@article{54943,
  abstract     = {{Proteolytic activation is a unique feature of the epithelial sodium channel (ENaC). However, the underlying molecular mechanisms and the physiologically relevant proteases remain to be identified. The serine protease trypsin I can activate ENaC in vitro but is unlikely to be the physiologically relevant activating protease in ENaC-expressing tissues in vivo. Herein, we investigated whether human trypsin IV, a form of trypsin that is co-expressed in several extrapancreatic epithelial cells with ENaC, can activate human ENaC. In Xenopus laevis oocytes, we monitored proteolytic activation of ENaC currents and the appearance of $\gamma$ENaC cleavage products at the cell surface. We demonstrated that trypsin IV and trypsin I can stimulate ENaC heterologously expressed in oocytes. ENaC cleavage and activation by trypsin IV but not by trypsin I required a critical cleavage site (Lys-189) in the extracellular domain of the $\gamma$-subunit. In contrast, channel activation by trypsin I was prevented by mutating three putative cleavage sites (Lys-168, Lys-170, and Arg-172) in addition to mutating previously described prostasin (RKRK(178)), plasmin (Lys-189), and neutrophil elastase (Val-182 and Val-193) sites. Moreover, we found that trypsin IV is expressed in human renal epithelial cells and can increase ENaC-mediated sodium transport in cultured human airway epithelial cells. Thus, trypsin IV may regulate ENaC function in epithelial tissues. Our results show, for the first time, that trypsin IV can stimulate ENaC and that trypsin IV and trypsin I activate ENaC by cleavage at distinct sites. The presence of distinct cleavage sites may be important for ENaC regulation by tissue-specific proteases.}},
  author       = {{Haerteis, Silke and Krappitz, Annabel and Krappitz, Matteus and Murphy, Jane E. and Bertog, Marko and Krueger, Bettina and Nacken, Regina and Chung, Hyunjae and Hollenberg, Morley D. and Knecht, Wolfgang and Bunnett, Nigel W. and Korbmacher, Christoph}},
  journal      = {{Journal of Biological Chemistry}},
  number       = {{27}},
  pages        = {{19067–19078}},
  publisher    = {{Elsevier}},
  title        = {{{Proteolytic Activation of the Human Epithelial Sodium Channel by Trypsin IV and Trypsin I Involves Distinct Cleavage Sites}}},
  doi          = {{10.1074/jbc.m113.538470}},
  volume       = {{289}},
  year         = {{2014}},
}

@article{40219,
  author       = {{Wagenknecht, Inga and Meier-Gräwe, Uta}},
  issn         = {{1616-8836}},
  journal      = {{Zeitschrift für Paar-, Familien- und Sozialtherapie}},
  number       = {{2}},
  pages        = {{91--108}},
  publisher    = {{Psychosozial-Verlag}},
  title        = {{{Auf- und Ausbau Früher Hilfen in Zeiten knapper öffentlicher Kassen. Warum es sich lohnt, in Frühe Hilfen zu investieren}}},
  volume       = {{15}},
  year         = {{2014}},
}

@article{22957,
  abstract     = {{We show, by means of numerical and analytical methods, that media with a repulsive nonlinearity which grows from the center to the periphery support a remarkable variety of previously unknown complex stationary and dynamical three-dimensional (3D) solitary-wave states. Peanut-shaped modulation profiles give rise to vertically symmetric and antisymmetric vortex states, and novel stationary hybrid states, built of top and bottom vortices with opposite topological charges, as well as robust dynamical hybrids, which feature stable precession of a vortex on top of a zero-vorticity soliton. The analysis reveals stability regions for symmetric, antisymmetric, and hybrid states. In addition, bead-shaped modulation profiles give rise to the first example of exact analytical solutions for stable 3D vortex solitons. The predicted states may be realized in media with a controllable cubic nonlinearity, such as Bose–Einstein condensates.}},
  author       = {{Driben, Rodislav and Kartashov, Yaroslav V. and Malomed, Boris A. and Meier, Torsten and Torner, Lluis}},
  issn         = {{1367-2630}},
  journal      = {{New Journal of Physics}},
  title        = {{{Three-dimensional hybrid vortex solitons}}},
  doi          = {{10.1088/1367-2630/16/6/063035}},
  volume       = {{16}},
  year         = {{2014}},
}

@inproceedings{39494,
  author       = {{Kanwar, Kelash and Mager, Thomas and Hilleringmann, Ulrich and Geneiss, Volker and Hedayat, Christian}},
  booktitle    = {{2014 IEEE RFID Technology and Applications Conference (RFID-TA)}},
  publisher    = {{IEEE}},
  title        = {{{Embedded UHF RFID tag design process for rubber transmission belt using 3D model}}},
  doi          = {{10.1109/rfid-ta.2014.6934208}},
  year         = {{2014}},
}

