@inproceedings{25755, author = {{Moritzer, Elmar and Wittke, M.}}, booktitle = {{77th Annual Technical Conference of the Society of Plastics Engineers (ANTEC)}}, location = {{Detroit (USA)}}, title = {{{Simulation-based Optimization of Advanced Mixing Elements on Single Screw Extruders}}}, year = {{2019}}, } @inproceedings{25756, author = {{Moritzer, Elmar and Kartelmeyer, S. and Hüttemann, B. and Jaroschek, C.}}, booktitle = {{26. Fachtagung über Verarbeitung und Anwendung von Polymeren}}, location = {{Chemnitz (Deutschland)}}, title = {{{Spritzgießwerkzeuge mit Heatpipe-Temperierung}}}, year = {{2019}}, } @article{25757, author = {{Moritzer, Elmar and Jilg, J. and Sibbe, N.}}, journal = {{PU MAGAZIN}}, pages = {{220--224}}, title = {{{Untersuchung der Verbundhaftung zwischen spritzgegossenen TPUs und einer reaktiven, gießfähigen Polyurethanmasse}}}, year = {{2019}}, } @inproceedings{25759, author = {{Schöppner, Volker and Westhues, K.}}, booktitle = {{VDI Wissensforum}}, location = {{Stuttgart (Deutschland)}}, title = {{{Vortrag „Aufschmelzen“ Optimierter Betrieb und Scale-up von Doppelschnecken-Extrudern}}}, year = {{2019}}, } @inproceedings{25760, author = {{Moritzer, Elmar and Jilg, J.}}, booktitle = {{26. Fachtagung über Verarbeitung und Anwendung von Polymeren}}, isbn = {{978-3-939382-14-0}}, location = {{Chemnitz (Deutschland)}}, title = {{{Zur Wirkung dehnströmungsinduzierender Spritzgießdüsen für glasfaserverstärktes Polypropylen im Sonderverfahren der Spritzgießdirektcompoundierung (SGDC)}}}, year = {{2019}}, } @article{26015, author = {{Büchel, Daniel and Jakobsmeyer, Rasmus and Döring, Michael and Adams, Michael and Rückert, Ulrich and Baumeister, Jochen}}, issn = {{2474-8668}}, journal = {{International Journal of Performance Analysis in Sport}}, pages = {{832--844}}, title = {{{Effect of playing position and time on-court on activity profiles in german elite team handball}}}, doi = {{10.1080/24748668.2019.1663071}}, year = {{2019}}, } @inbook{26098, abstract = {{Since, in the presence of humidity the inter-particle processes are dominated by capillary forces, a fundamental understanding of the water adsorption and the capillary bridge formation is very important. However, the adsorbed water structure and thus the capillary bridge formation is influenced by various parameters like the particle morphology (e.g. particle size, roughness) as well as the surface chemistry (surface energy, adsorbate structure) and therefore needs to be analyzed on a submicroscopic or even molecular basis. A multi-scale approach ranging from experiments on an individual particle level (AFM and liquid bridge simulation) and investigations on small particle ensembles (combined QCM-D/FTIR) up to macroscopic description of bulk behavior is presented in this chapter. In this context, the combined in situ QCM-D/FTIR experiments are bridging the gap between experiments on an individual particle level and macroscopic bulk behavior. Variation of surface chemistry by means of adsorption of functional organic molecules allows for the correlation of macroscopic particle behavior to nanoscopic effects like the presence and structure of adsorbate layers as well as the formation of capillary bridges while keeping the disperse properties constant. Besides extensive experimental work, simulations of capillary bridges formed by condensation from humid air are presented. It is clearly shown that well known approximations which have been introduced for micron-sized particles are not valid any more for nano-scaled particles. The forces between nanoparticles by static liquid bridges and their dependency on particle size, contact angle, humidity and interparticle distance are discussed in detail. Furthermore, capillary forces during separation of particles are studied thoroughly and a constitutive law based on a contact stiffness allows the transfer to DEM simulations of wet powders. Finally, it is demonstrated by comparison to Molecular Dynamics simulations, that the used continuum approach to simulate capillary bridges might even be used down to particle sizes of a few nanometers, if some additional effects are considered correctly.