---
_id: '51121'
abstract:
- lang: eng
text: DNA origami nanostructures are a powerful tool in biomedicine and
can be used to combat drug‐resistant bacterial infections. However, the effect
of unmodified DNA origami nanostructures on bacteria is yet to be elucidated.
With the aim to obtain a better understanding of this phenomenon, the effect of
three DNA origami shapes, i.e., DNA origami triangles, six‐helix bundles (6HBs),
and 24‐helix bundles (24HBs), on the growth of Gram‐negative Escherichia coli
and Gram‐positive Bacillus subtilis is investigated. These results reveal that
while triangles and 24HBs can be used as a source of nutrients by E. coli and
thereby promote population growth, their effect is much smaller than that of genomic
single‐ and double‐stranded DNA. However, no effect on E. coli population growth
is observed for the 6HBs. On the other hand, B. subtilis does not show any significant
changes in population growth when cultured with the different DNA origami shapes
or genomic DNA. The detailed effect of DNA origami nanostructures on bacterial
growth thus depends on the competence signals and uptake mechanism of each bacterial
species, as well as the DNA origami shape. This should be considered in the development
of antimicrobial DNA origami nanostructures.
author:
- first_name: Jaime Andres
full_name: Garcia-Diosa, Jaime Andres
last_name: Garcia-Diosa
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Garcia-Diosa JA, Grundmeier G, Keller A. Effect of DNA Origami Nanostructures
on Bacterial Growth. ChemBioChem. Published online 2024. doi:10.1002/cbic.202400091
apa: Garcia-Diosa, J. A., Grundmeier, G., & Keller, A. (2024). Effect of DNA
Origami Nanostructures on Bacterial Growth. ChemBioChem. https://doi.org/10.1002/cbic.202400091
bibtex: '@article{Garcia-Diosa_Grundmeier_Keller_2024, title={Effect of DNA Origami
Nanostructures on Bacterial Growth}, DOI={10.1002/cbic.202400091},
journal={ChemBioChem}, publisher={Wiley}, author={Garcia-Diosa, Jaime Andres and
Grundmeier, Guido and Keller, Adrian}, year={2024} }'
chicago: Garcia-Diosa, Jaime Andres, Guido Grundmeier, and Adrian Keller. “Effect
of DNA Origami Nanostructures on Bacterial Growth.” ChemBioChem, 2024.
https://doi.org/10.1002/cbic.202400091.
ieee: 'J. A. Garcia-Diosa, G. Grundmeier, and A. Keller, “Effect of DNA Origami
Nanostructures on Bacterial Growth,” ChemBioChem, 2024, doi: 10.1002/cbic.202400091.'
mla: Garcia-Diosa, Jaime Andres, et al. “Effect of DNA Origami Nanostructures on
Bacterial Growth.” ChemBioChem, Wiley, 2024, doi:10.1002/cbic.202400091.
short: J.A. Garcia-Diosa, G. Grundmeier, A. Keller, ChemBioChem (2024).
date_created: 2024-02-03T12:41:16Z
date_updated: 2024-02-03T12:42:48Z
department:
- _id: '302'
doi: 10.1002/cbic.202400091
keyword:
- Organic Chemistry
- Molecular Biology
- Molecular Medicine
- Biochemistry
language:
- iso: eng
publication: ChemBioChem
publication_identifier:
issn:
- 1439-4227
- 1439-7633
publication_status: published
publisher: Wiley
status: public
title: Effect of DNA Origami Nanostructures on Bacterial Growth
type: journal_article
user_id: '48864'
year: '2024'
...
---
_id: '52541'
abstract:
- lang: eng
text: AbstractWe conducted an investigation into
the palladium‐catalyzed carbon‐sulfur cross‐coupling reaction involving a 2‐bromothiophene
derivative and potassium thioacetate as a substitute for hydrogen sulfide. This
investigation utilized kinetic and computational methods. We synthesized two palladium
complexes supported by the bisphosphane ligands bis(diphenylphosphino)ferrocene
(DPPF) and bis(diisopropylphosphino)ferrocene (DiPPF),
as well as their tentative intermediates in the catalytic cycle. Reaction rates
were measured and then compared to computational predictions.
author:
- first_name: Sebastian
full_name: Peschtrich, Sebastian
last_name: Peschtrich
- first_name: Roland
full_name: Schoch, Roland
id: '48467'
last_name: Schoch
orcid: 0000-0003-2061-7289
- first_name: Dirk
full_name: Kuckling, Dirk
id: '287'
last_name: Kuckling
- first_name: Jan
full_name: Paradies, Jan
id: '53339'
last_name: Paradies
orcid: 0000-0002-3698-668X
citation:
ama: Peschtrich S, Schoch R, Kuckling D, Paradies J. A Comparative Kinetic and Computational
Investigation of the Carbon‐Sulfur Cross Coupling of Potassium Thioacetate and
2‐Bromo Thiophene Using Palladium/Bisphosphine Complexes. European Journal
of Organic Chemistry. 2024;27(8). doi:10.1002/ejoc.202301207
apa: Peschtrich, S., Schoch, R., Kuckling, D., & Paradies, J. (2024). A Comparative
Kinetic and Computational Investigation of the Carbon‐Sulfur Cross Coupling of
Potassium Thioacetate and 2‐Bromo Thiophene Using Palladium/Bisphosphine Complexes.
European Journal of Organic Chemistry, 27(8). https://doi.org/10.1002/ejoc.202301207
bibtex: '@article{Peschtrich_Schoch_Kuckling_Paradies_2024, title={A Comparative
Kinetic and Computational Investigation of the Carbon‐Sulfur Cross Coupling of
Potassium Thioacetate and 2‐Bromo Thiophene Using Palladium/Bisphosphine Complexes},
volume={27}, DOI={10.1002/ejoc.202301207},
number={8}, journal={European Journal of Organic Chemistry}, publisher={Wiley},
author={Peschtrich, Sebastian and Schoch, Roland and Kuckling, Dirk and Paradies,
Jan}, year={2024} }'
chicago: Peschtrich, Sebastian, Roland Schoch, Dirk Kuckling, and Jan Paradies.
“A Comparative Kinetic and Computational Investigation of the Carbon‐Sulfur Cross
Coupling of Potassium Thioacetate and 2‐Bromo Thiophene Using Palladium/Bisphosphine
Complexes.” European Journal of Organic Chemistry 27, no. 8 (2024). https://doi.org/10.1002/ejoc.202301207.
ieee: 'S. Peschtrich, R. Schoch, D. Kuckling, and J. Paradies, “A Comparative Kinetic
and Computational Investigation of the Carbon‐Sulfur Cross Coupling of Potassium
Thioacetate and 2‐Bromo Thiophene Using Palladium/Bisphosphine Complexes,” European
Journal of Organic Chemistry, vol. 27, no. 8, 2024, doi: 10.1002/ejoc.202301207.'
mla: Peschtrich, Sebastian, et al. “A Comparative Kinetic and Computational Investigation
of the Carbon‐Sulfur Cross Coupling of Potassium Thioacetate and 2‐Bromo Thiophene
Using Palladium/Bisphosphine Complexes.” European Journal of Organic Chemistry,
vol. 27, no. 8, Wiley, 2024, doi:10.1002/ejoc.202301207.
short: S. Peschtrich, R. Schoch, D. Kuckling, J. Paradies, European Journal of Organic
Chemistry 27 (2024).
date_created: 2024-03-13T17:15:14Z
date_updated: 2024-03-13T17:17:37Z
department:
- _id: '2'
- _id: '389'
doi: 10.1002/ejoc.202301207
intvolume: ' 27'
issue: '8'
keyword:
- Organic Chemistry
- Physical and Theoretical Chemistry
language:
- iso: eng
publication: European Journal of Organic Chemistry
publication_identifier:
issn:
- 1434-193X
- 1099-0690
publication_status: published
publisher: Wiley
status: public
title: A Comparative Kinetic and Computational Investigation of the Carbon‐Sulfur
Cross Coupling of Potassium Thioacetate and 2‐Bromo Thiophene Using Palladium/Bisphosphine
Complexes
type: journal_article
user_id: '53339'
volume: 27
year: '2024'
...
---
_id: '53163'
abstract:
- lang: eng
text: An SPR-based dually crosslinked gel sensor for adiponitrile bearing
pillar[5]arene responsive sites with a low limit of detection was developed.
article_type: original
author:
- first_name: Maksim
full_name: Rodin, Maksim
last_name: Rodin
- first_name: David
full_name: Helle, David
last_name: Helle
- first_name: Dirk
full_name: Kuckling, Dirk
id: '287'
last_name: Kuckling
citation:
ama: Rodin M, Helle D, Kuckling D. Pillar[5]arene-based dually crosslinked supramolecular
gel as a sensor for the detection of adiponitrile. Polymer Chemistry. 2024;15(7):661-679.
doi:10.1039/d3py01354e
apa: Rodin, M., Helle, D., & Kuckling, D. (2024). Pillar[5]arene-based dually
crosslinked supramolecular gel as a sensor for the detection of adiponitrile.
Polymer Chemistry, 15(7), 661–679. https://doi.org/10.1039/d3py01354e
bibtex: '@article{Rodin_Helle_Kuckling_2024, title={Pillar[5]arene-based dually
crosslinked supramolecular gel as a sensor for the detection of adiponitrile},
volume={15}, DOI={10.1039/d3py01354e},
number={7}, journal={Polymer Chemistry}, publisher={Royal Society of Chemistry
(RSC)}, author={Rodin, Maksim and Helle, David and Kuckling, Dirk}, year={2024},
pages={661–679} }'
chicago: 'Rodin, Maksim, David Helle, and Dirk Kuckling. “Pillar[5]Arene-Based Dually
Crosslinked Supramolecular Gel as a Sensor for the Detection of Adiponitrile.”
Polymer Chemistry 15, no. 7 (2024): 661–79. https://doi.org/10.1039/d3py01354e.'
ieee: 'M. Rodin, D. Helle, and D. Kuckling, “Pillar[5]arene-based dually crosslinked
supramolecular gel as a sensor for the detection of adiponitrile,” Polymer
Chemistry, vol. 15, no. 7, pp. 661–679, 2024, doi: 10.1039/d3py01354e.'
mla: Rodin, Maksim, et al. “Pillar[5]Arene-Based Dually Crosslinked Supramolecular
Gel as a Sensor for the Detection of Adiponitrile.” Polymer Chemistry,
vol. 15, no. 7, Royal Society of Chemistry (RSC), 2024, pp. 661–79, doi:10.1039/d3py01354e.
short: M. Rodin, D. Helle, D. Kuckling, Polymer Chemistry 15 (2024) 661–679.
date_created: 2024-04-03T10:57:17Z
date_updated: 2024-04-03T11:03:03Z
department:
- _id: '163'
doi: 10.1039/d3py01354e
intvolume: ' 15'
issue: '7'
keyword:
- Organic Chemistry
- Polymers and Plastics
- Biochemistry
- Bioengineering
language:
- iso: eng
page: 661-679
publication: Polymer Chemistry
publication_identifier:
issn:
- 1759-9954
- 1759-9962
publication_status: published
publisher: Royal Society of Chemistry (RSC)
status: public
title: Pillar[5]arene-based dually crosslinked supramolecular gel as a sensor for
the detection of adiponitrile
type: journal_article
user_id: '94'
volume: 15
year: '2024'
...
