@article{30118, abstract = {{Zusammenfassung Einleitung Im Rahmen der Demenz vom Alzheimer-Typ (DAT) zeigt sich eine gestörte neuronale Netzwerkorganisation, welche sich unter anderem auch im Default Mode Netzwerk (DMN) widerspiegelt. Multimodale Interventionen, wie zum Beispiel Golf, können einen positiven Einfluss auf die funktionelle Integrität der Netzwerke haben. Methodik Im Rahmen einer Pilotstudie wurde der Einfluss des Erlernens der Sportart Golf bei sieben älteren Menschen (> 60 Jahre) mit subjektiven Gedächtnisbeschwerden auf die funktionelle Konnektivität des DMN untersucht. Die Probanden haben 22 Wochen unter Anleitung eines professionellen Golftrainers dreimal wöchentlich je 60 min trainiert. Vor (Messzeitpunkt 0, MZP0) und nach der Intervention (Messzeitpunkt 1, MZP1) wurde eine Elektroenzephalografie (EEG)-Messung unter Ruhebedingungen (resting-state) durchgeführt. Die EEG-Daten wurden mit einem Magnetresonanztomographie-Template koregistriert. Die Konnektivitätsanalyse wurde in 15 Regionen des DMN durchgeführt und im Längsschnitt verglichen. Dabei wurden die Frequenzbänder beta (14–29 Hz) und theta (5–7 Hz) berücksichtigt. Ergebnisse Nach der Intervention wurde eine höhere funktionelle Konnektivität im gesamten DMN bei 5 / 7 Teilnehmenden im beta Frequenzband bzw. bei 6 / 7 Probanden im theta Frequenzband zu MZP1 im Vergleich zu MZP0 gemessen. Im anterioren DMN war bei allen Probanden und Probandinnen die funktionelle Konnektivität im beta Frequenzband zu MZP1 im Vergleich zu MZP 0 höher, während sie im theta-Band bei 6 von 7 Teilnehmenden niedriger war. Im posterioren DMN war bei 6 von 7 (beta), bzw. 5 von 7 (theta) Probanden und Probandinnen die funktionelle Konnektivität zu MZP1 höher als zu MZP0. Spearman-Korrelationsanalysen zeigen zudem einen Zusammenhang zwischen der Teilnahmehäufigkeit und der prozentualen Veränderung der funktionellen Konnektivität im gesamten DMN des beta Frequenzbandes (r = 0,786, p = 0,036) und im anterioren DMN des theta Frequenzbandes (r = –0,821, p = 0,023). Fazit Auf Basis der vorliegenden Daten lässt sich vermuten, dass das Erlernen der Sportart Golf einen Einfluss auf das DMN haben könnte. Die Ergebnisse bilden die Grundlage für die Planung einer Studie mit einer größeren Kohorte und randomisierten kontrollierten Design.}}, author = {{Ströhlein, Julia Kristin and Vieluf, Solveig and van den Bongard, Franziska and Gölz, Christian Johannes and Reinsberger, Claus}}, issn = {{1613-0863}}, journal = {{B&G Bewegungstherapie und Gesundheitssport}}, number = {{02}}, pages = {{65--72}}, publisher = {{Georg Thieme Verlag KG}}, title = {{{Golf spielen gegen die Vergesslichkeit: Effekte des Erlernens der Sportart auf das Default Mode Netzwerk des Gehirns}}}, doi = {{10.1055/a-1120-7002}}, volume = {{36}}, year = {{2020}}, } @article{22266, author = {{Grabo, Matti and Staggenborg, Christoph and Philippi, Kai Alexander and Kenig, Eugeny}}, issn = {{2296-598X}}, journal = {{Frontiers in Energy Research}}, title = {{{Modeling and Optimization of Rectangular Latent Heat Storage Elements in an Air-Guided Heat Storage System}}}, doi = {{10.3389/fenrg.2020.571787}}, volume = {{8}}, year = {{2020}}, } @article{45126, abstract = {{Abstract Purpose It has been reported that there is no correlation between anterior tibia translation (ATT) in passive and dynamic situations. Passive ATT (ATTp) may be different to dynamic ATT (ATTd) due to muscle activation patterns. This study aimed to investigate whether muscle activation during jumping can control ATT in healthy participants. Methods ATTp of twenty-one healthy participants was measured using a KT-1000 arthrometer. All participants performed single leg hops for distance during which ATTd, knee flexion angles and knee flexion moments were measured using a 3D motion capture system. During both tests, sEMG signals were recorded. Results A negative correlation was found between ATTp and the maximal ATTd (r = − 0.47, p = 0.028). An N-Way ANOVA showed that larger semitendinosus activity was seen when ATTd was larger, while less biceps femoris activity and rectus femoris activity were seen. Moreover, larger knee extension moment, knee flexion angle and ground reaction force in the anterior-posterior direction were seen when ATTd was larger. Conclusion Participants with more ATTp showed smaller ATTd during jump landing. Muscle activation did not contribute to reduce ATTd