---
_id: '45828'
abstract:
- lang: eng
  text: <jats:p>This article presents the potential-dependent adsorption of two proteins,
    bovine serum albumin (BSA) and lysozyme (LYZ), on Ti6Al4V alloy at pH 7.4 and
    37 °C. The adsorption process was studied on an electropolished alloy under cathodic
    and anodic overpotentials, compared to the open circuit potential (OCP). To analyze
    the adsorption process, various complementary interface analytical techniques
    were employed, including PM-IRRAS (polarization-modulation infrared reflection-absorption
    spectroscopy), AFM (atomic force microscopy), XPS (X-ray photoelectron spectroscopy),
    and E-QCM (electrochemical quartz crystal microbalance) measurements. The polarization
    experiments were conducted within a potential range where charging of the electric
    double layer dominates, and Faradaic currents can be disregarded. The findings
    highlight the significant influence of the interfacial charge distribution on
    the adsorption of BSA and LYZ onto the alloy surface. Furthermore, electrochemical
    analysis of the protein layers formed under applied overpotentials demonstrated
    improved corrosion protection properties. These studies provide valuable insights
    into protein adsorption on titanium alloys under physiological conditions, characterized
    by varying potentials of the passive alloy.</jats:p>
author:
- first_name: Belma
  full_name: Duderija, Belma
  id: '54863'
  last_name: Duderija
- first_name: Alejandro
  full_name: González-Orive, Alejandro
  last_name: González-Orive
- first_name: Christoph
  full_name: Ebbert, Christoph
  id: '7266'
  last_name: Ebbert
- first_name: Vanessa
  full_name: Neßlinger, Vanessa
  last_name: Neßlinger
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
citation:
  ama: Duderija B, González-Orive A, Ebbert C, Neßlinger V, Keller A, Grundmeier G.
    Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy.
    <i>Molecules</i>. 2023;28(13):5109. doi:<a href="https://doi.org/10.3390/molecules28135109">10.3390/molecules28135109</a>
  apa: Duderija, B., González-Orive, A., Ebbert, C., Neßlinger, V., Keller, A., &#38;
    Grundmeier, G. (2023). Electrode Potential-Dependent Studies of Protein Adsorption
    on Ti6Al4V Alloy. <i>Molecules</i>, <i>28</i>(13), 5109. <a href="https://doi.org/10.3390/molecules28135109">https://doi.org/10.3390/molecules28135109</a>
  bibtex: '@article{Duderija_González-Orive_Ebbert_Neßlinger_Keller_Grundmeier_2023,
    title={Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
    Alloy}, volume={28}, DOI={<a href="https://doi.org/10.3390/molecules28135109">10.3390/molecules28135109</a>},
    number={13}, journal={Molecules}, publisher={MDPI AG}, author={Duderija, Belma
    and González-Orive, Alejandro and Ebbert, Christoph and Neßlinger, Vanessa and
    Keller, Adrian and Grundmeier, Guido}, year={2023}, pages={5109} }'
  chicago: 'Duderija, Belma, Alejandro González-Orive, Christoph Ebbert, Vanessa Neßlinger,
    Adrian Keller, and Guido Grundmeier. “Electrode Potential-Dependent Studies of
    Protein Adsorption on Ti6Al4V Alloy.” <i>Molecules</i> 28, no. 13 (2023): 5109.
    <a href="https://doi.org/10.3390/molecules28135109">https://doi.org/10.3390/molecules28135109</a>.'
  ieee: 'B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, and G.
