[{"title":"Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides","doi":"10.1002/adsc.70059","date_updated":"2025-11-10T08:44:04Z","publisher":"Wiley","author":[{"first_name":"Viktorija","last_name":"Medvaric","full_name":"Medvaric, Viktorija","id":"92677"},{"id":"53339","full_name":"Paradies, Jan","orcid":"0000-0002-3698-668X","last_name":"Paradies","first_name":"Jan"},{"first_name":"Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","full_name":"Werner, Thomas","id":"89271"}],"date_created":"2025-09-17T15:16:49Z","year":"2025","citation":{"chicago":"Medvaric, Viktorija, Jan Paradies, and Thomas Werner. “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides.” <i>Advanced Synthesis and Catalysis</i>, 2025. <a href=\"https://doi.org/10.1002/adsc.70059\">https://doi.org/10.1002/adsc.70059</a>.","ieee":"V. Medvaric, J. Paradies, and T. Werner, “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides,” <i>Advanced Synthesis and Catalysis</i>, Art. no. 202500394, 2025, doi: <a href=\"https://doi.org/10.1002/adsc.70059\">10.1002/adsc.70059</a>.","ama":"Medvaric V, Paradies J, Werner T. Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides. <i>Advanced Synthesis and Catalysis</i>. Published online 2025. doi:<a href=\"https://doi.org/10.1002/adsc.70059\">10.1002/adsc.70059</a>","mla":"Medvaric, Viktorija, et al. “Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides.” <i>Advanced Synthesis and Catalysis</i>, 202500394, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/adsc.70059\">10.1002/adsc.70059</a>.","short":"V. Medvaric, J. Paradies, T. Werner, Advanced Synthesis and Catalysis (2025).","bibtex":"@article{Medvaric_Paradies_Werner_2025, title={Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides}, DOI={<a href=\"https://doi.org/10.1002/adsc.70059\">10.1002/adsc.70059</a>}, number={202500394}, journal={Advanced Synthesis and Catalysis}, publisher={Wiley}, author={Medvaric, Viktorija and Paradies, Jan and Werner, Thomas}, year={2025} }","apa":"Medvaric, V., Paradies, J., &#38; Werner, T. (2025). Synthesis of Amidines Via P(III)/P(V)=O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides. <i>Advanced Synthesis and Catalysis</i>, Article 202500394. <a href=\"https://doi.org/10.1002/adsc.70059\">https://doi.org/10.1002/adsc.70059</a>"},"publication_status":"published","publication_identifier":{"issn":["1615-4150","1615-4169"]},"article_number":"202500394","keyword":["T2","T","CSSD"],"language":[{"iso":"eng"}],"_id":"61335","user_id":"89271","department":[{"_id":"2"},{"_id":"389"}],"abstract":[{"lang":"eng","text":"<jats:p>Amidines are a ubiquitous class of bioactive compounds found in a wide variety of natural products; thus, efficient strategies for their preparation are in great demand. Herein, a novel protocol is reported for the synthesis of amidines based on P<jats:sup>III</jats:sup>/P<jats:sup>V</jats:sup>O redox catalysis. This two‐step, one‐pot approach involves the activation of amides via P<jats:sup>III</jats:sup>/P<jats:sup>V</jats:sup>O catalyzed in situ formation of imidoyl chloride intermediates which are directly converted upon reaction with amines into the corresponding amidines. Instead of traditionally used toxic and corrosive chloride sources, hexachloroacetone (HCA) is successfully employed as a halide source. The reaction proceeds with low catalyst loading (2 mol%) in BuOAc as the solvent. Under the optimized conditions, 20 amidines are prepared in yields up to 99%. A feasible mechanism is proposed based on experimental results. The synthetic potential of this method is evaluated in the preparation of the tyrosine kinase inhibitor (TKI) Erlotinib.</jats:p>"}],"status":"public","type":"journal_article","publication":"Advanced Synthesis and Catalysis"},{"title":"Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance","doi":"10.1021/jacs.5c06190","date_updated":"2025-11-10T08:43:50Z","publisher":"American Chemical Society (ACS)","author":[{"first_name":"Rundong","last_name":"Zhou","full_name":"Zhou, Rundong"},{"first_name":"Viktorija","last_name":"Medvaric","id":"92677","full_name":"Medvaric, Viktorija"},{"first_name":"Thomas","full_name":"Werner, Thomas","id":"89271","orcid":"https://orcid.org/0000-0001-9025-3244","last_name":"Werner"},{"first_name":"Jan","id":"53339","full_name":"Paradies, Jan","last_name":"Paradies","orcid":"0000-0002-3698-668X"}],"date_created":"2025-09-17T15:18:11Z","year":"2025","citation":{"chicago":"Zhou, Rundong, Viktorija Medvaric, Thomas Werner, and Jan Paradies. “Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance.” <i>Journal of the American Chemical Society</i>, 2025. <a href=\"https://doi.org/10.1021/jacs.5c06190\">https://doi.org/10.1021/jacs.5c06190</a>.","ieee":"R. Zhou, V. Medvaric, T. Werner, and J. Paradies, “Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance,” <i>Journal of the American Chemical Society</i>, Art. no. jacs. 5c06190, 2025, doi: <a href=\"https://doi.org/10.1021/jacs.5c06190\">10.1021/jacs.5c06190</a>.","ama":"Zhou R, Medvaric V, Werner T, Paradies J. Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance. <i>Journal of the American Chemical Society</i>. Published online 2025. doi:<a href=\"https://doi.org/10.1021/jacs.5c06190\">10.1021/jacs.5c06190</a>","apa":"Zhou, R., Medvaric, V., Werner, T., &#38; Paradies, J. (2025). Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance. <i>Journal of the American Chemical Society</i>, Article jacs. 5c06190. <a href=\"https://doi.org/10.1021/jacs.5c06190\">https://doi.org/10.1021/jacs.5c06190</a>","mla":"Zhou, Rundong, et al. “Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance.” <i>Journal of the American Chemical Society</i>, jacs. 5c06190, American Chemical Society (ACS), 2025, doi:<a href=\"https://doi.org/10.1021/jacs.5c06190\">10.1021/jacs.5c06190</a>.","bibtex":"@article{Zhou_Medvaric_Werner_Paradies_2025, title={Metal-Free Reduction of Nitrous Oxide via P<sup>III</sup>/P<sup>V</sup>═O Cycling: Mechanistic Insights and Catalytic Performance}, DOI={<a href=\"https://doi.org/10.1021/jacs.5c06190\">10.1021/jacs.5c06190</a>}, number={jacs. 5c06190}, journal={Journal of the American Chemical Society}, publisher={American Chemical Society (ACS)}, author={Zhou, Rundong and Medvaric, Viktorija and Werner, Thomas and Paradies, Jan}, year={2025} }","short":"R. Zhou, V. Medvaric, T. Werner, J. Paradies, Journal of the American Chemical Society (2025)."},"publication_identifier":{"issn":["0002-7863","1520-5126"]},"publication_status":"published","keyword":["T2","CSSD"],"article_number":"jacs.5c06190","language":[{"iso":"eng"}],"_id":"61336","department":[{"_id":"2"},{"_id":"389"}],"user_id":"89271","status":"public","publication":"Journal of the American Chemical Society","type":"journal_article"},{"publication":"Green Chemistry","type":"journal_article","abstract":[{"text":"<jats:p>The selective <jats:italic>N</jats:italic>-formylation and <jats:italic>N</jats:italic>-methylation of amines with carbon dioxide (CO<jats:sub>2</jats:sub>) catalyzed by methyltriphenylphosphonium methylcarbonate and tuned by polymethylhydrosiloxane or trimethoxysilane as reducing agents is reported.