during impact of a jump-landing at the observed knee angles. However, subjects with large ATTp landed with less knee flexion and consequently showed less ATTd. The results of this study give information on how healthy people control knee laxity during jump-landing. Level of evidence III }}, author = {{Keizer, Michèle N. J. and Hijmans, Juha M. and Gokeler, Alli and Benjaminse, Anne and Otten, Egbert}}, issn = {{2197-1153}}, journal = {{Journal of Experimental Orthopaedics}}, keywords = {{Orthopedics and Sports Medicine}}, number = {{1}}, publisher = {{Springer Science and Business Media LLC}}, title = {{{Healthy subjects with lax knees use less knee flexion rather than muscle control to limit anterior tibia translation during landing}}}, doi = {{10.1186/s40634-020-00246-6}}, volume = {{7}}, year = {{2020}}, } @misc{42298, author = {{N., N.}}, publisher = {{Universität Paderborn}}, title = {{{Productivity optimization through project matching}}}, year = {{2020}}, } @book{45662, author = {{Lutz, Katharina and Offergeld, Jana and Freymuth, Nina and Arp, Anna Liza}}, title = {{{Gemeinsam Forschung gestalten. Handreichung zu partizipativer Forschung}}}, year = {{2020}}, } @inproceedings{17706, author = {{Schemmel, Reinhard and Krieger, Viktor and Hemsel, Tobias and Sextro, Walter}}, booktitle = {{2020 21st International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems (EuroSimE)}}, isbn = {{9781728160498}}, title = {{{Co-simulation of MATLAB and ANSYS for ultrasonic wire bonding process optimization}}}, doi = {{10.1109/eurosime48426.2020.9152679}}, year = {{2020}}, } @inproceedings{21632, abstract = {{FPGAs have found increasing adoption in data center applications since a new generation of high-level tools have become available which noticeably reduce development time for FPGA accelerators and still provide high-quality results. There is, however, no high-level benchmark suite available, which specifically enables a comparison of FPGA architectures, programming tools, and libraries for HPC applications. To fill this gap, we have developed an OpenCL-based open-source implementation of the HPCC benchmark suite for Xilinx and Intel FPGAs. This benchmark can serve to analyze the current capabilities of FPGA devices, cards, and development tool flows, track progress over time, and point out specific difficulties for FPGA acceleration in the HPC domain. Additionally, the benchmark documents proven performance optimization patterns. We will continue optimizing and porting the benchmark for new generations of FPGAs and design tools and encourage active participation to create a valuable tool for the community. To fill this gap, we have developed an OpenCL-based open-source implementation of the HPCC benchmark suite for Xilinx and Intel FPGAs. This benchmark can serve to analyze the current capabilities of FPGA devices, cards, and development tool flows, track progress over time, and point out specific difficulties for FPGA acceleration in the HPC domain. Additionally, the benchmark documents proven performance optimization patterns. We will continue optimizing and porting the benchmark for new generations of FPGAs and design tools and encourage active participation to create a valuable tool for the community.}}, author = {{Meyer, Marius and Kenter, Tobias and Plessl, Christian}}, booktitle = {{2020 IEEE/ACM International Workshop on Heterogeneous High-performance Reconfigurable Computing (H2RC)}}, isbn = {{9781665415927}}, keywords = {{FPGA, OpenCL, High Level Synthesis, HPC benchmarking}}, title = {{{Evaluating FPGA Accelerator Performance with a Parameterized OpenCL Adaptation of Selected Benchmarks of the HPCChallenge Benchmark Suite}}}, doi = {{10.1109/h2rc51942.2020.00007}}, year = {{2020}}, } @inproceedings{56490, author = {{Hieke, Willi and Turhan, Anni-Yasmin}}, booktitle = {{Proceedings of the 6th Workshop on Formal and Cognitive Reasoning co-located with 43rd German Conference on Artificial Intelligence (KI-2020), Online / Bamberg, Germany, September 22, 2020}}, editor = {{Beierle, Christoph and Ragni, Marco and Stolzenburg, Frieder and Thimm, Matthias}}, pages = {{69–82}}, publisher = {{CEUR-WS.org}}, title = {{{Towards Model Transformation in Description Logics - Investigating the Case of Transductions}}}, volume = {{2680}}, year = {{2020}}, } @article{63329, abstract = {{AbstractRecent experimental work has revealed that interstitial