---
_id: '27014'
abstract:
- lang: eng
  text: '<jats:p><jats:bold>Purpose:</jats:bold> To examine the prospective relevance
    of dietary sugar intake (based on dietary data as well as urinary excretion data)
    in adolescent years for insulin sensitivity and biomarkers of inflammation in
    young adulthood.</jats:p><jats:p><jats:bold>Methods:</jats:bold> Overall 254 participants
    of the DONALD study who had at least two 3-day weighed dietary records for calculating
    intakes of fructose, glucose, sucrose, total, free, added sugars, total sugars
    from sugar-sweetened beverages (SSB), juice, and sweets/sugar or at least two
    complete 24 h urine samples (<jats:italic>n</jats:italic> = 221) for calculating
    sugar excretion (urinary fructose and urinary fructose + sucrose) in adolescence
    (females: 9–15 years, males: 10–16 years) and a fasting blood sample in adulthood
    (18–36 years), were included in multivariable linear regression analyses assessing
    their prospective associations with adult homeostasis model assessment insulin
    sensitivity (HOMA2-%S) and a pro-inflammatory score (based on CRP, IL-6, IL-18,
    leptin, chemerin, adiponectin).</jats:p><jats:p><jats:bold>Results:</jats:bold>
    On the dietary intake level, no prospective associations were observed between
    adolescent fructose, sucrose, glucose, added, free, total sugar, or total sugar
    from SSB, juice or sweets/sugar intake and adult HOMA2-%S (<jats:italic>p</jats:italic>
    &amp;gt; 0.01). On the urinary level, however, higher excreted fructose levels
    were associated with improved adult HOMA2-%S (<jats:italic>p</jats:italic> = 0.008)
    among females only. No associations were observed between dietary or urinary sugars
    and the adult pro-inflammatory score (<jats:italic>p</jats:italic> &amp;gt; 0.01).</jats:p><jats:p><jats:bold>Conclusion:</jats:bold>
    The present study did not provide support that dietary sugar consumed in adolescence
    is associated with adult insulin sensitivity. The one potential exception was
    the moderate dietary consumption of fructose, which showed a beneficial association
    with adult fasting insulin and insulin sensitivity.</jats:p>'
author:
- first_name: Karen A.
  full_name: Della Corte, Karen A.
  last_name: Della Corte
- first_name: Katharina
  full_name: Penczynski, Katharina
  last_name: Penczynski
- first_name: Gunter
  full_name: Kuhnle, Gunter
  last_name: Kuhnle
- first_name: Ines
  full_name: Perrar, Ines
  last_name: Perrar
- first_name: Christian
  full_name: Herder, Christian
  last_name: Herder
- first_name: Michael
  full_name: Roden, Michael
  last_name: Roden
- first_name: Stefan A.
  full_name: Wudy, Stefan A.
  last_name: Wudy
- first_name: Thomas
  full_name: Remer, Thomas
  last_name: Remer
- first_name: Ute
  full_name: Alexy, Ute
  last_name: Alexy
- first_name: Anette
  full_name: Buyken, Anette
  id: '65985'
  last_name: Buyken
citation:
  ama: Della Corte KA, Penczynski K, Kuhnle G, et al. The Prospective Association
    of Dietary Sugar Intake in Adolescence With Risk Markers of Type 2 Diabetes in
    Young Adulthood. <i>Frontiers in Nutrition</i>. Published online 2021. doi:<a
    href="https://doi.org/10.3389/fnut.2020.615684">10.3389/fnut.2020.615684</a>
  apa: Della Corte, K. A., Penczynski, K., Kuhnle, G., Perrar, I., Herder, C., Roden,
    M., Wudy, S. A., Remer, T., Alexy, U., &#38; Buyken, A. (2021). The Prospective
    Association of Dietary Sugar Intake in Adolescence With Risk Markers of Type 2
    Diabetes in Young Adulthood. <i>Frontiers in Nutrition</i>. <a href="https://doi.org/10.3389/fnut.2020.615684">https://doi.org/10.3389/fnut.2020.615684</a>
  bibtex: '@article{Della Corte_Penczynski_Kuhnle_Perrar_Herder_Roden_Wudy_Remer_Alexy_Buyken_2021,
    title={The Prospective Association of Dietary Sugar Intake in Adolescence With
    Risk Markers of Type 2 Diabetes in Young Adulthood}, DOI={<a href="https://doi.org/10.3389/fnut.2020.615684">10.3389/fnut.2020.615684</a>},
    journal={Frontiers in Nutrition}, author={Della Corte, Karen A. and Penczynski,
    Katharina and Kuhnle, Gunter and Perrar, Ines and Herder, Christian and Roden,
    Michael and Wudy, Stefan A. and Remer, Thomas and Alexy, Ute and Buyken, Anette},
    year={2021} }'
  chicago: Della Corte, Karen A., Katharina Penczynski, Gunter Kuhnle, Ines Perrar,
    Christian Herder, Michael Roden, Stefan A. Wudy, Thomas Remer, Ute Alexy, and
    Anette Buyken. “The Prospective Association of Dietary Sugar Intake in Adolescence
    With Risk Markers of Type 2 Diabetes in Young Adulthood.” <i>Frontiers in Nutrition</i>,
    2021. <a href="https://doi.org/10.3389/fnut.2020.615684">https://doi.org/10.3389/fnut.2020.615684</a>.
  ieee: 'K. A. Della Corte <i>et al.</i>, “The Prospective Association of Dietary
    Sugar Intake in Adolescence With Risk Markers of Type 2 Diabetes in Young Adulthood,”
    <i>Frontiers in Nutrition</i>, 2021, doi: <a href="https://doi.org/10.3389/fnut.2020.615684">10.3389/fnut.2020.615684</a>.'
  mla: Della Corte, Karen A., et al. “The Prospective Association of Dietary Sugar
    Intake in Adolescence With Risk Markers of Type 2 Diabetes in Young Adulthood.”
    <i>Frontiers in Nutrition</i>, 2021, doi:<a href="https://doi.org/10.3389/fnut.2020.615684">10.3389/fnut.2020.615684</a>.
  short: K.A. Della Corte, K. Penczynski, G. Kuhnle, I. Perrar, C. Herder, M. Roden,
    S.A. Wudy, T. Remer, U. Alexy, A. Buyken, Frontiers in Nutrition (2021).
date_created: 2021-10-29T13:59:00Z
date_updated: 2022-01-06T06:57:32Z
department:
- _id: '17'
- _id: '22'
- _id: '571'
- _id: '35'
doi: 10.3389/fnut.2020.615684
language:
- iso: eng
publication: Frontiers in Nutrition
publication_identifier:
  issn:
  - 2296-861X
publication_status: published
status: public
title: The Prospective Association of Dietary Sugar Intake in Adolescence With Risk
  Markers of Type 2 Diabetes in Young Adulthood
type: journal_article
user_id: '61597'
year: '2021'
...