</jats:p>","lang":"eng"}],"status":"public","_id":"62090","department":[{"_id":"35"},{"_id":"2"}],"user_id":"89271","keyword":["T1","T2","CSSD"],"language":[{"iso":"eng"}],"publication_identifier":{"issn":["1463-9262","1463-9270"]},"publication_status":"published","issue":"1","year":"2024","intvolume":"        26","page":"439-447","citation":{"apa":"Ren, C., Terazzi, C., &#38; Werner, T. (2024). Tuneable reduction of CO<sub>2</sub> – organocatalyzed selective formylation and methylation of amines. <i>Green Chemistry</i>, <i>26</i>(1), 439–447. <a href=\"https://doi.org/10.1039/d3gc03993e\">https://doi.org/10.1039/d3gc03993e</a>","short":"C. Ren, C. Terazzi, T. Werner, Green Chemistry 26 (2024) 439–447.","bibtex":"@article{Ren_Terazzi_Werner_2024, title={Tuneable reduction of CO<sub>2</sub> – organocatalyzed selective formylation and methylation of amines}, volume={26}, DOI={<a href=\"https://doi.org/10.1039/d3gc03993e\">10.1039/d3gc03993e</a>}, number={1}, journal={Green Chemistry}, publisher={Royal Society of Chemistry (RSC)}, author={Ren, Changyue and Terazzi, Constanza and Werner, Thomas}, year={2024}, pages={439–447} }","mla":"Ren, Changyue, et al. “Tuneable Reduction of CO<sub>2</sub> – Organocatalyzed Selective Formylation and Methylation of Amines.” <i>Green Chemistry</i>, vol. 26, no. 1, Royal Society of Chemistry (RSC), 2024, pp. 439–47, doi:<a href=\"https://doi.org/10.1039/d3gc03993e\">10.1039/d3gc03993e</a>.","ieee":"C. Ren, C. Terazzi, and T. Werner, “Tuneable reduction of CO<sub>2</sub> – organocatalyzed selective formylation and methylation of amines,” <i>Green Chemistry</i>, vol. 26, no. 1, pp. 439–447, 2024, doi: <a href=\"https://doi.org/10.1039/d3gc03993e\">10.1039/d3gc03993e</a>.","chicago":"Ren, Changyue, Constanza Terazzi, and Thomas Werner. “Tuneable Reduction of CO<sub>2</sub> – Organocatalyzed Selective Formylation and Methylation of Amines.” <i>Green Chemistry</i> 26, no. 1 (2024): 439–47. <a href=\"https://doi.org/10.1039/d3gc03993e\">https://doi.org/10.1039/d3gc03993e</a>.","ama":"Ren C, Terazzi C, Werner T. Tuneable reduction of CO<sub>2</sub> – organocatalyzed selective formylation and methylation of amines. <i>Green Chemistry</i>. 2024;26(1):439-447. doi:<a href=\"https://doi.org/10.1039/d3gc03993e\">10.1039/d3gc03993e</a>"},"publisher":"Royal Society of Chemistry (RSC)","date_updated":"2025-11-10T08:44:44Z","volume":26,"date_created":"2025-11-05T15:16:32Z","author":[{"full_name":"Ren, Changyue","last_name":"Ren","first_name":"Changyue"},{"full_name":"Terazzi, Constanza","last_name":"Terazzi","first_name":"Constanza"},{"first_name":"Thomas","id":"89271","full_name":"Werner, Thomas","orcid":"0000-0001-9025-3244","last_name":"Werner"}],"title":"Tuneable reduction of CO<sub>2</sub> – organocatalyzed selective formylation and methylation of amines","doi":"10.1039/d3gc03993e"},{"date_updated":"2025-11-10T08:45:58Z","publisher":"American Chemical Society (ACS)","author":[{"full_name":"Ren, Changyue","last_name":"Ren","first_name":"Changyue"},{"first_name":"Anke","full_name":"Spannenberg, Anke","last_name":"Spannenberg"},{"first_name":"Thomas","orcid":"0000-0001-9025-3244","last_name":"Werner","id":"89271","full_name":"Werner, Thomas"}],"date_created":"2025-11-05T15:17:55Z","volume":12,"title":"Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>","doi":"10.1021/acssuschemeng.4c03464","publication_status":"published","publication_identifier":{"issn":["2168-0485","2168-0485"]},"issue":"29","year":"2024","citation":{"short":"C. Ren, A. Spannenberg, T. Werner, ACS Sustainable Chemistry &#38;amp; Engineering 12 (2024) 10969–10977.","mla":"Ren, Changyue, et al. “Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>.” <i>ACS Sustainable Chemistry &#38;amp; Engineering</i>, vol. 12, no. 29, American Chemical Society (ACS), 2024, pp. 10969–77, doi:<a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">10.1021/acssuschemeng.4c03464</a>.","bibtex":"@article{Ren_Spannenberg_Werner_2024, title={Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>}, volume={12}, DOI={<a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">10.1021/acssuschemeng.4c03464</a>}, number={29}, journal={ACS Sustainable Chemistry &#38;amp; Engineering}, publisher={American Chemical Society (ACS)}, author={Ren, Changyue and Spannenberg, Anke and Werner, Thomas}, year={2024}, pages={10969–10977} }","apa":"Ren, C., Spannenberg, A., &#38; Werner, T. (2024). Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>. <i>ACS Sustainable Chemistry &#38;amp; Engineering</i>, <i>12</i>(29), 10969–10977. <a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">https://doi.org/10.1021/acssuschemeng.4c03464</a>","ieee":"C. Ren, A. Spannenberg, and T. Werner, “Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>,” <i>ACS Sustainable Chemistry &#38;amp; Engineering</i>, vol. 12, no. 29, pp. 10969–10977, 2024, doi: <a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">10.1021/acssuschemeng.4c03464</a>.","chicago":"Ren, Changyue, Anke Spannenberg, and Thomas Werner. “Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>.” <i>ACS Sustainable Chemistry &#38;amp; Engineering</i> 12, no. 29 (2024): 10969–77. <a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">https://doi.org/10.1021/acssuschemeng.4c03464</a>.","ama":"Ren C, Spannenberg A, Werner T. Phosphonium-Salt-Catalyzed <i>N</i>-Methylation and <i>N</i>-Formylation of Amines with CO<sub>2</sub>. <i>ACS Sustainable Chemistry &#38;amp; Engineering</i>. 2024;12(29):10969-10977. doi:<a href=\"https://doi.org/10.1021/acssuschemeng.4c03464\">10.1021/acssuschemeng.4c03464</a>"},"intvolume":"        12","page":"10969-10977","_id":"62091","user_id":"89271","department":[{"_id":"35"},{"_id":"2"}],"keyword":["T1","T2","CSSD"],"language":[{"iso":"eng"}],"type":"journal_article","publication":"ACS Sustainable Chemistry &amp; Engineering","status":"public"},{"department":[{"_id":"35"},{"_id":"2"}],"user_id":"89271","_id":"62088","type":"journal_article","status":"public","volume":89,"author":[{"last_name":"Tönjes","full_name":"Tönjes, Jan","first_name":"Jan"},{"first_name":"Viktorija","last_name":"Medvarić","full_name":"Medvarić, Viktorija"},{"first_name":"Thomas","last_name":"Werner","full_name":"Werner, Thomas"}],"date_updated":"2025-11-10T08:45:17Z","doi":"10.1021/acs.joc.4c00985","publication_identifier":{"issn":["0022-3263","1520-6904"]},"publication_status":"published","intvolume":"        89","page":"10729-10735","citation":{"apa":"Tönjes, J., Medvarić, V., &#38; Werner, T. (2024). Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis. <i>The Journal of Organic Chemistry</i>, <i>89</i>(15), 10729–10735. <a href=\"https://doi.org/10.1021/acs.joc.4c00985\">https://doi.org/10.1021/acs.joc.4c00985</a>","bibtex":"@article{Tönjes_Medvarić_Werner_2024, title={Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis}, volume={89}, DOI={<a href=\"https://doi.org/10.1021/acs.joc.4c00985\">10.1021/acs.joc.4c00985</a>}, number={15}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Tönjes, Jan and Medvarić, Viktorija and Werner, Thomas}, year={2024}, pages={10729–10735} }","mla":"Tönjes, Jan, et al. “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis.” <i>The Journal of Organic Chemistry</i>, vol. 89, no. 15, American Chemical Society (ACS), 2024, pp. 10729–35, doi:<a href=\"https://doi.org/10.1021/acs.joc.4c00985\">10.1021/acs.joc.4c00985</a>.","short":"J. Tönjes, V. Medvarić, T. Werner, The Journal of Organic Chemistry 89 (2024) 10729–10735.","ama":"Tönjes J, Medvarić V, Werner T. Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis. <i>The Journal of Organic Chemistry</i>. 2024;89(15):10729-10735. doi:<a href=\"https://doi.org/10.1021/acs.joc.4c00985\">10.1021/acs.joc.4c00985</a>","ieee":"J. Tönjes, V. Medvarić, and T. Werner, “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis,” <i>The Journal of Organic Chemistry</i>, vol. 89, no. 15, pp. 10729–10735, 2024, doi: <a href=\"https://doi.org/10.1021/acs.joc.4c00985\">10.1021/acs.joc.4c00985</a>.","chicago":"Tönjes, Jan, Viktorija Medvarić, and Thomas Werner. “Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis.” <i>The Journal of Organic Chemistry</i> 89, no. 15 (2024): 10729–35. <a href=\"https://doi.org/10.1021/acs.joc.4c00985\">https://doi.org/10.1021/acs.joc.4c00985</a>."