[{"abstract":[{"lang":"eng","text":"Modern companies are nowadays confronted with an increasing demand of multiple products, where they need to perform more flexible every day. Cost-intensive decisions are to be confirmed in short times, in order to minimize risks and secure efficient production programs as well as material flows. Tools for this digital planning via simulation methods are one well established possibility to receive decision support. Nevertheless, the creation of the necessary simulation models is a complicated and error-prone process, where complexity of modeling, validation and verification depends on the used tool and its functionalities. This paper presents implemented concepts for an innovative user support in his tasks of verification and validation of simulation models during the execution of a simulation run. Time-intensive procedures like stopping simulation, parameterization and restarting within the problem analysis are simplified. So the user is able to focus on the real problem solving task."}],"citation":{"bibtex":"@inproceedings{Laroque_Fischer_Dangelmaier_2009, title={Concepts for Model Verification and Validation during Simulation Runtime}, booktitle={European Simulation and Modelling Conference (ESM 2009)}, publisher={EUROSIS-ETI}, author={Laroque, Christoph and Fischer, Matthias and Dangelmaier, Wilhelm}, year={2009} }","ama":"Laroque C, Fischer M, Dangelmaier W. Concepts for Model Verification and Validation during Simulation Runtime. In: <i>European Simulation and Modelling Conference (ESM 2009)</i>. EUROSIS-ETI; 2009.","mla":"Laroque, Christoph, et al. “Concepts for Model Verification and Validation during Simulation Runtime.” <i>European Simulation and Modelling Conference (ESM 2009)</i>, EUROSIS-ETI, 2009.","chicago":"Laroque, Christoph, Matthias Fischer, and Wilhelm Dangelmaier. “Concepts for Model Verification and Validation during Simulation Runtime.” In <i>European Simulation and Modelling Conference (ESM 2009)</i>. EUROSIS-ETI, 2009.","short":"C. Laroque, M. Fischer, W. Dangelmaier, in: European Simulation and Modelling Conference (ESM 2009), EUROSIS-ETI, 2009.","ieee":"C. Laroque, M. Fischer, and W. Dangelmaier, “Concepts for Model Verification and Validation during Simulation Runtime,” in <i>European Simulation and Modelling Conference (ESM 2009)</i>, 2009.","apa":"Laroque, C., Fischer, M., &#38; Dangelmaier, W. (2009). Concepts for Model Verification and Validation during Simulation Runtime. In <i>European Simulation and Modelling Conference (ESM 2009)</i>. EUROSIS-ETI."},"publication":"European Simulation and Modelling Conference (ESM 2009)","department":[{"_id":"63"}],"type":"conference","date_created":"2020-08-24T07:28:23Z","date_updated":"2022-01-06T06:53:26Z","author":[{"last_name":"Laroque","first_name":"Christoph","full_name":"Laroque, Christoph"},{"first_name":"Matthias","last_name":"Fischer","full_name":"Fischer, Matthias","id":"146"},{"full_name":"Dangelmaier, Wilhelm","last_name":"Dangelmaier","first_name":"Wilhelm"}],"year":"2009","title":"Concepts for Model Verification and Validation during Simulation Runtime","status":"public","user_id":"15415","_id":"18138","publisher":"EUROSIS-ETI","language":[{"iso":"eng"}]},{"title":"Modeling obstacles in INET/Mobility framework: motivation, integration, and performance","year":"2009","status":"public","author":[{"full_name":"Lichte, Hermann S.","last_name":"Lichte","first_name":"Hermann S."},{"first_name":"Jannis","last_name":"Weide","full_name":"Weide, Jannis"}],"publication_identifier":{"isbn":["9789639799455"]},"publication_status":"published","date_updated":"2022-01-06T06:53:29Z","publisher":"ICST","_id":"1832","user_id":"15572","doi":"10.4108/icst.simutools2009.5680","publication":"Proceedings of the Second International ICST Conference on Simulation Tools and Techniques","citation":{"short":"H.S. Lichte, J. Weide, in: Proceedings of the Second International ICST Conference on Simulation Tools and Techniques, ICST, 2009.","ama":"Lichte HS, Weide J. Modeling obstacles in INET/Mobility framework: motivation, integration, and performance. In: <i>Proceedings of the Second International ICST Conference on Simulation Tools and Techniques</i>. ICST; 2009. doi:<a href=\"https://doi.org/10.4108/icst.simutools2009.5680\">10.4108/icst.simutools2009.5680</a>","chicago":"Lichte, Hermann S., and Jannis Weide. “Modeling Obstacles in INET/Mobility Framework: Motivation, Integration, and Performance.” In <i>Proceedings of the Second International ICST Conference on Simulation Tools and Techniques</i>. ICST, 2009. <a href=\"https://doi.org/10.4108/icst.simutools2009.5680\">https://doi.org/10.4108/icst.simutools2009.5680</a>.","bibtex":"@inproceedings{Lichte_Weide_2009, title={Modeling obstacles in INET/Mobility framework: motivation, integration, and performance}, DOI={<a href=\"https://doi.org/10.4108/icst.simutools2009.5680\">10.4108/icst.simutools2009.5680</a>}, booktitle={Proceedings of the Second International ICST Conference on Simulation Tools and Techniques}, publisher={ICST}, author={Lichte, Hermann S. and Weide, Jannis}, year={2009} }","apa":"Lichte, H. S., &#38; Weide, J. (2009). Modeling obstacles in INET/Mobility framework: motivation, integration, and performance. In <i>Proceedings of the Second International ICST Conference on Simulation Tools and Techniques</i>. ICST. <a href=\"https://doi.org/10.4108/icst.simutools2009.5680\">https://doi.org/10.4108/icst.simutools2009.5680</a>","mla":"Lichte, Hermann S., and Jannis Weide. “Modeling Obstacles in INET/Mobility Framework: Motivation, Integration, and Performance.” <i>Proceedings of the Second International ICST Conference on Simulation Tools and Techniques</i>, ICST, 2009, doi:<a href=\"https://doi.org/10.4108/icst.simutools2009.5680\">10.4108/icst.simutools2009.5680</a>.","ieee":"H. S. Lichte and J. Weide, “Modeling obstacles in INET/Mobility framework: motivation, integration, and performance,” in <i>Proceedings of the Second International ICST Conference on Simulation Tools and Techniques</i>, 2009."},"date_created":"2018-03-27T12:34:52Z","type":"conference","department":[{"_id":"75"}]},{"date_created":"2017-11-27T10:22:26Z","department":[{"_id":"75"}],"type":"conference","citation":{"mla":"Simon Lichte, Hermann, et al. “Analyzing Space/Capacity Tradeoffs of Cooperative Wireless Networks Using a Probabilistic Model of Interference.” <i>Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009</i>, 2009, pp. 54--62, doi:<a href=\"https://doi.org/10.1145/1641804.1641817\">10.1145/1641804.1641817</a>.","bibtex":"@inproceedings{Simon Lichte_Valentin_Karl_Aad_Widmer_2009, title={Analyzing space/capacity tradeoffs of cooperative wireless networks using a probabilistic model of interference}, DOI={<a href=\"https://doi.org/10.1145/1641804.1641817\">10.1145/1641804.1641817</a>}, booktitle={Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009}, author={Simon Lichte, Hermann and Valentin, Stefan and Karl, Holger and Aad, Imad and Widmer, J.}, year={2009}, pages={54--62} }","ama":"Simon Lichte H, Valentin S, Karl H, Aad I, Widmer J. Analyzing space/capacity tradeoffs of cooperative wireless networks using a probabilistic model of interference. In: <i>Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009</i>. ; 2009:54--62. doi:<a href=\"https://doi.org/10.1145/1641804.1641817\">10.1145/1641804.1641817</a>","ieee":"H. Simon Lichte, S. Valentin, H. Karl, I. Aad, and J. Widmer, “Analyzing space/capacity tradeoffs of cooperative wireless networks using a probabilistic model of interference,” in <i>Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009</i>, 2009, pp. 54--62.","apa":"Simon Lichte, H., Valentin, S., Karl, H., Aad, I., &#38; Widmer, J. (2009). Analyzing space/capacity tradeoffs of cooperative wireless networks using a probabilistic model of interference. In <i>Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009</i> (pp. 54--62). <a href=\"https://doi.org/10.1145/1641804.1641817\">https://doi.org/10.1145/1641804.1641817</a>","chicago":"Simon Lichte, Hermann, Stefan Valentin, Holger Karl, Imad Aad, and J. Widmer. “Analyzing Space/Capacity Tradeoffs of Cooperative Wireless Networks Using a Probabilistic Model of Interference.” In <i>Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009</i>, 54--62, 2009. <a href=\"https://doi.org/10.1145/1641804.1641817\">https://doi.org/10.1145/1641804.1641817</a>.","short":"H. Simon Lichte, S. Valentin, H. Karl, I. Aad, J. Widmer, in: Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009, 2009, pp. 54--62."