@article{64873,
  abstract     = {{Continuous flow catalysis utilizing gel-bound organocatalysts within a microfluidic reactor represents a compelling strategy in the realm of organic synthesis. In this study, a quinuclidine-based catalytic monomer (QMA) was synthesized to create polymer gel dots through the process of photopolymerization that serve as a support for the catalyst. The resulting gel-bound organocatalysts were assembled within a continuous microfluidic reactor to facilitate the Baylis–Hillman reaction between various aldehydes and acrylonitrile at a temperature of 50 °C. The conversion of the product was assessed using 1H NMR spectroscopy as an offline analytical method over a duration of 8 h. The findings indicated that highly reactive aldehydes achieved conversion rates exceeding 90%, in contrast to their less reactive counterparts. Furthermore, these results were juxtaposed with previously published data derived from alternative synthetic methodologies, revealing that the continuous microfluidic reactions employing integrated organocatalysts within polymer networks exhibited significantly higher conversions with reduced reaction times (8 h) at the same temperature (50 °C). Additionally, the influence of different geometries (round, triangular, and square) of the gel dots on catalytic activity was investigated, with round and square gel dots demonstrating slightly superior performance compared with triangular gel dots, attributed to their increased surface area. Moreover, an extended reaction period of 6 days was conducted using 4-bromobenzaldehyde and acrylonitrile, resulting in a conversion rate exceeding 70%, which remained stable for 5 days before experiencing a slight decline due to product accumulation on the gel dots.}},
  author       = {{Killi, Naresh and Kumar, Amit and Nebhani, Leena and Obst, Franziska and Richter, Andreas and Reineke Matsudo, Bernhard and Zentgraf, Thomas and Kuckling, Dirk}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  number       = {{9}},
  publisher    = {{American Chemical Society (ACS)}},
  title        = {{{Integrating an Organocatalyst into a Polymeric Gel Framework for the Continuous Microflow Baylis–Hillman Reaction}}},
  doi          = {{10.1021/acsomega.5c09476}},
  volume       = {{11}},
  year         = {{2026}},
}

@article{40563,
  author       = {{Jerigová, Mária and Odziomek, Mateusz and Lopez Salas, Nieves}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  keywords     = {{General Chemical Engineering, General Chemistry}},
  number       = {{14}},
  pages        = {{11544--11554}},
  publisher    = {{American Chemical Society (ACS)}},
  title        = {{{“We Are Here!” Oxygen Functional Groups in Carbons for Electrochemical Applications}}},
  doi          = {{10.1021/acsomega.2c00639}},
  volume       = {{7}},
  year         = {{2022}},
}

@article{37710,
  author       = {{Ruiz Alvarado, Isaac Azahel and Schmidt, Wolf Gero}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  keywords     = {{General Chemical Engineering, General Chemistry}},
  number       = {{23}},
  pages        = {{19355--19364}},
  publisher    = {{American Chemical Society (ACS)}},
  title        = {{{Water/InP(001) from Density Functional Theory}}},
  doi          = {{10.1021/acsomega.2c00948}},
  volume       = {{7}},
  year         = {{2022}},
}

@article{37714,
  author       = {{Karmo, Marsel and Ruiz Alvarado, Isaac Azahel and Schmidt, Wolf Gero and Runge, Erich}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  keywords     = {{General Chemical Engineering, General Chemistry}},
  number       = {{6}},
  pages        = {{5064--5068}},
  publisher    = {{American Chemical Society (ACS)}},
  title        = {{{Reconstructions of the As-Terminated GaAs(001) Surface Exposed to Atomic Hydrogen}}},
  doi          = {{10.1021/acsomega.1c06019}},
  volume       = {{7}},
  year         = {{2022}},
}

@article{22009,
  author       = {{Ruiz Alvarado, Isaac Azahel and Karmo, Marsel and Runge, Erich and Schmidt, Wolf Gero}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{6297--6304}},
  title        = {{{InP and AlInP(001)(2 × 4) Surface Oxidation from Density Functional Theory}}},
  doi          = {{10.1021/acsomega.0c06019}},
  year         = {{2021}},
}

@article{23781,
  author       = {{Patil, Mayurkumar P. and Vaidya, Prakash D. and Kenig, Eugeny}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{27043--27049}},
  title        = {{{Kinetics of Carbon Dioxide Removal Using N-Acetylglucosamine}}},
  doi          = {{10.1021/acsomega.0c02076}},
  volume       = {{5}},
  year         = {{2020}},
}

@article{19654,
  author       = {{Krenz, Marvin and Gerstmann, Uwe and Schmidt, Wolf Gero}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{24057--24063}},
  title        = {{{Photochemical Ring Opening of Oxirane Modeled by Constrained Density Functional Theory}}},
  doi          = {{10.1021/acsomega.0c03483}},
  year         = {{2020}},
}

@article{22657,
  author       = {{Hajiraissi, Roozbeh and Hanke, Marcel and Gonzalez Orive, Alejandro and Duderija, Belma and Hofmann, Ulrike and Zhang, Yixin and Grundmeier, Guido and Keller, Adrian}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{2649--2660}},
  title        = {{{Effect of Terminal Modifications on the Adsorption and Assembly of hIAPP(20–29)}}},
  doi          = {{10.1021/acsomega.8b03028}},
  volume       = {{4}},
  year         = {{2019}},
}

@article{10015,
  author       = {{Dues, Christof and Schmidt, Wolf Gero and Sanna, Simone}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{3850--3859}},
  title        = {{{Water Splitting Reaction at Polar Lithium Niobate Surfaces}}},
  doi          = {{10.1021/acsomega.8b03271}},
  year         = {{2019}},
}

@article{22661,
  author       = {{Kollmann, Fabian and Ramakrishnan, Saminathan and Shen, Boxuan and Grundmeier, Guido and Kostiainen, Mauri A. and Linko, Veikko and Keller, Adrian}},
  issn         = {{2470-1343}},
  journal      = {{ACS Omega}},
  pages        = {{9441--9448}},
  title        = {{{Superstructure-Dependent Loading of DNA Origami Nanostructures with a Groove-Binding Drug}}},
  doi          = {{10.1021/acsomega.8b00934}},
  volume       = {{3}},
  year         = {{2018}},
}