},"language":[{"iso":"eng"}],"keyword":["T2","CSSD"],"publication":"The Journal of Organic Chemistry","date_created":"2025-11-05T15:12:46Z","publisher":"American Chemical Society (ACS)","title":"Synthesis of Trisubstituted Furans from Activated Alkenes by P(III)/P(V) Redox Cycling Catalysis","issue":"15","year":"2024"},{"type":"journal_article","publication":"Organic Letters","status":"public","user_id":"89271","department":[{"_id":"35"},{"_id":"2"}],"_id":"62095","language":[{"iso":"eng"}],"keyword":["T2","CSSD"],"issue":"51","publication_status":"published","publication_identifier":{"issn":["1523-7060","1523-7052"]},"citation":{"mla":"Tönjes, Jan, et al. “Organocatalytic Stereospecific Appel Reaction.” <i>Organic Letters</i>, vol. 25, no. 51, American Chemical Society (ACS), 2023, pp. 9114–18, doi:<a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">10.1021/acs.orglett.3c03463</a>.","bibtex":"@article{Tönjes_Kell_Werner_2023, title={Organocatalytic Stereospecific Appel Reaction}, volume={25}, DOI={<a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">10.1021/acs.orglett.3c03463</a>}, number={51}, journal={Organic Letters}, publisher={American Chemical Society (ACS)}, author={Tönjes, Jan and Kell, Lukas and Werner, Thomas}, year={2023}, pages={9114–9118} }","short":"J. Tönjes, L. Kell, T. Werner, Organic Letters 25 (2023) 9114–9118.","apa":"Tönjes, J., Kell, L., &#38; Werner, T. (2023). Organocatalytic Stereospecific Appel Reaction. <i>Organic Letters</i>, <i>25</i>(51), 9114–9118. <a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">https://doi.org/10.1021/acs.orglett.3c03463</a>","ama":"Tönjes J, Kell L, Werner T. Organocatalytic Stereospecific Appel Reaction. <i>Organic Letters</i>. 2023;25(51):9114-9118. doi:<a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">10.1021/acs.orglett.3c03463</a>","ieee":"J. Tönjes, L. Kell, and T. Werner, “Organocatalytic Stereospecific Appel Reaction,” <i>Organic Letters</i>, vol. 25, no. 51, pp. 9114–9118, 2023, doi: <a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">10.1021/acs.orglett.3c03463</a>.","chicago":"Tönjes, Jan, Lukas Kell, and Thomas Werner. “Organocatalytic Stereospecific Appel Reaction.” <i>Organic Letters</i> 25, no. 51 (2023): 9114–18. <a href=\"https://doi.org/10.1021/acs.orglett.3c03463\">https://doi.org/10.1021/acs.orglett.3c03463</a>."},"intvolume":"        25","page":"9114-9118","year":"2023","date_created":"2025-11-05T15:22:44Z","author":[{"last_name":"Tönjes","full_name":"Tönjes, Jan","first_name":"Jan"},{"full_name":"Kell, Lukas","last_name":"Kell","first_name":"Lukas"},{"id":"89271","full_name":"Werner, Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","first_name":"Thomas"}],"volume":25,"date_updated":"2025-11-10T08:46:39Z","publisher":"American Chemical Society (ACS)","doi":"10.1021/acs.orglett.3c03463","title":"Organocatalytic Stereospecific Appel Reaction"},{"publication_identifier":{"issn":["2193-5807","2193-5815"]},"publication_status":"published","issue":"9","year":"2022","intvolume":"        11","citation":{"ama":"Ren C, Spannenberg A, Werner T. Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>. <i>Asian Journal of Organic Chemistry</i>. 2022;11(9). doi:<a href=\"https://doi.org/10.1002/ajoc.202200156\">10.1002/ajoc.202200156</a>","chicago":"Ren, Changyue, Anke Spannenberg, and Thomas Werner. “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>.” <i>Asian Journal of Organic Chemistry</i> 11, no. 9 (2022). <a href=\"https://doi.org/10.1002/ajoc.202200156\">https://doi.org/10.1002/ajoc.202200156</a>.","ieee":"C. Ren, A. Spannenberg, and T. Werner, “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>,” <i>Asian Journal of Organic Chemistry</i>, vol. 11, no. 9, 2022, doi: <a href=\"https://doi.org/10.1002/ajoc.202200156\">10.1002/ajoc.202200156</a>.","short":"C. Ren, A. Spannenberg, T. Werner, Asian Journal of Organic Chemistry 11 (2022).","bibtex":"@article{Ren_Spannenberg_Werner_2022, title={Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>}, volume={11}, DOI={<a href=\"https://doi.org/10.1002/ajoc.202200156\">10.1002/ajoc.202200156</a>}, number={9}, journal={Asian Journal of Organic Chemistry}, publisher={Wiley}, author={Ren, Changyue and Spannenberg, Anke and Werner, Thomas}, year={2022} }","mla":"Ren, Changyue, et al. “Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>.” <i>Asian Journal of Organic Chemistry</i>, vol. 11, no. 9, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/ajoc.202200156\">10.1002/ajoc.202200156</a>.","apa":"Ren, C., Spannenberg, A., &#38; Werner, T. (2022). Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>. <i>Asian Journal of Organic Chemistry</i>, <i>11</i>(9). <a href=\"https://doi.org/10.1002/ajoc.202200156\">https://doi.org/10.1002/ajoc.202200156</a>"},"date_updated":"2025-11-10T08:47:20Z","publisher":"Wiley","volume":11,"author":[{"full_name":"Ren, Changyue","last_name":"Ren","first_name":"Changyue"},{"first_name":"Anke","last_name":"Spannenberg","full_name":"Spannenberg, Anke"},{"full_name":"Werner, Thomas","id":"89271","last_name":"Werner","orcid":"0000-0001-9025-3244","first_name":"Thomas"}],"date_created":"2023-01-22T20:19:21Z","title":"Synthesis of Bifunctional Phosphonium Salts Bearing Perfluorinated Side Chains and Their Application in the Synthesis of Cyclic Carbonates from Epoxides and CO            <sub>2</sub>","doi":"10.1002/ajoc.202200156","publication":"Asian Journal of Organic Chemistry","type":"journal_article","status":"public","_id":"37940","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"user_id":"89271","keyword":["T1","T2","CSSD"],"language":[{"iso":"eng"}]},{"_id":"37946","user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"keyword":["T2","T4","CSSD"],"language":[{"iso":"eng"}],"type":"journal_article","publication":"Synthesis","abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title><jats:p>The facile synthesis of highly functionalized building blocks with potential biological activity is of great interest to medicinal chemistry. The benzoxepinone core structures commonly exhibit biological activity. Thus, a short and efficient synthetic route towards benzoxepine containing scaffold, which enables late stage modification was developed. Namely, base-free catalytic Wittig reactions enabled the synthesis of bromobenzoxepinones from readily available starting materials. Subsequent, Suzuki–Miyaura and Stille reactions proved to be suitable methods to access a variety of benzoxepinone diaryl derivatives by late stage modification in only three steps. This three-step reaction sequence is suitable for high throughput applications and gives facile access to highly complex molecular structures, which are suitable for further functionalization. The antiproliferative properties of selected arylbenzoxepinones­ were tested in vitro on monolayer tumor cell line A549. Notably, in this initial screening, these compounds were found to be active in the micromolar range.</jats:p>"}],"status":"public","date_updated":"2025-11-10T08:47:47Z","publisher":"Georg Thieme Verlag KG","author":[{"orcid":"0000-0001-9025-3244","last_name":"Werner","id":"89271","full_name":"Werner, Thomas","first_name":"Thomas"},{"full_name":"Grandane, Aiga","last_name":"Grandane","first_name":"Aiga"},{"first_name":"Linda","last_name":"Pudnika","full_name":"Pudnika, Linda"},{"last_name":"Domraceva","full_name":"Domraceva, Ilona","first_name":"Ilona"},{"last_name":"Zalubovskis","full_name":"Zalubovskis, Raivis","first_name":"Raivis"}],"date_created":"2023-01-22T20:27:34Z","volume":53,"title":"Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones","doi":"10.1055/a-1509-6078","publication_status":"published","publication_identifier":{"issn":["0039-7881","1437-210X"]},"issue":"19","year":"2021","citation":{"ama":"Werner T, Grandane A, Pudnika L, Domraceva I, Zalubovskis R. Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones. <i>Synthesis</i>. 