---
_id: '32416'
abstract:
- lang: eng
  text: In recent years, sequence-defined oligomers (SDOs) gained increasing interest
    due to their perfectly controlled molecular structure, thus providing defined
    properties. In order to tune the properties, different functionalities need to
    be incorporated into the oligomers and the chain tacticity needs to be controlled.
    Beside the synthesis of SDOs, suitable methods need to be found to analyze the
    molecular structure. In this work, oligomers exhibiting an alternating or block-wise
    sequence of side chain functionalities were analyzed using a hyphenation of ultra-high-performance
    liquid chromatography and electrospray ionization mass spectrometry enhanced by
    ion mobility separation (IMS). Moieties in the side chains were varied according
    to polarity and bulkiness. Moreover, chain tacticity was varied. Drift times in
    the IMS cell and the corresponding collision cross section (CCS) values were shown
    to be individual parameters allowing the identification of SDOs, even in the case
    that SDO structures only differ in sequence or tacticity of side chain functionalities.
    Thus, a library of CCS values was obtained as reference used for the analysis
    of complex mixtures of SDOs.
article_type: original
author:
- first_name: Marie-Theres
  full_name: Berg, Marie-Theres
  last_name: Berg
- first_name: Artjom
  full_name: Herberg, Artjom
  id: '94'
  last_name: Herberg
- first_name: Dirk
  full_name: Kuckling, Dirk
  id: '287'
  last_name: Kuckling
citation:
  ama: Berg M-T, Herberg A, Kuckling D. Hyphenation of ultra-high-performance liquid
    chromatography and ion mobility mass spectrometry for the analysis of sequence-defined
    oligomers with different functionalities and tacticity. <i>International Journal
    of Polymer Analysis and Characterization</i>. Published online 2022:1-12. doi:<a
    href="https://doi.org/10.1080/1023666x.2022.2100968">10.1080/1023666x.2022.2100968</a>
  apa: Berg, M.-T., Herberg, A., &#38; Kuckling, D. (2022). Hyphenation of ultra-high-performance
    liquid chromatography and ion mobility mass spectrometry for the analysis of sequence-defined
    oligomers with different functionalities and tacticity. <i>International Journal
    of Polymer Analysis and Characterization</i>, 1–12. <a href="https://doi.org/10.1080/1023666x.2022.2100968">https://doi.org/10.1080/1023666x.2022.2100968</a>
  bibtex: '@article{Berg_Herberg_Kuckling_2022, title={Hyphenation of ultra-high-performance
    liquid chromatography and ion mobility mass spectrometry for the analysis of sequence-defined
    oligomers with different functionalities and tacticity}, DOI={<a href="https://doi.org/10.1080/1023666x.2022.2100968">10.1080/1023666x.2022.2100968</a>},
    journal={International Journal of Polymer Analysis and Characterization}, publisher={Informa
    UK Limited}, author={Berg, Marie-Theres and Herberg, Artjom and Kuckling, Dirk},
    year={2022}, pages={1–12} }'
  chicago: Berg, Marie-Theres, Artjom Herberg, and Dirk Kuckling. “Hyphenation of
    Ultra-High-Performance Liquid Chromatography and Ion Mobility Mass Spectrometry
    for the Analysis of Sequence-Defined Oligomers with Different Functionalities
    and Tacticity.” <i>International Journal of Polymer Analysis and Characterization</i>,
    2022, 1–12. <a href="https://doi.org/10.1080/1023666x.2022.2100968">https://doi.org/10.1080/1023666x.2022.2100968</a>.
  ieee: 'M.-T. Berg, A. Herberg, and D. Kuckling, “Hyphenation of ultra-high-performance
    liquid chromatography and ion mobility mass spectrometry for the analysis of sequence-defined
    oligomers with different functionalities and tacticity,” <i>International Journal
    of Polymer Analysis and Characterization</i>, pp. 1–12, 2022, doi: <a href="https://doi.org/10.1080/1023666x.2022.2100968">10.1080/1023666x.2022.2100968</a>.'
  mla: Berg, Marie-Theres, et al. “Hyphenation of Ultra-High-Performance Liquid Chromatography
    and Ion Mobility Mass Spectrometry for the Analysis of Sequence-Defined Oligomers
    with Different Functionalities and Tacticity.” <i>International Journal of Polymer
    Analysis and Characterization</i>, Informa UK Limited, 2022, pp. 1–12, doi:<a
    href="https://doi.org/10.1080/1023666x.2022.2100968">10.1080/1023666x.2022.2100968</a>.
