[{"type":"journal_article","status":"public","user_id":"62844","department":[{"_id":"311"}],"_id":"59620","article_type":"original","publication_status":"published","publication_identifier":{"issn":["2637-6105","2637-6105"]},"citation":{"ieee":"T. Rust, D. Jung, A. Hoppe, T. Schoppa, K. Langer, and D. Kuckling, “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery,” <i>ACS Applied Polymer Materials</i>, vol. 3, no. 8, pp. 3831–3842, 2021, doi: <a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>.","chicago":"Rust, Tarik, Dimitri Jung, Axel Hoppe, Timo Schoppa, Klaus Langer, and Dirk Kuckling. “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery.” <i>ACS Applied Polymer Materials</i> 3, no. 8 (2021): 3831–42. <a href=\"https://doi.org/10.1021/acsapm.1c00411\">https://doi.org/10.1021/acsapm.1c00411</a>.","ama":"Rust T, Jung D, Hoppe A, Schoppa T, Langer K, Kuckling D. Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery. <i>ACS Applied Polymer Materials</i>. 2021;3(8):3831-3842. doi:<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>","apa":"Rust, T., Jung, D., Hoppe, A., Schoppa, T., Langer, K., &#38; Kuckling, D. (2021). Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery. <i>ACS Applied Polymer Materials</i>, <i>3</i>(8), 3831–3842. <a href=\"https://doi.org/10.1021/acsapm.1c00411\">https://doi.org/10.1021/acsapm.1c00411</a>","mla":"Rust, Tarik, et al. “Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery.” <i>ACS Applied Polymer Materials</i>, vol. 3, no. 8, American Chemical Society (ACS), 2021, pp. 3831–42, doi:<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>.","bibtex":"@article{Rust_Jung_Hoppe_Schoppa_Langer_Kuckling_2021, title={Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery}, volume={3}, DOI={<a href=\"https://doi.org/10.1021/acsapm.1c00411\">10.1021/acsapm.1c00411</a>}, number={8}, journal={ACS Applied Polymer Materials}, publisher={American Chemical Society (ACS)}, author={Rust, Tarik and Jung, Dimitri and Hoppe, Axel and Schoppa, Timo and Langer, Klaus and Kuckling, Dirk}, year={2021}, pages={3831–3842} }","short":"T. Rust, D. Jung, A. Hoppe, T. Schoppa, K. Langer, D. Kuckling, ACS Applied Polymer Materials 3 (2021) 3831–3842."},"page":"3831-3842","intvolume":"         3","author":[{"first_name":"Tarik","full_name":"Rust, Tarik","last_name":"Rust"},{"full_name":"Jung, Dimitri","last_name":"Jung","first_name":"Dimitri"},{"last_name":"Hoppe","full_name":"Hoppe, Axel","id":"62844","first_name":"Axel"},{"last_name":"Schoppa","full_name":"Schoppa, Timo","first_name":"Timo"},{"first_name":"Klaus","last_name":"Langer","full_name":"Langer, Klaus"},{"first_name":"Dirk","full_name":"Kuckling, Dirk","id":"287","last_name":"Kuckling"}],"volume":3,"date_updated":"2025-04-22T06:12:02Z","main_file_link":[{"url":"https://pubs.acs.org/doi/10.1021/acsapm.1c00411?ref=PDF"}],"doi":"10.1021/acsapm.1c00411","publication":"ACS Applied Polymer Materials","language":[{"iso":"eng"}],"keyword":["backbone-degradable","light-responsive","redox-responsive","drug delivery","nanoparticles"],"issue":"8","quality_controlled":"1","year":"2021","date_created":"2025-04-22T06:02:11Z","publisher":"American Chemical Society (ACS)","title":"Backbone-Degradable (Co-)Polymers for Light-Triggered Drug Delivery"},{"year":"2019","citation":{"mla":"Mahlert, Laura, et al. “In Vitro Evaluation of Innovative Light-Responsive Nanoparticles for Controlled Drug Release in Intestinal PDT.” <i>International Journal of Pharmaceutics</i>, vol. 565, Elsevier BV, 2019, pp. 199–208, doi:<a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">10.1016/j.ijpharm.2019.04.077</a>.","bibtex":"@article{Mahlert_Anderski_Schoppa_Mulac_Sun_Kuckling_Langer_2019, title={In vitro evaluation of innovative light-responsive nanoparticles