2021;53(19):3545-3554. doi:<a href=\"https://doi.org/10.1055/a-1509-6078\">10.1055/a-1509-6078</a>","chicago":"Werner, Thomas, Aiga Grandane, Linda Pudnika, Ilona Domraceva, and Raivis Zalubovskis. “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones.” <i>Synthesis</i> 53, no. 19 (2021): 3545–54. <a href=\"https://doi.org/10.1055/a-1509-6078\">https://doi.org/10.1055/a-1509-6078</a>.","ieee":"T. Werner, A. Grandane, L. Pudnika, I. Domraceva, and R. Zalubovskis, “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones,” <i>Synthesis</i>, vol. 53, no. 19, pp. 3545–3554, 2021, doi: <a href=\"https://doi.org/10.1055/a-1509-6078\">10.1055/a-1509-6078</a>.","apa":"Werner, T., Grandane, A., Pudnika, L., Domraceva, I., &#38; Zalubovskis, R. (2021). Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones. <i>Synthesis</i>, <i>53</i>(19), 3545–3554. <a href=\"https://doi.org/10.1055/a-1509-6078\">https://doi.org/10.1055/a-1509-6078</a>","short":"T. Werner, A. Grandane, L. Pudnika, I. Domraceva, R. Zalubovskis, Synthesis 53 (2021) 3545–3554.","mla":"Werner, Thomas, et al. “Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones.” <i>Synthesis</i>, vol. 53, no. 19, Georg Thieme Verlag KG, 2021, pp. 3545–54, doi:<a href=\"https://doi.org/10.1055/a-1509-6078\">10.1055/a-1509-6078</a>.","bibtex":"@article{Werner_Grandane_Pudnika_Domraceva_Zalubovskis_2021, title={Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones}, volume={53}, DOI={<a href=\"https://doi.org/10.1055/a-1509-6078\">10.1055/a-1509-6078</a>}, number={19}, journal={Synthesis}, publisher={Georg Thieme Verlag KG}, author={Werner, Thomas and Grandane, Aiga and Pudnika, Linda and Domraceva, Ilona and Zalubovskis, Raivis}, year={2021}, pages={3545–3554} }"},"page":"3545-3554","intvolume":"        53"},{"publisher":"Royal Society of Chemistry (RSC)","date_created":"2023-01-22T20:25:13Z","title":"Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction","issue":"13","year":"2021","keyword":["T2","CSSD"],"language":[{"iso":"eng"}],"publication":"Green Chemistry","abstract":[{"text":"<p>PMHS proved to be a suitable terminal reductant for P(<sc>iii</sc>)/P(<sc>v</sc>) redox cycling with a methyl-substituted phosphetane as catalyst and BuOAc as solvent. The formation of water by silanol condensation was identified as main pathway of siloxane formation.</p>","lang":"eng"}],"date_updated":"2025-11-10T08:48:01Z","volume":23,"author":[{"full_name":"Tönjes, Jan","last_name":"Tönjes","first_name":"Jan"},{"first_name":"Lars","full_name":"Longwitz, Lars","last_name":"Longwitz"},{"id":"89271","full_name":"Werner, Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","first_name":"Thomas"}],"doi":"10.1039/d1gc00953b","publication_identifier":{"issn":["1463-9262","1463-9270"]},"publication_status":"published","intvolume":"        23","page":"4852-4857","citation":{"apa":"Tönjes, J., Longwitz, L., &#38; Werner, T. (2021). Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction. <i>Green Chemistry</i>, <i>23</i>(13), 4852–4857. <a href=\"https://doi.org/10.1039/d1gc00953b\">https://doi.org/10.1039/d1gc00953b</a>","bibtex":"@article{Tönjes_Longwitz_Werner_2021, title={Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction}, volume={23}, DOI={<a href=\"https://doi.org/10.1039/d1gc00953b\">10.1039/d1gc00953b</a>}, number={13}, journal={Green Chemistry}, publisher={Royal Society of Chemistry (RSC)}, author={Tönjes, Jan and Longwitz, Lars and Werner, Thomas}, year={2021}, pages={4852–4857} }","short":"J. Tönjes, L. Longwitz, T. Werner, Green Chemistry 23 (2021) 4852–4857.","mla":"Tönjes, Jan, et al. “Poly(Methylhydrosiloxane) as a Reductant in the Catalytic Base-Free Wittig Reaction.” <i>Green Chemistry</i>, vol. 23, no. 13, Royal Society of Chemistry (RSC), 2021, pp. 4852–57, doi:<a href=\"https://doi.org/10.1039/d1gc00953b\">10.1039/d1gc00953b</a>.","ieee":"J. Tönjes, L. Longwitz, and T. Werner, “Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction,” <i>Green Chemistry</i>, vol. 23, no. 13, pp. 4852–4857, 2021, doi: <a href=\"https://doi.org/10.1039/d1gc00953b\">10.1039/d1gc00953b</a>.","chicago":"Tönjes, Jan, Lars Longwitz, and Thomas Werner. “Poly(Methylhydrosiloxane) as a Reductant in the Catalytic Base-Free Wittig Reaction.” <i>Green Chemistry</i> 23, no. 13 (2021): 4852–57. <a href=\"https://doi.org/10.1039/d1gc00953b\">https://doi.org/10.1039/d1gc00953b</a>.","ama":"Tönjes J, Longwitz L, Werner T. Poly(methylhydrosiloxane) as a reductant in the catalytic base-free Wittig reaction. <i>Green Chemistry</i>. 2021;23(13):4852-4857. doi:<a href=\"https://doi.org/10.1039/d1gc00953b\">10.1039/d1gc00953b</a>"},"_id":"37945","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"user_id":"89271","type":"journal_article","status":"public"},{"_id":"62101","department":[{"_id":"35"},{"_id":"2"}],"user_id":"89271","keyword":["T2","T4"],"language":[{"iso":"eng"}],"publication":"Angewandte Chemie","type":"journal_article","abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title><jats:p>The carbon–carbon double bond of unsaturated carbonyl compounds was readily reduced by using a phosphetane oxide catalyst in the presence of a simple organosilane as the terminal reductant and water as the hydrogen source. Quantitative hydrogenation was observed when 1.0 mol % of a methyl‐substituted phosphetane oxide was employed as the catalyst. The procedure is highly selective towards activated double bonds, tolerating a variety of functional groups that are usually prone to reduction. In total, 25 alkenes and two alkynes were hydrogenated to the corresponding alkanes in excellent yields of up to 99 %. Notably, less active poly(methylhydrosiloxane) could also be utilized as the terminal reductant. Mechanistic investigations revealed the phosphane as the catalyst resting state and a protonation/deprotonation sequence as the crucial step in the catalytic cycle.</jats:p>"}],"status":"public","publisher":"Wiley","date_updated":"2025-11-10T08:11:23Z","volume":132,"author":[{"full_name":"Longwitz, Lars","last_name":"Longwitz","first_name":"Lars"},{"last_name":"Werner","orcid":"0000-0001-9025-3244","id":"89271","full_name":"Werner, Thomas","first_name":"Thomas"}],"date_created":"2025-11-05T15:39:06Z","title":"Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis","doi":"10.1002/ange.201912991","publication_identifier":{"issn":["0044-8249","1521-3757"]},"publication_status":"published","issue":"7","year":"2020","intvolume":"       132","page":"2782-2785","citation":{"ama":"Longwitz L, Werner T. Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis. <i>Angewandte Chemie</i>. 2020;132(7):2782-2785. doi:<a href=\"https://doi.org/10.1002/ange.201912991\">10.1002/ange.201912991</a>","chicago":"Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis.” <i>Angewandte Chemie</i> 132, no. 7 (2020): 2782–85. <a href=\"https://doi.org/10.1002/ange.201912991\">https://doi.org/10.1002/ange.201912991</a>.","ieee":"L. Longwitz and T. Werner, “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis,” <i>Angewandte Chemie</i>, vol. 132, no. 7, pp. 2782–2785, 2020, doi: <a href=\"https://doi.org/10.1002/ange.201912991\">10.1002/ange.201912991</a>.","short":"L. Longwitz, T. Werner, Angewandte Chemie 132 (2020) 2782–2785.","bibtex":"@article{Longwitz_Werner_2020, title={Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis}, volume={132}, DOI={<a href=\"https://doi.org/10.1002/ange.201912991\">10.1002/ange.201912991</a>}, number={7}, journal={Angewandte Chemie}, publisher={Wiley}, author={Longwitz, Lars and Werner, Thomas}, year={2020}, pages={2782–2785} }","mla":"Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis.” <i>Angewandte Chemie</i>, vol. 132, no. 7, Wiley, 2020, pp. 2782–85, doi:<a href=\"https://doi.org/10.1002/ange.201912991\">10.1002/ange.201912991</a>.","apa":"Longwitz, L., &#38; Werner, T. (2020). Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis. <i>Angewandte Chemie</i>, <i>132</i>(7), 2782–2785. <a href=\"https://doi.org/10.1002/ange.201912991\">https://doi.org/10.1002/ange.201912991</a>"}},{"year":"2020","citation":{"short":"L. Longwitz, T. Werner, Angewandte Chemie International Edition 59 (2020) 2760–2763.","bibtex":"@article{Longwitz_Werner_2020, title={Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis}, volume={59}, DOI={<a href=\"https://doi.org/10.1002/anie.201912991\">10.1002/anie.201912991</a>}, number={7}, journal={Angewandte Chemie International Edition}, publisher={Wiley}, author={Longwitz, Lars and Werner, Thomas}, year={2020}, pages={2760–2763} }","mla":"Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis.” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 7, Wiley, 2020, pp. 2760–63, doi:<a href=\"https://doi.org/10.1002/anie.201912991\">10.1002/anie.201912991</a>.","apa":"Longwitz, L., &#38; Werner, T. (2020). Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis. <i>Angewandte Chemie International Edition</i>, <i>59</i>(7), 2760–2763. <a href=\"https://doi.org/10.1002/anie.201912991\">https://doi.org/10.1002/anie.201912991</a>","chicago":"Longwitz, Lars, and Thomas Werner. “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis.” <i>Angewandte Chemie International Edition</i> 59, no. 7 (2020): 2760–63. <a href=\"https://doi.org/10.1002/anie.201912991\">https://doi.org/10.1002/anie.201912991</a>.","ieee":"L. Longwitz and T. Werner, “Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis,” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 7, pp. 2760–2763, 2020, doi: <a href=\"https://doi.org/10.1002/anie.201912991\">10.1002/anie.201912991</a>.","ama":"Longwitz L, Werner T. Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis. <i>Angewandte Chemie International Edition</i>. 2020;59(7):2760-2763. doi:<a href=\"https://doi.org/10.1002/anie.201912991\">10.1002/anie.201912991</a>"},"page":"2760-2763","intvolume":"        59","publication_status":"published","publication_identifier":{"issn":["1433-7851","1521-3773"]},"issue":"7","title":"Reduction of Activated Alkenes by P<sup>III</sup>/P<sup>V</sup> Redox Cycling Catalysis","doi":"10.1002/anie.201912991","publisher":"Wiley","date_updated":"2025-11-10T08:49:52Z","author":[{"full_name":"Longwitz, Lars","last_name":"Longwitz","first_name":"Lars"},{"first_name":"Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","full_name":"Werner, Thomas","id":"89271"}],"date_created":"2025-11-05T15:39:56Z","volume":59,"abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title><jats:p>The carbon–carbon double bond of unsaturated carbonyl compounds was readily reduced by using a phosphetane oxide catalyst in the presence of a simple organosilane as the terminal reductant and water as the hydrogen source. Quantitative hydrogenation was observed when 1.0 mol % of a methyl‐substituted phosphetane oxide was employed as the catalyst. The procedure is highly selective towards activated double bonds, tolerating a variety of functional groups that are usually prone to reduction. In total, 25 alkenes and two alkynes were hydrogenated to the corresponding alkanes in excellent yields of up to 99 %. Notably, less active poly(methylhydrosiloxane) could also be utilized as the terminal reductant. Mechanistic investigations revealed the phosphane as the catalyst resting state and a protonation/deprotonation sequence as the crucial step in the catalytic cycle.</jats:p>"}],"status":"public","type":"journal_article","publication":"Angewandte Chemie International Edition","keyword":["T2","T4","CSSD"],"language":[{"iso":"eng"}],"_id":"62102","user_id":"89271","department":[{"_id":"35"},{"_id":"2"}]},{"type":"journal_article","status":"public","_id":"37953","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"user_id":"89271","extern":"1","publication_identifier":{"issn":["1864-5631","1864-564X"]},"publication_status":"published","intvolume":"        13","page":"1825-1833","citation":{"ieee":"Y. Hu <i>et al.</i>, “Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>,” <i>ChemSusChem</i>, vol. 13, no. 7, pp. 1825–1833, 2020, doi: <a href=\"https://doi.org/10.1002/cssc.201903384\">10.1002/cssc.201903384</a>.","chicago":"Hu, Yuya, Sandra Peglow, Lars Longwitz, Marcus Frank, Jan Dirk Epping, Volker Brüser, and Thomas Werner. “Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>.” <i>ChemSusChem</i> 13, no. 7 (2020): 1825–33. <a href=\"https://doi.org/10.1002/cssc.201903384\">https://doi.org/10.1002/cssc.201903384</a>.","ama":"Hu Y, Peglow S, Longwitz L, et al. Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>. <i>ChemSusChem</i>. 2020;13(7):1825-1833. doi:<a href=\"https://doi.org/10.1002/cssc.201903384\">10.1002/cssc.201903384</a>","apa":"Hu, Y., Peglow, S., Longwitz, L., Frank, M., Epping, J. D., Brüser, V., &#38; Werner, T. (2020). Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>. <i>ChemSusChem</i>, <i>13</i>(7), 1825–1833. <a href=\"https://doi.org/10.1002/cssc.201903384\">https://doi.org/10.1002/cssc.201903384</a>","short":"Y. Hu, S. Peglow, L. Longwitz, M. Frank, J.D. Epping, V. Brüser, T. Werner, ChemSusChem 13 (2020) 1825–1833.","bibtex":"@article{Hu_Peglow_Longwitz_Frank_Epping_Brüser_Werner_2020, title={Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>}, volume={13}, DOI={<a href=\"https://doi.org/10.1002/cssc.201903384\">10.1002/cssc.201903384</a>}, number={7}, journal={ChemSusChem}, publisher={Wiley}, author={Hu, Yuya and Peglow, Sandra and Longwitz, Lars and Frank, Marcus and Epping, Jan Dirk and Brüser, Volker and Werner, Thomas}, year={2020}, pages={1825–1833} }","mla":"Hu, Yuya, et al. “Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>.” <i>ChemSusChem</i>, vol. 13, no. 7, Wiley, 2020, pp. 1825–33, doi:<a href=\"https://doi.org/10.1002/cssc.201903384\">10.1002/cssc.201903384</a>."},"date_updated":"2025-11-10T08:50:25Z","volume":13,"author":[{"last_name":"Hu","full_name":"Hu, Yuya","first_name":"Yuya"},{"last_name":"Peglow","full_name":"Peglow, Sandra","first_name":"Sandra"},{"full_name":"Longwitz, Lars","last_name":"Longwitz","first_name":"Lars"},{"last_name":"Frank","full_name":"Frank, Marcus","first_name":"Marcus"},{"last_name":"Epping","full_name":"Epping, Jan Dirk","first_name":"Jan Dirk"},{"first_name":"Volker","last_name":"Brüser","full_name":"Brüser, Volker"},{"first_name":"Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","id":"89271","full_name":"Werner, Thomas"}],"doi":"10.1002/cssc.201903384","publication":"ChemSusChem","keyword":["T2","T1","CSSD"],"language":[{"iso":"eng"}],"issue":"7","year":"2020","publisher":"Wiley","date_created":"2023-01-22T20:38:11Z","title":"Plasma‐Assisted Immobilization of a Phosphonium Salt and Its Use as a Catalyst in the Valorization of CO            <sub>2</sub>"},{"year":"2020","intvolume":"        28","citation":{"apa":"Grandane, A., Nocentini, A., Werner, T., Zalubovskis, R., &#38; Supuran, C. T. (2020). Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors. <i>Bioorganic and Medicinal Chemistry</i>, <i>28</i>(11), Article 115496. <a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">https://doi.org/10.1016/j.bmc.2020.115496</a>","mla":"Grandane, Aiga, et al. “Benzoxepinones: A New Isoform-Selective Class of Tumor Associated Carbonic Anhydrase Inhibitors.” <i>Bioorganic and Medicinal Chemistry</i>, vol. 28, no. 11, 115496, Elsevier BV, 2020, doi:<a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">10.1016/j.bmc.2020.115496</a>.","bibtex":"@article{Grandane_Nocentini_Werner_Zalubovskis_Supuran_2020, title={Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors}, volume={28}, DOI={<a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">10.1016/j.bmc.2020.115496</a>}, number={11115496}, journal={Bioorganic and Medicinal Chemistry}, publisher={Elsevier BV}, author={Grandane, Aiga and Nocentini, Alessio and Werner, Thomas and Zalubovskis, Raivis and Supuran, Claudiu T.