TY - CHAP
AU - Lorenz, Ramona
AU - Endberg, Manuela
AU - Eickelmann, Birgit
ED - Ehmke, Timo
ED - Kuhl, Poldi
ED - Pietsch, Marcus
ID - 28791
T2 - Lehrer. Bildung. Gestalten. Beiträge zur empirischen Forschung in der Lehrerbildung
TI - Medienbezogene Kompetenzen von Lehrpersonen – Empirische Befunde und Perspektiven für die Lehrerausbildung
ER -
TY - CHAP
AU - Drossel, Kerstin
AU - Eickelmann, Birgit
ED - Ehmke, Timo
ED - Kuhl, Poldi
ED - Pietsch, Marcus
ID - 28792
T2 - Lehrer. Bildung. Gestalten. Beiträge zur empirischen Forschung in der Lehrerbildung
TI - Die Implementation digitaler Medien gestalten: zur Bedeutung der Einstellungen von Fremdsprachenlehrkräften
ER -
TY - CHAP
AU - Vennemann, Mario
AU - Schwippert, Knut
AU - Eickelmann, Birgit
AU - Massek, Corinna
ED - Eickelmann, Birgit
ED - Bos, Wilfried
ED - Gerick, Julia
ED - Goldhammer, Frank
ED - Schaumburg, Heike
ED - Schwippert, Knut
ED - Senkbeil, Martin
ED - Vahrenhold, Jan
ID - 28795
T2 - ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking
TI - Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern mit und ohne Migrationshintergrund im zweiten internationalen Vergleich
ER -
TY - CHAP
AU - Senkbeil, Martin
AU - Drossel, Kerstin
AU - Eickelmann, Birgit
AU - Vennemann, Mario
ED - Eickelmann, Birgit
ED - Bos, Wilfried
ED - Gerick, Julia
ED - Goldhammer, Frank
ED - Schaumburg, Heike
ED - Schwippert, Knut
ED - Senkbeil, Martin
ED - Vahrenhold, Jan
ID - 28797
T2 - ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking
TI - Soziale Herkunft und computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich
ER -
TY - CHAP
AU - Gerick, Julia
AU - Massek, Corinna
AU - Eickelmann, Birgit
AU - Labusch, Amelie
ED - Eickelmann, Birgit
ED - Bos, Wilfried
ED - Gerick, Julia
ED - Goldhammer, Frank
ED - Schaumburg, Heike
ED - Schwippert, Knut
ED - Senkbeil, Martin
ED - Vahrenhold, Jan
ID - 28799
T2 - ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking
TI - Computer- und informationsbezogene Kompetenzen von Mädchen und Jungen im zweiten internationalen Vergleich
ER -
TY - CHAP
AU - Eickelmann, Birgit
AU - Bos, Wilfried
AU - Gerick, Julia
AU - Goldhammer, Frank
AU - Schaumburg, Heike
AU - Schwippert, Knut
AU - Senkbeil, Martin
AU - Vahrenhold, Jan
ED - Eickelmann, Birgit
ED - Bos, Wilfried
ED - Gerick, Julia
ED - Goldhammer, Frank
ED - Schaumburg, Heike
ED - Schwippert, Knut
ED - Senkbeil, Martin
ED - Vahrenhold, Jan
ID - 28814
T2 - ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking
TI - Anlage, Forschungsdesign und Durchführung der Studie ICILS 2018
ER -
TY - BOOK
ED - Eickelmann, Birgit
ED - Bos, Wilfried
ED - Gerick, Julia
ED - Goldhammer, Frank
ED - Schaumburg, Heike
ED - Schwippert, Knut
ED - Senkbeil, Martin
ED - Vahrenhold, Jan
ID - 28819
TI - ICILS 2018 #Deutschland – Computer- und informationsbezogene Kompetenzen von Schülerinnen und Schülern im zweiten internationalen Vergleich und Kompetenzen im Bereich Computational Thinking
ER -
TY - DATA
AU - Gerick, Julia
AU - Eickelmann, Birgit
AU - Steglich, Emilie
ID - 28826
TI - Kurzzusammenfassung der Ergebnisse der prozessbegleitenden wissenschaftlichen Evaluation der Einführung von LOGINEO NRW an Pilotschulen
ER -
TY - DATA
AU - Gerick, Julia
AU - Eickelmann, Birgit
AU - Steglich, Emilie
ID - 28828
TI - Abschlussbericht zur prozessbegleitenden Evaluation der Einführung von LOGINEO NRW an Pilotschulen
ER -
TY - CHAP
AU - Eickelmann, Birgit
ED - Priebe, Botho
ED - Böttcher, Wolfgang
ED - Heinemann, Ulrich
ED - Kubina, Christian
ID - 28830
T2 - Steuerung und Qualitätsentwicklung im Fortbildungssystem. Probleme und Befunde – Standardbildung und Lösungsansätze
TI - Lehrerfortbildung im Kontext der digitalen Transformation: Herausforderungen, Befunde und Perspektiven für eine zukunftsfähige Gestaltung des Bildungssystems
ER -
TY - JOUR
AU - Brauer, Sascha
ID - 2916
JF - Theoretical Computer Science
SN - 0304-3975
TI - Complexity of single-swap heuristics for metric facility location and related problems
VL - 754
ER -
TY - JOUR
AU - Perrar, Ines
AU - Schmitting, Sarah
AU - Della Corte, Karen W.
AU - Buyken, Anette
AU - Alexy, Ute
ID - 27003
JF - European Journal of Nutrition
SN - 1436-6207
TI - Age and time trends in sugar intake among children and adolescents: results from the DONALD study
ER -
TY - JOUR
AU - Wong, Tommy H. T.
AU - Buyken, Anette
AU - Brand-Miller, Jennie C.