  short: M.-T. Berg, A. Herberg, D. Kuckling, International Journal of Polymer Analysis
    and Characterization (2022) 1–12.
date_created: 2022-07-26T06:38:52Z
date_updated: 2023-01-10T08:14:52Z
department:
- _id: '163'
doi: 10.1080/1023666x.2022.2100968
keyword:
- Ultra-high-performance liquid chromatography
- ion mobility separation
- mass spectrometry
- LC-MS hyphenation
- sequence-defined oligomers
language:
- iso: eng
page: 1-12
publication: International Journal of Polymer Analysis and Characterization
publication_identifier:
  issn:
  - 1023-666X
  - 1563-5341
publication_status: published
publisher: Informa UK Limited
status: public
title: Hyphenation of ultra-high-performance liquid chromatography and ion mobility
  mass spectrometry for the analysis of sequence-defined oligomers with different
  functionalities and tacticity
type: journal_article
user_id: '94'
year: '2022'
...
---
_id: '44375'
author:
- first_name: Dotse Selali
  full_name: Chormey, Dotse Selali
  last_name: Chormey
- first_name: Güldeniz
  full_name: Tonbul, Güldeniz
  id: '89054'
  last_name: Tonbul
  orcid: 0000-0002-0999-9995
- first_name: Güneş
  full_name: Soylu, Güneş
  last_name: Soylu
- first_name: Ahmet
  full_name: Saygılar, Ahmet
  last_name: Saygılar
- first_name: Sezgin
  full_name: Bakırdere, Sezgin
  last_name: Bakırdere
citation:
  ama: Chormey DS, Tonbul G, Soylu G, Saygılar A, Bakırdere S. Determination of Four
    Priority Polycyclic Aromatic Hydrocarbons in Food Samples by Gas Chromatography
    – Mass Spectrometry (GC-MS) after Vortex Assisted Dispersive Liquid-Liquid Microextraction
    (DLLME). <i>Analytical Letters</i>. 2021;55(2):237-245. doi:<a href="https://doi.org/10.1080/00032719.2021.1922432">10.1080/00032719.2021.1922432</a>
  apa: Chormey, D. S., Tonbul, G., Soylu, G., Saygılar, A., &#38; Bakırdere, S. (2021).
    Determination of Four Priority Polycyclic Aromatic Hydrocarbons in Food Samples
    by Gas Chromatography – Mass Spectrometry (GC-MS) after Vortex Assisted Dispersive
    Liquid-Liquid Microextraction (DLLME). <i>Analytical Letters</i>, <i>55</i>(2),
    237–245. <a href="https://doi.org/10.1080/00032719.2021.1922432">https://doi.org/10.1080/00032719.2021.1922432</a>
  bibtex: '@article{Chormey_Tonbul_Soylu_Saygılar_Bakırdere_2021, title={Determination
    of Four Priority Polycyclic Aromatic Hydrocarbons in Food Samples by Gas Chromatography
    – Mass Spectrometry (GC-MS) after Vortex Assisted Dispersive Liquid-Liquid Microextraction
    (DLLME)}, volume={55}, DOI={<a href="https://doi.org/10.1080/00032719.2021.1922432">10.1080/00032719.2021.1922432</a>},
    number={2}, journal={Analytical Letters}, publisher={Informa UK Limited}, author={Chormey,
    Dotse Selali and Tonbul, Güldeniz and Soylu, Güneş and Saygılar, Ahmet and Bakırdere,
    Sezgin}, year={2021}, pages={237–245} }'
  chicago: 'Chormey, Dotse Selali, Güldeniz Tonbul, Güneş Soylu, Ahmet Saygılar, and
    Sezgin Bakırdere. “Determination of Four Priority Polycyclic Aromatic Hydrocarbons
    in Food Samples by Gas Chromatography – Mass Spectrometry (GC-MS) after Vortex
    Assisted Dispersive Liquid-Liquid Microextraction (DLLME).” <i>Analytical Letters</i>
    55, no. 2 (2021): 237–45. <a href="https://doi.org/10.1080/00032719.2021.1922432">https://doi.org/10.1080/00032719.2021.1922432</a>.'
