---
_id: '35308'
abstract:
- lang: eng
text: IntroductionIn 2012, the estimated
global prevalence of pre-diabetes was 280 million, and the prevalence is expected
to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans,
which have been shown to lower postprandial blood glucose. Studies to evaluate
the effectiveness of the long-term intake of beta-glucan-enriched bread as part
of a habitual diet among individuals with pre-diabetes are needed. Therefore,
we designed a multicentre intervention study in adults with pre-diabetes to investigate
the effects of consumption of an oat-derived beta-glucan-enriched bread as part
of a normal diet on glycated haemoglobin (HbA1c) in comparison to consumption
of whole-grain wheat bread.Methods and
analysisThe CarbHealth trial is a multicentre double-blind
randomised controlled 16-week dietary intervention trial in participants 40–70
years of age with a body mass index of ≥27 kg/m2 and HbA1c
of 35–50 mmol/mol. The study is conducted at four universities located in Norway,
Sweden and Germany and uses intervention breads specifically designed for the
trial by Nofima AS. The aim is to recruit 250 participants. The primary outcome
is the difference in HbA1c between the intervention and the control groups. The
main analysis will include intervention group, study centre and baseline HbA1c
as independent variables in an analysis of covariance model.Ethics
and disseminationThe study protocol was approved by respective
ethical authorities in participating countries. The results of the study will
be communicated through publication in international scientific journals and presentations
at (inter)national conferences.Trial
registration numberNCT04994327.
article_number: e062066
author:
- first_name: Therese
full_name: Hjorth, Therese
last_name: Hjorth
- first_name: Alena
full_name: Schadow, Alena
last_name: Schadow
- first_name: Ingrid
full_name: Revheim, Ingrid
last_name: Revheim
- first_name: Ulrike
full_name: Spielau, Ulrike
last_name: Spielau
- first_name: Lise M
full_name: Thomassen, Lise M
last_name: Thomassen
- first_name: Klara
full_name: Meyer, Klara
last_name: Meyer
- first_name: Katja
full_name: Piotrowski, Katja
last_name: Piotrowski
- first_name: Hanne
full_name: Rosendahl-Riise, Hanne
last_name: Rosendahl-Riise
- first_name: Anne
full_name: Rieder, Anne
last_name: Rieder
- first_name: Paula
full_name: Varela, Paula
last_name: Varela
- first_name: Vegard
full_name: Lysne, Vegard
last_name: Lysne
- first_name: Simon
full_name: Ballance, Simon
last_name: Ballance
- first_name: Antje
full_name: Koerner, Antje
last_name: Koerner
- first_name: Rikard
full_name: Landberg, Rikard
last_name: Landberg
- first_name: Anette
full_name: Buyken, Anette
id: '65985'
last_name: Buyken
- first_name: Jutta
full_name: Dierkes, Jutta
last_name: Dierkes
citation:
ama: 'Hjorth T, Schadow A, Revheim I, et al. Sixteen-week multicentre randomised
controlled trial to study the effect of the consumption of an oat beta-glucan-enriched
bread versus a whole-grain wheat bread on glycaemic control among persons with
pre-diabetes: a study protocol of the CarbHealth study. BMJ Open. 2022;12(8).
doi:10.1136/bmjopen-2022-062066'
apa: 'Hjorth, T., Schadow, A., Revheim, I., Spielau, U., Thomassen, L. M., Meyer,
K., Piotrowski, K., Rosendahl-Riise, H., Rieder, A., Varela, P., Lysne, V., Ballance,
S., Koerner, A., Landberg, R., Buyken, A., & Dierkes, J. (2022). Sixteen-week
multicentre randomised controlled trial to study the effect of the consumption
of an oat beta-glucan-enriched bread versus a whole-grain wheat bread on glycaemic
control among persons with pre-diabetes: a study protocol of the CarbHealth study.
BMJ Open, 12(8), Article e062066. https://doi.org/10.1136/bmjopen-2022-062066'
bibtex: '@article{Hjorth_Schadow_Revheim_Spielau_Thomassen_Meyer_Piotrowski_Rosendahl-Riise_Rieder_Varela_et
al._2022, title={Sixteen-week multicentre randomised controlled trial to study
the effect of the consumption of an oat beta-glucan-enriched bread versus a whole-grain
wheat bread on glycaemic control among persons with pre-diabetes: a study protocol
of the CarbHealth study}, volume={12}, DOI={10.1136/bmjopen-2022-062066},
number={8e062066}, journal={BMJ Open}, publisher={BMJ}, author={Hjorth, Therese
and Schadow, Alena and Revheim, Ingrid and Spielau, Ulrike and Thomassen, Lise
M and Meyer, Klara and Piotrowski, Katja and Rosendahl-Riise, Hanne and Rieder,
Anne and Varela, Paula and et al.}, year={2022} }'
chicago: 'Hjorth, Therese, Alena Schadow, Ingrid Revheim, Ulrike Spielau, Lise M
Thomassen, Klara Meyer, Katja Piotrowski, et al. “Sixteen-Week Multicentre Randomised
Controlled Trial to Study the Effect of the Consumption of an Oat Beta-Glucan-Enriched
Bread versus a Whole-Grain Wheat Bread on Glycaemic Control among Persons with
Pre-Diabetes: A Study Protocol of the CarbHealth Study.” BMJ Open 12, no.
