@article{20271,
author = {{Julian, Frei and Biegler, Max and Rethmeier, Michael and Böhne, Christoph and Meschut, Gerson}},
journal = {{Science and Technology of Welding and Joining}},
number = {{7}},
pages = {{624--633}},
publisher = {{Taylor & Francis}},
title = {{{Investigation of liquid metal embrittlement of dual phase steel joints by electro-thermomechanical spot-welding simulation}}},
doi = {{10.1080/13621718.2019.1582203}},
volume = {{24}},
year = {{2019}},
}
@misc{28364,
author = {{Gausemeier, Jürgen}},
isbn = {{978-3-947647-09-5}},
publisher = {{Verlagsschriftenreihe des Heinz Nixdorf Instituts, Paderborn}},
title = {{{Vorausschau und Technologieplanung. 15. Symposium für Vorausschau und Technologieplanung, Heinz Nixdorf Institut, 21. und 22. November 2019}}},
volume = {{390}},
year = {{2019}},
}
@inproceedings{24058,
abstract = {{Embedded systems require a high energy efficiency in combination with an optimized performance. As such, Bit Manipulation Instructions (BMIs) were introduced for x86 and ARMv8 to improve the runtime efficiency and power dissipation of the compiled software for various applications. Though the RISC-V platform is meanwhile widely accepted for embedded systems application, its instruction set architecture (ISA) currently still supports only two basic BMIs.We introduce ten advanced BMIs for the RISC-V ISA and implemented them on Berkeley's Rocket CPU [1], which we synthesized for the Artix-7 FPGA and the TSMC 65nm cell library. Our RISC-V BMI definitions are based on an analysis and combination of existing x86 and ARMv8 BMIs. Our Rocket CPU hardware extensions show that RISC-V BMI extensions have no negative impact on the critical path of the execution pipeline. Our software evaluations show that we can, for example, expect a significant impact for time and power consuming cryptographic applications.}},
author = {{Koppelmann, Bastian and Adelt, Peer and Müller, Wolfgang and Scheytt, Christoph}},
booktitle = {{29th International Symposium on Power and Timing Modeling, Optimization and Simulation (PATMOS)}},
title = {{{RISC-V Extensions for Bit Manipulation Instructions}}},
doi = {{10.1109/PATMOS.2019.8862170}},
year = {{2019}},
}
@inproceedings{24060,
abstract = {{In diesem Artikel stellen wir eine Methode zur nicht-invasiven dynamischen Speicher- und IO-Analyse mit QEMU für sicherheitskritische eingebettete Software für die RISC-V Befehlssatzarchitektur vor. Die Implementierung basiert auf einer Erweiterung des Tiny Code Generator (TCG) des quelloffenen CPU-Emulators QEMU um die dynamische Identifikation von Zugriffen auf Datenspeicher sowie auf an die CPU angeschlossene IO-Geräte. Wir demonstrieren die Funktionalität der Methode anhand eines Versuchsaufbaus, bei dem eine Schließsystemkontrolle mittels serieller UART-Schnittstelle an einen RISC-V-Prozessor angebunden ist. Dieses Szenario zeigt, dass ein unberechtigter Zugriff auf die UART-Schnittstelle frühzeitig aufgedeckt und ein Angriff auf eine Zugangskontrolle somit endeckt werden kann. }},
author = {{Adelt, Peer and Koppelmann, Bastian and Müller, Wolfgang and Scheytt, Christoph}},
booktitle = {{MBMV 2019-22.Workshop Methoden und Beschreibungssprachen zur Modellierung und Verifikation von Schaltungen und Systemen (MBMV 2019)}},
isbn = {{978-3-8007-4945-4}},
title = {{{Analyse sicherheitskritischer Software für RISC-V Prozessoren}}},
year = {{2019}},
}
@inproceedings{24502,
abstract = {{Liquid atomization is expected to be a key process in Flame Spray Pyrolysis, as it determines the primary droplet size and velocity distribution, which represent initial conditions for flame shape and temperature field. A well-defined manipulation of atomization may be achieved by variation of nozzle geometry, injection parameter or fluid properties. However, change of fluid properties, e.g. varying solvents or increasing the precursor concentration, also influences the final particle properties. In this work, the influence of precursor concentration on fluid properties, spray and particle formation in Flame Spray Pyrolysis is experimentally investigated. High-speed shadowgraphy and Phase-Doppler measurements are conducted in a semi-closed combustion chamber with a well-defined burner geometry (SpraySyn burner) that is based on a coaxial atomization principle. By adding precursor to the flammable solvent, resulting spray characteristics, flame shape and appearance are changed in color, shape and mean droplet size distribution. Compared to resulting mean droplet sizes of pure solvent mixtures (D32, 22 μm), mean droplet sizes in the center of the precursor flame