--- _id: '54422' abstract: - lang: eng text: "Abstract\r\n Background\r\n \ The cereal fibre β-glucan reduces postprandial glycaemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute effect of a β-glucan-enriched oat bread on gastric emptying half-time (T1/2), gastric emptying lag phase (Tlag), and gastric emptying rate (GER), and the secretion of glucagon-like peptide-1 (GLP-1) as potential means to influence postprandial glycaemia.\r\n \r\n \ Methods\r\n A randomised crossover trial was conducted in 22 healthy adults (age 24.6 ± 3.1 years, BMI 23.1 ± 2.7 kg/m2) receiving 25 g available carbohydrates from a β-glucan-enriched oat bread or a control whole-wheat bread at two non-consecutive days. T1/2, Tlag, and GER were determined based on ultrasound measures of the cross-sectional gastric antrum area in the fasting state and 15, 30, 45, 60, 90, and 120 min postprandially. Capillary glucose, serum insulin, and plasma GLP-1 concentrations were measured at the same time points.\r\n \r\n Results\r\n \ A biphasic pattern of gastric emptying with a distinct Tlag before the commencement of emptying was observed in most subjects for both bread types. While no differences in GER were evident (p = 0.562), consumption of the oat bread significantly increased T1/2 by 18 min and Tlag by 14 min compared with the whole-wheat bread (p = 0.005 and p = 0.010, respectively). In addition, the oat bread significantly reduced iAUC2h for glucose and insulin responses compared with the whole-wheat bread (p = 0.001 and p < 0.001, respectively). There were no significant differences in GLP-1 response between the two breads (p = 0.892).\r\n \ \r\n Conclusion\r\n \ The increased T1/2 and Tlag could offer a potential mechanism for the observed attenuation of postprandial glycaemia and insulinemia after consumption of the β-glucan-enriched oat bread compared with the whole-wheat bread.\r\n Trial registration: The study is registered at clinicaltrails.gov (NCT04571866).\r\n \ " article_number: '13' author: - first_name: Ingrid full_name: Revheim, Ingrid last_name: Revheim - first_name: Simon full_name: Ballance, Simon last_name: Ballance - first_name: Adelheid Fretland full_name: Standal, Adelheid Fretland last_name: Standal - first_name: Anne full_name: Rieder, Anne last_name: Rieder - first_name: Jutta full_name: Dierkes, Jutta last_name: Dierkes - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Odd Helge full_name: Gilja, Odd Helge last_name: Gilja - first_name: Trygve full_name: Hausken, Trygve last_name: Hausken - first_name: Hanne full_name: Rosendahl-Riise, Hanne last_name: Rosendahl-Riise citation: ama: 'Revheim I, Ballance S, Standal AF, et al. The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutrition &amp; Metabolism. 2024;21(1). doi:10.1186/s12986-024-00789-w' apa: 'Revheim, I., Ballance, S., Standal, A. F., Rieder, A., Dierkes, J., Buyken, A., Gilja, O. H., Hausken, T., & Rosendahl-Riise, H. (2024). The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutrition &amp; Metabolism, 21(1), Article 13. https://doi.org/10.1186/s12986-024-00789-w' bibtex: '@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}, volume={21}, DOI={10.1186/s12986-024-00789-w}, number={113}, journal={Nutrition &amp; Metabolism}, publisher={Springer Science and Business Media LLC}, author={Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}, year={2024} }' chicago: 'Revheim, Ingrid, Simon Ballance, Adelheid Fretland Standal, Anne Rieder, Jutta Dierkes, Anette Buyken, Odd Helge Gilja, Trygve Hausken, and Hanne Rosendahl-Riise. “The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutrition &amp; Metabolism 21, no. 1 (2024). https://doi.org/10.1186/s12986-024-00789-w.' ieee: 'I. Revheim et al., “The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults,” Nutrition &amp; Metabolism, vol. 21, no. 1, Art. no. 13, 2024, doi: 10.1186/s12986-024-00789-w.' mla: 'Revheim, Ingrid, et al. “The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutrition &amp; Metabolism, vol. 21, no. 1, 13, Springer Science and Business Media LLC, 2024, doi:10.1186/s12986-024-00789-w.' short: I. Revheim, S. Ballance, A.F. Standal, A. Rieder, J. Dierkes, A. Buyken, O.H. Gilja, T. Hausken, H. Rosendahl-Riise, Nutrition &amp; Metabolism 21 (2024). date_created: 2024-05-23T06:40:49Z date_updated: 2024-05-23T06:41:09Z department: - _id: '22' doi: 10.1186/s12986-024-00789-w intvolume: ' 21' issue: '1' language: - iso: eng publication: Nutrition & Metabolism publication_identifier: issn: - 1743-7075 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults' type: journal_article user_id: '92491' volume: 21 year: '2024' ... --- _id: '60178' author: - first_name: I full_name: Revheim, I last_name: Revheim - first_name: S full_name: Ballance, S last_name: Ballance - first_name: AF full_name: Standal, AF last_name: Standal - first_name: A full_name: Rieder, A last_name: Rieder - first_name: J full_name: Dierkes, J last_name: Dierkes - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: OH full_name: Gilja, OH last_name: Gilja - first_name: T full_name: Hausken, T last_name: Hausken - first_name: H full_name: Rosendahl-Riise, H last_name: Rosendahl-Riise citation: ama: 'Revheim I, Ballance S, Standal A, et al. Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutr Metab (Lond). 2024;21(1):101.' apa: 'Revheim, I., Ballance, S., Standal, A., Rieder, A., Dierkes, J., Buyken, A., Gilja, O., Hausken, T., & Rosendahl-Riise, H. (2024). Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutr Metab (Lond), 21(1), 101.' bibtex: '@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.}, volume={21}, number={1}, journal={Nutr Metab (Lond)}, author={Revheim, I and Ballance, S and Standal, AF and Rieder, A and Dierkes, J and Buyken, Anette and Gilja, OH and Hausken, T and Rosendahl-Riise, H}, year={2024}, pages={101} }' chicago: 'Revheim, I, S Ballance, AF Standal, A Rieder, J Dierkes, Anette Buyken, OH Gilja, T Hausken, and H Rosendahl-Riise. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutr Metab (Lond) 21, no. 1 (2024): 101.' ieee: 'I. Revheim et al., “Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.,” Nutr Metab (Lond), vol. 21, no. 1, p. 101, 2024.' mla: 'Revheim, I., et al. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutr Metab (Lond), vol. 21, no. 1, 2024, p. 101.' short: I. Revheim, S. Ballance, A. Standal, A. Rieder, J. Dierkes, A. Buyken, O. Gilja, T. Hausken, H. Rosendahl-Riise, Nutr Metab (Lond) 21 (2024) 101. date_created: 2025-06-11T08:44:13Z date_updated: 2025-06-11T08:45:02Z external_id: pmid: - '39633450' intvolume: ' 21' issue: '1' language: - iso: eng page: '101' pmid: '1' publication: Nutr Metab (Lond) publication_identifier: issn: - 1743-7075 status: public title: 'Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults.' type: journal_article user_id: '92491' volume: 21 year: '2024' ... --- _id: '62902' article_number: '101' author: - first_name: Ingrid full_name: Revheim, Ingrid last_name: Revheim - first_name: Simon full_name: Ballance, Simon last_name: Ballance - first_name: Adelheid Fretland full_name: Standal, Adelheid Fretland last_name: Standal - first_name: Anne full_name: Rieder, Anne last_name: Rieder - first_name: Jutta full_name: Dierkes, Jutta last_name: Dierkes - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Odd Helge full_name: Gilja, Odd Helge last_name: Gilja - first_name: Trygve full_name: Hausken, Trygve last_name: Hausken - first_name: Hanne full_name: Rosendahl-Riise, Hanne last_name: Rosendahl-Riise citation: ama: 'Revheim I, Ballance S, Standal AF, et al. Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutrition &amp; Metabolism. 2024;21(1). doi:10.1186/s12986-024-00872-2' apa: 'Revheim, I., Ballance, S., Standal, A. F., Rieder, A., Dierkes, J., Buyken, A., Gilja, O. H., Hausken, T., & Rosendahl-Riise, H. (2024). Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults. Nutrition &amp; Metabolism, 21(1), Article 101. https://doi.org/10.1186/s12986-024-00872-2' bibtex: '@article{Revheim_Ballance_Standal_Rieder_Dierkes_Buyken_Gilja_Hausken_Rosendahl-Riise_2024, title={Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults}, volume={21}, DOI={10.1186/s12986-024-00872-2}, number={1101}, journal={Nutrition &amp; Metabolism}, publisher={Springer Science and Business Media LLC}, author={Revheim, Ingrid and Ballance, Simon and Standal, Adelheid Fretland and Rieder, Anne and Dierkes, Jutta and Buyken, Anette and Gilja, Odd Helge and Hausken, Trygve and Rosendahl-Riise, Hanne}, year={2024} }' chicago: 'Revheim, Ingrid, Simon Ballance, Adelheid Fretland Standal, Anne Rieder, Jutta Dierkes, Anette Buyken, Odd Helge Gilja, Trygve Hausken, and Hanne Rosendahl-Riise. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutrition &amp; Metabolism 21, no. 1 (2024). https://doi.org/10.1186/s12986-024-00872-2.' ieee: 'I. Revheim et al., “Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults,” Nutrition &amp; Metabolism, vol. 21, no. 1, Art. no. 101, 2024, doi: 10.1186/s12986-024-00872-2.' mla: 'Revheim, Ingrid, et al. “Correction: The Acute Effect of a β-Glucan-Enriched Oat Bread on Gastric Emptying, GLP-1 Response, and Postprandial Glycaemia and Insulinemia: A Randomised Crossover Trial in Healthy Adults.” Nutrition &amp; Metabolism, vol. 21, no. 1, 101, Springer Science and Business Media LLC, 2024, doi:10.1186/s12986-024-00872-2.' short: I. Revheim, S. Ballance, A.F. Standal, A. Rieder, J. Dierkes, A. Buyken, O.H. Gilja, T. Hausken, H. Rosendahl-Riise, Nutrition &amp; Metabolism 21 (2024). date_created: 2025-12-04T14:41:20Z date_updated: 2025-12-04T14:41:37Z doi: 10.1186/s12986-024-00872-2 intvolume: ' 21' issue: '1' language: - iso: eng publication: Nutrition & Metabolism publication_identifier: issn: - 1743-7075 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults' type: journal_article user_id: '92491' volume: 21 year: '2024' ...