---
_id: '48588'
abstract:
- lang: eng
text: Bacterial colonization and biofilm formation on abiotic surfaces are
initiated by the adhesion of peptides and proteins. Understanding the adhesion
of such peptides and proteins at a molecular level thus represents an important
step toward controlling and suppressing biofilm formation on technological and
medical materials. This study investigates the molecular adhesion of a pilus‐derived
peptide that facilitates biofilm formation of Pseudomonas aeruginosa, a multidrug‐resistant
opportunistic pathogen frequently encountered in healthcare settings. Single‐molecule
force spectroscopy (SMFS) was performed on chemically etched ZnO surfaces to gather
insights about peptide adsorption force and its kinetics. Metal‐free click chemistry
for the fabrication of peptide‐terminated SMFS cantilevers was performed on amine‐terminated
gold cantilevers and verified by X‐ray photoelectron spectroscopy (XPS) and polarization‐modulated
infrared reflection absorption spectroscopy (PM‐IRRAS). Atomic force microscopy
(AFM) and XPS analyses reveal stable topographies and surface chemistries of the
substrates that are not affected by SMFS. Rupture events described by the worm‐like
chain model (WLC) up to 600 pN were detected for the non‐polar ZnO(11‐20) surfaces.
The dissociation barrier energy at zero force ΔG(0), the transition state distance
xb and bound‐unbound dissociation rate at zero force koff(0) for the single crystalline
substrate indicate that coordination and hydrogen bonds dominate the peptide/surface
interaction.
author:
- first_name: Tim
full_name: Prüßner, Tim
last_name: Prüßner
- first_name: Dennis
full_name: Meinderink, Dennis
id: '32378'
last_name: Meinderink
orcid: 0000-0002-2755-6514
- first_name: Siqi
full_name: Zhu, Siqi
last_name: Zhu
- first_name: Alejandro G.
full_name: Orive, Alejandro G.
last_name: Orive
- first_name: Charlotte
full_name: Kielar, Charlotte
last_name: Kielar
- first_name: Marten
full_name: Huck, Marten
last_name: Huck
- first_name: Hans-Georg
full_name: Steinrück, Hans-Georg
id: '84268'
last_name: Steinrück
orcid: 0000-0001-6373-0877
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
citation:
ama: Prüßner T, Meinderink D, Zhu S, et al. Molecular Adhesion of a Pilus‐derived
Peptide Involved in Pseudomonas aeruginosa Biofilm Formation on non‐polar ZnO
Surfaces. Chemistry – A European Journal. Published online 2023. doi:10.1002/chem.202302464
apa: Prüßner, T., Meinderink, D., Zhu, S., Orive, A. G., Kielar, C., Huck, M., Steinrück,
H.-G., Keller, A., & Grundmeier, G. (2023). Molecular Adhesion of a Pilus‐derived
Peptide Involved in Pseudomonas aeruginosa Biofilm Formation on non‐polar ZnO
Surfaces. Chemistry – A European Journal. https://doi.org/10.1002/chem.202302464
bibtex: '@article{Prüßner_Meinderink_Zhu_Orive_Kielar_Huck_Steinrück_Keller_Grundmeier_2023,
title={Molecular Adhesion of a Pilus‐derived Peptide Involved in Pseudomonas aeruginosa
Biofilm Formation on non‐polar ZnO Surfaces}, DOI={10.1002/chem.202302464},
journal={Chemistry – A European Journal}, publisher={Wiley}, author={Prüßner,
Tim and Meinderink, Dennis and Zhu, Siqi and Orive, Alejandro G. and Kielar, Charlotte
and Huck, Marten and Steinrück, Hans-Georg and Keller, Adrian and Grundmeier,
Guido}, year={2023} }'
chicago: Prüßner, Tim, Dennis Meinderink, Siqi Zhu, Alejandro G. Orive, Charlotte
Kielar, Marten Huck, Hans-Georg Steinrück, Adrian Keller, and Guido Grundmeier.
“Molecular Adhesion of a Pilus‐derived Peptide Involved in Pseudomonas Aeruginosa
Biofilm Formation on Non‐polar ZnO Surfaces.” Chemistry – A European Journal,
2023. https://doi.org/10.1002/chem.202302464.
ieee: 'T. Prüßner et al., “Molecular Adhesion of a Pilus‐derived Peptide
Involved in Pseudomonas aeruginosa Biofilm Formation on non‐polar ZnO Surfaces,”
Chemistry – A European Journal, 2023, doi: 10.1002/chem.202302464.'
mla: Prüßner, Tim, et al. “Molecular Adhesion of a Pilus‐derived Peptide Involved
in Pseudomonas Aeruginosa Biofilm Formation on Non‐polar ZnO Surfaces.” Chemistry
– A European Journal, Wiley, 2023, doi:10.1002/chem.202302464.
short: T. Prüßner, D. Meinderink, S. Zhu, A.G. Orive, C. Kielar, M. Huck, H.-G.
Steinrück, A. Keller, G. Grundmeier, Chemistry – A European Journal (2023).
date_created: 2023-11-02T09:23:41Z
date_updated: 2023-11-02T09:26:00Z
department:
- _id: '302'
- _id: '633'
doi: 10.1002/chem.202302464
keyword:
- General Chemistry
- Catalysis
- Organic Chemistry
language:
- iso: eng
publication: Chemistry – A European Journal
publication_identifier:
issn:
- 0947-6539
- 1521-3765
publication_status: published
publisher: Wiley
status: public
title: Molecular Adhesion of a Pilus‐derived Peptide Involved in Pseudomonas aeruginosa
Biofilm Formation on non‐polar ZnO Surfaces
type: journal_article
user_id: '48864'
year: '2023'
...
---
_id: '50150'
abstract:
- lang: eng
text: Covalent peptidomimetic protease inhibitors have gained a lot of attention
in drug development in recent years. They are designed to covalently bind the
catalytically active amino acids through electrophilic groups called warheads.
Covalent inhibition has an advantage in terms of pharmacodynamic properties but
can also bear toxicity risks due to non-selective off-target protein binding.
Therefore, the right combination of a reactive warhead with a well-suited peptidomimetic
sequence is of great importance. Herein, the selectivities of well-known warheads
combined with peptidomimetic sequences suited for five different proteases were
investigated, highlighting the impact of both structure parts (warhead and peptidomimetic
sequence) for affinity and selectivity. Molecular docking gave insights into the
predicted binding modes of the inhibitors inside the binding pockets of the different
enzymes. Moreover, the warheads were investigated by NMR and LC-MS reactivity
assays against serine/threonine and cysteine nucleophile models, as well as by
quantum mechanics simulations.
article_number: '7226'
author:
- first_name: Patrick
full_name: Müller, Patrick
last_name: Müller
- first_name: Mergim
full_name: Meta, Mergim
last_name: Meta
- first_name: Jan Laurenz
full_name: Meidner, Jan Laurenz
last_name: Meidner
- first_name: Marvin
full_name: Schwickert, Marvin
last_name: Schwickert
- first_name: Jessica
full_name: Meyr, Jessica
last_name: Meyr
- first_name: Kevin
full_name: Schwickert, Kevin
last_name: Schwickert
- first_name: Christian
full_name: Kersten, Christian
last_name: Kersten
- first_name: Collin
full_name: Zimmer, Collin
last_name: Zimmer
- first_name: Stefan Josef
full_name: Hammerschmidt, Stefan Josef
last_name: Hammerschmidt
- first_name: Ariane
full_name: Frey, Ariane
last_name: Frey
- first_name: Albin
full_name: Lahu, Albin
last_name: Lahu
- first_name: Sergio
full_name: de la Hoz-Rodríguez, Sergio
last_name: de la Hoz-Rodríguez
- first_name: Laura
full_name: Agost-Beltrán, Laura
last_name: Agost-Beltrán
- first_name: Santiago
full_name: Rodríguez, Santiago
last_name: Rodríguez
- first_name: Kira
full_name: Diemer, Kira
last_name: Diemer
- first_name: Wilhelm
full_name: Neumann, Wilhelm
last_name: Neumann
- first_name: Florenci V.
full_name: Gonzàlez, Florenci V.
last_name: Gonzàlez
- first_name: Bernd
full_name: Engels, Bernd
last_name: Engels
- first_name: Tanja
full_name: Schirmeister, Tanja
last_name: Schirmeister
citation:
ama: Müller P, Meta M, Meidner JL, et al. Investigation of the Compatibility between
Warheads and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive Reactivity
and Selectivity Study. International Journal of Molecular Sciences. 2023;24(8).
doi:10.3390/ijms24087226
apa: Müller, P., Meta, M., Meidner, J. L., Schwickert, M., Meyr, J., Schwickert,
K., Kersten, C., Zimmer, C., Hammerschmidt, S. J., Frey, A., Lahu, A., de la Hoz-Rodríguez,
S., Agost-Beltrán, L., Rodríguez, S., Diemer, K., Neumann, W., Gonzàlez, F. V.,
Engels, B., & Schirmeister, T. (2023). Investigation of the Compatibility
between Warheads and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive
Reactivity and Selectivity Study. International Journal of Molecular Sciences,
24(8), Article 7226. https://doi.org/10.3390/ijms24087226
bibtex: '@article{Müller_Meta_Meidner_Schwickert_Meyr_Schwickert_Kersten_Zimmer_Hammerschmidt_Frey_et
al._2023, title={Investigation of the Compatibility between Warheads and Peptidomimetic
Sequences of Protease Inhibitors—A Comprehensive Reactivity and Selectivity Study},
volume={24}, DOI={10.3390/ijms24087226},
number={87226}, journal={International Journal of Molecular Sciences}, publisher={MDPI
AG}, author={Müller, Patrick and Meta, Mergim and Meidner, Jan Laurenz and Schwickert,
Marvin and Meyr, Jessica and Schwickert, Kevin and Kersten, Christian and Zimmer,
Collin and Hammerschmidt, Stefan Josef and Frey, Ariane and et al.}, year={2023}
}'
chicago: Müller, Patrick, Mergim Meta, Jan Laurenz Meidner, Marvin Schwickert, Jessica
Meyr, Kevin Schwickert, Christian Kersten, et al. “Investigation of the Compatibility
between Warheads and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive
Reactivity and Selectivity Study.” International Journal of Molecular Sciences
24, no. 8 (2023). https://doi.org/10.3390/ijms24087226.
ieee: 'P. Müller et al., “Investigation of the Compatibility between Warheads
and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive Reactivity
and Selectivity Study,” International Journal of Molecular Sciences, vol.