},"publication":"Proceedings of the 12th International Symposium on Modeling Analysis and Simulation of Wireless and Mobile Systems, MSWiM 2009, Tenerife, Canary Islands, Spain, October 26-19, 2009","_id":"819","page":"54--62","user_id":"15572","doi":"10.1145/1641804.1641817","author":[{"first_name":"Hermann","last_name":"Simon Lichte","full_name":"Simon Lichte, Hermann"},{"full_name":"Valentin, Stefan","last_name":"Valentin","first_name":"Stefan"},{"id":"126","first_name":"Holger","last_name":"Karl","full_name":"Karl, Holger"},{"last_name":"Aad","first_name":"Imad","full_name":"Aad, Imad"},{"full_name":"Widmer, J.","first_name":"J.","last_name":"Widmer"}],"status":"public","title":"Analyzing space/capacity tradeoffs of cooperative wireless networks using a probabilistic model of interference","year":"2009","date_updated":"2022-01-06T07:03:52Z"},{"date_created":"2018-10-10T11:08:18Z","department":[{"_id":"206"}],"type":"journal_article","issue":"12","publication":"Journal of Statistical Computation and Simulation","language":[{"iso":"eng"}],"doi":"10.1080/00949650802352019","author":[{"first_name":"Yuanhua","last_name":"Feng","full_name":"Feng, Yuanhua","id":"20760"},{"last_name":"Heiler","first_name":"Siegfried","full_name":"Heiler, Siegfried"}],"publication_identifier":{"issn":["0094-9655","1563-5163"]},"title":"A simple bootstrap bandwidth selector for local polynomial fitting","year":"2009","intvolume":"        79","date_updated":"2022-01-06T07:01:14Z","publication_status":"published","citation":{"ieee":"Y. Feng and S. Heiler, “A simple bootstrap bandwidth selector for local polynomial fitting,” <i>Journal of Statistical Computation and Simulation</i>, vol. 79, no. 12, pp. 1425–1439, 2009.","apa":"Feng, Y., &#38; Heiler, S. (2009). A simple bootstrap bandwidth selector for local polynomial fitting. <i>Journal of Statistical Computation and Simulation</i>, <i>79</i>(12), 1425–1439. <a href=\"https://doi.org/10.1080/00949650802352019\">https://doi.org/10.1080/00949650802352019</a>","chicago":"Feng, Yuanhua, and Siegfried Heiler. “A Simple Bootstrap Bandwidth Selector for Local Polynomial Fitting.” <i>Journal of Statistical Computation and Simulation</i> 79, no. 12 (2009): 1425–39. <a href=\"https://doi.org/10.1080/00949650802352019\">https://doi.org/10.1080/00949650802352019</a>.","short":"Y. Feng, S. Heiler, Journal of Statistical Computation and Simulation 79 (2009) 1425–1439.","mla":"Feng, Yuanhua, and Siegfried Heiler. “A Simple Bootstrap Bandwidth Selector for Local Polynomial Fitting.” <i>Journal of Statistical Computation and Simulation</i>, vol. 79, no. 12, Informa UK Limited, 2009, pp. 1425–39, doi:<a href=\"https://doi.org/10.1080/00949650802352019\">10.1080/00949650802352019</a>.","bibtex":"@article{Feng_Heiler_2009, title={A simple bootstrap bandwidth selector for local polynomial fitting}, volume={79}, DOI={<a href=\"https://doi.org/10.1080/00949650802352019\">10.1080/00949650802352019</a>}, number={12}, journal={Journal of Statistical Computation and Simulation}, publisher={Informa UK Limited}, author={Feng, Yuanhua and Heiler, Siegfried}, year={2009}, pages={1425–1439} }","ama":"Feng Y, Heiler S. A simple bootstrap bandwidth selector for local polynomial fitting. <i>Journal of Statistical Computation and Simulation</i>. 2009;79(12):1425-1439. doi:<a href=\"https://doi.org/10.1080/00949650802352019\">10.1080/00949650802352019</a>"},"_id":"4608","publisher":"Informa UK Limited","page":"1425-1439","volume":79,"user_id":"10075","status":"public"},{"issue":"07","publication":"Journal of Materials Research","type":"journal_article","department":[{"_id":"15"},{"_id":"230"},{"_id":"287"},{"_id":"35"}],"date_created":"2019-02-04T14:46:14Z","date_updated":"2022-01-06T07:03:39Z","publication_status":"published","intvolume":"        24","title":"Electron energy structure of self-assembled In(Ga)As nanostructures probed by capacitance-voltage spectroscopy and one-dimensional numerical simulation","year":"2009","author":[{"first_name":"Wen","last_name":"Lei","full_name":"Lei, Wen"},{"last_name":"Notthoff","first_name":"Christian","full_name":"Notthoff, Christian"},{"full_name":"Offer, Matthias","last_name":"Offer","first_name":"Matthias"},{"full_name":"Meier, Cedrik","orcid":"https://orcid.org/0000-0002-3787-3572","first_name":"Cedrik","last_name":"Meier","id":"20798"},{"full_name":"Lorke, Axel","last_name":"Lorke","first_name":"Axel"},{"full_name":"Jagadish, Chennupati","last_name":"Jagadish","first_name":"Chennupati"},{"full_name":"Wieck, Andreas D.","first_name":"Andreas D.","last_name":"Wieck"}],"publication_identifier":{"issn":["0884-2914","2044-5326"]},"doi":"10.1557/jmr.2009.0293","language":[{"iso":"eng"}],"citation":{"ieee":"W. Lei <i>et al.</i>, “Electron energy structure of self-assembled In(Ga)As nanostructures probed by capacitance-voltage spectroscopy and one-dimensional numerical simulation,” <i>Journal of Materials Research</i>, vol. 24, no. 07, pp. 2179–2184, 2009.","apa":"Lei, W., Notthoff, C., Offer, M., Meier, C., Lorke, A., Jagadish, C., &#38; Wieck, A. D. (2009). Electron energy structure of self-assembled In(Ga)As nanostructures probed by capacitance-voltage spectroscopy and one-dimensional numerical simulation. <i>Journal of Materials Research</i>, <i>24</i>(07), 2179–2184. <a href=\"https://doi.org/10.1557/jmr.2009.0293\">https://doi.org/10.1557/jmr.2009.0293</a>","short":"W. Lei, C. Notthoff, M. Offer, C. Meier, A. Lorke, C. Jagadish, A.D. Wieck, Journal of Materials Research 24 (2009) 2179–2184.","chicago":"Lei, Wen, Christian Notthoff, Matthias Offer, Cedrik Meier, Axel Lorke, Chennupati Jagadish, and Andreas D. Wieck. “Electron Energy Structure of Self-Assembled In(Ga)As Nanostructures Probed by Capacitance-Voltage Spectroscopy and One-Dimensional Numerical Simulation.” <i>Journal of Materials Research</i> 24, no. 07 (2009): 2179–84. <a href=\"https://doi.org/10.1557/jmr.2009.0293\">https://doi.org/10.1557/jmr.2009.0293</a>.","mla":"Lei, Wen, et al. “Electron Energy Structure of Self-Assembled In(Ga)As Nanostructures Probed by Capacitance-Voltage Spectroscopy and One-Dimensional Numerical Simulation.” <i>Journal of Materials Research</i>, vol. 24, no. 07, Cambridge University Press (CUP), 2009, pp. 2179–84, doi:<a href=\"https://doi.org/10.1557/jmr.2009.0293\">10.1557/jmr.2009.0293</a>.","bibtex":"@article{Lei_Notthoff_Offer_Meier_Lorke_Jagadish_Wieck_2009, title={Electron energy structure of self-assembled In(Ga)As nanostructures probed by capacitance-voltage spectroscopy and one-dimensional numerical simulation}, volume={24}, DOI={<a href=\"https://doi.org/10.1557/jmr.2009.0293\">10.1557/jmr.2009.0293</a>}, number={07}, journal={Journal of Materials Research}, publisher={Cambridge University Press (CUP)}, author={Lei, Wen and Notthoff, Christian and Offer, Matthias and Meier, Cedrik and Lorke, Axel and Jagadish, Chennupati and Wieck, Andreas D.}, year={2009}, pages={2179–2184} }","ama":"Lei W, Notthoff C, Offer M, et al. Electron energy structure of self-assembled In(Ga)As nanostructures probed by capacitance-voltage spectroscopy and one-dimensional numerical simulation. <i>Journal of Materials Research</i>. 2009;24(07):2179-2184. doi:<a href=\"https://doi.org/10.1557/jmr.2009.0293\">10.1557/jmr.2009.0293</a>"},"status":"public","user_id":"20798","volume":24,"page":"2179-2184","_id":"7498","publisher":"Cambridge University Press (CUP)"},{"publication_status":"published","date_updated":"2022-01-06T07:00:33Z","article_type":"original","intvolume":"         8","title":"Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime","year":"2009","author":[{"full_name":"Üpping, J.","last_name":"Üpping","first_name":"J."},{"first_name":"P.T.","last_name":"Miclea","full_name":"Miclea, P.T."},{"full_name":"Wehrspohn, R.B.","last_name":"Wehrspohn","first_name":"R.B."},{"last_name":"Baumgarten","first_name":"T.","full_name":"Baumgarten, T."