[{"_id":"50740","department":[{"_id":"22"}],"user_id":"92491","keyword":["Cardiology and Cardiovascular Medicine","Nutrition and Dietetics","Endocrinology","Diabetes and Metabolism","Medicine (miscellaneous)"],"language":[{"iso":"eng"}],"publication":"Nutrition, Metabolism and Cardiovascular Diseases","type":"journal_article","status":"public","publisher":"Elsevier BV","date_updated":"2024-01-23T07:20:46Z","date_created":"2024-01-23T07:16:23Z","author":[{"last_name":"Weber","full_name":"Weber, Katharina S.","first_name":"Katharina S."},{"first_name":"Sabrina","last_name":"Schlesinger","full_name":"Schlesinger, Sabrina"},{"first_name":"Alexander","full_name":"Lang, Alexander","last_name":"Lang"},{"first_name":"Klaus","last_name":"Straßburger","full_name":"Straßburger, Klaus"},{"first_name":"Haifa","last_name":"Maalmi","full_name":"Maalmi, Haifa"},{"last_name":"Zhu","full_name":"Zhu, Anna","first_name":"Anna"},{"full_name":"Zaharia, Oana-Patricia","last_name":"Zaharia","first_name":"Oana-Patricia"},{"first_name":"Alexander","last_name":"Strom","full_name":"Strom, Alexander"},{"last_name":"Bönhof","full_name":"Bönhof, Gidon J.","first_name":"Gidon J."},{"full_name":"Goletzke, Janina","last_name":"Goletzke","first_name":"Janina"},{"first_name":"Sandra","full_name":"Trenkamp, Sandra","last_name":"Trenkamp"},{"full_name":"Wagner, Robert","last_name":"Wagner","first_name":"Robert"},{"full_name":"Buyken, Anette","id":"65985","last_name":"Buyken","first_name":"Anette"},{"first_name":"Wolfgang","last_name":"Lieb","full_name":"Lieb, Wolfgang"},{"first_name":"Michael","last_name":"Roden","full_name":"Roden, Michael"},{"last_name":"Herder","full_name":"Herder, Christian","first_name":"Christian"},{"full_name":"Roden, M.","last_name":"Roden","first_name":"M."},{"last_name":"Al-Hasani","full_name":"Al-Hasani, H.","first_name":"H."},{"last_name":"Belgardt","full_name":"Belgardt, B.","first_name":"B."},{"first_name":"E.","last_name":"Lammert","full_name":"Lammert, E."},{"first_name":"G.","full_name":"Bönhof, G.","last_name":"Bönhof"},{"full_name":"Geerling, G.","last_name":"Geerling","first_name":"G."},{"full_name":"Herder, C.","last_name":"Herder","first_name":"C."},{"first_name":"A.","full_name":"Icks, A.","last_name":"Icks"},{"first_name":"K.","last_name":"Jandeleit-Dahm","full_name":"Jandeleit-Dahm, K."},{"full_name":"Kotzka, J.","last_name":"Kotzka","first_name":"J."},{"last_name":"Kuß","full_name":"Kuß, O.","first_name":"O."},{"first_name":"W.","last_name":"Rathmann","full_name":"Rathmann, W."},{"last_name":"Schlesinger","full_name":"Schlesinger, S.","first_name":"S."},{"last_name":"Schrauwen-Hinderling","full_name":"Schrauwen-Hinderling, V.","first_name":"V."},{"first_name":"J.","last_name":"Szendroedi","full_name":"Szendroedi, J."},{"first_name":"S.","last_name":"Trenkamp","full_name":"Trenkamp, S."},{"first_name":"R.","full_name":"Wagner, R.","last_name":"Wagner"}],"title":"Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes","doi":"10.1016/j.numecd.2023.12.026","publication_identifier":{"issn":["0939-4753"]},"publication_status":"published","year":"2024","citation":{"ama":"Weber KS, Schlesinger S, Lang A, et al. Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes. <i>Nutrition, Metabolism and Cardiovascular Diseases</i>. Published online 2024. doi:<a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">10.1016/j.numecd.2023.12.026</a>","ieee":"K. S. Weber <i>et al.</i>, “Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes,” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, 2024, doi: <a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">10.1016/j.numecd.2023.12.026</a>.","chicago":"Weber, Katharina S., Sabrina Schlesinger, Alexander Lang, Klaus Straßburger, Haifa Maalmi, Anna Zhu, Oana-Patricia Zaharia, et al. “Association of Dietary Patterns with Diabetes-Related Comorbidities Varies among Diabetes Endotypes.” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, 2024. <a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">https://doi.org/10.1016/j.numecd.2023.12.026</a>.","bibtex":"@article{Weber_Schlesinger_Lang_Straßburger_Maalmi_Zhu_Zaharia_Strom_Bönhof_Goletzke_et al._2024, title={Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes}, DOI={<a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">10.1016/j.numecd.2023.12.026</a>}, journal={Nutrition, Metabolism and Cardiovascular Diseases}, publisher={Elsevier BV}, author={Weber, Katharina S. and Schlesinger, Sabrina and Lang, Alexander and Straßburger, Klaus and Maalmi, Haifa and Zhu, Anna and Zaharia, Oana-Patricia and Strom, Alexander and Bönhof, Gidon J. and Goletzke, Janina and et al.}, year={2024} }","short":"K.S. Weber, S. Schlesinger, A. Lang, K. Straßburger, H. Maalmi, A. Zhu, O.-P. Zaharia, A. Strom, G.J. Bönhof, J. Goletzke, S. Trenkamp, R. Wagner, A. Buyken, W. Lieb, M. Roden, C. Herder, M. Roden, H. Al-Hasani, B. Belgardt, E. Lammert, G. Bönhof, G. Geerling, C. Herder, A. Icks, K. Jandeleit-Dahm, J. Kotzka, O. Kuß, W. Rathmann, S. Schlesinger, V. Schrauwen-Hinderling, J. Szendroedi, S. Trenkamp, R. Wagner, Nutrition, Metabolism and Cardiovascular Diseases (2024).","mla":"Weber, Katharina S., et al. “Association of Dietary Patterns with Diabetes-Related Comorbidities Varies among Diabetes Endotypes.” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, Elsevier BV, 2024, doi:<a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">10.1016/j.numecd.2023.12.026</a>.","apa":"Weber, K. S., Schlesinger, S., Lang, A., Straßburger, K., Maalmi, H., Zhu, A., Zaharia, O.-P., Strom, A., Bönhof, G. J., Goletzke, J., Trenkamp, S., Wagner, R., Buyken, A., Lieb, W., Roden, M., Herder, C., Roden, M., Al-Hasani, H., Belgardt, B., … Wagner, R. (2024). Association of dietary patterns with diabetes-related comorbidities varies among diabetes endotypes. <i>Nutrition, Metabolism and Cardiovascular Diseases</i>. <a href=\"https://doi.org/10.1016/j.numecd.2023.12.026\">https://doi.org/10.1016/j.numecd.2023.12.026</a>"}},{"publisher":"Elsevier BV","date_created":"2022-08-18T10:34:46Z","title":"Maternal pregnancy weight or gestational weight gain and offspring's blood pressure: A systematic review","issue":"4","year":"2021","keyword":["Cardiology and Cardiovascular Medicine","Nutrition and Dietetics","Endocrinology","Diabetes and Metabolism","Medicine (miscellaneous)"],"language":[{"iso":"eng"}],"publication":"Nutrition, Metabolism and Cardiovascular Diseases","date_updated":"2022-08-18T10:41:47Z","author":[{"first_name":"Helena","full_name":"Ludwig-Walz, Helena","last_name":"Ludwig-Walz"},{"last_name":"Nyasordzi","full_name":"Nyasordzi, Juliana","first_name":"Juliana"},{"first_name":"Katharina S.","last_name":"Weber","full_name":"Weber, Katharina S."},{"id":"65985","full_name":"Buyken, Anette","last_name":"Buyken","first_name":"Anette"},{"first_name":"Anja","last_name":"Kroke","full_name":"Kroke, Anja"}],"volume":32,"doi":"10.1016/j.numecd.2021.11.011","publication_status":"published","publication_identifier":{"issn":["0939-4753"]},"citation":{"apa":"Ludwig-Walz, H., Nyasordzi, J., Weber, K. S., Buyken, A., &#38; Kroke, A. (2021). Maternal pregnancy weight or gestational weight gain and offspring’s blood pressure: A systematic review. <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, <i>32</i>(4), 833–852. <a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">https://doi.org/10.1016/j.numecd.2021.11.011</a>","short":"H. Ludwig-Walz, J. Nyasordzi, K.S. Weber, A. Buyken, A. Kroke, Nutrition, Metabolism and Cardiovascular Diseases 32 (2021) 833–852.","bibtex":"@article{Ludwig-Walz_Nyasordzi_Weber_Buyken_Kroke_2021, title={Maternal pregnancy weight