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Increase in prevalence of adiposity between the ages of 7 and 11 years reflects lower remission rates during this period. <i>Pediatric Obesity</i>, 13–20. <a href=\"https://doi.org/10.1111/j.2047-6310.2012.00084.x\">https://doi.org/10.1111/j.2047-6310.2012.00084.x</a>"},"date_updated":"2022-01-06T06:57:44Z","date_created":"2021-11-23T16:54:14Z","author":[{"last_name":"von Kries","full_name":"von Kries, R.","first_name":"R."},{"full_name":"Reulen, H.","last_name":"Reulen","first_name":"H."},{"first_name":"O.","full_name":"Bayer, O.","last_name":"Bayer"},{"last_name":"Riedel","full_name":"Riedel, C.","first_name":"C."},{"first_name":"K.","last_name":"Diethelm","full_name":"Diethelm, K."},{"last_name":"Buyken","full_name":"Buyken, Anette","id":"65985","first_name":"Anette"}],"title":"Increase in prevalence of adiposity between the ages of 7 and 11 years reflects lower remission rates during this period","doi":"10.1111/j.2047-6310.2012.00084.x","publication":"Pediatric Obesity","type":"journal_article","status":"public","_id":"27767","department":[{"_id":"17"},{"_id":"22"},{"_id":"571"}],"user_id":"61597","language":[{"iso":"eng"}]},{"type":"journal_article","publication":"DMW - Deutsche Medizinische Wochenschrift","status":"public","_id":"27786","user_id":"61597","department":[{"_id":"17"},{"_id":"22"},{"_id":"571"}],"language":[{"iso":"ger"}],"publication_status":"published","publication_identifier":{"issn":["0012-0472","1439-4413"]},"year":"2012","citation":{"apa":"Hauner, H., Bechthold, A., Boeing, H., Brönstrup, A., Buyken, A., Leschik-Bonnet, E., Linseisen, J., Schulze, M., Strohm, D., &#38; Wolfram, G. (2012). Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten. <i>DMW - Deutsche Medizinische Wochenschrift</i>, 389–393. <a href=\"https://doi.org/10.1055/s-0031-1298916\">https://doi.org/10.1055/s-0031-1298916</a>","short":"H. Hauner, A. Bechthold, H. Boeing, A. Brönstrup, A. Buyken, E. Leschik-Bonnet, J. Linseisen, M. Schulze, D. Strohm, G. Wolfram, DMW - Deutsche Medizinische Wochenschrift (2012) 389–393.","bibtex":"@article{Hauner_Bechthold_Boeing_Brönstrup_Buyken_Leschik-Bonnet_Linseisen_Schulze_Strohm_Wolfram_2012, title={Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten}, DOI={<a href=\"https://doi.org/10.1055/s-0031-1298916\">10.1055/s-0031-1298916</a>}, journal={DMW - Deutsche Medizinische Wochenschrift}, author={Hauner, H. and Bechthold, A. and Boeing, H. and Brönstrup, A. and Buyken, Anette and Leschik-Bonnet, E. and Linseisen, J. and Schulze, M. and Strohm, D. and Wolfram, G.}, year={2012}, pages={389–393} }","mla":"Hauner, H., et al. “Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten.” <i>DMW - Deutsche Medizinische Wochenschrift</i>, 2012, pp. 389–93, doi:<a href=\"https://doi.org/10.1055/s-0031-1298916\">10.1055/s-0031-1298916</a>.","ama":"Hauner H, Bechthold A, Boeing H, et al. Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten. <i>DMW - Deutsche Medizinische Wochenschrift</i>. Published online 2012:389-393. doi:<a href=\"https://doi.org/10.1055/s-0031-1298916\">10.1055/s-0031-1298916</a>","chicago":"Hauner, H., A. Bechthold, H. Boeing, A. Brönstrup, Anette Buyken, E. Leschik-Bonnet, J. Linseisen, M. Schulze, D. Strohm, and G. Wolfram. “Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten.” <i>DMW - Deutsche Medizinische Wochenschrift</i>, 2012, 389–93. <a href=\"https://doi.org/10.1055/s-0031-1298916\">https://doi.org/10.1055/s-0031-1298916</a>.","ieee":"H. Hauner <i>et al.</i>, “Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten,” <i>DMW - Deutsche Medizinische Wochenschrift</i>, pp. 389–393, 2012, doi: <a href=\"https://doi.org/10.1055/s-0031-1298916\">10.1055/s-0031-1298916</a>."},"page":"389-393","date_updated":"2022-01-06T06:57:45Z","date_created":"2021-11-25T11:52:55Z","author":[{"first_name":"H.","last_name":"Hauner","full_name":"Hauner, H."},{"last_name":"Bechthold","full_name":"Bechthold, A.","first_name":"A."},{"first_name":"H.","last_name":"Boeing","full_name":"Boeing, H."},{"first_name":"A.","full_name":"Brönstrup, A.","last_name":"Brönstrup"},{"first_name":"Anette","last_name":"Buyken","id":"65985","full_name":"Buyken, Anette"},{"first_name":"E.","full_name":"Leschik-Bonnet, E.","last_name":"Leschik-Bonnet"},{"first_name":"J.","full_name":"Linseisen, J.","last_name":"Linseisen"},{"full_name":"Schulze, M.","last_name":"Schulze","first_name":"M."},{"first_name":"D.","last_name":"Strohm","full_name":"Strohm, D."},{"first_name":"G.","last_name":"Wolfram","full_name":"Wolfram, G."}],"title":"Kohlenhydratzufuhr und Prävention ausgewählter ernährungsmitbedingter Krankheiten","doi":"10.1055/s-0031-1298916"},{"publication":"Nutrition Reviews","type":"journal_article","status":"public","_id":"27787","department":[{"_id":"17"},{"_id":"22"},{"_id":"571"}],"user_id":"61597","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0029-6643"]},"publication_status":"published","year":"2012","page":"133-152","citation":{"apa":"Cheng, G., Buyken, A., Shi, L., Karaolis-Danckert, N., Kroke, A., Wudy, S. A., Degen, G. H., &#38; Remer, T. (2012). Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty. <i>Nutrition Reviews</i>, 133–152. <a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">https://doi.org/10.1111/j.1753-4887.2011.00461.x</a>","bibtex":"@article{Cheng_Buyken_Shi_Karaolis-Danckert_Kroke_Wudy_Degen_Remer_2012, title={Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty}, DOI={<a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">10.1111/j.1753-4887.2011.00461.x</a>}, journal={Nutrition Reviews}, author={Cheng, Guo and Buyken, Anette and Shi, Lijie and Karaolis-Danckert, Nadina and Kroke, Anja and Wudy, Stefan A and Degen, Gisela H and Remer, Thomas}, year={2012}, pages={133–152} }","short":"G. Cheng, A. Buyken, L. Shi, N. Karaolis-Danckert, A. Kroke, S.A. Wudy, G.H. Degen, T. Remer, Nutrition Reviews (2012) 133–152.","mla":"Cheng, Guo, et al. “Beyond Overweight: Nutrition as an Important Lifestyle Factor Influencing Timing of Puberty.” <i>Nutrition Reviews</i>, 2012, pp. 133–52, doi:<a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">10.1111/j.1753-4887.2011.00461.x</a>.","chicago":"Cheng, Guo, Anette Buyken, Lijie Shi, Nadina Karaolis-Danckert, Anja Kroke, Stefan A Wudy, Gisela H Degen, and Thomas Remer. “Beyond Overweight: Nutrition as an Important Lifestyle Factor Influencing Timing of Puberty.” <i>Nutrition Reviews</i>, 2012, 133–52. <a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">https://doi.org/10.1111/j.1753-4887.2011.00461.x</a>.","ieee":"G. Cheng <i>et al.</i>, “Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty,” <i>Nutrition Reviews</i>, pp. 133–152, 2012, doi: <a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">10.1111/j.1753-4887.2011.00461.x</a>.","ama":"Cheng G, Buyken A, Shi L, et al. Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty. <i>Nutrition Reviews</i>. Published online 2012:133-152. doi:<a href=\"https://doi.org/10.1111/j.1753-4887.2011.00461.x\">10.1111/j.1753-4887.2011.00461.x</a>"},"date_updated":"2022-01-06T06:57:45Z","author":[{"last_name":"Cheng","full_name":"Cheng, Guo","first_name":"Guo"},{"first_name":"Anette","last_name":"Buyken","id":"65985","full_name":"Buyken, Anette"},{"last_name":"Shi","full_name":"Shi, Lijie","first_name":"Lijie"},{"first_name":"Nadina","full_name":"Karaolis-Danckert, Nadina","last_name":"Karaolis-Danckert"},{"first_name":"Anja","last_name":"Kroke","full_name":"Kroke, Anja"},{"last_name":"Wudy","full_name":"Wudy, Stefan A","first_name":"Stefan A"},{"last_name":"Degen","full_name":"Degen, Gisela H","first_name":"Gisela H"},{"first_name":"Thomas","last_name":"Remer","full_name":"Remer, Thomas"}],"date_created":"2021-11-25T11:54:50Z","title":"Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty","doi":"10.1111/j.1753-4887.2011.00461.x"},{"year":"2012","quality_controlled":"1","title":"A Proof-of-Concept of D³ Record Mining using Domain-Dependent Data","publisher":"SERSC","date_created":"2018-01-30T12:55:27Z","abstract":[{"lang":"eng","text":"Our purpose is to perform data record extraction from onlineevent calendars exploiting sublanguage and domain characteristics. We therefore use so-called domain-dependent data (D³) completely based on language-specific key expressions and HTML patterns to recognize every single event given on the investigated web page. One of the most remarkable advantages of our method is that it does not require any additional classification steps based on machine learning algorithms or keyword extraction methods; it is a so-called one-step mining technique. Moreover, another important criteria is that our system is robust to DOM and layout modifications made by web designers. Thus, preliminary experimental results are provided to demonstrate proof-of-concept of such an approach tested on websites in the German opera domain. Furthermore, we could show that our proposed technique outperforms other data record mining applications run on event sites."}],"publication":"Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012","language":[{"iso":"eng"}],"place":"Sandy Bay, Australia","citation":{"mla":"Lee, Yeong Su, et al. “A Proof-of-Concept of D<sup>3</sup> Record Mining Using Domain-Dependent Data.” <i>Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012</i>, edited by Chin-Chen Chang et al., vol. 5, SERSC, 2012, pp. 134–39.","short":"Y.S. Lee, M. Geierhos, S.-K. Song, H. Jung, in: C.-C. Chang, Y.E. Gelogo, R.E. Caytiles (Eds.), Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012, SERSC, Sandy Bay, Australia, 2012, pp. 134–139.","bibtex":"@inproceedings{Lee_Geierhos_Song_Jung_2012, place={Sandy Bay, Australia}, series={Advanced Science and Technology Letters (ASTL)}, title={A Proof-of-Concept of D<sup>3</sup> Record Mining using Domain-Dependent Data}, volume={5}, booktitle={Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012}, publisher={SERSC}, author={Lee, Yeong Su and Geierhos, Michaela and Song, Sa-Kwang and Jung, Hanmin}, editor={Chang, Chin-Chen and Gelogo, Yvette E. and Caytiles, Ronnie E.Editors}, year={2012}, pages={134–139}, collection={Advanced Science and Technology Letters (ASTL)} }","apa":"Lee, Y. S., Geierhos, M., Song, S.-K., &#38; Jung, H. (2012). A Proof-of-Concept of D<sup>3</sup> Record Mining using Domain-Dependent Data. In C.-C. Chang, Y. E. Gelogo, &#38; R. E. Caytiles (Eds.), <i>Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012</i> (Vol. 5, pp. 134–139). Sandy Bay, Australia: SERSC.","ieee":"Y. S. Lee, M. Geierhos, S.-K. Song, and H. Jung, “A Proof-of-Concept of D<sup>3</sup> Record Mining using Domain-Dependent Data,” in <i>Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012</i>, Cebu, Philippines, 2012, vol. 5, pp. 134–139.","chicago":"Lee, Yeong Su, Michaela Geierhos, Sa-Kwang Song, and Hanmin Jung. “A Proof-of-Concept of D<sup>3</sup> Record Mining Using Domain-Dependent Data.” In <i>Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012</i>, edited by Chin-Chen Chang, Yvette E. Gelogo, and Ronnie E. Caytiles, 5:134–39. Advanced Science and Technology Letters (ASTL). Sandy Bay, Australia: SERSC, 2012.","ama":"Lee YS, Geierhos M, Song S-K, Jung H. A Proof-of-Concept of D<sup>3</sup> Record Mining using Domain-Dependent Data. In: Chang C-C, Gelogo YE, Caytiles RE, eds. <i>Software Technology: Prooceedings, International Conference, SoftTech 2012, Cebu, Philippines, May 2012</i>. Vol 5. Advanced Science and Technology Letters (ASTL). Sandy Bay, Australia: SERSC; 2012:134-139."},"page":"134-139","intvolume":"         5","publication_status":"published","publication_identifier":{"issn":["22871233"]},"main_file_link":[{"open_access":"1","url":"https://www.semanticscholar.org/paper/A-Proof-of-Concept-of-D%C2%B3-Record-Mining-using-Data-Lee-Geierhos/6cc05168d8acc6a3d6b25cb0466c01a90fd2fbfc"}],"conference":{"start_date":"2012-05-29","name":"1st International Conference on Software Technology (SoftTech 2012)","location":"Cebu, Philippines","end_date":"2012-05-31"},"oa":"1","date_updated":"2022-01-06T06:50:58Z","author":[{"last_name":"Lee","full_name":"Lee, Yeong Su","first_name":"Yeong Su"},{"first_name":"Michaela","full_name":"Geierhos, Michaela","id":"42496","last_name":"Geierhos","orcid":"0000-0002-8180-5606"},{"first_name":"Sa-Kwang","last_name":"Song","full_name":"Song, Sa-Kwang"},{"full_name":"Jung, Hanmin","last_name":"Jung","first_name":"Hanmin"}],"volume":5,"editor":[{"first_name":"Chin-Chen","full_name":"Chang, Chin-Chen","last_name":"Chang"},{"last_name":"Gelogo","full_name":"Gelogo, Yvette E.","first_name":"Yvette E."},{"first_name":"Ronnie E.","full_name":"Caytiles, Ronnie E.","last_name":"Caytiles"}],"status":"public","type":"conference","extern":"1","_id":"1128","user_id":"13929","series_title":"Advanced Science and Technology Letters (ASTL)","department":[{"_id":"36"},{"_id":"1"},{"_id":"579"}]},{"department":[{"_id":"65"}],"user_id":"14955","_id":"21757","language":[{"iso":"eng"}],"publication":"IEEE Computer Graphics and Applications","type":"journal_article","status":"public","volume":32,"date_created":"2021-04-25T16:15:47Z","author":[{"full_name":"Koning, W. F.","last_name":"Koning","first_name":"W. F."}],"publisher":"IEEE","date_updated":"2022-01-06T06:55:13Z","doi":"10.1109/MCG.2012.106","title":"Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director","issue":"5","page":"81-83","intvolume":"        32","citation":{"ama":"Koning WF. Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director. <i>IEEE Computer Graphics and Applications</i>. 