--- _id: '61335' abstract: - lang: eng text: Amidines are a ubiquitous class of bioactive compounds found in a wide variety of natural products; thus, efficient strategies for their preparation are in great demand. Herein, a novel protocol is reported for the synthesis of amidines based on PIII/PVO redox catalysis. This two‐step, one‐pot approach involves the activation of amides via PIII/PVO catalyzed in situ formation of imidoyl chloride intermediates which are directly converted upon reaction with amines into the corresponding amidines. Instead of traditionally used toxic and corrosive chloride sources, hexachloroacetone (HCA) is successfully employed as a halide source. The reaction proceeds with low catalyst loading (2 mol%) in BuOAc as the solvent. Under the optimized conditions, 20 amidines are prepared in yields up to 99%. A feasible mechanism is proposed based on experimental results. The synthetic potential of this method is evaluated in the preparation of the tyrosine kinase inhibitor (TKI) Erlotinib. article_number: '202500394' author: - first_name: Viktorija full_name: Medvaric, Viktorija id: '92677' last_name: Medvaric - first_name: Jan full_name: Paradies, Jan id: '53339' last_name: Paradies orcid: 0000-0002-3698-668X - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Medvaric V, Paradies J, Werner T. Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides. Advanced Synthesis and Catalysis. Published online 2025. doi:10.1002/adsc.70059 apa: Medvaric, V., Paradies, J., & Werner, T. (2025). Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides. Advanced Synthesis and Catalysis, Article 202500394. https://doi.org/10.1002/adsc.70059 bibtex: '@article{Medvaric_Paradies_Werner_2025, title={Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides}, DOI={10.1002/adsc.70059}, number={202500394}, journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Medvaric, Viktorija and Paradies, Jan and Werner, Thomas}, year={2025} }' chicago: Medvaric, Viktorija, Jan Paradies, and Thomas Werner. “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides.” Advanced Synthesis and Catalysis, 2025. https://doi.org/10.1002/adsc.70059. ieee: 'V. Medvaric, J. Paradies, and T. Werner, “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides,” Advanced Synthesis and Catalysis, Art. no. 202500394, 2025, doi: 10.1002/adsc.70059.' mla: Medvaric, Viktorija, et al. “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides.” Advanced Synthesis and Catalysis, 202500394, Wiley, 2025, doi:10.1002/adsc.70059. short: V. Medvaric, J. Paradies, T. Werner, Advanced Synthesis and Catalysis (2025). date_created: 2025-09-17T15:16:49Z date_updated: 2025-11-10T08:44:04Z department: - _id: '2' - _id: '389' doi: 10.1002/adsc.70059 keyword: - T2 - T - CSSD language: - iso: eng publication: Advanced Synthesis and Catalysis publication_identifier: issn: - 1615-4150 - 1615-4169 publication_status: published publisher: Wiley status: public title: Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides type: journal_article user_id: '89271' year: '2025' ... --- _id: '62086' author: - first_name: Vivian full_name: Stefanow, Vivian last_name: Stefanow - first_name: Lukas full_name: Kell, Lukas last_name: Kell - first_name: Aiga full_name: Leduskrasta, Aiga last_name: Leduskrasta - first_name: Marcus full_name: Eh, Marcus last_name: Eh - first_name: Johannes full_name: Panten, Johannes last_name: Panten - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Stefanow V, Kell L, Leduskrasta A, Eh M, Panten J, Werner T. Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients. The Journal of Organic Chemistry. 2025;90(37):12877-12887. doi:10.1021/acs.joc.5c00889 apa: Stefanow, V., Kell, L., Leduskrasta, A., Eh, M., Panten, J., & Werner, T. (2025). Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients. The Journal of Organic Chemistry, 90(37), 12877–12887. https://doi.org/10.1021/acs.joc.5c00889 bibtex: '@article{Stefanow_Kell_Leduskrasta_Eh_Panten_Werner_2025, title={Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients}, volume={90}, DOI={10.1021/acs.joc.5c00889}, number={37}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Stefanow, Vivian and Kell, Lukas and Leduskrasta, Aiga and Eh, Marcus and Panten, Johannes and Werner, Thomas}, year={2025}, pages={12877–12887} }' chicago: 'Stefanow, Vivian, Lukas Kell, Aiga Leduskrasta, Marcus Eh, Johannes Panten, and Thomas Werner. “Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients.” The Journal of Organic Chemistry 90, no. 37 (2025): 12877–87. https://doi.org/10.1021/acs.joc.5c00889.' ieee: 'V. Stefanow, L. Kell, A. Leduskrasta, M. Eh, J. Panten, and T. Werner, “Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients,” The Journal of Organic Chemistry, vol. 90, no. 37, pp. 12877–12887, 2025, doi: 10.1021/acs.joc.5c00889.' mla: Stefanow, Vivian, et al. “Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients.” The Journal of Organic Chemistry, vol. 90, no. 37, American Chemical Society (ACS), 2025, pp. 12877–87, doi:10.1021/acs.joc.5c00889. short: V. Stefanow, L. Kell, A. Leduskrasta, M. Eh, J. Panten, T. Werner, The Journal of Organic Chemistry 90 (2025) 12877–12887. date_created: 2025-11-05T15:10:13Z date_updated: 2025-11-10T08:43:33Z department: - _id: '35' - _id: '2' doi: 10.1021/acs.joc.5c00889 intvolume: ' 90' issue: '37' keyword: - T4 - CSSD language: - iso: eng page: 12877-12887 publication: The Journal of Organic Chemistry publication_identifier: issn: - 0022-3263 - 1520-6904 publication_status: published publisher: American Chemical Society (ACS) status: public title: Straightforward Access to Terpene-Based 1,2-Diols and Their Acetals as Fragrance Ingredients type: journal_article user_id: '89271' volume: 90 year: '2025' ... --- _id: '61336' article_number: jacs.5c06190 author: - first_name: Rundong full_name: Zhou, Rundong last_name: Zhou - first_name: Viktorija full_name: Medvaric, Viktorija id: '92677' last_name: Medvaric - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: https://orcid.org/0000-0001-9025-3244 - first_name: Jan full_name: Paradies, Jan id: '53339' last_name: Paradies orcid: 0000-0002-3698-668X citation: ama: 'Zhou R, Medvaric V, Werner T, Paradies J. Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance. Journal of the American Chemical Society. Published online 2025. doi:10.1021/jacs.5c06190' apa: 'Zhou, R., Medvaric, V., Werner, T., & Paradies, J. (2025). Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance. Journal of the American Chemical Society, Article jacs. 5c06190. https://doi.org/10.1021/jacs.5c06190' bibtex: '@article{Zhou_Medvaric_Werner_Paradies_2025, title={Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance}, DOI={10.1021/jacs.5c06190}, number={jacs. 5c06190}, journal={Journal of the American Chemical Society}, publisher={American Chemical Society (ACS)}, author={Zhou, Rundong and Medvaric, Viktorija and Werner, Thomas and Paradies, Jan}, year={2025} }' chicago: 'Zhou, Rundong, Viktorija Medvaric, Thomas Werner, and Jan Paradies. “Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance.” Journal of the American Chemical Society, 2025. https://doi.org/10.1021/jacs.5c06190.' ieee: 'R. Zhou, V. Medvaric, T. Werner, and J. Paradies, “Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance,” Journal of the American Chemical Society, Art. no. jacs. 5c06190, 2025, doi: 10.1021/jacs.5c06190.' mla: 'Zhou, Rundong, et al. “Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance.” Journal of the American Chemical Society, jacs. 5c06190, American Chemical Society (ACS), 2025, doi:10.1021/jacs.5c06190.' short: R. Zhou, V. Medvaric, T. Werner, J. Paradies, Journal of the American Chemical Society (2025). date_created: 2025-09-17T15:18:11Z date_updated: 2025-11-10T08:43:50Z department: - _id: '2' - _id: '389' doi: 10.1021/jacs.5c06190 keyword: - T2 - CSSD language: - iso: eng publication: Journal of the American Chemical Society publication_identifier: issn: - 0002-7863 - 1520-5126 publication_status: published publisher: American Chemical Society (ACS) status: public title: 'Metal-Free Reduction of Nitrous Oxide via P^III/P^V═O Cycling: Mechanistic Insights and Catalytic Performance' type: journal_article user_id: '89271' year: '2025' ... --- _id: '62090' abstract: - lang: eng text: The selective N-formylation and N-methylation of amines with carbon dioxide (CO2) catalyzed by methyltriphenylphosphonium methylcarbonate and tuned by polymethylhydrosiloxane or trimethoxysilane as reducing agents is reported. author: - first_name: Changyue full_name: Ren, Changyue last_name: Ren - first_name: Constanza full_name: Terazzi, Constanza last_name: Terazzi - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Ren C, Terazzi C, Werner T. Tuneable reduction of CO₂ – organocatalyzed selective formylation and methylation of amines. Green Chemistry. 2024;26(1):439-447. doi:10.1039/d3gc03993e apa: Ren, C., Terazzi, C., & Werner, T. (2024). Tuneable reduction of CO₂ – organocatalyzed selective formylation and methylation of amines. Green Chemistry, 26(1), 439–447. https://doi.org/10.1039/d3gc03993e bibtex: '@article{Ren_Terazzi_Werner_2024, title={Tuneable reduction of CO₂ – organocatalyzed selective formylation and methylation of amines}, volume={26}, DOI={10.1039/d3gc03993e}, number={1}, journal={Green Chemistry}, publisher={Royal Society of Chemistry (RSC)}, author={Ren, Changyue and Terazzi, Constanza and Werner, Thomas}, year={2024}, pages={439–447} }' chicago: 'Ren, Changyue, Constanza Terazzi, and Thomas Werner. “Tuneable Reduction of CO₂ – Organocatalyzed Selective Formylation and Methylation of Amines.” Green Chemistry 26, no. 1 (2024): 439–47. https://doi.org/10.1039/d3gc03993e.' ieee: 'C. Ren, C. Terazzi, and T. Werner, “Tuneable reduction of CO₂ – organocatalyzed selective formylation and methylation of amines,” Green Chemistry, vol. 26, no. 1, pp. 439–447, 2024, doi: 10.1039/d3gc03993e.' mla: Ren, Changyue, et al. “Tuneable Reduction of CO₂ – Organocatalyzed Selective Formylation and Methylation of Amines.” Green Chemistry, vol. 26, no. 1, Royal Society of Chemistry (RSC), 2024, pp. 439–47, doi:10.1039/d3gc03993e. short: C. Ren, C. Terazzi, T. Werner, Green Chemistry 26 (2024) 439–447. date_created: 2025-11-05T15:16:32Z date_updated: 2025-11-10T08:44:44Z department: - _id: '35' - _id: '2' doi: 10.1039/d3gc03993e intvolume: ' 26' issue: '1' keyword: - T1 - T2 - CSSD language: - iso: eng page: 439-447 publication: Green Chemistry publication_identifier: issn: - 1463-9262 - 1463-9270 publication_status: published publisher: Royal Society of Chemistry (RSC) status: public title: Tuneable reduction of CO₂ – organocatalyzed selective formylation and methylation of amines type: journal_article user_id: '89271' volume: 26 year: '2024' ... --- _id: '62091' author: - first_name: Changyue full_name: Ren, Changyue last_name: Ren - first_name: Anke full_name: Spannenberg, Anke last_name: Spannenberg - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Ren C, Spannenberg A, Werner T. Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂. ACS Sustainable Chemistry & Engineering. 2024;12(29):10969-10977. doi:10.1021/acssuschemeng.4c03464 apa: Ren, C., Spannenberg, A., & Werner, T. (2024). Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂. ACS Sustainable Chemistry & Engineering, 12(29), 10969–10977. https://doi.org/10.1021/acssuschemeng.4c03464 bibtex: '@article{Ren_Spannenberg_Werner_2024, title={Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂}, volume={12}, DOI={10.1021/acssuschemeng.4c03464}, number={29}, journal={ACS Sustainable Chemistry & Engineering}, publisher={American Chemical Society (ACS)}, author={Ren, Changyue and Spannenberg, Anke and Werner, Thomas}, year={2024}, pages={10969–10977} }' chicago: 'Ren, Changyue, Anke Spannenberg, and Thomas Werner. “Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂.” ACS Sustainable Chemistry & Engineering 12, no. 29 (2024): 10969–77. https://doi.org/10.1021/acssuschemeng.4c03464.' ieee: 'C. Ren, A. Spannenberg, and T. Werner, “Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂,” ACS Sustainable Chemistry & Engineering, vol. 12, no. 29, pp. 10969–10977, 2024, doi: 10.1021/acssuschemeng.4c03464.' mla: Ren, Changyue, et al. “Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂.” ACS Sustainable Chemistry & Engineering, vol. 12, no. 29, American Chemical Society (ACS), 2024, pp. 10969–77, doi:10.1021/acssuschemeng.4c03464. short: C. Ren, A. Spannenberg, T. Werner, ACS Sustainable Chemistry & Engineering 12 (2024) 10969–10977. date_created: 2025-11-05T15:17:55Z date_updated: 2025-11-10T08:45:58Z department: - _id: '35' - _id: '2' doi: 10.1021/acssuschemeng.4c03464 intvolume: ' 12' issue: '29' keyword: - T1 - T2 - CSSD language: - iso: eng page: 10969-10977 publication: ACS Sustainable Chemistry & Engineering publication_identifier: issn: - 2168-0485 - 2168-0485 publication_status: published publisher: American Chemical Society (ACS) status: public title: Phosphonium-Salt-Catalyzed N-Methylation and N-Formylation of Amines with CO₂ type: journal_article user_id: '89271' volume: 12 year: '2024' ... --- _id: '62088' author: - first_name: Jan full_name: Tönjes, Jan last_name: Tönjes - first_name: Viktorija full_name: Medvarić, Viktorija last_name: Medvarić - first_name: Thomas full_name: Werner, Thomas last_name: Werner citation: ama: Tönjes J, Medvarić V, Werner T. Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis. The Journal of Organic Chemistry. 2024;89(15):10729-10735. doi:10.1021/acs.joc.4c00985 apa: Tönjes, J., Medvarić, V., & Werner, T. (2024). Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis. The Journal of Organic Chemistry, 89(15), 10729–10735. https://doi.org/10.1021/acs.joc.4c00985 bibtex: '@article{Tönjes_Medvarić_Werner_2024, title={Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis}, volume={89}, DOI={10.1021/acs.joc.4c00985}, number={15}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Tönjes, Jan and Medvarić, Viktorija and Werner, Thomas}, year={2024}, pages={10729–10735} }' chicago: 'Tönjes, Jan, Viktorija Medvarić, and Thomas Werner. “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis.” The Journal of Organic Chemistry 89, no. 15 (2024): 10729–35. https://doi.org/10.1021/acs.joc.4c00985.' ieee: 'J. Tönjes, V. Medvarić, and T. Werner, “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis,” The Journal of Organic Chemistry, vol. 89, no. 15, pp. 10729–10735, 2024, doi: 10.1021/acs.joc.4c00985.' mla: Tönjes, Jan, et al. “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis.” The Journal of Organic Chemistry, vol. 89, no. 15, American Chemical Society (ACS), 2024, pp. 10729–35, doi:10.1021/acs.joc.4c00985. short: J. Tönjes, V. Medvarić, T. Werner, The Journal of Organic Chemistry 89 (2024) 10729–10735. date_created: 2025-11-05T15:12:46Z date_updated: 2025-11-10T08:45:17Z department: - _id: '35' - _id: '2' doi: 10.1021/acs.joc.4c00985 intvolume: ' 89' issue: '15' keyword: - T2 - CSSD language: - iso: eng page: 10729-10735 publication: The Journal of Organic Chemistry publication_identifier: issn: - 0022-3263 - 1520-6904 publication_status: published publisher: American Chemical Society (ACS) status: public title: Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis type: journal_article user_id: '89271' volume: 89 year: '2024' ... --- _id: '62096' abstract: - lang: eng text: AbstractThe biocatalytic kinetic resolution of cyclic carbonates derived from glycerol is reported. A selection of 26 esterases and lipases was tested for the asymmetric hydrolysis of the model substrate (epichlorohydrin carbonate) in aqueous medium. Among them, Pig Liver Esterase and Novozym® 435 showed the best selectivity with E=38 and 49, respectively. Both enzymes were employed for the conversion of 12 glycerol derivatives under optimized conditions. The resolution of halogenated carbonates afforded the unconverted enantiomer in up to >99 : 1 er. Furthermore, Novozym® 435 was successfully recycled 10 times without significant loss of activity. Upscaling and isolation of the chiral carbonate was also demonstrated. Subsequent conversion of this chiral building block allowed the direct one‐pot synthesis of (S)‐Guaifenesin, (S)‐Mephenesin and (S)‐Chlorphenesin in up to 89 % yield and 94 : 6 er. article_number: e202300917 author: - first_name: Constanza full_name: Terazzi, Constanza last_name: Terazzi - first_name: Anke full_name: Spannenberg, Anke last_name: Spannenberg - first_name: Jan full_name: von Langermann, Jan last_name: von Langermann - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Terazzi C, Spannenberg A, von Langermann J, Werner T. Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates. ChemCatChem. 2023;15(19). doi:10.1002/cctc.202300917 apa: Terazzi, C., Spannenberg, A., von Langermann, J., & Werner, T. (2023). Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates. ChemCatChem, 15(19), Article e202300917. https://doi.org/10.1002/cctc.202300917 bibtex: '@article{Terazzi_Spannenberg_von Langermann_Werner_2023, title={Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates}, volume={15}, DOI={10.1002/cctc.202300917}, number={19e202300917}, journal={ChemCatChem}, publisher={Wiley}, author={Terazzi, Constanza and Spannenberg, Anke and von Langermann, Jan and Werner, Thomas}, year={2023} }' chicago: Terazzi, Constanza, Anke Spannenberg, Jan von Langermann, and Thomas Werner. “Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates.” ChemCatChem 15, no. 19 (2023). https://doi.org/10.1002/cctc.202300917. ieee: 'C. Terazzi, A. Spannenberg, J. von Langermann, and T. Werner, “Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates,” ChemCatChem, vol. 15, no. 19, Art. no. e202300917, 2023, doi: 10.1002/cctc.202300917.' mla: Terazzi, Constanza, et al. “Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates.” ChemCatChem, vol. 15, no. 19, e202300917, Wiley, 2023, doi:10.1002/cctc.202300917. short: C. Terazzi, A. Spannenberg, J. von Langermann, T. Werner, ChemCatChem 15 (2023). date_created: 2025-11-05T15:23:21Z date_updated: 2025-11-10T08:46:22Z department: - _id: '35' - _id: '2' doi: 10.1002/cctc.202300917 intvolume: ' 15' issue: '19' keyword: - T1 - T4 - CSSD language: - iso: eng publication: ChemCatChem publication_identifier: issn: - 1867-3880 - 1867-3899 publication_status: published publisher: Wiley status: public title: Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol‐Derived Cyclic Carbonates type: journal_article user_id: '89271' volume: 15 year: '2023' ... --- _id: '62095' author: - first_name: Jan full_name: Tönjes, Jan last_name: Tönjes - first_name: Lukas full_name: Kell, Lukas last_name: Kell - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Tönjes J, Kell L, Werner T. Organocatalytic Stereospecific Appel Reaction. Organic Letters. 