fluid flow can mobilize two types of tumor cell migration mechanisms. One is a chemotactic-driven mechanism where chemokine (chemical component) bounded to the extracellular matrix (ECM) is released and skewed in the flow direction. This leads to higher chemical concentrations downstream which the tumor cells can sense and migrate toward. The other is a mechanism where the flowing fluid imposes a stress on the tumor cells which triggers them to go in the upstream direction. Researchers have suggested that these two migration modes possibly can play a role in metastatic behavior, i.e., the process where tumor cells are able to break loose from the primary tumor and move to nearby lymphatic vessels. In Waldeland and Evje (J Biomech 81:22–35, 2018), a mathematical cell–fluid model was put forward based on a mixture theory formulation. It was demonstrated that the model was able to capture the main characteristics of the two competing migration mechanisms. The objective of the current work is to seek deeper insight into certain qualitative aspects of these competing mechanisms by means of mathematical methods. For that purpose, we propose a simpler version of the cell–fluid model mentioned above but such that the two competing migration mechanisms are retained. An initial cell distribution in a one-dimensional slab is exposed to a constant fluid flow from one end to the other, consistent with the experimental setup. Then, we explore by means of analytical estimates the long-time behavior of the two competing migration mechanisms for two different scenarios: (i) when the initial cell volume fraction is low and (ii) when the initial cell volume fraction is high. In particular, it is demonstrated in a strict mathematical sense that for a sufficiently low initial cell volume fraction, the downstream migration dominates in the sense that the solution converges to a downstream-dominated steady state as time elapses. On the other hand, with a sufficiently high initial cell volume fraction, the upstream migration mechanism is the stronger in the sense that the solution converges to an upstream-dominated steady state. }}, author = {{Evje, Steinar and Winkler, Michael}}, issn = {{0938-8974}}, journal = {{Journal of Nonlinear Science}}, number = {{4}}, pages = {{1809--1847}}, publisher = {{Springer Science and Business Media LLC}}, title = {{{Mathematical Analysis of Two Competing Cancer Cell Migration Mechanisms Driven by Interstitial Fluid Flow}}}, doi = {{10.1007/s00332-020-09625-w}}, volume = {{30}}, year = {{2020}}, } @article{60383, abstract = {{AbstractThe problem of seamless parametrization of surfaces is of interest in the context of structured quadrilateral mesh generation and spline‐based surface approximation. It has been tackled by a variety of approaches, commonly relying on continuous numerical optimization to ultimately obtain suitable parameter domains. We present a general combinatorial seamless parameter domain construction, free from the potential numerical issues inherent to continuous optimization techniques in practice. The domains are constructed as abstract polygonal complexes which can be embedded in a discrete planar grid space, as unions of unit squares. We ensure that the domain structure matches any prescribed parametrization singularities (cones) and satisfies seamlessness conditions. Surfaces of arbitrary genus are supported. Once a domain suitable for a given surface is constructed, a seamless and locally injective parametrization over this domain can be obtained using existing planar disk mapping techniques, making recourse to Tutte's classical embedding theorem.}}, author = {{Zhou, Jiaran and Tu, Changhe and Zorin, Denis and Campen, Marcel}}, issn = {{0167-7055}}, journal = {{Computer Graphics Forum}}, number = {{2}}, pages = {{179--190}}, publisher = {{Wiley}}, title = {{{Combinatorial Construction of Seamless Parameter Domains}}}, doi = {{10.1111/cgf.13922}}, volume = {{39}}, year = {{2020}}, } @article{21420, author = {{Mair, Christina and Scheffler, Wolfram and Senger, Isabell and Sureth-Sloane, Caren}}, journal = {{Steuer und Wirtschaft}}, number = {{4}}, pages = {{317--329}}, title = {{{Auswirkungen der digitalen Flexibilisierung des Fertigungsortes auf die Verteilung der Besteuerungsrechte – Ergebnisse von Modellrechnungen zum 3D-Druck-Verfahren}}}, volume = {{97}}, year = {{2020}}, } @article{67000, author = {{Matthiesen, Bho and Hellings, Christoph and Jorswieck, Eduard A. and Utschick, Wolfgang}}, issn = {{1053-587X}}, journal = {{IEEE Transactions on Signal Processing}}, pages = {{2529--2544}}, publisher = {{Institute of Electrical and Electronics Engineers (IEEE)}}, title = {{{Mixed Monotonic Programming for Fast Global Optimization}}}, doi = {{10.1109/tsp.2020.2983284}}, volume = {{68}}, year = {{2020}}, } @inproceedings{25617, author = {{Schöppner, Volker and Sporkmann, F.