at 30 mm above the burner are generally smaller (D32, 18 μm). Persisting high share of small droplets in the droplet size distribution are presented, that presumably origin from an accumulation of metal organic precursor at the droplet surface during combustion, that acts as a diffusive barrier for high volatility solvent and thus reduces droplet evaporation. Sufficiently high above the nozzle exit, increasing the precursor concentration does not affect the radial distribution of mean droplet sizes but leads to increased mean particle sizes. More precursor presumably leads to higher concentrations of prime particles in the flame, thus probability of particle collusion and agglomeration. High-speed imaging at nozzle exit revealed random fluctuations of initial jet diameter, paired with jet axis shifting around 1000 Hz. These superposed fluctuations determine the initial conditions for atomization, induce pulsations in the flame and thus initiate the entire chain of the particle synthesis process.}},
author = {{Bieber, M. and Tischendorf, R. and Reddemann, M. and Schmid, H.-J. and Kneer, R.}},
keywords = {{FSP, nanoparticle synthesis, in situ measurements}},
location = {{Paris}},
publisher = {{ILASS (European Conference on Liquid Atomization and Spray Systems)}},
title = {{{Influence of precursor concentration on spray and particle formation in flame spray pyrolysis}}},
year = {{2019}},
}
@article{24632,
abstract = {{Prerequisite for an efficient cooling energy system is the knowledge and optimal combination of different operating conditions of individual compression and free cooling chillers. The performance of cooling systems depends on their part-load performance and their condensing temperature, which are often not continuously measured. Recorded energy data remain unused, and manufacturers’ data differ from the real performance. For this purpose, manufacturer and real data are combined and continuously adapted to form part-load chiller models. This study applied a predictive optimization algorithm to calculate the optimal operating conditions of multiple chillers. A sprinkler tank offers the opportunity to store cold-water for later utilization. This potential is used to show the load shifting potential of the cooling system by using a variable electricity price as an input variable to the optimization. The set points from the optimization have been continuously adjusted throughout a dynamic simulation. A case study of a plastic processing company evaluates different scenarios against the status quo. Applying an optimal chiller sequencing and charging strategy of a sprinkler tank leads to electrical energy savings of up to 43%. Purchasing electricity on the EPEX SPOT market leads to additional costs savings of up to 17%. The total energy savings highly depend on the weather conditions and the prediction horizon.}},
author = {{Peesel, Ron-Hendrik and Schlosser, Florian and Meschede, Henning and Dunkelberg, Heiko and Walmsley, Timothy}},
issn = {{1996-1073}},
journal = {{Energies}},
title = {{{Optimization of Cooling Utility System with Continuous Self-Learning Performance Models}}},
doi = {{10.3390/en12101926}},
year = {{2019}},
}
@article{24634,
abstract = {{For increased total site heat integration, the optimal sizing and robust operation of a heat recovery loop (HRL) are prerequisites for economic efficiency. However, sizing based on one representative time series, not considering the variability of process streams due to their discontinuous operation, often leads to oversizing. The sensitive evaluation of the performance of an HRL by Monte Carlo (MC) simulation requires sufficient historical data and performance models. Stochastic time series are generated by distribution functions of measured data. With these inputs, one can then model and reliably assess the benefits of installing a new HRL. A key element of the HRL is a stratified heat storage tank. Validation tests of a stratified tank (ST) showed sufficient accuracy with acceptable simulation time for the variable layer height (VLH) multi-node (MN) modelling approach. The results of the MC simulation of the HRL system show only minor yield losses in terms of heat recovery rate (HRR) for smaller tanks. In this way, costs due to oversizing equipment can be reduced by better understanding the energy-capital trade-off.}},
author = {{Schlosser, Florian and Peesel, Ron-Hendrik and Meschede, Henning and Philipp, Matthias and Walmsley, Timothy and Walmsley, Michael and Atkins, Martin}},
issn = {{1996-1073}},
journal = {{Energies}},