2023;25(51):9114-9118. doi:10.1021/acs.orglett.3c03463 apa: Tönjes, J., Kell, L., & Werner, T. (2023). Organocatalytic Stereospecific Appel Reaction. Organic Letters, 25(51), 9114–9118. https://doi.org/10.1021/acs.orglett.3c03463 bibtex: '@article{Tönjes_Kell_Werner_2023, title={Organocatalytic Stereospecific Appel Reaction}, volume={25}, DOI={10.1021/acs.orglett.3c03463}, number={51}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Tönjes, Jan and Kell, Lukas and Werner, Thomas}, year={2023}, pages={9114–9118} }' chicago: 'Tönjes, Jan, Lukas Kell, and Thomas Werner. “Organocatalytic Stereospecific Appel Reaction.” Organic Letters 25, no. 51 (2023): 9114–18. https://doi.org/10.1021/acs.orglett.3c03463.' ieee: 'J. Tönjes, L. Kell, and T. Werner, “Organocatalytic Stereospecific Appel Reaction,” Organic Letters, vol. 25, no. 51, pp. 9114–9118, 2023, doi: 10.1021/acs.orglett.3c03463.' mla: Tönjes, Jan, et al. “Organocatalytic Stereospecific Appel Reaction.” Organic Letters, vol. 25, no. 51, American Chemical Society (ACS), 2023, pp. 9114–18, doi:10.1021/acs.orglett.3c03463. short: J. Tönjes, L. Kell, T. Werner, Organic Letters 25 (2023) 9114–9118. date_created: 2025-11-05T15:22:44Z date_updated: 2025-11-10T08:46:39Z department: - _id: '35' - _id: '2' doi: 10.1021/acs.orglett.3c03463 intvolume: ' 25' issue: '51' keyword: - T2 - CSSD language: - iso: eng page: 9114-9118 publication: Organic Letters publication_identifier: issn: - 1523-7060 - 1523-7052 publication_status: published publisher: American Chemical Society (ACS) status: public title: Organocatalytic Stereospecific Appel Reaction type: journal_article user_id: '89271' volume: 25 year: '2023' ... --- _id: '37938' author: - first_name: Constanza full_name: Terazzi, Constanza last_name: Terazzi - first_name: Karoline full_name: Laatz, Karoline last_name: Laatz - first_name: Jan full_name: von Langermann, Jan last_name: von Langermann - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Terazzi C, Laatz K, von Langermann J, Werner T. Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution. ACS Sustainable Chemistry and Engineering. 2022;10(40):13335-13342. doi:10.1021/acssuschemeng.2c03210 apa: Terazzi, C., Laatz, K., von Langermann, J., & Werner, T. (2022). Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution. ACS Sustainable Chemistry and Engineering, 10(40), 13335–13342. https://doi.org/10.1021/acssuschemeng.2c03210 bibtex: '@article{Terazzi_Laatz_von Langermann_Werner_2022, title={Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution}, volume={10}, DOI={10.1021/acssuschemeng.2c03210}, number={40}, journal={ACS Sustainable Chemistry and Engineering}, publisher={American Chemical Society (ACS)}, author={Terazzi, Constanza and Laatz, Karoline and von Langermann, Jan and Werner, Thomas}, year={2022}, pages={13335–13342} }' chicago: 'Terazzi, Constanza, Karoline Laatz, Jan von Langermann, and Thomas Werner. “Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution.” ACS Sustainable Chemistry and Engineering 10, no. 40 (2022): 13335–42. https://doi.org/10.1021/acssuschemeng.2c03210.' ieee: 'C. Terazzi, K. Laatz, J. von Langermann, and T. Werner, “Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution,” ACS Sustainable Chemistry and Engineering, vol. 10, no. 40, pp. 13335–13342, 2022, doi: 10.1021/acssuschemeng.2c03210.' mla: Terazzi, Constanza, et al. “Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution.” ACS Sustainable Chemistry and Engineering, vol. 10, no. 40, American Chemical Society (ACS), 2022, pp. 13335–42, doi:10.1021/acssuschemeng.2c03210. short: C. Terazzi, K. Laatz, J. von Langermann, T. Werner, ACS Sustainable Chemistry and Engineering 10 (2022) 13335–13342. date_created: 2023-01-22T20:10:44Z date_updated: 2025-11-10T08:47:07Z department: - _id: '2' - _id: '657' doi: 10.1021/acssuschemeng.2c03210 intvolume: ' 10' issue: '40' keyword: - T1 - T3 - CSSD language: - iso: eng page: 13335-13342 publication: ACS Sustainable Chemistry and Engineering publication_identifier: issn: - 2168-0485 - 2168-0485 publication_status: published publisher: American Chemical Society (ACS) status: public title: Synthesis of Cyclic Carbonates Catalyzed by CaI₂–Et₃N and Studies on Their Biocatalytic Kinetic Resolution type: journal_article user_id: '89271' volume: 10 year: '2022' ... --- _id: '37940' author: - first_name: Changyue full_name: Ren, Changyue last_name: Ren - first_name: Anke full_name: Spannenberg, Anke last_name: Spannenberg - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Ren C, Spannenberg A, Werner T. Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂. Asian Journal of Organic Chemistry. 2022;11(9). doi:10.1002/ajoc.202200156 apa: Ren, C., Spannenberg, A., & Werner, T. (2022). Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂. Asian Journal of Organic Chemistry, 11(9). https://doi.org/10.1002/ajoc.202200156 bibtex: '@article{Ren_Spannenberg_Werner_2022, title={Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂}, volume={11}, DOI={10.1002/ajoc.202200156}, number={9}, journal={Asian Journal of Organic Chemistry}, publisher={Wiley}, author={Ren, Changyue and Spannenberg, Anke and Werner, Thomas}, year={2022} }' chicago: Ren, Changyue, Anke Spannenberg, and Thomas Werner. “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂.” Asian Journal of Organic Chemistry 11, no. 9 (2022). https://doi.org/10.1002/ajoc.202200156. ieee: 'C. Ren, A. Spannenberg, and T. Werner, “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂,” Asian Journal of Organic Chemistry, vol. 11, no. 9, 2022, doi: 10.1002/ajoc.202200156.' mla: Ren, Changyue, et al. “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂.” Asian Journal of Organic Chemistry, vol. 11, no. 9, Wiley, 2022, doi:10.1002/ajoc.202200156. short: C. Ren, A. Spannenberg, T. Werner, Asian Journal of Organic Chemistry 11 (2022). date_created: 2023-01-22T20:19:21Z date_updated: 2025-11-10T08:47:20Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1002/ajoc.202200156 intvolume: ' 11' issue: '9' keyword: - T1 - T2 - CSSD language: - iso: eng publication: Asian Journal of Organic Chemistry publication_identifier: issn: - 2193-5807 - 2193-5815 publication_status: published publisher: Wiley status: public title: Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO ₂ type: journal_article user_id: '89271' volume: 11 year: '2022' ... --- _id: '37946' abstract: - lang: eng text: AbstractThe facile synthesis of highly functionalized building blocks with potential biological activity is of great interest to medicinal chemistry. The benzoxepinone core structures commonly exhibit biological