    Grundmeier, “Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V
    Alloy,” <i>Molecules</i>, vol. 28, no. 13, p. 5109, 2023, doi: <a href="https://doi.org/10.3390/molecules28135109">10.3390/molecules28135109</a>.'
  mla: Duderija, Belma, et al. “Electrode Potential-Dependent Studies of Protein Adsorption
    on Ti6Al4V Alloy.” <i>Molecules</i>, vol. 28, no. 13, MDPI AG, 2023, p. 5109,
    doi:<a href="https://doi.org/10.3390/molecules28135109">10.3390/molecules28135109</a>.
  short: B. Duderija, A. González-Orive, C. Ebbert, V. Neßlinger, A. Keller, G. Grundmeier,
    Molecules 28 (2023) 5109.
date_created: 2023-07-03T08:06:28Z
date_updated: 2023-07-03T08:07:55Z
department:
- _id: '302'
doi: 10.3390/molecules28135109
intvolume: '        28'
issue: '13'
keyword:
- Chemistry (miscellaneous)
- Analytical Chemistry
- Organic Chemistry
- Physical and Theoretical Chemistry
- Molecular Medicine
- Drug Discovery
- Pharmaceutical Science
language:
- iso: eng
page: '5109'
publication: Molecules
publication_identifier:
  issn:
  - 1420-3049
publication_status: published
publisher: MDPI AG
status: public
title: Electrode Potential-Dependent Studies of Protein Adsorption on Ti6Al4V Alloy
type: journal_article
user_id: '48864'
volume: 28
year: '2023'
...
---
_id: '22657'
author:
- first_name: Roozbeh
  full_name: Hajiraissi, Roozbeh
  last_name: Hajiraissi
- first_name: Marcel
  full_name: Hanke, Marcel
  last_name: Hanke
- first_name: Alejandro
  full_name: Gonzalez Orive, Alejandro
  last_name: Gonzalez Orive
- first_name: Belma
  full_name: Duderija, Belma
  id: '54863'
  last_name: Duderija
- first_name: Ulrike
  full_name: Hofmann, Ulrike
  last_name: Hofmann
- first_name: Yixin
  full_name: Zhang, Yixin
  last_name: Zhang
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Hajiraissi R, Hanke M, Gonzalez Orive A, et al. Effect of Terminal Modifications
    on the Adsorption and Assembly of hIAPP(20–29). <i>ACS Omega</i>. 2019;4:2649-2660.
    doi:<a href="https://doi.org/10.1021/acsomega.8b03028">10.1021/acsomega.8b03028</a>
  apa: Hajiraissi, R., Hanke, M., Gonzalez Orive, A., Duderija, B., Hofmann, U., Zhang,
    Y., … Keller, A. (2019). Effect of Terminal Modifications on the Adsorption and
    Assembly of hIAPP(20–29). <i>ACS Omega</i>, <i>4</i>, 2649–2660. <a href="https://doi.org/10.1021/acsomega.8b03028">https://doi.org/10.1021/acsomega.8b03028</a>
  bibtex: '@article{Hajiraissi_Hanke_Gonzalez Orive_Duderija_Hofmann_Zhang_Grundmeier_Keller_2019,
    title={Effect of Terminal Modifications on the Adsorption and Assembly of hIAPP(20–29)},
    volume={4}, DOI={<a href="https://doi.org/10.1021/acsomega.8b03028">10.1021/acsomega.8b03028</a>},
    journal={ACS Omega}, author={Hajiraissi, Roozbeh and Hanke, Marcel and Gonzalez
    Orive, Alejandro and Duderija, Belma and Hofmann, Ulrike and Zhang, Yixin and
    Grundmeier, Guido and Keller, Adrian}, year={2019}, pages={2649–2660} }'
  chicago: 'Hajiraissi, Roozbeh, Marcel Hanke, Alejandro Gonzalez Orive, Belma Duderija,
    Ulrike Hofmann, Yixin Zhang, Guido Grundmeier, and Adrian Keller. “Effect of Terminal
    Modifications on the Adsorption and Assembly of HIAPP(20–29).” <i>ACS Omega</i>
    4 (2019): 2649–60. <a href="https://doi.org/10.1021/acsomega.8b03028">https://doi.org/10.1021/acsomega.8b03028</a>.'
  ieee: R. Hajiraissi <i>et al.</i>, “Effect of Terminal Modifications on the Adsorption
    and Assembly of hIAPP(20–29),” <i>ACS Omega</i>, vol. 4, pp. 2649–2660, 2019.
