--- _id: '65375' abstract: - lang: eng text: "Abstract\r\n Vitamin D has been associated with depression, potentially via anti-inflammatory mechanisms, yet data is scarce, particularly in adolescence. We investigated (1) whether lower vitamin D status is associated with greater depression severity and (2) whether this association is statistically moderated by inflammation in patients of a child and adolescent psychiatry department. At admission fasting morning venous blood was drawn. Serum vitamin D (25(OH)D) and C-reactive protein (CRP) were analyzed in all participants [n=465 (64.7%♀; 11.3-18.9 years)]. In a subsample [n=177], we additionally measured tumor necrosis factor-alpha, interferon-gamma and interleukin (IL)-1β, IL-6, IL-8, IL-10. Depression severity was assessed by the Beck Depression Inventory-II (BDI-II) [n=450], the Diagnostic System for Mental Disorders in Childhood and Adolescence via self-assessment (DISYPS Self) [n=441], and parent-assessment (DISYPS Proxy) [n=422]. Overall, 43.2% [n=201] were at risk for vitamin D deficiency (<30nmol/L), and 73.5%-83.2% –depending on assessment tool– showed at least mild depression. Linear regression revealed an inverse association between 25(OH)D and BDI-II in both crude and CRP-adjusted full-sample models. Logistic regressions showed a robust inverse association between 25(OH)D and DISYPS Proxy, but not for DISYPS Self. Although 25(OH)D was inversely correlated with some pro-inflammatory markers, neither their inclusion in regression models nor formal mediation analyses supported inflammation as a mediator of the vitamin D–depression association. Overall, our results suggest that vitamin D relates modestly to both depression and inflammation in adolescence. However, based on the measured parameters, we cannot confirm that anti-inflammatory effects are the link between vitamin D and depression." author: - first_name: Laura full_name: Schlarbaum, Laura id: '96697' last_name: Schlarbaum - first_name: Nicole full_name: Jankovic, Nicole id: '105192' last_name: Jankovic orcid: https://orcid.org/0000-0002-9235-5356 - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Harald full_name: Engler, Harald last_name: Engler - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: Schlarbaum L, Jankovic N, Bühlmeier J, et al. Does inflammation explain the association between vitamin D and depression? Results of a cross-sectional study in children and adolescents. British Journal of Nutrition. Published online 2026:1-37. doi:10.1017/s0007114526106928 apa: Schlarbaum, L., Jankovic, N., Bühlmeier, J., Engler, H., Hirtz, R., Grasemann, C., Peters, T., Hinney, A., Antel, J., Hebebrand, J., Föcker, M., & Libuda, L. (2026). Does inflammation explain the association between vitamin D and depression? Results of a cross-sectional study in children and adolescents. British Journal of Nutrition, 1–37. https://doi.org/10.1017/s0007114526106928 bibtex: '@article{Schlarbaum_Jankovic_Bühlmeier_Engler_Hirtz_Grasemann_Peters_Hinney_Antel_Hebebrand_et al._2026, title={Does inflammation explain the association between vitamin D and depression? Results of a cross-sectional study in children and adolescents}, DOI={10.1017/s0007114526106928}, journal={British Journal of Nutrition}, publisher={Cambridge University Press (CUP)}, author={Schlarbaum, Laura and Jankovic, Nicole and Bühlmeier, Judith and Engler, Harald and Hirtz, Raphael and Grasemann, Corinna and Peters, Triinu and Hinney, Anke and Antel, Jochen and Hebebrand, Johannes and et al.}, year={2026}, pages={1–37} }' chicago: Schlarbaum, Laura, Nicole Jankovic, Judith Bühlmeier, Harald Engler, Raphael Hirtz, Corinna Grasemann, Triinu Peters, et al. “Does Inflammation Explain the Association between Vitamin D and Depression? Results of a Cross-Sectional Study in Children and Adolescents.” British Journal of Nutrition, 2026, 1–37. https://doi.org/10.1017/s0007114526106928. ieee: 'L. Schlarbaum et al., “Does inflammation explain the association between vitamin D and depression? Results of a cross-sectional study in children and adolescents,” British Journal of Nutrition, pp. 1–37, 2026, doi: 10.1017/s0007114526106928.' mla: Schlarbaum, Laura, et al. “Does Inflammation Explain the Association between Vitamin D and Depression? Results of a Cross-Sectional Study in Children and Adolescents.” British Journal of Nutrition, Cambridge University Press (CUP), 2026, pp. 1–37, doi:10.1017/s0007114526106928. short: L. Schlarbaum, N. Jankovic, J. Bühlmeier, H. Engler, R. Hirtz, C. Grasemann, T. Peters, A. Hinney, J. Antel, J. Hebebrand, M. Föcker, L. Libuda, British Journal of Nutrition (2026) 1–37. date_created: 2026-04-08T09:06:17Z date_updated: 2026-04-15T08:58:03Z doi: 10.1017/s0007114526106928 language: - iso: eng page: 1-37 publication: British Journal of Nutrition publication_identifier: issn: - 0007-1145 - 1475-2662 publication_status: published publisher: Cambridge University Press (CUP) status: public title: Does inflammation explain the association between vitamin D and depression? Results of a cross-sectional study in children and adolescents type: journal_article user_id: '96697' year: '2026' ... --- _id: '65374' article_number: '109' author: - first_name: Laura full_name: Schlarbaum, Laura id: '96697' last_name: Schlarbaum - first_name: Nicole full_name: Jankovic, Nicole id: '105192' last_name: Jankovic orcid: https://orcid.org/0000-0002-9235-5356 - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Eva full_name: Hohoff, Eva last_name: Hohoff - first_name: Rhea full_name: Dankers, Rhea id: '64668' last_name: Dankers - first_name: Harald full_name: Engler, Harald last_name: Engler - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Denise full_name: Zwanziger, Denise last_name: Zwanziger - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: Schlarbaum L, Jankovic N, Bühlmeier J, et al. Does inflammation moderate the effect of vitamin D supplementation on depressive symptoms? Results of an interventional study in children and adolescents. European Journal of Nutrition. 2026;65(3). doi:10.1007/s00394-026-03920-0 apa: Schlarbaum, L., Jankovic, N., Bühlmeier, J., Hohoff, E., Dankers, R., Engler, H., Hirtz, R., Zwanziger, D., Grasemann, C., Peters, T., Hinney, A., Antel, J., Föcker, M., & Libuda, L. (2026). Does inflammation moderate the effect of vitamin D supplementation on depressive symptoms? Results of an interventional study in children and adolescents. European Journal of Nutrition, 65(3), Article 109. https://doi.org/10.1007/s00394-026-03920-0 bibtex: '@article{Schlarbaum_Jankovic_Bühlmeier_Hohoff_Dankers_Engler_Hirtz_Zwanziger_Grasemann_Peters_et al._2026, title={Does inflammation moderate the effect of vitamin D supplementation on depressive symptoms? Results of an interventional study in children and adolescents}, volume={65}, DOI={10.1007/s00394-026-03920-0}, number={3109}, journal={European Journal of Nutrition}, publisher={Springer Science and Business Media LLC}, author={Schlarbaum, Laura and Jankovic, Nicole and Bühlmeier, Judith and Hohoff, Eva and Dankers, Rhea and Engler, Harald and Hirtz, Raphael and Zwanziger, Denise and Grasemann, Corinna and Peters, Triinu and et al.}, year={2026} }' chicago: Schlarbaum, Laura, Nicole Jankovic, Judith Bühlmeier, Eva Hohoff, Rhea Dankers, Harald Engler, Raphael Hirtz, et al. “Does Inflammation Moderate the Effect of Vitamin D Supplementation on Depressive Symptoms? Results of an Interventional Study in Children and Adolescents.” European Journal of Nutrition 65, no. 3 (2026). https://doi.org/10.1007/s00394-026-03920-0. ieee: 'L. Schlarbaum et al., “Does inflammation moderate the effect of vitamin D supplementation on depressive symptoms? Results of an interventional study in children and adolescents,” European Journal of Nutrition, vol. 65, no. 3, Art. no. 109, 2026, doi: 10.1007/s00394-026-03920-0.' mla: Schlarbaum, Laura, et al. “Does Inflammation Moderate the Effect of Vitamin D Supplementation on Depressive Symptoms? Results of an Interventional Study in Children and Adolescents.” European Journal of Nutrition, vol. 65, no. 3, 109, Springer Science and Business Media LLC, 2026, doi:10.1007/s00394-026-03920-0. short: L. Schlarbaum, N. Jankovic, J. Bühlmeier, E. Hohoff, R. Dankers, H. Engler, R. Hirtz, D. Zwanziger, C. Grasemann, T. Peters, A. Hinney, J. Antel, M. Föcker, L. Libuda, European Journal of Nutrition 65 (2026). date_created: 2026-04-08T09:04:52Z date_updated: 2026-04-15T08:57:13Z ddc: - '570' doi: 10.1007/s00394-026-03920-0 file: - access_level: closed content_type: application/pdf creator: laura36 date_created: 2026-04-08T09:15:10Z date_updated: 2026-04-08T09:15:10Z file_id: '65377' file_name: 394_2026_Article_3920.pdf file_size: 939647 relation: main_file success: 1 file_date_updated: 2026-04-08T09:15:10Z has_accepted_license: '1' intvolume: ' 65' issue: '3' language: - iso: eng publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published publisher: Springer Science and Business Media LLC status: public title: Does inflammation moderate the effect of vitamin D supplementation on depressive symptoms? Results of an interventional study in children and adolescents type: journal_article user_id: '96697' volume: 65 year: '2026' ... --- _id: '60182' author: - first_name: I full_name: Perrar, I last_name: Perrar - first_name: E full_name: Hohoff, E last_name: Hohoff - first_name: A full_name: Lesani, A last_name: Lesani - first_name: S full_name: Schmitting, S last_name: Schmitting - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Bettina full_name: Krüger, Bettina id: '49428' last_name: Krüger orcid: 0000-0001-5351-1785 - first_name: Bianca full_name: Stutz, Bianca id: '77099' last_name: Stutz - first_name: U full_name: Nöthlings, U last_name: Nöthlings - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: U full_name: Alexy, U last_name: Alexy - first_name: N full_name: Jankovic, N last_name: Jankovic citation: ama: Perrar I, Hohoff E, Lesani A, et al. Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study. Eur J Nutr. 2025;64(4):165. apa: Perrar, I., Hohoff, E., Lesani, A., Schmitting, S., Libuda, L., Krüger, B., Stutz, B., Nöthlings, U., Buyken, A., Alexy, U., & Jankovic, N. (2025). Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study. Eur J Nutr, 64(4), 165. bibtex: '@article{Perrar_Hohoff_Lesani_Schmitting_Libuda_Krüger_Stutz_Nöthlings_Buyken_Alexy_et al._2025, title={Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study.