}, year={2020} }","short":"A. Grandane, A. Nocentini, T. Werner, R. Zalubovskis, C.T. Supuran, Bioorganic and Medicinal Chemistry 28 (2020).","chicago":"Grandane, Aiga, Alessio Nocentini, Thomas Werner, Raivis Zalubovskis, and Claudiu T. Supuran. “Benzoxepinones: A New Isoform-Selective Class of Tumor Associated Carbonic Anhydrase Inhibitors.” <i>Bioorganic and Medicinal Chemistry</i> 28, no. 11 (2020). <a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">https://doi.org/10.1016/j.bmc.2020.115496</a>.","ieee":"A. Grandane, A. Nocentini, T. Werner, R. Zalubovskis, and C. T. Supuran, “Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors,” <i>Bioorganic and Medicinal Chemistry</i>, vol. 28, no. 11, Art. no. 115496, 2020, doi: <a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">10.1016/j.bmc.2020.115496</a>.","ama":"Grandane A, Nocentini A, Werner T, Zalubovskis R, Supuran CT. Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors. <i>Bioorganic and Medicinal Chemistry</i>. 2020;28(11). doi:<a href=\"https://doi.org/10.1016/j.bmc.2020.115496\">10.1016/j.bmc.2020.115496</a>"},"publication_identifier":{"issn":["0968-0896"]},"publication_status":"published","issue":"11","title":"Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors","doi":"10.1016/j.bmc.2020.115496","publisher":"Elsevier BV","date_updated":"2025-11-10T08:51:24Z","volume":28,"date_created":"2023-01-22T20:36:02Z","author":[{"last_name":"Grandane","full_name":"Grandane, Aiga","first_name":"Aiga"},{"first_name":"Alessio","last_name":"Nocentini","full_name":"Nocentini, Alessio"},{"id":"89271","full_name":"Werner, Thomas","orcid":"0000-0001-9025-3244","last_name":"Werner","first_name":"Thomas"},{"first_name":"Raivis","full_name":"Zalubovskis, Raivis","last_name":"Zalubovskis"},{"first_name":"Claudiu T.","full_name":"Supuran, Claudiu T.","last_name":"Supuran"}],"status":"public","publication":"Bioorganic and Medicinal Chemistry","type":"journal_article","keyword":["T4","T2","CSSD"],"article_number":"115496","extern":"1","language":[{"iso":"eng"}],"_id":"37952","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"user_id":"89271"},{"title":"Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature","date_created":"2023-01-22T20:41:56Z","publisher":"American Chemical Society (ACS)","year":"2019","issue":"10","language":[{"iso":"eng"}],"keyword":["T2","CSSD"],"publication":"ACS Catalysis","doi":"10.1021/acscatal.9b02456","author":[{"last_name":"Longwitz","full_name":"Longwitz, Lars","first_name":"Lars"},{"first_name":"Anke","full_name":"Spannenberg, Anke","last_name":"Spannenberg"},{"first_name":"Thomas","orcid":"0000-0001-9025-3244","last_name":"Werner","full_name":"Werner, Thomas","id":"89271"}],"volume":9,"date_updated":"2025-11-10T08:54:03Z","citation":{"mla":"Longwitz, Lars, et al. “Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature.” <i>ACS Catalysis</i>, vol. 9, no. 10, American Chemical Society (ACS), 2019, pp. 9237–44, doi:<a href=\"https://doi.org/10.1021/acscatal.9b02456\">10.1021/acscatal.9b02456</a>.","bibtex":"@article{Longwitz_Spannenberg_Werner_2019, title={Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature}, volume={9}, DOI={<a href=\"https://doi.org/10.1021/acscatal.9b02456\">10.1021/acscatal.9b02456</a>}, number={10}, journal={ACS Catalysis}, publisher={American Chemical Society (ACS)}, author={Longwitz, Lars and Spannenberg, Anke and Werner, Thomas}, year={2019}, pages={9237–9244} }","short":"L. Longwitz, A. Spannenberg, T. Werner, ACS Catalysis 9 (2019) 9237–9244.","apa":"Longwitz, L., Spannenberg, A., &#38; Werner, T. (2019). Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature. <i>ACS Catalysis</i>, <i>9</i>(10), 9237–9244. <a href=\"https://doi.org/10.1021/acscatal.9b02456\">https://doi.org/10.1021/acscatal.9b02456</a>","ama":"Longwitz L, Spannenberg A, Werner T. Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature. <i>ACS Catalysis</i>. 2019;9(10):9237-9244. doi:<a href=\"https://doi.org/10.1021/acscatal.9b02456\">10.1021/acscatal.9b02456</a>","ieee":"L. Longwitz, A. Spannenberg, and T. Werner, “Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature,” <i>ACS Catalysis</i>, vol. 9, no. 10, pp. 9237–9244, 2019, doi: <a href=\"https://doi.org/10.1021/acscatal.9b02456\">10.1021/acscatal.9b02456</a>.","chicago":"Longwitz, Lars, Anke Spannenberg, and Thomas Werner. “Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature.” <i>ACS Catalysis</i> 9, no. 10 (2019): 9237–44. <a href=\"https://doi.org/10.1021/acscatal.9b02456\">https://doi.org/10.1021/acscatal.9b02456</a>."},"intvolume":"         9","page":"9237-9244","publication_status":"published","publication_identifier":{"issn":["2155-5435","2155-5435"]},"extern":"1","user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"_id":"37958","status":"public","type":"journal_article"},{"title":"Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling","doi":"10.1021/acs.joc.9b00741","publisher":"American Chemical Society (ACS)","date_updated":"2025-11-10T08:54:28Z","author":[{"last_name":"Longwitz","full_name":"Longwitz, Lars","first_name":"Lars"},{"first_name":"Stefan","full_name":"Jopp, Stefan","last_name":"Jopp"},{"orcid":"0000-0001-9025-3244","last_name":"Werner","id":"89271","full_name":"Werner, Thomas","first_name":"Thomas"}],"date_created":"2023-01-22T20:44:02Z","volume":84,"year":"2019","citation":{"short":"L. Longwitz, S. Jopp, T. Werner, The Journal of Organic Chemistry 84 (2019) 7863–7870.","mla":"Longwitz, Lars, et al. “Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling.” <i>The Journal of Organic Chemistry</i>, vol. 84, no. 12, American Chemical Society (ACS), 2019, pp. 7863–70, doi:<a href=\"https://doi.org/10.1021/acs.joc.9b00741\">10.1021/acs.joc.9b00741</a>.","bibtex":"@article{Longwitz_Jopp_Werner_2019, title={Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling}, volume={84}, DOI={<a href=\"https://doi.org/10.1021/acs.joc.9b00741\">10.1021/acs.joc.9b00741</a>}, number={12}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Longwitz, Lars and Jopp, Stefan and Werner, Thomas}, year={2019}, pages={7863–7870} }","apa":"Longwitz, L., Jopp, S., &#38; Werner, T. (2019). Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling. <i>The Journal of Organic Chemistry</i>, <i>84</i>(12), 7863–7870. <a href=\"https://doi.org/10.1021/acs.joc.9b00741\">https://doi.org/10.1021/acs.joc.9b00741</a>","ama":"Longwitz L, Jopp S, Werner T. Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling. <i>The Journal of Organic Chemistry</i>. 2019;84(12):7863-7870. doi:<a href=\"https://doi.org/10.1021/acs.joc.9b00741\">10.1021/acs.joc.9b00741</a>","ieee":"L. Longwitz, S. Jopp, and T. Werner, “Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling,” <i>The Journal of Organic Chemistry</i>, vol. 84, no. 12, pp. 7863–7870, 2019, doi: <a href=\"https://doi.org/10.1021/acs.joc.9b00741\">10.1021/acs.joc.9b00741</a>.","chicago":"Longwitz, Lars, Stefan Jopp, and Thomas Werner. “Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling.” <i>The Journal of Organic Chemistry</i> 84, no. 12 (2019): 7863–70. <a href=\"https://doi.org/10.1021/acs.joc.9b00741\">https://doi.org/10.1021/acs.joc.9b00741</a>."},"intvolume":"        84","page":"7863-7870","publication_status":"published","publication_identifier":{"issn":["0022-3263","1520-6904"]},"issue":"12","keyword":["T2","CSSD"],"extern":"1","language":[{"iso":"eng"}],"_id":"37962","user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"status":"public","type":"journal_article","publication":"The Journal of Organic Chemistry"},{"abstract":[{"lang":"eng","text":"<jats:p>Catalytic nucleophilic substitution of alcohols makes organic synthesis greener</jats:p>"}],"publication":"Science","keyword":["T2","CSSD"],"language":[{"iso":"eng"}],"year":"2019","issue":"6456","title":"The Mitsunobu reaction, reimagined","publisher":"American Association for the Advancement of Science (AAAS)","date_created":"2023-01-22T20:42:20Z","status":"public","type":"journal_article","_id":"37959","user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"citation":{"bibtex":"@article{Longwitz_Werner_2019, title={The Mitsunobu reaction, reimagined}, volume={365}, DOI={<a href=\"https://doi.org/10.1126/science.aay6635\">10.1126/science.aay6635</a>}, number={6456}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Longwitz, Lars and Werner, Thomas}, year={2019}, pages={866–867} }","short":"L. Longwitz, T. Werner, Science 365 (2019) 866–867.","mla":"Longwitz, Lars, and Thomas Werner. “The Mitsunobu Reaction, Reimagined.” <i>Science</i>, vol. 365, no. 6456, American Association for the Advancement of Science (AAAS), 2019, pp. 866–67, doi:<a href=\"https://doi.org/10.1126/science.aay6635\">10.1126/science.aay6635</a>.","apa":"Longwitz, L., &#38; Werner, T. (2019). The Mitsunobu reaction, reimagined. <i>Science</i>, <i>365</i>(6456), 866–867. <a href=\"https://doi.org/10.1126/science.aay6635\">https://doi.org/10.1126/science.aay6635</a>","ama":"Longwitz L, Werner T. The Mitsunobu reaction, reimagined. <i>Science</i>. 