8 (2022). https://doi.org/10.1136/bmjopen-2022-062066.'
ieee: 'T. Hjorth et al., “Sixteen-week multicentre randomised controlled
trial to study the effect of the consumption of an oat beta-glucan-enriched bread
versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes:
a study protocol of the CarbHealth study,” BMJ Open, vol. 12, no. 8, Art.
no. e062066, 2022, doi: 10.1136/bmjopen-2022-062066.'
mla: 'Hjorth, Therese, et al. “Sixteen-Week Multicentre Randomised Controlled Trial
to Study the Effect of the Consumption of an Oat Beta-Glucan-Enriched Bread versus
a Whole-Grain Wheat Bread on Glycaemic Control among Persons with Pre-Diabetes:
A Study Protocol of the CarbHealth Study.” BMJ Open, vol. 12, no. 8, e062066,
BMJ, 2022, doi:10.1136/bmjopen-2022-062066.'
short: T. Hjorth, A. Schadow, I. Revheim, U. Spielau, L.M. Thomassen, K. Meyer,
K. Piotrowski, H. Rosendahl-Riise, A. Rieder, P. Varela, V. Lysne, S. Ballance,
A. Koerner, R. Landberg, A. Buyken, J. Dierkes, BMJ Open 12 (2022).
date_created: 2023-01-05T16:31:47Z
date_updated: 2023-01-05T16:47:45Z
department:
- _id: '35'
- _id: '17'
- _id: '22'
- _id: '571'
doi: 10.1136/bmjopen-2022-062066
intvolume: ' 12'
issue: '8'
keyword:
- General Medicine
language:
- iso: eng
publication: BMJ Open
publication_identifier:
issn:
- 2044-6055
- 2044-6055
publication_status: published
publisher: BMJ
status: public
title: 'Sixteen-week multicentre randomised controlled trial to study the effect of
the consumption of an oat beta-glucan-enriched bread versus a whole-grain wheat
bread on glycaemic control among persons with pre-diabetes: a study protocol of
the CarbHealth study'
type: journal_article
user_id: '61597'
volume: 12
year: '2022'
...
---
_id: '37828'
abstract:
- lang: eng
text: 'IntroductionNursing staff is burdened
by high workload and stress. Furthermore, heavy lifting, as well as transferring
nursing home residents, cause lumbar tissue damage and back pain. Exercise intervention
studies to reduce work-related problems are rare and the evidence for efficacy
of studies among nurses is limited. Studies including targeted analysis of requirements
are necessary to generate effective recommendations and tailored interventions
for health promotion programmes. The purpose of this multicentred intervention
study is to identify work-related problems, to implement health promotion programmes
and to evaluate their effectiveness.Methods
and analysisA randomised controlled trial will be conducted,
including a total of 48 nursing home facilities in eight regions of Germany with
an estimated sample size of 700 nurses. Standardised ergonomics and posture training
(10 weeks, once a week for 20–30 min) and subsequently, back-fitness training
(12 weeks, once a week for 45–60 min) will be administered. Following the implementation
of standardised health promotion programmes, further demand-oriented interventions
can be implemented. The perceived exposure to work-related demands, work-related
pain in different parts of the body, health-related quality of life, perceived
stress, work-related patterns of behaviour and experience, presentism behaviour,
work environment as well as general needs and barriers to health promotion, will
be assessed at baseline (pre-test), at 10 weeks (post-test, after ergonomics training),
at 22 weeks (post-test, after back-fitness training) and at 34 weeks of the programme
(follow-up).Ethics and disseminationThe
study was reviewed and approved by the local ethics committee of the University
of Hamburg (AZ: 2018_168). The results of the study will be published in open-access
and international journals. Furthermore, the results will be presented in the
participating nursing homes and at national and international conferences.Trial
registration numberDRKS.de (DRKS00015241).'
