@article{60182, author = {{Perrar, I and Hohoff, E and Lesani, A and Schmitting, S and Libuda, Lars and Krüger, Bettina and Stutz, Bianca and Nöthlings, U and Buyken, Anette and Alexy, U and Jankovic, N}}, issn = {{1436-6207}}, journal = {{Eur J Nutr}}, number = {{4}}, pages = {{165}}, title = {{{Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study.}}}, volume = {{64}}, year = {{2025}}, } @article{60873, abstract = {{Abstract Variations in circadian rhythm-related genes influence the individual chronotype. Here, we hypothesize that the peak of clock gene expression at 7 a.m. differs between young adults with a late chronotype and young adults with an early chronotype. Participants of the Chronotype and Nutrition nutritional trial (ChroNu study) were selected for their chronotype assessed by the Munich Chronotype questionnaire (MCTQ) and actigraphy. Total RNA was isolated from CD14+ monocytes of participants at 7 a.m. on the run-in day. Expression levels of seven clock genes (PER1, PER2, PER3, NR1D1, NR1D2, CRY1 and CRISPLD2) of individuals with early (n = 11) or late chronotypes (n = 19) were analysed by reverse transcription quantitative polymerase chain reaction. Difference in expression levels was tested by Mann Whitney-U test. The relative expression levels of the selected genes were not significantly different between individuals with early and late chronotypes (all p > 0.07). Contrary to expectation, clock gene expression levels at 7 a.m. was similar in individuals with early and late chronotypes. Further studies on larger sample sizes with multiple sampling time points should elucidate whether gene expression is altered at other day times underscoring the biological difference between individuals with early or late chronotypes.}}, author = {{Krueger, Bettina and Rajcsanyi, Luisa Sophie and Hundertmark, Katharina and Stutz, Bianca and Hinney, Anke and Buyken, Anette E.}}, issn = {{2045-2322}}, journal = {{Scientific Reports}}, number = {{1}}, publisher = {{Springer Science and Business Media LLC}}, title = {{{Morning clock gene expression in young adults of early and late chronotypes}}}, doi = {{10.1038/s41598-025-12423-7}}, volume = {{15}}, year = {{2025}}, } @article{54926, author = {{Stutz, Bianca and Krueger, Bettina and Goletzke, Janina and Jankovic, Nicole and Alexy, Ute and Herder, Christian and Dierkes, Jutta and Berg-Beckhoff, Gabriele and Jakobsmeyer, Rasmus and Reinsberger, Claus and Buyken, Anette E.}}, issn = {{1436-6215}}, journal = {{European Journal of Nutrition}}, publisher = {{Springer}}, title = {{{Glycemic response to meals with a high glycemic index differs between morning and evening: a randomized cross-over controlled trial among students with early or late chronotype}}}, doi = {{10.1007/s00394-024-03372-4}}, year = {{2024}}, } @article{54927, author = {{Stutz, Bianca and Goletzke, Janina and Krueger, Bettina and Jankovic, Nicole and Alexy, Ute and Herder, Christian and Jakobsmeyer, Rasmus and Reinsberger, Claus and Buyken, Anette E.}}, journal = {{Appetite}}, pages = {{107569}}, publisher = {{Elsevier}}, title = {{{Association between glucose dips and the feeling of hunger in a dietary intervention study among students with early and late chronotype-secondary analysis of a randomized cross-over nutrition trial}}}, doi = {{10.1016/j.appet.2024.107569}}, volume = {{200}}, year = {{2024}}, } @article{57429, author = {{Krueger, Bettina and Stutz, Bianca and Jakobsmeyer, Rasmus and Reinsberger, Claus and Buyken, Anette E.}}, issn = {{0742-0528}}, journal = {{Chronobiology International}}, pages = {{1--10}}, publisher = {{Informa UK Limited}}, title = {{{Relevance of high glycaemic index breakfast for heart rate variability among collegiate students with early and late chronotypes}}}, doi = {{10.1080/07420528.2024.2428203}}, year = {{2024}}, } @article{48456, abstract = {{Abstract Purpose Our aim was to assess alignment in timing of ‘highest caloric intake’ with individual chronotype and its association with body composition in adolescents. Methods We used repeatedly collected data from n = 196 adolescents (age 9–16 years, providing N = 401 yearly questionnaires) of the DONALD open cohort study. Chronotype was assessed by the Munich Chronotype Questionnaire from which midpoint of sleep (MSFsc) was derived. A sex- and age-specific diet-chrono-alignment score (DCAS) was calculated as the difference in hours between the chronotype-specific median timing of highest caloric intake of the studied population and the individual timing of ‘highest caloric intake’ or vice versa. Repeated-measures regression models were applied to study cross-sectional and longitudinal associations between the DCAS and body composition, e.g., Fat Mass Index (FMI) or Fat Free