},{"first_name":"Siegmund","last_name":"Greulich-Weber","full_name":"Greulich-Weber, Siegmund"}],"publication_identifier":{"issn":["1569-4410"]},"doi":"10.1016/j.photonics.2009.11.002","language":[{"iso":"eng"}],"abstract":[{"text":"Three-dimensional (3D) photonic crystal exhibit direction-selective transmission with respect to the center frequency of the stop gap. As a model system, the stop gap of a 3D fcc inverted-opal photonic crystal is studied in the microwave regime in detail using 3D polyamide models. The difference in the direction-selective transmittance between crystals grown in two different high symmetry directions is experimentally shown and compared to numerical simulations.","lang":"eng"}],"publication":"Photonics and Nanostructures - Fundamentals and Applications","issue":"2","type":"journal_article","department":[{"_id":"15"}],"file":[{"date_created":"2018-08-28T12:19:51Z","creator":"hclaudia","success":1,"content_type":"application/pdf","file_id":"4199","date_updated":"2018-08-28T12:19:51Z","relation":"main_file","file_size":310534,"access_level":"closed","file_name":"Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime.pdf"}],"date_created":"2018-08-28T12:19:16Z","has_accepted_license":"1","status":"public","user_id":"55706","ddc":["530"],"volume":8,"page":"102-106","_id":"4198","publisher":"Elsevier BV","file_date_updated":"2018-08-28T12:19:51Z","citation":{"ama":"Üpping J, Miclea PT, Wehrspohn RB, Baumgarten T, Greulich-Weber S. Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime. <i>Photonics and Nanostructures - Fundamentals and Applications</i>. 2009;8(2):102-106. doi:<a href=\"https://doi.org/10.1016/j.photonics.2009.11.002\">10.1016/j.photonics.2009.11.002</a>","bibtex":"@article{Üpping_Miclea_Wehrspohn_Baumgarten_Greulich-Weber_2009, title={Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime}, volume={8}, DOI={<a href=\"https://doi.org/10.1016/j.photonics.2009.11.002\">10.1016/j.photonics.2009.11.002</a>}, number={2}, journal={Photonics and Nanostructures - Fundamentals and Applications}, publisher={Elsevier BV}, author={Üpping, J. and Miclea, P.T. and Wehrspohn, R.B. and Baumgarten, T. and Greulich-Weber, Siegmund}, year={2009}, pages={102–106} }","mla":"Üpping, J., et al. “Direction-Selective Optical Transmission of 3D Fcc Photonic Crystals in the Microwave Regime.” <i>Photonics and Nanostructures - Fundamentals and Applications</i>, vol. 8, no. 2, Elsevier BV, 2009, pp. 102–06, doi:<a href=\"https://doi.org/10.1016/j.photonics.2009.11.002\">10.1016/j.photonics.2009.11.002</a>.","short":"J. Üpping, P.T. Miclea, R.B. Wehrspohn, T. Baumgarten, S. Greulich-Weber, Photonics and Nanostructures - Fundamentals and Applications 8 (2009) 102–106.","chicago":"Üpping, J., P.T. Miclea, R.B. Wehrspohn, T. Baumgarten, and Siegmund Greulich-Weber. “Direction-Selective Optical Transmission of 3D Fcc Photonic Crystals in the Microwave Regime.” <i>Photonics and Nanostructures - Fundamentals and Applications</i> 8, no. 2 (2009): 102–6. <a href=\"https://doi.org/10.1016/j.photonics.2009.11.002\">https://doi.org/10.1016/j.photonics.2009.11.002</a>.","apa":"Üpping, J., Miclea, P. T., Wehrspohn, R. B., Baumgarten, T., &#38; Greulich-Weber, S. (2009). Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime. <i>Photonics and Nanostructures - Fundamentals and Applications</i>, <i>8</i>(2), 102–106. <a href=\"https://doi.org/10.1016/j.photonics.2009.11.002\">https://doi.org/10.1016/j.photonics.2009.11.002</a>","ieee":"J. Üpping, P. T. Miclea, R. B. Wehrspohn, T. Baumgarten, and S. Greulich-Weber, “Direction-selective optical transmission of 3D fcc photonic crystals in the microwave regime,” <i>Photonics and Nanostructures - Fundamentals and Applications</i>, vol. 8, no. 2, pp. 102–106, 2009."}},{"publication_status":"published","date_updated":"2022-01-06T06:52:53Z","status":"public","title":"Local expansion concepts for detecting transport barriers in dynamical systems","year":"2009","publication_identifier":{"issn":["1007-5704"]},"author":[{"last_name":"Padberg","first_name":"Kathrin","full_name":"Padberg, Kathrin"},{"full_name":"Thiere, Bianca","first_name":"Bianca","last_name":"Thiere"},{"full_name":"Preis, Robert","first_name":"Robert","last_name":"Preis"},{"full_name":"Dellnitz, Michael","last_name":"Dellnitz","first_name":"Michael"}],"user_id":"15701","doi":"10.1016/j.cnsns.2009.03.018","page":"4176-4190","language":[{"iso":"eng"}],"_id":"16649","publication":"Communications in Nonlinear Science and Numerical Simulation","citation":{"short":"K. Padberg, B. Thiere, R. Preis, M. Dellnitz, Communications in Nonlinear Science and Numerical Simulation (2009) 4176–4190.","chicago":"Padberg, Kathrin, Bianca Thiere, Robert Preis, and Michael Dellnitz. “Local Expansion Concepts for Detecting Transport Barriers in Dynamical Systems.” <i>Communications in Nonlinear Science and Numerical Simulation</i>, 2009, 4176–90. <a href=\"https://doi.org/10.1016/j.cnsns.2009.03.018\">https://doi.org/10.1016/j.cnsns.2009.03.018</a>.","ieee":"K. Padberg, B. Thiere, R. Preis, and M. Dellnitz, “Local expansion concepts for detecting transport barriers in dynamical systems,” <i>Communications in Nonlinear Science and Numerical Simulation</i>, pp. 4176–4190, 2009.","apa":"Padberg, K., Thiere, B., Preis, R., &#38; Dellnitz, M. (2009). Local expansion concepts for detecting transport barriers in dynamical systems. <i>Communications in Nonlinear Science and Numerical Simulation</i>, 4176–4190. <a href=\"https://doi.org/10.1016/j.cnsns.2009.03.018\">https://doi.org/10.1016/j.cnsns.2009.03.018</a>","bibtex":"@article{Padberg_Thiere_Preis_Dellnitz_2009, title={Local expansion concepts for detecting transport barriers in dynamical systems}, DOI={<a href=\"https://doi.org/10.1016/j.cnsns.2009.03.018\">10.1016/j.cnsns.2009.03.018</a>}, journal={Communications in Nonlinear Science and Numerical Simulation}, author={Padberg, Kathrin and Thiere, Bianca and Preis, Robert and Dellnitz, Michael}, year={2009}, pages={4176–4190} }","ama":"Padberg K, Thiere B, Preis R, Dellnitz M. Local expansion concepts for detecting transport barriers in dynamical systems. <i>Communications in Nonlinear Science and Numerical Simulation</i>. 2009:4176-4190. doi:<a href=\"https://doi.org/10.1016/j.cnsns.2009.03.018\">10.1016/j.cnsns.2009.03.018</a>","mla":"Padberg, Kathrin, et al. “Local Expansion Concepts for Detecting Transport Barriers in Dynamical Systems.” <i>Communications in Nonlinear Science and Numerical Simulation</i>, 2009, pp. 4176–90, doi:<a href=\"https://doi.org/10.1016/j.cnsns.2009.03.018\">10.1016/j.cnsns.2009.03.018</a>."},"type":"journal_article","department":[{"_id":"101"}],"date_created":"2020-04-16T09:11:26Z"},{"author":[{"first_name":"Sven","last_name":"Peschke","full_name":"Peschke, Sven"},{"first_name":"Maik","last_name":"Bevermeier","full_name":"Bevermeier, Maik"},{"last_name":"Haeb-Umbach","first_name":"Reinhold","full_name":"Haeb-Umbach, Reinhold","id":"242"}],"year":"2009","title":"A GPS positioning approach exploiting GSM velocity estimates","status":"public","date_updated":"2022-01-06T06:51:11Z","language":[{"iso":"eng"}],"_id":"11881","page":"195-202","main_file_link":[{"url":"https://groups.uni-paderborn.de/nt/pubs/2009/PeBeHa09-1.pdf","open_access":"1"}],"doi":"10.1109/WPNC.2009.4907827","user_id":"44006","citation":{"bibtex":"@inproceedings{Peschke_Bevermeier_Haeb-Umbach_2009, title={A GPS positioning approach exploiting GSM velocity estimates}, DOI={<a href=\"https://doi.org/10.1109/WPNC.2009.4907827\">10.1109/WPNC.2009.4907827</a>}, booktitle={6th Workshop on Positioning Navigation and Communication (WPNC 2009)}, author={Peschke, Sven and Bevermeier, Maik and Haeb-Umbach, Reinhold}, year={2009}, pages={195–202} }","chicago":"Peschke, Sven, Maik Bevermeier, and Reinhold Haeb-Umbach. “A GPS Positioning Approach Exploiting GSM Velocity Estimates.” In <i>6th Workshop on Positioning Navigation and Communication (WPNC 2009)</i>, 195–202, 2009. <a href=\"https://doi.org/10.1109/WPNC.2009.4907827\">https://doi.org/10.1109/WPNC.2009.4907827</a>.","short":"S. Peschke, M. Bevermeier, R. Haeb-Umbach, in: 6th Workshop on Positioning Navigation and Communication (WPNC 2009), 2009, pp. 195–202.","ama":"Peschke S, Bevermeier M, Haeb-Umbach R. A GPS positioning approach exploiting GSM velocity estimates. In: <i>6th Workshop on Positioning Navigation and Communication (WPNC 2009)</i>. ; 2009:195-202. doi:<a href=\"https://doi.org/10.1109/WPNC.2009.4907827\">10.1109/WPNC.2009.4907827</a>","ieee":"S. Peschke, M. Bevermeier, and R. Haeb-Umbach, “A GPS positioning approach exploiting GSM velocity estimates,” in <i>6th Workshop on Positioning Navigation and Communication (WPNC 2009)</i>, 2009, pp. 