for controlled drug release in intestinal PDT}, volume={565}, DOI={<a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">10.1016/j.ijpharm.2019.04.077</a>}, journal={International Journal of Pharmaceutics}, publisher={Elsevier BV}, author={Mahlert, Laura and Anderski, Juliane and Schoppa, Timo and Mulac, Dennis and Sun, Jingjiang and Kuckling, Dirk and Langer, Klaus}, year={2019}, pages={199–208} }","short":"L. Mahlert, J. Anderski, T. Schoppa, D. Mulac, J. Sun, D. Kuckling, K. Langer, International Journal of Pharmaceutics 565 (2019) 199–208.","apa":"Mahlert, L., Anderski, J., Schoppa, T., Mulac, D., Sun, J., Kuckling, D., &#38; Langer, K. (2019). In vitro evaluation of innovative light-responsive nanoparticles for controlled drug release in intestinal PDT. <i>International Journal of Pharmaceutics</i>, <i>565</i>, 199–208. <a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">https://doi.org/10.1016/j.ijpharm.2019.04.077</a>","chicago":"Mahlert, Laura, Juliane Anderski, Timo Schoppa, Dennis Mulac, Jingjiang Sun, Dirk Kuckling, and Klaus Langer. “In Vitro Evaluation of Innovative Light-Responsive Nanoparticles for Controlled Drug Release in Intestinal PDT.” <i>International Journal of Pharmaceutics</i> 565 (2019): 199–208. <a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">https://doi.org/10.1016/j.ijpharm.2019.04.077</a>.","ieee":"L. Mahlert <i>et al.</i>, “In vitro evaluation of innovative light-responsive nanoparticles for controlled drug release in intestinal PDT,” <i>International Journal of Pharmaceutics</i>, vol. 565, pp. 199–208, 2019, doi: <a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">10.1016/j.ijpharm.2019.04.077</a>.","ama":"Mahlert L, Anderski J, Schoppa T, et al. In vitro evaluation of innovative light-responsive nanoparticles for controlled drug release in intestinal PDT. <i>International Journal of Pharmaceutics</i>. 2019;565:199-208. doi:<a href=\"https://doi.org/10.1016/j.ijpharm.2019.04.077\">10.1016/j.ijpharm.2019.04.077</a>"},"page":"199-208","intvolume":"       565","publication_status":"published","publication_identifier":{"issn":["0378-5173"]},"title":"In vitro evaluation of innovative light-responsive nanoparticles for controlled drug release in intestinal PDT","doi":"10.1016/j.ijpharm.2019.04.077","publisher":"Elsevier BV","date_updated":"2022-04-21T09:13:07Z","author":[{"last_name":"Mahlert","full_name":"Mahlert, Laura","first_name":"Laura"},{"full_name":"Anderski, Juliane","last_name":"Anderski","first_name":"Juliane"},{"first_name":"Timo","full_name":"Schoppa, Timo","last_name":"Schoppa"},{"first_name":"Dennis","full_name":"Mulac, Dennis","last_name":"Mulac"},{"first_name":"Jingjiang","last_name":"Sun","full_name":"Sun, Jingjiang"},{"first_name":"Dirk","last_name":"Kuckling","full_name":"Kuckling, Dirk","id":"287"},{"first_name":"Klaus","last_name":"Langer","full_name":"Langer, Klaus"}],"date_created":"2022-04-21T09:12:07Z","volume":565,"status":"public","type":"journal_article","publication":"International Journal of Pharmaceutics","keyword":["Light-responsive polymersPhotodynamic therapyControlled drug deliveryHT-29-MTX cellsIntestinal cancer"],"language":[{"iso":"eng"}],"_id":"30934","user_id":"94","department":[{"_id":"311"}]},{"status":"public","type":"journal_article","publication":"ACS Applied Bio Materials","language":[{"iso":"eng"}],"keyword":["light-responsive polymers","biodegradable polymers","polycondensation"],"user_id":"94","department":[{"_id":"311"}],"_id":"30936","citation":{"apa":"Sun, J., Jung, D., Schoppa, T., Anderski, J., Picker, M.-T., Ren, Y., Mulac, D., Stein, N., Langer, K., &#38; Kuckling, D. (2019). Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds. <i>ACS Applied Bio Materials</i>, <i>2</i>(7), 3038–3051. <a href=\"https://doi.org/10.1021/acsabm.9b00347\">https://doi.org/10.1021/acsabm.9b00347</a>","short":"J. Sun, D. Jung, T. Schoppa, J. Anderski, M.