}, volume={64}, number={4}, journal={Eur J Nutr}, author={Perrar, I and Hohoff, E and Lesani, A and Schmitting, S and Libuda, Lars and Krüger, Bettina and Stutz, Bianca and Nöthlings, U and Buyken, Anette and Alexy, U and et al.}, year={2025}, pages={165} }' chicago: 'Perrar, I, E Hohoff, A Lesani, S Schmitting, Lars Libuda, Bettina Krüger, Bianca Stutz, et al. “Circadian Eating Patterns Track from Infancy to Pre- and Primary School-Age, but Are Not Prospectively Associated with Body Composition in Childhood - Results of the DONALD Cohort Study.” Eur J Nutr 64, no. 4 (2025): 165.' ieee: I. Perrar et al., “Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study.,” Eur J Nutr, vol. 64, no. 4, p. 165, 2025. mla: Perrar, I., et al. “Circadian Eating Patterns Track from Infancy to Pre- and Primary School-Age, but Are Not Prospectively Associated with Body Composition in Childhood - Results of the DONALD Cohort Study.” Eur J Nutr, vol. 64, no. 4, 2025, p. 165. short: I. Perrar, E. Hohoff, A. Lesani, S. Schmitting, L. Libuda, B. Krüger, B. Stutz, U. Nöthlings, A. Buyken, U. Alexy, N. Jankovic, Eur J Nutr 64 (2025) 165. date_created: 2025-06-11T08:49:19Z date_updated: 2025-06-11T08:51:28Z department: - _id: '22' external_id: pmid: - '40285866' intvolume: ' 64' issue: '4' language: - iso: eng page: '165' pmid: '1' publication: Eur J Nutr publication_identifier: issn: - 1436-6207 - 1436-6215 status: public title: Circadian eating patterns track from infancy to pre- and primary school-age, but are not prospectively associated with body composition in childhood - Results of the DONALD cohort study. type: journal_article user_id: '92491' volume: 64 year: '2025' ... --- _id: '60471' author: - first_name: N full_name: Knoll-Pientka, N last_name: Knoll-Pientka - first_name: D full_name: Schils, D last_name: Schils - first_name: K full_name: Pasternak, K last_name: Pasternak - first_name: S full_name: Czarnetzky, S last_name: Czarnetzky - first_name: C full_name: Jansen, C last_name: Jansen - first_name: G full_name: Gradl-Dietsch, G last_name: Gradl-Dietsch - first_name: J full_name: Seitz, J last_name: Seitz - first_name: EM full_name: Skoda, EM last_name: Skoda - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: A full_name: Schweda, A last_name: Schweda - first_name: M full_name: Teufel, M last_name: Teufel citation: ama: Knoll-Pientka N, Schils D, Pasternak K, et al. Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women. J Eat Disord. 2025;13(1):87. apa: Knoll-Pientka, N., Schils, D., Pasternak, K., Czarnetzky, S., Jansen, C., Gradl-Dietsch, G., Seitz, J., Skoda, E., Libuda, L., Schweda, A., & Teufel, M. (2025). Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women. J Eat Disord, 13(1), 87. bibtex: '@article{Knoll-Pientka_Schils_Pasternak_Czarnetzky_Jansen_Gradl-Dietsch_Seitz_Skoda_Libuda_Schweda_et al._2025, title={Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women.}, volume={13}, number={1}, journal={J Eat Disord}, author={Knoll-Pientka, N and Schils, D and Pasternak, K and Czarnetzky, S and Jansen, C and Gradl-Dietsch, G and Seitz, J and Skoda, EM and Libuda, Lars and Schweda, A and et al.}, year={2025}, pages={87} }' chicago: 'Knoll-Pientka, N, D Schils, K Pasternak, S Czarnetzky, C Jansen, G Gradl-Dietsch, J Seitz, et al. “Can Bioelectrical Impedance Analysis Be Used to Identify Water Loading in Patients with Anorexia Nervosa?- Implications from Experimental Measurements in Young, Healthy, and Normal Weight Women.” J Eat Disord 13, no. 1 (2025): 87.' ieee: N. Knoll-Pientka et al., “Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women.,” J Eat Disord, vol. 13, no. 1, p. 87, 2025. mla: Knoll-Pientka, N., et al. “Can Bioelectrical Impedance Analysis Be Used to Identify Water Loading in Patients with Anorexia Nervosa?- Implications from Experimental Measurements in Young, Healthy, and Normal Weight Women.” J Eat Disord, vol. 13, no. 1, 2025, p. 87. short: N. Knoll-Pientka, D. Schils, K. Pasternak, S. Czarnetzky, C. Jansen, G. Gradl-Dietsch, J. Seitz, E. Skoda, L. Libuda, A. Schweda, M. Teufel, J Eat Disord 13 (2025) 87. date_created: 2025-06-30T10:24:32Z date_updated: 2025-06-30T10:26:06Z department: - _id: '35' - _id: '17' - _id: '22' external_id: pmid: - '40390023' intvolume: ' 13' issue: '1' language: - iso: eng page: '87' pmid: '1' publication: J Eat Disord publication_identifier: issn: - 2050-2974 status: public title: Can bioelectrical impedance analysis be used to identify water loading in patients with anorexia nervosa?- Implications from experimental measurements in young, healthy, and normal weight women. type: journal_article user_id: '88682' volume: 13 year: '2025' ... --- _id: '52712' author: - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: Buyken A, Libuda L. Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft. DGEwissen. Published online 2024. apa: Buyken, A., & Libuda, L. (2024). Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft. DGEwissen. bibtex: '@article{Buyken_Libuda_2024, title={Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft}, journal={DGEwissen}, author={Buyken, Anette and Libuda, Lars}, year={2024} }' chicago: Buyken, Anette, and Lars Libuda. “Ernährung Und Alltagsbewältigung - Ein Spannungsfeld Für Individuum, Haushalt Und Gesellschaft.” DGEwissen, 2024. ieee: A. Buyken and L. Libuda, “Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft,” DGEwissen, 2024. mla: Buyken, Anette, and Lars Libuda. “Ernährung Und Alltagsbewältigung - Ein Spannungsfeld Für Individuum, Haushalt Und Gesellschaft.” DGEwissen, 2024. short: A. Buyken, L. Libuda, DGEwissen (2024). date_created: 2024-03-21T14:56:44Z date_updated: 2024-03-21T14:57:27Z department: - _id: '35' - _id: '17' - _id: '22' language: - iso: eng popular_science: '1' publication: DGEwissen status: public title: Ernährung und Alltagsbewältigung - Ein Spannungsfeld für Individuum, Haushalt und Gesellschaft type: journal_article user_id: '88682' year: '2024' ... --- _id: '52713' abstract: - lang: eng text: "ABSTRACT\r\n\t \r\n\t \ OBJECTIVE:\r\n\t The aim of this analysis was to investigate whether habitual intake of total dairy (TD) or different dairy types (liquid, solid, fermented, not-fermented, low-fat, high-fat, low-sugar and high-sugar dairy) during adolescence is associated with biomarkers of low-grade inflammation as well as risk factors of type 2 diabetes in young adulthood.\r\n\t \ \r\n\t \r\n\t DESIGN:\r\n\t \ Multivariable linear regression analyses were used to investigate prospective associations between estimated TD intake as well as intake of different types of dairy and a pro-inflammatory score, based on hsCRP, IL-6, IL-18, leptin and adiponectin, and insulin resistance assessed as HOMA2-IR in an open cohort study.\r\n\t \r\n\t \r\n\t \ SETTING:\r\n\t Dortmund, Germany\r\n\t \ \r\n\t \r\n\t PARTICIPANTS:\r\n\t \ Data from participants (n=375) of the DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study were included, for whom at least two 3-day weighed dietary records during adolescence (median age: 11 years) and one blood sample in young adulthood (>18 years) were available.\r\n\t \r\n\t \ \r\n\t RESULTS:\r\n\t \ There was no statistically significant association between TD intake or intake of any dairy type and the pro-inflammatory score (all p>0.05). TD intake as well as each dairy type intake and insulin resistance also showed no association (all p>0.05).\r\n\t \r\n\t \r\n\t \ CONCLUSIONS:\r\n\t The habitual intake of dairy or individual types of dairy during adolescence does not seem to have a major impact on low-grade systemic inflammation and insulin resistance in the long term. There was no indication regarding a restriction of dairy intake for healthy children and adolescents in terms of diabetes risk reduction.\r\n\t \ " author: - first_name: E full_name: Hohoff, E last_name: Hohoff - first_name: N full_name: Jankovic, N last_name: Jankovic - first_name: I full_name: Perrar, I last_name: Perrar - first_name: ME full_name: Schnermann, ME last_name: Schnermann - first_name: C full_name: Herder, C last_name: Herder - first_name: U full_name: Nöthlings, U last_name: Nöthlings - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: U full_name: Alexy, U last_name: Alexy citation: ama: Hohoff E, Jankovic N, Perrar I, et al. The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study. Public Health Nutrition. Published online 2024:1-26. doi:10.1017/s1368980024000624 apa: Hohoff, E., Jankovic, N., Perrar, I., Schnermann, M., Herder, C., Nöthlings, U., Libuda, L., & Alexy, U. (2024). The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study. Public Health Nutrition, 1–26. https://doi.org/10.1017/s1368980024000624 bibtex: '@article{Hohoff_Jankovic_Perrar_Schnermann_Herder_Nöthlings_Libuda_Alexy_2024, title={The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study}, DOI={10.1017/s1368980024000624}, journal={Public Health Nutrition}, publisher={Cambridge University Press (CUP)}, author={Hohoff, E and Jankovic, N and Perrar, I and Schnermann, ME and Herder, C and Nöthlings, U and Libuda, Lars and Alexy, U}, year={2024}, pages={1–26} }' chicago: Hohoff, E, N Jankovic, I Perrar, ME Schnermann, C Herder, U Nöthlings, Lars Libuda, and U Alexy. “The Association between Dairy Intake in Adolescents with Inflammation and Risk Markers of Type 2 Diabetes during Young Adulthood – Results of the DONALD Study.” Public Health Nutrition, 2024, 1–26. https://doi.org/10.1017/s1368980024000624. ieee: 'E. Hohoff et al., “The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study,” Public Health Nutrition, pp. 1–26, 2024, doi: 10.1017/s1368980024000624.' mla: Hohoff, E., et al. “The Association between Dairy Intake in Adolescents with Inflammation and Risk Markers of Type 2 Diabetes during Young Adulthood – Results of the DONALD Study.” Public Health Nutrition, Cambridge University Press (CUP), 2024, pp. 1–26, doi:10.1017/s1368980024000624. short: E. Hohoff, N. Jankovic, I. Perrar, M. Schnermann, C. Herder, U. Nöthlings, L. Libuda, U. Alexy, Public Health Nutrition (2024) 1–26. date_created: 2024-03-21T14:58:10Z date_updated: 2024-04-25T09:49:44Z department: - _id: '35' - _id: '17' - _id: '22' doi: 10.1017/s1368980024000624 keyword: - Public Health - Environmental and Occupational Health - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng page: 1-26 publication: Public Health Nutrition publication_identifier: issn: - 1368-9800 - 1475-2727 publication_status: published publisher: Cambridge University Press (CUP) status: public title: The association between dairy intake in adolescents with inflammation and risk markers of type 2 diabetes during young adulthood – results of the DONALD study type: journal_article user_id: '88682' year: '2024' ... --- _id: '50352' author: - first_name: AE full_name: Kolbaum, AE last_name: Kolbaum - first_name: C full_name: Jung, C last_name: Jung - first_name: A full_name: Jaeger, A last_name: Jaeger - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: O full_name: Lindtner, O last_name: Lindtner citation: ama: 'Kolbaum A, Jung C, Jaeger A, Libuda L, Lindtner O. Assessment of long-term dietary cadmium exposure in children in Germany: Does consideration of data from total diet studies reduce uncertainties from food monitoring programmes? Food Chem Toxicol. 