---
_id: '65374'
article_number: '109'
author:
- first_name: Laura
full_name: Schlarbaum, Laura
id: '96697'
last_name: Schlarbaum
- first_name: Nicole
full_name: Jankovic, Nicole
id: '105192'
last_name: Jankovic
orcid: https://orcid.org/0000-0002-9235-5356
- first_name: Judith
full_name: Bühlmeier, Judith
id: '89838'
last_name: Bühlmeier
- first_name: Eva
full_name: Hohoff, Eva
last_name: Hohoff
- first_name: Rhea
full_name: Dankers, Rhea
id: '64668'
last_name: Dankers
- first_name: Harald
full_name: Engler, Harald
last_name: Engler
- first_name: Raphael
full_name: Hirtz, Raphael
last_name: Hirtz
- first_name: Denise
full_name: Zwanziger, Denise
last_name: Zwanziger
- first_name: Corinna
full_name: Grasemann, Corinna
last_name: Grasemann
- first_name: Triinu
full_name: Peters, Triinu
last_name: Peters
- first_name: Anke
full_name: Hinney, Anke
last_name: Hinney
- first_name: Jochen
full_name: Antel, Jochen
last_name: Antel
- first_name: Manuel
full_name: Föcker, Manuel
last_name: Föcker
- first_name: Lars
full_name: Libuda, Lars
id: '88682'
last_name: Libuda
orcid: 0000-0003-1603-3133
citation:
ama: Schlarbaum L, Jankovic N, Bühlmeier J, et al. Does inflammation moderate the
effect of vitamin D supplementation on depressive symptoms? Results of an interventional
study in children and adolescents. European Journal of Nutrition. 2026;65(3).
doi:10.1007/s00394-026-03920-0
apa: Schlarbaum, L., Jankovic, N., Bühlmeier, J., Hohoff, E., Dankers, R., Engler,
H., Hirtz, R., Zwanziger, D., Grasemann, C., Peters, T., Hinney, A., Antel, J.,
Föcker, M., & Libuda, L. (2026). Does inflammation moderate the effect of
vitamin D supplementation on depressive symptoms? Results of an interventional
study in children and adolescents. European Journal of Nutrition, 65(3),
Article 109. https://doi.org/10.1007/s00394-026-03920-0
bibtex: '@article{Schlarbaum_Jankovic_Bühlmeier_Hohoff_Dankers_Engler_Hirtz_Zwanziger_Grasemann_Peters_et
al._2026, title={Does inflammation moderate the effect of vitamin D supplementation
on depressive symptoms? Results of an interventional study in children and adolescents},
volume={65}, DOI={10.1007/s00394-026-03920-0},
number={3109}, journal={European Journal of Nutrition}, publisher={Springer Science
and Business Media LLC}, author={Schlarbaum, Laura and Jankovic, Nicole and Bühlmeier,
Judith and Hohoff, Eva and Dankers, Rhea and Engler, Harald and Hirtz, Raphael
and Zwanziger, Denise and Grasemann, Corinna and Peters, Triinu and et al.}, year={2026}
}'
chicago: Schlarbaum, Laura, Nicole Jankovic, Judith Bühlmeier, Eva Hohoff, Rhea
Dankers, Harald Engler, Raphael Hirtz, et al. “Does Inflammation Moderate the
Effect of Vitamin D Supplementation on Depressive Symptoms? Results of an Interventional
Study in Children and Adolescents.” European Journal of Nutrition 65, no.
3 (2026). https://doi.org/10.1007/s00394-026-03920-0.
ieee: 'L. Schlarbaum et al., “Does inflammation moderate the effect of vitamin
D supplementation on depressive symptoms? Results of an interventional study in
children and adolescents,” European Journal of Nutrition, vol. 65, no.
3, Art. no. 109, 2026, doi: 10.1007/s00394-026-03920-0.'
mla: Schlarbaum, Laura, et al. “Does Inflammation Moderate the Effect of Vitamin
D Supplementation on Depressive Symptoms? Results of an Interventional Study in
Children and Adolescents.” European Journal of Nutrition, vol. 65, no.