195–202.","mla":"Peschke, Sven, et al. “A GPS Positioning Approach Exploiting GSM Velocity Estimates.” <i>6th Workshop on Positioning Navigation and Communication (WPNC 2009)</i>, 2009, pp. 195–202, doi:<a href=\"https://doi.org/10.1109/WPNC.2009.4907827\">10.1109/WPNC.2009.4907827</a>.","apa":"Peschke, S., Bevermeier, M., &#38; Haeb-Umbach, R. (2009). A GPS positioning approach exploiting GSM velocity estimates. In <i>6th Workshop on Positioning Navigation and Communication (WPNC 2009)</i> (pp. 195–202). <a href=\"https://doi.org/10.1109/WPNC.2009.4907827\">https://doi.org/10.1109/WPNC.2009.4907827</a>"},"publication":"6th Workshop on Positioning Navigation and Communication (WPNC 2009)","abstract":[{"text":"A combination of GPS (global positioning system) and INS (inertial navigation system) is known to provide high precision and highly robust vehicle localization. Notably during times when the GPS signal has a poor quality, e.g. due to the lack of a sufficiently large number of visible satellites, the INS, which may consist of a gyroscope and an odometer, will lead to improved positioning accuracy. In this paper we show how velocity information obtained from GSM (global system for mobile communications) signalling, rather than from a tachometer, can be used together with a gyroscope sensor to support localization in the presence of temporarily unavailable GPS data. We propose a sensor fusion system architecture and present simulation results that show the effectiveness of this approach.","lang":"eng"}],"date_created":"2019-07-12T05:30:04Z","oa":"1","department":[{"_id":"54"}],"keyword":["cellular radio","distance measurement","global positioning system","Global Positioning System","global system for mobile communications","GPS positioning approach","GSM velocity","gyroscopes","gyroscope sensor","inertial navigation","inertial navigation system","odometer","sensor fusion system architecture","sensors"],"type":"conference"},{"date_updated":"2022-01-06T06:51:16Z","publication_status":"published","title":"Simulation of Ad Hoc Routing Protocols using OMNeT++","status":"public","year":"2009","publication_identifier":{"issn":["1383-469X","1572-8153"]},"author":[{"full_name":"Sommer, Christoph","first_name":"Christoph","last_name":"Sommer","orcid":"0000-0002-4336-7350","id":"49154"},{"full_name":"Dietrich, Isabel","last_name":"Dietrich","first_name":"Isabel"},{"last_name":"Dressler","first_name":"Falko","full_name":"Dressler, Falko"}],"doi":"10.1007/s11036-009-0174-5","user_id":"49154","page":"786-801","_id":"12060","language":[{"iso":"eng"}],"publication":"Mobile Networks and Applications","citation":{"short":"C. Sommer, I. Dietrich, F. Dressler, Mobile Networks and Applications (2009) 786–801.","chicago":"Sommer, Christoph, Isabel Dietrich, and Falko Dressler. “Simulation of Ad Hoc Routing Protocols Using OMNeT++.” <i>Mobile Networks and Applications</i>, 2009, 786–801. <a href=\"https://doi.org/10.1007/s11036-009-0174-5\">https://doi.org/10.1007/s11036-009-0174-5</a>.","apa":"Sommer, C., Dietrich, I., &#38; Dressler, F. (2009). Simulation of Ad Hoc Routing Protocols using OMNeT++. <i>Mobile Networks and Applications</i>, 786–801. <a href=\"https://doi.org/10.1007/s11036-009-0174-5\">https://doi.org/10.1007/s11036-009-0174-5</a>","ieee":"C. Sommer, I. Dietrich, and F. Dressler, “Simulation of Ad Hoc Routing Protocols using OMNeT++,” <i>Mobile Networks and Applications</i>, pp. 786–801, 2009.","ama":"Sommer C, Dietrich I, Dressler F. Simulation of Ad Hoc Routing Protocols using OMNeT++. <i>Mobile Networks and Applications</i>. 2009:786-801. doi:<a href=\"https://doi.org/10.1007/s11036-009-0174-5\">10.1007/s11036-009-0174-5</a>","bibtex":"@article{Sommer_Dietrich_Dressler_2009, title={Simulation of Ad Hoc Routing Protocols using OMNeT++}, DOI={<a href=\"https://doi.org/10.1007/s11036-009-0174-5\">10.1007/s11036-009-0174-5</a>}, journal={Mobile Networks and Applications}, author={Sommer, Christoph and Dietrich, Isabel and Dressler, Falko}, year={2009}, pages={786–801} }","mla":"Sommer, Christoph, et al. “Simulation of Ad Hoc Routing Protocols Using OMNeT++.” <i>Mobile Networks and Applications</i>, 2009, pp. 786–801, doi:<a href=\"https://doi.org/10.1007/s11036-009-0174-5\">10.1007/s11036-009-0174-5</a>."},"type":"journal_article","department":[{"_id":"589"}],"date_created":"2019-07-18T09:55:21Z"},{"abstract":[{"lang":"eng","text":"In this contribution, possibilities and methods for computer-assisted design of ultrasound transducers are described. These transducers are essential for an ultrasonic sensor design, e.g. for continuous non-invasive determination of quantities that are important in process technology. To achieve technical reliability and robustness, the precise determination of all acoustic properties of the used sensor materials is of great importance. Problem-oriented modeling, numerical simulation, special optimization algorithms and improved methods for the visualization of propagating waves offer new and promising possibilities for developing ultrasonic transducers with enhanced properties."}],"citation":{"short":"B. Henning, J. Rautenberg, C. Unverzagt, A. Schröder, S. Olfert, Journal of Measurement Science and Technology, MST 20 (2009).","chicago":"Henning, Bernd, Jens Rautenberg, Carsten Unverzagt, Andreas Schröder, and Sergei Olfert. “Computer Assisted Design of Transducers for Ultrasonic Sensor Systems.” <i>Journal of Measurement Science and Technology, MST</i> 20, no. 124012 (11pp) (2009).","apa":"Henning, B., Rautenberg, J., Unverzagt, C., Schröder, A., &#38; Olfert, S. (2009). Computer assisted design of transducers for ultrasonic sensor systems. <i>Journal of Measurement Science and Technology, MST</i>, <i>20</i>(124012 (11pp)).","ieee":"B. Henning, J. Rautenberg, C. Unverzagt, A. Schröder, and S. Olfert, “Computer assisted design of transducers for ultrasonic sensor systems,” <i>Journal of Measurement Science and Technology, MST</i>, vol. 20, no. 124012 (11pp), 2009.","ama":"Henning B, Rautenberg J, Unverzagt C, Schröder A, Olfert S. Computer assisted design of transducers for ultrasonic sensor systems. <i>Journal of Measurement Science and Technology, MST</i>. 2009;20(124012 (11pp)).","bibtex":"@article{Henning_Rautenberg_Unverzagt_Schröder_Olfert_2009, title={Computer assisted design of transducers for ultrasonic sensor systems}, volume={20}, number={124012 (11pp)}, journal={Journal of Measurement Science and Technology, MST}, author={Henning, Bernd and Rautenberg, Jens and Unverzagt, Carsten and Schröder, Andreas and Olfert, Sergei}, year={2009} }","mla":"Henning, Bernd, et al. “Computer Assisted Design of Transducers for Ultrasonic Sensor Systems.” <i>Journal of Measurement Science and Technology, MST</i>, vol. 20, no. 124012 (11pp), 2009."},"publication":"Journal of Measurement Science and Technology, MST","issue":"124012 (11pp)","department":[{"_id":"49"}],"type":"journal_article","date_created":"2019-12-04T11:33:28Z","intvolume":"        20","date_updated":"2022-01-06T06:52:19Z","author":[{"last_name":"Henning","first_name":"Bernd","full_name":"Henning, Bernd","id":"213"},{"full_name":"Rautenberg, Jens","last_name":"Rautenberg","first_name":"Jens"},{"first_name":"Carsten","last_name":"Unverzagt","full_name":"Unverzagt, Carsten"},{"full_name":"Schröder, Andreas","first_name":"Andreas","last_name":"Schröder"},{"full_name":"Olfert, Sergei","last_name":"Olfert","first_name":"Sergei"}],"title":"Computer assisted design of transducers for ultrasonic sensor systems","status":"public","year":"2009","volume":20,"user_id":"15911","language":[{"iso":"eng"}],"_id":"15241"},{"date_created":"2022-10-18T10:45:06Z","type":"book_chapter","keyword":["RTOS Modelling","RTOS Simulation","SystemC","Task Scheduling","Interrupt Analysis"],"department":[{"_id":"672"}],"publication":"Hardware Dependent Software - Principles and Practice","abstract":[{"lang":"eng","text":"Today, mobile and embedded real-time systems have to cope with the migration\r\nand allocation of multiple software tasks running on top of a real-time operating\r\nsystem (RTOS) residing on one or several system processors. Each RTOS has to\r\nbe configured towards the individual needs of the application and environment.