  ieee: 'D. S. Chormey, G. Tonbul, G. Soylu, A. Saygılar, and S. Bakırdere, “Determination
    of Four Priority Polycyclic Aromatic Hydrocarbons in Food Samples by Gas Chromatography
    – Mass Spectrometry (GC-MS) after Vortex Assisted Dispersive Liquid-Liquid Microextraction
    (DLLME),” <i>Analytical Letters</i>, vol. 55, no. 2, pp. 237–245, 2021, doi: <a
    href="https://doi.org/10.1080/00032719.2021.1922432">10.1080/00032719.2021.1922432</a>.'
  mla: Chormey, Dotse Selali, et al. “Determination of Four Priority Polycyclic Aromatic
    Hydrocarbons in Food Samples by Gas Chromatography – Mass Spectrometry (GC-MS)
    after Vortex Assisted Dispersive Liquid-Liquid Microextraction (DLLME).” <i>Analytical
    Letters</i>, vol. 55, no. 2, Informa UK Limited, 2021, pp. 237–45, doi:<a href="https://doi.org/10.1080/00032719.2021.1922432">10.1080/00032719.2021.1922432</a>.
  short: D.S. Chormey, G. Tonbul, G. Soylu, A. Saygılar, S. Bakırdere, Analytical
    Letters 55 (2021) 237–245.
date_created: 2023-05-03T08:13:58Z
date_updated: 2023-05-03T08:26:30Z
doi: 10.1080/00032719.2021.1922432
intvolume: '        55'
issue: '2'
keyword:
- Dispersive liquid-liquid microextraction (DLLME)
- gas chromatography – mass spectrometry (GC-MS)
- polycyclic aromatic hydrocarbons
- QuEChERS
language:
- iso: eng
page: 237-245
publication: Analytical Letters
publication_identifier:
  issn:
  - 0003-2719
  - 1532-236X
publication_status: published
publisher: Informa UK Limited
status: public
title: Determination of Four Priority Polycyclic Aromatic Hydrocarbons in Food Samples
  by Gas Chromatography – Mass Spectrometry (GC-MS) after Vortex Assisted Dispersive
  Liquid-Liquid Microextraction (DLLME)
type: journal_article
user_id: '89054'
volume: 55
year: '2021'
...
---
_id: '61024'
abstract:
- lang: eng
  text: "Background: The evolution of primate sexual swellings and their influence
    on mating strategies have captivated the\r\ninterest of biologists for over a
    century. Across the primate order, variability in the timing of ovulation with
    respect to\r\nfemales’ sexual swelling patterns differs greatly. Since sexual
    swellings typically function as signals of female fecundity,\r\nthe temporal relation
    between ovulation and sexual swellings can impact the ability of males to pinpoint
    ovulation\r\nand thereby affect male mating strategies. Here, we used endocrine
    parameters to detect ovulation and examined the\r\ntemporal relation between the
    maximum swelling phase (MSP) and ovulation in wild female bonobos (Pan paniscus).\r\nData
    were collected at the Luikotale field site, Democratic Republic of Congo, spanning
    36 months. Observational data\r\nfrom 13 females were used to characterise female
    swelling cycles (N = 70). Furthermore, we measured urinary oestrone\r\nand pregnanediol
    using liquid chromatography–tandem mass spectrometry, and used pregnanediol to
    determine the\r\ntiming of ovulation in 34 cycles (N = 9 females).\r\nResults:
    We found that the duration of females’ MSP was highly variable, ranging from 1
    to 31 days. Timing of ovulation\r\nvaried considerably in relation to the onset
    of the MSP, resulting in a very low day-specific probability of ovulation and\r\nfecundity
    across female cycles. Ovulation occurred during the MSP in only 52.9 % of the
    analysed swelling cycles, and\r\nfemales showed regular sexual swelling patterns
    in N = 8 swelling cycles where ovulation did not occur. These findings\r\nreveal
    that sexual swellings of bonobos are less reliable indicators of ovulation compared
    to other species of primates.\r\nConclusions: Female bonobos show unusual variability
    in the duration of the MSP and in the timing of ovulation\r\nrelative to the sexual
    swelling signal. These data are important for understanding the evolution of sexual
    signals, how\r\nthey influence male and female mating strategies, and how decoupling
    visual signals of fecundity from the periovulatory\r\nperiod may affect intersexual
    conflict. By prolonging the period during which males would need to mate guard
    females\r\nto ascertain paternity, the temporal variability of this signal may
    constrain mate-guarding efforts by male bonobos."
