---
_id: '40154'
abstract:
- lang: eng
text: The development of bioresorbable materials for temporary implantation
enables progress in medical technology. Iron (Fe)-based degradable materials are
biocompatible and exhibit good mechanical properties, but their degradation rate
is low. Aside from alloying with Manganese (Mn), the creation of phases with high
electrochemical potential such as silver (Ag) phases to cause the anodic dissolution
of FeMn is promising. However, to enable residue-free dissolution, the Ag needs
to be modified. This concern is addressed, as FeMn modified with a degradable
Ag-Calcium-Lanthanum (AgCaLa) alloy is investigated. The electrochemical properties
and the degradation behavior are determined via a static immersion test. The local
differences in electrochemical potential increase the degradation rate (low pH
values), and the formation of gaps around the Ag phases (neutral pH values) demonstrates
the benefit of the strategy. Nevertheless, the formation of corrosion-inhibiting
layers avoids an increased degradation rate under a neutral pH value. The complete
bioresorption of the material is possible since the phases of the degradable AgCaLa
alloy dissolve after the FeMn matrix. Cell viability tests reveal biocompatibility,
and the antibacterial activity of the degradation supernatant is observed. Thus,
FeMn modified with degradable AgCaLa phases is promising as a bioresorbable material
if corrosion-inhibiting layers can be diminished.
author:
- first_name: Jan Tobias
full_name: Krüger, Jan Tobias
id: '44307'
last_name: Krüger
orcid: 0000-0002-0827-9654
- first_name: Kay-Peter
full_name: Hoyer, Kay-Peter
id: '48411'
last_name: Hoyer
- first_name: Jingyuan
full_name: Huang, Jingyuan
last_name: Huang
- first_name: Viviane
full_name: Filor, Viviane
last_name: Filor
- first_name: Rafael Hernan
full_name: Mateus-Vargas, Rafael Hernan
last_name: Mateus-Vargas
- first_name: Hilke
full_name: Oltmanns, Hilke
last_name: Oltmanns
- first_name: Jessica
full_name: Meißner, Jessica
last_name: Meißner
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Mirko
full_name: Schaper, Mirko
id: '43720'
last_name: Schaper
citation:
ama: Krüger JT, Hoyer K-P, Huang J, et al. FeMn with Phases of a Degradable Ag Alloy
for Residue-Free and Adapted Bioresorbability. Journal of Functional Biomaterials.
2022;13(4):185. doi:10.3390/jfb13040185
apa: Krüger, J. T., Hoyer, K.-P., Huang, J., Filor, V., Mateus-Vargas, R. H., Oltmanns,
H., Meißner, J., Grundmeier, G., & Schaper, M. (2022). FeMn with Phases of
a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability. Journal
of Functional Biomaterials, 13(4), 185. https://doi.org/10.3390/jfb13040185
bibtex: '@article{Krüger_Hoyer_Huang_Filor_Mateus-Vargas_Oltmanns_Meißner_Grundmeier_Schaper_2022,
title={FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability}, volume={13}, DOI={10.3390/jfb13040185},
number={4}, journal={Journal of Functional Biomaterials}, publisher={MDPI AG},
author={Krüger, Jan Tobias and Hoyer, Kay-Peter and Huang, Jingyuan and Filor,
Viviane and Mateus-Vargas, Rafael Hernan and Oltmanns, Hilke and Meißner, Jessica
and Grundmeier, Guido and Schaper, Mirko}, year={2022}, pages={185} }'
chicago: 'Krüger, Jan Tobias, Kay-Peter Hoyer, Jingyuan Huang, Viviane Filor, Rafael
Hernan Mateus-Vargas, Hilke Oltmanns, Jessica Meißner, Guido Grundmeier, and Mirko
Schaper. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability.” Journal of Functional Biomaterials 13, no. 4 (2022):
185. https://doi.org/10.3390/jfb13040185.'
ieee: 'J. T. Krüger et al., “FeMn with Phases of a Degradable Ag Alloy for
Residue-Free and Adapted Bioresorbability,” Journal of Functional Biomaterials,
vol. 13, no. 4, p. 185, 2022, doi: 10.3390/jfb13040185.'
mla: Krüger, Jan Tobias, et al. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free
and Adapted Bioresorbability.” Journal of Functional Biomaterials, vol.