24, no. 8, Art. no. 7226, 2023, doi: 10.3390/ijms24087226.'
mla: Müller, Patrick, et al. “Investigation of the Compatibility between Warheads
and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive Reactivity
and Selectivity Study.” International Journal of Molecular Sciences, vol.
24, no. 8, 7226, MDPI AG, 2023, doi:10.3390/ijms24087226.
short: P. Müller, M. Meta, J.L. Meidner, M. Schwickert, J. Meyr, K. Schwickert,
C. Kersten, C. Zimmer, S.J. Hammerschmidt, A. Frey, A. Lahu, S. de la Hoz-Rodríguez,
L. Agost-Beltrán, S. Rodríguez, K. Diemer, W. Neumann, F.V. Gonzàlez, B. Engels,
T. Schirmeister, International Journal of Molecular Sciences 24 (2023).
date_created: 2024-01-04T08:24:31Z
date_updated: 2024-01-05T12:59:32Z
doi: 10.3390/ijms24087226
intvolume: ' 24'
issue: '8'
keyword:
- Inorganic Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Computer Science Applications
- Spectroscopy
- Molecular Biology
- General Medicine
- Catalysis
language:
- iso: eng
project:
- _id: '52'
name: 'PC2: Computing Resources Provided by the Paderborn Center for Parallel Computing'
publication: International Journal of Molecular Sciences
publication_identifier:
issn:
- 1422-0067
publication_status: published
publisher: MDPI AG
status: public
title: Investigation of the Compatibility between Warheads and Peptidomimetic Sequences
of Protease Inhibitors—A Comprehensive Reactivity and Selectivity Study
type: journal_article
user_id: '67287'
volume: 24
year: '2023'
...
---
_id: '46023'
abstract:
- lang: eng
text: This article presents the potential-dependent adsorption of two proteins,
bovine serum albumin (BSA) and lysozyme (LYZ), on Ti6Al4V alloy at pH 7.4 and
37 °C. The adsorption process was studied on an electropolished alloy under cathodic
and anodic overpotentials, compared to the open circuit potential (OCP). To analyze
the adsorption process, various complementary interface analytical techniques
were employed, including PM-IRRAS (polarization-modulation infrared reflection-absorption
spectroscopy), AFM (atomic force microscopy), XPS (X-ray photoelectron spectroscopy),
and E-QCM (electrochemical quartz crystal microbalance) measurements. The polarization
experiments were conducted within a potential range where charging of the electric
double layer dominates, and Faradaic currents can be disregarded. The findings
highlight the significant influence of the interfacial charge distribution on
the adsorption of BSA and LYZ onto the alloy surface. Furthermore, electrochemical
analysis of the protein layers formed under applied overpotentials demonstrated
improved corrosion protection properties. These studies provide valuable insights
into protein adsorption on titanium alloys under physiological conditions, characterized
by varying potentials of the passive alloy.
article_number: '5109'
author:
- first_name: Belma
full_name: Duderija, Belma
last_name: Duderija
- first_name: Alejandro
full_name: González-Orive, Alejandro
last_name: González-Orive
- first_name: Christoph
full_name: Ebbert, Christoph
last_name: Ebbert
- first_name: Vanessa
full_name: Neßlinger, Vanessa
last_name: Neßlinger
- first_name: Adrian
full_name: Keller, Adrian
last_name: Keller
- first_name: Guido
full_name: Grundmeier, Guido
last_name: Grundmeier
citation:
ama: Duderija B, González-Orive A, Ebbert C, Neßlinger V, Keller A, Grundmeier G.
Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy.
Molecules. 2023;28(13). doi:10.3390/molecules28135109
apa: Duderija, B., González-Orive, A., Ebbert, C., Neßlinger, V., Keller, A., &
Grundmeier, G. (2023). Electrode Potential-Dependent Studies of Protein Adsorption
on Ti6Al4V Alloy. Molecules, 28(13), Article 5109. https://doi.org/10.3390/molecules28135109
bibtex: '@article{Duderija_González-Orive_Ebbert_Neßlinger_Keller_Grundmeier_2023,
title={Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
Alloy}, volume={28}, DOI={10.3390/molecules28135109},
number={135109}, journal={Molecules}, publisher={MDPI AG}, author={Duderija, Belma
and González-Orive, Alejandro and Ebbert, Christoph and Neßlinger, Vanessa and
Keller, Adrian and Grundmeier, Guido}, year={2023} }'
chicago: Duderija, Belma, Alejandro González-Orive, Christoph Ebbert, Vanessa Neßlinger,
Adrian Keller, and Guido Grundmeier. “Electrode Potential-Dependent Studies of
Protein Adsorption on Ti6Al4V Alloy.” Molecules 28, no. 13 (2023). https://doi.org/10.3390/molecules28135109.
ieee: 'B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, and G.
Grundmeier, “Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
Alloy,” Molecules, vol. 28, no. 13, Art. no. 5109, 2023, doi: 10.3390/molecules28135109.'
mla: Duderija, Belma, et al. “Electrode Potential-Dependent Studies of Protein Adsorption
on Ti6Al4V Alloy.” Molecules, vol. 28, no. 13, 5109, MDPI AG, 2023, doi:10.3390/molecules28135109.
short: B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, G. Grundmeier,
Molecules 28 (2023).
date_created: 2023-07-12T07:55:40Z
date_updated: 2024-02-06T12:33:55Z
department:
- _id: '321'
- _id: '302'
doi: 10.3390/molecules28135109
intvolume: ' 28'
issue: '13'
keyword:
- Chemistry (miscellaneous)
- Analytical Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Molecular Medicine
- Drug Discovery
- Pharmaceutical Science
language:
- iso: eng
publication: Molecules
publication_identifier:
issn:
- 1420-3049
publication_status: published
publisher: MDPI AG
status: public
title: Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy
type: journal_article
user_id: '54863'
volume: 28
year: '2023'
...
---
_id: '48277'
abstract:
- lang: eng
text: AbstractCurrently, the fused deposition modeling
(FDM) process is the most common additive manufacturing technology. The principle
of the FDM process is the strand wise deposition of molten thermoplastic polymers,
by feeding a filament trough a heated nozzle. Due to the strand and layer wise
deposition the cooling of the manufactured component is not uniform. This leads
to dimensional deviations which may cause the component to be unusable for the
desired application. In this paper, a method is described which is based on the
shrinkage compensation through the adaption of every single raster line in components
manufactured with the FDM process. The shrinkage compensation is based on a model
resulting from a DOE which considers the main influencing factors on the shrinkage
behavior of raster lines in the FDM process. An in‐house developed software analyzes
the component and locally applies the shrinkage compensation with consideration
of the boundary conditions, e.g., the position of the raster line in the component
and the process parameters. Following, a validation using a simple geometry is
conducted to show the effect of the presented adaptive scaling method.
author:
- first_name: Elmar
full_name: Moritzer, Elmar
id: '20531'
last_name: Moritzer
- first_name: Felix
full_name: Hecker, Felix
id: '45537'
last_name: Hecker
citation:
ama: Moritzer E, Hecker F. Adaptive Scaling of Components in the Fused Deposition
Modeling Process. Macromolecular Symposia. 2023;411(1). doi:10.1002/masy.202200181
apa: Moritzer, E., & Hecker, F. (2023). Adaptive Scaling of Components in the
Fused Deposition Modeling Process. Macromolecular Symposia, 411(1).
https://doi.org/10.1002/masy.202200181
bibtex: '@article{Moritzer_Hecker_2023, title={Adaptive Scaling of Components in
the Fused Deposition Modeling Process}, volume={411}, DOI={10.1002/masy.202200181},
number={1}, journal={Macromolecular Symposia}, publisher={Wiley}, author={Moritzer,
Elmar and Hecker, Felix}, year={2023} }'
chicago: Moritzer, Elmar, and Felix Hecker. “Adaptive Scaling of Components in the
Fused Deposition Modeling Process.” Macromolecular Symposia 411, no. 1
(2023). https://doi.org/10.1002/masy.202200181.
ieee: 'E. Moritzer and F. Hecker, “Adaptive Scaling of Components in the Fused Deposition
Modeling Process,” Macromolecular Symposia, vol. 411, no. 1, 2023, doi:
10.1002/masy.202200181.'
mla: Moritzer, Elmar, and Felix Hecker. “Adaptive Scaling of Components in the Fused
Deposition Modeling Process.” Macromolecular Symposia, vol. 411, no. 1,
Wiley, 2023, doi:10.1002/masy.202200181.
short: E. Moritzer, F. Hecker, Macromolecular Symposia 411 (2023).
conference:
end_date: 2022-11-26
location: Bukarest
name: POLCOM 2022
start_date: 2022-11-13
date_created: 2023-10-19T07:25:06Z
date_updated: 2024-02-23T08:36:42Z
department:
- _id: '9'
- _id: '367'
- _id: '321'
- _id: '219'
- _id: '624'
doi: 10.1002/masy.202200181
intvolume: ' 411'
issue: '1'
keyword:
- Materials Chemistry
- Polymers and Plastics
- Organic Chemistry
- Condensed Matter Physics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/masy.202200181
oa: '1'
publication: Macromolecular Symposia
publication_identifier:
issn:
- 1022-1360
- 1521-3900
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Adaptive Scaling of Components in the Fused Deposition Modeling Process
type: journal_article
user_id: '45537'
volume: 411
year: '2023'
...