  mla: Hajiraissi, Roozbeh, et al. “Effect of Terminal Modifications on the Adsorption
    and Assembly of HIAPP(20–29).” <i>ACS Omega</i>, vol. 4, 2019, pp. 2649–60, doi:<a
    href="https://doi.org/10.1021/acsomega.8b03028">10.1021/acsomega.8b03028</a>.
  short: R. Hajiraissi, M. Hanke, A. Gonzalez Orive, B. Duderija, U. Hofmann, Y. Zhang,
    G. Grundmeier, A. Keller, ACS Omega 4 (2019) 2649–2660.
date_created: 2021-07-08T12:16:52Z
date_updated: 2022-01-06T06:55:38Z
department:
- _id: '302'
doi: 10.1021/acsomega.8b03028
intvolume: '         4'
language:
- iso: eng
page: 2649-2660
publication: ACS Omega
publication_identifier:
  issn:
  - 2470-1343
  - 2470-1343
publication_status: published
status: public
title: Effect of Terminal Modifications on the Adsorption and Assembly of hIAPP(20–29)
type: journal_article
user_id: '48864'
volume: 4
year: '2019'
...
---
_id: '22541'
abstract:
- lang: eng
  text: Monodisperse micron-sized silica particle monolayers deposited onto plasma-grown
    SiOx-ultra-thin films have been used as reference systems to investigate wetting,
    water adsorption and capillary bridge formation as a function of silica surface
    functionalization. 1H,1H, 2H,2H perfluorooctyltriethoxysil (FOTS) monolayers,
    have been deposited on the respective surfaces by means of chemical vapor deposition
    resulting in macroscopically low energy surfaces. X-ray photoelectron spectroscopy
    (XPS) and Fourier transform infrared (FTIR) reflection absorption spectroscopy
    confirmed the monolayer formation. Water adsorption isotherms were studied by
    a combination of in-situ FTIR reflection spectroscopy and quartz crystal microbalance
    (QCM) while macroscopic wetting was analysed by contact angle measurements. The
    comparative data evaluation indicates that the macroscopic wetting behaviour was
    changed as expected, however, that water nanodroplets formed both at intrinsic
    defects of the FOTS monolayer and at the FOTS/SiOx interface. Capillary bridges
    of liquid water are dominantly formed in the confined particle contact areas and
    between surface asperities on the particles. The comparison of wetting, adsorption
    and capillary bridge formation shows that the hydrophobization of porous materials
    by organosilane monolayers leads to the formation of morphology dependent nanoscopic
    defects that act as sites for preferential capillary bridge formation.
author:
- first_name: Ignacio
  full_name: Giner, Ignacio
  last_name: Giner
- first_name: Boray
  full_name: Torun, Boray
  last_name: Torun
- first_name: Yan
  full_name: Han, Yan
  last_name: Han
- first_name: Belma
  full_name: Duderija, Belma
  id: '54863'
  last_name: Duderija
- first_name: Dennis
  full_name: Meinderink, Dennis
  last_name: Meinderink
- first_name: Alejandro González
  full_name: Orive, Alejandro González
  last_name: Orive
- first_name: Maria Teresa
  full_name: de los Arcos de Pedro, Maria Teresa
  id: '54556'
  last_name: de los Arcos de Pedro
- first_name: Christian
  full_name: Weinberger, Christian
  last_name: Weinberger
- first_name: Michael
  full_name: Tiemann, Michael
  id: '23547'
  last_name: Tiemann
  orcid: 0000-0003-1711-2722
- first_name: Hans-Joachim
  full_name: Schmid, Hans-Joachim
  id: '464'
  last_name: Schmid
  orcid: 000-0001-8590-1921
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
citation:
  ama: Giner I, Torun B, Han Y, et al. Water adsorption and capillary bridge formation
    on silica micro-particle layers modified with perfluorinated organosilane monolayers.