2012;32(5):81-83. doi:<a href=\"https://doi.org/10.1109/MCG.2012.106\">10.1109/MCG.2012.106</a>","chicago":"Koning, W. F. “Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director.” <i>IEEE Computer Graphics and Applications</i> 32, no. 5 (2012): 81–83. <a href=\"https://doi.org/10.1109/MCG.2012.106\">https://doi.org/10.1109/MCG.2012.106</a>.","ieee":"W. F. Koning, “Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director,” <i>IEEE Computer Graphics and Applications</i>, vol. 32, no. 5, pp. 81–83, 2012.","bibtex":"@article{Koning_2012, title={Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director}, volume={32}, DOI={<a href=\"https://doi.org/10.1109/MCG.2012.106\">10.1109/MCG.2012.106</a>}, number={5}, journal={IEEE Computer Graphics and Applications}, publisher={IEEE}, author={Koning, W. F.}, year={2012}, pages={81–83} }","short":"W.F. Koning, IEEE Computer Graphics and Applications 32 (2012) 81–83.","mla":"Koning, W. F. “Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director.” <i>IEEE Computer Graphics and Applications</i>, vol. 32, no. 5, IEEE, 2012, pp. 81–83, doi:<a href=\"https://doi.org/10.1109/MCG.2012.106\">10.1109/MCG.2012.106</a>.","apa":"Koning, W. F. (2012). Teaching 3D Computer Animation to Illustrators: The Instructor as Translator and Technical Director. <i>IEEE Computer Graphics and Applications</i>, <i>32</i>(5), 81–83. <a href=\"https://doi.org/10.1109/MCG.2012.106\">https://doi.org/10.1109/MCG.2012.106</a>"},"year":"2012"},{"_id":"788","department":[{"_id":"75"}],"user_id":"15572","status":"public","publication":"37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012","type":"conference","title":"OpenNetInf - prototyping an information-centric Network Architecture","doi":"10.1109/LCNW.2012.6424044","date_updated":"2022-01-06T07:03:47Z","date_created":"2017-11-27T10:22:26Z","author":[{"last_name":"Dannewitz","full_name":"Dannewitz, Christian","first_name":"Christian"},{"last_name":"Herlich","full_name":"Herlich, Matthias","first_name":"Matthias"},{"first_name":"Holger","full_name":"Karl, Holger","id":"126","last_name":"Karl"}],"year":"2012","page":"1061--1069","citation":{"ieee":"C. Dannewitz, M. Herlich, and H. Karl, “OpenNetInf - prototyping an information-centric Network Architecture,” in <i>37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012</i>, 2012, pp. 1061--1069.","chicago":"Dannewitz, Christian, Matthias Herlich, and Holger Karl. “OpenNetInf - Prototyping an Information-Centric Network Architecture.” In <i>37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012</i>, 1061--1069, 2012. <a href=\"https://doi.org/10.1109/LCNW.2012.6424044\">https://doi.org/10.1109/LCNW.2012.6424044</a>.","ama":"Dannewitz C, Herlich M, Karl H. OpenNetInf - prototyping an information-centric Network Architecture. In: <i>37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012</i>. ; 2012:1061--1069. doi:<a href=\"https://doi.org/10.1109/LCNW.2012.6424044\">10.1109/LCNW.2012.6424044</a>","short":"C. Dannewitz, M. Herlich, H. Karl, in: 37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012, 2012, pp. 1061--1069.","mla":"Dannewitz, Christian, et al. “OpenNetInf - Prototyping an Information-Centric Network Architecture.” <i>37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012</i>, 2012, pp. 1061--1069, doi:<a href=\"https://doi.org/10.1109/LCNW.2012.6424044\">10.1109/LCNW.2012.6424044</a>.","bibtex":"@inproceedings{Dannewitz_Herlich_Karl_2012, title={OpenNetInf - prototyping an information-centric Network Architecture}, DOI={<a href=\"https://doi.org/10.1109/LCNW.2012.6424044\">10.1109/LCNW.2012.6424044</a>}, booktitle={37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012}, author={Dannewitz, Christian and Herlich, Matthias and Karl, Holger}, year={2012}, pages={1061--1069} }","apa":"Dannewitz, C., Herlich, M., &#38; Karl, H. (2012). OpenNetInf - prototyping an information-centric Network Architecture. In <i>37th Annual IEEE Conference on Local Computer Networks, Workshop Proceedings, Clearwater Beach, FL, USA, October 22-25, 2012</i> (pp. 1061--1069). <a href=\"https://doi.org/10.1109/LCNW.2012.6424044\">https://doi.org/10.1109/LCNW.2012.6424044</a>"}},{"has_accepted_license":"1","page":"9-14","citation":{"bibtex":"@inproceedings{Brandes_Meyer auf der Heide_2012, series={ICPS}, title={Distributed Computing in Fault-Prone Dynamic Networks}, DOI={<a href=\"https://doi.org/10.1145/2414815.2414818\">10.1145/2414815.2414818</a>}, booktitle={Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)}, author={Brandes, Philipp and Meyer auf der Heide, Friedhelm}, year={2012}, pages={9–14}, collection={ICPS} }","mla":"Brandes, Philipp, and Friedhelm Meyer auf der Heide. “Distributed Computing in Fault-Prone Dynamic Networks.” <i>Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)</i>, 2012, pp. 9–14, doi:<a href=\"https://doi.org/10.1145/2414815.2414818\">10.1145/2414815.2414818</a>.","short":"P. Brandes, F. Meyer auf der Heide, in: Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS), 2012, pp. 9–14.","apa":"Brandes, P., &#38; Meyer auf der Heide, F. (2012). Distributed Computing in Fault-Prone Dynamic Networks. In <i>Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)</i> (pp. 9–14). <a href=\"https://doi.org/10.1145/2414815.2414818\">https://doi.org/10.1145/2414815.2414818</a>","ama":"Brandes P, Meyer auf der Heide F. Distributed Computing in Fault-Prone Dynamic Networks. In: <i>Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)</i>. ICPS. ; 2012:9-14. doi:<a href=\"https://doi.org/10.1145/2414815.2414818\">10.1145/2414815.2414818</a>","chicago":"Brandes, Philipp, and Friedhelm Meyer auf der Heide. “Distributed Computing in Fault-Prone Dynamic Networks.” In <i>Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)</i>, 9–14. ICPS, 2012. <a href=\"https://doi.org/10.1145/2414815.2414818\">https://doi.org/10.1145/2414815.2414818</a>.","ieee":"P. Brandes and F. Meyer auf der Heide, “Distributed Computing in Fault-Prone Dynamic Networks,” in <i>Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)</i>, 2012, pp. 9–14."