"pmid":"1","language":[{"iso":"eng"}],"user_id":"92491","external_id":{"pmid":["39633450"]},"_id":"60178","status":"public","type":"journal_article","publication":"Nutr Metab (Lond)"},{"_id":"62902","user_id":"92491","article_number":"101","language":[{"iso":"eng"}],"type":"journal_article","publication":"Nutrition &amp; Metabolism","status":"public","publisher":"Springer Science and Business Media LLC","date_updated":"2025-12-04T14:41:37Z","author":[{"first_name":"Ingrid","full_name":"Revheim, Ingrid","last_name":"Revheim"},{"last_name":"Ballance","full_name":"Ballance, Simon","first_name":"Simon"},{"full_name":"Standal, Adelheid Fretland","last_name":"Standal","first_name":"Adelheid Fretland"},{"first_name":"Anne","last_name":"Rieder","full_name":"Rieder, Anne"},{"last_name":"Dierkes","full_name":"Dierkes, Jutta","first_name":"Jutta"},{"last_name":"Buyken","id":"65985","full_name":"Buyken, Anette","first_name":"Anette"},{"first_name":"Odd Helge","last_name":"Gilja","full_name":"Gilja, Odd Helge"},{"full_name":"Hausken, Trygve","last_name":"Hausken","first_name":"Trygve"},{"full_name":"Rosendahl-Riise, Hanne","last_name":"Rosendahl-Riise","first_name":"Hanne"}],"date_created":"2025-12-04T14:41:20Z","volume":21,"title":"Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults","doi":"10.1186/s12986-024-00872-2","publication_status":"published","publication_identifier":{"issn":["1743-7075"]},"issue":"1","year":"2024","citation":{"mla":"Revheim, Ingrid, et al. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutrition &#38;amp; Metabolism</i>, vol. 21, no. 1, 101, Springer Science and Business Media LLC, 2024, doi:<a href=\"https://doi.org/10.1186/s12986-024-00872-2\">10.1186/s12986-024-00872-2</a>.","short":"I. Revheim, S. Ballance, A.F. Standal, A. Rieder, J. Dierkes, A. Buyken, O.H. Gilja, T. Hausken, H. Rosendahl-Riise, Nutrition &#38;amp; Metabolism 21 (2024).","bibtex":"@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}, volume={21}, DOI={<a href=\"https://doi.org/10.1186/s12986-024-00872-2\">10.1186/s12986-024-00872-2</a>}, number={1101}, journal={Nutrition &#38;amp; Metabolism}, publisher={Springer Science and Business Media LLC}, author={Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}, year={2024} }","apa":"Revheim, I., Ballance, S., Standal, A. F., Rieder, A., Dierkes, J., Buyken, A., Gilja, O. H., Hausken, T., &#38; Rosendahl-Riise, H. (2024). Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutrition &#38;amp; Metabolism</i>, <i>21</i>(1), Article 101. <a href=\"https://doi.org/10.1186/s12986-024-00872-2\">https://doi.org/10.1186/s12986-024-00872-2</a>","chicago":"Revheim, Ingrid, Simon Ballance, Adelheid Fretland Standal, Anne Rieder, Jutta Dierkes, Anette Buyken, Odd Helge Gilja, Trygve Hausken, and Hanne Rosendahl-Riise. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” <i>Nutrition &#38;amp; Metabolism</i> 21, no. 1 (2024). <a href=\"https://doi.org/10.1186/s12986-024-00872-2\">https://doi.org/10.1186/s12986-024-00872-2</a>.","ieee":"I. Revheim <i>et al.</i>, “Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults,” <i>Nutrition &#38;amp; Metabolism</i>, vol. 21, no. 1, Art. no. 101, 2024, doi: <a href=\"https://doi.org/10.1186/s12986-024-00872-2\">10.1186/s12986-024-00872-2</a>.","ama":"Revheim I, Ballance S, Standal AF, et al. Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. <i>Nutrition &#38;amp; Metabolism</i>. 2024;21(1). doi:<a href=\"https://doi.org/10.1186/s12986-024-00872-2\">10.1186/s12986-024-00872-2</a>"},"intvolume":"        21"}]