@article{35308,
abstract = {{IntroductionIn 2012, the estimated global prevalence of pre-diabetes was 280 million, and the prevalence is expected to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans, which have been shown to lower postprandial blood glucose. Studies to evaluate the effectiveness of the long-term intake of beta-glucan-enriched bread as part of a habitual diet among individuals with pre-diabetes are needed. Therefore, we designed a multicentre intervention study in adults with pre-diabetes to investigate the effects of consumption of an oat-derived beta-glucan-enriched bread as part of a normal diet on glycated haemoglobin (HbA1c) in comparison to consumption of whole-grain wheat bread.Methods and analysisThe CarbHealth trial is a multicentre double-blind randomised controlled 16-week dietary intervention trial in participants 40–70 years of age with a body mass index of ≥27 kg/m2 and HbA1c of 35–50 mmol/mol. The study is conducted at four universities located in Norway, Sweden and Germany and uses intervention breads specifically designed for the trial by Nofima AS. The aim is to recruit 250 participants. The primary outcome is the difference in HbA1c between the intervention and the control groups. The main analysis will include intervention group, study centre and baseline HbA1c as independent variables in an analysis of covariance model.Ethics and disseminationThe study protocol was approved by respective ethical authorities in participating countries. The results of the study will be communicated through publication in international scientific journals and presentations at (inter)national conferences.Trial registration numberNCT04994327.}},
author = {{Hjorth, Therese and Schadow, Alena and Revheim, Ingrid and Spielau, Ulrike and Thomassen, Lise M and Meyer, Klara and Piotrowski, Katja and Rosendahl-Riise, Hanne and Rieder, Anne and Varela, Paula and Lysne, Vegard and Ballance, Simon and Koerner, Antje and Landberg, Rikard and Buyken, Anette and Dierkes, Jutta}},
issn = {{2044-6055}},
journal = {{BMJ Open}},
keywords = {{General Medicine}},
number = {{8}},
publisher = {{BMJ}},
title = {{{Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucan-enriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study}}},
doi = {{10.1136/bmjopen-2022-062066}},
volume = {{12}},
year = {{2022}},
}
@article{37828,
abstract = {{IntroductionNursing staff is burdened by high workload and stress. Furthermore, heavy lifting, as well as transferring nursing home residents, cause lumbar tissue damage and back pain. Exercise intervention studies to reduce work-related problems are rare and the evidence for efficacy of studies among nurses is limited. Studies including targeted analysis of requirements are necessary to generate effective recommendations and tailored interventions for health promotion programmes. The purpose of this multicentred intervention study is to identify work-related problems, to implement health promotion programmes and to evaluate their effectiveness.Methods and analysisA randomised controlled trial will be conducted, including a total of 48 nursing home facilities in eight regions of Germany with an estimated sample size of 700 nurses. Standardised ergonomics and posture training (10 weeks, once a week for 20–30 min) and subsequently, back-fitness training (12 weeks, once a week for 45–60 min) will be administered. Following the implementation of standardised health promotion programmes, further demand-oriented interventions can be implemented. The perceived exposure to work-related demands, work-related pain in different parts of the body, health-related quality of life, perceived stress, work-related patterns of behaviour and experience, presentism behaviour, work environment as well as general needs and barriers to health promotion, will be assessed at baseline (pre-test), at 10 weeks (post-test, after ergonomics training), at 22 weeks (post-test, after back-fitness training) and at 34 weeks of the programme (follow-up).Ethics and disseminationThe study was reviewed and approved by the local ethics committee of the University of Hamburg (AZ: 2018_168). The results of the study will be published in open-access and international journals. Furthermore, the results will be presented in the participating nursing homes and at national and international conferences.Trial registration numberDRKS.de (DRKS00015241).}},
author = {{Otto, Ann-Kathrin and Pietschmann, Juliane and Appelles, Luisa-Marie and Bebenek, Michael and Bischoff, Laura L and Hildebrand, Claudia and Johnen, Bettina and Jöllenbeck, Thomas and Kemmler, Wolfgang and Klotzbier, Thomas and Korbus, Heide and Rudisch, Julian and Schott, Nadja and Schoene, Daniel and Voelcker-Rehage, Claudia and Vogel, Oliver and Vogt, Lutz and Weigelt, Matthias and Wilke, Jan and Zwingmann, Katharina and Wollesen, Bettina}},
issn = {{2044-6055}},
journal = {{BMJ Open}},
keywords = {{General Medicine}},
number = {{10}},
publisher = {{BMJ}},
title = {{{Physical activity and health promotion for nursing staff in elderly care: a study protocol for a randomised controlled trial}}},
doi = {{10.1136/bmjopen-2020-038202}},
volume = {{10}},
year = {{2020}},
}