2023;184:114404.' apa: 'Kolbaum, A., Jung, C., Jaeger, A., Libuda, L., & Lindtner, O. (2023). Assessment of long-term dietary cadmium exposure in children in Germany: Does consideration of data from total diet studies reduce uncertainties from food monitoring programmes? Food Chem Toxicol, 184, 114404.' bibtex: '@article{Kolbaum_Jung_Jaeger_Libuda_Lindtner_2023, title={Assessment of long-term dietary cadmium exposure in children in Germany: Does consideration of data from total diet studies reduce uncertainties from food monitoring programmes?}, volume={184}, journal={Food Chem Toxicol}, author={Kolbaum, AE and Jung, C and Jaeger, A and Libuda, Lars and Lindtner, O}, year={2023}, pages={114404} }' chicago: 'Kolbaum, AE, C Jung, A Jaeger, Lars Libuda, and O Lindtner. “Assessment of Long-Term Dietary Cadmium Exposure in Children in Germany: Does Consideration of Data from Total Diet Studies Reduce Uncertainties from Food Monitoring Programmes?” Food Chem Toxicol 184 (2023): 114404.' ieee: 'A. Kolbaum, C. Jung, A. Jaeger, L. Libuda, and O. Lindtner, “Assessment of long-term dietary cadmium exposure in children in Germany: Does consideration of data from total diet studies reduce uncertainties from food monitoring programmes?,” Food Chem Toxicol, vol. 184, p. 114404, 2023.' mla: 'Kolbaum, AE, et al. “Assessment of Long-Term Dietary Cadmium Exposure in Children in Germany: Does Consideration of Data from Total Diet Studies Reduce Uncertainties from Food Monitoring Programmes?” Food Chem Toxicol, vol. 184, 2023, p. 114404.' short: A. Kolbaum, C. Jung, A. Jaeger, L. Libuda, O. Lindtner, Food Chem Toxicol 184 (2023) 114404. date_created: 2024-01-09T08:45:27Z date_updated: 2024-01-09T08:46:35Z department: - _id: '35' - _id: '17' - _id: '22' external_id: pmid: - '38142766' intvolume: ' 184' language: - iso: eng page: '114404' pmid: '1' publication: Food Chem Toxicol publication_identifier: issn: - 0278-6915 - 1873-6351 status: public title: 'Assessment of long-term dietary cadmium exposure in children in Germany: Does consideration of data from total diet studies reduce uncertainties from food monitoring programmes?' type: journal_article user_id: '88682' volume: 184 year: '2023' ... --- _id: '36505' abstract: - lang: eng text: Young adults with a later chronotype are vulnerable for a discrepancy in sleep rhythm between work- and free days, called social jet lag (SJL). This study analysed (i) chronotype/SJL association with visceral fat/skeletal muscle mass, (ii) the attribution to physical activity behaviour, and (iii) chronotype-specific changes in physical activity behaviour in young adults during the Covid-19 pandemic lockdown. Chronotype and SJL were derived from the Munich-Chrono-Type-Questionnaire in 320 German students (age 18–25 years) from September 2019 to January 2020, 156 of these participated in an online follow-up survey in June 2020. Body composition was assessed by bioimpedance analysis at baseline. Multivariable linear regression analyses were used to relate chronotype/SJL to body composition; the contribution of self-reported physical activity was tested by mediation analysis. At baseline, a later chronotype and a larger SJL were associated with a higher visceral fat mass (P<0.05), this relation was notably mediated by the attention to physical activity (P<0.05). Chronotype (P = 0.02) but not SJL (P = 0.87) was inversely associated with skeletal muscle mass. During the pandemic lockdown, chronotype hardly changed, but SJL was reduced. Timing and physical activity behaviour remained in most participants and changes were unrelated to chronotype (all P>0.07). A later chronotype/higher SJL may increase the risk of a higher visceral fat mass even in this relatively healthy sample, which may be partly due to their physical activity behaviour. Despite a reduction in SJL during the pandemic lockdown, later chronotypes did not change their physical activity behaviour more than earlier chronotypes. article_number: e0279620 author: - first_name: Betina full_name: Krueger, Betina id: '49428' last_name: Krueger orcid: 0000-0001-5351-1785 - first_name: Bianca full_name: Stutz, Bianca id: '77099' last_name: Stutz - first_name: Nicole full_name: Jankovic, Nicole last_name: Jankovic - first_name: Ute full_name: Alexy, Ute last_name: Alexy - first_name: Anna full_name: Kilanowski, Anna last_name: Kilanowski - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anette E. full_name: Buyken, Anette E. id: '65985' last_name: Buyken citation: ama: 'Krueger B, Stutz B, Jankovic N, et al. The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown. PLOS ONE. 2023;18(1). doi:10.1371/journal.pone.0279620' apa: 'Krueger, B., Stutz, B., Jankovic, N., Alexy, U., Kilanowski, A., Libuda, L., & Buyken, A. E. (2023). The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown. PLOS ONE, 18(1), Article e0279620. https://doi.org/10.1371/journal.pone.0279620' bibtex: '@article{Krueger_Stutz_Jankovic_Alexy_Kilanowski_Libuda_Buyken_2023, title={The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown}, volume={18}, DOI={10.1371/journal.pone.0279620}, number={1e0279620}, journal={PLOS ONE}, publisher={Public Library of Science (PLoS)}, author={Krueger, Betina and Stutz, Bianca and Jankovic, Nicole and Alexy, Ute and Kilanowski, Anna and Libuda, Lars and Buyken, Anette E.}, year={2023} }' chicago: 'Krueger, Betina, Bianca Stutz, Nicole Jankovic, Ute Alexy, Anna Kilanowski, Lars Libuda, and Anette E. Buyken. “The Association of Chronotype and Social Jet Lag with Body Composition in German Students: The Role of Physical Activity Behaviour and the Impact of the Pandemic Lockdown.” PLOS ONE 18, no. 1 (2023). https://doi.org/10.1371/journal.pone.0279620.' ieee: 'B. Krueger et al., “The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown,” PLOS ONE, vol. 18, no. 1, Art. no. e0279620, 2023, doi: 10.1371/journal.pone.0279620.' mla: 'Krueger, Betina, et al. “The Association of Chronotype and Social Jet Lag with Body Composition in German Students: The Role of Physical Activity Behaviour and the Impact of the Pandemic Lockdown.” PLOS ONE, vol. 18, no. 1, e0279620, Public Library of Science (PLoS), 2023, doi:10.1371/journal.pone.0279620.' short: B. Krueger, B. Stutz, N. Jankovic, U. Alexy, A. Kilanowski, L. Libuda, A.E. Buyken, PLOS ONE 18 (2023). date_created: 2023-01-13T07:15:13Z date_updated: 2023-01-24T11:54:46Z department: - _id: '35' - _id: '22' doi: 10.1371/journal.pone.0279620 intvolume: ' 18' issue: '1' keyword: - Multidisciplinary language: - iso: eng publication: PLOS ONE publication_identifier: issn: - 1932-6203 publication_status: published publisher: Public Library of Science (PLoS) status: public title: 'The association of chronotype and social jet lag with body composition in German students: The role of physical activity behaviour and the impact of the pandemic lockdown' type: journal_article user_id: '61597' volume: 18 year: '2023' ... --- _id: '41456' abstract: - lang: eng text: "Abstract\r\n Background\r\n \ The German total diet study (TDS)—BfR MEAL Study—established its food list in 2016 based on food consumption data of children (0.5–<5 years) and adults (14–80 years). The list consists of 356 foods selected for analysis in order to ensure ≥90% coverage of the diet. Recently, new food consumption data for children (0.5–<6 and 6–<12 years) in Germany became available, which raised the opportunity to evaluate the applicability of the MEAL food list 2016 on new data.\r\n \r\n Objective\r\n \ We tested the hypotheses that the MEAL food list 2016 also covers ≥90% of the diet of the new collected food consumption data, and that the selection of foods from younger children and adults was sufficient to also cover the middle age group (6–<12 years). Strategies for updating the existing food list were assessed.\r\n \r\n Methods\r\n \ Three approaches evaluated the reusability and potential adjustment strategies of the existing food list. Approach 1 applied the existing food list to new food consumption data. Approach 2 allowed the extension of the existing food list to improve coverage of food consumption. Approach 3 set up a new food list based on the new data.\r\n \r\n \ Results\r\n The MEAL food list 2016 covered 94% of the overall diet of the new collected food consumption data. The diet of the middle age group was sufficiently covered with 91%. However, coverage on main food group or population subgroup level was <90% in some cases. Approach 3 most accurately identified relevant modifications to the existing food list. 94% of the MEAL food list 2016 could be re-used and 51 new foods were identified as potentially relevant.\r\n \r\n Significance\r\n \ The results suggest that a high investment in the coverage of a TDS food list will lower the effort and the resources to keep data updated in the long-term.\r\n \r\n Impact\r\n \ There is no established approach to update a TDS food list. This study provides comparative approaches to handle newly collected food consumption data for follow-on TDS activities. The results provide useful information for institutions planning or updating a TDS. Furthermore, new food consumption data for children in Germany recently became available and are here presented for the first time.