}}, booktitle = {{35th International Conference of the Polymer Processing Society (PPS)}}, location = {{Cesme (Türkei)}}, title = {{{Analysis of the Characteristic Flow Areas for Erdmenger-Elements to Predict the Throughput-Pressure Behavior of Co-Rotating Twin Screw Extruders by Using 3D FEM Simulation}}}, year = {{2019}}, } @misc{28364, author = {{Gausemeier, Jürgen}}, isbn = {{978-3-947647-09-5}}, publisher = {{Verlagsschriftenreihe des Heinz Nixdorf Instituts, Paderborn}}, title = {{{Vorausschau und Technologieplanung. 15. Symposium für Vorausschau und Technologieplanung, Heinz Nixdorf Institut, 21. und 22. November 2019}}}, volume = {{390}}, year = {{2019}}, } @inproceedings{24058, abstract = {{Embedded systems require a high energy efficiency in combination with an optimized performance. As such, Bit Manipulation Instructions (BMIs) were introduced for x86 and ARMv8 to improve the runtime efficiency and power dissipation of the compiled software for various applications. Though the RISC-V platform is meanwhile widely accepted for embedded systems application, its instruction set architecture (ISA) currently still supports only two basic BMIs.We introduce ten advanced BMIs for the RISC-V ISA and implemented them on Berkeley's Rocket CPU [1], which we synthesized for the Artix-7 FPGA and the TSMC 65nm cell library. Our RISC-V BMI definitions are based on an analysis and combination of existing x86 and ARMv8 BMIs. Our Rocket CPU hardware extensions show that RISC-V BMI extensions have no negative impact on the critical path of the execution pipeline. Our software evaluations show that we can, for example, expect a significant impact for time and power consuming cryptographic applications.}}, author = {{Koppelmann, Bastian and Adelt, Peer and Müller, Wolfgang and Scheytt, Christoph}}, booktitle = {{29th International Symposium on Power and Timing Modeling, Optimization and Simulation (PATMOS)}}, title = {{{RISC-V Extensions for Bit Manipulation Instructions}}}, doi = {{10.1109/PATMOS.2019.8862170}}, year = {{2019}}, } @inproceedings{24060, abstract = {{In diesem Artikel stellen wir eine Methode zur nicht-invasiven dynamischen Speicher- und IO-Analyse mit QEMU für sicherheitskritische eingebettete Software für die RISC-V Befehlssatzarchitektur vor. Die Implementierung basiert auf einer Erweiterung des Tiny Code Generator (TCG) des quelloffenen CPU-Emulators QEMU um die dynamische Identifikation von Zugriffen auf Datenspeicher sowie auf an die CPU angeschlossene IO-Geräte. Wir demonstrieren die Funktionalität der Methode anhand eines Versuchsaufbaus, bei dem eine Schließsystemkontrolle mittels serieller UART-Schnittstelle an einen RISC-V-Prozessor angebunden ist. Dieses Szenario zeigt, dass ein unberechtigter Zugriff auf die UART-Schnittstelle frühzeitig aufgedeckt und ein Angriff auf eine Zugangskontrolle somit endeckt werden kann. }}, author = {{Adelt, Peer and Koppelmann, Bastian and Müller, Wolfgang and Scheytt, Christoph}}, booktitle = {{MBMV 2019-22.Workshop Methoden und Beschreibungssprachen zur Modellierung und Verifikation von Schaltungen und Systemen (MBMV 2019)}}, isbn = {{978-3-8007-4945-4}}, title = {{{Analyse sicherheitskritischer Software für RISC-V Prozessoren}}}, year = {{2019}}, } @inproceedings{24502, abstract = {{Liquid atomization is expected to be a key process in Flame Spray Pyrolysis, as it determines the primary droplet size and velocity distribution, which represent initial conditions for flame shape and temperature field. A well-defined manipulation of atomization may be achieved by variation of nozzle geometry, injection parameter or fluid properties. However, change of fluid properties, e.g. varying solvents or increasing the precursor concentration, also influences the final particle properties. In this work, the influence of precursor concentration on fluid properties, spray and particle formation in Flame Spray Pyrolysis is experimentally