},"year":"2012","author":[{"full_name":"Brandes, Philipp","last_name":"Brandes","first_name":"Philipp"},{"last_name":"Meyer auf der Heide","full_name":"Meyer auf der Heide, Friedhelm","id":"15523","first_name":"Friedhelm"}],"date_created":"2017-10-17T12:42:52Z","date_updated":"2022-01-06T07:02:56Z","doi":"10.1145/2414815.2414818","title":"Distributed Computing in Fault-Prone Dynamic Networks","publication":"Proceedings of the 4th Workshop on Theoretical Aspects of Dynamic Distributed Systems (TADDS)","type":"conference","status":"public","file":[{"file_name":"619-Brandes_MadHTADDS12_01.pdf","access_level":"closed","file_id":"1244","file_size":346044,"creator":"florida","date_created":"2018-03-15T06:47:15Z","date_updated":"2018-03-15T06:47:15Z","relation":"main_file","success":1,"content_type":"application/pdf"}],"abstract":[{"text":"Dynamics in networks is caused by a variety of reasons, like nodes moving in 2D (or 3D) in multihop cellphone networks, joins and leaves in peer-to-peer networks, evolution in social networks, and many others. In order to understand such kinds of dynamics, and to design distributed algorithms that behave well under dynamics, many ways to model dynamics are introduced and analyzed w.r.t. correctness and eciency of distributed algorithms. In [16], Kuhn, Lynch, and Oshman have introduced a very general, worst case type model of dynamics: The edge set of the network may change arbitrarily from step to step, the only restriction is that it is connected at all times and the set of nodes does not change. An extended model demands that a xed connected subnetwork is maintained over each time interval of length T (T-interval dynamics). They have presented, among others, algorithms for counting the number of nodes under such general models of dynamics.In this paper, we generalize their models and algorithms by adding random edge faults, i.e., we consider fault-prone dynamic networks: We assume that an edge currently existing may fail to transmit data with some probability p. We rst observe that strong counting, i.e., each node knows the correct count and stops, is not possible in a model with random edge faults. Our main two positive results are feasibility and runtime bounds for weak counting, i.e., stopping is no longer required (but still a correct count in each node), and for strong counting with an upper bound, i.e., an upper bound N on n is known to all nodes.","lang":"eng"}],"department":[{"_id":"63"}],"series_title":"ICPS","user_id":"15504","_id":"619","project":[{"_id":"1","name":"SFB 901"},{"name":"SFB 901 - Subprojekt A1","_id":"5"},{"name":"SFB 901 - Project Area A","_id":"2"}],"file_date_updated":"2018-03-15T06:47:15Z","ddc":["040"]},{"_id":"16408","department":[{"_id":"63"}],"user_id":"15415","series_title":"Lecture Notes in Computer Science","language":[{"iso":"eng"}],"publication":"Advances in Visual Computing","type":"conference","abstract":[{"lang":"eng","text":"We present a parallel rendering system for heterogeneous PC clusters to visualize massive models. One single, powerful visualization node is supported by a group of backend nodes with weak graphics performance. While the visualization node renders the visible objects, the backend nodes asynchronously perform visibility tests and supply the front end with visible scene objects. The visualization node stores only currently visible objects in its memory, while the scene is distributed among the backend nodes’ memory without redundancy. To efficiently compute the occlusion tests in spite of that each backend node stores only a fraction of the original geometry, we complete the scene by adding highly simplified versions of the objects stored on other nodes. We test our system with 15 backend nodes. It is able to render a ≈ 350,M polygons (≈ 8.5,GiB) large aircraft model with 20, to 30,fps and thus allows a walk-through in real-time.\r\n"}],"status":"public","date_updated":"2022-01-06T06:52:50Z","volume":7431,"date_created":"2020-04-06T07:40:57Z","author":[{"first_name":"Tim","full_name":"Suess, Tim","last_name":"Suess"},{"last_name":"Koch","full_name":"Koch, Clemens","first_name":"Clemens"},{"full_name":"Jähn, Claudius","last_name":"Jähn","first_name":"Claudius"},{"id":"146","full_name":"Fischer, Matthias","last_name":"Fischer","first_name":"Matthias"},{"last_name":"Meyer auf der Heide","id":"15523","full_name":"Meyer auf der Heide, Friedhelm","first_name":"Friedhelm"}],"title":"Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes","doi":"10.1007/978-3-642-33179-4_48","publication_identifier":{"isbn":["9783642331787","9783642331794"],"issn":["0302-9743","1611-3349"]},"publication_status":"published","place":"Berlin, Heidelberg","year":"2012","page":"502-512","intvolume":"      7431","citation":{"ama":"Suess T, Koch C, Jähn C, Fischer M, Meyer auf der Heide F. Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes. In: <i>Advances in Visual Computing</i>. Vol 7431. Lecture Notes in Computer Science. ; 2012:502-512. doi:<a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">10.1007/978-3-642-33179-4_48</a>","ieee":"T. Suess, C. Koch, C. Jähn, M. Fischer, and F. Meyer auf der Heide, “Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes,” in <i>Advances in Visual Computing</i>, 2012, vol. 7431, pp. 502–512, doi: <a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">10.1007/978-3-642-33179-4_48</a>.","chicago":"Suess, Tim, Clemens Koch, Claudius Jähn, Matthias Fischer, and Friedhelm Meyer auf der Heide. “Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes.” In <i>Advances in Visual Computing</i>, 7431:502–12. Lecture Notes in Computer Science. Berlin, Heidelberg, 2012. <a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">https://doi.org/10.1007/978-3-642-33179-4_48</a>.","apa":"Suess, T., Koch, C., Jähn, C., Fischer, M., &#38; Meyer auf der Heide, F. (2012). Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes. <i>Advances in Visual Computing</i>, <i>7431</i>, 502–512. <a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">https://doi.org/10.1007/978-3-642-33179-4_48</a>","short":"T. Suess, C. Koch, C. Jähn, M. Fischer, F. Meyer auf der Heide, in: Advances in Visual Computing, Berlin, Heidelberg, 2012, pp. 502–512.","mla":"Suess, Tim, et al. “Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes.” <i>Advances in Visual Computing</i>, vol. 7431, 2012, pp. 502–12, doi:<a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">10.1007/978-3-642-33179-4_48</a>.","bibtex":"@inproceedings{Suess_Koch_Jähn_Fischer_Meyer auf der Heide_2012, place={Berlin, Heidelberg}, series={Lecture Notes in Computer Science}, title={Asynchronous Occlusion Culling on Heterogeneous PC Clusters for Distributed 3D Scenes}, volume={7431}, DOI={<a href=\"https://doi.org/10.1007/978-3-642-33179-4_48\">10.1007/978-3-642-33179-4_48</a>}, booktitle={Advances in Visual Computing}, author={Suess, Tim and Koch, Clemens and Jähn, Claudius and Fischer, Matthias and Meyer auf der Heide, Friedhelm}, year={2012}, pages={502–512}, collection={Lecture Notes in Computer Science} }"}},{"_id":"22164","department":[{"_id":"219"},{"_id":"624"},{"_id":"367"},{"_id":"321"},{"_id":"9"}],"user_id":"70729","language":[{"iso":"eng"}],"publication":"1st International Conference on Thermo-Mechanically Graded Materials","type":"conference","abstract":[{"text":"Generative production techniques have the