---
_id: '52542'
abstract:
- lang: eng
text: 'AbstractWe report on so‐called “hidden FLPs”
(FLP: frustrated Lewis pair) consisting of a phosphorus ylide featuring a group
13 fragment in the ortho position of a phenyl ring
scaffold to form five‐membered ring structures. Although the formation of the
Lewis acid/base adducts was observed in the solid state, most of the title compounds
readily react with carbon dioxide to provide stable insertion products. Strikingly,
0.3–3.0 mol% of the reported aluminum and gallium/carbon‐based ambiphiles catalyze
the reduction of CO2 to methanol with satisfactory high selectivity
and yields using pinacol borane as stoichiometric reduction equivalent. Comprehensive
computational studies provided valuable mechanistic insights and shed more light
on activity differences.'
author:
- first_name: Felix
full_name: Krämer, Felix
last_name: Krämer
- first_name: Jan
full_name: Paradies, Jan
id: '53339'
last_name: Paradies
orcid: 0000-0002-3698-668X
- first_name: Israel
full_name: Fernández, Israel
last_name: Fernández
- first_name: Frank
full_name: Breher, Frank
last_name: Breher
citation:
ama: 'Krämer F, Paradies J, Fernández I, Breher F. Quo Vadis CO2 Activation:
Catalytic Reduction of CO2 to Methanol Using Aluminum and Gallium/Carbon‐based
Ambiphiles. Chemistry – A European Journal. 2023;30(5). doi:10.1002/chem.202303380'
apa: 'Krämer, F., Paradies, J., Fernández, I., & Breher, F. (2023). Quo Vadis
CO2 Activation: Catalytic Reduction of CO2 to Methanol Using
Aluminum and Gallium/Carbon‐based Ambiphiles. Chemistry – A European Journal,
30(5). https://doi.org/10.1002/chem.202303380'
bibtex: '@article{Krämer_Paradies_Fernández_Breher_2023, title={Quo Vadis CO2
Activation: Catalytic Reduction of CO2 to Methanol Using Aluminum and
Gallium/Carbon‐based Ambiphiles}, volume={30}, DOI={10.1002/chem.202303380},
number={5}, journal={Chemistry – A European Journal}, publisher={Wiley}, author={Krämer,
Felix and Paradies, Jan and Fernández, Israel and Breher, Frank}, year={2023}
}'
chicago: 'Krämer, Felix, Jan Paradies, Israel Fernández, and Frank Breher. “Quo
Vadis CO2 Activation: Catalytic Reduction of CO2 to Methanol
Using Aluminum and Gallium/Carbon‐based Ambiphiles.” Chemistry – A European
Journal 30, no. 5 (2023). https://doi.org/10.1002/chem.202303380.'
ieee: 'F. Krämer, J. Paradies, I. Fernández, and F. Breher, “Quo Vadis CO2
Activation: Catalytic Reduction of CO2 to Methanol Using Aluminum and
Gallium/Carbon‐based Ambiphiles,” Chemistry – A European Journal, vol.
30, no. 5, 2023, doi: 10.1002/chem.202303380.'
mla: 'Krämer, Felix, et al. “Quo Vadis CO2 Activation: Catalytic Reduction
of CO2 to Methanol Using Aluminum and Gallium/Carbon‐based Ambiphiles.”
Chemistry – A European Journal, vol. 30, no. 5, Wiley, 2023, doi:10.1002/chem.202303380.'
short: F. Krämer, J. Paradies, I. Fernández, F. Breher, Chemistry – A European Journal
30 (2023).
date_created: 2024-03-13T17:17:52Z
date_updated: 2024-03-13T17:18:17Z
department:
- _id: '2'
- _id: '389'
doi: 10.1002/chem.202303380
intvolume: ' 30'
issue: '5'
keyword:
- General Chemistry
- Catalysis
- Organic Chemistry
language:
- iso: eng
publication: Chemistry – A European Journal
publication_identifier:
issn:
- 0947-6539
- 1521-3765
publication_status: published
publisher: Wiley
status: public
title: 'Quo Vadis CO2 Activation: Catalytic Reduction of CO2
to Methanol Using Aluminum and Gallium/Carbon‐based Ambiphiles'
type: journal_article
user_id: '53339'
volume: 30
year: '2023'
...
---
_id: '52802'
abstract:
- lang: eng
text: AbstractCurrently, the fused deposition modeling
(FDM) process is the most common additive manufacturing technology. The principle
of the FDM process is the strand wise deposition of molten thermoplastic polymers,
by feeding a filament trough a heated nozzle. Due to the strand and layer wise
deposition the cooling of the manufactured component is not uniform. This leads
to dimensional deviations which may cause the component to be unusable for the
desired application. In this paper, a method is described which is based on the
shrinkage compensation through the adaption of every single raster line in components
manufactured with the FDM process. The shrinkage compensation is based on a model
resulting from a DOE which considers the main influencing factors on the shrinkage
behavior of raster lines in the FDM process. An in‐house developed software analyzes
the component and locally applies the shrinkage compensation with consideration
of the boundary conditions, e.g., the position of the raster line in the component
and the process parameters. Following, a validation using a simple geometry is
conducted to show the effect of the presented adaptive scaling method.
author:
- first_name: Elmar
full_name: Moritzer, Elmar
id: '20531'
last_name: Moritzer
- first_name: Felix
full_name: Hecker, Felix
id: '45537'
last_name: Hecker
citation:
ama: Moritzer E, Hecker F. Adaptive Scaling of Components in the Fused Deposition
Modeling Process. Macromolecular Symposia. 2023;411(1). doi:10.1002/masy.202200181
apa: Moritzer, E., & Hecker, F. (2023). Adaptive Scaling of Components in the
Fused Deposition Modeling Process. Macromolecular Symposia, 411(1).
https://doi.org/10.1002/masy.202200181
bibtex: '@article{Moritzer_Hecker_2023, title={Adaptive Scaling of Components in
the Fused Deposition Modeling Process}, volume={411}, DOI={10.1002/masy.202200181},
number={1}, journal={Macromolecular Symposia}, publisher={Wiley}, author={Moritzer,
Elmar and Hecker, Felix}, year={2023} }'
chicago: Moritzer, Elmar, and Felix Hecker. “Adaptive Scaling of Components in the
Fused Deposition Modeling Process.” Macromolecular Symposia 411, no. 1
(2023). https://doi.org/10.1002/masy.202200181.
ieee: 'E. Moritzer and F. Hecker, “Adaptive Scaling of Components in the Fused Deposition
Modeling Process,” Macromolecular Symposia, vol. 411, no. 1, 2023, doi:
10.1002/masy.202200181.'
mla: Moritzer, Elmar, and Felix Hecker. “Adaptive Scaling of Components in the Fused
Deposition Modeling Process.” Macromolecular Symposia, vol. 411, no. 1,
Wiley, 2023, doi:10.1002/masy.202200181.
short: E. Moritzer, F. Hecker, Macromolecular Symposia 411 (2023).
date_created: 2024-03-25T09:16:46Z
date_updated: 2024-03-25T09:17:03Z
department:
- _id: '9'
- _id: '367'
- _id: '321'
doi: 10.1002/masy.202200181
intvolume: ' 411'
issue: '1'
keyword:
- Materials Chemistry
- Polymers and Plastics
- Organic Chemistry
- Condensed Matter Physics
language:
- iso: eng
publication: Macromolecular Symposia
publication_identifier:
issn:
- 1022-1360
- 1521-3900
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Adaptive Scaling of Components in the Fused Deposition Modeling Process
type: journal_article
user_id: '44116'
volume: 411
year: '2023'
...
---
_id: '53170'
abstract:
- lang: eng
text: AbstractCoating medical implants with antibacterial
polymers may prevent postoperative infections which are a common issue for conventional
titanium implants and can even lead to implant failure. Easily applicable diblock
copolymers are presented that form polymer brushes via “grafting to” mechanism
on titanium and equip the modified material with antibacterial properties. The
polymers carry quaternized pyridinium units to combat bacteria and phosphonic
acid groups which allow the linear chains to be anchored to metal surfaces in
a convenient coating process. The polymers are synthesized via reversible‐addition‐fragmentation‐chain‐transfer
(RAFT) polymerization and postmodifications and are characterized using NMR spectroscopy
and SEC. Low grafting densities are a major drawback of the “grafting to” approach
compared to “grafting from”. Thus, the number of phosphonic acid groups in the
anchor block are varied to investigate and optimize the surface binding. Modified
titanium surfaces are examined regarding their composition, wetting behavior,
streaming potential, and coating stability. Evaluation of the antimicrobial properties
revealed reduced bacterial adhesion and biofilm formation for certain polymers,
albeit the cell biocompatibility against human gingival fibroblasts is also impaired.
The presented findings show the potential of easy‐to‐apply polymer coatings and
aid in designing next‐generation implant surface modifications.
article_type: original
author:
- first_name: Rafael
full_name: Methling, Rafael
last_name: Methling
- first_name: Oliver
full_name: Dückmann, Oliver
last_name: Dückmann
- first_name: Frank
full_name: Simon, Frank
last_name: Simon
- first_name: Cornelia
full_name: Wolf‐Brandstetter, Cornelia
last_name: Wolf‐Brandstetter
- first_name: Dirk
full_name: Kuckling, Dirk
id: '287'
last_name: Kuckling
citation:
ama: Methling R, Dückmann O, Simon F, Wolf‐Brandstetter C, Kuckling D. Antimicrobial
Brushes on Titanium via “Grafting to” Using Phosphonic Acid/Pyridinium Containing
Block Copolymers. Macromolecular Materials and Engineering. 2023;308(8).
doi:10.1002/mame.202200665
apa: Methling, R., Dückmann, O., Simon, F., Wolf‐Brandstetter, C., & Kuckling,
D. (2023). Antimicrobial Brushes on Titanium via “Grafting to” Using Phosphonic
Acid/Pyridinium Containing Block Copolymers. Macromolecular Materials and Engineering,
308(8). https://doi.org/10.1002/mame.202200665
bibtex: '@article{Methling_Dückmann_Simon_Wolf‐Brandstetter_Kuckling_2023, title={Antimicrobial
Brushes on Titanium via “Grafting to” Using Phosphonic Acid/Pyridinium Containing
Block Copolymers}, volume={308}, DOI={10.1002/mame.202200665},
number={8}, journal={Macromolecular Materials and Engineering}, publisher={Wiley},
author={Methling, Rafael and Dückmann, Oliver and Simon, Frank and Wolf‐Brandstetter,
Cornelia and Kuckling, Dirk}, year={2023} }'
chicago: Methling, Rafael, Oliver Dückmann, Frank Simon, Cornelia Wolf‐Brandstetter,
and Dirk Kuckling. “Antimicrobial Brushes on Titanium via ‘Grafting to’ Using
Phosphonic Acid/Pyridinium Containing Block Copolymers.” Macromolecular Materials
and Engineering 308, no. 8 (2023). https://doi.org/10.1002/mame.202200665.
ieee: 'R. Methling, O. Dückmann, F. Simon, C. Wolf‐Brandstetter, and D. Kuckling,
“Antimicrobial Brushes on Titanium via ‘Grafting to’ Using Phosphonic Acid/Pyridinium
Containing Block Copolymers,” Macromolecular Materials and Engineering,
vol. 308, no. 8, 2023, doi: 10.1002/mame.202200665.'
mla: Methling, Rafael, et al. “Antimicrobial Brushes on Titanium via ‘Grafting to’
Using Phosphonic Acid/Pyridinium Containing Block Copolymers.” Macromolecular
Materials and Engineering, vol. 308, no. 8, Wiley, 2023, doi:10.1002/mame.202200665.
short: R. Methling, O. Dückmann, F. Simon, C. Wolf‐Brandstetter, D. Kuckling, Macromolecular
Materials and Engineering 308 (2023).
date_created: 2024-04-03T11:08:51Z
date_updated: 2024-04-03T11:10:05Z
department:
- _id: '163'
doi: 10.1002/mame.202200665
intvolume: ' 308'
issue: '8'
keyword:
- Materials Chemistry
- Polymers and Plastics
- Organic Chemistry
- General Chemical Engineering
language:
- iso: eng
publication: Macromolecular Materials and Engineering
publication_identifier:
issn:
- 1438-7492
- 1439-2054
publication_status: published
publisher: Wiley
status: public
title: Antimicrobial Brushes on Titanium via “Grafting to” Using Phosphonic Acid/Pyridinium
Containing Block Copolymers
type: journal_article
user_id: '94'
volume: 308
year: '2023'
...