3, 109, Springer Science and Business Media LLC, 2026, doi:10.1007/s00394-026-03920-0.
short: L. Schlarbaum, N. Jankovic, J. Bühlmeier, E. Hohoff, R. Dankers, H. Engler,
R. Hirtz, D. Zwanziger, C. Grasemann, T. Peters, A. Hinney, J. Antel, M. Föcker,
L. Libuda, European Journal of Nutrition 65 (2026).
date_created: 2026-04-08T09:04:52Z
date_updated: 2026-04-15T08:57:13Z
ddc:
- '570'
doi: 10.1007/s00394-026-03920-0
file:
- access_level: closed
content_type: application/pdf
creator: laura36
date_created: 2026-04-08T09:15:10Z
date_updated: 2026-04-08T09:15:10Z
file_id: '65377'
file_name: 394_2026_Article_3920.pdf
file_size: 939647
relation: main_file
success: 1
file_date_updated: 2026-04-08T09:15:10Z
has_accepted_license: '1'
intvolume: ' 65'
issue: '3'
language:
- iso: eng
publication: European Journal of Nutrition
publication_identifier:
issn:
- 1436-6207
- 1436-6215
publication_status: published
publisher: Springer Science and Business Media LLC
status: public
title: Does inflammation moderate the effect of vitamin D supplementation on depressive
symptoms? Results of an interventional study in children and adolescents
type: journal_article
user_id: '96697'
volume: 65
year: '2026'
...
---
_id: '65375'
abstract:
- lang: eng
text: "Abstract\r\n Vitamin D
has been associated with depression, potentially via anti-inflammatory mechanisms,
yet data is scarce, particularly in adolescence. We investigated (1) whether lower
vitamin D status is associated with greater depression severity and (2) whether
this association is statistically moderated by inflammation in patients of a child
and adolescent psychiatry department. At admission fasting morning venous blood
was drawn. Serum vitamin D (25(OH)D) and C-reactive protein (CRP) were analyzed
in all participants [n=465 (64.7%♀; 11.3-18.9 years)]. In a subsample [n=177],
we additionally measured tumor necrosis factor-alpha, interferon-gamma and interleukin
(IL)-1β, IL-6, IL-8, IL-10. Depression severity was assessed by the Beck Depression
Inventory-II (BDI-II) [n=450], the Diagnostic System for Mental Disorders in Childhood
and Adolescence via self-assessment (DISYPS Self) [n=441], and parent-assessment
(DISYPS Proxy) [n=422]. Overall, 43.2% [n=201] were at risk for vitamin D deficiency
(<30nmol/L), and 73.5%-83.2% –depending on assessment tool– showed at least
mild depression. Linear regression revealed an inverse association between 25(OH)D
and BDI-II in both crude and CRP-adjusted full-sample models. Logistic regressions
showed a robust inverse association between 25(OH)D and DISYPS Proxy, but not
for DISYPS Self. Although 25(OH)D was inversely correlated with some pro-inflammatory
markers, neither their inclusion in regression models nor formal mediation analyses
supported inflammation as a mediator of the vitamin D–depression association.
Overall, our results suggest that vitamin D relates modestly to both depression
and inflammation in adolescence. However, based on the measured parameters, we
cannot confirm that anti-inflammatory effects are the link between vitamin D and
depression."
article_type: original
author:
- first_name: Laura
full_name: Schlarbaum, Laura
id: '96697'
last_name: Schlarbaum
- first_name: Nicole
full_name: Jankovic, Nicole
id: '105192'
last_name: Jankovic
orcid: https://orcid.org/0000-0002-9235-5356
- first_name: Judith
full_name: Bühlmeier, Judith
id: '89838'
last_name: Bühlmeier
- first_name: Harald
full_name: Engler, Harald
last_name: Engler
- first_name: Raphael
full_name: Hirtz, Raphael
last_name: Hirtz
- first_name: Corinna
full_name: Grasemann, Corinna
last_name: Grasemann
- first_name: Triinu
full_name: Peters, Triinu
last_name: Peters
- first_name: Anke
full_name: Hinney, Anke
last_name: Hinney
- first_name: Jochen
full_name: Antel, Jochen
last_name: Antel
- first_name: Johannes
full_name: Hebebrand, Johannes
last_name: Hebebrand
- first_name: Manuel
full_name: Föcker, Manuel
last_name: Föcker
- first_name: Lars
full_name: Libuda, Lars
id: '88682'
last_name: Libuda
orcid: 0000-0003-1603-3133
citation:
ama: Schlarbaum L, Jankovic N, Bühlmeier J, et al. Does inflammation explain the
association between vitamin D and depression? Results of a cross-sectional study
in children and adolescents. British Journal of Nutrition. Published online
2026:1-37. doi:10.1017/s0007114526106928
apa: Schlarbaum, L., Jankovic, N., Bühlmeier, J., Engler, H., Hirtz, R., Grasemann,