advantage of manufacturing parts via an additive process without needing a forming tool. One of these additive manufacturing technologies is \"Fused Deposition Modeling\" (FDM). It is one of the most used additive manufacturing processes to produce prototypes and end-use parts. From a 3D-CAD data set, components and assemblies are manufactured out of thermoplastic material layer by layer by means of an additive process. An extrusion head deposits the molten thermoplastic filament to create each layer with a particular tool path. Due to the thermal fusion the material bonds with the layer beneath and solidifies. Thus a permanent bonding of two layers is formed. In this paper the mechanical data of parts, manufactured with the system Fortus 400mc from Stratasys with the material Ultem*9085 are presented. Tensile and flexural tests according to both, the ASTM and the ISO standard, are conducted. Test specimens are generated with the standard parameters of the native software in different build directions. The tests show different strength and strain characteristics that depend on the given structure as a result of the build direction. Furthermore tensile specimens according to the ASTM standard are generated with changed parameters of the native software to increase the mechanical strength properties. The results are compared to injection molded strength properties.","lang":"eng"}],"status":"public","date_updated":"2022-04-25T07:58:51Z","volume":1,"date_created":"2021-05-14T07:24:35Z","author":[{"first_name":"A.","full_name":"Bagsik, A.","last_name":"Bagsik"},{"full_name":"Schöppner, Volker","id":"20530","last_name":"Schöppner","first_name":"Volker"},{"first_name":"E.","full_name":"Klemp, E.","last_name":"Klemp"}],"title":"Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085","publication_identifier":{"isbn":["9783942267588"]},"quality_controlled":"1","year":"2012","page":"129-134","intvolume":"         1","citation":{"chicago":"Bagsik, A., Volker Schöppner, and E. Klemp. “Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085.” In <i>1st International Conference on Thermo-Mechanically Graded Materials</i>, 1:129–34, 2012.","ieee":"A. Bagsik, V. Schöppner, and E. Klemp, “Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085,” in <i>1st International Conference on Thermo-Mechanically Graded Materials</i>, 2012, vol. 1, pp. 129–134.","ama":"Bagsik A, Schöppner V, Klemp E. Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085. In: <i>1st International Conference on Thermo-Mechanically Graded Materials</i>. Vol 1. ; 2012:129-134.","apa":"Bagsik, A., Schöppner, V., &#38; Klemp, E. (2012). Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085. <i>1st International Conference on Thermo-Mechanically Graded Materials</i>, <i>1</i>, 129–134.","bibtex":"@inproceedings{Bagsik_Schöppner_Klemp_2012, title={Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085}, volume={1}, booktitle={1st International Conference on Thermo-Mechanically Graded Materials}, author={Bagsik, A. and Schöppner, Volker and Klemp, E.}, year={2012}, pages={129–134} }","short":"A. Bagsik, V. Schöppner, E. Klemp, in: 1st International Conference on Thermo-Mechanically Graded Materials, 2012, pp. 129–134.","mla":"Bagsik, A., et al. “Tensile and Flexural Properties of Fused Deposition Modeling Parts Manufactured with ULTEM*9085.” <i>1st International Conference on Thermo-Mechanically Graded Materials</i>, vol. 1, 2012, pp. 129–34."}},{"doi":"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616","title":"Extensive Analysis of the mechanical strength properties of Fused Deposition Modeling Parts manufactured with ULTEM 9085","author":[{"full_name":"Bagsik, A.","last_name":"Bagsik","first_name":"A."},{"last_name":"Schöppner","full_name":"Schöppner, Volker","id":"20530","first_name":"Volker"},{"first_name":"E.","last_name":"Klemp","full_name":"Klemp, E."}],"date_created":"2021-05-07T13:23:04Z","volume":5,"date_updated":"2022-04-25T08:05:52Z","publisher":"Centre for Polymer and Material Technology, Univ. College, Ghent Univ.","citation":{"ama":"Bagsik A, Schöppner V, Klemp E. Extensive Analysis of the mechanical strength properties of Fused Deposition Modeling Parts manufactured with ULTEM 9085. In: <i>5th International Conference on Polymer and Mould Innovations</i>. Vol 5. Centre for Polymer and Material Technology, Univ. College, Ghent Univ.; 2012:266-272. doi:<a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>","ieee":"A. Bagsik, V. Schöppner, and E. Klemp, “Extensive Analysis of the mechanical strength properties of Fused Deposition Modeling Parts manufactured with ULTEM 9085,” in <i>5th International Conference on Polymer and Mould Innovations</i>, 2012, vol. 5, pp. 266–272, doi: <a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>.","chicago":"Bagsik, A., Volker Schöppner, and E. Klemp. “Extensive Analysis of the Mechanical Strength Properties of Fused Deposition Modeling Parts Manufactured with ULTEM 9085.” In <i>5th International Conference on Polymer and Mould Innovations</i>, 5:266–72. Ghent: Centre for Polymer and Material Technology, Univ. College, Ghent Univ., 2012. <a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>.","bibtex":"@inproceedings{Bagsik_Schöppner_Klemp_2012, place={Ghent}, title={Extensive Analysis of the mechanical strength properties of Fused Deposition Modeling Parts manufactured with ULTEM 9085}, volume={5}, DOI={<a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>}, booktitle={5th International Conference on Polymer and Mould Innovations}, publisher={Centre for Polymer and Material Technology, Univ. College, Ghent Univ.}, author={Bagsik, A. and Schöppner, Volker and Klemp, E.}, year={2012}, pages={266–272} }","mla":"Bagsik, A., et al. “Extensive Analysis of the Mechanical Strength Properties of Fused Deposition Modeling Parts Manufactured with ULTEM 9085.” <i>5th International Conference on Polymer and Mould Innovations</i>, vol. 5, Centre for Polymer and Material Technology, Univ. College, Ghent Univ., 2012, pp. 266–72, doi:<a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>.","short":"A. Bagsik, V. Schöppner, E. Klemp, in: 5th International Conference on Polymer and Mould Innovations, Centre for Polymer and Material Technology, Univ. College, Ghent Univ., Ghent, 2012, pp. 266–272.","apa":"Bagsik, A., Schöppner, V., &#38; Klemp, E. (2012). Extensive Analysis of the mechanical strength properties of Fused Deposition Modeling Parts manufactured with ULTEM 9085. <i>5th International Conference on Polymer and Mould Innovations</i>, <i>5</i>, 266–272. <a href=\"https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616\">https://www.tib.eu/de/suchen/id/TIBKAT%3A756276616</a>"},"page":"266-272","intvolume":"         