---
_id: '52344'
abstract:
- lang: eng
text: Macrocyclization reactions are still challenging due to competing oligomerization,
which requires the use of small substrate concentrations. Here, the cationic tungsten
imido and tungsten oxo alkylidene N-heterocyclic carbene complexes [[W(N-2,6-Cl2-C6H3)(CHCMe2Ph(OC6F5)(pivalonitrile)(IMes)+
B(ArF)4−] (W1) and [W(O)(CHCMe2Ph(OCMe(CF3)2)(IMes)(CH3CN)+ B(ArF)4−] (W2) (IMes=1,3-dimesitylimidazol-2-ylidene;
B(ArF)4−=tetrakis(3,5-bis(trifluoromethyl)phenyl borate) have been immobilized
inside the pores of ordered mesoporous silica (OMS) with pore diameters of 3.3
and 6.8 nm, respectively, using a pore-selective immobilization protocol. X-ray
absorption spectroscopy of W1@OMS showed that even though the catalyst structure
is contracted due to confinement by the mesopores, both the oxidation state and
structure of the catalyst stayed intact upon immobilization. Catalytic testing
with four differently sized α,ω-dienes revealed a dramatically increased macrocyclization
(MC) and Z-selectivity of the supported catalysts compared to the homogenous progenitors,
allowing high substrate concentrations of 25 mM. With the supported complexes,
a maximum increase in MC-selectivity from 27 to 81 % and in Z-selectivity from
17 to 34 % was achieved. In general, smaller mesopores exhibited a stronger confinement
effect. A comparison of the two supported tungsten-based catalysts showed that
W1@OMS possesses a higher MC-selectivity, while W2@OMS exhibits a higher Z-selectivity
which can be rationalized by the structures of the catalysts.
article_type: original
author:
- first_name: Felix
full_name: Ziegler, Felix
last_name: Ziegler
- first_name: Johanna R.
full_name: Bruckner, Johanna R.
last_name: Bruckner
- first_name: Michał
full_name: Nowakowski, Michał
id: '78878'
last_name: Nowakowski
orcid: 0000-0002-3734-7011
- first_name: Matthias
full_name: Bauer, Matthias
id: '47241'
last_name: Bauer
orcid: 0000-0002-9294-6076
- first_name: Patrick
full_name: Probst, Patrick
last_name: Probst
- first_name: Boshra
full_name: Atwi, Boshra
last_name: Atwi
- first_name: Michael R.
full_name: Buchmeiser, Michael R.
last_name: Buchmeiser
citation:
ama: Ziegler F, Bruckner JR, Nowakowski M, et al. Macrocyclization of Dienes under
Confinement with Cationic Tungsten Imido/Oxo Alkylidene N‐Heterocyclic
Carbene Complexes. ChemCatChem. 2023;15(21). doi:10.1002/cctc.202300871
apa: Ziegler, F., Bruckner, J. R., Nowakowski, M., Bauer, M., Probst, P., Atwi,
B., & Buchmeiser, M. R. (2023). Macrocyclization of Dienes under Confinement
with Cationic Tungsten Imido/Oxo Alkylidene N‐Heterocyclic Carbene Complexes.
ChemCatChem, 15(21). https://doi.org/10.1002/cctc.202300871
bibtex: '@article{Ziegler_Bruckner_Nowakowski_Bauer_Probst_Atwi_Buchmeiser_2023,
title={Macrocyclization of Dienes under Confinement with Cationic Tungsten Imido/Oxo
Alkylidene N‐Heterocyclic Carbene Complexes}, volume={15}, DOI={10.1002/cctc.202300871},
number={21}, journal={ChemCatChem}, publisher={Wiley}, author={Ziegler, Felix
and Bruckner, Johanna R. and Nowakowski, Michał and Bauer, Matthias and Probst,
Patrick and Atwi, Boshra and Buchmeiser, Michael R.}, year={2023} }'
chicago: Ziegler, Felix, Johanna R. Bruckner, Michał Nowakowski, Matthias Bauer,
Patrick Probst, Boshra Atwi, and Michael R. Buchmeiser. “Macrocyclization of Dienes
under Confinement with Cationic Tungsten Imido/Oxo Alkylidene N‐Heterocyclic
Carbene Complexes.” ChemCatChem 15, no. 21 (2023). https://doi.org/10.1002/cctc.202300871.
ieee: 'F. Ziegler et al., “Macrocyclization of Dienes under Confinement with
Cationic Tungsten Imido/Oxo Alkylidene N‐Heterocyclic Carbene Complexes,”
ChemCatChem, vol. 15, no. 21, 2023, doi: 10.1002/cctc.202300871.'
mla: Ziegler, Felix, et al. “Macrocyclization of Dienes under Confinement with Cationic
Tungsten Imido/Oxo Alkylidene N‐Heterocyclic Carbene Complexes.” ChemCatChem,
vol. 15, no. 21, Wiley, 2023, doi:10.1002/cctc.202300871.
short: F. Ziegler, J.R. Bruckner, M. Nowakowski, M. Bauer, P. Probst, B. Atwi, M.R.
Buchmeiser, ChemCatChem 15 (2023).
date_created: 2024-03-07T09:44:33Z
date_updated: 2024-05-07T11:41:51Z
department:
- _id: '306'
doi: 10.1002/cctc.202300871
intvolume: ' 15'
issue: '21'
keyword:
- Inorganic Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Catalysis
language:
- iso: eng
publication: ChemCatChem
publication_identifier:
issn:
- 1867-3880
- 1867-3899
publication_status: published
publisher: Wiley
status: public
title: Macrocyclization of Dienes under Confinement with Cationic Tungsten Imido/Oxo
Alkylidene N‐Heterocyclic Carbene Complexes
type: journal_article
user_id: '48467'
volume: 15
year: '2023'
...
---
_id: '33447'
author:
- first_name: Sofia
full_name: Julin, Sofia
last_name: Julin
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Veikko
full_name: Linko, Veikko
last_name: Linko
citation:
ama: Julin S, Keller A, Linko V. Dynamics of DNA Origami Lattices. Bioconjugate
Chemistry. 2023;34:18-29. doi:10.1021/acs.bioconjchem.2c00359
apa: Julin, S., Keller, A., & Linko, V. (2023). Dynamics of DNA Origami Lattices.
Bioconjugate Chemistry, 34, 18–29. https://doi.org/10.1021/acs.bioconjchem.2c00359
bibtex: '@article{Julin_Keller_Linko_2023, title={Dynamics of DNA Origami Lattices},
volume={34}, DOI={10.1021/acs.bioconjchem.2c00359},
journal={Bioconjugate Chemistry}, publisher={American Chemical Society (ACS)},
author={Julin, Sofia and Keller, Adrian and Linko, Veikko}, year={2023}, pages={18–29}
}'
chicago: 'Julin, Sofia, Adrian Keller, and Veikko Linko. “Dynamics of DNA Origami
Lattices.” Bioconjugate Chemistry 34 (2023): 18–29. https://doi.org/10.1021/acs.bioconjchem.2c00359.'
ieee: 'S. Julin, A. Keller, and V. Linko, “Dynamics of DNA Origami Lattices,” Bioconjugate
Chemistry, vol. 34, pp. 18–29, 2023, doi: 10.1021/acs.bioconjchem.2c00359.'
mla: Julin, Sofia, et al. “Dynamics of DNA Origami Lattices.” Bioconjugate Chemistry,
vol. 34, American Chemical Society (ACS), 2023, pp. 18–29, doi:10.1021/acs.bioconjchem.2c00359.
short: S. Julin, A. Keller, V. Linko, Bioconjugate Chemistry 34 (2023) 18–29.
date_created: 2022-09-19T07:44:24Z
date_updated: 2023-01-18T08:31:47Z
department:
- _id: '302'
doi: 10.1021/acs.bioconjchem.2c00359
intvolume: ' 34'
keyword:
- Organic Chemistry
- Pharmaceutical Science
- Pharmacology
- Biomedical Engineering
- Bioengineering
- Biotechnology
language:
- iso: eng
page: 18-29
publication: Bioconjugate Chemistry
publication_identifier:
issn:
- 1043-1802
- 1520-4812
publication_status: published
publisher: American Chemical Society (ACS)
status: public
title: Dynamics of DNA Origami Lattices
type: journal_article
user_id: '48864'
volume: 34
year: '2023'
...
---
_id: '35693'
abstract:
- lang: eng
text: In recent years, frustrated Lewis pairs have been widely used in small
molecules activation and catalytic transformations. This graphic review is aimed
to provide the fundamental understanding of frustrated Lewis pair reactivity and
the exploitation thereof in catalytic reactions.
author:
- first_name: Rundong
full_name: Zhou, Rundong
last_name: Zhou
- first_name: Zoleykha
full_name: Tavandashti, Zoleykha
last_name: Tavandashti
- first_name: Jan
full_name: Paradies, Jan
id: '53339'
last_name: Paradies
orcid: 0000-0002-3698-668X
citation:
ama: Zhou R, Tavandashti Z, Paradies J. Frustrated Lewis Pair Catalysed Reactions.