or gestational weight gain and offspring’s blood pressure: A systematic review}, volume={32}, DOI={<a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">10.1016/j.numecd.2021.11.011</a>}, number={4}, journal={Nutrition, Metabolism and Cardiovascular Diseases}, publisher={Elsevier BV}, author={Ludwig-Walz, Helena and Nyasordzi, Juliana and Weber, Katharina S. and Buyken, Anette and Kroke, Anja}, year={2021}, pages={833–852} }","mla":"Ludwig-Walz, Helena, et al. “Maternal Pregnancy Weight or Gestational Weight Gain and Offspring’s Blood Pressure: A Systematic Review.” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, vol. 32, no. 4, Elsevier BV, 2021, pp. 833–52, doi:<a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">10.1016/j.numecd.2021.11.011</a>.","ama":"Ludwig-Walz H, Nyasordzi J, Weber KS, Buyken A, Kroke A. Maternal pregnancy weight or gestational weight gain and offspring’s blood pressure: A systematic review. <i>Nutrition, Metabolism and Cardiovascular Diseases</i>. 2021;32(4):833-852. doi:<a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">10.1016/j.numecd.2021.11.011</a>","chicago":"Ludwig-Walz, Helena, Juliana Nyasordzi, Katharina S. Weber, Anette Buyken, and Anja Kroke. “Maternal Pregnancy Weight or Gestational Weight Gain and Offspring’s Blood Pressure: A Systematic Review.” <i>Nutrition, Metabolism and Cardiovascular Diseases</i> 32, no. 4 (2021): 833–52. <a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">https://doi.org/10.1016/j.numecd.2021.11.011</a>.","ieee":"H. Ludwig-Walz, J. Nyasordzi, K. S. Weber, A. Buyken, and A. Kroke, “Maternal pregnancy weight or gestational weight gain and offspring’s blood pressure: A systematic review,” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, vol. 32, no. 4, pp. 833–852, 2021, doi: <a href=\"https://doi.org/10.1016/j.numecd.2021.11.011\">10.1016/j.numecd.2021.11.011</a>."},"intvolume":"        32","page":"833-852","_id":"33008","user_id":"61597","department":[{"_id":"17"},{"_id":"22"},{"_id":"571"}],"type":"journal_article","status":"public"},{"publication":"Osteoporosis International","type":"journal_article","status":"public","user_id":"89838","_id":"33390","extern":"1","language":[{"iso":"eng"}],"keyword":["Endocrinology","Diabetes and Metabolism"],"issue":"2","publication_identifier":{"issn":["0937-941X","1433-2965"]},"publication_status":"published","page":"431-439","intvolume":"        30","citation":{"mla":"Frings-Meuthen, P., et al. “The Negative Effect of Unloading Exceeds the Bone-Sparing Effect of Alkaline Supplementation: A Bed Rest Study.” <i>Osteoporosis International</i>, vol. 30, no. 2, Springer Science and Business Media LLC, 2018, pp. 431–39, doi:<a href=\"https://doi.org/10.1007/s00198-018-4703-6\">10.1007/s00198-018-4703-6</a>.","bibtex":"@article{Frings-Meuthen_Bernhardt_Bühlmeier_Baecker_May_Heer_2018, title={The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study}, volume={30}, DOI={<a href=\"https://doi.org/10.1007/s00198-018-4703-6\">10.1007/s00198-018-4703-6</a>}, number={2}, journal={Osteoporosis International}, publisher={Springer Science and Business Media LLC}, author={Frings-Meuthen, P. and Bernhardt, G. and Bühlmeier, Judith and Baecker, N. and May, F. and Heer, M.}, year={2018}, pages={431–439} }","short":"P. Frings-Meuthen, G. Bernhardt, J. Bühlmeier, N. Baecker, F. May, M. Heer, Osteoporosis International 30 (2018) 431–439.","apa":"Frings-Meuthen, P., Bernhardt, G., Bühlmeier, J., Baecker, N., May, F., &#38; Heer, M. (2018). The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study. <i>Osteoporosis International</i>, <i>30</i>(2), 431–439. <a href=\"https://doi.org/10.1007/s00198-018-4703-6\">https://doi.org/10.1007/s00198-018-4703-6</a>","ama":"Frings-Meuthen P, Bernhardt G, Bühlmeier J, Baecker N, May F, Heer M. The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study. <i>Osteoporosis International</i>. 