13, no. 4, MDPI AG, 2022, p. 185, doi:10.3390/jfb13040185.
short: J.T. Krüger, K.-P. Hoyer, J. Huang, V. Filor, R.H. Mateus-Vargas, H. Oltmanns,
J. Meißner, G. Grundmeier, M. Schaper, Journal of Functional Biomaterials 13 (2022)
185.
date_created: 2023-01-26T06:39:42Z
date_updated: 2023-04-27T16:39:26Z
department:
- _id: '302'
- _id: '158'
doi: 10.3390/jfb13040185
intvolume: ' 13'
issue: '4'
keyword:
- Biomedical Engineering
- Biomaterials
language:
- iso: eng
page: '185'
publication: Journal of Functional Biomaterials
publication_identifier:
issn:
- 2079-4983
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
status: public
title: FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability
type: journal_article
user_id: '43720'
volume: 13
year: '2022'
...
---
_id: '33723'
abstract:
- lang: eng
text: The development of bioresorbable materials for temporary implantation
enables progress in medical technology. Iron (Fe)-based degradable materials are
biocompatible and exhibit good mechanical properties, but their degradation rate
is low. Aside from alloying with Manganese (Mn), the creation of phases with high
electrochemical potential such as silver (Ag) phases to cause the anodic dissolution
of FeMn is promising. However, to enable residue-free dissolution, the Ag needs
to be modified. This concern is addressed, as FeMn modified with a degradable
Ag-Calcium-Lanthanum (AgCaLa) alloy is investigated. The electrochemical properties
and the degradation behavior are determined via a static immersion test. The local
differences in electrochemical potential increase the degradation rate (low pH
values), and the formation of gaps around the Ag phases (neutral pH values) demonstrates
the benefit of the strategy. Nevertheless, the formation of corrosion-inhibiting
layers avoids an increased degradation rate under a neutral pH value. The complete
bioresorption of the material is possible since the phases of the degradable AgCaLa
alloy dissolve after the FeMn matrix. Cell viability tests reveal biocompatibility,
and the antibacterial activity of the degradation supernatant is observed. Thus,
FeMn modified with degradable AgCaLa phases is promising as a bioresorbable material
if corrosion-inhibiting layers can be diminished.
article_number: '185'
author:
- first_name: Jan Tobias
full_name: Krüger, Jan Tobias
id: '44307'
last_name: Krüger
orcid: 0000-0002-0827-9654
- first_name: Kay-Peter
full_name: Hoyer, Kay-Peter
id: '48411'
last_name: Hoyer
- first_name: Jingyuan
full_name: Huang, Jingyuan
last_name: Huang
- first_name: Viviane
full_name: Filor, Viviane
last_name: Filor
- first_name: Rafael Hernan
full_name: Mateus-Vargas, Rafael Hernan
last_name: Mateus-Vargas
- first_name: Hilke
full_name: Oltmanns, Hilke
last_name: Oltmanns
- first_name: Jessica
full_name: Meißner, Jessica
last_name: Meißner
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Mirko
full_name: Schaper, Mirko
id: '43720'
last_name: Schaper
citation:
ama: Krüger JT, Hoyer K-P, Huang J, et al. FeMn with Phases of a Degradable Ag Alloy
for Residue-Free and Adapted Bioresorbability. Journal of Functional Biomaterials.