2019;365(6456):866-867. doi:<a href=\"https://doi.org/10.1126/science.aay6635\">10.1126/science.aay6635</a>","chicago":"Longwitz, Lars, and Thomas Werner. “The Mitsunobu Reaction, Reimagined.” <i>Science</i> 365, no. 6456 (2019): 866–67. <a href=\"https://doi.org/10.1126/science.aay6635\">https://doi.org/10.1126/science.aay6635</a>.","ieee":"L. Longwitz and T. Werner, “The Mitsunobu reaction, reimagined,” <i>Science</i>, vol. 365, no. 6456, pp. 866–867, 2019, doi: <a href=\"https://doi.org/10.1126/science.aay6635\">10.1126/science.aay6635</a>."},"page":"866-867","intvolume":"       365","publication_status":"published","publication_identifier":{"issn":["0036-8075","1095-9203"]},"doi":"10.1126/science.aay6635","date_updated":"2025-11-10T09:01:38Z","author":[{"last_name":"Longwitz","full_name":"Longwitz, Lars","first_name":"Lars"},{"full_name":"Werner, Thomas","id":"89271","orcid":"0000-0001-9025-3244","last_name":"Werner","first_name":"Thomas"}],"volume":365},{"user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"_id":"37966","extern":"1","language":[{"iso":"eng"}],"keyword":["T2","CSSD"],"type":"journal_article","publication":"Pure and Applied Chemistry","status":"public","abstract":[{"lang":"eng","text":"<jats:title>Abstract</jats:title>\r\n               <jats:p>Numerous organic transformations are based on the use of stoichiometric amounts of phosphorus reagents. The formation of phosphane oxides from phosphanes is usually the thermodynamic driving force for these reactions. The stoichiometric amounts of phosphane oxide which are formed as by-products often significantly hamper the product purification. Organophosphorus catalysis based on P(III)/P(V) redox cycling aims to address these problems. Herein we present our recent advances in developing catalytic Wittig-type reactions. More specifically, we reported our results on catalytic Wittig reactions based on readily available Bu<jats:sub>3</jats:sub>P=O as pre-catalyst as well as the first microwave-assisted version of this reaction and the first enantioselective catalytic Wittig reaction utilizing chiral phosphane catalysts. Further developments led to the implementation of catalytic base-free Wittig reactions yielding highly functionalized alkylidene and arylidene succinates.</jats:p>"}],"author":[{"first_name":"Lars","last_name":"Longwitz","full_name":"Longwitz, Lars"},{"first_name":"Thomas","last_name":"Werner","orcid":"0000-0001-9025-3244","id":"89271","full_name":"Werner, Thomas"}],"date_created":"2023-01-22T20:45:38Z","volume":91,"date_updated":"2025-11-10T09:06:58Z","publisher":"Walter de Gruyter GmbH","doi":"10.1515/pac-2018-0920","title":"Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling","issue":"1","publication_status":"published","publication_identifier":{"issn":["1365-3075","0033-4545"]},"citation":{"ieee":"L. Longwitz and T. Werner, “Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling,” <i>Pure and Applied Chemistry</i>, vol. 91, no. 1, pp. 95–102, 2019, doi: <a href=\"https://doi.org/10.1515/pac-2018-0920\">10.1515/pac-2018-0920</a>.","chicago":"Longwitz, Lars, and Thomas Werner. “Recent Advances in Catalytic Wittig-Type Reactions Based on P(III)/P(V) Redox Cycling.” <i>Pure and Applied Chemistry</i> 91, no. 1 (2019): 95–102. <a href=\"https://doi.org/10.1515/pac-2018-0920\">https://doi.org/10.1515/pac-2018-0920</a>.","ama":"Longwitz L, Werner T. Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling. <i>Pure and Applied Chemistry</i>. 2019;91(1):95-102. doi:<a href=\"https://doi.org/10.1515/pac-2018-0920\">10.1515/pac-2018-0920</a>","short":"L. Longwitz, T. Werner, Pure and Applied Chemistry 91 (2019) 95–102.","mla":"Longwitz, Lars, and Thomas Werner. “Recent Advances in Catalytic Wittig-Type Reactions Based on P(III)/P(V) Redox Cycling.” <i>Pure and Applied Chemistry</i>, vol. 91, no. 1, Walter de Gruyter GmbH, 2019, pp. 95–102, doi:<a href=\"https://doi.org/10.1515/pac-2018-0920\">10.1515/pac-2018-0920</a>.","bibtex":"@article{Longwitz_Werner_2019, title={Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling}, volume={91}, DOI={<a href=\"https://doi.org/10.1515/pac-2018-0920\">10.1515/pac-2018-0920</a>}, number={1}, journal={Pure and Applied Chemistry}, publisher={Walter de Gruyter GmbH}, author={Longwitz, Lars and Werner, Thomas}, year={2019}, pages={95–102} }","apa":"Longwitz, L., &#38; Werner, T. (2019). Recent advances in catalytic Wittig-type reactions based on P(III)/P(V) redox cycling. <i>Pure and Applied Chemistry</i>, <i>91</i>(1), 95–102. <a href=\"https://doi.org/10.1515/pac-2018-0920\">https://doi.org/10.1515/pac-2018-0920</a>"},"intvolume":"        91","page":"95-102","year":"2019"},{"year":"2019","issue":"3","title":"Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones","date_created":"2023-01-22T20:45:12Z","publisher":"American Chemical Society (ACS)","publication":"The Journal of Organic Chemistry","language":[{"iso":"eng"}],"keyword":["T2","T4","CSSD"],"citation":{"apa":"Grandane, A., Longwitz, L., Roolf, C., Spannenberg, A., Murua Escobar, H., Junghanss, C., Suna, E., &#38; Werner, T. (2019). Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones. <i>The Journal of Organic Chemistry</i>, <i>84</i>(3), 1320–1329. <a href=\"https://doi.org/10.1021/acs.joc.8b02789\">https://doi.org/10.1021/acs.joc.8b02789</a>","bibtex":"@article{Grandane_Longwitz_Roolf_Spannenberg_Murua Escobar_Junghanss_Suna_Werner_2019, title={Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones}, volume={84}, DOI={<a href=\"https://doi.org/10.1021/acs.joc.8b02789\">10.1021/acs.joc.8b02789</a>}, number={3}, journal={The Journal of Organic Chemistry}, publisher={American Chemical Society (ACS)}, author={Grandane, Aiga and Longwitz, Lars and Roolf, Catrin and Spannenberg, Anke and Murua Escobar, Hugo and Junghanss, Christian and Suna, Edgars and Werner, Thomas}, year={2019}, pages={1320–1329} }","short":"A. Grandane, L. Longwitz, C. Roolf, A. Spannenberg, H. Murua Escobar, C. Junghanss, E. Suna, T. Werner, The Journal of Organic Chemistry 84 (2019) 1320–1329.","mla":"Grandane, Aiga, et al. “Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones.” <i>The Journal of Organic Chemistry</i>, vol. 84, no. 3, American Chemical Society (ACS), 2019, pp. 1320–29, doi:<a href=\"https://doi.org/10.1021/acs.joc.8b02789\">10.1021/acs.joc.8b02789</a>.","chicago":"Grandane, Aiga, Lars Longwitz, Catrin Roolf, Anke Spannenberg, Hugo Murua Escobar, Christian Junghanss, Edgars Suna, and Thomas Werner. “Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones.” <i>The Journal of Organic Chemistry</i> 84, no. 3 (2019): 1320–29. <a href=\"https://doi.org/10.1021/acs.joc.8b02789\">https://doi.org/10.1021/acs.joc.8b02789</a>.","ieee":"A. Grandane <i>et al.</i>, “Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones,” <i>The Journal of Organic Chemistry</i>, vol. 84, no. 3, pp. 1320–1329, 2019, doi: <a href=\"https://doi.org/10.1021/acs.joc.8b02789\">10.1021/acs.joc.8b02789</a>.","ama":"Grandane A, Longwitz L, Roolf C, et al. Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones. <i>The Journal of Organic Chemistry</i>. 