2018;30(2):431-439. doi:<a href=\"https://doi.org/10.1007/s00198-018-4703-6\">10.1007/s00198-018-4703-6</a>","chicago":"Frings-Meuthen, P., G. Bernhardt, Judith Bühlmeier, N. Baecker, F. May, and M. Heer. “The Negative Effect of Unloading Exceeds the Bone-Sparing Effect of Alkaline Supplementation: A Bed Rest Study.” <i>Osteoporosis International</i> 30, no. 2 (2018): 431–39. <a href=\"https://doi.org/10.1007/s00198-018-4703-6\">https://doi.org/10.1007/s00198-018-4703-6</a>.","ieee":"P. Frings-Meuthen, G. Bernhardt, J. Bühlmeier, N. Baecker, F. May, and M. Heer, “The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study,” <i>Osteoporosis International</i>, vol. 30, no. 2, pp. 431–439, 2018, doi: <a href=\"https://doi.org/10.1007/s00198-018-4703-6\">10.1007/s00198-018-4703-6</a>."},"year":"2018","volume":30,"date_created":"2022-09-15T09:32:11Z","author":[{"last_name":"Frings-Meuthen","full_name":"Frings-Meuthen, P.","first_name":"P."},{"last_name":"Bernhardt","full_name":"Bernhardt, G.","first_name":"G."},{"last_name":"Bühlmeier","id":"89838","full_name":"Bühlmeier, Judith","first_name":"Judith"},{"first_name":"N.","last_name":"Baecker","full_name":"Baecker, N."},{"full_name":"May, F.","last_name":"May","first_name":"F."},{"full_name":"Heer, M.","last_name":"Heer","first_name":"M."}],"publisher":"Springer Science and Business Media LLC","date_updated":"2022-09-15T09:44:04Z","doi":"10.1007/s00198-018-4703-6","title":"The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study"},{"publication_identifier":{"issn":["0021-972X","1945-7197"]},"publication_status":"published","issue":"5","year":"2018","intvolume":"       103","page":"1910-1920","citation":{"ama":"Rudwill F, O’Gorman D, Lefai E, et al. Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable. <i>The Journal of Clinical Endocrinology &#38;amp; Metabolism</i>. 2018;103(5):1910-1920. doi:<a href=\"https://doi.org/10.1210/jc.2017-02267\">10.1210/jc.2017-02267</a>","chicago":"Rudwill, Floriane, Donal O’Gorman, Etienne Lefai, Isabelle Chery, Alexandre Zahariev, Sylvie Normand, Allan F Pagano, et al. “Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable.” <i>The Journal of Clinical Endocrinology &#38;amp; Metabolism</i> 103, no. 5 (2018): 1910–20. <a href=\"https://doi.org/10.1210/jc.2017-02267\">https://doi.org/10.1210/jc.2017-02267</a>.","ieee":"F. Rudwill <i>et al.</i>, “Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable,” <i>The Journal of Clinical Endocrinology &#38;amp; Metabolism</i>, vol. 103, no. 5, pp. 1910–1920, 2018, doi: <a href=\"https://doi.org/10.1210/jc.2017-02267\">10.1210/jc.2017-02267</a>.","mla":"Rudwill, Floriane, et al. “Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable.” <i>The Journal of Clinical Endocrinology &#38;amp; Metabolism</i>, vol. 103, no. 5, The Endocrine Society, 2018, pp. 1910–20, doi:<a href=\"https://doi.org/10.1210/jc.2017-02267\">10.1210/jc.2017-02267</a>.","bibtex":"@article{Rudwill_O’Gorman_Lefai_Chery_Zahariev_Normand_Pagano_Chopard_Damiot_Laurens_et al._2018, title={Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable}, volume={103}, DOI={<a href=\"https://doi.org/10.1210/jc.2017-02267\">10.1210/jc.2017-02267</a>}, number={5}, journal={The Journal of Clinical Endocrinology &#38;amp; Metabolism}, publisher={The Endocrine Society}, author={Rudwill, Floriane and O’Gorman, Donal and Lefai, Etienne and Chery, Isabelle and Zahariev, Alexandre and Normand, Sylvie and Pagano, Allan F and Chopard, Angèle and Damiot, Anthony and Laurens, Claire and et al.