-T. Picker, Y. Ren, D. Mulac, N. Stein, K. Langer, D. Kuckling, ACS Applied Bio Materials 2 (2019) 3038–3051.","bibtex":"@article{Sun_Jung_Schoppa_Anderski_Picker_Ren_Mulac_Stein_Langer_Kuckling_2019, title={Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds}, volume={2}, DOI={<a href=\"https://doi.org/10.1021/acsabm.9b00347\">10.1021/acsabm.9b00347</a>}, number={7}, journal={ACS Applied Bio Materials}, publisher={American Chemical Society (ACS)}, author={Sun, Jingjiang and Jung, Dimitri and Schoppa, Timo and Anderski, Juliane and Picker, Marie-Theres and Ren, Yi and Mulac, Dennis and Stein, Nora and Langer, Klaus and Kuckling, Dirk}, year={2019}, pages={3038–3051} }","mla":"Sun, Jingjiang, et al. “Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds.” <i>ACS Applied Bio Materials</i>, vol. 2, no. 7, American Chemical Society (ACS), 2019, pp. 3038–51, doi:<a href=\"https://doi.org/10.1021/acsabm.9b00347\">10.1021/acsabm.9b00347</a>.","ieee":"J. Sun <i>et al.</i>, “Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds,” <i>ACS Applied Bio Materials</i>, vol. 2, no. 7, pp. 3038–3051, 2019, doi: <a href=\"https://doi.org/10.1021/acsabm.9b00347\">10.1021/acsabm.9b00347</a>.","chicago":"Sun, Jingjiang, Dimitri Jung, Timo Schoppa, Juliane Anderski, Marie-Theres Picker, Yi Ren, Dennis Mulac, Nora Stein, Klaus Langer, and Dirk Kuckling. “Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds.” <i>ACS Applied Bio Materials</i> 2, no. 7 (2019): 3038–51. <a href=\"https://doi.org/10.1021/acsabm.9b00347\">https://doi.org/10.1021/acsabm.9b00347</a>.","ama":"Sun J, Jung D, Schoppa T, et al. Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds. <i>ACS Applied Bio Materials</i>. 2019;2(7):3038-3051. doi:<a href=\"https://doi.org/10.1021/acsabm.9b00347\">10.1021/acsabm.9b00347</a>"},"page":"3038-3051","intvolume":"         2","year":"2019","issue":"7","publication_status":"published","publication_identifier":{"issn":["2576-6422","2576-6422"]},"doi":"10.1021/acsabm.9b00347","title":"Light-Responsive Serinol-Based Polycarbonate and Polyester as Degradable Scaffolds","date_created":"2022-04-21T09:15:22Z","author":[{"first_name":"Jingjiang","last_name":"Sun","full_name":"Sun, Jingjiang"},{"first_name":"Dimitri","last_name":"Jung","full_name":"Jung, Dimitri"},{"full_name":"Schoppa, Timo","last_name":"Schoppa","first_name":"Timo"},{"full_name":"Anderski, Juliane","last_name":"Anderski","first_name":"Juliane"},{"full_name":"Picker, Marie-Theres","last_name":"Picker","first_name":"Marie-Theres"},{"first_name":"Yi","last_name":"Ren","full_name":"Ren, Yi"},{"first_name":"Dennis","last_name":"Mulac","full_name":"Mulac, Dennis"},{"first_name":"Nora","last_name":"Stein","full_name":"Stein, Nora"},{"first_name":"Klaus","last_name":"Langer","full_name":"Langer, Klaus"},{"last_name":"Kuckling","id":"287","full_name":"Kuckling, Dirk","first_name":"Dirk"}],"volume":2,"date_updated":"2022-04-21T09:16:31Z","publisher":"American Chemical Society (ACS)"},{"date_updated":"2022-01-06T06:51:30Z","author":[{"last_name":"Rösener","full_name":"Rösener, Thomas","first_name":"Thomas"},{"last_name":"Hoffmann","full_name":"Hoffmann, Alexander","first_name":"Alexander"},{"first_name":"Sonja","last_name":"Herres-Pawlis","full_name":"Herres-Pawlis, Sonja"}],"date_created":"2019-09-11T11:00:06Z","volume":2018,"title":"Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility","doi":"10.1002/ejic.201800511","issue":"27","year":"2018","citation":{"apa":"Rösener, T., Hoffmann, A., &#38; Herres-Pawlis, S. (2018). Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility. <i>European Journal of Inorganic Chemistry</i>, <i>2018</i>(27), 3164–3175. <a href=\"https://doi.org/10.1002/ejic.201800511\">https://doi.org/10.1002/ejic.201800511</a>","short":"T. Rösener, A. Hoffmann, S. Herres-Pawlis, European Journal of Inorganic Chemistry 2018 (2018) 3164–3175.","mla":"Rösener, Thomas, et al. “Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility.” <i>European Journal of Inorganic Chemistry</i>, vol. 2018, no. 27, 2018, pp. 3164–75, doi:<a href=\"https://doi.org/10.1002/ejic.201800511\">10.1002/ejic.201800511</a>.","bibtex":"@article{Rösener_Hoffmann_Herres-Pawlis_2018, title={Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility}, volume={2018}, DOI={<a href=\"https://doi.org/10.1002/ejic.201800511\">10.1002/ejic.201800511</a>}, number={27}, journal={European Journal of Inorganic Chemistry}, author={Rösener, Thomas and Hoffmann, Alexander and Herres-Pawlis, Sonja}, year={2018}, pages={3164–3175} }","ama":"Rösener T, Hoffmann A, Herres-Pawlis S. Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility. <i>European Journal of Inorganic Chemistry</i>. 2018;2018(27):3164-3175. doi:<a href=\"https://doi.org/10.1002/ejic.201800511\">10.1002/ejic.201800511</a>","ieee":"T. Rösener, A. Hoffmann, and S. Herres-Pawlis, “Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility,” <i>European Journal of Inorganic Chemistry</i>, vol. 2018, no. 27, pp. 3164–3175, 2018.","chicago":"Rösener, Thomas, Alexander Hoffmann, and Sonja Herres-Pawlis. “Next Generation of Guanidine Quinoline Copper Complexes for Highly Controlled ATRP: Influence of Backbone Substitution on Redox Chemistry and Solubility.” <i>European Journal of Inorganic Chemistry</i> 2018, no. 27 (2018): 3164–75. <a href=\"https://doi.org/10.1002/ejic.201800511\">https://doi.org/10.1002/ejic.201800511</a>."},"page":"3164-3175","intvolume":"      2018","project":[{"_id":"52","name":"Computing Resources Provided by the Paderborn Center for Parallel Computing"}],"_id":"13186","user_id":"40778","keyword":["Copper","Polymerization","Redox chemistry","Structure elucidation","Ligand effects"],"language":[{"iso":"eng"}],"type":"journal_article","publication":"European Journal of Inorganic Chemistry","abstract":[{"text":"Ligands DMEG6etqu, TMG6etqu, DMEG6buqu, and TMG6buqu were developed on the basis of guanidine quinoline (GUAqu) ligands 1,3-dimethyl-N-(quinolin-8-yl)imidazolidin-2-imine (DMEGqu) and 1,1,3,3-tetramethyl-2-(quinolin-8-yl)guanidine (TMGqu). These ligands feature an alkyl substituent at the C6 of the quinoline backbone. The synthetic strategy developed here enables inexpensive syntheses of any kind of C6-substituted GUAqu ligands. On one hand, the alkylation increases the solubility of corresponding copper complexes in apolar atom transfer radical polymerization (ATRP) monomers like styrene. On the other hand, it has a significant electronic influence and thus an effect on the donor properties of the new ligands. Seven CuI and CuII complexes of DMEG6etqu and TMG6etqu have been crystallized and were studied with regard to their structural and electrochemical properties. CuI and CuII complexes of DMEG6buqu and TMG6buqu turned out to be perfectly soluble in pure styrene even at room temperature, which makes them excellent catalysts in the ATRP of apolar monomers. The key characteristics of the ATRP equilibrium, KATRP and kact, were determined for the new complexes. In addition, we used our recently developed DFT methodology, NBO analysis, and isodesmic reactions to predict the influence of the introduced alkyl substituents. It turned out that high conformational freedom in the complex structures leads to a significant uncertainty in prediction of the thermodynamic properties.","lang":"eng"}],"status":"public"},{"type":"journal_article","publication":"International Journal of