\r\nFor this, different scheduling strategies and task priorities have to be evaluated in\r\norder to keep execution and response times for a given task set. Abstract RTOS\r\nsimulation is applied to analyze different parameters in early design phases. This\r\nchapter presents a SystemC RTOS library for abstract yet accurate RTOS sim-\r\nulation, supporting modeling of preemption in the presence of prioritized and\r\nnested interrupts. After introducing basic principles of abstract RTOS simula-\r\ntion, we present our SystemC library in detail. Thereafter, we discuss related\r\napproaches and close with applications in electronic automotive systems design\r\nand some evaluations."}],"language":[{"iso":"eng"}],"doi":"10.1007/978-1-4020-9436-1_9","title":"Accurate RTOS Modelling and Analysis with SystemC","year":"2009","author":[{"last_name":"Zabel","first_name":"Henning","full_name":"Zabel, Henning"},{"id":"16243","full_name":"Müller, Wolfgang","last_name":"Müller","first_name":"Wolfgang"},{"last_name":"Gerstlauer","first_name":"Andreas","full_name":"Gerstlauer, Andreas"}],"publication_identifier":{"isbn":["978-1-4020-9435-4"]},"date_updated":"2022-10-18T10:55:55Z","place":"Dordrecht","citation":{"ieee":"H. Zabel, W. Müller, and A. Gerstlauer, “Accurate RTOS Modelling and Analysis with SystemC,” in <i>Hardware Dependent Software - Principles and Practice</i>, W. Ecker, W. Müller, and R. Dömer, Eds. Dordrecht: Springer Verlag, 2009, pp. 233–260.","mla":"Zabel, Henning, et al. “Accurate RTOS Modelling and Analysis with SystemC.” <i>Hardware Dependent Software - Principles and Practice</i>, edited by Wolfgang Ecker et al., Springer Verlag, 2009, pp. 233–60, doi:<a href=\"https://doi.org/10.1007/978-1-4020-9436-1_9\">10.1007/978-1-4020-9436-1_9</a>.","apa":"Zabel, H., Müller, W., &#38; Gerstlauer, A. (2009). Accurate RTOS Modelling and Analysis with SystemC. In W. Ecker, W. Müller, &#38; R. Dömer (Eds.), <i>Hardware Dependent Software - Principles and Practice</i> (pp. 233–260). Springer Verlag. <a href=\"https://doi.org/10.1007/978-1-4020-9436-1_9\">https://doi.org/10.1007/978-1-4020-9436-1_9</a>","bibtex":"@inbook{Zabel_Müller_Gerstlauer_2009, place={Dordrecht}, title={Accurate RTOS Modelling and Analysis with SystemC}, DOI={<a href=\"https://doi.org/10.1007/978-1-4020-9436-1_9\">10.1007/978-1-4020-9436-1_9</a>}, booktitle={Hardware Dependent Software - Principles and Practice}, publisher={Springer Verlag}, author={Zabel, Henning and Müller, Wolfgang and Gerstlauer, Andreas}, editor={Ecker, Wolfgang and Müller, Wolfgang and Dömer, Rainer}, year={2009}, pages={233–260} }","chicago":"Zabel, Henning, Wolfgang Müller, and Andreas Gerstlauer. “Accurate RTOS Modelling and Analysis with SystemC.” In <i>Hardware Dependent Software - Principles and Practice</i>, edited by Wolfgang Ecker, Wolfgang Müller, and Rainer Dömer, 233–60. Dordrecht: Springer Verlag, 2009. <a href=\"https://doi.org/10.1007/978-1-4020-9436-1_9\">https://doi.org/10.1007/978-1-4020-9436-1_9</a>.","ama":"Zabel H, Müller W, Gerstlauer A. Accurate RTOS Modelling and Analysis with SystemC. In: Ecker W, Müller W, Dömer R, eds. <i>Hardware Dependent Software - Principles and Practice</i>. Springer Verlag; 2009:233-260. doi:<a href=\"https://doi.org/10.1007/978-1-4020-9436-1_9\">10.1007/978-1-4020-9436-1_9</a>","short":"H. Zabel, W. Müller, A. Gerstlauer, in: W. Ecker, W. Müller, R. Dömer (Eds.), Hardware Dependent Software - Principles and Practice, Springer Verlag, Dordrecht, 2009, pp. 233–260."},"page":"233-260","_id":"33813","publisher":"Springer Verlag","user_id":"5786","editor":[{"last_name":"Ecker","first_name":"Wolfgang","full_name":"Ecker, Wolfgang"},{"full_name":"Müller, Wolfgang","last_name":"Müller","first_name":"Wolfgang"},{"first_name":"Rainer","last_name":"Dömer","full_name":"Dömer, Rainer"}],"status":"public"},{"date_created":"2023-01-11T11:29:25Z","type":"journal_article","department":[{"_id":"35"},{"_id":"17"},{"_id":"22"},{"_id":"396"}],"issue":"2","publication":"Haushalt & Bildung","citation":{"ama":"Schlegel-Matthies K, Methfessel B, Quellmalz K. Soziale Platzierung: Weder Geld noch Bildung allein entscheiden. <i>Haushalt &#38; Bildung</i>. 2009;86(2):25-27.","bibtex":"@article{Schlegel-Matthies_Methfessel_Quellmalz_2009, title={Soziale Platzierung: Weder Geld noch Bildung allein entscheiden}, volume={86}, number={2}, journal={Haushalt &#38; Bildung}, publisher={Schneider-Verlag}, author={Schlegel-Matthies, Kirsten and Methfessel, Barbara and Quellmalz, Kirsten}, year={2009}, pages={25–27} }","mla":"Schlegel-Matthies, Kirsten, et al. “Soziale Platzierung: Weder Geld noch Bildung allein entscheiden.” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, Schneider-Verlag, 2009, pp. 25–27.","chicago":"Schlegel-Matthies, Kirsten, Barbara Methfessel, and Kirsten Quellmalz. “Soziale Platzierung: Weder Geld noch Bildung allein entscheiden.” <i>Haushalt &#38; Bildung</i> 86, no. 2 (2009): 25–27.","short":"K. Schlegel-Matthies, B. Methfessel, K. Quellmalz, Haushalt &#38; Bildung 86 (2009) 25–27.","apa":"Schlegel-Matthies, K., Methfessel, B., &#38; Quellmalz, K. (2009). Soziale Platzierung: Weder Geld noch Bildung allein entscheiden. <i>Haushalt &#38; Bildung</i>, <i>86</i>(2), 25–27.","ieee":"K. Schlegel-Matthies, B. Methfessel, and K. Quellmalz, “Soziale Platzierung: Weder Geld noch Bildung allein entscheiden,” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, pp. 25–27, 2009."},"page":"25-27","language":[{"iso":"ger"}],"_id":"36056","publisher":"Schneider-Verlag","user_id":"459","volume":86,"year":"2009","status":"public","title":"Soziale Platzierung: Weder Geld noch Bildung allein entscheiden","publication_identifier":{"issn":["0342-5088"]},"author":[{"id":"459","first_name":"Kirsten","last_name":"Schlegel-Matthies","full_name":"Schlegel-Matthies, Kirsten"},{"full_name":"Methfessel, Barbara","last_name":"Methfessel","first_name":"Barbara"},{"first_name":"Kirsten","last_name":"Quellmalz","full_name":"Quellmalz, Kirsten"}],"publication_status":"published","date_updated":"2023-01-11T11:29:54Z","intvolume":"        86"},{"page":"15-20","publisher":"Schneider-Verlag","_id":"36052","language":[{"iso":"ger"}],"user_id":"459","volume":86,"year":"2009","title":"Geld – zentraler Schlüssel für gesellschaftliche Teilhabe","status":"public","author":[{"id":"459","last_name":"Schlegel-Matthies","first_name":"Kirsten","full_name":"Schlegel-Matthies, Kirsten"},{"full_name":"Methfessel, Barbara","first_name":"Barbara","last_name":"Methfessel"}],"publication_identifier":{"issn":["0342-5088"]},"date_updated":"2023-01-11T11:29:56Z","publication_status":"published","intvolume":"        86","date_created":"2023-01-11T11:27:00Z","type":"journal_article","department":[{"_id":"35"},{"_id":"17"},{"_id":"22"},{"_id":"396"}],"publication":"Haushalt & Bildung","issue":"2","citation":{"apa":"Schlegel-Matthies, K., &#38; Methfessel, B. (2009). Geld – zentraler Schlüssel für gesellschaftliche Teilhabe. <i>Haushalt &#38; Bildung</i>, <i>86</i>(2), 15–20.","ieee":"K. Schlegel-Matthies and B. Methfessel, “Geld – zentraler Schlüssel für gesellschaftliche Teilhabe,” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, pp. 15–20, 2009.","short":"K. Schlegel-Matthies, B. Methfessel, Haushalt &#38; Bildung 86 (2009) 15–20.","chicago":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Geld – zentraler Schlüssel für gesellschaftliche Teilhabe.” <i>Haushalt &#38; Bildung</i> 86, no. 2 (2009): 15–20.","mla":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Geld – zentraler Schlüssel für gesellschaftliche Teilhabe.” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, Schneider-Verlag, 2009, pp. 15–20.","ama":"Schlegel-Matthies K, Methfessel B. Geld – zentraler Schlüssel für gesellschaftliche Teilhabe. <i>Haushalt &#38; Bildung</i>. 2009;86(2):15-20.","bibtex":"@article{Schlegel-Matthies_Methfessel_2009, title={Geld – zentraler Schlüssel für gesellschaftliche Teilhabe}, volume={86}, number={2}, journal={Haushalt &#38; Bildung}, publisher={Schneider-Verlag}, author={Schlegel-Matthies, Kirsten and Methfessel, Barbara}, year={2009}, pages={15–20} }"}},{"publication":"Haushalt & Bildung","issue":"2","citation":{"mla":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität.” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, 2009, pp. 21–24.","ama":"Schlegel-Matthies K, Methfessel B. Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität. <i>Haushalt &#38; Bildung</i>. 