investigated. High-speed shadowgraphy and Phase-Doppler measurements are conducted in a semi-closed combustion chamber with a well-defined burner geometry (SpraySyn burner) that is based on a coaxial atomization principle. By adding precursor to the flammable solvent, resulting spray characteristics, flame shape and appearance are changed in color, shape and mean droplet size distribution. Compared to resulting mean droplet sizes of pure solvent mixtures (D32, 22 μm), mean droplet sizes in the center of the precursor flame at 30 mm above the burner are generally smaller (D32, 18 μm). Persisting high share of small droplets in the droplet size distribution are presented, that presumably origin from an accumulation of metal organic precursor at the droplet surface during combustion, that acts as a diffusive barrier for high volatility solvent and thus reduces droplet evaporation. Sufficiently high above the nozzle exit, increasing the precursor concentration does not affect the radial distribution of mean droplet sizes but leads to increased mean particle sizes. More precursor presumably leads to higher concentrations of prime particles in the flame, thus probability of particle collusion and agglomeration. High-speed imaging at nozzle exit revealed random fluctuations of initial jet diameter, paired with jet axis shifting around 1000 Hz. These superposed fluctuations determine the initial conditions for atomization, induce pulsations in the flame and thus initiate the entire chain of the particle synthesis process.}}, author = {{Bieber, M. and Tischendorf, R. and Reddemann, M. and Schmid, H.-J. and Kneer, R.}}, keywords = {{FSP, nanoparticle synthesis, in situ measurements}}, location = {{Paris}}, publisher = {{ILASS (European Conference on Liquid Atomization and Spray Systems)}}, title = {{{Influence of precursor concentration on spray and particle formation in flame spray pyrolysis}}}, year = {{2019}}, } @article{24632, abstract = {{Prerequisite for an efficient cooling energy system is the knowledge and optimal combination of different operating conditions of individual compression and free cooling chillers. The performance of cooling systems depends on their part-load performance and their condensing temperature, which are often not continuously measured. Recorded energy data remain unused, and manufacturers’ data differ from the real performance. For this purpose, manufacturer and real data are combined and continuously adapted to form part-load chiller models. This study applied a predictive optimization algorithm to calculate the optimal operating conditions of multiple chillers. A sprinkler tank offers the opportunity to store cold-water for later utilization. This potential is used to show the load shifting potential of the cooling system by using a variable electricity price as an input variable to the optimization. The set points from the optimization have been continuously adjusted throughout a dynamic simulation. A case study of a plastic processing company evaluates different scenarios against the status quo. Applying an optimal chiller sequencing and charging strategy of a sprinkler tank leads to electrical energy savings of up to 43%. Purchasing electricity on the EPEX SPOT market leads to additional costs savings of up to 17%. The total energy savings highly depend on the weather conditions and the prediction horizon.}}, author = {{Peesel, Ron-Hendrik and Schlosser, Florian and Meschede, Henning and Dunkelberg, Heiko and Walmsley, Timothy}}, issn = {{1996-1073}}, journal = {{Energies}}, title = {{{Optimization of Cooling Utility System with Continuous Self-Learning Performance Models}}}, doi = {{10.3390/en12101926}}, year = {{2019}}, } @inproceedings{25755, author = {{Moritzer, Elmar and Wittke, M.}}, booktitle = {{77th Annual Technical Conference of the Society of Plastics Engineers (ANTEC)}}, location = {{Detroit (USA)}}, title = {{{Simulation-based Optimization of Advanced Mixing Elements on Single Screw Extruders}}}, year = {{2019}}, } @article{27003, author = {{Perrar, Ines and Schmitting, Sarah and Della Corte, Karen W. and Buyken, Anette and Alexy, Ute}}, issn = {{1436-6207}}, journal = {{European Journal of Nutrition}}, pages = {{1043--1054}}, title = {{{Age and time trends in sugar intake among children and adolescents: results from the DONALD study}}}, doi = {{10.1007/s00394-019-01965-y}}, year = {{2019}}, }