\r\n " author: - first_name: Anna Elena full_name: Kolbaum, Anna Elena last_name: Kolbaum - first_name: Sebastian full_name: Ptok, Sebastian last_name: Ptok - first_name: Christian full_name: Jung, Christian last_name: Jung - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Oliver full_name: Lindtner, Oliver last_name: Lindtner citation: ama: Kolbaum AE, Ptok S, Jung C, Libuda L, Lindtner O. Reusability of Germany´s total diet study food list upon availability of new food consumption data—comparison of three update strategies. Journal of Exposure Science &amp; Environmental Epidemiology. Published online 2023. doi:10.1038/s41370-023-00522-4 apa: Kolbaum, A. E., Ptok, S., Jung, C., Libuda, L., & Lindtner, O. (2023). Reusability of Germany´s total diet study food list upon availability of new food consumption data—comparison of three update strategies. Journal of Exposure Science &amp; Environmental Epidemiology. https://doi.org/10.1038/s41370-023-00522-4 bibtex: '@article{Kolbaum_Ptok_Jung_Libuda_Lindtner_2023, title={Reusability of Germany´s total diet study food list upon availability of new food consumption data—comparison of three update strategies}, DOI={10.1038/s41370-023-00522-4}, journal={Journal of Exposure Science &amp; Environmental Epidemiology}, publisher={Springer Science and Business Media LLC}, author={Kolbaum, Anna Elena and Ptok, Sebastian and Jung, Christian and Libuda, Lars and Lindtner, Oliver}, year={2023} }' chicago: Kolbaum, Anna Elena, Sebastian Ptok, Christian Jung, Lars Libuda, and Oliver Lindtner. “Reusability of Germany´s Total Diet Study Food List upon Availability of New Food Consumption Data—Comparison of Three Update Strategies.” Journal of Exposure Science &amp; Environmental Epidemiology, 2023. https://doi.org/10.1038/s41370-023-00522-4. ieee: 'A. E. Kolbaum, S. Ptok, C. Jung, L. Libuda, and O. Lindtner, “Reusability of Germany´s total diet study food list upon availability of new food consumption data—comparison of three update strategies,” Journal of Exposure Science &amp; Environmental Epidemiology, 2023, doi: 10.1038/s41370-023-00522-4.' mla: Kolbaum, Anna Elena, et al. “Reusability of Germany´s Total Diet Study Food List upon Availability of New Food Consumption Data—Comparison of Three Update Strategies.” Journal of Exposure Science &amp; Environmental Epidemiology, Springer Science and Business Media LLC, 2023, doi:10.1038/s41370-023-00522-4. short: A.E. Kolbaum, S. Ptok, C. Jung, L. Libuda, O. Lindtner, Journal of Exposure Science &amp; Environmental Epidemiology (2023). date_created: 2023-02-02T08:33:12Z date_updated: 2023-02-02T08:33:33Z department: - _id: '35' - _id: '17' - _id: '22' doi: 10.1038/s41370-023-00522-4 keyword: - Public Health - Environmental and Occupational Health - Pollution - Toxicology - Epidemiology language: - iso: eng publication: Journal of Exposure Science & Environmental Epidemiology publication_identifier: issn: - 1559-0631 - 1559-064X publication_status: published publisher: Springer Science and Business Media LLC status: public title: Reusability of Germany´s total diet study food list upon availability of new food consumption data—comparison of three update strategies type: journal_article user_id: '88682' year: '2023' ... --- _id: '45813' abstract: - lang: eng text: A previous follow-up of the GINIplus study showed that breastfeeding could protect against early eczema. However, effects diminished in adolescence, possibly indicating a “rebound effect” in breastfed children after initial protection. We evaluated the role of early eczema until three years of age on allergies until young adulthood and assessed whether early eczema modifies the association between breastfeeding and allergies. Data from GINIplus until 20-years of age (N = 4058) were considered. Information on atopic eczema, asthma, and rhinitis was based on reported physician’s diagnoses. Adjusted Odds Ratios (aOR) were modelled by using generalized estimating equations. Early eczema was associated with eczema (aORs = 3.2–14.4), asthma (aORs = 2.2–2.7), and rhinitis (aORs = 1.2–2.7) until young adulthood. For eczema, this association decreased with age (p-for-interaction = 0.002–0.006). Longitudinal models did not show associations between breastfeeding and the respective allergies from 5 to 20 years of age. Moreover, early eczema generally did not modify the association between milk feeding and allergies except for rhinitis in participants without family history of atopy. Early eczema strongly predicts allergies until young adulthood. While preventive effects of full breastfeeding on eczema in infants with family history of atopy does not persist until young adulthood, the hypothesis of a rebound effect after initial protection cannot be confirmed. article_number: '2780' author: - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Birgit full_name: Filipiak-Pittroff, Birgit last_name: Filipiak-Pittroff - first_name: Marie full_name: Standl, Marie last_name: Standl - first_name: Tamara full_name: Schikowski, Tamara last_name: Schikowski - first_name: Andrea full_name: von Berg, Andrea last_name: von Berg - first_name: Sibylle full_name: Koletzko, Sibylle last_name: Koletzko - first_name: Carl-Peter full_name: Bauer, Carl-Peter last_name: Bauer - first_name: Joachim full_name: Heinrich, Joachim last_name: Heinrich - first_name: Dietrich full_name: Berdel, Dietrich last_name: Berdel - first_name: Monika full_name: Gappa, Monika last_name: Gappa citation: ama: Libuda L, Filipiak-Pittroff B, Standl M, et al. Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects? Nutrients. 2023;15(12). doi:10.3390/nu15122780 apa: Libuda, L., Filipiak-Pittroff, B., Standl, M., Schikowski, T., von Berg, A., Koletzko, S., Bauer, C.-P., Heinrich, J., Berdel, D., & Gappa, M. (2023). Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects? Nutrients, 15(12), Article 2780. https://doi.org/10.3390/nu15122780 bibtex: '@article{Libuda_Filipiak-Pittroff_Standl_Schikowski_von Berg_Koletzko_Bauer_Heinrich_Berdel_Gappa_2023, title={Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects?}, volume={15}, DOI={10.3390/nu15122780}, number={122780}, journal={Nutrients}, publisher={MDPI AG}, author={Libuda, Lars and Filipiak-Pittroff, Birgit and Standl, Marie and Schikowski, Tamara and von Berg, Andrea and Koletzko, Sibylle and Bauer, Carl-Peter and Heinrich, Joachim and Berdel, Dietrich and Gappa, Monika}, year={2023} }' chicago: Libuda, Lars, Birgit Filipiak-Pittroff, Marie Standl, Tamara Schikowski, Andrea von Berg, Sibylle Koletzko, Carl-Peter Bauer, Joachim Heinrich, Dietrich Berdel, and Monika Gappa. “Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects?” Nutrients 15, no. 12 (2023). https://doi.org/10.3390/nu15122780. ieee: 'L. Libuda et al., “Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects?,” Nutrients, vol. 15, no. 12, Art. no. 2780, 2023, doi: 10.3390/nu15122780.' mla: Libuda, Lars, et al. “Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects?” Nutrients, vol. 15, no. 12, 2780, MDPI AG, 2023, doi:10.3390/nu15122780. short: L. Libuda, B. Filipiak-Pittroff, M. Standl, T. Schikowski, A. von Berg, S. Koletzko, C.-P. Bauer, J. Heinrich, D. Berdel, M. Gappa, Nutrients 15 (2023). date_created: 2023-06-29T07:53:51Z date_updated: 2023-06-29T07:54:27Z department: - _id: '35' - _id: '17' - _id: '22' doi: 10.3390/nu15122780 intvolume: ' 15' issue: '12' keyword: - Food Science - Nutrition and Dietetics language: - iso: eng publication: Nutrients publication_identifier: issn: - 2072-6643 publication_status: published publisher: MDPI AG status: public title: Full Breastfeeding and Allergic Diseases—Long-Term Protection or Rebound Effects? type: journal_article user_id: '88682' volume: 15 year: '2023' ... --- _id: '33383' author: - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Stefanie full_name: Frölich, Stefanie last_name: Frölich - first_name: Christine full_name: Ludwig, Christine last_name: Ludwig - first_name: Nadja full_name: Knoll-Pientka, Nadja last_name: Knoll-Pientka - first_name: Börge full_name: Schmidt, Börge last_name: Schmidt - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: 'Bühlmeier J, Frölich S, Ludwig C, et al. Correction to: Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey. European Journal of Nutrition. 2022;61(6):3307-3308. doi:10.1007/s00394-022-02952-6' apa: 'Bühlmeier, J., Frölich, S., Ludwig, C., Knoll-Pientka, N., Schmidt, B., Föcker, M., & Libuda, L. (2022). Correction to: Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey. European Journal of Nutrition, 61(6), 3307–3308. https://doi.org/10.1007/s00394-022-02952-6' bibtex: '@article{Bühlmeier_Frölich_Ludwig_Knoll-Pientka_Schmidt_Föcker_Libuda_2022, title={Correction to: Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey}, volume={61}, DOI={10.1007/s00394-022-02952-6}, number={6}, journal={European Journal of Nutrition}, publisher={Springer Science and Business Media LLC}, author={Bühlmeier, Judith and Frölich, Stefanie and Ludwig, Christine and Knoll-Pientka, Nadja and Schmidt, Börge and Föcker, Manuel and Libuda, Lars}, year={2022}, pages={3307–3308} }' chicago: 'Bühlmeier, Judith, Stefanie Frölich, Christine Ludwig, Nadja Knoll-Pientka, Börge Schmidt, Manuel Föcker, and Lars Libuda. “Correction to: Changes in Patterns of Eating Habits and Food Intake during the First German COVID-19 Lockdown: Results of a Cross-Sectional Online Survey.” European Journal of Nutrition 61, no. 6 (2022): 3307–8. https://doi.org/10.1007/s00394-022-02952-6.' ieee: 'J. Bühlmeier et al., “Correction to: Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey,” European Journal of Nutrition, vol. 61, no. 6, pp. 3307–3308, 2022, doi: 10.1007/s00394-022-02952-6.' mla: 'Bühlmeier, Judith, et al. “Correction to: Changes in Patterns of Eating Habits and Food Intake during the First German COVID-19 Lockdown: Results of a Cross-Sectional Online Survey.” European Journal of Nutrition, vol. 61, no. 6, Springer Science and Business Media LLC, 2022, pp. 3307–08, doi:10.1007/s00394-022-02952-6.' short: J. Bühlmeier, S. Frölich, C. Ludwig, N. Knoll-Pientka, B. Schmidt, M. Föcker, L. Libuda, European Journal of Nutrition 61 (2022) 3307–3308. date_created: 2022-09-15T09:17:02Z date_updated: 2022-09-15T09:46:35Z department: - _id: '17' doi: 10.1007/s00394-022-02952-6 intvolume: ' 61' issue: '6' keyword: - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng page: 3307-3308 publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Correction to: Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey' type: journal_article user_id: '89838' volume: 61 year: '2022' ... --- _id: '33382' author: - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Paul-Martin full_name: Holterhus, Paul-Martin last_name: Holterhus - first_name: Alexandra full_name: Kulle, Alexandra last_name: Kulle - first_name: Cordula full_name: Kiewert, Cordula last_name: Kiewert - first_name: Ronny full_name: Kuhnert, Ronny last_name: Kuhnert - first_name: Caroline full_name: Cohrdes, Caroline last_name: Cohrdes - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann citation: ama: 'Hirtz R, Libuda L, Hinney A, et al. Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population. Journal of Affective Disorders. 2022;318:103-112. doi:10.1016/j.jad.2022.08.092' apa: 'Hirtz, R., Libuda, L., Hinney, A., Föcker, M., Bühlmeier, J., Holterhus, P.-M., Kulle, A., Kiewert, C., Kuhnert, R., Cohrdes, C., Peters, T., Hebebrand, J., & Grasemann, C. (2022). Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population. Journal of Affective Disorders, 318, 103–112. https://doi.org/10.1016/j.jad.2022.08.092' bibtex: '@article{Hirtz_Libuda_Hinney_Föcker_Bühlmeier_Holterhus_Kulle_Kiewert_Kuhnert_Cohrdes_et al._2022, title={Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population}, volume={318}, DOI={10.1016/j.jad.2022.08.092}, journal={Journal of Affective Disorders}, publisher={Elsevier BV}, author={Hirtz, Raphael and Libuda, Lars and Hinney, Anke and Föcker, Manuel and Bühlmeier, Judith and Holterhus, Paul-Martin and Kulle, Alexandra and Kiewert, Cordula and Kuhnert, Ronny and Cohrdes, Caroline and et al.}, year={2022}, pages={103–112} }' chicago: 'Hirtz, Raphael, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, et al. “Age at Menarche Relates to Depression in Adolescent Girls: Comparing a Clinical Sample to the General Pediatric Population.” Journal of Affective Disorders 318 (2022): 103–12. https://doi.org/10.1016/j.jad.2022.08.092.' ieee: 'R. Hirtz et al., “Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population,” Journal of Affective Disorders, vol. 318, pp. 103–112, 2022, doi: 10.1016/j.jad.2022.08.092.' mla: 'Hirtz, Raphael, et al. “Age at Menarche Relates to Depression in Adolescent Girls: Comparing a Clinical Sample to the General Pediatric Population.” Journal of Affective Disorders, vol. 318, Elsevier BV, 2022, pp. 103–12, doi:10.1016/j.jad.2022.08.092.' short: R. Hirtz, L. Libuda, A. Hinney, M. Föcker, J. Bühlmeier, P.-M. Holterhus, A. Kulle, C. Kiewert, R. Kuhnert, C. Cohrdes, T. Peters, J. Hebebrand, C. Grasemann, Journal of Affective Disorders 318 (2022) 103–112. date_created: 2022-09-15T09:15:58Z date_updated: 2022-09-15T09:48:03Z department: - _id: '17' doi: 10.1016/j.jad.2022.08.092 extern: '1' intvolume: ' 318' keyword: - Psychiatry and Mental health - Clinical Psychology language: - iso: eng page: 103-112 publication: Journal of Affective Disorders publication_identifier: issn: - 0165-0327 publication_status: published publisher: Elsevier BV status: public title: 'Age at menarche relates to depression in adolescent girls: Comparing a clinical sample to the general pediatric population' type: journal_article user_id: '89838' volume: 318 year: '2022' ... --- _id: '32326' abstract: - lang: eng text: AbstractGenetic factors are relevant for both eating disorders and body weight regulation. A recent genome-wide association study (GWAS) for anorexia nervosa (AN) detected eight genome-wide significant chromosomal loci. One of these loci, rs10747478, was also genome-wide and significantly associated with body mass index (BMI). The nearest coding gene is the Polypyrimidine Tract Binding Protein 2 gene (PTBP2). To detect mutations in PTBP2, Sanger sequencing of the coding region was performed in 192 female patients with AN (acute or recovered) and 191 children or adolescents with (extreme) obesity. Twenty-five variants were identified. Twenty-three of these were predicted to be pathogenic or functionally relevant in at least one in silico tool. Two novel synonymous variants (p.Ala77Ala and p.Asp195Asp), one intronic SNP (rs188987764), and the intronic deletion (rs561340981) located in the highly conserved region of PTBP2 may have functional consequences. Ten of 20 genes interacting with PTBP2 were studied for their impact on body weight regulation based on either previous functional studies or GWAS hits for body weight or BMI. In a GWAS for BMI (Pulit et al. 2018), the number of genome-wide significant associations at the PTBP2 locus was different between males (60 variants) and females (two variants, one of these also significant in males). More than 65% of these 61 variants showed differences in the effect size pertaining to BMI between sexes (absolute value of Z-score >2, two-sided p < 0.05). One LD block overlapping 5′UTR and all coding regions of PTBP2 comprises 56 significant variants in males. The analysis based on sex-stratified BMI GWAS summary statistics implies that PTBP2 may have a more pronounced effect on body weight regulation in males than in females. article_number: '241' author: - first_name: Yiran full_name: Zheng, Yiran last_name: Zheng - first_name: Luisa Sophie full_name: Rajcsanyi, Luisa Sophie last_name: Rajcsanyi - first_name: Beate full_name: Herpertz-Dahlmann, Beate last_name: Herpertz-Dahlmann - first_name: Jochen full_name: Seitz, Jochen last_name: Seitz - first_name: Martina full_name: de Zwaan, Martina last_name: de Zwaan - first_name: Wolfgang full_name: Herzog, Wolfgang last_name: Herzog - first_name: Stefan full_name: Ehrlich, Stefan last_name: Ehrlich - first_name: Stephan full_name: Zipfel, Stephan last_name: Zipfel - first_name: Katrin full_name: Giel, Katrin last_name: Giel - first_name: Karin full_name: Egberts, Karin last_name: Egberts - first_name: Roland full_name: Burghardt, Roland last_name: Burghardt - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Saad full_name: Al-Lahham, Saad last_name: Al-Lahham - first_name: Triinu full_name: Peters, Triinu last_name: Peters - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Jochen full_name: Antel, Jochen last_name: Antel - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Anke full_name: Hinney, Anke last_name: Hinney citation: ama: Zheng Y, Rajcsanyi LS, Herpertz-Dahlmann B, et al. PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation. Translational Psychiatry. 2022;12(1). doi:10.1038/s41398-022-02018-5 apa: Zheng, Y., Rajcsanyi, L. S., Herpertz-Dahlmann, B., Seitz, J., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Giel, K., Egberts, K., Burghardt, R., Föcker, M., Al-Lahham, S., Peters, T., Libuda, L., Antel, J., Hebebrand, J., & Hinney, A. (2022). PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation. Translational Psychiatry, 12(1), Article 241. https://doi.org/10.1038/s41398-022-02018-5 bibtex: '@article{Zheng_Rajcsanyi_Herpertz-Dahlmann_Seitz_de Zwaan_Herzog_Ehrlich_Zipfel_Giel_Egberts_et al._2022, title={PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation}, volume={12}, DOI={10.1038/s41398-022-02018-5}, number={1241}, journal={Translational Psychiatry}, publisher={Springer Science and Business Media LLC}, author={Zheng, Yiran and Rajcsanyi, Luisa Sophie and Herpertz-Dahlmann, Beate and Seitz, Jochen and de Zwaan, Martina and Herzog, Wolfgang and Ehrlich, Stefan and Zipfel, Stephan and Giel, Katrin and Egberts, Karin and et al.}, year={2022} }' chicago: Zheng, Yiran, Luisa Sophie Rajcsanyi, Beate Herpertz-Dahlmann, Jochen Seitz, Martina de Zwaan, Wolfgang Herzog, Stefan Ehrlich, et al. “PTBP2 – a Gene with Relevance for Both Anorexia Nervosa and Body Weight Regulation.” Translational Psychiatry 12, no. 1 (2022). https://doi.org/10.1038/s41398-022-02018-5. ieee: 'Y. Zheng et al., “PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation,” Translational Psychiatry, vol. 12, no. 1, Art. no. 241, 2022, doi: 10.1038/s41398-022-02018-5.' mla: Zheng, Yiran, et al. “PTBP2 – a Gene with Relevance for Both Anorexia Nervosa and Body Weight Regulation.” Translational Psychiatry, vol. 12, no. 1, 241, Springer Science and Business Media LLC, 2022, doi:10.1038/s41398-022-02018-5. short: Y. Zheng, L.S. Rajcsanyi, B. Herpertz-Dahlmann, J. Seitz, M. de Zwaan, W. Herzog, S. Ehrlich, S. Zipfel, K. Giel, K. Egberts, R. Burghardt, M. Föcker, S. Al-Lahham, T. Peters, L. Libuda, J. Antel, J. Hebebrand, A. Hinney, Translational Psychiatry 12 (2022). date_created: 2022-07-06T15:14:13Z date_updated: 2022-10-26T15:49:24Z department: - _id: '35' doi: 10.1038/s41398-022-02018-5 intvolume: ' 12' issue: '1' keyword: - Biological Psychiatry - Cellular and Molecular Neuroscience - Psychiatry and Mental health language: - iso: eng publication: Translational Psychiatry publication_identifier: issn: - 2158-3188 publication_status: published publisher: Springer Science and Business Media LLC status: public title: PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation type: journal_article user_id: '88682' volume: 12 year: '2022' ... --- _id: '32328' abstract: - lang: eng text: "Abstract\r\n Purpose\r\n \ The COVID-19 pandemic and public measures have a direct impact on the nutrition situation; studies show changes in food consumption, eating behavior or body weight but complex pattern analyses of changes rarely exist.\r\n \ \r\n Methods\r\n \ During the first German lockdown, a web-based survey was conducted among adults. It included 33 questions about changes in food intake, eating habits and physical activity, as well as anthropometrics and sociodemographic factors. Patterns of change were calculated based on changes in food intake and eating habits using two-step cluster analysis. To identify influencing factors for assignment to the patterns of change, binary logistic regression analyses were performed.\r\n \r\n Results\r\n \ Data from 2103 participants (81% female, 40 ± 14 years) were considered for analysis. Increased stockpiling, cooking, and variation in preparation was reported by 50–70%. The constant pattern (C-P, 36%) reported little change besides the above. The health-oriented pattern (HO-P; 37%) reported eating more healthy foods, avoiding unhealthy foods, and eating less and less frequently. The emotional-driven pattern (ED-P; 28%) exhibits higher influence of emotions on eating behavior, less avoidance of unhealthy foods, and increased consumption of sweets, pastries, and alcohol. The odds of changing eating behavior either to HO-P or ED-P were higher in women, people with migration background, younger participants, and increased with BMI categories.