---
_id: '45824'
abstract:
- lang: eng
  text: <jats:p>As cognitive function is critical for muscle coordination, cognitive
    training may also improve neuromuscular control strategy and knee function following
    an anterior cruciate ligament reconstruction (ACLR). The purpose of this case-control
    study was to examine the effects of cognitive training on joint stiffness regulation
    in response to negative visual stimuli and knee function following ACLR. A total
    of 20 ACLR patients and 20 healthy controls received four weeks of online cognitive
    training. Executive function, joint stiffness in response to emotionally evocative
    visual stimuli (neutral, fearful, knee injury related), and knee function outcomes
    before and after the intervention were compared. Both groups improved executive
    function following the intervention (p = 0.005). The ACLR group had greater mid-range
    stiffness in response to fearful (p = 0.024) and injury-related pictures (p =
    0.017) than neutral contents before the intervention, while no post-intervention
    stiffness differences were observed among picture types. The ACLR group showed
    better single-legged hop for distance after cognitive training (p = 0.047), while
    the healthy group demonstrated no improvement. Cognitive training enhanced executive
    function, which may reduce joint stiffness dysregulation in response to emotionally
    arousing images and improve knee function in ACLR patients, presumably by facilitating
    neural processing necessary for neuromuscular control.</jats:p>
article_number: '1875'
author:
- first_name: Yong Woo
  full_name: An, Yong Woo
  last_name: An
- first_name: Kyung-Min
  full_name: Kim, Kyung-Min
  last_name: Kim
- first_name: Andrea
  full_name: DiTrani Lobacz, Andrea
  last_name: DiTrani Lobacz
- first_name: Jochen
  full_name: Baumeister, Jochen
  id: '46'
  last_name: Baumeister
  orcid: 0000-0003-2683-5826
- first_name: Jill S.
  full_name: Higginson, Jill S.
  last_name: Higginson
- first_name: Jeffrey
  full_name: Rosen, Jeffrey
  last_name: Rosen
- first_name: Charles Buz
  full_name: Swanik, Charles Buz
  last_name: Swanik
citation:
  ama: An YW, Kim K-M, DiTrani Lobacz A, et al. Cognitive Training Improves Joint
    Stiffness Regulation and Function in ACLR Patients Compared to Healthy Controls.
    <i>Healthcare</i>. 2023;11(13). doi:<a href="https://doi.org/10.3390/healthcare11131875">10.3390/healthcare11131875</a>
  apa: An, Y. W., Kim, K.-M., DiTrani Lobacz, A., Baumeister, J., Higginson, J. S.,
    Rosen, J., &#38; Swanik, C. B. (2023). Cognitive Training Improves Joint Stiffness
    Regulation and Function in ACLR Patients Compared to Healthy Controls. <i>Healthcare</i>,
    <i>11</i>(13), Article 1875. <a href="https://doi.org/10.3390/healthcare11131875">https://doi.org/10.3390/healthcare11131875</a>
  bibtex: '@article{An_Kim_DiTrani Lobacz_Baumeister_Higginson_Rosen_Swanik_2023,
    title={Cognitive Training Improves Joint Stiffness Regulation and Function in
    ACLR Patients Compared to Healthy Controls}, volume={11}, DOI={<a href="https://doi.org/10.3390/healthcare11131875">10.3390/healthcare11131875</a>},
    number={131875}, journal={Healthcare}, publisher={MDPI AG}, author={An, Yong Woo
    and Kim, Kyung-Min and DiTrani Lobacz, Andrea and Baumeister, Jochen and Higginson,
    Jill S. and Rosen, Jeffrey and Swanik, Charles Buz}, year={2023} }'
  chicago: An, Yong Woo, Kyung-Min Kim, Andrea DiTrani Lobacz, Jochen Baumeister,
    Jill S. Higginson, Jeffrey Rosen, and Charles Buz Swanik. “Cognitive Training
    Improves Joint Stiffness Regulation and Function in ACLR Patients Compared to
    Healthy Controls.” <i>Healthcare</i> 11, no. 13 (2023). <a href="https://doi.org/10.3390/healthcare11131875">https://doi.org/10.3390/healthcare11131875</a>.
  ieee: 'Y. W. An <i>et al.</i>, “Cognitive Training Improves Joint Stiffness Regulation
    and Function in ACLR Patients Compared to Healthy Controls,” <i>Healthcare</i>,
    vol. 11, no. 13, Art. no. 1875, 2023, doi: <a href="https://doi.org/10.3390/healthcare11131875">10.3390/healthcare11131875</a>.'