2009;86(2):21-24.","bibtex":"@article{Schlegel-Matthies_Methfessel_2009, title={Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität}, volume={86}, number={2}, journal={Haushalt &#38; Bildung}, author={Schlegel-Matthies, Kirsten and Methfessel, Barbara}, year={2009}, pages={21–24} }","apa":"Schlegel-Matthies, K., &#38; Methfessel, B. (2009). Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität. <i>Haushalt &#38; Bildung</i>, <i>86</i>(2), 21–24.","ieee":"K. Schlegel-Matthies and B. Methfessel, “Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität,” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, pp. 21–24, 2009.","chicago":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität.” <i>Haushalt &#38; Bildung</i> 86, no. 2 (2009): 21–24.","short":"K. Schlegel-Matthies, B. Methfessel, Haushalt &#38; Bildung 86 (2009) 21–24."},"type":"journal_article","department":[{"_id":"35"},{"_id":"17"},{"_id":"22"},{"_id":"396"}],"date_created":"2023-01-11T11:28:16Z","date_updated":"2023-01-11T11:30:00Z","publication_status":"published","intvolume":"        86","status":"public","year":"2009","title":"Ressourcen – Vielfalt, Zusammenwirken und Lebensqualität","publication_identifier":{"issn":["0342-5088"]},"author":[{"full_name":"Schlegel-Matthies, Kirsten","first_name":"Kirsten","last_name":"Schlegel-Matthies","id":"459"},{"full_name":"Methfessel, Barbara","last_name":"Methfessel","first_name":"Barbara"}],"user_id":"459","volume":86,"page":"21-24","language":[{"iso":"ger"}],"_id":"36054"},{"date_created":"2023-01-11T11:17:23Z","department":[{"_id":"35"},{"_id":"17"},{"_id":"22"},{"_id":"396"}],"type":"journal_article","citation":{"short":"K. Schlegel-Matthies, Haushalt &#38; Bildung 86 (2009) 2.","chicago":"Schlegel-Matthies, Kirsten. “Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten.” <i>Haushalt &#38; Bildung</i> 86, no. 2 (2009): 2.","ieee":"K. Schlegel-Matthies, “Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten,” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, p. 2, 2009.","apa":"Schlegel-Matthies, K. (2009). Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten. <i>Haushalt &#38; Bildung</i>, <i>86</i>(2), 2.","bibtex":"@article{Schlegel-Matthies_2009, title={Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten}, volume={86}, number={2}, journal={Haushalt &#38; Bildung}, publisher={Schneider-Verlag}, author={Schlegel-Matthies, Kirsten}, year={2009}, pages={2} }","ama":"Schlegel-Matthies K. Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten. <i>Haushalt &#38; Bildung</i>. 2009;86(2):2.","mla":"Schlegel-Matthies, Kirsten. “Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten.” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, Schneider-Verlag, 2009, p. 2."},"issue":"2","publication":"Haushalt & Bildung","_id":"36044","language":[{"iso":"ger"}],"publisher":"Schneider-Verlag","page":"2","volume":86,"user_id":"459","publication_identifier":{"issn":["0342-5088"]},"author":[{"id":"459","full_name":"Schlegel-Matthies, Kirsten","first_name":"Kirsten","last_name":"Schlegel-Matthies"}],"status":"public","year":"2009","title":"Ressourcen – Voraussetzung für Teilhabe- und Gestaltungsmöglichkeiten","intvolume":"        86","date_updated":"2023-01-11T11:30:31Z","publication_status":"published"},{"status":"public","title":"Ressourcen im Rahmen des Haushaltshandelns","year":"2009","publication_identifier":{"issn":["0342-5088"]},"author":[{"first_name":"Kirsten","last_name":"Schlegel-Matthies","full_name":"Schlegel-Matthies, Kirsten","id":"459"},{"first_name":"Barbara","last_name":"Methfessel","full_name":"Methfessel, Barbara"}],"publication_status":"published","date_updated":"2023-01-11T11:30:27Z","intvolume":"        86","page":"3-4","language":[{"iso":"ger"}],"_id":"36049","user_id":"459","volume":86,"publication":"Haushalt & Bildung","issue":"2","citation":{"ama":"Schlegel-Matthies K, Methfessel B. Ressourcen im Rahmen des Haushaltshandelns. <i>Haushalt &#38; Bildung</i>. 2009;86(2):3-4.","bibtex":"@article{Schlegel-Matthies_Methfessel_2009, title={Ressourcen im Rahmen des Haushaltshandelns}, volume={86}, number={2}, journal={Haushalt &#38; Bildung}, author={Schlegel-Matthies, Kirsten and Methfessel, Barbara}, year={2009}, pages={3–4} }","mla":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Ressourcen im Rahmen des Haushaltshandelns.” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, 2009, pp. 3–4.","chicago":"Schlegel-Matthies, Kirsten, and Barbara Methfessel. “Ressourcen im Rahmen des Haushaltshandelns.” <i>Haushalt &#38; Bildung</i> 86, no. 2 (2009): 3–4.","short":"K. Schlegel-Matthies, B. Methfessel, Haushalt &#38; Bildung 86 (2009) 3–4.","apa":"Schlegel-Matthies, K., &#38; Methfessel, B. (2009). Ressourcen im Rahmen des Haushaltshandelns. <i>Haushalt &#38; Bildung</i>, <i>86</i>(2), 3–4.","ieee":"K. Schlegel-Matthies and B. Methfessel, “Ressourcen im Rahmen des Haushaltshandelns,” <i>Haushalt &#38; Bildung</i>, vol. 86, no. 2, pp. 3–4, 2009."},"date_created":"2023-01-11T11:24:25Z","type":"journal_article","department":[{"_id":"35"},{"_id":"17"},{"_id":"22"},{"_id":"396"}]},{"date_created":"2024-06-30T13:46:31Z","type":"journal_article","department":[{"_id":"35"},{"_id":"22"}],"issue":"2","publication":"Journal of the American Society of Nephrology","citation":{"ama":"Svenningsen P, Bistrup C, Friis UG, et al. Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel. <i>Journal of the American Society of Nephrology</i>. 2009;20(2):299–310. doi:<a href=\"https://doi.org/10.1681/asn.2008040364\">10.1681/asn.2008040364</a>","bibtex":"@article{Svenningsen_Bistrup_Friis_Bertog_Haerteis_Krueger_Stubbe_Jensen_Thiesson_Uhrenholt_et al._2009, title={Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel}, volume={20}, DOI={<a href=\"https://doi.org/10.1681/asn.2008040364\">10.1681/asn.2008040364</a>}, number={2}, journal={Journal of the American Society of Nephrology}, publisher={Ovid Technologies (Wolters Kluwer Health)}, author={Svenningsen, Per and Bistrup, Claus and Friis, Ulla G. and Bertog, Marko and Haerteis, Silke and Krueger, Bettina and Stubbe, Jane and Jensen, Ole Nørregaard and Thiesson, Helle C. and Uhrenholt, Torben R. and et al.}, year={2009}, pages={299–310} }","mla":"Svenningsen, Per, et al. “Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel.” <i>Journal of the American Society of Nephrology</i>, vol. 20, no. 2, Ovid Technologies (Wolters Kluwer Health), 2009, pp. 299–310, doi:<a href=\"https://doi.org/10.1681/asn.2008040364\">10.1681/asn.2008040364</a>.","chicago":"Svenningsen, Per, Claus Bistrup, Ulla G. Friis, Marko Bertog, Silke Haerteis, Bettina Krueger, Jane Stubbe, et al. “Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel.” <i>Journal of the American Society of Nephrology</i> 20, no. 2 (2009): 299–310. <a href=\"https://doi.org/10.1681/asn.2008040364\">https://doi.org/10.1681/asn.2008040364</a>.","short":"P. Svenningsen, C. Bistrup, U.G. Friis, M. Bertog, S. Haerteis, B. Krueger, J. Stubbe, O.N. Jensen, H.C. Thiesson, T.R. Uhrenholt, B. Jespersen, B.L. Jensen, C. Korbmacher, O. Skøtt, Journal of the American Society of Nephrology 20 (2009) 299–310.","apa":"Svenningsen, P., Bistrup, C., Friis, U. G., Bertog, M., Haerteis, S., Krueger, B., Stubbe, J., Jensen, O. N., Thiesson, H. C., Uhrenholt, T. R., Jespersen, B., Jensen, B. L., Korbmacher, C., &#38; Skøtt, O. (2009). Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel. <i>Journal of the American Society of Nephrology</i>, <i>20</i>(2), 299–310. <a href=\"https://doi.org/10.1681/asn.2008040364\">https://doi.org/10.1681/asn.2008040364</a>","ieee":"P. Svenningsen <i>et al.</i>, “Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel,” <i>Journal of the American Society of Nephrology</i>, vol. 20, no. 2, pp. 299–310, 2009, doi: <a href=\"https://doi.org/10.1681/asn.2008040364\">10.1681/asn.2008040364</a>."