}}, author = {{Schmid, Hans-Joachim and Grundmeier, Guido and Dörmann, Michael and Orive, Alejandro González and de los Arcos, Teresa and Torun, Boray}}, booktitle = {{Particles in Contact}}, title = {{{Understanding and Manipulation of Nanoparticle Contact Forces by Capillary Bridges}}}, doi = {{10.1007/978-3-030-15899-6_2}}, year = {{2019}}, } @article{26224, author = {{Santandrea, Matteo and Stefszky, Michael and Roeland, Ganaël and Silberhorn, Christine}}, issn = {{1367-2630}}, journal = {{New Journal of Physics}}, title = {{{Characterisation of fabrication inhomogeneities in Ti:LiNbO3 waveguides}}}, doi = {{10.1088/1367-2630/ab5cb5}}, year = {{2019}}, } @article{26225, author = {{Santandrea, Matteo and Stefszky, Michael and Silberhorn, Christine}}, issn = {{0146-9592}}, journal = {{Optics Letters}}, title = {{{General framework for the analysis of imperfections in nonlinear systems}}}, doi = {{10.1364/ol.44.005398}}, year = {{2019}}, } @article{26226, author = {{Santandrea, Matteo and Stefszky, Michael and Ansari, Vahid and Silberhorn, Christine}}, issn = {{1367-2630}}, journal = {{New Journal of Physics}}, title = {{{Fabrication limits of waveguides in nonlinear crystals and their impact on quantum optics applications}}}, doi = {{10.1088/1367-2630/aaff13}}, year = {{2019}}, } @article{26237, author = {{Luo, Kai-Hong and Ansari, Vahid and Massaro, Marcello and Santandrea, Matteo and Eigner, Christof and Ricken, Raimund and Herrmann, Harald and Silberhorn, Christine}}, issn = {{1094-4087}}, journal = {{Optics Express}}, title = {{{Counter-propagating photon pair generation in a nonlinear waveguide}}}, doi = {{10.1364/oe.378789}}, year = {{2019}}, } @article{26293, author = {{Sperling, Jan and Vogel, W}}, issn = {{0031-8949}}, journal = {{Physica Scripta}}, title = {{{Quasiprobability distributions for quantum-optical coherence and beyond}}}, doi = {{10.1088/1402-4896/ab5501}}, year = {{2019}}, } @article{26297, author = {{Cimini, Valeria and Gianani, Ilaria and Sbroscia, Marco and Sperling, Jan and Barbieri, Marco}}, issn = {{2643-1564}}, journal = {{Physical Review Research}}, title = {{{Measuring coherence of quantum measurements}}}, doi = {{10.1103/physrevresearch.1.033020}}, year = {{2019}}, } @article{26298, author = {{Rezai, Mohammad and Sperling, Jan and Gerhardt, Ilja}}, issn = {{2058-9565}}, journal = {{Quantum Science and Technology}}, title = {{{What can single photons do what lasers cannot do?}}}, doi = {{10.1088/2058-9565/ab3d56}}, year = {{2019}}, } @article{26299, author = {{Phillips, D. S. and Walschaers, M. and Renema, J. J. and Walmsley, I. A. and Treps, N. and Sperling, Jan}}, issn = {{2469-9926}}, journal = {{Physical Review A}}, title = {{{Benchmarking of Gaussian boson sampling using two-point correlators}}}, doi = {{10.1103/physreva.99.023836}}, year = {{2019}}, } @article{26500, author = {{Lorz, Lennart and Meyer-Scott, Evan and Nitsche, Thomas and Potoček, Václav and Gábris, Aurél and Barkhofen, Sonja and Jex, Igor and Silberhorn, Christine}}, issn = {{2643-1564}}, journal = {{Physical Review Research}}, title = {{{Photonic quantum walks with four-dimensional coins}}}, doi = {{10.1103/physrevresearch.1.033036}}, year = {{2019}}, } @article{26501, author = {{Kruse, Regina and Hamilton, Craig S. and Sansoni, Linda and Barkhofen, Sonja and Silberhorn, Christine and Jex, Igor}}, issn = {{2469-9926}}, journal = {{Physical Review A}}, title = {{{Detailed study of Gaussian boson sampling}}}, doi = {{10.1103/physreva.100.032326}}, year = {{2019}}, } @article{26508, author = {{Nitsche, Thomas and Geib, Tobias and Stahl, Christoph and Lorz, Lennart and Cedzich, Christopher and Barkhofen, Sonja and Werner, Reinhard F and Silberhorn, Christine}}, issn = {{1367-2630}}, journal = {{New Journal of Physics}}, title = {{{Eigenvalue measurement of topologically protected edge states in split-step quantum walks}}}, doi = {{10.1088/1367-2630/ab12fa}}, year = {{2019}}, } @article{26509, author = {{Tiedau, Johannes and Meyer-Scott, Evan and