    <i>Applied Surface Science</i>. Published online 2019:873-879. doi:<a href="https://doi.org/10.1016/j.apsusc.2018.12.221">10.1016/j.apsusc.2018.12.221</a>
  apa: Giner, I., Torun, B., Han, Y., Duderija, B., Meinderink, D., Orive, A. G.,
    de los Arcos de Pedro, M. T., Weinberger, C., Tiemann, M., Schmid, H.-J., &#38;
    Grundmeier, G. (2019). Water adsorption and capillary bridge formation on silica
    micro-particle layers modified with perfluorinated organosilane monolayers. <i>Applied
    Surface Science</i>, 873–879. <a href="https://doi.org/10.1016/j.apsusc.2018.12.221">https://doi.org/10.1016/j.apsusc.2018.12.221</a>
  bibtex: '@article{Giner_Torun_Han_Duderija_Meinderink_Orive_de los Arcos de Pedro_Weinberger_Tiemann_Schmid_et
    al._2019, title={Water adsorption and capillary bridge formation on silica micro-particle
    layers modified with perfluorinated organosilane monolayers}, DOI={<a href="https://doi.org/10.1016/j.apsusc.2018.12.221">10.1016/j.apsusc.2018.12.221</a>},
    journal={Applied Surface Science}, author={Giner, Ignacio and Torun, Boray and
    Han, Yan and Duderija, Belma and Meinderink, Dennis and Orive, Alejandro González
    and de los Arcos de Pedro, Maria Teresa and Weinberger, Christian and Tiemann,
    Michael and Schmid, Hans-Joachim and et al.}, year={2019}, pages={873–879} }'
  chicago: Giner, Ignacio, Boray Torun, Yan Han, Belma Duderija, Dennis Meinderink,
    Alejandro González Orive, Maria Teresa de los Arcos de Pedro, et al. “Water Adsorption
    and Capillary Bridge Formation on Silica Micro-Particle Layers Modified with Perfluorinated
    Organosilane Monolayers.” <i>Applied Surface Science</i>, 2019, 873–79. <a href="https://doi.org/10.1016/j.apsusc.2018.12.221">https://doi.org/10.1016/j.apsusc.2018.12.221</a>.
  ieee: 'I. Giner <i>et al.</i>, “Water adsorption and capillary bridge formation
    on silica micro-particle layers modified with perfluorinated organosilane monolayers,”
    <i>Applied Surface Science</i>, pp. 873–879, 2019, doi: <a href="https://doi.org/10.1016/j.apsusc.2018.12.221">10.1016/j.apsusc.2018.12.221</a>.'
  mla: Giner, Ignacio, et al. “Water Adsorption and Capillary Bridge Formation on
    Silica Micro-Particle Layers Modified with Perfluorinated Organosilane Monolayers.”
    <i>Applied Surface Science</i>, 2019, pp. 873–79, doi:<a href="https://doi.org/10.1016/j.apsusc.2018.12.221">10.1016/j.apsusc.2018.12.221</a>.
  short: I. Giner, B. Torun, Y. Han, B. Duderija, D. Meinderink, A.G. Orive, M.T.
    de los Arcos de Pedro, C. Weinberger, M. Tiemann, H.-J. Schmid, G. Grundmeier,
    Applied Surface Science (2019) 873–879.
date_created: 2021-07-07T08:40:38Z
date_updated: 2023-07-12T07:58:00Z
department:
- _id: '302'
doi: 10.1016/j.apsusc.2018.12.221
language:
- iso: eng
page: 873-879
publication: Applied Surface Science
publication_identifier:
  issn:
  - 0169-4332
publication_status: published
status: public
title: Water adsorption and capillary bridge formation on silica micro-particle layers
  modified with perfluorinated organosilane monolayers
type: journal_article
user_id: '54863'
year: '2019'
...
---
_id: '22667'
author:
- first_name: Roozbeh
  full_name: Hajiraissi, Roozbeh
  last_name: Hajiraissi
- first_name: Marcel
  full_name: Hanke, Marcel
  last_name: Hanke
- first_name: Yu
  full_name: Yang, Yu
  last_name: Yang
- first_name: Belma
  full_name: Duderija, Belma
  id: '54863'
  last_name: Duderija
- first_name: Alejandro
  full_name: Gonzalez Orive, Alejandro
  last_name: Gonzalez Orive
- first_name: Guido
  full_name: Grundmeier, Guido
  id: '194'
  last_name: Grundmeier
- first_name: Adrian
  full_name: Keller, Adrian
  id: '48864'
  last_name: Keller
  orcid: 0000-0001-7139-3110
citation:
  ama: Hajiraissi R, Hanke M, Yang Y, et al. Adsorption and Fibrillization of Islet
    Amyloid Polypeptide at Self-Assembled Monolayers Studied by QCM-D, AFM, and PM-IRRAS.