},"abstract":[{"lang":"eng","text":"Proteinuria and increased renal reabsorption of NaCl characterize the nephrotic syndrome. Here, we show that protein-rich urine from nephrotic rats and from patients with nephrotic syndrome activate the epithelial sodium channel (ENaC) in cultured M-1 mouse collecting duct cells and in Xenopus laevis oocytes heterologously expressing ENaC. The activation depended on urinary serine protease activity. We identified plasmin as a urinary serine protease by matrix-assisted laser desorption/ionization time of-flight mass spectrometry. Purified plasmin activated ENaC currents, and inhibitors of plasmin abolished urinary protease activity and the ability to activate ENaC. In nephrotic syndrome, tubular urokinase-type plasminogen activator likely converts filtered plasminogen to plasmin. Consistent with this, the combined application of urokinase-type plasminogen activator and plasminogen stimulated amiloride-sensitive transepithelial sodium transport in M-1 cells and increased amiloride-sensitive whole-cell currents in Xenopus laevis oocytes heterologously expressing ENaC. Activation of ENaC by plasmin involved cleavage and release of an inhibitory peptide from the ENaC gamma subunit ectodomain. These data suggest that a defective glomerular filtration barrier allows passage of proteolytic enzymes that have the ability to activate ENaC."}],"page":"299–310","_id":"54931","publisher":"Ovid Technologies (Wolters Kluwer Health)","language":[{"iso":"eng"}],"doi":"10.1681/asn.2008040364","user_id":"49428","volume":20,"status":"public","year":"2009","title":"Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel","author":[{"full_name":"Svenningsen, Per","first_name":"Per","last_name":"Svenningsen"},{"first_name":"Claus","last_name":"Bistrup","full_name":"Bistrup, Claus"},{"first_name":"Ulla G.","last_name":"Friis","full_name":"Friis, Ulla G."},{"full_name":"Bertog, Marko","last_name":"Bertog","first_name":"Marko"},{"first_name":"Silke","last_name":"Haerteis","full_name":"Haerteis, Silke"},{"full_name":"Krueger, Bettina","first_name":"Bettina","orcid":"0000-0001-5351-1785","last_name":"Krueger","id":"49428"},{"first_name":"Jane","last_name":"Stubbe","full_name":"Stubbe, Jane"},{"full_name":"Jensen, Ole Nørregaard","first_name":"Ole Nørregaard","last_name":"Jensen"},{"first_name":"Helle C.","last_name":"Thiesson","full_name":"Thiesson, Helle C."},{"full_name":"Uhrenholt, Torben R.","first_name":"Torben R.","last_name":"Uhrenholt"},{"full_name":"Jespersen, Bente","last_name":"Jespersen","first_name":"Bente"},{"full_name":"Jensen, Boye L.","first_name":"Boye L.","last_name":"Jensen"},{"full_name":"Korbmacher, Christoph","last_name":"Korbmacher","first_name":"Christoph"},{"last_name":"Skøtt","first_name":"Ole","full_name":"Skøtt, Ole"}],"date_updated":"2024-06-30T13:46:44Z","intvolume":"        20"},{"date_created":"2024-06-30T13:47:10Z","type":"journal_article","department":[{"_id":"35"},{"_id":"22"}],"issue":"2","publication":"Molecular Cancer Research","citation":{"bibtex":"@article{Samarin_Rehm_Krueger_Waschke_Goppelt-Struebe_2009, title={Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4}, volume={7}, DOI={<a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">10.1158/1541-7786.mcr-08-0292</a>}, number={2}, journal={Molecular Cancer Research}, publisher={American Association for Cancer Research (AACR)}, author={Samarin, Jana and Rehm, Margot and Krueger, Bettina and Waschke, Jens and Goppelt-Struebe, Margarete}, year={2009}, pages={180–188} }","ama":"Samarin J, Rehm M, Krueger B, Waschke J, Goppelt-Struebe M. Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4. <i>Molecular Cancer Research</i>. 2009;7(2):180–188. doi:<a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">10.1158/1541-7786.mcr-08-0292</a>","mla":"Samarin, Jana, et al. “Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4.” <i>Molecular Cancer Research</i>, vol. 7, no. 2, American Association for Cancer Research (AACR), 2009, pp. 180–188, doi:<a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">10.1158/1541-7786.mcr-08-0292</a>.","chicago":"Samarin, Jana, Margot Rehm, Bettina Krueger, Jens Waschke, and Margarete Goppelt-Struebe. “Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4.” <i>Molecular Cancer Research</i> 7, no. 2 (2009): 180–188. <a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">https://doi.org/10.1158/1541-7786.mcr-08-0292</a>.","short":"J. Samarin, M. Rehm, B. Krueger, J. Waschke, M. Goppelt-Struebe, Molecular Cancer Research 7 (2009) 180–188.","ieee":"J. Samarin, M. Rehm, B. Krueger, J. Waschke, and M. Goppelt-Struebe, “Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4,” <i>Molecular Cancer Research</i>, vol. 7, no. 2, pp. 180–188, 2009, doi: <a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">10.1158/1541-7786.mcr-08-0292</a>.","apa":"Samarin, J., Rehm, M., Krueger, B., Waschke, J., &#38; Goppelt-Struebe, M. (2009). Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4. <i>Molecular Cancer Research</i>, <i>7</i>(2), 180–188. <a href=\"https://doi.org/10.1158/1541-7786.mcr-08-0292\">https://doi.org/10.1158/1541-7786.mcr-08-0292</a>"},"abstract":[{"lang":"eng","text":"Incubation of microvascular endothelial cells with combretastatin A-4 phosphate (CA-4P), a microtubule-destabilizing compound that preferentially targets tumor vessels, altered cell morphology and induced scattering of Golgi stacks. Concomitantly, CA-4P up-regulated connective tissue growth factor (CTGF/CCN2), a pleiotropic factor with antiangiogenic properties. In contrast to the effects of other microtubule-targeting agents such as colchicine or nocodazole, up-regulation of CTGF was only detectable in sparse cells, which were not embedded in a cell monolayer. Furthermore, CA-4P induced CTGF expression in endothelial cells, forming tube-like structures on basement membrane gels. Up-regulation of CTGF by CA-4P was dependent on Rho kinase signaling and was increased when p42/44 mitogen-activated protein kinase was inhibited. Additionally, FoxO transcription factors were identified as potent regulators of CTGF expression in endothelial cells. Activation of FoxO transcription factors by inhibition of phosphatidylinositol 3-kinase/AKT signaling resulted in a synergistic increase in CA-4P-mediated CTGF induction. CA-4P-mediated expression of CTGF was thus potentiated by the inhibition of kinase pathways, which are targets of novel antineoplastic drugs. Up-regulation of CTGF by low concentrations of CA-4P may thus occur in newly formed tumor vessels and contribute to the microvessel destabilization and antiangiogenic effects of CA-4P observed in vivo."}],"page":"180–188","publisher":"American Association for Cancer Research (AACR)","_id":"54932","language":[{"iso":"eng"}],"doi":"10.1158/1541-7786.mcr-08-0292","user_id":"49428","volume":7,"status":"public","title":"Up-Regulation of Connective Tissue Growth Factor in Endothelial Cells by the Microtubule-Destabilizing Agent Combretastatin A-4","year":"2009","author":[{"full_name":"Samarin, Jana","last_name":"Samarin","first_name":"Jana"},{"full_name":"Rehm, Margot","first_name":"Margot","last_name":"Rehm"},{"id":"49428","full_name":"Krueger, Bettina","orcid":"0000-0001-5351-1785","first_name":"Bettina","last_name":"Krueger"},{"full_name":"Waschke, Jens","first_name":"Jens","last_name":"Waschke"},{"last_name":"Goppelt-Struebe","first_name":"Margarete","full_name":"Goppelt-Struebe, Margarete"}],"date_updated":"2024-06-30T13:47:22Z","intvolume":"         7"},{"department":[{"_id":"35"},{"_id":"22"}],"type":"journal_article","date_created":"2024-06-30T13:58:07Z","abstract":[{"lang":"eng","text":"The epithelial sodium channel (ENaC) is probably a heterotrimer with three well characterized subunits (alphabetagamma). In humans an additional delta-subunit (delta-hENaC) exists but little is known about its function. Using the Xenopus laevis oocyte expression system, we compared the functional properties of alphabetagamma- and deltabetagamma-hENaC and investigated whether deltabetagamma-hENaC can be proteolytically activated. The amiloride-sensitive ENaC whole-cell current (DeltaI(ami)) was about 11-fold larger in oocytes expressing deltabetagamma-hENaC than in oocytes expressing alphabetagamma-hENaC. The 2-fold larger single-channel Na(+) conductance of deltabetagamma-hENaC cannot explain this difference. Using a chemiluminescence assay, we demonstrated that an increased channel surface expression is also not the cause. Thus, overall channel activity of deltabetagamma-hENaC must be higher than that of alphabetagamma-hENaC. Experiments exploiting the properties of the known betaS520C mutant ENaC confirmed this conclusion. Moreover, chymotrypsin had a reduced stimulatory effect on deltabetagamma-hENaC whole-cell currents compared with its effect on alphabetagamma-hENaC whole-cell currents (2-fold versus 5-fold). This suggests that the cell surface pool of so-called near-silent channels that can be proteolytically activated is smaller for deltabetagamma-hENaC than for alphabetagamma-hENaC. Proteolytic activation of deltabetagamma-hENaC was associated with the appearance of a delta-hENaC cleavage product at the cell surface. Finally, we demonstrated that a short inhibitory 13-mer peptide corresponding to a region of the extracellular loop of human alpha-ENaC inhibited DeltaI(ami) in oocytes expressing alphabetagamma-hENaC but not in those expressing deltabetagamma-hENaC. We conclude that the delta-subunit of ENaC alters proteolytic channel activation and enhances base-line channel activity."