Nitsche, Thomas and Barkhofen, Sonja and Bartley, Tim J. and Silberhorn, Christine}}, issn = {{1094-4087}}, journal = {{Optics Express}}, title = {{{A high dynamic range optical detector for measuring single photons and bright light}}}, doi = {{10.1364/oe.27.000001}}, year = {{2019}}, } @book{26636, author = {{Görel, Gamze}}, isbn = {{9783658261740}}, pages = {{173}}, publisher = {{Springer}}, title = {{{Inklusiver Unterricht aus Sicht von Grundschullehrkräften. Die Bedeutung von persönlichen Ressourcen}}}, doi = {{10.1007/978-3-658-26175-7}}, year = {{2019}}, } @article{26640, author = {{Hellmich, Frank and Löper, Marwin Felix and Görel, Gamze}}, issn = {{1471-3802}}, journal = {{Journal of Research in Special Educational Needs}}, number = {{S1}}, pages = {{36--48}}, title = {{{The role of primary school teachers’ attitudes and self‐efficacy beliefs for everyday practices in inclusive classrooms – a study on the verification of the ‘Theory of Planned Behaviour’}}}, doi = {{10.1111/1471-3802.12476}}, volume = {{19}}, year = {{2019}}, } @inbook{26668, author = {{Hellmich, Frank and Löper, Marwin Felix and Hoya, Fabian Karl}}, booktitle = {{Lehrer. Bildung. Gestalten. Beiträge zur empirischen Forschung in der Lehrerbildung }}, editor = {{Ehmke, Timo and Kuhl, Poldi and Pietsch, Marcus}}, pages = {{57--70}}, publisher = {{Beltz}}, title = {{{Unterscheiden sich Studentinnen und Studenten des Lehramts an Grund- und Förderschulen in ihren Einstellungen und ihren Selbstwirksamkeitsüberzeugungen in Bezug auf den inklusiven Unterricht? }}}, year = {{2019}}, } @article{26706, author = {{Hellmich, Frank and Löper, Marwin Felix}}, issn = {{0952-3383}}, journal = {{British Journal of Special Education}}, number = {{2}}, pages = {{157--179}}, title = {{{Children’s attitudes towards peers with learning disabilities - the role of perceived parental behaviour, contact experiences and self-efficacy beliefs}}}, doi = {{10.1111/1467-8578.12259}}, volume = {{46}}, year = {{2019}}, } @book{26723, editor = {{Schwab, Susanne and Nel, Mirna and Hellmich, Frank}}, publisher = {{Taylor & Francis/Routledge}}, title = {{{Social Participation of Students with Special Educational Needs in Mainstream Education}}}, year = {{2019}}, } @phdthesis{26898, abstract = {{Im Rahmen dieser Arbeit wurden die mikrostrukturelle Entwicklung und die daraus resultierenden mechanischen Eigenschaften der im SLM® Verfahren (Selective Laser Melting) verarbeiteten Nickelbasis-Superlegierung Inconel 718 untersucht. Anschließend wurde der Einfluss des HIP-Prozesses (Heißisostatisches Pressen) auf die Porosität, die Mikrostruktur und die mechanischen Eigenschaften analysiert. Da der HIP-Prozess oberflächennahe Poren nicht schließen kann, wurden ausgewählte Proben durch das Arc-PVD-Verfahren (Physical Vapor Deposition) mit einer Ni-20Cr Beschichtung gekapselt. Da die typischen Zellstrukturen zusammen mit den γ´´- Ausscheidungen nach dem Lösungsglühen mit anschließender Ausscheidungshärtung auftreten, konnte die höchste Streckgrenze (Rp0,2) unter quasistatischer Belastung bei Raumtemperatur (RT) sowie bei 650 °C ermittelt werden. Unter zyklischer Belastung zeigen die beschichteten und heißisostatisch gepressten Proben die geringste Ermüdungsfestigkeit bei RT, sowohl vor als auch nach der Ausscheidungshärtung. Im lösungsgeglühten und anschließend ausscheidungsgehärteten Zustand weist das Material die höchste Lebensdauer, insbesondere bei einer niedrigen Dehnungsamplitude (Δε/2 = ±0,35 %), bei 650 °C auf.