@article{22955,
  abstract     = {{The dynamics of 3D Airy-vortex wave packets is studied under the action of strong self-focusing Kerr nonlinearity. Emissions of nonlinear 3D waves out of the main wave packets with the topological charges were demonstrated. Because of the conservation of the total angular momentum, charges of the emitted waves are equal to those carried by the parental light structure. The rapid collapse imposes a severe limitation on the propagation of multidimensional waves in Kerr media. However, the structure of the Airy beam carrier allows the coupling of light from the leading, most intense peak into neighboring peaks and consequently strongly postpones the collapse. The dependence of the critical input amplitude for the appearance of a fast collapse on the beam width is studied for wave packets with zero and nonzero topological charges. Wave packets carrying angular momentum are found to be much more resistant to the rapid collapse.}},
  author       = {{Driben, Rodislav and Meier, Torsten}},
  issn         = {{0146-9592}},
  journal      = {{Optics Letters}},
  number       = {{19}},
  pages        = {{5539--5542}},
  title        = {{{Nonlinear dynamics of Airy-vortex 3D wave packets: emission of vortex light waves}}},
  doi          = {{10.1364/ol.39.005539}},
  volume       = {{39}},
  year         = {{2014}},
}

@inproceedings{29028,
  abstract     = {{In the last couple of years the amount of structured open government data has increased significantly. Already now, citizens are able to leverage the advantages of open data through increased transparency and better opportunities to take part in governmental decision making processes. Our approach increases the interoperability of existing but distributed open governmental datasets by converting them to the RDF-based NLP Interchange Format (NIF). Furthermore, we integrate the converted data into a geodata store and present a user interface for querying this data via a keyword-based search. The language resource generated in this project is publicly available for download and via a dedicated SPARQL endpoint.}},
  author       = {{Sherif, Mohamed and Coelho, Sandro and Usbeck, Ricardo and Hellmann, Sebastian and Lehmann, Jens and Brümmer, Martin and Both, Andreas}},
  booktitle    = {{The 9th edition of the Language Resources and Evaluation Conference, 26-31 May, Reykjavik, Iceland}},
  keywords     = {{2014 dice simba sherif sys:relevantFor:infai sys:relevantFor:bis sys:relevantFor:geoknow hellmann kilt lehmann usbeck bruemmer nif4oggd group\_aksw kilt Lidmole MOLE}},
  title        = {{{NIF4OGGD - NLP Interchange Format for Open German Governmental Data}}},
  year         = {{2014}},
}

@inproceedings{56527,
  author       = {{Merz, Dorian and Peñaloza, Rafael and Turhan, Anni-Yasmin}},
  booktitle    = {{KI 2014: Advances in Artificial Intelligence - 37th Annual German Conference on AI, Stuttgart, Germany, September 22-26, 2014. Proceedings}},
  editor       = {{Lutz, Carsten and Thielscher, Michael}},
  pages        = {{171–182}},
  publisher    = {{Springer}},
  title        = {{{Reasoning in \emphALC with Fuzzy Concrete Domains}}},
  doi          = {{10.1007/978-3-319-11206-0_17}},
  volume       = {{8736}},
  year         = {{2014}},
}

@inbook{25625,
  abstract     = {{After big disasters, search and rescue missions take place. During these missions it is essential to obtain an overview of the overall situation to arrange efficient rescue tasks as soon as possible. Afterwards, this information has to be continuously updated during the complete mission in order to quickly respond to changing conditions. The use of unmanned aerial vehicles (UAVs) is a viable choice to obtain such an overview in a fast and efficient way. Using multiple UAVs, the problem of coordination has to be solved to decrease the time needed to explore an area. We present an approach for the coordination of UAVs by setting up formation patterns using bifurcation theory. We combine this theory with a potential field approach for exploration, based on harmonic functions.}},
  author       = {{Rasche, Christoph and Stern, Claudius and Kleinjohann, Lisa and Kleinjohann, Bernd}},
  booktitle    = {{Recent Advances in Robotics and Automation, Studies in Computational Intelligence, Band 480}},
  editor       = {{Sen Gupta, Gourab and Bailey, Donald and Demidenko, Serge and Carnegie, Dale}},
  pages        = {{103--113}},
  publisher    = {{Springer }},
  title        = {{{A 3D Path Planning Approach Extended by Bifurcation Theory for Formation Flights}}},
  volume       = {{480}},
  year         = {{2013}},
}