\r\n \r\n \ Conclusion\r\n Both, the ED-P and HO-P, exhibit distinctive reactions in eating habits and food intake when dealing with a distressing experience. In subgroups, these may lead to disturbances in eating behavior and increase the risk for eating disorders and obesity.\r\n \ " author: - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Stefanie full_name: Frölich, Stefanie last_name: Frölich - first_name: Christine full_name: Ludwig, Christine last_name: Ludwig - first_name: Nadja full_name: Knoll-Pientka, Nadja last_name: Knoll-Pientka - first_name: Börge full_name: Schmidt, Börge last_name: Schmidt - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 citation: ama: 'Bühlmeier J, Frölich S, Ludwig C, et al. Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey. European Journal of Nutrition. Published online 2022. doi:10.1007/s00394-022-02919-7' apa: 'Bühlmeier, J., Frölich, S., Ludwig, C., Knoll-Pientka, N., Schmidt, B., Föcker, M., & Libuda, L. (2022). Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey. European Journal of Nutrition. https://doi.org/10.1007/s00394-022-02919-7' bibtex: '@article{Bühlmeier_Frölich_Ludwig_Knoll-Pientka_Schmidt_Föcker_Libuda_2022, title={Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey}, DOI={10.1007/s00394-022-02919-7}, journal={European Journal of Nutrition}, publisher={Springer Science and Business Media LLC}, author={Bühlmeier, Judith and Frölich, Stefanie and Ludwig, Christine and Knoll-Pientka, Nadja and Schmidt, Börge and Föcker, Manuel and Libuda, Lars}, year={2022} }' chicago: 'Bühlmeier, Judith, Stefanie Frölich, Christine Ludwig, Nadja Knoll-Pientka, Börge Schmidt, Manuel Föcker, and Lars Libuda. “Changes in Patterns of Eating Habits and Food Intake during the First German COVID-19 Lockdown: Results of a Cross-Sectional Online Survey.” European Journal of Nutrition, 2022. https://doi.org/10.1007/s00394-022-02919-7.' ieee: 'J. Bühlmeier et al., “Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey,” European Journal of Nutrition, 2022, doi: 10.1007/s00394-022-02919-7.' mla: 'Bühlmeier, Judith, et al. “Changes in Patterns of Eating Habits and Food Intake during the First German COVID-19 Lockdown: Results of a Cross-Sectional Online Survey.” European Journal of Nutrition, Springer Science and Business Media LLC, 2022, doi:10.1007/s00394-022-02919-7.' short: J. Bühlmeier, S. Frölich, C. Ludwig, N. Knoll-Pientka, B. Schmidt, M. Föcker, L. Libuda, European Journal of Nutrition (2022). date_created: 2022-07-06T15:15:01Z date_updated: 2022-10-26T15:48:54Z department: - _id: '35' doi: 10.1007/s00394-022-02919-7 keyword: - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Changes in patterns of eating habits and food intake during the first German COVID-19 lockdown: results of a cross-sectional online survey' type: journal_article user_id: '88682' year: '2022' ... --- _id: '33235' abstract: - lang: eng text: "Abstract\r\n Purpose\r\n \ We aimed to investigate whether parental and siblings’ sugar-sweetened beverage (SSB) intake had prospective impact on children’s SSB consumption, and the potential sex difference in these associations.\r\n \r\n \ Methods\r\n This study included a total of 904 children and their parents enrolled from 2004 to 2011 China Health and Nutrition Survey (CHNS) cohort study. SSB consumption information was estimated using a short dietary questionnaire and total energy intake was assessed with three-day 24-h dietary assessments at recruitment and follow-up surveys. Multivariate logistic or linear regression analyses were used to assess the association for SSB consumption between parents, siblings and children after adjusting for age, body mass index (BMI) z-score, household income and parental educational level.\r\n \r\n \ Results\r\n In this study, a majority (87.6%) of children consumed SSB. Among them, the median consumption of SSB was 70.3 ml/day per capita and 205.4 ml/day per consumer. Parental SSB consumption was relevant to children’s SSB consumption, and this association was more pronounced in boys than in girls. Meanwhile, fathers seemed to have a stronger impact on whether children consume SSB than mothers which was reflected by lower P and higher OR. Additionally, children’s SSB intake was prospectively associated with their older siblings’ SSB consumption (Pfor trend < 0.03).\r\n \r\n \ Conclusions\r\n Parental and older siblings’ SSB consumption was relevant to children’s SSB intake. Particularly, boys were more susceptible to parental impact than girls, and fathers seemed to have a greater influence on children than mothers.\r\n " author: - first_name: Xue-Ting full_name: Liu, Xue-Ting last_name: Liu - first_name: Jing-Yuan full_name: Xiong, Jing-Yuan last_name: Xiong - first_name: Yu-Jie full_name: Xu, Yu-Jie last_name: Xu - first_name: Li full_name: Zhao, Li last_name: Zhao - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Guo full_name: Cheng, Guo last_name: Cheng citation: ama: Liu X-T, Xiong J-Y, Xu Y-J, Zhao L, Libuda L, Cheng G. Prospective association of family members’ sugar-sweetened beverages intake with children’s sugar-sweetened beverages consumption in China. European Journal of Nutrition. Published online 2022. doi:10.1007/s00394-022-02971-3 apa: Liu, X.-T., Xiong, J.-Y., Xu, Y.-J., Zhao, L., Libuda, L., & Cheng, G. (2022). Prospective association of family members’ sugar-sweetened beverages intake with children’s sugar-sweetened beverages consumption in China. European Journal of Nutrition. https://doi.org/10.1007/s00394-022-02971-3 bibtex: '@article{Liu_Xiong_Xu_Zhao_Libuda_Cheng_2022, title={Prospective association of family members’ sugar-sweetened beverages intake with children’s sugar-sweetened beverages consumption in China}, DOI={10.1007/s00394-022-02971-3}, journal={European Journal of Nutrition}, publisher={Springer Science and Business Media LLC}, author={Liu, Xue-Ting and Xiong, Jing-Yuan and Xu, Yu-Jie and Zhao, Li and Libuda, Lars and Cheng, Guo}, year={2022} }' chicago: Liu, Xue-Ting, Jing-Yuan Xiong, Yu-Jie Xu, Li Zhao, Lars Libuda, and Guo Cheng. “Prospective Association of Family Members’ Sugar-Sweetened Beverages Intake with Children’s Sugar-Sweetened Beverages Consumption in China.” European Journal of Nutrition, 2022. https://doi.org/10.1007/s00394-022-02971-3. ieee: 'X.-T. Liu, J.-Y. Xiong, Y.-J. Xu, L. Zhao, L. Libuda, and G. Cheng, “Prospective association of family members’ sugar-sweetened beverages intake with children’s sugar-sweetened beverages consumption in China,” European Journal of Nutrition, 2022, doi: 10.1007/s00394-022-02971-3.' mla: Liu, Xue-Ting, et al. “Prospective Association of Family Members’ Sugar-Sweetened Beverages Intake with Children’s Sugar-Sweetened Beverages Consumption in China.” European Journal of Nutrition, Springer Science and Business Media LLC, 2022, doi:10.1007/s00394-022-02971-3. short: X.-T. Liu, J.-Y. Xiong, Y.-J. Xu, L. Zhao, L. Libuda, G. Cheng, European Journal of Nutrition (2022). date_created: 2022-08-30T13:08:18Z date_updated: 2022-10-26T15:48:20Z department: - _id: '35' doi: 10.1007/s00394-022-02971-3 keyword: - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng publication: European Journal of Nutrition publication_identifier: issn: - 1436-6207 - 1436-6215 publication_status: published publisher: Springer Science and Business Media LLC status: public title: Prospective association of family members’ sugar-sweetened beverages intake with children’s sugar-sweetened beverages consumption in China type: journal_article user_id: '88682' year: '2022' ... --- _id: '33234' author: - first_name: Roger A.H. full_name: Adan, Roger A.H. last_name: Adan - first_name: Francesca full_name: Cirulli, Francesca last_name: Cirulli - first_name: Louise full_name: Dye, Louise last_name: Dye - first_name: Suzanne full_name: Higgs, Suzanne last_name: Higgs - first_name: Kristien full_name: Aarts, Kristien last_name: Aarts - first_name: Eline M. full_name: van der Beek, Eline M. last_name: van der Beek - first_name: Jan K. full_name: Buitelaar, Jan K. last_name: Buitelaar - first_name: Frédéric full_name: Destrebecq, Frédéric last_name: Destrebecq - first_name: Elke full_name: De Witte, Elke last_name: De Witte - first_name: Tobias full_name: Hartmann, Tobias last_name: Hartmann - first_name: Aniko full_name: Korosi, Aniko last_name: Korosi - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Suzanne L. full_name: Dickson, Suzanne L. last_name: Dickson citation: ama: 'Adan RAH, Cirulli F, Dye L, et al. Towards new nutritional policies for brain health: A research perspective on future actions. Brain, Behavior, and Immunity. 2022;105:201-203. doi:10.1016/j.bbi.2022.07.012' apa: 'Adan, R. A. H., Cirulli, F., Dye, L., Higgs, S., Aarts, K., van der Beek, E. M., Buitelaar, J. K., Destrebecq, F., De Witte, E., Hartmann, T., Korosi, A., Libuda, L., & Dickson, S. L. (2022). Towards new nutritional policies for brain health: A research perspective on future actions. Brain, Behavior, and Immunity, 105, 201–203. https://doi.org/10.1016/j.bbi.2022.07.012' bibtex: '@article{Adan_Cirulli_Dye_Higgs_Aarts_van der Beek_Buitelaar_Destrebecq_De Witte_Hartmann_et al._2022, title={Towards new nutritional policies for brain health: A research perspective on future actions}, volume={105}, DOI={10.1016/j.bbi.2022.07.012}, journal={Brain, Behavior, and Immunity}, publisher={Elsevier BV}, author={Adan, Roger A.H. and Cirulli, Francesca and Dye, Louise and Higgs, Suzanne and Aarts, Kristien and van der Beek, Eline M. and Buitelaar, Jan K. and Destrebecq, Frédéric and De Witte, Elke and Hartmann, Tobias and et al.