    <i>Langmuir</i>. 2018;34:3517-3524. doi:<a href="https://doi.org/10.1021/acs.langmuir.7b03626">10.1021/acs.langmuir.7b03626</a>
  apa: Hajiraissi, R., Hanke, M., Yang, Y., Duderija, B., Gonzalez Orive, A., Grundmeier,
    G., &#38; Keller, A. (2018). Adsorption and Fibrillization of Islet Amyloid Polypeptide
    at Self-Assembled Monolayers Studied by QCM-D, AFM, and PM-IRRAS. <i>Langmuir</i>,
    <i>34</i>, 3517–3524. <a href="https://doi.org/10.1021/acs.langmuir.7b03626">https://doi.org/10.1021/acs.langmuir.7b03626</a>
  bibtex: '@article{Hajiraissi_Hanke_Yang_Duderija_Gonzalez Orive_Grundmeier_Keller_2018,
    title={Adsorption and Fibrillization of Islet Amyloid Polypeptide at Self-Assembled
    Monolayers Studied by QCM-D, AFM, and PM-IRRAS}, volume={34}, DOI={<a href="https://doi.org/10.1021/acs.langmuir.7b03626">10.1021/acs.langmuir.7b03626</a>},
    journal={Langmuir}, author={Hajiraissi, Roozbeh and Hanke, Marcel and Yang, Yu
    and Duderija, Belma and Gonzalez Orive, Alejandro and Grundmeier, Guido and Keller,
    Adrian}, year={2018}, pages={3517–3524} }'
  chicago: 'Hajiraissi, Roozbeh, Marcel Hanke, Yu Yang, Belma Duderija, Alejandro
    Gonzalez Orive, Guido Grundmeier, and Adrian Keller. “Adsorption and Fibrillization
    of Islet Amyloid Polypeptide at Self-Assembled Monolayers Studied by QCM-D, AFM,
    and PM-IRRAS.” <i>Langmuir</i> 34 (2018): 3517–24. <a href="https://doi.org/10.1021/acs.langmuir.7b03626">https://doi.org/10.1021/acs.langmuir.7b03626</a>.'
  ieee: R. Hajiraissi <i>et al.</i>, “Adsorption and Fibrillization of Islet Amyloid
    Polypeptide at Self-Assembled Monolayers Studied by QCM-D, AFM, and PM-IRRAS,”
    <i>Langmuir</i>, vol. 34, pp. 3517–3524, 2018.
  mla: Hajiraissi, Roozbeh, et al. “Adsorption and Fibrillization of Islet Amyloid
    Polypeptide at Self-Assembled Monolayers Studied by QCM-D, AFM, and PM-IRRAS.”
    <i>Langmuir</i>, vol. 34, 2018, pp. 3517–24, doi:<a href="https://doi.org/10.1021/acs.langmuir.7b03626">10.1021/acs.langmuir.7b03626</a>.
  short: R. Hajiraissi, M. Hanke, Y. Yang, B. Duderija, A. Gonzalez Orive, G. Grundmeier,
    A. Keller, Langmuir 34 (2018) 3517–3524.
date_created: 2021-07-08T12:36:59Z
date_updated: 2022-01-06T06:55:38Z
department:
- _id: '302'
doi: 10.1021/acs.langmuir.7b03626
intvolume: '        34'
language:
- iso: eng
page: 3517-3524
publication: Langmuir
publication_identifier:
  issn:
  - 0743-7463
  - 1520-5827
publication_status: published
status: public
title: Adsorption and Fibrillization of Islet Amyloid Polypeptide at Self-Assembled
  Monolayers Studied by QCM-D, AFM, and PM-IRRAS
type: journal_article
user_id: '48864'
volume: 34
year: '2018'
...