}}, author = {{Aydinöz, Mehmet Esat}}, isbn = {{ 978-3-8440-6475-9}}, keywords = {{Additive Fertigung, Laserschmelzverfahren, Nickelbasis-Superlegierung, Inconel 718, Mikrostruktur, mechanische Eigenschaften, Heißisostatisches Pressen, Beschichtung}}, pages = {{118}}, title = {{{Mikrostrukturelle und mechanische Eigenschaften der im Laserschmelzverfahren verarbeiteten Inconel 718 Nickelbasis-Superlegierung}}}, volume = {{10}}, year = {{2019}}, } @inproceedings{3287, abstract = {{For optimal placement and orchestration of network services, it is crucial that their structure and semantics are specified clearly and comprehensively and are available to an orchestrator. Existing specification approaches are either ambiguous or miss important aspects regarding the behavior of virtual network functions (VNFs) forming a service. We propose to formally and unambiguously specify the behavior of these functions and services using Queuing Petri Nets (QPNs). QPNs are an established method that allows to express queuing, synchronization, stochastically distributed processing delays, and changing traffic volume and characteristics at each VNF. With QPNs, multiple VNFs can be connected to complete network services in any structure, even specifying bidirectional network services containing loops. We discuss how management and orchestration systems can benefit from our clear and comprehensive specification approach, leading to better placement of VNFs and improved Quality of Service. Another benefit of formally specifying network services with QPNs are diverse analysis options, which allow valuable insights such as the distribution of end-to-end delay. We propose a tool-based workflow that supports the specification of network services and the automatic generation of corresponding simulation code to enable an in-depth analysis of their behavior and performance.}}, author = {{Schneider, Stefan Balthasar and Sharma, Arnab and Karl, Holger and Wehrheim, Heike}}, booktitle = {{2019 IFIP/IEEE International Symposium on Integrated Network Management (IM)}}, location = {{Washington, DC, USA}}, pages = {{116----124}}, publisher = {{IFIP}}, title = {{{Specifying and Analyzing Virtual Network Services Using Queuing Petri Nets}}}, year = {{2019}}, } @article{3585, abstract = {{Existing approaches and tools for the generation of approximate circuits often lack generality and are restricted to certain circuit types, approximation techniques, and quality assurance methods. Moreover, only few tools are publicly available. This hinders the development and evaluation of new techniques for approximating circuits and their comparison to previous approaches. In this paper, we first analyze and classify related approaches and then present CIRCA, our flexible framework for search-based approximate circuit generation. CIRCA is developed with a focus on modularity and extensibility. We present the architecture of CIRCA with its clear separation into stages and functional blocks, report on the current prototype, and show initial experiments.}}, author = {{Witschen, Linus Matthias and Wiersema, Tobias and Ghasemzadeh Mohammadi, Hassan and Awais, Muhammad and Platzner, Marco}}, issn = {{0026-2714}}, journal = {{Microelectronics Reliability}}, keywords = {{Approximate Computing, Framework, Pareto Front, Accuracy}}, pages = {{277--290}}, publisher = {{Elsevier}}, title = {{{CIRCA: Towards a Modular and Extensible Framework for Approximate Circuit Generation}}}, doi = {{10.1016/j.microrel.2019.04.003}}, volume = {{99}}, year = {{2019}}, } @inbook{28790, author = {{Vennemann, Mario and Eickelmann, Birgit and Bos, Wilfried and Wendt, Heike}}, booktitle = {{Grundschulpädagogik zwischen Wissenschaft und Transfer (Jahrbuch Grundschulforschung)}}, editor = {{Donie, Christian and Foerster, Frank and Obermayr, Marlene and Deckwerth, Anne and Kammermeyer, Gisela and Lenske, Gerlinde and Leuchter, Miriam and Wildemann, Anja}}, pages = {{427--432}}, publisher = {{VS Verlag}}, title = {{{Die Relevanz schulischer Kompositionsmerkmale für die Entwicklung mathematischer Kompetenzen am Ende der Grundschulzeit}}}, volume = {{23}}, year = {{2019}}, } @inbook{28791, author = {{Lorenz, Ramona and Endberg, Manuela and Eickelmann, Birgit}}, booktitle = {{Lehrer. Bildung. Gestalten. Beiträge zur empirischen Forschung in der Lehrerbildung}}, editor = {{Ehmke, Timo and Kuhl, Poldi and Pietsch, Marcus}}, pages = {{142--152}}, publisher = {{Beltz-Verlag}}, title = {{{Medienbezogene Kompetenzen von Lehrpersonen – Empirische Befunde und Perspektiven für die Lehrerausbildung}}}, year = {{2019}}, } @inbook{28792, author = {{Drossel, Kerstin and Eickelmann, Birgit}}, booktitle = {{Lehrer. Bildung. Gestalten. Beiträge zur empirischen Forschung in der Lehrerbildung}}, editor = {{Ehmke, Timo and Kuhl, Poldi and Pietsch, Marcus}}, pages = {{97--109}}, publisher = {{Beltz-Verlag}}, title = {{{Die Implementation digitaler Medien gestalten: zur Bedeutung der Einstellungen von Fremdsprachenlehrkräften}}}, year = {{2019}}, } @inbook{28795, author = {{Vennemann, Mario and Schwippert, Knut and Eickelmann, Birgit and Massek, Corinna}}, booktitle = {{ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking}}, editor = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, pages = {{335--365}}, publisher = {{Waxmann}}, title = {{{Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern mit und ohne Migrationshintergrund im zweiten internationalen Vergleich}}}, year = {{2019}}, } @inbook{28797, author = {{Senkbeil, Martin and Drossel, Kerstin and Eickelmann, Birgit and Vennemann, Mario}}, booktitle = {{ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking}}, editor = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, pages = {{301--333}}, publisher = {{Waxmann}}, title = {{{Soziale Herkunft und computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich}}}, year = {{2019}}, } @inbook{28799, author = {{Gerick, Julia and Massek, Corinna and Eickelmann, Birgit and Labusch, Amelie}}, booktitle = {{ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking}}, editor = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, pages = {{271--300}}, publisher = {{Waxmann}}, title = {{{Computer- und informationsbezogene Kompetenzen von Mädchen und Jungen im zweiten internationalen Vergleich}}}, year = {{2019}}, } @inbook{28814, author = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, booktitle = {{ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking}}, editor = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, pages = {{33--77}}, publisher = {{Waxmann}}, title = {{{Anlage, Forschungsdesign und Durchführung der Studie ICILS 2018}}}, year = {{2019}}, } @book{28819, editor = {{Eickelmann, Birgit and Bos, Wilfried and Gerick, Julia and Goldhammer, Frank and Schaumburg, Heike and Schwippert, Knut and Senkbeil, Martin and Vahrenhold, Jan}}, publisher = {{Waxmann}}, title = {{{ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking}}}, year = {{2019}}, } @misc{28826, author = {{Gerick, Julia and Eickelmann, Birgit and Steglich, Emilie}}, publisher = {{Universität Hamburg/Universität Paderborn}}, title = {{{Kurzzusammenfassung der Ergebnisse der prozessbegleitenden wissenschaftlichen Evaluation der Einführung von LOGINEO NRW an Pilotschulen}}}, year = {{2019}}, } @misc{28828, author = {{Gerick, Julia and Eickelmann, Birgit and Steglich, Emilie}}, publisher = {{Universität Hamburg/Universität Paderborn}}, title = {{{Abschlussbericht zur prozessbegleitenden Evaluation der Einführung von LOGINEO NRW an Pilotschulen}}}, year = {{2019}}, } @inbook{28830, author = {{Eickelmann, Birgit}}, booktitle = {{Steuerung und Qualitätsentwicklung im Fortbildungssystem. Probleme und Befunde – Standardbildung und Lösungsansätze}}, editor = {{Priebe, Botho and Böttcher, Wolfgang and Heinemann, Ulrich and Kubina, Christian}}, pages = {{208--228}}, publisher = {{Klett/Kallmeyer}}, title = {{{Lehrerfortbildung im Kontext der digitalen Transformation: Herausforderungen, Befunde und Perspektiven für eine zukunftsfähige Gestaltung des Bildungssystems}}}, year = {{2019}}, } @article{2916, author = {{Brauer, Sascha}}, issn = {{0304-3975}}, journal = {{Theoretical Computer Science}}, pages = {{88--106}}, publisher = {{Elsevier}}, title = {{{Complexity of single-swap heuristics for metric facility location and related problems}}}, doi = {{10.1016/j.tcs.2018.04.048}}, volume = {{754}}, year = {{2019}}, } @article{27003, author = {{Perrar, Ines and Schmitting, Sarah and Della Corte, Karen W. and Buyken, Anette and Alexy, Ute}}, issn = {{1436-6207}}, journal = {{European Journal of Nutrition}}, pages = {{1043--1054}}, title = {{{Age and time trends in sugar intake among children and adolescents: results from the DONALD study}}}, doi = {{10.1007/s00394-019-01965-y}}, year = {{2019}}, } @article{27004, author = {{Wong, Tommy H. T. and Buyken, Anette and Brand-Miller, Jennie C. and Louie, Jimmy Chun Yu}}, issn = {{1436-6207}}, journal = {{European Journal of Nutrition}}, pages = {{2357--2367}}, title = {{{Is there a soft drink vs. alcohol seesaw? A cross-sectional analysis of dietary data in the Australian Health Survey 2011–12}}}, doi = {{10.1007/s00394-019-02084-4}}, year = {{2019}}, } @article{27005, abstract = {{ABSTRACT Background There is controversy on the relevance of dietary sugar intake for cardiometabolic health. Objective The aim of this network meta-analysis (NMA) was to assess how isocaloric substitutions of dietary sugar with other carbohydrates affect cardiometabolic risk factors, comparing different intervention studies. Methods We included randomized controlled trials (RCTs) investigating the isocaloric effect of substituting dietary sugars (fructose, glucose, sucrose) with other sugars or starch on cardiometabolic risk markers, including LDL cholesterol, triacylglycerol (TG), fasting glucose (FG), glycated hemoglobin (HbA1c), insulin resistance (HOMA-IR), uric acid, C-reactive protein (CRP), alanine transaminase (ALT), aspartate transaminase (AST), and liver fat content. To identify the most beneficial intervention for each outcome, random-effects NMA was conducted by calculating pooled mean differences (MDs) with 95% CIs, and by ranking the surface under the cumulative ranking curves (SUCRAs). The certainty of evidence was evaluated using the Confidence In Network Meta-Analysis tool. Results Thirty-eight RCTs, including 1383 participants, were identified. A reduction in LDL-cholesterol concentrations was shown for the exchange of sucrose with starch (MD: −0.23 mmol/L; 95% CI: −0.38, −0.07 mmol/L) or fructose with starch (MD: −0.22 mmol/L; 95% CI: −0.39, −0.05 mmol/L; SUCRAstarch: 98%). FG concentrations were also lower for the exchange of sucrose with starch (MD: −0.14 mmol/L; 95% CI: −0.29, 0.01 mmol/L; SUCRAstarch: 91%). Replacing fructose with an equivalent energy amount of glucose reduced HOMA-IR (MD: −0.36; 95% CI: −0.71, −0.02; SUCRAglucose: 74%) and uric acid (MD: −23.77 µmol/L; 95% CI: −44.21, −3.32 µmol/L; SUCRAglucose: 93%). The certainty of evidence was rated very low to moderate. No significant effects were observed for TG, HbA1c, CRP, ALT, and AST. Conclusions Our findings indicate that substitution of sucrose and fructose with starch yielded lower LDL cholesterol. Insulin resistance and uric acid concentrations were beneficially affected by replacement of fructose with glucose. Our findings are limited by the very low to moderate certainty of evidence. This review was registered at www.crd.york.ac.uk/prospero as CRD42018080297. }}, author = {{Schwingshackl, Lukas and Neuenschwander, Manuela and Hoffmann, Georg and Buyken, Anette and Schlesinger, Sabrina}}, issn = {{0002-9165}}, journal = {{The American Journal of Clinical Nutrition}}, title = {{{Dietary sugars and cardiometabolic risk factors: a network meta-analysis on isocaloric substitution interventions}}}, doi = {{10.1093/ajcn/nqz273}}, year = {{2019}}, } @article{27006, abstract = {{Trend analyses suggest that free sugar (FS) intake—while still exceeding 10%E—has decreased among German children and adolescents since 2005, yet that intakes may shift from sugars naturally occurring in foods to added sugars as children age. Thus, we analysed time and age trends in FS intake (%E) from food groups among 3–18 year-olds (1985–2016) using 10,761 3-day dietary records from 1312 DONALD participants (660 boys, 652 girls) by use of polynomial mixed-effects regression models. Among girls, FS from sugar & sweets decreased from 1985 to 2016 (linear trend p < 0.0001), but not among boys (p > 0.05). In the total sample, FS intake from juices increased until 2000 and decreased since 2005 (linear, quadratic trend p < 0.0001). FS from sugar sweetened beverages (SSB) decreased non-linearly from 1985 to 2016 (girls: linear, quadratic, cubic trend p < 0.0001; boys: linear, quadratic, cubic trend p < 0.02). Younger children consumed more FS from juices than older ones, who had a higher FS intake from SSB. FS intake from sugar & sweets increased until early adolescence and decreased afterwards. Since sugar & sweets represent the main source of FS intake and the source with the least pronounced decline in intake, public health measures should focus on these products.