2022;13(4). doi:10.3390/jfb13040185
apa: Krüger, J. T., Hoyer, K.-P., Huang, J., Filor, V., Mateus-Vargas, R. H., Oltmanns,
H., Meißner, J., Grundmeier, G., & Schaper, M. (2022). FeMn with Phases of
a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability. Journal
of Functional Biomaterials, 13(4), Article 185. https://doi.org/10.3390/jfb13040185
bibtex: '@article{Krüger_Hoyer_Huang_Filor_Mateus-Vargas_Oltmanns_Meißner_Grundmeier_Schaper_2022,
title={FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability}, volume={13}, DOI={10.3390/jfb13040185},
number={4185}, journal={Journal of Functional Biomaterials}, publisher={MDPI AG},
author={Krüger, Jan Tobias and Hoyer, Kay-Peter and Huang, Jingyuan and Filor,
Viviane and Mateus-Vargas, Rafael Hernan and Oltmanns, Hilke and Meißner, Jessica
and Grundmeier, Guido and Schaper, Mirko}, year={2022} }'
chicago: Krüger, Jan Tobias, Kay-Peter Hoyer, Jingyuan Huang, Viviane Filor, Rafael
Hernan Mateus-Vargas, Hilke Oltmanns, Jessica Meißner, Guido Grundmeier, and Mirko
Schaper. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability.” Journal of Functional Biomaterials 13, no. 4 (2022).
https://doi.org/10.3390/jfb13040185.
ieee: 'J. T. Krüger et al., “FeMn with Phases of a Degradable Ag Alloy for
Residue-Free and Adapted Bioresorbability,” Journal of Functional Biomaterials,
vol. 13, no. 4, Art. no. 185, 2022, doi: 10.3390/jfb13040185.'
mla: Krüger, Jan Tobias, et al. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free
and Adapted Bioresorbability.” Journal of Functional Biomaterials, vol.
13, no. 4, 185, MDPI AG, 2022, doi:10.3390/jfb13040185.
short: J.T. Krüger, K.-P. Hoyer, J. Huang, V. Filor, R.H. Mateus-Vargas, H. Oltmanns,
J. Meißner, G. Grundmeier, M. Schaper, Journal of Functional Biomaterials 13 (2022).
date_created: 2022-10-14T07:18:50Z
date_updated: 2023-04-27T16:41:07Z
department:
- _id: '9'
- _id: '158'
doi: 10.3390/jfb13040185
intvolume: ' 13'
issue: '4'
keyword:
- Biomedical Engineering
- Biomaterials
language:
- iso: eng
publication: Journal of Functional Biomaterials
publication_identifier:
issn:
- 2079-4983
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
status: public
title: FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability
type: journal_article
user_id: '43720'
volume: 13
year: '2022'
...
---
_id: '41494'
abstract:
- lang: eng
text: The development of bioresorbable materials for temporary implantation
enables progress in medical technology. Iron (Fe)-based degradable materials are
biocompatible and exhibit good mechanical properties, but their degradation rate
is low. Aside from alloying with Manganese (Mn), the creation of phases with high
electrochemical potential such as silver (Ag) phases to cause the anodic dissolution
of FeMn is promising. However, to enable residue-free dissolution, the Ag needs
to be modified. This concern is addressed, as FeMn modified with a degradable
Ag-Calcium-Lanthanum (AgCaLa) alloy is investigated. The electrochemical properties
and the degradation behavior are determined via a static immersion test. The local
differences in electrochemical potential increase the degradation rate (low pH
values), and the formation of gaps around the Ag phases (neutral pH values) demonstrates
the benefit of the strategy. Nevertheless, the formation of corrosion-inhibiting
layers avoids an increased degradation rate under a neutral pH value. The complete
bioresorption of the material is possible since the phases of the degradable AgCaLa
alloy dissolve after the FeMn matrix. Cell viability tests reveal biocompatibility,
and the antibacterial activity of the degradation supernatant is observed. Thus,
FeMn modified with degradable AgCaLa phases is promising as a bioresorbable material
if corrosion-inhibiting layers can be diminished.