}, year={2018}, pages={1910–1920} }","short":"F. Rudwill, D. O’Gorman, E. Lefai, I. Chery, A. Zahariev, S. Normand, A.F. Pagano, A. Chopard, A. Damiot, C. Laurens, L. Hodson, E. Canet-Soulas, M. Heer, P.F. Meuthen, J. Bühlmeier, N. Baecker, L. Meiller, G. Gauquelin-Koch, S. Blanc, C. Simon, A. Bergouignan, The Journal of Clinical Endocrinology &#38;amp; Metabolism 103 (2018) 1910–1920.","apa":"Rudwill, F., O’Gorman, D., Lefai, E., Chery, I., Zahariev, A., Normand, S., Pagano, A. F., Chopard, A., Damiot, A., Laurens, C., Hodson, L., Canet-Soulas, E., Heer, M., Meuthen, P. F., Bühlmeier, J., Baecker, N., Meiller, L., Gauquelin-Koch, G., Blanc, S., … Bergouignan, A. (2018). Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable. <i>The Journal of Clinical Endocrinology &#38;amp; Metabolism</i>, <i>103</i>(5), 1910–1920. <a href=\"https://doi.org/10.1210/jc.2017-02267\">https://doi.org/10.1210/jc.2017-02267</a>"},"publisher":"The Endocrine Society","date_updated":"2022-09-15T09:44:47Z","volume":103,"date_created":"2022-09-15T09:33:08Z","author":[{"first_name":"Floriane","last_name":"Rudwill","full_name":"Rudwill, Floriane"},{"full_name":"O’Gorman, Donal","last_name":"O’Gorman","first_name":"Donal"},{"first_name":"Etienne","full_name":"Lefai, Etienne","last_name":"Lefai"},{"first_name":"Isabelle","last_name":"Chery","full_name":"Chery, Isabelle"},{"first_name":"Alexandre","full_name":"Zahariev, Alexandre","last_name":"Zahariev"},{"first_name":"Sylvie","full_name":"Normand, Sylvie","last_name":"Normand"},{"full_name":"Pagano, Allan F","last_name":"Pagano","first_name":"Allan F"},{"last_name":"Chopard","full_name":"Chopard, Angèle","first_name":"Angèle"},{"first_name":"Anthony","last_name":"Damiot","full_name":"Damiot, Anthony"},{"first_name":"Claire","full_name":"Laurens, Claire","last_name":"Laurens"},{"first_name":"Leanne","last_name":"Hodson","full_name":"Hodson, Leanne"},{"last_name":"Canet-Soulas","full_name":"Canet-Soulas, Emmanuelle","first_name":"Emmanuelle"},{"first_name":"Martina","last_name":"Heer","full_name":"Heer, Martina"},{"first_name":"Petra Frings","last_name":"Meuthen","full_name":"Meuthen, Petra Frings"},{"full_name":"Bühlmeier, Judith","id":"89838","last_name":"Bühlmeier","first_name":"Judith"},{"first_name":"Natalie","full_name":"Baecker, Natalie","last_name":"Baecker"},{"full_name":"Meiller, Laure","last_name":"Meiller","first_name":"Laure"},{"first_name":"Guillemette","full_name":"Gauquelin-Koch, Guillemette","last_name":"Gauquelin-Koch"},{"last_name":"Blanc","full_name":"Blanc, Stéphane","first_name":"Stéphane"},{"full_name":"Simon, Chantal","last_name":"Simon","first_name":"Chantal"},{"last_name":"Bergouignan","full_name":"Bergouignan, Audrey","first_name":"Audrey"}],"title":"Metabolic Inflexibility Is an Early Marker of Bed-Rest–Induced Glucose Intolerance Even When Fat Mass Is Stable","doi":"10.1210/jc.2017-02267","publication":"The Journal of Clinical Endocrinology &amp; Metabolism","type":"journal_article","abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title>\r\n               <jats:sec>\r\n                  <jats:title>Context</jats:title>\r\n                  <jats:p>The effects of energy-balanced bed rest on metabolic flexibility have not been thoroughly examined.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Objective</jats:title>\r\n                  <jats:p>We investigated the effects of 21 days of bed rest, with and without whey protein supplementation, on metabolic flexibility while maintaining energy balance. We hypothesized that protein supplementation mitigates metabolic inflexibility by preventing muscle atrophy.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Design and Setting</jats:title>\r\n                  <jats:p>Randomized crossover longitudinal study conducted at the German Aerospace Center, Cologne, Germany.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Participants and Interventions</jats:title>\r\n                  <jats:p>Ten healthy men were randomly assigned to dietary countermeasure or isocaloric control diet during a 21-day bed rest.