activity. Thus, a short and efficient synthetic route towards benzoxepine containing scaffold, which enables late stage modification was developed. Namely, base-free catalytic Wittig reactions enabled the synthesis of bromobenzoxepinones from readily available starting materials. Subsequent, Suzuki–Miyaura and Stille reactions proved to be suitable methods to access a variety of benzoxepinone diaryl derivatives by late stage modification in only three steps. This three-step reaction sequence is suitable for high throughput applications and gives facile access to highly complex molecular structures, which are suitable for further functionalization. The antiproliferative properties of selected arylbenzoxepinones were tested in vitro on monolayer tumor cell line A549. Notably, in this initial screening, these compounds were found to be active in the micromolar range. author: - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 - first_name: Aiga full_name: Grandane, Aiga last_name: Grandane - first_name: Linda full_name: Pudnika, Linda last_name: Pudnika - first_name: Ilona full_name: Domraceva, Ilona last_name: Domraceva - first_name: Raivis full_name: Zalubovskis, Raivis last_name: Zalubovskis citation: ama: Werner T, Grandane A, Pudnika L, Domraceva I, Zalubovskis R. Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones. Synthesis. 2021;53(19):3545-3554. doi:10.1055/a-1509-6078 apa: Werner, T., Grandane, A., Pudnika, L., Domraceva, I., & Zalubovskis, R. (2021). Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones. Synthesis, 53(19), 3545–3554. https://doi.org/10.1055/a-1509-6078 bibtex: '@article{Werner_Grandane_Pudnika_Domraceva_Zalubovskis_2021, title={Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones}, volume={53}, DOI={10.1055/a-1509-6078}, number={19}, journal={Synthesis}, publisher={Georg Thieme Verlag KG}, author={Werner, Thomas and Grandane, Aiga and Pudnika, Linda and Domraceva, Ilona and Zalubovskis, Raivis}, year={2021}, pages={3545–3554} }' chicago: 'Werner, Thomas, Aiga Grandane, Linda Pudnika, Ilona Domraceva, and Raivis Zalubovskis. “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones.” Synthesis 53, no. 19 (2021): 3545–54. https://doi.org/10.1055/a-1509-6078.' ieee: 'T. Werner, A. Grandane, L. Pudnika, I. Domraceva, and R. Zalubovskis, “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones,” Synthesis, vol. 53, no. 19, pp. 3545–3554, 2021, doi: 10.1055/a-1509-6078.' mla: Werner, Thomas, et al. “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones.” Synthesis, vol. 53, no. 19, Georg Thieme Verlag KG, 2021, pp. 3545–54, doi:10.1055/a-1509-6078. short: T. Werner, A. Grandane, L. Pudnika, I. Domraceva, R. Zalubovskis, Synthesis 53 (2021) 3545–3554. date_created: 2023-01-22T20:27:34Z date_updated: 2025-11-10T08:47:47Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1055/a-1509-6078 intvolume: ' 53' issue: '19' keyword: - T2 - T4 - CSSD language: - iso: eng page: 3545-3554 publication: Synthesis publication_identifier: issn: - 0039-7881 - 1437-210X publication_status: published publisher: Georg Thieme Verlag KG status: public title: Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones type: journal_article user_id: '89271' volume: 53 year: '2021' ... --- _id: '37944' abstract: - lang: eng text:

A Mn–PNP complex proved to be a suitable catalyst for the transfer hydrogenation of amides, carbamates, urea derivatives and even polyurethanes.

author: - first_name: Xin full_name: Liu, Xin last_name: Liu - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: https://orcid.org/0000-0001-9025-3244 citation: ama: Liu X, Werner T. Indirect reduction of CO₂ and recycling of polymers by manganese-catalyzed transfer hydrogenation of amides, carbamates, urea derivatives, and polyurethanes. Chemical Science. 2021;12(31):10590-10597. doi:10.1039/d1sc02663a apa: Liu, X., & Werner, T. (2021). Indirect reduction of CO₂ and recycling of polymers by manganese-catalyzed transfer hydrogenation of amides, carbamates, urea derivatives, and polyurethanes. Chemical Science, 12(31), 10590–10597. https://doi.org/10.1039/d1sc02663a bibtex: '@article{Liu_Werner_2021, title={Indirect reduction of CO₂ and recycling of polymers by manganese-catalyzed transfer hydrogenation of amides, carbamates, urea derivatives, and polyurethanes}, volume={12}, DOI={10.1039/d1sc02663a}, number={31}, journal={Chemical Science}, publisher={Royal Society of Chemistry (RSC)}, author={Liu, Xin and Werner, Thomas}, year={2021}, pages={10590–10597} }' chicago: 'Liu, Xin, and Thomas Werner. “Indirect Reduction of CO₂ and Recycling of Polymers by Manganese-Catalyzed Transfer Hydrogenation of Amides, Carbamates, Urea Derivatives, and Polyurethanes.” Chemical Science 12, no. 31 (2021): 10590–97. https://doi.org/10.1039/d1sc02663a.' ieee: 'X. Liu and T. Werner, “Indirect reduction of CO₂ and recycling of polymers by manganese-catalyzed transfer hydrogenation of amides, carbamates, urea derivatives, and polyurethanes,” Chemical Science, vol. 12, no. 31, pp. 10590–10597, 2021, doi: 10.1039/d1sc02663a.' mla: Liu, Xin, and Thomas Werner. “Indirect Reduction of CO₂ and Recycling of Polymers by Manganese-Catalyzed Transfer Hydrogenation of Amides, Carbamates, Urea Derivatives, and Polyurethanes.” Chemical Science, vol. 12, no. 31, Royal Society of Chemistry (RSC), 2021, pp. 10590–97, doi:10.1039/d1sc02663a. short: X. Liu, T. Werner, Chemical Science 12 (2021) 10590–10597. date_created: 2023-01-22T20:24:03Z date_updated: 2025-11-10T08:49:01Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1039/d1sc02663a intvolume: ' 12' issue: '31' keyword: - T1 - T3 - CSSD language: - iso: eng page: 10590-10597 publication: Chemical Science publication_identifier: issn: - 2041-6520 - 2041-6539 publication_status: published publisher: Royal Society of Chemistry (RSC) status: public title: Indirect reduction of CO₂ and recycling of polymers by manganese-catalyzed transfer hydrogenation of amides, carbamates, urea derivatives, and polyurethanes type: journal_article user_id: '89271' volume: 12 year: '2021' ... --- _id: '37945' abstract: - lang: eng text:

PMHS proved to be a suitable terminal reductant for P(iii)/P(v) redox cycling with a methyl-substituted phosphetane as catalyst and BuOAc as solvent. The formation of water by silanol condensation was identified as main pathway of siloxane formation.