SynOpen. Published online 2023. doi:10.1055/a-2005-5443
apa: Zhou, R., Tavandashti, Z., & Paradies, J. (2023). Frustrated Lewis Pair
Catalysed Reactions. SynOpen. https://doi.org/10.1055/a-2005-5443
bibtex: '@article{Zhou_Tavandashti_Paradies_2023, title={Frustrated Lewis Pair Catalysed
Reactions}, DOI={10.1055/a-2005-5443},
journal={SynOpen}, publisher={Georg Thieme Verlag KG}, author={Zhou, Rundong and
Tavandashti, Zoleykha and Paradies, Jan}, year={2023} }'
chicago: Zhou, Rundong, Zoleykha Tavandashti, and Jan Paradies. “Frustrated Lewis
Pair Catalysed Reactions.” SynOpen, 2023. https://doi.org/10.1055/a-2005-5443.
ieee: 'R. Zhou, Z. Tavandashti, and J. Paradies, “Frustrated Lewis Pair Catalysed
Reactions,” SynOpen, 2023, doi: 10.1055/a-2005-5443.'
mla: Zhou, Rundong, et al. “Frustrated Lewis Pair Catalysed Reactions.” SynOpen,
Georg Thieme Verlag KG, 2023, doi:10.1055/a-2005-5443.
short: R. Zhou, Z. Tavandashti, J. Paradies, SynOpen (2023).
date_created: 2023-01-10T08:58:57Z
date_updated: 2023-01-23T12:54:12Z
doi: 10.1055/a-2005-5443
keyword:
- Organic Chemistry
- Materials Science (miscellaneous)
- Biomaterials
- Catalysis
language:
- iso: eng
publication: SynOpen
publication_identifier:
issn:
- 2509-9396
publication_status: published
publisher: Georg Thieme Verlag KG
status: public
title: Frustrated Lewis Pair Catalysed Reactions
type: journal_article
user_id: '53339'
year: '2023'
...
---
_id: '42953'
author:
- first_name: Eleonora
full_name: Cara, Eleonora
last_name: Cara
- first_name: Philipp
full_name: Hönicke, Philipp
last_name: Hönicke
- first_name: Yves
full_name: Kayser, Yves
last_name: Kayser
- first_name: Jörg K. N.
full_name: Lindner, Jörg K. N.
id: '20797'
last_name: Lindner
- first_name: Micaela
full_name: Castellino, Micaela
last_name: Castellino
- first_name: Irdi
full_name: Murataj, Irdi
last_name: Murataj
- first_name: Samuele
full_name: Porro, Samuele
last_name: Porro
- first_name: Angelo
full_name: Angelini, Angelo
last_name: Angelini
- first_name: Natascia
full_name: De Leo, Natascia
last_name: De Leo
- first_name: Candido Fabrizio
full_name: Pirri, Candido Fabrizio
last_name: Pirri
- first_name: Burkhard
full_name: Beckhoff, Burkhard
last_name: Beckhoff
- first_name: Luca
full_name: Boarino, Luca
last_name: Boarino
- first_name: Federico
full_name: Ferrarese Lupi, Federico
last_name: Ferrarese Lupi
citation:
ama: 'Cara E, Hönicke P, Kayser Y, et al. Developing Quantitative Nondestructive
Characterization of Nanomaterials: A Case Study on Sequential Infiltration Synthesis
of Block Copolymers. ACS Applied Polymer Materials. 2023;5(3):2079-2087.
doi:10.1021/acsapm.2c02094'
apa: 'Cara, E., Hönicke, P., Kayser, Y., Lindner, J. K. N., Castellino, M., Murataj,
I., Porro, S., Angelini, A., De Leo, N., Pirri, C. F., Beckhoff, B., Boarino,
L., & Ferrarese Lupi, F. (2023). Developing Quantitative Nondestructive Characterization
of Nanomaterials: A Case Study on Sequential Infiltration Synthesis of Block Copolymers.
ACS Applied Polymer Materials, 5(3), 2079–2087. https://doi.org/10.1021/acsapm.2c02094'
bibtex: '@article{Cara_Hönicke_Kayser_Lindner_Castellino_Murataj_Porro_Angelini_De
Leo_Pirri_et al._2023, title={Developing Quantitative Nondestructive Characterization
of Nanomaterials: A Case Study on Sequential Infiltration Synthesis of Block Copolymers},
volume={5}, DOI={10.1021/acsapm.2c02094},
number={3}, journal={ACS Applied Polymer Materials}, publisher={American Chemical
Society (ACS)}, author={Cara, Eleonora and Hönicke, Philipp and Kayser, Yves and
Lindner, Jörg K. N. and Castellino, Micaela and Murataj, Irdi and Porro, Samuele
and Angelini, Angelo and De Leo, Natascia and Pirri, Candido Fabrizio and et al.},
year={2023}, pages={2079–2087} }'
chicago: 'Cara, Eleonora, Philipp Hönicke, Yves Kayser, Jörg K. N. Lindner, Micaela
Castellino, Irdi Murataj, Samuele Porro, et al. “Developing Quantitative Nondestructive
Characterization of Nanomaterials: A Case Study on Sequential Infiltration Synthesis
of Block Copolymers.” ACS Applied Polymer Materials 5, no. 3 (2023): 2079–87.
https://doi.org/10.1021/acsapm.2c02094.'
ieee: 'E. Cara et al., “Developing Quantitative Nondestructive Characterization
of Nanomaterials: A Case Study on Sequential Infiltration Synthesis of Block Copolymers,”
ACS Applied Polymer Materials, vol. 5, no. 3, pp. 2079–2087, 2023, doi:
10.1021/acsapm.2c02094.'
mla: 'Cara, Eleonora, et al. “Developing Quantitative Nondestructive Characterization
of Nanomaterials: A Case Study on Sequential Infiltration Synthesis of Block Copolymers.”
ACS Applied Polymer Materials, vol. 5, no. 3, American Chemical Society
(ACS), 2023, pp. 2079–87, doi:10.1021/acsapm.2c02094.'
short: E. Cara, P. Hönicke, Y. Kayser, J.K.N. Lindner, M. Castellino, I. Murataj,
S. Porro, A. Angelini, N. De Leo, C.F. Pirri, B. Beckhoff, L. Boarino, F. Ferrarese
Lupi, ACS Applied Polymer Materials 5 (2023) 2079–2087.
date_created: 2023-03-13T12:37:25Z
date_updated: 2023-03-13T12:39:28Z
department:
- _id: '15'
doi: 10.1021/acsapm.2c02094
intvolume: ' 5'
issue: '3'
keyword:
- Organic Chemistry
- Polymers and Plastics
- Process Chemistry and Technology
language:
- iso: eng
page: 2079-2087
publication: ACS Applied Polymer Materials
publication_identifier:
issn:
- 2637-6105
- 2637-6105
publication_status: published
publisher: American Chemical Society (ACS)
status: public
title: 'Developing Quantitative Nondestructive Characterization of Nanomaterials:
A Case Study on Sequential Infiltration Synthesis of Block Copolymers'
type: journal_article
user_id: '77496'
volume: 5
year: '2023'
...
---
_id: '44503'
author:
- first_name: Marcel
full_name: Hanke, Marcel
last_name: Hanke
- first_name: Emilia
full_name: Tomm, Emilia
last_name: Tomm
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Hanke M, Tomm E, Grundmeier G, Keller A. Effect of Ionic Strength on the Thermal
Stability of DNA Origami Nanostructures. ChemBioChem. Published online
2023. doi:10.1002/cbic.202300338
apa: Hanke, M., Tomm, E., Grundmeier, G., & Keller, A. (2023). Effect of Ionic
Strength on the Thermal Stability of DNA Origami Nanostructures. ChemBioChem.
https://doi.org/10.1002/cbic.202300338
bibtex: '@article{Hanke_Tomm_Grundmeier_Keller_2023, title={Effect of Ionic Strength
on the Thermal Stability of DNA Origami Nanostructures}, DOI={10.1002/cbic.202300338},
journal={ChemBioChem}, publisher={Wiley}, author={Hanke, Marcel and Tomm, Emilia
and Grundmeier, Guido and Keller, Adrian}, year={2023} }'
chicago: Hanke, Marcel, Emilia Tomm, Guido Grundmeier, and Adrian Keller. “Effect
of Ionic Strength on the Thermal Stability of DNA Origami Nanostructures.” ChemBioChem,
2023. https://doi.org/10.1002/cbic.202300338.
ieee: 'M. Hanke, E. Tomm, G. Grundmeier, and A. Keller, “Effect of Ionic Strength
on the Thermal Stability of DNA Origami Nanostructures,” ChemBioChem, 2023,
doi: 10.1002/cbic.202300338.'
mla: Hanke, Marcel, et al. “Effect of Ionic Strength on the Thermal Stability of
DNA Origami Nanostructures.” ChemBioChem, Wiley, 2023, doi:10.1002/cbic.202300338.
short: M. Hanke, E. Tomm, G. Grundmeier, A. Keller, ChemBioChem (2023).
date_created: 2023-05-05T10:47:29Z
date_updated: 2023-05-05T10:48:00Z
department:
- _id: '302'
doi: 10.1002/cbic.202300338
keyword:
- Organic Chemistry
- Molecular Biology
- Molecular Medicine
- Biochemistry
language:
- iso: eng
publication: ChemBioChem
publication_identifier:
issn:
- 1439-4227
- 1439-7633
publication_status: published
publisher: Wiley
status: public
title: Effect of Ionic Strength on the Thermal Stability of DNA Origami Nanostructures
type: journal_article
user_id: '48864'
year: '2023'
...
---
_id: '43827'
abstract:
- lang: eng
text: A series of new organic donor–π–acceptor dyes incorporating a diquat moiety
as a novel electron-acceptor unit have been synthesized and characterized. The
analytical data were supported by DFT calculations. These dyes were explored in
the aerobic thiocyanation of indoles and pyrroles. Here they showed a high photocatalytic
activity under visible light, giving isolated yields of up to 97 %. In addition,
the photocatalytic activity of standalone diquat and methyl viologen through formation
of an electron donor acceptor complex is presented.
article_type: original
author:
- first_name: Armin
full_name: Meier, Armin
last_name: Meier
- first_name: Sabuhi
full_name: Badalov, Sabuhi
id: '78800'
last_name: Badalov
orcid: 0000-0002-8481-4161
- first_name: Timur
full_name: Biktagirov, Timur
id: '65612'
last_name: Biktagirov
- first_name: Wolf Gero
full_name: Schmidt, Wolf Gero
id: '468'
last_name: Schmidt
orcid: 0000-0002-2717-5076
- first_name: René
full_name: Wilhelm, René
last_name: Wilhelm
citation:
ama: 'Meier A, Badalov S, Biktagirov T, Schmidt WG, Wilhelm R. Diquat Based Dyes:
A New Class of Photoredox Catalysts and Their Use in Aerobic Thiocyanation. Chemistry
– A European Journal. 2023;29(22):e202203541. doi:10.1002/chem.202203541'
apa: 'Meier, A., Badalov, S., Biktagirov, T., Schmidt, W. G., & Wilhelm, R.