5","year":"2012","place":"Ghent","quality_controlled":"1","language":[{"iso":"eng"}],"user_id":"70729","department":[{"_id":"219"},{"_id":"624"},{"_id":"367"},{"_id":"321"},{"_id":"9"}],"_id":"22024","status":"public","abstract":[{"lang":"eng","text":"Generative production techniques have the advantage of manufacturing parts via an additive process without needing a forming tool. One of these additive manufacturing technologies is “Fused Deposition Modeling” (FDM). It is one of the most used additive manufacturing processes to produce prototypes and end-use parts. From a 3D-CAD data set, components and assemblies are manufactured out of thermoplastic material layer by layer by means of an additive process. An extrusion head deposits the molten thermoplastic filament to create each layer with a particular tool path. In this paper the mechanical data of parts, manufactured with the system Fortus 400mc from Stratasys with the material Ultem*9085 are presented. Tensile specimens are generated with the standard parameters as well as with changed parameters of the native software to analyze the influence of these parameters on the mechanical strength properties. The tensile tests show different strength and strain characteristics that depend on the given structure and as a result of the build direction. Furthermore the toolpath parameters have an effect on the strength characteristics and the break behavior. In addition, tensile specimens are tested under the influence of different temperatures and after a thermal cycling. "}],"type":"conference","publication":"5th International Conference on Polymer and Mould Innovations"},{"department":[{"_id":"607"}],"user_id":"90934","_id":"49699","language":[{"iso":"ger"}],"publication":"GLEIS 22 - Fünfundzwanzig Jahre Konzerte.","type":"book_chapter","status":"public","editor":[{"first_name":"David","last_name":"Skroblin","full_name":"Skroblin, David"},{"full_name":"Dietrich, Frank","last_name":"Dietrich","first_name":"Frank"}],"date_created":"2023-12-15T12:23:02Z","author":[{"id":"20747","full_name":"Jacke, Christoph","last_name":"Jacke","first_name":"Christoph"}],"date_updated":"2023-12-15T12:23:09Z","publisher":"Oktober Verlag","title":"Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität.","page":"6-8","citation":{"apa":"Jacke, C. (2012). Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität. In D. Skroblin &#38; F. Dietrich (Eds.), <i>GLEIS 22 - Fünfundzwanzig Jahre Konzerte.</i> (pp. 6–8). Oktober Verlag.","bibtex":"@inbook{Jacke_2012, place={Münster}, title={Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität.}, booktitle={GLEIS 22 - Fünfundzwanzig Jahre Konzerte.}, publisher={Oktober Verlag}, author={Jacke, Christoph}, editor={Skroblin, David and Dietrich, Frank}, year={2012}, pages={6–8} }","mla":"Jacke, Christoph. “Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität.” <i>GLEIS 22 - Fünfundzwanzig Jahre Konzerte.</i>, edited by David Skroblin and Frank Dietrich, Oktober Verlag, 2012, pp. 6–8.","short":"C. Jacke, in: D. Skroblin, F. Dietrich (Eds.), GLEIS 22 - Fünfundzwanzig Jahre Konzerte., Oktober Verlag, Münster, 2012, pp. 6–8.","ieee":"C. Jacke, “Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität.,” in <i>GLEIS 22 - Fünfundzwanzig Jahre Konzerte.</i>, D. Skroblin and F. Dietrich, Eds. Münster: Oktober Verlag, 2012, pp. 6–8.","chicago":"Jacke, Christoph. “Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität.” In <i>GLEIS 22 - Fünfundzwanzig Jahre Konzerte.</i>, edited by David Skroblin and Frank Dietrich, 6–8. Münster: Oktober Verlag, 2012.","ama":"Jacke C. Der Club „Gleis 22\". 25 Jahre andere Räume, andere Musiken, Kommunikation und Kreativität. In: Skroblin D, Dietrich F, eds. <i>GLEIS 22 - Fünfundzwanzig Jahre Konzerte.</i> Oktober Verlag; 2012:6-8."},"year":"2012","place":"Münster"},{"status":"public","abstract":[{"lang":"eng","text":"Purpose: The epithelial sodium channel (ENaC) is typically expressed in sodium-absorbing epithelia. Several reports suggest that ENaC is also expressed in ocular tissues and may play a role in aqueous humor secretion and glaucoma. However, the precise localization of ENaC in the human eye is still unclear. Here, the authors studied ENaC expression in 12 normal human donor eyes and in six eyes of patients with glaucoma. Methods: Quantitative real-time PCR was used to investigate the expression of $\\alpha$-, $\\beta$-, $\\gamma$-, and $\\delta$-ENaC transcripts in ocular tissues. In addition, the authors performed immunohistochemical studies using recently generated antibodies against human $\\beta$- and $\\gamma$-ENaC. Results: At the mRNA level, all four ENaC subunits were found to be expressed in a wide range of ocular tissues from normal and glaucomatous human eyes, with the cornea, ciliary body, iris, and retina showing the highest expression levels. At the protein level, $\\beta$- and $\\gamma$-ENaC subunits showed distinct distribution patterns and could be immunolocalized primarily to the cell membranes of epithelial cells of the cornea and to the conjunctiva, iris, ciliary body, lens, and retinal pigment epithelium but also to vascular endothelial cells, smooth muscle cells, stromal cells, and retinal neurons. The authors found no altered mRNA level of any subunit in glaucomatous eyes. Conclusions: All four ENaC subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) are expressed in the normal human eye, with distinct localization of subunits possibly reflecting different functional states of the channel. The (patho-)physiological roles of ENaC in the various localizations in the eye remain to be determined."}],"type":"journal_article","publication":"Investigative Opthalmology & Visual Science","language":[{"iso":"eng"}],"user_id":"49428","department":[{"_id":"35"},{"_id":"22"}],"_id":"54937","citation":{"ama":"Krueger B, Schlötzer-Schrehardt U, Haerteis S, et al. Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations. <i>Investigative Opthalmology &#38; Visual Science</i>. 2012;53(2):596–604. doi:<a href=\"https://doi.org/10.1167/iovs.11-8581\">10.1167/iovs.11-8581</a>","chicago":"Krueger, Bettina, Ursula Schlötzer-Schrehardt, Silke Haerteis, Matthias Zenkel, Verena E. Chankiewitz, Kerstin U. Amann, Friedrich E. Kruse, and Christoph Korbmacher. “Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations.” <i>Investigative Opthalmology &#38; Visual Science</i> 53, no. 2 (2012): 596–604. <a href=\"https://doi.org/10.1167/iovs.11-8581\">https://doi.org/10.1167/iovs.11-8581</a>.","ieee":"B. Krueger <i>et al.