2019;84(3):1320-1329. doi:<a href=\"https://doi.org/10.1021/acs.joc.8b02789\">10.1021/acs.joc.8b02789</a>"},"page":"1320-1329","intvolume":"        84","publication_status":"published","publication_identifier":{"issn":["0022-3263","1520-6904"]},"doi":"10.1021/acs.joc.8b02789","author":[{"first_name":"Aiga","full_name":"Grandane, Aiga","last_name":"Grandane"},{"full_name":"Longwitz, Lars","last_name":"Longwitz","first_name":"Lars"},{"first_name":"Catrin","last_name":"Roolf","full_name":"Roolf, Catrin"},{"full_name":"Spannenberg, Anke","last_name":"Spannenberg","first_name":"Anke"},{"full_name":"Murua Escobar, Hugo","last_name":"Murua Escobar","first_name":"Hugo"},{"last_name":"Junghanss","full_name":"Junghanss, Christian","first_name":"Christian"},{"first_name":"Edgars","last_name":"Suna","full_name":"Suna, Edgars"},{"last_name":"Werner","orcid":"0000-0001-9025-3244","full_name":"Werner, Thomas","id":"89271","first_name":"Thomas"}],"volume":84,"date_updated":"2025-11-10T09:10:18Z","status":"public","type":"journal_article","extern":"1","user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"_id":"37965"},{"doi":"10.1021/acssuschemeng.8b02093","date_updated":"2025-11-10T09:04:50Z","volume":6,"author":[{"last_name":"Steinbauer","full_name":"Steinbauer, Johannes","first_name":"Johannes"},{"first_name":"Christoph","last_name":"Kubis","full_name":"Kubis, Christoph"},{"last_name":"Ludwig","full_name":"Ludwig, Ralf","first_name":"Ralf"},{"first_name":"Thomas","full_name":"Werner, Thomas","id":"89271","orcid":"0000-0001-9025-3244","last_name":"Werner"}],"page":"10778-10788","intvolume":"         6","citation":{"short":"J. Steinbauer, C. Kubis, R. Ludwig, T. Werner, ACS Sustainable Chemistry and Engineering 6 (2018) 10778–10788.","bibtex":"@article{Steinbauer_Kubis_Ludwig_Werner_2018, title={Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach}, volume={6}, DOI={<a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">10.1021/acssuschemeng.8b02093</a>}, number={8}, journal={ACS Sustainable Chemistry and Engineering}, publisher={American Chemical Society (ACS)}, author={Steinbauer, Johannes and Kubis, Christoph and Ludwig, Ralf and Werner, Thomas}, year={2018}, pages={10778–10788} }","mla":"Steinbauer, Johannes, et al. “Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach.” <i>ACS Sustainable Chemistry and Engineering</i>, vol. 6, no. 8, American Chemical Society (ACS), 2018, pp. 10778–88, doi:<a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">10.1021/acssuschemeng.8b02093</a>.","apa":"Steinbauer, J., Kubis, C., Ludwig, R., &#38; Werner, T. (2018). Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach. <i>ACS Sustainable Chemistry and Engineering</i>, <i>6</i>(8), 10778–10788. <a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">https://doi.org/10.1021/acssuschemeng.8b02093</a>","chicago":"Steinbauer, Johannes, Christoph Kubis, Ralf Ludwig, and Thomas Werner. “Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach.” <i>ACS Sustainable Chemistry and Engineering</i> 6, no. 8 (2018): 10778–88. <a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">https://doi.org/10.1021/acssuschemeng.8b02093</a>.","ieee":"J. Steinbauer, C. Kubis, R. Ludwig, and T. Werner, “Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach,” <i>ACS Sustainable Chemistry and Engineering</i>, vol. 6, no. 8, pp. 10778–10788, 2018, doi: <a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">10.1021/acssuschemeng.8b02093</a>.","ama":"Steinbauer J, Kubis C, Ludwig R, Werner T. Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach. <i>ACS Sustainable Chemistry and Engineering</i>. 2018;6(8):10778-10788. doi:<a href=\"https://doi.org/10.1021/acssuschemeng.8b02093\">10.1021/acssuschemeng.8b02093</a>"},"publication_identifier":{"issn":["2168-0485","2168-0485"]},"publication_status":"published","extern":"1","_id":"37967","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"user_id":"89271","status":"public","type":"journal_article","title":"Mechanistic Study on the Addition of CO<sub>2</sub> to Epoxides Catalyzed by Ammonium and Phosphonium Salts: A Combined Spectroscopic and Kinetic Approach","publisher":"American Chemical Society (ACS)","date_created":"2023-01-22T20:46:04Z","year":"2018","issue":"8","keyword":["T1","T2","CSSD"],"language":[{"iso":"eng"}],"publication":"ACS Sustainable Chemistry and Engineering"},{"issue":"18","publication_status":"published","publication_identifier":{"issn":["1463-9262","1463-9270"]},"citation":{"bibtex":"@article{Steinbauer_Longwitz_Frank_Epping_Kragl_Werner_2017, title={Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO<sub>2</sub> and epoxides}, volume={19}, DOI={<a href=\"https://doi.org/10.1039/c7gc01782k\">10.1039/c7gc01782k</a>}, number={18}, journal={Green Chemistry}, publisher={Royal Society of Chemistry (RSC)}, author={Steinbauer, J. and Longwitz, L. and Frank, M. and Epping, J. and Kragl, U. and Werner, Thomas}, year={2017}, pages={4435–4445} }","mla":"Steinbauer, J., et al. “Immobilized Bifunctional Phosphonium Salts as Recyclable Organocatalysts in the Cycloaddition of CO<sub>2</sub> and Epoxides.” <i>Green Chemistry</i>, vol. 19, no. 18, Royal Society of Chemistry (RSC), 2017, pp. 4435–45, doi:<a href=\"https://doi.org/10.1039/c7gc01782k\">10.1039/c7gc01782k</a>.","short":"J. Steinbauer, L. Longwitz, M. Frank, J. Epping, U. Kragl, T. Werner, Green Chemistry 19 (2017) 4435–4445.","apa":"Steinbauer, J., Longwitz, L., Frank, M., Epping, J., Kragl, U., &#38; Werner, T. (2017). Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO<sub>2</sub> and epoxides. <i>Green Chemistry</i>, <i>19</i>(18), 4435–4445. <a href=\"https://doi.org/10.1039/c7gc01782k\">https://doi.org/10.1039/c7gc01782k</a>","ama":"Steinbauer J, Longwitz L, Frank M, Epping J, Kragl U, Werner T. Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO<sub>2</sub> and epoxides. <i>Green Chemistry</i>. 2017;19(18):4435-4445. doi:<a href=\"https://doi.org/10.1039/c7gc01782k\">10.1039/c7gc01782k</a>","chicago":"Steinbauer, J., L. Longwitz, M. Frank, J. Epping, U. Kragl, and Thomas Werner. “Immobilized Bifunctional Phosphonium Salts as Recyclable Organocatalysts in the Cycloaddition of CO<sub>2</sub> and Epoxides.” <i>Green Chemistry</i> 19, no. 18 (2017): 4435–45. <a href=\"https://doi.org/10.1039/c7gc01782k\">https://doi.org/10.1039/c7gc01782k</a>.","ieee":"J. Steinbauer, L. Longwitz, M. Frank, J. Epping, U. Kragl, and T. Werner, “Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO<sub>2</sub> and epoxides,” <i>Green Chemistry</i>, vol. 19, no. 18, pp. 4435–4445, 2017, doi: <a href=\"https://doi.org/10.1039/c7gc01782k\">10.1039/c7gc01782k</a>."},"page":"4435-4445","intvolume":"        19","year":"2017","author":[{"first_name":"J.","last_name":"Steinbauer","full_name":"Steinbauer, J."},{"full_name":"Longwitz, L.","last_name":"Longwitz","first_name":"L."},{"first_name":"M.","last_name":"Frank","full_name":"Frank, M."},{"first_name":"J.","full_name":"Epping, J.","last_name":"Epping"},{"first_name":"U.","last_name":"Kragl","full_name":"Kragl, U."},{"id":"89271","full_name":"Werner, Thomas","orcid":"0000-0001-9025-3244","last_name":"Werner","first_name":"Thomas"}],"date_created":"2023-01-22T20:57:38Z","volume":19,"date_updated":"2025-11-10T09:18:10Z","publisher":"Royal Society of Chemistry (RSC)","doi":"10.1039/c7gc01782k","title":"Immobilized bifunctional phosphonium salts as recyclable organocatalysts in the cycloaddition of CO<sub>2</sub> and epoxides","type":"journal_article","publication":"Green Chemistry","status":"public","abstract":[{"text":"<p>An immobilized bifunctional phosphonium salt catalyst efficiently catalyzed the synthesis of cyclic carbonates under mild conditions, and was reused up to 15 times.</p>","lang":"eng"}],"user_id":"89271","department":[{"_id":"35"},{"_id":"2"},{"_id":"657"}],"_id":"37973","language":[{"iso":"eng"}],"extern":"1","keyword":["T1","T2","CSSD"]}]