(2023). Diquat Based Dyes: A New Class of Photoredox Catalysts and Their Use in
Aerobic Thiocyanation. Chemistry – A European Journal, 29(22), e202203541.
https://doi.org/10.1002/chem.202203541'
bibtex: '@article{Meier_Badalov_Biktagirov_Schmidt_Wilhelm_2023, title={Diquat Based
Dyes: A New Class of Photoredox Catalysts and Their Use in Aerobic Thiocyanation},
volume={29}, DOI={10.1002/chem.202203541},
number={22}, journal={Chemistry – A European Journal}, publisher={Wiley}, author={Meier,
Armin and Badalov, Sabuhi and Biktagirov, Timur and Schmidt, Wolf Gero and Wilhelm,
René}, year={2023}, pages={e202203541} }'
chicago: 'Meier, Armin, Sabuhi Badalov, Timur Biktagirov, Wolf Gero Schmidt, and
René Wilhelm. “Diquat Based Dyes: A New Class of Photoredox Catalysts and Their
Use in Aerobic Thiocyanation.” Chemistry – A European Journal 29, no. 22
(2023): e202203541. https://doi.org/10.1002/chem.202203541.'
ieee: 'A. Meier, S. Badalov, T. Biktagirov, W. G. Schmidt, and R. Wilhelm, “Diquat
Based Dyes: A New Class of Photoredox Catalysts and Their Use in Aerobic Thiocyanation,”
Chemistry – A European Journal, vol. 29, no. 22, p. e202203541, 2023, doi:
10.1002/chem.202203541.'
mla: 'Meier, Armin, et al. “Diquat Based Dyes: A New Class of Photoredox Catalysts
and Their Use in Aerobic Thiocyanation.” Chemistry – A European Journal,
vol. 29, no. 22, Wiley, 2023, p. e202203541, doi:10.1002/chem.202203541.'
short: A. Meier, S. Badalov, T. Biktagirov, W.G. Schmidt, R. Wilhelm, Chemistry
– A European Journal 29 (2023) e202203541.
date_created: 2023-04-16T18:14:24Z
date_updated: 2023-06-26T02:29:15Z
department:
- _id: '35'
- _id: '15'
- _id: '170'
- _id: '295'
- _id: '230'
doi: 10.1002/chem.202203541
extern: '1'
issue: '22'
keyword:
- General Chemistry
- Catalysis
- Organic Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202203541
oa: '1'
page: ' e202203541'
project:
- _id: '52'
name: 'PC2: Computing Resources Provided by the Paderborn Center for Parallel Computing'
publication: Chemistry – A European Journal
publication_identifier:
issn:
- 0947-6539
- 1521-3765
publication_status: published
publisher: Wiley
related_material:
link:
- relation: supplementary_material
url: https://chemistry-europe.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Fchem.202203541&file=chem202203541-sup-0001-misc_information.pdf
status: public
title: 'Diquat Based Dyes: A New Class of Photoredox Catalysts and Their Use in Aerobic
Thiocyanation'
type: journal_article
user_id: '78800'
volume: ' 29'
year: '2023'
...
---
_id: '45828'
abstract:
- lang: eng
text: This article presents the potential-dependent adsorption of two proteins,
bovine serum albumin (BSA) and lysozyme (LYZ), on Ti6Al4V alloy at pH 7.4 and
37 °C. The adsorption process was studied on an electropolished alloy under cathodic
and anodic overpotentials, compared to the open circuit potential (OCP). To analyze
the adsorption process, various complementary interface analytical techniques
were employed, including PM-IRRAS (polarization-modulation infrared reflection-absorption
spectroscopy), AFM (atomic force microscopy), XPS (X-ray photoelectron spectroscopy),
and E-QCM (electrochemical quartz crystal microbalance) measurements. The polarization
experiments were conducted within a potential range where charging of the electric
double layer dominates, and Faradaic currents can be disregarded. The findings
highlight the significant influence of the interfacial charge distribution on
the adsorption of BSA and LYZ onto the alloy surface. Furthermore, electrochemical
analysis of the protein layers formed under applied overpotentials demonstrated
improved corrosion protection properties. These studies provide valuable insights
into protein adsorption on titanium alloys under physiological conditions, characterized
by varying potentials of the passive alloy.
author:
- first_name: Belma
full_name: Duderija, Belma
id: '54863'
last_name: Duderija
- first_name: Alejandro
full_name: González-Orive, Alejandro
last_name: González-Orive
- first_name: Christoph
full_name: Ebbert, Christoph
id: '7266'
last_name: Ebbert
- first_name: Vanessa
full_name: Neßlinger, Vanessa
last_name: Neßlinger
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
citation:
ama: Duderija B, González-Orive A, Ebbert C, Neßlinger V, Keller A, Grundmeier G.
Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy.
Molecules. 2023;28(13):5109. doi:10.3390/molecules28135109
apa: Duderija, B., González-Orive, A., Ebbert, C., Neßlinger, V., Keller, A., &
Grundmeier, G. (2023). Electrode Potential-Dependent Studies of Protein Adsorption
on Ti6Al4V Alloy. Molecules, 28(13), 5109. https://doi.org/10.3390/molecules28135109
bibtex: '@article{Duderija_González-Orive_Ebbert_Neßlinger_Keller_Grundmeier_2023,
title={Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
Alloy}, volume={28}, DOI={10.3390/molecules28135109},
number={13}, journal={Molecules}, publisher={MDPI AG}, author={Duderija, Belma
and González-Orive, Alejandro and Ebbert, Christoph and Neßlinger, Vanessa and
Keller, Adrian and Grundmeier, Guido}, year={2023}, pages={5109} }'
chicago: 'Duderija, Belma, Alejandro González-Orive, Christoph Ebbert, Vanessa Neßlinger,
Adrian Keller, and Guido Grundmeier. “Electrode Potential-Dependent Studies of
Protein Adsorption on Ti6Al4V Alloy.” Molecules 28, no. 13 (2023): 5109.
https://doi.org/10.3390/molecules28135109.'
ieee: 'B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, and G.
Grundmeier, “Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
Alloy,” Molecules, vol. 28, no. 13, p. 5109, 2023, doi: 10.3390/molecules28135109.'
mla: Duderija, Belma, et al. “Electrode Potential-Dependent Studies of Protein Adsorption
on Ti6Al4V Alloy.” Molecules, vol. 28, no. 13, MDPI AG, 2023, p. 5109,
doi:10.3390/molecules28135109.
short: B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, G. Grundmeier,
Molecules 28 (2023) 5109.
date_created: 2023-07-03T08:06:28Z
date_updated: 2023-07-03T08:07:55Z
department:
- _id: '302'
doi: 10.3390/molecules28135109
intvolume: ' 28'
issue: '13'
keyword:
- Chemistry (miscellaneous)
- Analytical Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Molecular Medicine
- Drug Discovery
- Pharmaceutical Science
language:
- iso: eng
page: '5109'
publication: Molecules
publication_identifier:
issn:
- 1420-3049
publication_status: published
publisher: MDPI AG
status: public
title: Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy
type: journal_article
user_id: '48864'
volume: 28
year: '2023'
...
---
_id: '46542'
abstract:
- lang: eng
text: Multiprotein adsorption from complex body fluids represents a highly
important and complicated phenomenon in medicine. In this work, multiprotein adsorption
from diluted human serum at gold and oxidized iron surfaces is investigated at
different serum concentrations and pH values. Adsorption-induced changes in surface
topography and the total amount of adsorbed proteins are quantified by atomic
force microscopy (AFM) and polarization-modulation infrared reflection absorption
spectroscopy (PM-IRRAS), respectively. For both surfaces, stronger protein adsorption
is observed at pH 6 compared to pH 7 and pH 8. PM-IRRAS furthermore provides some
qualitative insights into the pH-dependent alterations in the composition of the
adsorbed multiprotein films. Changes in the amide II/amide I band area ratio and
in particular side-chain IR absorption suggest that the increased adsorption at
pH 6 is accompanied by a change in protein film composition. Presumably, this
is mostly driven by the adsorption of human serum albumin, which at pH 6 adsorbs
more readily and thereby replaces other proteins with lower surface affinities
in the resulting multiprotein film.
article_number: '6060'
author:
- first_name: Jingyuan
full_name: Huang, Jingyuan
last_name: Huang
- first_name: Yunshu
full_name: Qiu, Yunshu
last_name: Qiu
- first_name: Felix
full_name: Lücke, Felix
last_name: Lücke
- first_name: Jiangling
full_name: Su, Jiangling
last_name: Su
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Huang J, Qiu Y, Lücke F, Su J, Grundmeier G, Keller A. Multiprotein Adsorption
from Human Serum at Gold and Oxidized Iron Surfaces Studied by Atomic Force Microscopy
and Polarization-Modulation Infrared Reflection Absorption Spectroscopy. Molecules.
2023;28(16). doi:10.3390/molecules28166060
apa: Huang, J., Qiu, Y., Lücke, F., Su, J., Grundmeier, G., & Keller, A. (2023).