  mla: An, Yong Woo, et al. “Cognitive Training Improves Joint Stiffness Regulation
    and Function in ACLR Patients Compared to Healthy Controls.” <i>Healthcare</i>,
    vol. 11, no. 13, 1875, MDPI AG, 2023, doi:<a href="https://doi.org/10.3390/healthcare11131875">10.3390/healthcare11131875</a>.
  short: Y.W. An, K.-M. Kim, A. DiTrani Lobacz, J. Baumeister, J.S. Higginson, J.
    Rosen, C.B. Swanik, Healthcare 11 (2023).
date_created: 2023-06-30T13:47:33Z
date_updated: 2025-03-11T10:31:53Z
department:
- _id: '172'
doi: 10.3390/healthcare11131875
intvolume: '        11'
issue: '13'
keyword:
- Health Information Management
- Health Informatics
- Health Policy
- Leadership and Management
language:
- iso: eng
publication: Healthcare
publication_identifier:
  issn:
  - 2227-9032
publication_status: published
publisher: MDPI AG
status: public
title: Cognitive Training Improves Joint Stiffness Regulation and Function in ACLR
  Patients Compared to Healthy Controls
type: journal_article
user_id: '46'
volume: 11
year: '2023'
...
---
_id: '30906'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title><jats:sec>\r\n                <jats:title>Background</jats:title>\r\n
    \               <jats:p>Hand amputation can have a truly debilitating impact on
    the life of the affected person. A multifunctional myoelectric prosthesis controlled
    using pattern classification can be used to restore some of the lost motor abilities.
    However, learning to control an advanced prosthesis can be a challenging task,
    but virtual and augmented reality (AR) provide means to create an engaging and
    motivating training.</jats:p>\r\n              </jats:sec><jats:sec>\r\n                <jats:title>Methods</jats:title>\r\n
    \               <jats:p>In this study, we present a novel training framework that
    integrates virtual elements within a real scene (AR) while allowing the view from
    the first-person perspective. The framework was evaluated in 13 able-bodied subjects
    and a limb-deficient person divided into intervention (IG) and control (CG) groups.
    The IG received training by performing simulated clothespin task and both groups
    conducted a pre- and posttest with a real prosthesis. When training with the AR,
    the subjects received visual feedback on the generated grasping force. The main
    outcome measure was the number of pins that were successfully transferred within
    20 min (task duration), while the number of dropped and broken pins were also
    registered. The participants were asked to score the difficulty of the real task
    (posttest), fun-factor and motivation, as well as the utility of the feedback.</jats:p>\r\n
    \             </jats:sec><jats:sec>\r\n                <jats:title>Results</jats:title>\r\n
    \               <jats:p>The performance (median/interquartile range) consistently
    increased during the training sessions (4/3 to 22/4). While the results were similar
    for the two groups in the pretest, the performance improved in the posttest only
    in IG. In addition, the subjects in IG transferred significantly more pins (28/10.5
    versus 14.5/11), and dropped (1/2.5 versus 3.5/2) and broke (5/3.8 versus 14.5/9)
    significantly fewer pins in the posttest compared to CG. The participants in IG
    assigned (mean ± std) significantly lower scores to the difficulty compared to
    CG (5.2 ± 1.9 versus 7.1 ± 0.9), and they highly rated the fun factor (8.7 ± 1.3)
    and usefulness of feedback (8.5 ± 1.7).</jats:p>\r\n              </jats:sec><jats:sec>\r\n
    \               <jats:title>Conclusion</jats:title>\r\n                <jats:p>The
    results demonstrated that the proposed AR system allows for the transfer of skills
    from the simulated to the real task while providing a positive user experience.