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Outcome Measures</jats:title>\r\n                  <jats:p>Before and at the end of the bed rest, metabolic flexibility was assessed during a meal test. Secondary outcomes were glucose tolerance by oral glucose tolerance test, body composition by dual energy X-ray absorptiometry, ectopic fat storage by magnetic resonance imaging, and inflammation and oxidative stress markers.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Results</jats:title>\r\n                  <jats:p>Bed rest decreased the ability to switch from fat to carbohydrate oxidation when transitioning from fasted to fed states (i.e., metabolic inflexibility), antioxidant capacity, fat-free mass (FFM), and muscle insulin sensitivity along with greater fat deposition in muscle (P &amp;lt; 0.05 for all). Changes in fasting insulin and inflammation were not observed. However, glucose tolerance was reduced during acute overfeeding. Protein supplementation did not prevent FFM loss and metabolic alterations.</jats:p>\r\n               </jats:sec>\r\n               <jats:sec>\r\n                  <jats:title>Conclusions</jats:title>\r\n                  <jats:p>Physical inactivity triggers metabolic inflexibility, even when energy balance is maintained. Although reduced insulin sensitivity and increased fat deposition were observed at the muscle level, systemic glucose intolerance was detected only in response to a moderately high-fat meal. This finding supports the role of physical inactivity in metabolic inflexibility and suggests that metabolic inflexibility precedes systemic glucose intolerance.</jats:p>\r\n               </jats:sec>"}],"status":"public","_id":"33392","user_id":"89838","keyword":["Biochemistry (medical)","Clinical Biochemistry","Endocrinology","Biochemistry","Endocrinology","Diabetes and Metabolism"],"extern":"1","language":[{"iso":"eng"}]},{"_id":"43015","department":[{"_id":"17"},{"_id":"22"},{"_id":"571"}],"user_id":"61597","keyword":["Cardiology and Cardiovascular Medicine","Nutrition and Dietetics","Endocrinology","Diabetes and Metabolism","Medicine (miscellaneous)"],"language":[{"iso":"eng"}],"publication":"Nutrition, Metabolism and Cardiovascular Diseases","type":"journal_article","status":"public","date_updated":"2023-03-14T10:40:55Z","publisher":"Elsevier BV","volume":28,"date_created":"2023-03-14T10:38:41Z","author":[{"first_name":"Bianca","full_name":"Stutz, Bianca","id":"77099","last_name":"Stutz"},{"full_name":"Ahola, A.J.","last_name":"Ahola","first_name":"A.J."},{"last_name":"Harjutsalo","full_name":"Harjutsalo, V.","first_name":"V."},{"first_name":"C.","last_name":"Forsblom","full_name":"Forsblom, C."},{"full_name":"Groop, P.-H.","last_name":"Groop","first_name":"P.-H."}],"title":"Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes","doi":"10.1016/j.numecd.2018.01.011","publication_identifier":{"issn":["0939-4753"]},"publication_status":"published","issue":"5","year":"2018","page":"470-476","intvolume":"        28","citation":{"ama":"Stutz B, Ahola AJ, Harjutsalo V, Forsblom C, Groop P-H. Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes. <i>Nutrition, Metabolism and Cardiovascular Diseases</i>. 2018;28(5):470-476. doi:<a href=\"https://doi.org/10.1016/j.numecd.2018.01.011\">10.1016/j.numecd.2018.01.011</a>","ieee":"B. Stutz, A. J. Ahola, V. Harjutsalo, C. Forsblom, and P.-H. Groop, “Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes,” <i>Nutrition, Metabolism and Cardiovascular Diseases</i>, vol. 28, no. 5, pp. 470–476, 2018, doi: <a href=\"https://doi.org/10.1016/j.numecd.2018.01.011\">10.1016/j.numecd.2018.01.011</a>.","chicago":"Stutz, Bianca, A.J. Ahola, V. Harjutsalo, C. Forsblom, and P.-H. 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