Mass Index (FFMI). Results DCAS ranged from −6:42 h to + 8:01 h and was not associated with body composition. Among adolescents with a later chronotype (N = 201) a 1 h increase in DCAS (later consumption of ‘highest caloric intake’ in comparison to the median intake of that group), increased FFMI by 1.92 kg/m2 (95% CI: 0.15, 3.69, p value = 0.04) over a median follow-up of 0.94 year. Conclusion Alignment of energy intake with individual chronotype appears beneficial for FFMI among those with a late chronotype. }}, author = {{Jankovic, Nicole and Schmitting, Sarah and Stutz, Bianca and Krüger, Bettina and Buyken, Anette and Alexy, Ute}}, issn = {{1436-6207}}, journal = {{European Journal of Nutrition}}, keywords = {{Nutrition and Dietetics, Medicine (miscellaneous)}}, publisher = {{Springer Science and Business Media LLC}}, title = {{{Alignment between timing of ‘highest caloric intake’ and chronotype in relation to body composition during adolescence: the DONALD Study}}}, doi = {{10.1007/s00394-023-03259-w}}, year = {{2023}}, } @article{36505, abstract = {{Young adults with a later chronotype are vulnerable for a discrepancy in sleep rhythm between work- and free days, called social jet lag (SJL). This study analysed (i) chronotype/SJL association with visceral fat/skeletal muscle mass, (ii) the attribution to physical activity behaviour, and (iii) chronotype-specific changes in physical activity behaviour in young adults during the Covid-19 pandemic lockdown. Chronotype and SJL were derived from the Munich-Chrono-Type-Questionnaire in 320 German students (age 18–25 years) from September 2019 to January 2020, 156 of these participated in an online follow-up survey in June 2020. Body composition was assessed by bioimpedance analysis at baseline. Multivariable linear regression analyses were used to relate chronotype/SJL to body composition; the contribution of self-reported physical activity was tested by mediation analysis. At baseline, a later chronotype and a larger SJL were associated with a higher visceral fat mass (P<0.05), this relation was notably mediated by the attention to physical activity (P<0.05). Chronotype (P = 0.02) but not SJL (P = 0.87) was inversely associated with skeletal muscle mass. During the pandemic lockdown, chronotype hardly changed, but SJL was reduced. Timing and physical activity behaviour remained in most participants and changes were unrelated to chronotype (all P>0.07). A later chronotype/higher SJL may increase the risk of a higher visceral fat mass even in this relatively healthy sample, which may be partly due to their physical activity behaviour. Despite a reduction in SJL during the pandemic lockdown, later chronotypes did not change their physical activity behaviour more than earlier chronotypes.}}, author = {{Krueger, Betina and Stutz, Bianca and Jankovic, Nicole and Alexy, Ute and Kilanowski, Anna and Libuda, Lars and Buyken, Anette E.}}, issn = {{1932-6203}}, journal = {{PLOS ONE}}, keywords = {{Multidisciplinary}}, number = {{1}}, publisher = {{Public Library of Science (PLoS)}}, title = {{{The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown}}}, doi = {{10.1371/journal.pone.0279620}}, volume = {{18}}, year = {{2023}}, } @article{35754, author = {{Stutz, Bianca and Buyken, Anette and Schadow, A.M. and Jankovic, N. and Alexy, U. and Krueger, B.}}, issn = {{0195-6663}}, journal = {{Appetite}}, keywords = {{Nutrition and Dietetics, General Psychology}}, publisher = {{Elsevier BV}}, title = {{{Associations of chronotype and social jetlag with eating jetlag and their changes among German students during the first COVID-19 lockdown. The Chronotype and Nutrition study}}}, doi = {{10.1016/j.appet.2022.106333}}, volume = {{180}}, year = {{2022}}, } @article{35310, author = {{Goletzke, J and Weber, KS and Kössler, T and Zaharia, OP and Bódis, K and Müssig, K and Szendroedi, J and Burkart, V and Stutz, Bianca and Nöthlings, U and Buyken, Anette and Roden, M and Group, GDS}}, issn = {{0939-4753}}, journal = {{Nutr Metab Cardiovasc Dis}}, number = {{10}}, pages = {{2310--2320}}, title = {{{Relative validity of a glycemic index extended food-frequency questionnaire.}}}, volume = {{32}}, year = {{2022}}, } @article{43015, author = {{Stutz, Bianca and Ahola, A.J. and Harjutsalo, V. and Forsblom, C. and Groop, P.-H.}}, issn = {{0939-4753}}, journal = {{Nutrition, Metabolism and Cardiovascular Diseases}}, keywords = {{Cardiology and Cardiovascular Medicine, Nutrition and Dietetics, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous)}}, number = {{5}}, pages = {{470--476}}, publisher = {{Elsevier BV}}, title = {{{Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes}}}, doi = {{10.1016/j.numecd.2018.01.011}}, volume = {{28}}, year = {{2018}}, }