author: - first_name: Jan full_name: Tönjes, Jan last_name: Tönjes - first_name: Lars full_name: Longwitz, Lars last_name: Longwitz - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Tönjes J, Longwitz L, Werner T. Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction. Green Chemistry. 2021;23(13):4852-4857. doi:10.1039/d1gc00953b apa: Tönjes, J., Longwitz, L., & Werner, T. (2021). Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction. Green Chemistry, 23(13), 4852–4857. https://doi.org/10.1039/d1gc00953b bibtex: '@article{Tönjes_Longwitz_Werner_2021, title={Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction}, volume={23}, DOI={10.1039/d1gc00953b}, number={13}, journal={Green Chemistry}, publisher={Royal Society of Chemistry (RSC)}, author={Tönjes, Jan and Longwitz, Lars and Werner, Thomas}, year={2021}, pages={4852–4857} }' chicago: 'Tönjes, Jan, Lars Longwitz, and Thomas Werner. “Poly(Methylhydrosiloxane) as a Reductant in the Catalytic Base-Free Wittig Reaction.” Green Chemistry 23, no. 13 (2021): 4852–57. https://doi.org/10.1039/d1gc00953b.' ieee: 'J. Tönjes, L. Longwitz, and T. Werner, “Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction,” Green Chemistry, vol. 23, no. 13, pp. 4852–4857, 2021, doi: 10.1039/d1gc00953b.' mla: Tönjes, Jan, et al. “Poly(Methylhydrosiloxane) as a Reductant in the Catalytic Base-Free Wittig Reaction.” Green Chemistry, vol. 23, no. 13, Royal Society of Chemistry (RSC), 2021, pp. 4852–57, doi:10.1039/d1gc00953b. short: J. Tönjes, L. Longwitz, T. Werner, Green Chemistry 23 (2021) 4852–4857. date_created: 2023-01-22T20:25:13Z date_updated: 2025-11-10T08:48:01Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1039/d1gc00953b intvolume: ' 23' issue: '13' keyword: - T2 - CSSD language: - iso: eng page: 4852-4857 publication: Green Chemistry publication_identifier: issn: - 1463-9262 - 1463-9270 publication_status: published publisher: Royal Society of Chemistry (RSC) status: public title: Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction type: journal_article user_id: '89271' volume: 23 year: '2021' ... --- _id: '62098' author: - first_name: Vivian full_name: Stefanow, Vivian last_name: Stefanow - first_name: Aiga full_name: Grandane, Aiga last_name: Grandane - first_name: Marcus full_name: Eh, Marcus last_name: Eh - first_name: Johannes full_name: Panten, Johannes last_name: Panten - first_name: Anke full_name: Spannenberg, Anke last_name: Spannenberg - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Stefanow V, Grandane A, Eh M, Panten J, Spannenberg A, Werner T. Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant. Organic Process Research & Development. 2021;25(1):89-97. doi:10.1021/acs.oprd.0c00423 apa: Stefanow, V., Grandane, A., Eh, M., Panten, J., Spannenberg, A., & Werner, T. (2021). Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant. Organic Process Research & Development, 25(1), 89–97. https://doi.org/10.1021/acs.oprd.0c00423 bibtex: '@article{Stefanow_Grandane_Eh_Panten_Spannenberg_Werner_2021, title={Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant}, volume={25}, DOI={10.1021/acs.oprd.0c00423}, number={1}, journal={Organic Process Research & Development}, publisher={American Chemical Society (ACS)}, author={Stefanow, Vivian and Grandane, Aiga and Eh, Marcus and Panten, Johannes and Spannenberg, Anke and Werner, Thomas}, year={2021}, pages={89–97} }' chicago: 'Stefanow, Vivian, Aiga Grandane, Marcus Eh, Johannes Panten, Anke Spannenberg, and Thomas Werner. “Stereoselective Synthesis of aCis-Cedrane-8,9-Diol as a Key Intermediate for an Amber Odorant.” Organic Process Research & Development 25, no. 1 (2021): 89–97. https://doi.org/10.1021/acs.oprd.0c00423.' ieee: 'V. Stefanow, A. Grandane, M. Eh, J. Panten, A. Spannenberg, and T. Werner, “Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant,” Organic Process Research & Development, vol. 25, no. 1, pp. 89–97, 2021, doi: 10.1021/acs.oprd.0c00423.' mla: Stefanow, Vivian, et al. “Stereoselective Synthesis of aCis-Cedrane-8,9-Diol as a Key Intermediate for an Amber Odorant.” Organic Process Research & Development, vol. 25, no. 1, American Chemical Society (ACS), 2021, pp. 89–97, doi:10.1021/acs.oprd.0c00423. short: V. Stefanow, A. Grandane, M. Eh, J. Panten, A. Spannenberg, T. Werner, Organic Process Research & Development 25 (2021) 89–97. date_created: 2025-11-05T15:26:05Z date_updated: 2025-11-10T08:48:33Z department: - _id: '35' - _id: '2' doi: 10.1021/acs.oprd.0c00423 intvolume: ' 25' issue: '1' keyword: - T4 - CSSD language: - iso: eng page: 89-97 publication: Organic Process Research & Development publication_identifier: issn: - 1083-6160 - 1520-586X publication_status: published publisher: American Chemical Society (ACS) status: public title: Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant type: journal_article user_id: '89271' volume: 25 year: '2021' ... --- _id: '62099' author: - first_name: Vivian full_name: Stefanow, Vivian last_name: Stefanow - first_name: Aiga full_name: Grandane, Aiga last_name: Grandane - first_name: Marcus full_name: Eh, Marcus last_name: Eh - first_name: Johannes full_name: Panten, Johannes last_name: Panten - first_name: Anke full_name: Spannenberg, Anke last_name: Spannenberg - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Stefanow V, Grandane A, Eh M, Panten J, Spannenberg A, Werner T. Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant. Organic Process Research & Development. 2021;25(1):89-97. doi:10.1021/acs.oprd.0c00423 apa: Stefanow, V., Grandane, A., Eh, M., Panten, J., Spannenberg, A., & Werner, T. (2021). Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant. Organic Process Research & Development, 25(1), 89–97. https://doi.org/10.1021/acs.oprd.0c00423 bibtex: '@article{Stefanow_Grandane_Eh_Panten_Spannenberg_Werner_2021, title={Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant}, volume={25}, DOI={10.1021/acs.oprd.0c00423}, number={1}, journal={Organic Process Research & Development}, publisher={American Chemical Society (ACS)}, author={Stefanow, Vivian and Grandane, Aiga and Eh, Marcus and Panten, Johannes and Spannenberg, Anke and Werner, Thomas}, year={2021}, pages={89–97} }' chicago: 'Stefanow, Vivian, Aiga Grandane, Marcus Eh, Johannes Panten, Anke Spannenberg, and Thomas Werner. “Stereoselective Synthesis of aCis-Cedrane-8,9-Diol as a Key Intermediate for an Amber Odorant.” Organic Process Research & Development 25, no. 1 (2021): 89–97. https://doi.org/10.1021/acs.oprd.0c00423.' ieee: 'V. Stefanow, A. Grandane, M. Eh, J. Panten, A. Spannenberg, and T. Werner, “Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant,” Organic Process Research & Development, vol. 25, no. 1, pp. 89–97, 2021, doi: 10.1021/acs.oprd.0c00423.' mla: Stefanow, Vivian, et al. “Stereoselective Synthesis of aCis-Cedrane-8,9-Diol as a Key Intermediate for an Amber Odorant.” Organic Process Research & Development, vol. 25, no. 1, American Chemical Society (ACS), 