</i>, “Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations,” <i>Investigative Opthalmology &#38; Visual Science</i>, vol. 53, no. 2, pp. 596–604, 2012, doi: <a href=\"https://doi.org/10.1167/iovs.11-8581\">10.1167/iovs.11-8581</a>.","bibtex":"@article{Krueger_Schlötzer-Schrehardt_Haerteis_Zenkel_Chankiewitz_Amann_Kruse_Korbmacher_2012, title={Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations}, volume={53}, DOI={<a href=\"https://doi.org/10.1167/iovs.11-8581\">10.1167/iovs.11-8581</a>}, number={2}, journal={Investigative Opthalmology &#38; Visual Science}, publisher={Association for Research in Vision and Ophthalmology (ARVO)}, author={Krueger, Bettina and Schlötzer-Schrehardt, Ursula and Haerteis, Silke and Zenkel, Matthias and Chankiewitz, Verena E. and Amann, Kerstin U. and Kruse, Friedrich E. and Korbmacher, Christoph}, year={2012}, pages={596–604} }","short":"B. Krueger, U. Schlötzer-Schrehardt, S. Haerteis, M. Zenkel, V.E. Chankiewitz, K.U. Amann, F.E. Kruse, C. Korbmacher, Investigative Opthalmology &#38; Visual Science 53 (2012) 596–604.","mla":"Krueger, Bettina, et al. “Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations.” <i>Investigative Opthalmology &#38; Visual Science</i>, vol. 53, no. 2, Association for Research in Vision and Ophthalmology (ARVO), 2012, pp. 596–604, doi:<a href=\"https://doi.org/10.1167/iovs.11-8581\">10.1167/iovs.11-8581</a>.","apa":"Krueger, B., Schlötzer-Schrehardt, U., Haerteis, S., Zenkel, M., Chankiewitz, V. E., Amann, K. U., Kruse, F. E., &#38; Korbmacher, C. (2012). Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations. <i>Investigative Opthalmology &#38; Visual Science</i>, <i>53</i>(2), 596–604. <a href=\"https://doi.org/10.1167/iovs.11-8581\">https://doi.org/10.1167/iovs.11-8581</a>"},"page":"596–604","intvolume":"        53","year":"2012","issue":"2","doi":"10.1167/iovs.11-8581","title":"Four Subunits ($\\alpha$$\\beta$$\\gamma$$\\delta$) of the Epithelial Sodium Channel (ENaC) Are Expressed in the Human Eye in Various Locations","date_created":"2024-06-30T13:51:35Z","author":[{"last_name":"Krueger","orcid":"0000-0001-5351-1785","full_name":"Krueger, Bettina","id":"49428","first_name":"Bettina"},{"first_name":"Ursula","last_name":"Schlötzer-Schrehardt","full_name":"Schlötzer-Schrehardt, Ursula"},{"full_name":"Haerteis, Silke","last_name":"Haerteis","first_name":"Silke"},{"first_name":"Matthias","last_name":"Zenkel","full_name":"Zenkel, Matthias"},{"last_name":"Chankiewitz","full_name":"Chankiewitz, Verena E.","first_name":"Verena E."},{"first_name":"Kerstin U.","last_name":"Amann","full_name":"Amann, Kerstin U."},{"last_name":"Kruse","full_name":"Kruse, Friedrich E.","first_name":"Friedrich E."},{"full_name":"Korbmacher, Christoph","last_name":"Korbmacher","first_name":"Christoph"}],"volume":53,"date_updated":"2024-06-30T13:52:14Z","publisher":"Association for Research in Vision and Ophthalmology (ARVO)"},{"issue":"1","intvolume":"        10","citation":{"apa":"Zuehlke, J., Ebenau, A., Krueger, B., &#38; Goppelt-Struebe, M. (2012). Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\\beta$ in human tubular epithelial cells. <i>Cell Communication and Signaling</i>, <i>10</i>(1). <a href=\"https://doi.org/10.1186/1478-811x-10-25\">https://doi.org/10.1186/1478-811x-10-25</a>","bibtex":"@article{Zuehlke_Ebenau_Krueger_Goppelt-Struebe_2012, title={Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\\beta$ in human tubular epithelial cells}, volume={10}, DOI={<a href=\"https://doi.org/10.1186/1478-811x-10-25\">10.1186/1478-811x-10-25</a>}, number={1}, journal={Cell Communication and Signaling}, publisher={Springer}, author={Zuehlke, Jonathan and Ebenau, Astrid and Krueger, Bettina and Goppelt-Struebe, Margarete}, year={2012} }","short":"J. Zuehlke, A. Ebenau, B. Krueger, M. Goppelt-Struebe, Cell Communication and Signaling 10 (2012).","mla":"Zuehlke, Jonathan, et al. “Vectorial Secretion of CTGF as a Cell-Type Specific Response to LPA and TGF-$\\beta$ in Human Tubular Epithelial Cells.” <i>Cell Communication and Signaling</i>, vol. 10, no. 1, Springer, 2012, doi:<a href=\"https://doi.org/10.1186/1478-811x-10-25\">10.1186/1478-811x-10-25</a>.","ama":"Zuehlke J, Ebenau A, Krueger B, Goppelt-Struebe M. Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\\beta$ in human tubular epithelial cells. <i>Cell Communication and Signaling</i>. 2012;10(1). doi:<a href=\"https://doi.org/10.1186/1478-811x-10-25\">10.1186/1478-811x-10-25</a>","ieee":"J. Zuehlke, A. Ebenau, B. Krueger, and M. Goppelt-Struebe, “Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\\beta$ in human tubular epithelial cells,” <i>Cell Communication and Signaling</i>, vol. 10, no. 1, 2012, doi: <a href=\"https://doi.org/10.1186/1478-811x-10-25\">10.1186/1478-811x-10-25</a>.","chicago":"Zuehlke, Jonathan, Astrid Ebenau, Bettina Krueger, and Margarete Goppelt-Struebe. “Vectorial Secretion of CTGF as a Cell-Type Specific Response to LPA and TGF-$\\beta$ in Human Tubular Epithelial Cells.” <i>Cell Communication and Signaling</i> 10, no. 1 (2012). <a href=\"https://doi.org/10.1186/1478-811x-10-25\">https://doi.org/10.1186/1478-811x-10-25</a>."},"year":"2012","volume":10,"author":[{"last_name":"Zuehlke","full_name":"Zuehlke, Jonathan","first_name":"Jonathan"},{"first_name":"Astrid","full_name":"Ebenau, Astrid","last_name":"Ebenau"},{"first_name":"Bettina","full_name":"Krueger, Bettina","id":"49428","orcid":"0000-0001-5351-1785","last_name":"Krueger"},{"first_name":"Margarete","full_name":"Goppelt-Struebe, Margarete","last_name":"Goppelt-Struebe"}],"date_created":"2024-06-30T13:45:36Z","publisher":"Springer","date_updated":"2024-06-30T13:45:48Z","doi":"10.1186/1478-811x-10-25","title":"Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-$\\beta$ in human tubular epithelial cells","publication":"Cell Communication and Signaling","type":"journal_article","status":"public","abstract":[{"lang":"eng","text":"Background: Increased expression of the pro-fibrotic protein connective tissue growth factor (CTGF) has been detected in injured kidneys and elevated urinary levels of CTGF are discussed as prognostic marker of chronic kidney disease. There is evidence that epithelial cells lining the renal tubular system contribute to uptake and secretion of CTGF. However, the role of different types of tubular epithelial cells in these processes so far has not been addressed in primary cultures of human cells. Results: Tubular epithelial cells of proximal and distal origin were isolated from human kidneys and cultured as polarized cells in insert wells. The pro-fibrotic stimuli lysophosphatidic acid (LPA) and transforming growth factor $\\beta$ (TGF-$\\beta$) were used to induce CTGF secretion.LPA activated CTGF secretion in proximal tubular cells when applied from either the apical or the basolateral side as shown by immunocytochemistry. CTGF was secreted exclusively to the apical side. Signaling pathways activated by LPA included MAP kinase and