C., Peters, T., Hinney, A., Antel, J., Hebebrand, J., Föcker, M., & Libuda,
L. (2026). Does inflammation explain the association between vitamin D and depression?
Results of a cross-sectional study in children and adolescents. British Journal
of Nutrition, 1–37. https://doi.org/10.1017/s0007114526106928
bibtex: '@article{Schlarbaum_Jankovic_Bühlmeier_Engler_Hirtz_Grasemann_Peters_Hinney_Antel_Hebebrand_et
al._2026, title={Does inflammation explain the association between vitamin D and
depression? Results of a cross-sectional study in children and adolescents}, DOI={10.1017/s0007114526106928},
journal={British Journal of Nutrition}, publisher={Cambridge University Press
(CUP)}, author={Schlarbaum, Laura and Jankovic, Nicole and Bühlmeier, Judith and
Engler, Harald and Hirtz, Raphael and Grasemann, Corinna and Peters, Triinu and
Hinney, Anke and Antel, Jochen and Hebebrand, Johannes and et al.}, year={2026},
pages={1–37} }'
chicago: Schlarbaum, Laura, Nicole Jankovic, Judith Bühlmeier, Harald Engler, Raphael
Hirtz, Corinna Grasemann, Triinu Peters, et al. “Does Inflammation Explain the
Association between Vitamin D and Depression? Results of a Cross-Sectional Study
in Children and Adolescents.” British Journal of Nutrition, 2026, 1–37.
https://doi.org/10.1017/s0007114526106928.
ieee: 'L. Schlarbaum et al., “Does inflammation explain the association between
vitamin D and depression? Results of a cross-sectional study in children and adolescents,”
British Journal of Nutrition, pp. 1–37, 2026, doi: 10.1017/s0007114526106928.'
mla: Schlarbaum, Laura, et al. “Does Inflammation Explain the Association between
Vitamin D and Depression? Results of a Cross-Sectional Study in Children and Adolescents.”
British Journal of Nutrition, Cambridge University Press (CUP), 2026, pp.
1–37, doi:10.1017/s0007114526106928.
short: L. Schlarbaum, N. Jankovic, J. Bühlmeier, H. Engler, R. Hirtz, C. Grasemann,
T. Peters, A. Hinney, J. Antel, J. Hebebrand, M. Föcker, L. Libuda, British Journal
of Nutrition (2026) 1–37.
date_created: 2026-04-08T09:06:17Z
date_updated: 2026-04-28T14:24:58Z
ddc:
- '570'
doi: 10.1017/s0007114526106928
file:
- access_level: closed
content_type: application/pdf
creator: laura36
date_created: 2026-04-28T14:24:22Z
date_updated: 2026-04-28T14:24:22Z
file_id: '65504'
file_name: does-inflammation-explain-the-association-between-vitamin-d-and-depression-results-of-a-cross-sectional-study-in-children-and-adolescents.pdf
file_size: 715441
relation: main_file
success: 1
file_date_updated: 2026-04-28T14:24:22Z
has_accepted_license: '1'
language:
- iso: eng
page: 1-37
publication: British Journal of Nutrition
publication_identifier:
issn:
- 0007-1145
- 1475-2662
publication_status: published
publisher: Cambridge University Press (CUP)
status: public
title: Does inflammation explain the association between vitamin D and depression?
Results of a cross-sectional study in children and adolescents
type: journal_article
user_id: '96697'
year: '2026'
...
---
_id: '53788'
abstract:
- lang: eng
text: 'Globally, an unbalanced diet causes more deaths than any other factor.