title = {{{Design of Robust Total Site Heat Recovery Loops via Monte Carlo Simulation}}},
doi = {{10.3390/en12050930}},
year = {{2019}},
}
@inproceedings{24639,
author = {{Seevers, Jan-Peter and Schlosser, Florian}},
booktitle = {{Chemical Engineering Transactions}},
location = {{Crete}},
pages = {{373--378}},
title = {{{Integration of Heat Pump Storage Systems in Manufacturing Systems via Data Farming and Monte Carlo Simulation}}},
doi = {{10.3303/CET1976063}},
volume = {{76}},
year = {{2019}},
}
@article{25753,
author = {{Schöppner, Volker and Sporkmann, F.}},
issn = {{2053-7174}},
journal = {{Compounding World}},
pages = {{47--56}},
title = {{{Simulation aids compounding success}}},
year = {{2019}},
}
@article{25754,
author = {{Schöppner, Volker and Brüning, Florian}},
issn = {{1618-8357}},
journal = {{WAK Jahresmagazin}},
pages = {{64--67}},
title = {{{Simulation der Feststoffförderung im Einschneckenextruder}}},
year = {{2019}},
}
@inproceedings{25755,
author = {{Moritzer, Elmar and Wittke, M.}},
booktitle = {{77th Annual Technical Conference of the Society of Plastics Engineers (ANTEC)}},
location = {{Detroit (USA)}},
title = {{{Simulation-based Optimization of Advanced Mixing Elements on Single Screw Extruders}}},
year = {{2019}},
}
@inbook{26098,
abstract = {{Since, in the presence of humidity the inter-particle processes are dominated by capillary forces, a fundamental understanding of the water adsorption and the capillary bridge formation is very important. However, the adsorbed water structure and thus the capillary bridge formation is influenced by various parameters like the particle morphology (e.g. particle size, roughness) as well as the surface chemistry (surface energy, adsorbate structure) and therefore needs to be analyzed on a submicroscopic or even molecular basis. A multi-scale approach ranging from experiments on an individual particle level (AFM and liquid bridge simulation) and investigations on small particle ensembles (combined QCM-D/FTIR) up to macroscopic description of bulk behavior is presented in this chapter. In this context, the combined in situ QCM-D/FTIR experiments are bridging the gap between experiments on an individual particle level and macroscopic bulk behavior. Variation of surface chemistry by means of adsorption of functional organic molecules allows for the correlation of macroscopic particle behavior to nanoscopic effects like the presence and structure of adsorbate layers as well as the formation of capillary bridges while keeping the disperse properties constant. Besides extensive experimental work, simulations of capillary bridges formed by condensation from humid air are presented. It is clearly shown that well known approximations which have been introduced for micron-sized particles are not valid any more for nano-scaled particles. The forces between nanoparticles by static liquid bridges and their dependency on particle size, contact angle, humidity and interparticle distance are discussed in detail. Furthermore, capillary forces during separation of particles are studied thoroughly and a constitutive law based on a contact stiffness allows the transfer to DEM simulations of wet powders. Finally, it is demonstrated by comparison to Molecular Dynamics simulations, that the used continuum approach to simulate capillary bridges might even be used down to particle sizes of a few nanometers, if some additional effects are considered correctly.}},
author = {{Schmid, Hans-Joachim and Grundmeier, Guido and Dörmann, Michael and Orive, Alejandro González and de los Arcos, Teresa and Torun, Boray}},
booktitle = {{Particles in Contact}},
title = {{{Understanding and Manipulation of Nanoparticle Contact Forces by Capillary Bridges}}},
doi = {{10.1007/978-3-030-15899-6_2}},
year = {{2019}},
}
@inproceedings{3287,
abstract = {{For optimal placement and orchestration of network services, it is crucial
that their structure and semantics are specified clearly and comprehensively
and are available to an orchestrator. Existing specification approaches are
either ambiguous or miss important aspects regarding the behavior of virtual
network functions (VNFs) forming a service. We propose to formally and
unambiguously specify the behavior of these functions and services using
Queuing Petri Nets (QPNs). QPNs are an established method that allows to
express queuing, synchronization, stochastically distributed processing delays,
and changing traffic volume and characteristics at each VNF. With QPNs,
multiple VNFs can be connected to complete network services in any structure,
even specifying bidirectional network services containing loops.