}, year={2022}, pages={201–203} }' chicago: 'Adan, Roger A.H., Francesca Cirulli, Louise Dye, Suzanne Higgs, Kristien Aarts, Eline M. van der Beek, Jan K. Buitelaar, et al. “Towards New Nutritional Policies for Brain Health: A Research Perspective on Future Actions.” Brain, Behavior, and Immunity 105 (2022): 201–3. https://doi.org/10.1016/j.bbi.2022.07.012.' ieee: 'R. A. H. Adan et al., “Towards new nutritional policies for brain health: A research perspective on future actions,” Brain, Behavior, and Immunity, vol. 105, pp. 201–203, 2022, doi: 10.1016/j.bbi.2022.07.012.' mla: 'Adan, Roger A. H., et al. “Towards New Nutritional Policies for Brain Health: A Research Perspective on Future Actions.” Brain, Behavior, and Immunity, vol. 105, Elsevier BV, 2022, pp. 201–03, doi:10.1016/j.bbi.2022.07.012.' short: R.A.H. Adan, F. Cirulli, L. Dye, S. Higgs, K. Aarts, E.M. van der Beek, J.K. Buitelaar, F. Destrebecq, E. De Witte, T. Hartmann, A. Korosi, L. Libuda, S.L. Dickson, Brain, Behavior, and Immunity 105 (2022) 201–203. date_created: 2022-08-30T13:07:25Z date_updated: 2022-10-26T15:47:15Z department: - _id: '35' doi: 10.1016/j.bbi.2022.07.012 intvolume: ' 105' keyword: - Behavioral Neuroscience - Endocrine and Autonomic Systems - Immunology language: - iso: eng page: 201-203 publication: Brain, Behavior, and Immunity publication_identifier: issn: - 0889-1591 publication_status: published publisher: Elsevier BV status: public title: 'Towards new nutritional policies for brain health: A research perspective on future actions' type: journal_article user_id: '88682' volume: 105 year: '2022' ... --- _id: '33385' abstract: - lang: eng text: "Abstract\r\n Background\r\n \ In Sub-Saharan African countries, rapid urbanization and increasing socio-economic status are associated with a transition to decreased physical activity (PA). A more sedentary lifestyle is linked to increased body fat leading to increments in leptin levels. Since rodent and human studies in high-income countries have shown that starvation-induced hypoleptinemia triggers high PA, efforts are warranted to pursue the hypothesis that low leptin levels in lean children of low- and middle-income countries (LMIC) are also associated with high PA.\r\n \r\n Methods\r\n \ In this cross-sectional study, we assessed seven-day PA with triaxial accelerometry (ActiGraph GT3X) among 223 primary school children (9 to 12 years of age) in rural Tanzania. Moderate-to-vigorous PA (MVPA) and total accelerometer counts per day were outcome variables. Leptin was determined using enzyme linked immunosorbent assay tests from dried blood spots. Anthropometric assessments were conducted and food insecurity and socio-demographic data were gathered using semi-structured interviews.\r\n \r\n \ Results\r\n In this sample of school children in rural Tanzania, leptin concentrations (median: 0.91 ng/mL, P25: 0.55, P75: 1.69), body mass index z-scores (median: -1.35, P25: -1.93, P75: -0.82), and height-for-age-z-scores (median: -1.16, P25: -1.96, P75: -0.61) were low. In contrast, PA levels were high with a median MVPA time of 119 min/day. Linear regression confirmed that leptin levels were negatively associated with MVPA (beta: -18.1; 95%CI: -29.7; -6.5; p = 0.002) and total accelerometer counts (beta: -90,256; 95%CI: -154,146; -26,365; p = 0.006). Children residing in areas with better infrastructure had lower MVPA levels (p < 0.001) and tended to have higher leptin levels (p = 0.062) than children residing in areas only reachable via dirt roads.\r\n \r\n \ Conclusion\r\n Our cross-sectional field study is the first that supports the hypothesis of low leptin levels as a potential endocrine trigger of high PA in lean children of a LMIC. We observed early signs of a PA transition towards a less active lifestyle in a subgroup residing in areas with better infrastructure that concomitantly tended to have higher leptin concentrations. Considering that area-dependent PA differences were more pronounced among girls than boys, whereas differences in leptin levels were less pronounced, not only biological, but also external factors explain PA transition.\r\n " article_number: '933' author: - first_name: Christine full_name: Ludwig, Christine last_name: Ludwig - first_name: Nadja full_name: Knoll-Pientka, Nadja last_name: Knoll-Pientka - first_name: Akwilina full_name: Mwanri, Akwilina last_name: Mwanri - first_name: Celina full_name: Erfle, Celina last_name: Erfle - first_name: Vincent full_name: Onywera, Vincent last_name: Onywera - first_name: Mark S. full_name: Tremblay, Mark S. last_name: Tremblay - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Agnes full_name: Luzak, Agnes last_name: Luzak - first_name: Maike full_name: Ferland, Maike last_name: Ferland - first_name: Holger full_name: Schulz, Holger last_name: Schulz - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand citation: ama: Ludwig C, Knoll-Pientka N, Mwanri A, et al. Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania. BMC Public Health. 2022;22(1). doi:10.1186/s12889-022-12949-9 apa: Ludwig, C., Knoll-Pientka, N., Mwanri, A., Erfle, C., Onywera, V., Tremblay, M. S., Bühlmeier, J., Luzak, A., Ferland, M., Schulz, H., Libuda, L., & Hebebrand, J. (2022). Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania. BMC Public Health, 22(1), Article 933. https://doi.org/10.1186/s12889-022-12949-9 bibtex: '@article{Ludwig_Knoll-Pientka_Mwanri_Erfle_Onywera_Tremblay_Bühlmeier_Luzak_Ferland_Schulz_et al._2022, title={Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania}, volume={22}, DOI={10.1186/s12889-022-12949-9}, number={1933}, journal={BMC Public Health}, publisher={Springer Science and Business Media LLC}, author={Ludwig, Christine and Knoll-Pientka, Nadja and Mwanri, Akwilina and Erfle, Celina and Onywera, Vincent and Tremblay, Mark S. and Bühlmeier, Judith and Luzak, Agnes and Ferland, Maike and Schulz, Holger and et al.}, year={2022} }' chicago: Ludwig, Christine, Nadja Knoll-Pientka, Akwilina Mwanri, Celina Erfle, Vincent Onywera, Mark S. Tremblay, Judith Bühlmeier, et al. “Low Leptin Levels Are Associated with Elevated Physical Activity among Lean School Children in Rural Tanzania.” BMC Public Health 22, no. 1 (2022). https://doi.org/10.1186/s12889-022-12949-9. ieee: 'C. Ludwig et al., “Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania,” BMC Public Health, vol. 22, no. 1, Art. no. 933, 2022, doi: 10.1186/s12889-022-12949-9.' mla: Ludwig, Christine, et al. “Low Leptin Levels Are Associated with Elevated Physical Activity among Lean School Children in Rural Tanzania.” BMC Public Health, vol. 22, no. 1, 933, Springer Science and Business Media LLC, 2022, doi:10.1186/s12889-022-12949-9. short: C. Ludwig, N. Knoll-Pientka, A. Mwanri, C. Erfle, V. Onywera, M.S. Tremblay, J. Bühlmeier, A. Luzak, M. Ferland, H. Schulz, L. Libuda, J. Hebebrand, BMC Public Health 22 (2022). date_created: 2022-09-15T09:21:56Z date_updated: 2022-10-27T08:37:03Z department: - _id: '35' - _id: '17' doi: 10.1186/s12889-022-12949-9 extern: '1' intvolume: ' 22' issue: '1' keyword: - Public Health - Environmental and Occupational Health language: - iso: eng publication: BMC Public Health publication_identifier: issn: - 1471-2458 publication_status: published publisher: Springer Science and Business Media LLC status: public title: Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania type: journal_article user_id: '14931' volume: 22 year: '2022' ... --- _id: '33386' abstract: - lang: eng text: "Abstract\r\n Background/objectives\r\n \ The transition to adolescence is characterised by considerable behavioural changes, including diet. This study describes the level of obesogenic eating behaviours in 10- and 15-year-olds, and their association with dietary intake.\r\n \r\n Subjects/methods\r\n \ Participants of the 10- and 15-year follow-ups of the German GINIplus and LISA birth cohort studies were included (N10 = 2257; N15 = 1880). Eating behaviours and dietary intake were assessed via self-report questionnaires. Sex-stratified, cross-sectional associations of “external eating”, “emotional eating” and “dietary restraint” (the latter at age 15 years only) with dietary intake (17 food groups—categorised into tertiles, macronutrients, and total energy) were assessed using multinomial logistic or multiple linear regression as required, adjusting for covariates and correcting for multiple testing.\r\n \r\n Results\r\n \ Reported levels of eating behaviours were low in both age-groups. External eating was higher in 10-year-old males than females, while all eating behaviours were most pronounced in 15-year-old females. At 10 years, emotional eating was associated with medium vegetable intake in females (Relative Risk Ratio (RRR) = 1.84, p = 0.0017). At 15 years, external eating was associated with total energy (kJ) in females (β = 718, p = 0.0002) and high butter intake in males (RRR = 1.96, p = 0.0019). Dietary restraint in females was inversely associated with total energy (β = −967, p < 0.0001) and omega-3 fatty acids (Means Ratio (MR) = 0.94, p = 0.0017), and positively associated with high fruit (RRR = 2.20, p = 0.0003) and whole grains (RRR = 1.94, p = 0.0013).\r\n \ \r\n Conclusion\r\n \ Obesogenic eating behaviour scores are low among children and adolescents of a predominantly high socioeconomic status population and present only few associations with specific aspects of diet, mainly among adolescent females.\r\n \ " author: - first_name: Anne full_name: Marb, Anne last_name: Marb - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Marie full_name: Standl, Marie last_name: Standl - first_name: Sibylle full_name: Koletzko, Sibylle last_name: Koletzko - first_name: Carl-Peter full_name: Bauer, Carl-Peter last_name: Bauer - first_name: Tamara full_name: Schikowski, Tamara last_name: Schikowski - first_name: Dietrich full_name: Berdel, Dietrich last_name: Berdel - first_name: Andrea full_name: von Berg, Andrea last_name: von Berg - first_name: Gunda full_name: Herberth, Gunda last_name: Herberth - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Carla P. full_name: Harris, Carla P. last_name: Harris citation: ama: 'Marb A, Libuda L, Standl M, et al. Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies. European Journal of Clinical Nutrition. Published online 2022. doi:10.1038/s41430-022-01125-2' apa: 'Marb, A., Libuda, L., Standl, M., Koletzko, S., Bauer, C.-P., Schikowski, T., Berdel, D., von Berg, A., Herberth, G., Bühlmeier, J., & Harris, C. P. (2022). Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies. European Journal of Clinical Nutrition. https://doi.org/10.1038/s41430-022-01125-2' bibtex: '@article{Marb_Libuda_Standl_Koletzko_Bauer_Schikowski_Berdel_von Berg_Herberth_Bühlmeier_et al._2022, title={Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies}, DOI={10.1038/s41430-022-01125-2}, journal={European Journal of Clinical Nutrition}, publisher={Springer Science and Business Media LLC}, author={Marb, Anne and Libuda, Lars and Standl, Marie and Koletzko, Sibylle and Bauer, Carl-Peter and Schikowski, Tamara and Berdel, Dietrich and von Berg, Andrea and Herberth, Gunda and Bühlmeier, Judith and et al.