Rho kinase signaling. TGF-$\\beta$ applied from either side also stimulated CTGF secretion primarily to the apical side with little basolateral release.Interestingly, TGF-$\\beta$ activation induced different signaling pathways depending on the side of TGF-$\\beta$ application. Smad signaling was almost exclusively activated from the basolateral side most prominently in cells of distal origin. Only part of these cells also synthesized CTGF indicating that Smad activation alone was not sufficient for CTGF induction. MAP kinases were involved in apical TGF-$\\beta$-mediated activation of CTGF synthesis in proximal cells and a subset of epithelial cells of distal origin. This subpopulation of distal tubular cells was also able to internalize recombinant apical CTGF, in addition to proximal cells which were the main cells to take up exogenous CTGF. Conclusions: Analysis of polarized human primary renal epithelial cells in a transwell system shows that vectorial secretion of the pro-fibrotic protein CTGF depends on the cell type, the stimulus and the signaling pathway activated. In all conditions, CTGF was secreted mainly to the apical side upon TGF-$\\beta$ and LPA treatment and therefore, likely contributes to increased urinary CTGF levels in vivo. Moreover, CTGF secreted basolaterally may be active as paracrine pro-fibrotic mediator."}],"department":[{"_id":"35"},{"_id":"22"}],"user_id":"49428","_id":"54930","language":[{"iso":"eng"}]},{"year":"2012","citation":{"chicago":"Nesterov, Viatcheslav, Anke Dahlmann, Bettina Krueger, Marko Bertog, Johannes Loffing, and Christoph Korbmacher. “Aldosterone-Dependent and -Independent Regulation of the Epithelial Sodium Channel (ENaC) in Mouse Distal Nephron.” <i>American Journal of Physiology-Renal Physiology</i> 303, no. 9 (2012): F1289–F1299. <a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">https://doi.org/10.1152/ajprenal.00247.2012</a>.","ieee":"V. Nesterov, A. Dahlmann, B. Krueger, M. Bertog, J. Loffing, and C. Korbmacher, “Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron,” <i>American Journal of Physiology-Renal Physiology</i>, vol. 303, no. 9, pp. F1289–F1299, 2012, doi: <a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">10.1152/ajprenal.00247.2012</a>.","apa":"Nesterov, V., Dahlmann, A., Krueger, B., Bertog, M., Loffing, J., &#38; Korbmacher, C. (2012). Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. <i>American Journal of Physiology-Renal Physiology</i>, <i>303</i>(9), F1289–F1299. <a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">https://doi.org/10.1152/ajprenal.00247.2012</a>","ama":"Nesterov V, Dahlmann A, Krueger B, Bertog M, Loffing J, Korbmacher C. Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. <i>American Journal of Physiology-Renal Physiology</i>. 2012;303(9):F1289–F1299. doi:<a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">10.1152/ajprenal.00247.2012</a>","bibtex":"@article{Nesterov_Dahlmann_Krueger_Bertog_Loffing_Korbmacher_2012, title={Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron}, volume={303}, DOI={<a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">10.1152/ajprenal.00247.2012</a>}, number={9}, journal={American Journal of Physiology-Renal Physiology}, publisher={American Physiological Society}, author={Nesterov, Viatcheslav and Dahlmann, Anke and Krueger, Bettina and Bertog, Marko and Loffing, Johannes and Korbmacher, Christoph}, year={2012}, pages={F1289–F1299} }","short":"V. Nesterov, A. Dahlmann, B. Krueger, M. Bertog, J. Loffing, C. Korbmacher, American Journal of Physiology-Renal Physiology 303 (2012) F1289–F1299.","mla":"Nesterov, Viatcheslav, et al. “Aldosterone-Dependent and -Independent Regulation of the Epithelial Sodium Channel (ENaC) in Mouse Distal Nephron.” <i>American Journal of Physiology-Renal Physiology</i>, vol. 303, no. 9, American Physiological Society, 2012, pp. F1289–F1299, doi:<a href=\"https://doi.org/10.1152/ajprenal.00247.2012\">10.1152/ajprenal.00247.2012</a>."},"page":"F1289–F1299","intvolume":"       303","issue":"9","title":"Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron","doi":"10.1152/ajprenal.00247.2012","date_updated":"2024-06-30T13:49:30Z","publisher":"American Physiological Society","date_created":"2024-06-30T13:49:18Z","author":[{"full_name":"Nesterov, Viatcheslav","last_name":"Nesterov","first_name":"Viatcheslav"},{"full_name":"Dahlmann, Anke","last_name":"Dahlmann","first_name":"Anke"},{"id":"49428","full_name":"Krueger, Bettina","orcid":"0000-0001-5351-1785","last_name":"Krueger","first_name":"Bettina"},{"last_name":"Bertog","full_name":"Bertog, Marko","first_name":"Marko"},{"first_name":"Johannes","full_name":"Loffing, Johannes","last_name":"Loffing"},{"last_name":"Korbmacher","full_name":"Korbmacher, Christoph","first_name":"Christoph"}],"volume":303,"abstract":[{"text":"Aldosterone is thought to be the main hormone to stimulate the epithelial sodium channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) comprising the late distal convoluted tubule (DCT2), the connecting tubule (CNT) and the entire collecting duct (CD). There is immunohistochemical evidence for an axial gradient of ENaC expression along the ASDN with highest expression in the DCT2 and CNT. However, most of our knowledge about renal ENaC function stems from studies in the cortical collecting duct (CCD). Here we investigated ENaC function in the transition zone of DCT2/CNT or CNT/CCD microdissected from mice maintained on different sodium diets to vary plasma aldosterone levels. Single-channel recordings demonstrated amiloride-sensitive Na(+) channels in DCT2/CNT with biophysical properties typical for ENaC previously described in CNT/CCD. In animals maintained on a standard salt diet, the average ENaC-mediated whole cell current ($\\Delta$I(ami)) was higher in DCT2/CNT than in CNT/CCD. A low salt diet increased $\\Delta$I(ami) in CNT/CCD but had little effect on $\\Delta$I(ami) in DCT2/CNT. To investigate whether aldosterone is necessary for ENaC activity in the DCT2/CNT, we used aldosterone synthase knockout (AS(-/-)) mice that lack aldosterone. In CNT/CCD of AS(-/-) mice, $\\Delta$I(ami) was lower than that in wild-type (WT) animals and was not stimulated by a low salt diet. In contrast, in DCT2/CNT of AS(-/-) mice, $\\Delta$I(ami) was similar to that in DCT2/CNT of WT animals both on a standard and on a low salt diet. We conclude that ENaC function in the DCT2/CNT is largely independent of aldosterone which is in contrast to its known aldosterone sensitivity in CNT/CCD.","lang":"eng"}],"status":"public","type":"journal_article","publication":"American Journal of Physiology-Renal Physiology","language":[{"iso":"eng"}],"_id":"54934","user_id":"49428","department":[{"_id":"35"},{"_id":"22"}]}]