We discuss how management and orchestration systems can benefit from our
clear and comprehensive specification approach, leading to better placement of
VNFs and improved Quality of Service. Another benefit of formally specifying
network services with QPNs are diverse analysis options, which allow valuable
insights such as the distribution of end-to-end delay. We propose a tool-based
workflow that supports the specification of network services and the automatic
generation of corresponding simulation code to enable an in-depth analysis of
their behavior and performance.}},
author = {{Schneider, Stefan Balthasar and Sharma, Arnab and Karl, Holger and Wehrheim, Heike}},
booktitle = {{2019 IFIP/IEEE International Symposium on Integrated Network Management (IM)}},
location = {{Washington, DC, USA}},
pages = {{116----124}},
publisher = {{IFIP}},
title = {{{Specifying and Analyzing Virtual Network Services Using Queuing Petri Nets}}},
year = {{2019}},
}
@article{27003,
author = {{Perrar, Ines and Schmitting, Sarah and Della Corte, Karen W. and Buyken, Anette and Alexy, Ute}},
issn = {{1436-6207}},
journal = {{European Journal of Nutrition}},
pages = {{1043--1054}},
title = {{{Age and time trends in sugar intake among children and adolescents: results from the DONALD study}}},
doi = {{10.1007/s00394-019-01965-y}},
year = {{2019}},
}
@article{27004,
author = {{Wong, Tommy H. T. and Buyken, Anette and Brand-Miller, Jennie C. and Louie, Jimmy Chun Yu}},
issn = {{1436-6207}},
journal = {{European Journal of Nutrition}},
pages = {{2357--2367}},
title = {{{Is there a soft drink vs. alcohol seesaw? A cross-sectional analysis of dietary data in the Australian Health Survey 2011–12}}},
doi = {{10.1007/s00394-019-02084-4}},
year = {{2019}},
}
@article{27005,
abstract = {{ABSTRACT
Background
There is controversy on the relevance of dietary sugar intake for cardiometabolic health.
Objective
The aim of this network meta-analysis (NMA) was to assess how isocaloric substitutions of dietary sugar with other carbohydrates affect cardiometabolic risk factors, comparing different intervention studies.
Methods
We included randomized controlled trials (RCTs) investigating the isocaloric effect of substituting dietary sugars (fructose, glucose, sucrose) with other sugars or starch on cardiometabolic risk markers, including LDL cholesterol, triacylglycerol (TG), fasting glucose (FG), glycated hemoglobin (HbA1c), insulin resistance (HOMA-IR), uric acid, C-reactive protein (CRP), alanine transaminase (ALT), aspartate transaminase (AST), and liver fat content. To identify the most beneficial intervention for each outcome, random-effects NMA was conducted by calculating pooled mean differences (MDs) with 95% CIs, and by ranking the surface under the cumulative ranking curves (SUCRAs). The certainty of evidence was evaluated using the Confidence In Network Meta-Analysis tool.
Results
Thirty-eight RCTs, including 1383 participants, were identified. A reduction in LDL-cholesterol concentrations was shown for the exchange of sucrose with starch (MD: −0.23 mmol/L; 95% CI: −0.38, −0.07 mmol/L) or fructose with starch (MD: −0.22 mmol/L; 95% CI: −0.39, −0.05 mmol/L; SUCRAstarch: 98%). FG concentrations were also lower for the exchange of sucrose with starch (MD: −0.14 mmol/L; 95% CI: −0.29, 0.01 mmol/L; SUCRAstarch: 91%). Replacing fructose with an equivalent energy amount of glucose reduced HOMA-IR (MD: −0.36; 95% CI: −0.71, −0.02; SUCRAglucose: 74%) and uric acid (MD: −23.77 µmol/L; 95% CI: −44.21, −3.32 µmol/L; SUCRAglucose: 93%). The certainty of evidence was rated very low to moderate. No significant effects were observed for TG, HbA1c, CRP, ALT, and AST.
Conclusions
Our findings indicate that substitution of sucrose and fructose with starch yielded lower LDL cholesterol. Insulin resistance and uric acid concentrations were beneficially affected by replacement of fructose with glucose. Our findings are limited by the very low to moderate certainty of evidence. This review was registered at www.crd.york.ac.uk/prospero as CRD42018080297.