@article{19981,
  author       = {{Mertsching, Bärbel and Divband Soorati, Mohammad and Kotthauser, Tobias}},
  journal      = {{IEEE International Conference on Robotics and Biomimetics (ROBIO)}},
  pages        = {{661--667}},
  title        = {{{Automatic Reconstruction of Polygonal Room Models from 3D Point Clouds}}},
  year         = {{2013}},
}

@article{26910,
  abstract     = {{<jats:p>Non-alcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and obesity. Hence, carbohydrate quality could be of relevance to the risk of NAFLD, but prospective data are lacking. The aim of the present study was to investigate longitudinal associations between carbohydrate quality (including dietary glycaemic index (GI) and intakes of sugar, starch and fibre) and markers of liver function in an older Australian population. The analysis was based on 866 participants ( ≥ 49 years) of the Blue Mountains Eye Study with fasting blood specimens and dietary intake data at baseline and 5-year follow-up. Multi-level mixed regression analysis was used to relate dietary GI and sugar, starch and fibre intake to the liver enzymes alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT), as well as fasting TAG and HDL-cholesterol (HDL-C). After adjustment for potential confounding factors, a lower fibre intake was cross-sectionally related to higher GGT (<jats:italic>P</jats:italic>= 0·02) and fasting TAG (<jats:italic>P</jats:italic>= 0·002) levels, with fruit fibre being the most relevant fibre source (<jats:italic>P</jats:italic>= 0·095 for GGT; <jats:italic>P</jats:italic>= 0·003 for TAG). A higher dietary GI was associated with lower HDL-C (<jats:italic>P</jats:italic>= 0·046). Changes in carbohydrate quality during 5 years were not related to changes in ALT, GGT, TAG or HDL-C (<jats:italic>P</jats:italic>≥ 0·08). In conclusion, the absence of longitudinal associations between carbohydrate quality and liver enzymes and serum lipids in this older population does not support a major role of carbohydrate nutrition in liver function among the elderly.</jats:p>}},
  author       = {{Goletzke, Janina and Buyken, Anette and Gopinath, Bamini and Rochtchina, Elena and Barclay, Alan W. and Cheng, Guo and Brand-Miller, Jennie C. and Mitchell, Paul}},
  issn         = {{0007-1145}},
  journal      = {{British Journal of Nutrition}},
  pages        = {{918--925}},
  title        = {{{Carbohydrate quality is not associated with liver enzyme activity and plasma TAG and HDL concentrations over 5 years in an older population}}},
  doi          = {{10.1017/s0007114512005867}},
  year         = {{2013}},
}

@article{26911,
  author       = {{Goletzke, J. and Herder, C. and Joslowski, G. and Bolzenius, K. and Remer, T. and Wudy, S. A. and Roden, M. and Rathmann, W. and Buyken, Anette}},
  issn         = {{0149-5992}},
  journal      = {{Diabetes Care}},
  pages        = {{1870--1876}},
  title        = {{{Habitually Higher Dietary Glycemic Index During Puberty Is Prospectively Related to Increased Risk Markers of Type 2 Diabetes in Younger Adulthood}}},
  doi          = {{10.2337/dc12-2063}},
  year         = {{2013}},
}

@article{26912,
  author       = {{Joslowski, Gesa and Remer, Thomas and Assmann, Karen E. and Krupp, Danika and Cheng, Guo and Garnett, Sarah P. and Kroke, Anja and Wudy, Stefan A. and Günther, Anke L. B. and Buyken, Anette}},
  issn         = {{1541-6100}},
  journal      = {{The Journal of Nutrition}},
  pages        = {{1147--1154}},
  title        = {{{Animal Protein Intakes during Early Life and Adolescence Differ in Their Relation to the Growth Hormone-Insulin-Like-Growth-Factor Axis in Young Adulthood}}},
  doi          = {{10.3945/jn.113.175877}},
  year         = {{2013}},
}