2021, pp. 89–97, doi:10.1021/acs.oprd.0c00423. short: V. Stefanow, A. Grandane, M. Eh, J. Panten, A. Spannenberg, T. Werner, Organic Process Research & Development 25 (2021) 89–97. date_created: 2025-11-05T15:28:23Z date_updated: 2025-11-10T08:49:27Z department: - _id: '35' - _id: '2' doi: 10.1021/acs.oprd.0c00423 intvolume: ' 25' issue: '1' keyword: - T4 - CSSD language: - iso: eng page: 89-97 publication: Organic Process Research & Development publication_identifier: issn: - 1083-6160 - 1520-586X publication_status: published publisher: American Chemical Society (ACS) status: public title: Stereoselective Synthesis of acis-Cedrane-8,9-diol as a Key Intermediate for an Amber Odorant type: journal_article user_id: '89271' volume: 25 year: '2021' ... --- _id: '37943' article_number: '112768' author: - first_name: Marisa A. full_name: Wirth, Marisa A. last_name: Wirth - first_name: Lars full_name: Longwitz, Lars last_name: Longwitz - first_name: Marion full_name: Kanwischer, Marion last_name: Kanwischer - first_name: Peter full_name: Gros, Peter last_name: Gros - first_name: Peter full_name: Leinweber, Peter last_name: Leinweber - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: https://orcid.org/0000-0001-9025-3244 citation: ama: Wirth MA, Longwitz L, Kanwischer M, Gros P, Leinweber P, Werner T. AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate. Ecotoxicology and Environmental Safety. 2021;225. doi:10.1016/j.ecoenv.2021.112768 apa: Wirth, M. A., Longwitz, L., Kanwischer, M., Gros, P., Leinweber, P., & Werner, T. (2021). AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate. Ecotoxicology and Environmental Safety, 225, Article 112768. https://doi.org/10.1016/j.ecoenv.2021.112768 bibtex: '@article{Wirth_Longwitz_Kanwischer_Gros_Leinweber_Werner_2021, title={AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate}, volume={225}, DOI={10.1016/j.ecoenv.2021.112768}, number={112768}, journal={Ecotoxicology and Environmental Safety}, publisher={Elsevier BV}, author={Wirth, Marisa A. and Longwitz, Lars and Kanwischer, Marion and Gros, Peter and Leinweber, Peter and Werner, Thomas}, year={2021} }' chicago: Wirth, Marisa A., Lars Longwitz, Marion Kanwischer, Peter Gros, Peter Leinweber, and Thomas Werner. “AMPA-15N – Synthesis and Application as Standard Compound in Traceable Degradation Studies of Glyphosate.” Ecotoxicology and Environmental Safety 225 (2021). https://doi.org/10.1016/j.ecoenv.2021.112768. ieee: 'M. A. Wirth, L. Longwitz, M. Kanwischer, P. Gros, P. Leinweber, and T. Werner, “AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate,” Ecotoxicology and Environmental Safety, vol. 225, Art. no. 112768, 2021, doi: 10.1016/j.ecoenv.2021.112768.' mla: Wirth, Marisa A., et al. “AMPA-15N – Synthesis and Application as Standard Compound in Traceable Degradation Studies of Glyphosate.” Ecotoxicology and Environmental Safety, vol. 225, 112768, Elsevier BV, 2021, doi:10.1016/j.ecoenv.2021.112768. short: M.A. Wirth, L. Longwitz, M. Kanwischer, P. Gros, P. Leinweber, T. Werner, Ecotoxicology and Environmental Safety 225 (2021). date_created: 2023-01-22T20:23:06Z date_updated: 2025-11-10T08:48:20Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1016/j.ecoenv.2021.112768 intvolume: ' 225' keyword: - T4 - CSSD language: - iso: eng publication: Ecotoxicology and Environmental Safety publication_identifier: issn: - 0147-6513 publication_status: published publisher: Elsevier BV status: public title: AMPA-15N – Synthesis and application as standard compound in traceable degradation studies of glyphosate type: journal_article user_id: '89271' volume: 225 year: '2021' ... --- _id: '37948' author: - first_name: Xin full_name: Liu, Xin last_name: Liu - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: https://orcid.org/0000-0001-9025-3244 citation: ama: Liu X, Werner T. Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides. Advanced Synthesis and Catalysis. 2021;363(4):1096-1104. doi:10.1002/adsc.202001209 apa: Liu, X., & Werner, T. (2021). Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides. Advanced Synthesis and Catalysis, 363(4), 1096–1104. https://doi.org/10.1002/adsc.202001209 bibtex: '@article{Liu_Werner_2021, title={Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides}, volume={363}, DOI={10.1002/adsc.202001209}, number={4}, journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Liu, Xin and Werner, Thomas}, year={2021}, pages={1096–1104} }' chicago: 'Liu, Xin, and Thomas Werner. “Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides.” Advanced Synthesis and Catalysis 363, no. 4 (2021): 1096–1104. https://doi.org/10.1002/adsc.202001209.' ieee: 'X. Liu and T. Werner, “Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides,” Advanced Synthesis and Catalysis, vol. 363, no. 4, pp. 1096–1104, 2021, doi: 10.1002/adsc.202001209.' mla: Liu, Xin, and Thomas Werner. “Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides.” Advanced Synthesis and Catalysis, vol. 363, no. 4, Wiley, 2021, pp. 1096–104, doi:10.1002/adsc.202001209. short: X. Liu, T. Werner, Advanced Synthesis and Catalysis 363 (2021) 1096–1104. date_created: 2023-01-22T20:30:29Z date_updated: 2025-11-10T08:48:47Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1002/adsc.202001209 extern: '1' intvolume: ' 363' issue: '4' keyword: - T1 - T3 - CSSD language: - iso: eng page: 1096-1104 publication: Advanced Synthesis and Catalysis publication_identifier: issn: - 1615-4150 - 1615-4169 publication_status: published publisher: Wiley status: public title: Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides type: journal_article user_id: '89271' volume: 363 year: '2021' ... --- _id: '62102' abstract: - lang: eng text: AbstractThe carbon–carbon double bond of unsaturated carbonyl compounds was readily reduced by using a phosphetane oxide catalyst in the presence of a simple organosilane as the terminal reductant and water as the hydrogen source. Quantitative hydrogenation was observed when 1.0 mol % of a methyl‐substituted phosphetane oxide was employed as the catalyst. The procedure is highly selective towards activated double bonds, tolerating a variety of functional groups that are usually prone to reduction. In total, 25 alkenes and two alkynes were hydrogenated to the corresponding alkanes in excellent yields of up to 99 %. Notably, less active poly(methylhydrosiloxane) could also be utilized as the terminal reductant. Mechanistic investigations revealed the phosphane as the catalyst resting state and a protonation/deprotonation sequence as the crucial step in the catalytic cycle. author: - first_name: Lars full_name: Longwitz, Lars last_name: Longwitz - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Longwitz L, Werner T. Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis. Angewandte Chemie International Edition. 2020;59(7):2760-2763. doi:10.1002/anie.201912991 apa: Longwitz, L., & Werner, T. (2020). Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis. Angewandte Chemie International Edition, 59(7), 2760–2763. https://doi.org/10.1002/anie.201912991 bibtex: '@article{Longwitz_Werner_2020, title={Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis}, volume={59}, DOI={10.1002/anie.201912991}, number={7}, journal={Angewandte Chemie International Edition}, publisher={Wiley}, author={Longwitz, Lars and Werner, Thomas}, year={2020}, pages={2760–2763} }' chicago: 'Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis.” Angewandte Chemie International Edition 59, no. 7 (2020): 2760–63. https://doi.org/10.1002/anie.201912991.' ieee: 'L. Longwitz and T. Werner, “Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis,” Angewandte Chemie International Edition, vol. 59, no. 7, pp. 2760–2763, 2020, doi: 10.1002/anie.201912991.' mla: Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis.” Angewandte Chemie International Edition, vol. 59, no. 7, Wiley, 2020, pp. 2760–63, doi:10.1002/anie.201912991. short: L. Longwitz, T. Werner, Angewandte Chemie International Edition 59 (2020) 2760–2763. date_created: 2025-11-05T15:39:56Z date_updated: 2025-11-10T08:49:52Z department: - _id: '35' - _id: '2' doi: 10.1002/anie.201912991 intvolume: ' 59' issue: '7' keyword: - T2 - T4 - CSSD language: - iso: eng page: 2760-2763 publication: Angewandte Chemie International Edition publication_identifier: issn: - 1433-7851 - 1521-3773 publication_status: published publisher: Wiley status: public title: Reduction of Activated Alkenes by P^III/P^V Redox Cycling Catalysis type: journal_article user_id: '89271' volume: 59 year: '2020' ... --- _id: '37951' author: - first_name: Xin full_name: Liu, Xin last_name: Liu - first_name: Lars full_name: Longwitz, Lars last_name: Longwitz - first_name: Brian full_name: Spiegelberg, Brian last_name: Spiegelberg - first_name: Jan full_name: Tönjes, Jan last_name: Tönjes - first_name: Torsten full_name: Beweries, Torsten last_name: Beweries - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Liu X, Longwitz L, Spiegelberg B, Tönjes J, Beweries T, Werner T. Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions. ACS Catalysis. 2020;10(22):13659-13667. doi:10.1021/acscatal.0c03294 apa: Liu, X., Longwitz, L., Spiegelberg, B., Tönjes, J., Beweries, T., & Werner, T. (2020). Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions. ACS Catalysis, 10(22), 13659–13667. https://doi.org/10.1021/acscatal.0c03294 bibtex: '@article{Liu_Longwitz_Spiegelberg_Tönjes_Beweries_Werner_2020, title={Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions}, volume={10}, DOI={10.1021/acscatal.0c03294}, number={22}, journal={ACS Catalysis}, publisher={American Chemical Society (ACS)}, author={Liu, Xin and Longwitz, Lars and Spiegelberg, Brian and Tönjes, Jan and Beweries, Torsten and Werner, Thomas}, year={2020}, pages={13659–13667} }' chicago: 'Liu, Xin, Lars Longwitz, Brian Spiegelberg, Jan Tönjes, Torsten Beweries, and Thomas Werner. “Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions.” ACS Catalysis 10, no. 22 (2020): 13659–67. https://doi.org/10.1021/acscatal.0c03294.' ieee: 'X. Liu, L. Longwitz, B. Spiegelberg, J. Tönjes, T. Beweries, and T. Werner, “Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions,” ACS Catalysis, vol. 10, no. 22, pp. 13659–13667, 2020, doi: 10.1021/acscatal.0c03294.' mla: Liu, Xin, et al. “Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions.” ACS Catalysis, vol. 10, no. 22, American Chemical Society (ACS), 2020, pp. 13659–67, doi:10.1021/acscatal.0c03294. short: X. Liu, L. Longwitz, B. Spiegelberg, J. Tönjes, T. Beweries, T. Werner, ACS Catalysis 10 (2020) 13659–13667. date_created: 2023-01-22T20:35:25Z date_updated: 2025-11-10T08:50:10Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1021/acscatal.0c03294 extern: '1' intvolume: ' 10' issue: '22' keyword: - T3 - CSSD language: - iso: eng page: 13659-13667 publication: ACS Catalysis publication_identifier: issn: - 2155-5435 - 2155-5435 publication_status: published publisher: American Chemical Society (ACS) status: public title: Erbium-Catalyzed Regioselective Isomerization–Cobalt-Catalyzed Transfer Hydrogenation Sequence for the Synthesis of Anti-Markovnikov Alcohols from Epoxides under Mild Conditions type: journal_article user_id: '89271' volume: 10 year: '2020' ... --- _id: '37955' author: - first_name: Christoph full_name: Wulf, Christoph last_name: Wulf - first_name: Matthias full_name: Reckers, Matthias last_name: Reckers - first_name: Anna full_name: Perechodjuk, Anna last_name: Perechodjuk - first_name: Thomas full_name: Werner, Thomas id: '89271' last_name: Werner orcid: 0000-0001-9025-3244 citation: ama: Wulf C, Reckers M, Perechodjuk A, Werner T. Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes. ACS Sustainable Chemistry and Engineering. 2020;8(3):1651-1658. doi:10.1021/acssuschemeng.9b06662 apa: Wulf, C., Reckers, M., Perechodjuk, A., & Werner, T. (2020). Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes. ACS Sustainable Chemistry and Engineering, 8(3), 1651–1658. https://doi.org/10.1021/acssuschemeng.9b06662 bibtex: '@article{Wulf_Reckers_Perechodjuk_Werner_2020, title={Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes}, volume={8}, DOI={10.1021/acssuschemeng.9b06662}, number={3}, journal={ACS Sustainable Chemistry and Engineering}, publisher={American Chemical Society (ACS)}, author={Wulf, Christoph and Reckers, Matthias and Perechodjuk, Anna and Werner, Thomas}, year={2020}, pages={1651–1658} }' chicago: 'Wulf, Christoph, Matthias Reckers, Anna Perechodjuk, and Thomas Werner. “Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes.” ACS Sustainable Chemistry and Engineering 8, no. 3 (2020): 1651–58. https://doi.org/10.1021/acssuschemeng.9b06662.' ieee: 'C. Wulf, M. Reckers, A. Perechodjuk, and T. Werner, “Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes,” ACS Sustainable Chemistry and Engineering, vol. 8, no. 3, pp. 1651–1658, 2020, doi: 10.1021/acssuschemeng.9b06662.' mla: Wulf, Christoph, et al. “Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes.” ACS Sustainable Chemistry and Engineering, vol. 8, no. 3, American Chemical Society (ACS), 2020, pp. 1651–58, doi:10.1021/acssuschemeng.9b06662. short: C. Wulf, M. Reckers, A. Perechodjuk, T. Werner, ACS Sustainable Chemistry and Engineering 8 (2020) 1651–1658. date_created: 2023-01-22T20:39:32Z date_updated: 2025-11-10T08:51:03Z department: - _id: '35' - _id: '2' - _id: '657' doi: 10.1021/acssuschemeng.9b06662 extern: '1' intvolume: ' 8' issue: '3' keyword: - T1 - T3 - CSSD language: - iso: eng page: 1651-1658 publication: ACS Sustainable Chemistry and Engineering publication_identifier: issn: - 2168-0485 - 2168-0485 publication_status: published publisher: American Chemical Society (ACS) status: public title: Catalytic Systems for the Synthesis of Biscarbonates and Their Impact on the Sequential Preparation of Non-Isocyanate Polyurethanes type: journal_article user_id: '89271' volume: 8 year: '2020' ...