}],"citation":{"ieee":"S. Haerteis, B. Krueger, C. Korbmacher, and R. Rauh, “The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation,” <i>Journal of Biological Chemistry</i>, vol. 284, no. 42, pp. 29024–29040, 2009, doi: <a href=\"https://doi.org/10.1074/jbc.m109.018945\">10.1074/jbc.m109.018945</a>.","apa":"Haerteis, S., Krueger, B., Korbmacher, C., &#38; Rauh, R. (2009). The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation. <i>Journal of Biological Chemistry</i>, <i>284</i>(42), 29024–29040. <a href=\"https://doi.org/10.1074/jbc.m109.018945\">https://doi.org/10.1074/jbc.m109.018945</a>","short":"S. Haerteis, B. Krueger, C. Korbmacher, R. Rauh, Journal of Biological Chemistry 284 (2009) 29024–29040.","chicago":"Haerteis, Silke, Bettina Krueger, Christoph Korbmacher, and Robert Rauh. “The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation.” <i>Journal of Biological Chemistry</i> 284, no. 42 (2009): 29024–29040. <a href=\"https://doi.org/10.1074/jbc.m109.018945\">https://doi.org/10.1074/jbc.m109.018945</a>.","mla":"Haerteis, Silke, et al. “The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation.” <i>Journal of Biological Chemistry</i>, vol. 284, no. 42, American Society for Biochemistry and Molecular Biology, 2009, pp. 29024–29040, doi:<a href=\"https://doi.org/10.1074/jbc.m109.018945\">10.1074/jbc.m109.018945</a>.","bibtex":"@article{Haerteis_Krueger_Korbmacher_Rauh_2009, title={The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation}, volume={284}, DOI={<a href=\"https://doi.org/10.1074/jbc.m109.018945\">10.1074/jbc.m109.018945</a>}, number={42}, journal={Journal of Biological Chemistry}, publisher={American Society for Biochemistry and Molecular Biology}, author={Haerteis, Silke and Krueger, Bettina and Korbmacher, Christoph and Rauh, Robert}, year={2009}, pages={29024–29040} }","ama":"Haerteis S, Krueger B, Korbmacher C, Rauh R. The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation. <i>Journal of Biological Chemistry</i>. 2009;284(42):29024–29040. doi:<a href=\"https://doi.org/10.1074/jbc.m109.018945\">10.1074/jbc.m109.018945</a>"},"issue":"42","publication":"Journal of Biological Chemistry","volume":284,"user_id":"49428","doi":"10.1074/jbc.m109.018945","language":[{"iso":"eng"}],"_id":"54944","publisher":"American Society for Biochemistry and Molecular Biology","page":"29024–29040","intvolume":"       284","date_updated":"2024-06-30T13:58:15Z","author":[{"full_name":"Haerteis, Silke","first_name":"Silke","last_name":"Haerteis"},{"full_name":"Krueger, Bettina","orcid":"0000-0001-5351-1785","last_name":"Krueger","first_name":"Bettina","id":"49428"},{"first_name":"Christoph","last_name":"Korbmacher","full_name":"Korbmacher, Christoph"},{"full_name":"Rauh, Robert","last_name":"Rauh","first_name":"Robert"}],"title":"The $\\delta$-Subunit of the Epithelial Sodium Channel (ENaC) Enhances Channel Activity and Alters Proteolytic ENaC Activation","year":"2009","status":"public"},{"author":[{"last_name":"Krueger","first_name":"Bettina","orcid":"0000-0001-5351-1785","full_name":"Krueger, Bettina","id":"49428"},{"full_name":"Haerteis, Silke","last_name":"Haerteis","first_name":"Silke"},{"full_name":"Yang, Limin","first_name":"Limin","last_name":"Yang"},{"last_name":"Hartner","first_name":"Andrea","full_name":"Hartner, Andrea"},{"first_name":"Robert","last_name":"Rauh","full_name":"Rauh, Robert"},{"first_name":"Christoph","last_name":"Korbmacher","full_name":"Korbmacher, Christoph"},{"first_name":"Alexei","last_name":"Diakov","full_name":"Diakov, Alexei"}],"status":"public","year":"2009","title":"Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1","intvolume":"        24","date_updated":"2024-06-30T13:52:27Z","_id":"54938","publisher":"S. Karger AG","language":[{"iso":"eng"}],"page":"605–618","volume":24,"user_id":"49428","doi":"10.1159/000257516","citation":{"short":"B. Krueger, S. Haerteis, L. Yang, A. Hartner, R. Rauh, C. Korbmacher, A. Diakov, Cellular Physiology and Biochemistry 24 (2009) 605–618.","chicago":"Krueger, Bettina, Silke Haerteis, Limin Yang, Andrea Hartner, Robert Rauh, Christoph Korbmacher, and Alexei Diakov. “Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1.” <i>Cellular Physiology and Biochemistry</i> 24, no. 5–6 (2009): 605–618. <a href=\"https://doi.org/10.1159/000257516\">https://doi.org/10.1159/000257516</a>.","ieee":"B. Krueger <i>et al.</i>, “Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1,” <i>Cellular Physiology and Biochemistry</i>, vol. 24, no. 5–6, pp. 605–618, 2009, doi: <a href=\"https://doi.org/10.1159/000257516\">10.1159/000257516</a>.","apa":"Krueger, B., Haerteis, S., Yang, L., Hartner, A., Rauh, R., Korbmacher, C., &#38; Diakov, A. (2009). Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1. <i>Cellular Physiology and Biochemistry</i>, <i>24</i>(5–6), 605–618. <a href=\"https://doi.org/10.1159/000257516\">https://doi.org/10.1159/000257516</a>","bibtex":"@article{Krueger_Haerteis_Yang_Hartner_Rauh_Korbmacher_Diakov_2009, title={Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1}, volume={24}, DOI={<a href=\"https://doi.org/10.1159/000257516\">10.1159/000257516</a>}, number={5–6}, journal={Cellular Physiology and Biochemistry}, publisher={S. Karger AG}, author={Krueger, Bettina and Haerteis, Silke and Yang, Limin and Hartner, Andrea and Rauh, Robert and Korbmacher, Christoph and Diakov, Alexei}, year={2009}, pages={605–618} }","ama":"Krueger B, Haerteis S, Yang L, et al. Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1. <i>Cellular Physiology and Biochemistry</i>. 2009;24(5-6):605–618. doi:<a href=\"https://doi.org/10.1159/000257516\">10.1159/000257516</a>","mla":"Krueger, Bettina, et al. “Cholesterol Depletion of the Plasma Membrane Prevents Activation of the Epithelial Sodium Channel (ENaC) by SGK1.” <i>Cellular Physiology and Biochemistry</i>, vol. 24, no. 5–6, S. Karger AG, 2009, pp. 605–618, doi:<a href=\"https://doi.org/10.1159/000257516\">10.1159/000257516</a>."},"issue":"5-6","publication":"Cellular Physiology and Biochemistry","abstract":[{"text":"The lipid environment of the epithelial sodium channel (ENaC) and its possible association with so-called lipid rafts may be relevant to its function. The aim of our study was to confirm the association of ENaC with lipid rafts and to analyze the effect of cholesterol depletion of the plasma membrane by methyl-beta-cyclodextrin (MbetaCD) on channel function and regulation. Using sucrose density gradient centrifugation we demonstrated that a significant portion of ENaC protein distributes to low density fractions thought to be typical lipid raft fractions. Importantly, cholesterol depletion of cell lysate by MbetaCD shifted ENaC to non-raft fractions of higher density. Live cell imaging demonstrated that treatment with MbetaCD largely reduced filipin staining over time, confirming cholesterol depletion of the plasma membrane. For electrophysiological studies intact oocytes were exposed to 20 mM MbetaCD for three hours. MbetaCD treatment had no consistent effect on baseline whole-cell ENaC currents. In addition to the typical single channel conductance of about 5 pS, subconductance states of ENaC were occasionally observed in patches from MbetaCD treated but not from control oocytes. Importantly, in outside-out patch clamp recordings the stimulatory effect of recombinant SGK1 in the pipette solution was essentially abolished in oocytes pretreated with MbetaCD. These results indicate that ENaC activation by cytosolic SGK1 is compromised by removing cholesterol from the plasma membrane. Thus, ENaC activation by SGK1 may require the presence of an intact lipid environment and/or of lipid rafts as signalling platform.","lang":"eng"}],"date_created":"2024-06-30T13:52:19Z","department":[{"_id":"35"},{"_id":"22"}],"type":"journal_article"}]