    The present study demonstrates the effectiveness and flexibility of the proposed
    AR framework. Importantly, the developed system is open source and available for
    download and further development.</jats:p>\r\n              </jats:sec>"
article_number: '25'
author:
- first_name: Alexander
  full_name: Boschmann, Alexander
  last_name: Boschmann
- first_name: Dorothee
  full_name: Neuhaus, Dorothee
  last_name: Neuhaus
- first_name: Sarah
  full_name: Vogt, Sarah
  last_name: Vogt
- first_name: Christian
  full_name: Kaltschmidt, Christian
  last_name: Kaltschmidt
- first_name: Marco
  full_name: Platzner, Marco
  id: '398'
  last_name: Platzner
- first_name: Strahinja
  full_name: Dosen, Strahinja
  last_name: Dosen
citation:
  ama: Boschmann A, Neuhaus D, Vogt S, Kaltschmidt C, Platzner M, Dosen S. Immersive
    augmented reality system for the training of pattern classification control with
    a myoelectric prosthesis. <i>Journal of NeuroEngineering and Rehabilitation</i>.
    2021;18(1). doi:<a href="https://doi.org/10.1186/s12984-021-00822-6">10.1186/s12984-021-00822-6</a>
  apa: Boschmann, A., Neuhaus, D., Vogt, S., Kaltschmidt, C., Platzner, M., &#38;
    Dosen, S. (2021). Immersive augmented reality system for the training of pattern
    classification control with a myoelectric prosthesis. <i>Journal of NeuroEngineering
    and Rehabilitation</i>, <i>18</i>(1), Article 25. <a href="https://doi.org/10.1186/s12984-021-00822-6">https://doi.org/10.1186/s12984-021-00822-6</a>
  bibtex: '@article{Boschmann_Neuhaus_Vogt_Kaltschmidt_Platzner_Dosen_2021, title={Immersive
    augmented reality system for the training of pattern classification control with
    a myoelectric prosthesis}, volume={18}, DOI={<a href="https://doi.org/10.1186/s12984-021-00822-6">10.1186/s12984-021-00822-6</a>},
    number={125}, journal={Journal of NeuroEngineering and Rehabilitation}, publisher={Springer
    Science and Business Media LLC}, author={Boschmann, Alexander and Neuhaus, Dorothee
    and Vogt, Sarah and Kaltschmidt, Christian and Platzner, Marco and Dosen, Strahinja},
    year={2021} }'
  chicago: Boschmann, Alexander, Dorothee Neuhaus, Sarah Vogt, Christian Kaltschmidt,
    Marco Platzner, and Strahinja Dosen. “Immersive Augmented Reality System for the
    Training of Pattern Classification Control with a Myoelectric Prosthesis.” <i>Journal
    of NeuroEngineering and Rehabilitation</i> 18, no. 1 (2021). <a href="https://doi.org/10.1186/s12984-021-00822-6">https://doi.org/10.1186/s12984-021-00822-6</a>.
  ieee: 'A. Boschmann, D. Neuhaus, S. Vogt, C. Kaltschmidt, M. Platzner, and S. Dosen,
    “Immersive augmented reality system for the training of pattern classification
    control with a myoelectric prosthesis,” <i>Journal of NeuroEngineering and Rehabilitation</i>,
    vol. 18, no. 1, Art. no. 25, 2021, doi: <a href="https://doi.org/10.1186/s12984-021-00822-6">10.1186/s12984-021-00822-6</a>.'
  mla: Boschmann, Alexander, et al. “Immersive Augmented Reality System for the Training
    of Pattern Classification Control with a Myoelectric Prosthesis.” <i>Journal of
    NeuroEngineering and Rehabilitation</i>, vol. 18, no. 1, 25, Springer Science
    and Business Media LLC, 2021, doi:<a href="https://doi.org/10.1186/s12984-021-00822-6">10.1186/s12984-021-00822-6</a>.
  short: A. Boschmann, D. Neuhaus, S. Vogt, C. Kaltschmidt, M. Platzner, S. Dosen,
    Journal of NeuroEngineering and Rehabilitation 18 (2021).
date_created: 2022-04-18T10:02:20Z
date_updated: 2022-04-18T10:04:16Z
department:
- _id: '78'
doi: 10.1186/s12984-021-00822-6
intvolume: '        18'
issue: '1'
keyword:
- Health Informatics
- Rehabilitation
language:
- iso: eng
publication: Journal of NeuroEngineering and Rehabilitation
publication_identifier:
  issn:
  - 1743-0003
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Immersive augmented reality system for the training of pattern classification
  control with a myoelectric prosthesis
type: journal_article
user_id: '398'
volume: 18
year: '2021'
...