}},
author = {{Schwingshackl, Lukas and Neuenschwander, Manuela and Hoffmann, Georg and Buyken, Anette and Schlesinger, Sabrina}},
issn = {{0002-9165}},
journal = {{The American Journal of Clinical Nutrition}},
title = {{{Dietary sugars and cardiometabolic risk factors: a network meta-analysis on isocaloric substitution interventions}}},
doi = {{10.1093/ajcn/nqz273}},
year = {{2019}},
}
@article{27006,
abstract = {{Trend analyses suggest that free sugar (FS) intake—while still exceeding 10%E—has decreased among German children and adolescents since 2005, yet that intakes may shift from sugars naturally occurring in foods to added sugars as children age. Thus, we analysed time and age trends in FS intake (%E) from food groups among 3–18 year-olds (1985–2016) using 10,761 3-day dietary records from 1312 DONALD participants (660 boys, 652 girls) by use of polynomial mixed-effects regression models. Among girls, FS from sugar & sweets decreased from 1985 to 2016 (linear trend p < 0.0001), but not among boys (p > 0.05). In the total sample, FS intake from juices increased until 2000 and decreased since 2005 (linear, quadratic trend p < 0.0001). FS from sugar sweetened beverages (SSB) decreased non-linearly from 1985 to 2016 (girls: linear, quadratic, cubic trend p < 0.0001; boys: linear, quadratic, cubic trend p < 0.02). Younger children consumed more FS from juices than older ones, who had a higher FS intake from SSB. FS intake from sugar & sweets increased until early adolescence and decreased afterwards. Since sugar & sweets represent the main source of FS intake and the source with the least pronounced decline in intake, public health measures should focus on these products.}},
author = {{Perrar, Ines and Schadow, Alena M. and Schmitting, Sarah and Buyken, Anette and Alexy, Ute}},
issn = {{2072-6643}},
journal = {{Nutrients}},
title = {{{Time and Age Trends in Free Sugar Intake from Food Groups among Children and Adolescents between 1985 and 2016}}},
doi = {{10.3390/nu12010020}},
year = {{2019}},
}
@article{27023,
abstract = {{Abstract
Background
Blood immunoreactive biomarkers, such as C-reactive protein (CRP), and metabolic abnormalities have been associated with schizophrenia. Studies comprehensively and bidirectionally probing possible causal links between such blood constituents and liability to schizophrenia are lacking.
Methods
To disentangle putative causal links between CRP blood levels and schizophrenia in both directions, we conducted multiple univariable Mendelian-randomization (MR) analyses, ranging from fixed-effect to inverse variance-weighted (IVW), weighted-median, MR Egger and generalized summary-data-based Mendelian-randomization (GSMR) models. To prioritize metabolic risk factors for schizophrenia, a novel multivariable approach was applied: multivariable Mendelian-randomization–Bayesian model averaging (MR-BMA).
Results
All forward univariable MR analyses consistently showed that CRP has a protective effect on schizophrenia, whereas reverse MR analyses consistently suggested absent causal effects of schizophrenia liability on CRP blood levels. Using MR-BMA, as the top protective factors for schizophrenia we prioritized leucine and as the prime risk-factor triglycerides in medium very-low-density lipoprotein (VLDL). The five best-performing MR-BMA models provided one additional risk factor: triglycerides in large VLDL; and two additional protective factors: citrate and lactate.
Conclusions
Our results add to a growing body of literature hinting at metabolic changes—in particular of triglycerides—independently of medication status in schizophrenia. We also highlight the absent effects of genetic liability to schizophrenia on CRP levels.
}},
author = {{Lin, Bochao D and Alkema, Anne and Peters, Triinu and Zinkstok, Janneke and Libuda, Lars and Hebebrand, Johannes and Antel, Jochen and Hinney, Anke and Cahn, Wiepke and Adan, Roger and Luykx, Jurjen J}},
issn = {{0300-5771}},
journal = {{International Journal of Epidemiology}},
pages = {{1505--1514}},
title = {{{Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study}}},
doi = {{10.1093/ije/dyz176}},
year = {{2019}},
}
@article{27024,
author = {{Kalhoff, Hermann and Mesch, Christina M. and Stimming, Madlen and Israel, Andreas and Spitzer, Christoph and Beganovic, Latifa and Perez, Rocio Estella and Koletzko, Berthold and Warschburger, Petra and Kersting, Mathilde and Libuda, Lars}},
issn = {{0954-3007}},
journal = {{European Journal of Clinical Nutrition}},
pages = {{682--690}},
title = {{{Effects of LC-PUFA supply via complementary food on infant development—a food based intervention (RCT) embedded in a total diet concept}}},
doi = {{10.1038/s41430-019-0491-0}},
year = {{2019}},
}
@inbook{27379,
author = {{Schlegel-Matthies, Kirsten}},
booktitle = {{Verbraucherbildung: Ein weiter Weg zum mündigen Verbraucher }},
editor = {{Bala, Christian and Buddensiek, Marit and Maier, Petra and Schuldzinski, Wolfgang}},
isbn = {{978-3-86336-924-8 }},
pages = {{41--60}},
publisher = {{Kompetenzzentrum Verbraucherforschung NRW, Verbraucherzentrale Nordrhein-Westfalen e.V.}},
title = {{{Verbraucherbildung als Bildung für Lebensführung}}},
doi = {{10.15501/978-3-86336-924-8_3}},
year = {{2019}},
}