}, year={2022} }' chicago: 'Marb, Anne, Lars Libuda, Marie Standl, Sibylle Koletzko, Carl-Peter Bauer, Tamara Schikowski, Dietrich Berdel, et al. “Obesogenic Eating Behaviour and Dietary Intake in German Children and Adolescents: Results from the GINIplus and LISA Birth Cohort Studies.” European Journal of Clinical Nutrition, 2022. https://doi.org/10.1038/s41430-022-01125-2.' ieee: 'A. Marb et al., “Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies,” European Journal of Clinical Nutrition, 2022, doi: 10.1038/s41430-022-01125-2.' mla: 'Marb, Anne, et al. “Obesogenic Eating Behaviour and Dietary Intake in German Children and Adolescents: Results from the GINIplus and LISA Birth Cohort Studies.” European Journal of Clinical Nutrition, Springer Science and Business Media LLC, 2022, doi:10.1038/s41430-022-01125-2.' short: A. Marb, L. Libuda, M. Standl, S. Koletzko, C.-P. Bauer, T. Schikowski, D. Berdel, A. von Berg, G. Herberth, J. Bühlmeier, C.P. Harris, European Journal of Clinical Nutrition (2022). date_created: 2022-09-15T09:25:50Z date_updated: 2022-10-27T08:34:52Z department: - _id: '17' - _id: '36' doi: 10.1038/s41430-022-01125-2 extern: '1' keyword: - Nutrition and Dietetics - Medicine (miscellaneous) language: - iso: eng publication: European Journal of Clinical Nutrition publication_identifier: issn: - 0954-3007 - 1476-5640 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies' type: journal_article user_id: '14931' year: '2022' ... --- _id: '35311' author: - first_name: K full_name: Jansen, K last_name: Jansen - first_name: J full_name: Tempes, J last_name: Tempes - first_name: A full_name: Drozdowska, A last_name: Drozdowska - first_name: M full_name: Gutmann, M last_name: Gutmann - first_name: M full_name: Falkenstein, M last_name: Falkenstein - first_name: Anette full_name: Buyken, Anette id: '65985' last_name: Buyken - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: H full_name: Rudolf, H last_name: Rudolf - first_name: T full_name: Lücke, T last_name: Lücke - first_name: M full_name: Kersting, M last_name: Kersting citation: ama: 'Jansen K, Tempes J, Drozdowska A, et al. Correction: Short-term effects of carbohydrates differing in glycemic index (GI) consumed at lunch on children’s cognitive function in a randomized crossover study. Eur J Clin Nutr. 2022;76(5):779.' apa: 'Jansen, K., Tempes, J., Drozdowska, A., Gutmann, M., Falkenstein, M., Buyken, A., Libuda, L., Rudolf, H., Lücke, T., & Kersting, M. (2022). Correction: Short-term effects of carbohydrates differing in glycemic index (GI) consumed at lunch on children’s cognitive function in a randomized crossover study. Eur J Clin Nutr, 76(5), 779.' bibtex: '@article{Jansen_Tempes_Drozdowska_Gutmann_Falkenstein_Buyken_Libuda_Rudolf_Lücke_Kersting_2022, title={Correction: Short-term effects of carbohydrates differing in glycemic index (GI) consumed at lunch on children’s cognitive function in a randomized crossover study.}, volume={76}, number={5}, journal={Eur J Clin Nutr}, author={Jansen, K and Tempes, J and Drozdowska, A and Gutmann, M and Falkenstein, M and Buyken, Anette and Libuda, Lars and Rudolf, H and Lücke, T and Kersting, M}, year={2022}, pages={779} }' chicago: 'Jansen, K, J Tempes, A Drozdowska, M Gutmann, M Falkenstein, Anette Buyken, Lars Libuda, H Rudolf, T Lücke, and M Kersting. “Correction: Short-Term Effects of Carbohydrates Differing in Glycemic Index (GI) Consumed at Lunch on Children’s Cognitive Function in a Randomized Crossover Study.” Eur J Clin Nutr 76, no. 5 (2022): 779.' ieee: 'K. Jansen et al., “Correction: Short-term effects of carbohydrates differing in glycemic index (GI) consumed at lunch on children’s cognitive function in a randomized crossover study.,” Eur J Clin Nutr, vol. 76, no. 5, p. 779, 2022.' mla: 'Jansen, K., et al. “Correction: Short-Term Effects of Carbohydrates Differing in Glycemic Index (GI) Consumed at Lunch on Children’s Cognitive Function in a Randomized Crossover Study.” Eur J Clin Nutr, vol. 76, no. 5, 2022, p. 779.' short: K. Jansen, J. Tempes, A. Drozdowska, M. Gutmann, M. Falkenstein, A. Buyken, L. Libuda, H. Rudolf, T. Lücke, M. Kersting, Eur J Clin Nutr 76 (2022) 779. date_created: 2023-01-05T16:44:01Z date_updated: 2023-01-05T16:48:06Z department: - _id: '35' - _id: '17' - _id: '22' - _id: '571' - _id: '395' external_id: pmid: - '34837056' intvolume: ' 76' issue: '5' language: - iso: eng page: '779' pmid: '1' publication: Eur J Clin Nutr publication_identifier: issn: - 0954-3007 - 1476-5640 status: public title: 'Correction: Short-term effects of carbohydrates differing in glycemic index (GI) consumed at lunch on children''s cognitive function in a randomized crossover study.' type: journal_article user_id: '61597' volume: 76 year: '2022' ... --- _id: '32327' abstract: - lang: eng text: 'AbstractThere is preliminary evidence that adrenal steroids other than cortisol may be valuable biomarkers for major depressive disorder (MDD). So far, studies have been conducted in adults only, and conclusions are limited, mainly due to small sample sizes. Therefore, the present study assessed whether adrenal steroids serve as biomarkers for adolescent MDD. In 261 depressed adolescents (170 females) treated at a single psychiatric hospital, serum adrenal steroids (progesterone, 17-hydroxyprogesterone, 21-deoxycortisol, 11-deoxycortisol, cortisol, cortisone, deoxycorticosterone, corticosterone) were determined by liquid chromatography-tandem mass spectrometry. Findings were compared to that of an age- and sex-matched reference cohort (N = 255) by nonparametric analysis of variance. Nonparametric receiver operating characteristics (ROC) analyses were conducted to evaluate the diagnostic performance of single steroids and steroid ratios to classify depression status. Sensitivity analyses considered important confounders of adrenal functioning, and ROC results were verified by cross-validation. Compared to the reference cohort, levels of deoxycorticosterone and 21-deoxycortisol were decreased (P < 0.001). All other glucocorticoid- and mineralocorticoid-related steroids were increased (P < 0.001). The corticosterone to deoxycorticosterone ratio evidenced excellent classification characteristics, especially in females (AUC: 0.957; sensitivity: 0.902; specificity: 0.891). The adrenal steroid metabolome qualifies as a bio-readout reflecting adolescent MDD by a distinct steroid pattern that indicates dysfunction of the hypothalamus–pituitary–adrenal axis. Moreover, the corticosterone to deoxycorticosterone ratio may prospectively qualify to contribute to precision medicine in psychiatry by identifying those patients who might benefit from antiglucocorticoid treatment or those at risk for recurrence when adrenal dysfunction has not resolved.' article_number: '255' author: - first_name: Raphael full_name: Hirtz, Raphael last_name: Hirtz - first_name: Lars full_name: Libuda, Lars id: '88682' last_name: Libuda orcid: 0000-0003-1603-3133 - first_name: Anke full_name: Hinney, Anke last_name: Hinney - first_name: Manuel full_name: Föcker, Manuel last_name: Föcker - first_name: Judith full_name: Bühlmeier, Judith id: '89838' last_name: Bühlmeier - first_name: Paul-Martin full_name: Holterhus, Paul-Martin last_name: Holterhus - first_name: Alexandra full_name: Kulle, Alexandra last_name: Kulle - first_name: Cordula full_name: Kiewert, Cordula last_name: Kiewert - first_name: Berthold P. full_name: Hauffa, Berthold P. last_name: Hauffa - first_name: Johannes full_name: Hebebrand, Johannes last_name: Hebebrand - first_name: Corinna full_name: Grasemann, Corinna last_name: Grasemann citation: ama: 'Hirtz R, Libuda L, Hinney A, et al. The adrenal steroid profile in adolescent depression: a valuable bio-readout? Translational Psychiatry. 2022;12(1). doi:10.1038/s41398-022-01966-2' apa: 'Hirtz, R., Libuda, L., Hinney, A., Föcker, M., Bühlmeier, J., Holterhus, P.-M., Kulle, A., Kiewert, C., Hauffa, B. P., Hebebrand, J., & Grasemann, C. (2022). The adrenal steroid profile in adolescent depression: a valuable bio-readout? Translational Psychiatry, 12(1), Article 255. https://doi.org/10.1038/s41398-022-01966-2' bibtex: '@article{Hirtz_Libuda_Hinney_Föcker_Bühlmeier_Holterhus_Kulle_Kiewert_Hauffa_Hebebrand_et al._2022, title={The adrenal steroid profile in adolescent depression: a valuable bio-readout?}, volume={12}, DOI={10.1038/s41398-022-01966-2}, number={1255}, journal={Translational Psychiatry}, publisher={Springer Science and Business Media LLC}, author={Hirtz, Raphael and Libuda, Lars and Hinney, Anke and Föcker, Manuel and Bühlmeier, Judith and Holterhus, Paul-Martin and Kulle, Alexandra and Kiewert, Cordula and Hauffa, Berthold P. and Hebebrand, Johannes and et al.}, year={2022} }' chicago: 'Hirtz, Raphael, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, et al. “The Adrenal Steroid Profile in Adolescent Depression: A Valuable Bio-Readout?” Translational Psychiatry 12, no. 1 (2022). https://doi.org/10.1038/s41398-022-01966-2.' ieee: 'R. Hirtz et al., “The adrenal steroid profile in adolescent depression: a valuable bio-readout?,” Translational Psychiatry, vol. 12, no. 1, Art. no. 255, 2022, doi: 10.1038/s41398-022-01966-2.' mla: 'Hirtz, Raphael, et al. “The Adrenal Steroid Profile in Adolescent Depression: A Valuable Bio-Readout?” Translational Psychiatry, vol. 12, no. 1, 255, Springer Science and Business Media LLC, 2022, doi:10.1038/s41398-022-01966-2.' short: R. Hirtz, L. Libuda, A. Hinney, M. Föcker, J. Bühlmeier, P.-M. Holterhus, A. Kulle, C. Kiewert, B.P. Hauffa, J. Hebebrand, C. Grasemann, Translational Psychiatry 12 (2022). date_created: 2022-07-06T15:14:39Z date_updated: 2023-01-06T11:48:51Z department: - _id: '35' doi: 10.1038/s41398-022-01966-2 intvolume: ' 12' issue: '1' keyword: - Biological Psychiatry - Cellular and Molecular Neuroscience - Psychiatry and Mental health language: - iso: eng publication: Translational Psychiatry publication_identifier: issn: - 2158-3188 publication_status: published publisher: Springer Science and Business Media LLC status: public title: 'The adrenal steroid profile in adolescent depression: a valuable bio-readout?' type: journal_article user_id: '88682' volume: 12 year: '2022' ...