}}, author = {{Perrar, Ines and Schadow, Alena M. and Schmitting, Sarah and Buyken, Anette and Alexy, Ute}}, issn = {{2072-6643}}, journal = {{Nutrients}}, title = {{{Time and Age Trends in Free Sugar Intake from Food Groups among Children and Adolescents between 1985 and 2016}}}, doi = {{10.3390/nu12010020}}, year = {{2019}}, } @article{27023, abstract = {{Abstract Background Blood immunoreactive biomarkers, such as C-reactive protein (CRP), and metabolic abnormalities have been associated with schizophrenia. Studies comprehensively and bidirectionally probing possible causal links between such blood constituents and liability to schizophrenia are lacking. Methods To disentangle putative causal links between CRP blood levels and schizophrenia in both directions, we conducted multiple univariable Mendelian-randomization (MR) analyses, ranging from fixed-effect to inverse variance-weighted (IVW), weighted-median, MR Egger and generalized summary-data-based Mendelian-randomization (GSMR) models. To prioritize metabolic risk factors for schizophrenia, a novel multivariable approach was applied: multivariable Mendelian-randomization–Bayesian model averaging (MR-BMA). Results All forward univariable MR analyses consistently showed that CRP has a protective effect on schizophrenia, whereas reverse MR analyses consistently suggested absent causal effects of schizophrenia liability on CRP blood levels. Using MR-BMA, as the top protective factors for schizophrenia we prioritized leucine and as the prime risk-factor triglycerides in medium very-low-density lipoprotein (VLDL). The five best-performing MR-BMA models provided one additional risk factor: triglycerides in large VLDL; and two additional protective factors: citrate and lactate. Conclusions Our results add to a growing body of literature hinting at metabolic changes—in particular of triglycerides—independently of medication status in schizophrenia. We also highlight the absent effects of genetic liability to schizophrenia on CRP levels. }}, author = {{Lin, Bochao D and Alkema, Anne and Peters, Triinu and Zinkstok, Janneke and Libuda, Lars and Hebebrand, Johannes and Antel, Jochen and Hinney, Anke and Cahn, Wiepke and Adan, Roger and Luykx, Jurjen J}}, issn = {{0300-5771}}, journal = {{International Journal of Epidemiology}}, pages = {{1505--1514}}, title = {{{Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study}}}, doi = {{10.1093/ije/dyz176}}, year = {{2019}}, } @article{27024, author = {{Kalhoff, Hermann and Mesch, Christina M. and Stimming, Madlen and Israel, Andreas and Spitzer, Christoph and Beganovic, Latifa and Perez, Rocio Estella and Koletzko, Berthold and Warschburger, Petra and Kersting, Mathilde and Libuda, Lars}}, issn = {{0954-3007}}, journal = {{European Journal of Clinical Nutrition}}, pages = {{682--690}}, title = {{{Effects of LC-PUFA supply via complementary food on infant development—a food based intervention (RCT) embedded in a total diet concept}}}, doi = {{10.1038/s41430-019-0491-0}}, year = {{2019}}, } @inproceedings{27101, author = {{Drewel, Marvin and Gausemeier, Jürgen and Vaßholz, Mareen and Homburg, Nils}}, booktitle = {{Symposium für Vorausschau und Technologieplanung, Band 15}}, editor = {{Gausemeier, Jürgen and Bauer, Wilhelm and Dumitrescu, Roman}}, publisher = {{Heinz Nixdorf Institut}}, title = {{{Einstieg in die Plattformökonomie}}}, year = {{2019}}, } @article{27102, abstract = {{Mithilfe von Industrie 4.0-Reifegradmodellen können Unternehmen ihren Leistungsstand im Kontext Industrie 4.0 systematisch erfassen. Mit der Ermittlung des Status Quos ist in aller Regel die Frage verbunden „Wo wollen wir zukünftig hin?