@article{27043,
  abstract     = {{<jats:p>Dietary fat intake in childhood may influence the risk for developing chronic diseases. The objective of the present study was to examine secular trends in the parameters of fat intake between 2000 and 2010 in a sample of German children and adolescents (<jats:italic>n</jats:italic> 808) participating in the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study. Dietary data from 4380 3 d weighed dietary records were analysed using repeated-measures regression to determine time trends in fat quantity, i.e. the intake of total fat, and in fat quality, i.e. the ratios of SFA, MUFA and PUFA. In young children (2–3 years) and in adolescents (13–18 years), total fat intake remained stable over time, but decreased by 0·08 % of total energy (%E) per year in 4–12-year-old children. In 2010, median fat intake was at the upper end of the recommendations. SFA intake decreased slightly in 2–3- and 4–12-year-old children by 0·09 and 0·05 %E per year, respectively. MUFA and PUFA intakes remained stable in all the age groups except in adolescents. Here, PUFA intake decreased initially, but increased between 2005 and 2010. In 2010, only between 3 and 18 % of the respective age groups had an intake of SFA or PUFA within the recommendations. In conclusion, fat quantity and quality did not change substantially between 2000 and 2010. Fat quality, in particular, needs to be improved, since a large percentage of our sample did not meet the recommended intakes for SFA and PUFA.</jats:p>}},
  author       = {{Libuda, Lars and Alexy, Ute and Kersting, Mathilde}},
  issn         = {{0007-1145}},
  journal      = {{British Journal of Nutrition}},
  pages        = {{141--150}},
  title        = {{{Time trends in dietary fat intake in a sample of German children and adolescents between 2000 and 2010: not quantity, but quality is the issue}}},
  doi          = {{10.1017/s0007114513002031}},
  year         = {{2013}},
}

@article{27061,
  author       = {{Libuda, Lars and Stimming, Madlen and Mesch, Christina and Warschburger, Petra and Kalhoff, Hermann and Koletzko, Berthold Viktor and Kersting, Mathilde}},
  issn         = {{1436-6207}},
  journal      = {{European Journal of Nutrition}},
  pages        = {{1335--1344}},
  title        = {{{Frequencies and demographic determinants of breastfeeding and DHA supplementation in a nationwide sample of mothers in Germany}}},
  doi          = {{10.1007/s00394-013-0633-4}},
  year         = {{2013}},
}

@article{27062,
  author       = {{Müller, Katrin and Libuda, Lars and Diethelm, Katharina and Huybrechts, Inge and Moreno, Luis A. and Manios, Yannis and Mistura, Lorenza and Dallongeville, Jean and Kafatos, Anthony and González-Gross, Marcela and Cuenca-García, Magdalena and Sjöström, Michael and Hallström, Lena and Widhalm, Kurt and Kersting, Mathilde}},
  issn         = {{0195-6663}},
  journal      = {{Appetite}},
  pages        = {{332--339}},
  title        = {{{Lunch at school, at home or elsewhere. Where do adolescents usually get it and what do they eat? Results of the HELENA Study}}},
  doi          = {{10.1016/j.appet.2013.09.002}},
  year         = {{2013}},
}

@article{27063,
  author       = {{Müller, K and Libuda, Lars and Gawehn, N and Drossard, C and Bolzenius, K and Kunz, C and Kersting, M}},
  issn         = {{0954-3007}},
  journal      = {{European Journal of Clinical Nutrition}},
  pages        = {{185--189}},
  title        = {{{Effects of lunch on children’s short-term cognitive functioning: a randomized crossover study}}},
  doi          = {{10.1038/ejcn.2012.209}},
  year         = {{2013}},
}

@article{27514,
  author       = {{Oepping, Anke and Schlegel-Matthies, Kirsten}},
  journal      = {{Schule NRW. Amtsblatt des Ministeriums für Schule und Weiterbildung}},
  pages        = {{10 -- 12}},
  title        = {{{Bildung für nachhaltige Entwicklung. Den Alltag gestalten – Teilhabe ermöglichen. Verbraucherbildung als Aufgabe von Schule}}},
  volume       = {{2}},
  year         = {{2013}},
}

@article{27515,
  author       = {{Schlegel-Matthies, Kirsten}},
  journal      = {{Haushalt in Bildung und Forschung (HiBiFo)}},
  number       = {{2}},
  pages        = {{61 -- 70}},
  title        = {{{Ethik, Konsumentenverantwortung und Verbraucherbildung im Spannungsfeld}}},
  volume       = {{2}},
  year         = {{2013}},
}

@article{27516,
  author       = {{Schlegel-Matthies, Kirsten}},
  journal      = {{Haushalt in Bildung und Forschung (HiBiFo)}},
  number       = {{2}},
  title        = {{{Fachliche Betreuung des Schwerpunktthemas: Ethik – Konsum – Verbraucherbildung. }}},
  volume       = {{2}},
  year         = {{2013}},
}

@book{27518,
  author       = {{Oepping, Anke and Schlegel-Matthies, Kirsten}},
  title        = {{{Ernährungs- und Verbraucherbildung im Unterricht }}},
  year         = {{2013}},
}