Multiprotein Adsorption from Human Serum at Gold and Oxidized Iron Surfaces Studied
by Atomic Force Microscopy and Polarization-Modulation Infrared Reflection Absorption
Spectroscopy. Molecules, 28(16), Article 6060. https://doi.org/10.3390/molecules28166060
bibtex: '@article{Huang_Qiu_Lücke_Su_Grundmeier_Keller_2023, title={Multiprotein
Adsorption from Human Serum at Gold and Oxidized Iron Surfaces Studied by Atomic
Force Microscopy and Polarization-Modulation Infrared Reflection Absorption Spectroscopy},
volume={28}, DOI={10.3390/molecules28166060},
number={166060}, journal={Molecules}, publisher={MDPI AG}, author={Huang, Jingyuan
and Qiu, Yunshu and Lücke, Felix and Su, Jiangling and Grundmeier, Guido and Keller,
Adrian}, year={2023} }'
chicago: Huang, Jingyuan, Yunshu Qiu, Felix Lücke, Jiangling Su, Guido Grundmeier,
and Adrian Keller. “Multiprotein Adsorption from Human Serum at Gold and Oxidized
Iron Surfaces Studied by Atomic Force Microscopy and Polarization-Modulation Infrared
Reflection Absorption Spectroscopy.” Molecules 28, no. 16 (2023). https://doi.org/10.3390/molecules28166060.
ieee: 'J. Huang, Y. Qiu, F. Lücke, J. Su, G. Grundmeier, and A. Keller, “Multiprotein
Adsorption from Human Serum at Gold and Oxidized Iron Surfaces Studied by Atomic
Force Microscopy and Polarization-Modulation Infrared Reflection Absorption Spectroscopy,”
Molecules, vol. 28, no. 16, Art. no. 6060, 2023, doi: 10.3390/molecules28166060.'
mla: Huang, Jingyuan, et al. “Multiprotein Adsorption from Human Serum at Gold and
Oxidized Iron Surfaces Studied by Atomic Force Microscopy and Polarization-Modulation
Infrared Reflection Absorption Spectroscopy.” Molecules, vol. 28, no. 16,
6060, MDPI AG, 2023, doi:10.3390/molecules28166060.
short: J. Huang, Y. Qiu, F. Lücke, J. Su, G. Grundmeier, A. Keller, Molecules 28
(2023).
date_created: 2023-08-16T10:51:48Z
date_updated: 2023-08-16T10:53:08Z
department:
- _id: '302'
doi: 10.3390/molecules28166060
intvolume: ' 28'
issue: '16'
keyword:
- Chemistry (miscellaneous)
- Analytical Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Molecular Medicine
- Drug Discovery
- Pharmaceutical Science
language:
- iso: eng
publication: Molecules
publication_identifier:
issn:
- 1420-3049
publication_status: published
publisher: MDPI AG
status: public
title: Multiprotein Adsorption from Human Serum at Gold and Oxidized Iron Surfaces
Studied by Atomic Force Microscopy and Polarization-Modulation Infrared Reflection
Absorption Spectroscopy
type: journal_article
user_id: '48864'
volume: 28
year: '2023'
...
---
_id: '46543'
abstract:
- lang: eng
text: The influence of nanoscale surface topography on protein adsorption
is highly important for numerous applications in medicine and technology. Herein,
ferritin adsorption at flat and nanofaceted, single-crystalline Al2O3 surfaces
is investigated using atomic force microscopy and X-ray photoelectron spectroscopy.
The nanofaceted surfaces are generated by the thermal annealing of Al2O3 wafers
at temperatures above 1000 °C, which leads to the formation of faceted saw-tooth-like
surface topographies with periodicities of about 160 nm and amplitudes of about
15 nm. Ferritin adsorption at these nanofaceted surfaces is notably suppressed
compared to the flat surface at a concentration of 10 mg/mL, which is attributed
to lower adsorption affinities of the newly formed facets. Consequently, adsorption
is restricted mostly to the pattern grooves, where the proteins can maximize their
contact area with the surface. However, this effect depends on the protein concentration,
with an inverse trend being observed at 30 mg/mL. Furthermore, different ferritin
adsorption behavior is observed at topographically similar nanofacet patterns
fabricated at different annealing temperatures and attributed to different step
and kink densities. These results demonstrate that while protein adsorption at
solid surfaces can be notably affected by nanofacet patterns, fine-tuning protein
adsorption in this way requires the precise control of facet properties.
article_number: '12808'
author:
- first_name: Bhanu K.
full_name: Pothineni, Bhanu K.
last_name: Pothineni
- first_name: Sabrina
full_name: Kollmann, Sabrina
last_name: Kollmann
- first_name: Xinyang
full_name: Li, Xinyang
last_name: Li
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Denise J.
full_name: Erb, Denise J.
last_name: Erb
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Pothineni BK, Kollmann S, Li X, Grundmeier G, Erb DJ, Keller A. Adsorption
of Ferritin at Nanofaceted Al2O3 Surfaces. International Journal of Molecular
Sciences. 2023;24(16). doi:10.3390/ijms241612808
apa: Pothineni, B. K., Kollmann, S., Li, X., Grundmeier, G., Erb, D. J., & Keller,
A. (2023). Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces. International
Journal of Molecular Sciences, 24(16), Article 12808. https://doi.org/10.3390/ijms241612808
bibtex: '@article{Pothineni_Kollmann_Li_Grundmeier_Erb_Keller_2023, title={Adsorption
of Ferritin at Nanofaceted Al2O3 Surfaces}, volume={24}, DOI={10.3390/ijms241612808},
number={1612808}, journal={International Journal of Molecular Sciences}, publisher={MDPI
AG}, author={Pothineni, Bhanu K. and Kollmann, Sabrina and Li, Xinyang and Grundmeier,
Guido and Erb, Denise J. and Keller, Adrian}, year={2023} }'
chicago: Pothineni, Bhanu K., Sabrina Kollmann, Xinyang Li, Guido Grundmeier, Denise
J. Erb, and Adrian Keller. “Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces.”
International Journal of Molecular Sciences 24, no. 16 (2023). https://doi.org/10.3390/ijms241612808.
ieee: 'B. K. Pothineni, S. Kollmann, X. Li, G. Grundmeier, D. J. Erb, and A. Keller,
“Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces,” International Journal
of Molecular Sciences, vol. 24, no. 16, Art. no. 12808, 2023, doi: 10.3390/ijms241612808.'
mla: Pothineni, Bhanu K., et al. “Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces.”
International Journal of Molecular Sciences, vol. 24, no. 16, 12808, MDPI
AG, 2023, doi:10.3390/ijms241612808.
short: B.K. Pothineni, S. Kollmann, X. Li, G. Grundmeier, D.J. Erb, A. Keller, International
Journal of Molecular Sciences 24 (2023).
date_created: 2023-08-16T10:52:25Z
date_updated: 2023-08-16T10:53:00Z
department:
- _id: '302'
doi: 10.3390/ijms241612808
intvolume: ' 24'
issue: '16'
keyword:
- Inorganic Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Computer Science Applications
- Spectroscopy
- Molecular Biology
- General Medicine
- Catalysis
language:
- iso: eng
publication: International Journal of Molecular Sciences
publication_identifier:
issn:
- 1422-0067
publication_status: published
publisher: MDPI AG
status: public
title: Adsorption of Ferritin at Nanofaceted Al2O3 Surfaces
type: journal_article
user_id: '48864'
volume: 24
year: '2023'
...
---
_id: '30209'
abstract:
- lang: eng
text: DNA origami technology enables the folding of DNA strands into complex
nanoscale shapes whose properties and interactions with molecular species often
deviate significantly from that of genomic DNA. Here, we investigate the salting-out
of different DNA origami shapes by the kosmotropic salt ammonium sulfate that
is routinely employed in protein precipitation. We find that centrifugation in
the presence of 3 M ammonium sulfate results in notable precipitation of DNA origami
nanostructures but not of double-stranded genomic DNA. The precipitated DNA origami
nanostructures can be resuspended in ammonium sulfate-free buffer without apparent
formation of aggregates or loss of structural integrity. Even though quasi-1D
six-helix bundle DNA origami are slightly less susceptible toward salting-out
than more compact DNA origami triangles and 24-helix bundles, precipitation and
recovery yields appear to be mostly independent of DNA origami shape and superstructure.
Exploiting the specificity of ammonium sulfate salting-out for DNA origami nanostructures,
we further apply this method to separate DNA origami triangles from genomic DNA
fragments in a complex mixture. Our results thus demonstrate the possibility of
concentrating and purifying DNA origami nanostructures by ammonium sulfate-induced
salting-out.
author:
- first_name: Marcel
full_name: Hanke, Marcel
last_name: Hanke
- first_name: Niklas
full_name: Hansen, Niklas
last_name: Hansen
- first_name: Ruiping
full_name: Chen, Ruiping
last_name: Chen
- first_name: Guido
full_name: Grundmeier, Guido
last_name: Grundmeier
- first_name: Karim
full_name: Fahmy, Karim
last_name: Fahmy
- first_name: Adrian
full_name: Keller, Adrian
last_name: Keller
citation:
ama: Hanke M, Hansen N, Chen R, Grundmeier G, Fahmy K, Keller A. Salting-Out of
DNA Origami Nanostructures by Ammonium Sulfate. International Journal of Molecular
Sciences. 2022;23(5):2817. doi:10.3390/ijms23052817
apa: Hanke, M., Hansen, N., Chen, R., Grundmeier, G., Fahmy, K., & Keller, A.
(2022). Salting-Out of DNA Origami Nanostructures by Ammonium Sulfate. International
Journal of Molecular Sciences, 23(5), 2817. https://doi.org/10.3390/ijms23052817
bibtex: '@article{Hanke_Hansen_Chen_Grundmeier_Fahmy_Keller_2022, title={Salting-Out
of DNA Origami Nanostructures by Ammonium Sulfate}, volume={23}, DOI={10.3390/ijms23052817},
number={5}, journal={International Journal of Molecular Sciences}, publisher={MDPI
AG}, author={Hanke, Marcel and Hansen, Niklas and Chen, Ruiping and Grundmeier,
Guido and Fahmy, Karim and Keller, Adrian}, year={2022}, pages={2817} }'
chicago: 'Hanke, Marcel, Niklas Hansen, Ruiping Chen, Guido Grundmeier, Karim Fahmy,
and Adrian Keller. “Salting-Out of DNA Origami Nanostructures by Ammonium Sulfate.”
International Journal of Molecular Sciences 23, no. 5 (2022): 2817. https://doi.org/10.3390/ijms23052817.'
ieee: 'M. Hanke, N. Hansen, R. Chen, G. Grundmeier, K. Fahmy, and A. Keller, “Salting-Out
of DNA Origami Nanostructures by Ammonium Sulfate,” International Journal of
Molecular Sciences, vol. 23, no. 5, p. 2817, 2022, doi: 10.3390/ijms23052817.'
mla: Hanke, Marcel, et al. “Salting-Out of DNA Origami Nanostructures by Ammonium
Sulfate.” International Journal of Molecular Sciences, vol. 23, no. 5,
MDPI AG, 2022, p. 2817, doi:10.3390/ijms23052817.
short: M. Hanke, N. Hansen, R. Chen, G. Grundmeier, K. Fahmy, A. Keller, International
Journal of Molecular Sciences 23 (2022) 2817.
date_created: 2022-03-07T07:28:02Z
date_updated: 2022-03-07T07:29:27Z
department:
- _id: '302'
doi: 10.3390/ijms23052817
intvolume: ' 23'
issue: '5'
keyword:
- Inorganic Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Computer Science Applications
- Spectroscopy
- Molecular Biology
- General Medicine
- Catalysis
language:
- iso: eng
page: '2817'
publication: International Journal of Molecular Sciences
publication_identifier:
issn:
- 1422-0067
publication_status: published
publisher: MDPI AG
status: public
title: Salting-Out of DNA Origami Nanostructures by Ammonium Sulfate
type: journal_article
user_id: '48864'
volume: 23
year: '2022'
...