article_number: e038202
author:
- first_name: Ann-Kathrin
full_name: Otto, Ann-Kathrin
last_name: Otto
- first_name: Juliane
full_name: Pietschmann, Juliane
last_name: Pietschmann
- first_name: Luisa-Marie
full_name: Appelles, Luisa-Marie
last_name: Appelles
- first_name: Michael
full_name: Bebenek, Michael
last_name: Bebenek
- first_name: Laura L
full_name: Bischoff, Laura L
last_name: Bischoff
- first_name: Claudia
full_name: Hildebrand, Claudia
last_name: Hildebrand
- first_name: Bettina
full_name: Johnen, Bettina
last_name: Johnen
- first_name: Thomas
full_name: Jöllenbeck, Thomas
last_name: Jöllenbeck
- first_name: Wolfgang
full_name: Kemmler, Wolfgang
last_name: Kemmler
- first_name: Thomas
full_name: Klotzbier, Thomas
last_name: Klotzbier
- first_name: Heide
full_name: Korbus, Heide
last_name: Korbus
- first_name: Julian
full_name: Rudisch, Julian
last_name: Rudisch
- first_name: Nadja
full_name: Schott, Nadja
last_name: Schott
- first_name: Daniel
full_name: Schoene, Daniel
last_name: Schoene
- first_name: Claudia
full_name: Voelcker-Rehage, Claudia
last_name: Voelcker-Rehage
- first_name: Oliver
full_name: Vogel, Oliver
last_name: Vogel
- first_name: Lutz
full_name: Vogt, Lutz
last_name: Vogt
- first_name: Matthias
full_name: Weigelt, Matthias
id: '36388'
last_name: Weigelt
- first_name: Jan
full_name: Wilke, Jan
last_name: Wilke
- first_name: Katharina
full_name: Zwingmann, Katharina
last_name: Zwingmann
- first_name: Bettina
full_name: Wollesen, Bettina
last_name: Wollesen
citation:
ama: 'Otto A-K, Pietschmann J, Appelles L-M, et al. Physical activity and health
promotion for nursing staff in elderly care: a study protocol for a randomised
controlled trial. BMJ Open. 2020;10(10). doi:10.1136/bmjopen-2020-038202'
apa: 'Otto, A.-K., Pietschmann, J., Appelles, L.-M., Bebenek, M., Bischoff, L. L.,
Hildebrand, C., Johnen, B., Jöllenbeck, T., Kemmler, W., Klotzbier, T., Korbus,
H., Rudisch, J., Schott, N., Schoene, D., Voelcker-Rehage, C., Vogel, O., Vogt,
L., Weigelt, M., Wilke, J., … Wollesen, B. (2020). Physical activity and health
promotion for nursing staff in elderly care: a study protocol for a randomised
controlled trial. BMJ Open, 10(10), Article e038202. https://doi.org/10.1136/bmjopen-2020-038202'
bibtex: '@article{Otto_Pietschmann_Appelles_Bebenek_Bischoff_Hildebrand_Johnen_Jöllenbeck_Kemmler_Klotzbier_et
al._2020, title={Physical activity and health promotion for nursing staff in elderly
care: a study protocol for a randomised controlled trial}, volume={10}, DOI={10.1136/bmjopen-2020-038202},
number={10e038202}, journal={BMJ Open}, publisher={BMJ}, author={Otto, Ann-Kathrin
and Pietschmann, Juliane and Appelles, Luisa-Marie and Bebenek, Michael and Bischoff,
Laura L and Hildebrand, Claudia and Johnen, Bettina and Jöllenbeck, Thomas and
Kemmler, Wolfgang and Klotzbier, Thomas and et al.}, year={2020} }'
chicago: 'Otto, Ann-Kathrin, Juliane Pietschmann, Luisa-Marie Appelles, Michael
Bebenek, Laura L Bischoff, Claudia Hildebrand, Bettina Johnen, et al. “Physical
Activity and Health Promotion for Nursing Staff in Elderly Care: A Study Protocol
for a Randomised Controlled Trial.” BMJ Open 10, no. 10 (2020). https://doi.org/10.1136/bmjopen-2020-038202.'
ieee: 'A.-K. Otto et al., “Physical activity and health promotion for nursing
staff in elderly care: a study protocol for a randomised controlled trial,” BMJ
Open, vol. 10, no. 10, Art. no. e038202, 2020, doi: 10.1136/bmjopen-2020-038202.'
mla: 'Otto, Ann-Kathrin, et al. “Physical Activity and Health Promotion for Nursing
Staff in Elderly Care: A Study Protocol for a Randomised Controlled Trial.” BMJ
Open, vol. 10, no. 10, e038202, BMJ, 2020, doi:10.1136/bmjopen-2020-038202.'
short: A.-K. Otto, J. Pietschmann, L.-M. Appelles, M. Bebenek, L.L. Bischoff, C.
Hildebrand, B. Johnen, T. Jöllenbeck, W. Kemmler, T. Klotzbier, H. Korbus, J.
Rudisch, N. Schott, D. Schoene, C. Voelcker-Rehage, O. Vogel, L. Vogt, M. Weigelt,
J. Wilke, K. Zwingmann, B. Wollesen, BMJ Open 10 (2020).
date_created: 2023-01-21T13:32:54Z
date_updated: 2023-01-23T13:29:21Z
department:
- _id: '266'
doi: 10.1136/bmjopen-2020-038202
intvolume: ' 10'
issue: '10'
keyword:
- General Medicine
language:
- iso: eng
publication: BMJ Open
publication_identifier:
issn:
- 2044-6055
- 2044-6055
publication_status: published
publisher: BMJ
quality_controlled: '1'
status: public
title: 'Physical activity and health promotion for nursing staff in elderly care:
a study protocol for a randomised controlled trial'
type: journal_article
user_id: '75770'
volume: 10
year: '2020'
...