---
_id: '37154'
abstract:
- lang: eng
  text: '<jats:p> The application of artificial intelligence (AI) not only yields
    in advantages for healthcare but raises several ethical questions. Extant research
    on ethical considerations of AI in digital health is quite sparse and a holistic
    overview is lacking. A systematic literature review searching across 853 peer-reviewed
    journals and conferences yielded in 50 relevant articles categorized in five major
    ethical principles: beneficence, non-maleficence, autonomy, justice, and explicability.
    The ethical landscape of AI in digital health is portrayed including a snapshot
    guiding future development. The status quo highlights potential areas with little
    empirical but required research. Less explored areas with remaining ethical questions
    are validated and guide scholars’ efforts by outlining an overview of addressed
    ethical principles and intensity of studies including correlations. Practitioners
    understand novel questions AI raises eventually leading to properly regulated
    implementations and further comprehend that society is on its way from supporting
    technologies to autonomous decision-making systems. </jats:p>'
article_number: '146045822110523'
author:
- first_name: Nicholas RJ
  full_name: Möllmann, Nicholas RJ
  last_name: Möllmann
- first_name: Milad
  full_name: Mirbabaie, Milad
  id: '88691'
  last_name: Mirbabaie
- first_name: Stefan
  full_name: Stieglitz, Stefan
  last_name: Stieglitz
citation:
  ama: Möllmann NR, Mirbabaie M, Stieglitz S. Is it alright to use artificial intelligence
    in digital health? A systematic literature review on ethical considerations. <i>Health
    Informatics Journal</i>. 2021;27(4). doi:<a href="https://doi.org/10.1177/14604582211052391">10.1177/14604582211052391</a>
  apa: Möllmann, N. R., Mirbabaie, M., &#38; Stieglitz, S. (2021). Is it alright to
    use artificial intelligence in digital health? A systematic literature review
    on ethical considerations. <i>Health Informatics Journal</i>, <i>27</i>(4), Article
    146045822110523. <a href="https://doi.org/10.1177/14604582211052391">https://doi.org/10.1177/14604582211052391</a>
  bibtex: '@article{Möllmann_Mirbabaie_Stieglitz_2021, title={Is it alright to use
    artificial intelligence in digital health? A systematic literature review on ethical
    considerations}, volume={27}, DOI={<a href="https://doi.org/10.1177/14604582211052391">10.1177/14604582211052391</a>},
    number={4146045822110523}, journal={Health Informatics Journal}, publisher={SAGE
    Publications}, author={Möllmann, Nicholas RJ and Mirbabaie, Milad and Stieglitz,
    Stefan}, year={2021} }'
  chicago: Möllmann, Nicholas RJ, Milad Mirbabaie, and Stefan Stieglitz. “Is It Alright
    to Use Artificial Intelligence in Digital Health? A Systematic Literature Review
    on Ethical Considerations.” <i>Health Informatics Journal</i> 27, no. 4 (2021).
    <a href="https://doi.org/10.1177/14604582211052391">https://doi.org/10.1177/14604582211052391</a>.
  ieee: 'N. R. Möllmann, M. Mirbabaie, and S. Stieglitz, “Is it alright to use artificial
    intelligence in digital health? A systematic literature review on ethical considerations,”
    <i>Health Informatics Journal</i>, vol. 27, no. 4, Art. no. 146045822110523, 2021,
    doi: <a href="https://doi.org/10.1177/14604582211052391">10.1177/14604582211052391</a>.'
  mla: Möllmann, Nicholas RJ, et al. “Is It Alright to Use Artificial Intelligence
    in Digital Health? A Systematic Literature Review on Ethical Considerations.”
    <i>Health Informatics Journal</i>, vol. 27, no. 4, 146045822110523, SAGE Publications,
    2021, doi:<a href="https://doi.org/10.1177/14604582211052391">10.1177/14604582211052391</a>.
  short: N.R. Möllmann, M. Mirbabaie, S. Stieglitz, Health Informatics Journal 27
    (2021).
date_created: 2023-01-17T15:34:53Z
date_updated: 2023-01-18T07:58:55Z
doi: 10.1177/14604582211052391
intvolume: '        27'
issue: '4'
keyword:
- Health Informatics
language:
- iso: eng
publication: Health Informatics Journal
publication_identifier:
  issn:
  - 1460-4582
  - 1741-2811
publication_status: published
publisher: SAGE Publications
status: public
title: Is it alright to use artificial intelligence in digital health? A systematic
  literature review on ethical considerations
type: journal_article
user_id: '80546'
volume: 27
year: '2021'
...