“. Vor dem Hintergrund, dass Unternehmen aus unterschiedlichen Gründen nicht immer das grundsätzlich Mögliche einführen können, ist die Beantwortung dieser Frage nicht trivial. Ist sich ein Unternehmen über seine I4.0-Zielposition vermeintlich im Klaren, führen äußere Einflüsse häufig dazu, dass die Zielerreichung erschwert wird, was oftmals eine Anpassung der Zielposition zur Folge hat. Es gilt also, diese Umstände bereits in der Planung zu berücksichtigen. Der vorliegende Beitrag zeigt auf, wie Umfeldentwicklungen bei der Ermittlung einer Erfolg versprechenden I4.0-Zielposition von Unternehmen einbezogen werden können.}}, author = {{Pierenkemper, Christoph and Reinhold, Jannik and Dumitrescu, Roman and Gausemeier, Jürgen}}, journal = {{Industrie 4.0 Management (5)}}, pages = {{30--34}}, title = {{{Erfolg versprechende Industrie 4.0-Zielposition - Ermittlung unter Berücksichtigung zukünftiger Umfeldentwicklungen}}}, year = {{2019}}, } @inproceedings{27103, abstract = {{One of the notable drivers of the fourth industrial revolution is the collection of vast amounts of data along the entire lifecycle of a product. The analysis of product lifecycle data in conjunction with product hypotheses leads to promising potentials in strategic product planning. In this thesis paper, we postulate the need for data-driven product generation and retrofit planning as an interdisciplinary field of research. We define and analyze the key concepts and derive requirements in a structured way. Based on an exhaustive research of existing approaches, we structure open research questions and propose a roadmap in order to shape future research efforts. }}, author = {{Massmann, Melina and Meyer, Maurice and Dumitrescu, Roman and von Enzberg, Sebastian and Frank, Maximilian and Koldewey, Christian and Kühn, Arno and Reinhold, Jannik}}, booktitle = {{Proceedings of the CIRP DESIGN}}, publisher = {{Scientific Technical Committee Design of the International Academy for Production Engineering (CIRP)}}, title = {{{Significance and Challenges of Data-driven Product Generation and Retrofit Planning}}}, year = {{2019}}, } @inproceedings{27104, abstract = {{Today's manufacturing industry is confronted with fundamental changes in value creation. The tension between the two megatrends of digitization and servitization leads to new hybrid market offerings, so-called smart services. Corresponding value networks fundamentally differ from traditional ones. Developing smart services requires new competences in young disciplines, while their provision requires new internal and external organizational structures or processes. To strengthen their competitive position, manufacturing companies need to adapt their value networks. However, the highly complex transformation of value crea-tion especially challenges small and medium-sized companies due to limited competences and resources. They must consider opening their boundaries and collaborating with partners. In this paper, we introduce a basic framework for planning smart services and present a methodology for competence-based plan-ning of value networks for smart services in three phases: Smart service analysis, competence analysis and value creation planning. The methodology is explained by an example from tooling machine industry.}}, author = {{Reinhold, Jannik and Frank, Maximilian and Koldewey, Christian and Dumitrescu, Roman and Gausemeier, Jürgen}}, booktitle = {{Proceedings of the ISPIM Connects}}, publisher = {{International Society for Professional Innovation Management (ISPIM)}}, title = {{{Competence-based Planning of Value Networks for Smart Services}}}, year = {{2019}}, } @inproceedings{27105, author = {{Wortmann, Fabio and Joppen, Robert and Drewel, Marvin and Kühn, Arno and Dumitrescu, Roman}}, booktitle = {{IAMOT 2019 – Proceedings of the 28th International Association for Management of Technology Conference}}, editor = {{Jain, K. and Sangle, S. and Gupta, R. and Persis, J. and Mukundan, R.}}, publisher = {{International Association for Management of Technology (IAMOT)}}, title = {{{Developing and Evaluating Concepts for a Digital Platform}}}, year = {{2019}}, }