article_number: '140'
article_type: original
author:
- first_name: Pamela Heidi
  full_name: Douglas, Pamela Heidi
  id: '72311'
  last_name: Douglas
- first_name: Gottfried
  full_name: Hohmann, Gottfried
  last_name: Hohmann
- first_name: Róisín
  full_name: Murtagh, Róisín
  last_name: Murtagh
- first_name: Robyn
  full_name: Thiessen-Bock, Robyn
  last_name: Thiessen-Bock
- first_name: Tobias
  full_name: Deschner, Tobias
  last_name: Deschner
citation:
  ama: 'Douglas PH, Hohmann G, Murtagh R, Thiessen-Bock R, Deschner T. Mixed messages:
    wild female bonobos show high variability in the timing of ovulation in relation
    to sexual swelling patterns. <i>BMC Evolutionary Biology</i>. 2016;16(1). doi:<a
    href="https://doi.org/10.1186/s12862-016-0691-3">10.1186/s12862-016-0691-3</a>'
  apa: 'Douglas, P. H., Hohmann, G., Murtagh, R., Thiessen-Bock, R., &#38; Deschner,
    T. (2016). Mixed messages: wild female bonobos show high variability in the timing
    of ovulation in relation to sexual swelling patterns. <i>BMC Evolutionary Biology</i>,
    <i>16</i>(1), Article 140. <a href="https://doi.org/10.1186/s12862-016-0691-3">https://doi.org/10.1186/s12862-016-0691-3</a>'
  bibtex: '@article{Douglas_Hohmann_Murtagh_Thiessen-Bock_Deschner_2016, title={Mixed
    messages: wild female bonobos show high variability in the timing of ovulation
    in relation to sexual swelling patterns}, volume={16}, DOI={<a href="https://doi.org/10.1186/s12862-016-0691-3">10.1186/s12862-016-0691-3</a>},
    number={1140}, journal={BMC Evolutionary Biology}, publisher={Springer Science
    and Business Media LLC}, author={Douglas, Pamela Heidi and Hohmann, Gottfried
    and Murtagh, Róisín and Thiessen-Bock, Robyn and Deschner, Tobias}, year={2016}
    }'
  chicago: 'Douglas, Pamela Heidi, Gottfried Hohmann, Róisín Murtagh, Robyn Thiessen-Bock,
    and Tobias Deschner. “Mixed Messages: Wild Female Bonobos Show High Variability
    in the Timing of Ovulation in Relation to Sexual Swelling Patterns.” <i>BMC Evolutionary
    Biology</i> 16, no. 1 (2016). <a href="https://doi.org/10.1186/s12862-016-0691-3">https://doi.org/10.1186/s12862-016-0691-3</a>.'
  ieee: 'P. H. Douglas, G. Hohmann, R. Murtagh, R. Thiessen-Bock, and T. Deschner,
    “Mixed messages: wild female bonobos show high variability in the timing of ovulation
    in relation to sexual swelling patterns,” <i>BMC Evolutionary Biology</i>, vol.
    16, no. 1, Art. no. 140, 2016, doi: <a href="https://doi.org/10.1186/s12862-016-0691-3">10.1186/s12862-016-0691-3</a>.'
  mla: 'Douglas, Pamela Heidi, et al. “Mixed Messages: Wild Female Bonobos Show High
    Variability in the Timing of Ovulation in Relation to Sexual Swelling Patterns.”
    <i>BMC Evolutionary Biology</i>, vol. 16, no. 1, 140, Springer Science and Business
    Media LLC, 2016, doi:<a href="https://doi.org/10.1186/s12862-016-0691-3">10.1186/s12862-016-0691-3</a>.'
  short: P.H. Douglas, G. Hohmann, R. Murtagh, R. Thiessen-Bock, T. Deschner, BMC
    Evolutionary Biology 16 (2016).
date_created: 2025-08-26T19:10:36Z
date_updated: 2025-08-26T19:52:41Z
department:
- _id: '40'
doi: 10.1186/s12862-016-0691-3
extern: '1'
intvolume: '        16'
issue: '1'
keyword:
- Primate
- Sexual signalling
- Fecundity
- Endocrine analysis
- LC–MS/MS
- Estrogen
- Pan paniscus
- Pregnanediol
- Mate guarding
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-016-0691-3
oa: '1'
publication: BMC Evolutionary Biology
publication_identifier:
  issn:
  - 1471-2148
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: 'Mixed messages: wild female bonobos show high variability in the timing of
  ovulation in relation to sexual swelling patterns'
type: journal_article
user_id: '72311'
volume: 16
year: '2016'
...