Pharmaceutics","status":"public","_id":"30935","user_id":"94","department":[{"_id":"311"}],"keyword":["NanoparticlesLight-responsive polymersPhotodynamic therapyPoly(lactic-co-glycolic acid)Intestinal cancer"],"language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["0378-5173"]},"year":"2018","citation":{"chicago":"Anderski, Juliane, Laura Mahlert, Jingjiang Sun, Wolfgang Birnbaum, Dennis Mulac, Sebastian Schreiber, Fabian Herrmann, Dirk Kuckling, and Klaus Langer. “Light-Responsive Nanoparticles Based on New Polycarbonate Polymers as Innovative Drug Delivery Systems for Photosensitizers in PDT.” <i>International Journal of Pharmaceutics</i> 557 (2018): 182–91. <a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">https://doi.org/10.1016/j.ijpharm.2018.12.040</a>.","ieee":"J. Anderski <i>et al.</i>, “Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT,” <i>International Journal of Pharmaceutics</i>, vol. 557, pp. 182–191, 2018, doi: <a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">10.1016/j.ijpharm.2018.12.040</a>.","ama":"Anderski J, Mahlert L, Sun J, et al. Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT. <i>International Journal of Pharmaceutics</i>. 2018;557:182-191. doi:<a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">10.1016/j.ijpharm.2018.12.040</a>","short":"J. Anderski, L. Mahlert, J. Sun, W. Birnbaum, D. Mulac, S. Schreiber, F. Herrmann, D. Kuckling, K. Langer, International Journal of Pharmaceutics 557 (2018) 182–191.","bibtex":"@article{Anderski_Mahlert_Sun_Birnbaum_Mulac_Schreiber_Herrmann_Kuckling_Langer_2018, title={Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT}, volume={557}, DOI={<a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">10.1016/j.ijpharm.2018.12.040</a>}, journal={International Journal of Pharmaceutics}, publisher={Elsevier BV}, author={Anderski, Juliane and Mahlert, Laura and Sun, Jingjiang and Birnbaum, Wolfgang and Mulac, Dennis and Schreiber, Sebastian and Herrmann, Fabian and Kuckling, Dirk and Langer, Klaus}, year={2018}, pages={182–191} }","mla":"Anderski, Juliane, et al. “Light-Responsive Nanoparticles Based on New Polycarbonate Polymers as Innovative Drug Delivery Systems for Photosensitizers in PDT.” <i>International Journal of Pharmaceutics</i>, vol. 557, Elsevier BV, 2018, pp. 182–91, doi:<a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">10.1016/j.ijpharm.2018.12.040</a>.","apa":"Anderski, J., Mahlert, L., Sun, J., Birnbaum, W., Mulac, D., Schreiber, S., Herrmann, F., Kuckling, D., &#38; Langer, K. (2018). Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT. <i>International Journal of Pharmaceutics</i>, <i>557</i>, 182–191. <a href=\"https://doi.org/10.1016/j.ijpharm.2018.12.040\">https://doi.org/10.1016/j.ijpharm.2018.12.040</a>"},"intvolume":"       557","page":"182-191","date_updated":"2022-04-21T09:14:49Z","publisher":"Elsevier BV","date_created":"2022-04-21T09:13:47Z","author":[{"full_name":"Anderski, Juliane","last_name":"Anderski","first_name":"Juliane"},{"first_name":"Laura","last_name":"Mahlert","full_name":"Mahlert, Laura"},{"first_name":"Jingjiang","full_name":"Sun, Jingjiang","last_name":"Sun"},{"last_name":"Birnbaum","full_name":"Birnbaum, Wolfgang","first_name":"Wolfgang"},{"last_name":"Mulac","full_name":"Mulac, Dennis","first_name":"Dennis"},{"last_name":"Schreiber","full_name":"Schreiber, Sebastian","first_name":"Sebastian"},{"first_name":"Fabian","last_name":"Herrmann","full_name":"Herrmann, Fabian"},{"id":"287","full_name":"Kuckling, Dirk","last_name":"Kuckling","first_name":"Dirk"},{"first_name":"Klaus","full_name":"Langer, Klaus","last_name":"Langer"}],"volume":557,"title":"Light-responsive nanoparticles based on new polycarbonate polymers as innovative drug delivery systems for photosensitizers in PDT","doi":"10.1016/j.ijpharm.2018.12.040"}]