Due to a lack of knowledge, it is difficult for consumers to select healthy foods
at the point of sale. Although different front-of-pack labeling schemes exist,
their informative value is limited due to small sets of considered parameters
and lacking information on ingredient composition. We developed and evalauated
a manufacture-independent approach to quantify ingredient composition of 294 ready-to
eat salads (distinguished into 73 subgroups) as test set. Nutritional quality
was assessed by the nutriRECIPE-Index and compared to the Nutri-Score. The nutriRECIPE-Index
comprises the calculation of energy-adjusted nutrient density of 16 desirable
and three undesirable nutrients, which are weighted according to their degree
of supply in the population. We show that the nutriRECIPE-Index has stronger discriminatory
power compared to the Nutri-Score and discriminates as well or even better in
63 out of the 73 subgroups. This was evident in groups where seemingly similar
products were compared, e.g., potato salads (Nutri-Score: C only, nutriRECIPE-Index:
B, C and D). Moreover, the nutriRECIPE-Index is adjustable to any target population’s
specific needs and supply situation, such as seniors, and children. Hence, a more
sophisticated distinction between single food products is possible using the nutriRECIPE-Index.'
article_number: '4011'
author:
- first_name: Laura
full_name: Schlarbaum, Laura
id: '96697'
last_name: Schlarbaum
- first_name: Frank
full_name: Forner, Frank
last_name: Forner
- first_name: Kristin
full_name: Bohn, Kristin
last_name: Bohn
- first_name: Michael
full_name: Amberg, Michael
last_name: Amberg
- first_name: Patrick
full_name: Mäder, Patrick
last_name: Mäder
- first_name: Stefan
full_name: Lorkowski, Stefan
last_name: Lorkowski
- first_name: Toni
full_name: Meier, Toni
last_name: Meier
citation:
ama: 'Schlarbaum L, Forner F, Bohn K, et al. Nutritional Assessment of Ready-to-Eat
Salads in German Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score.
Foods. 2022;11(24). doi:10.3390/foods11244011'
apa: 'Schlarbaum, L., Forner, F., Bohn, K., Amberg, M., Mäder, P., Lorkowski, S.,
& Meier, T. (2022). Nutritional Assessment of Ready-to-Eat Salads in German
Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score. Foods,
11(24), Article 4011. https://doi.org/10.3390/foods11244011'
bibtex: '@article{Schlarbaum_Forner_Bohn_Amberg_Mäder_Lorkowski_Meier_2022, title={Nutritional
Assessment of Ready-to-Eat Salads in German Supermarkets: Comparison of the nutriRECIPE-Index
and the Nutri-Score}, volume={11}, DOI={10.3390/foods11244011},
number={244011}, journal={Foods}, publisher={MDPI AG}, author={Schlarbaum, Laura
and Forner, Frank and Bohn, Kristin and Amberg, Michael and Mäder, Patrick and
Lorkowski, Stefan and Meier, Toni}, year={2022} }'
chicago: 'Schlarbaum, Laura, Frank Forner, Kristin Bohn, Michael Amberg, Patrick
Mäder, Stefan Lorkowski, and Toni Meier. “Nutritional Assessment of Ready-to-Eat
Salads in German Supermarkets: Comparison of the NutriRECIPE-Index and the Nutri-Score.”
Foods 11, no. 24 (2022). https://doi.org/10.3390/foods11244011.'
ieee: 'L. Schlarbaum et al., “Nutritional Assessment of Ready-to-Eat Salads
in German Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score,”
Foods, vol. 11, no. 24, Art. no. 4011, 2022, doi: 10.3390/foods11244011.'
mla: 'Schlarbaum, Laura, et al. “Nutritional Assessment of Ready-to-Eat Salads in
German Supermarkets: Comparison of the NutriRECIPE-Index and the Nutri-Score.”
Foods, vol. 11, no. 24, 4011, MDPI AG, 2022, doi:10.3390/foods11244011.'
short: L. Schlarbaum, F. Forner, K. Bohn, M. Amberg, P. Mäder, S. Lorkowski, T.
Meier, Foods 11 (2022).
date_created: 2024-04-29T11:51:14Z
date_updated: 2026-04-08T09:17:11Z
ddc:
- '570'
doi: 10.3390/foods11244011
file:
- access_level: closed
content_type: application/pdf
creator: laura36
date_created: 2026-04-08T09:16:34Z
date_updated: 2026-04-08T09:16:34Z
file_id: '65378'
file_name: foods-11-04011.pdf
file_size: 1958241
relation: main_file
success: 1
file_date_updated: 2026-04-08T09:16:34Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '24'
language:
- iso: eng
publication: Foods
publication_identifier:
issn:
- 2304-8158
publication_status: published
publisher: MDPI AG
status: public
title: 'Nutritional Assessment of Ready-to-Eat Salads in German Supermarkets: Comparison
of the nutriRECIPE-Index and the Nutri-Score'
type: journal_article
user_id: '96697'
volume: 11
year: '2022'
...