article_number: '185'
author:
- first_name: Jan Tobias
full_name: Krüger, Jan Tobias
id: '44307'
last_name: Krüger
orcid: 0000-0002-0827-9654
- first_name: Kay-Peter
full_name: Hoyer, Kay-Peter
id: '48411'
last_name: Hoyer
- first_name: Jingyuan
full_name: Huang, Jingyuan
last_name: Huang
- first_name: Viviane
full_name: Filor, Viviane
last_name: Filor
- first_name: Rafael Hernan
full_name: Mateus-Vargas, Rafael Hernan
last_name: Mateus-Vargas
- first_name: Hilke
full_name: Oltmanns, Hilke
last_name: Oltmanns
- first_name: Jessica
full_name: Meißner, Jessica
last_name: Meißner
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Mirko
full_name: Schaper, Mirko
id: '43720'
last_name: Schaper
citation:
ama: Krüger JT, Hoyer K-P, Huang J, et al. FeMn with Phases of a Degradable Ag Alloy
for Residue-Free and Adapted Bioresorbability. Journal of Functional Biomaterials.
2022;13(4). doi:10.3390/jfb13040185
apa: Krüger, J. T., Hoyer, K.-P., Huang, J., Filor, V., Mateus-Vargas, R. H., Oltmanns,
H., Meißner, J., Grundmeier, G., & Schaper, M. (2022). FeMn with Phases of
a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability. Journal
of Functional Biomaterials, 13(4), Article 185. https://doi.org/10.3390/jfb13040185
bibtex: '@article{Krüger_Hoyer_Huang_Filor_Mateus-Vargas_Oltmanns_Meißner_Grundmeier_Schaper_2022,
title={FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability}, volume={13}, DOI={10.3390/jfb13040185},
number={4185}, journal={Journal of Functional Biomaterials}, publisher={MDPI AG},
author={Krüger, Jan Tobias and Hoyer, Kay-Peter and Huang, Jingyuan and Filor,
Viviane and Mateus-Vargas, Rafael Hernan and Oltmanns, Hilke and Meißner, Jessica
and Grundmeier, Guido and Schaper, Mirko}, year={2022} }'
chicago: Krüger, Jan Tobias, Kay-Peter Hoyer, Jingyuan Huang, Viviane Filor, Rafael
Hernan Mateus-Vargas, Hilke Oltmanns, Jessica Meißner, Guido Grundmeier, and Mirko
Schaper. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted
Bioresorbability.” Journal of Functional Biomaterials 13, no. 4 (2022).
https://doi.org/10.3390/jfb13040185.
ieee: 'J. T. Krüger et al., “FeMn with Phases of a Degradable Ag Alloy for
Residue-Free and Adapted Bioresorbability,” Journal of Functional Biomaterials,
vol. 13, no. 4, Art. no. 185, 2022, doi: 10.3390/jfb13040185.'
mla: Krüger, Jan Tobias, et al. “FeMn with Phases of a Degradable Ag Alloy for Residue-Free
and Adapted Bioresorbability.” Journal of Functional Biomaterials, vol.
13, no. 4, 185, MDPI AG, 2022, doi:10.3390/jfb13040185.
short: J.T. Krüger, K.-P. Hoyer, J. Huang, V. Filor, R.H. Mateus-Vargas, H. Oltmanns,
J. Meißner, G. Grundmeier, M. Schaper, Journal of Functional Biomaterials 13 (2022).
date_created: 2023-02-02T14:26:25Z
date_updated: 2023-04-27T16:45:32Z
department:
- _id: '9'
- _id: '158'
doi: 10.3390/jfb13040185
intvolume: ' 13'
issue: '4'
keyword:
- Biomedical Engineering
- Biomaterials
language:
- iso: eng
publication: Journal of Functional Biomaterials
publication_identifier:
issn:
- 2079-4983
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
status: public
title: FeMn with Phases of a Degradable Ag Alloy for Residue-Free and Adapted Bioresorbability
type: journal_article
user_id: '43720'
volume: 13
year: '2022'
...