AU - Louie, Jimmy Chun Yu
ID - 27004
JF - European Journal of Nutrition
SN - 1436-6207
TI - Is there a soft drink vs. alcohol seesaw? A cross-sectional analysis of dietary data in the Australian Health Survey 2011–12
ER -
TY - JOUR
AB - ABSTRACT
Background
There is controversy on the relevance of dietary sugar intake for cardiometabolic health.
Objective
The aim of this network meta-analysis (NMA) was to assess how isocaloric substitutions of dietary sugar with other carbohydrates affect cardiometabolic risk factors, comparing different intervention studies.
Methods
We included randomized controlled trials (RCTs) investigating the isocaloric effect of substituting dietary sugars (fructose, glucose, sucrose) with other sugars or starch on cardiometabolic risk markers, including LDL cholesterol, triacylglycerol (TG), fasting glucose (FG), glycated hemoglobin (HbA1c), insulin resistance (HOMA-IR), uric acid, C-reactive protein (CRP), alanine transaminase (ALT), aspartate transaminase (AST), and liver fat content. To identify the most beneficial intervention for each outcome, random-effects NMA was conducted by calculating pooled mean differences (MDs) with 95% CIs, and by ranking the surface under the cumulative ranking curves (SUCRAs). The certainty of evidence was evaluated using the Confidence In Network Meta-Analysis tool.
Results
Thirty-eight RCTs, including 1383 participants, were identified. A reduction in LDL-cholesterol concentrations was shown for the exchange of sucrose with starch (MD: −0.23 mmol/L; 95% CI: −0.38, −0.07 mmol/L) or fructose with starch (MD: −0.22 mmol/L; 95% CI: −0.39, −0.05 mmol/L; SUCRAstarch: 98%). FG concentrations were also lower for the exchange of sucrose with starch (MD: −0.14 mmol/L; 95% CI: −0.29, 0.01 mmol/L; SUCRAstarch: 91%). Replacing fructose with an equivalent energy amount of glucose reduced HOMA-IR (MD: −0.36; 95% CI: −0.71, −0.02; SUCRAglucose: 74%) and uric acid (MD: −23.77 µmol/L; 95% CI: −44.21, −3.32 µmol/L; SUCRAglucose: 93%). The certainty of evidence was rated very low to moderate. No significant effects were observed for TG, HbA1c, CRP, ALT, and AST.
Conclusions
Our findings indicate that substitution of sucrose and fructose with starch yielded lower LDL cholesterol. Insulin resistance and uric acid concentrations were beneficially affected by replacement of fructose with glucose. Our findings are limited by the very low to moderate certainty of evidence. This review was registered at www.crd.york.ac.uk/prospero as CRD42018080297.
AU - Schwingshackl, Lukas
AU - Neuenschwander, Manuela
AU - Hoffmann, Georg
AU - Buyken, Anette
AU - Schlesinger, Sabrina
ID - 27005
JF - The American Journal of Clinical Nutrition
SN - 0002-9165
TI - Dietary sugars and cardiometabolic risk factors: a network meta-analysis on isocaloric substitution interventions
ER -
TY - JOUR
AB - Trend analyses suggest that free sugar (FS) intake—while still exceeding 10%E—has decreased among German children and adolescents since 2005, yet that intakes may shift from sugars naturally occurring in foods to added sugars as children age. Thus, we analysed time and age trends in FS intake (%E) from food groups among 3–18 year-olds (1985–2016) using 10,761 3-day dietary records from 1312 DONALD participants (660 boys, 652 girls) by use of polynomial mixed-effects regression models. Among girls, FS from sugar & sweets decreased from 1985 to 2016 (linear trend p < 0.0001), but not among boys (p > 0.05). In the total sample, FS intake from juices increased until 2000 and decreased since 2005 (linear, quadratic trend p < 0.0001). FS from sugar sweetened beverages (SSB) decreased non-linearly from 1985 to 2016 (girls: linear, quadratic, cubic trend p < 0.0001; boys: linear, quadratic, cubic trend p < 0.02). Younger children consumed more FS from juices than older ones, who had a higher FS intake from SSB. FS intake from sugar & sweets increased until early adolescence and decreased afterwards. Since sugar & sweets represent the main source of FS intake and the source with the least pronounced decline in intake, public health measures should focus on these products.
AU - Perrar, Ines
AU - Schadow, Alena M.
AU - Schmitting, Sarah
AU - Buyken, Anette
AU - Alexy, Ute
ID - 27006
JF - Nutrients
SN - 2072-6643
TI - Time and Age Trends in Free Sugar Intake from Food Groups among Children and Adolescents between 1985 and 2016
ER -
TY - JOUR
AB - Abstract
Background
Blood immunoreactive biomarkers, such as C-reactive protein (CRP), and metabolic abnormalities have been associated with schizophrenia. Studies comprehensively and bidirectionally probing possible causal links between such blood constituents and liability to schizophrenia are lacking.
Methods
To disentangle putative causal links between CRP blood levels and schizophrenia in both directions, we conducted multiple univariable Mendelian-randomization (MR) analyses, ranging from fixed-effect to inverse variance-weighted (IVW), weighted-median, MR Egger and generalized summary-data-based Mendelian-randomization (GSMR) models. To prioritize metabolic risk factors for schizophrenia, a novel multivariable approach was applied: multivariable Mendelian-randomization–Bayesian model averaging (MR-BMA).
Results
All forward univariable MR analyses consistently showed that CRP has a protective effect on schizophrenia, whereas reverse MR analyses consistently suggested absent causal effects of schizophrenia liability on CRP blood levels. Using MR-BMA, as the top protective factors for schizophrenia we prioritized leucine and as the prime risk-factor triglycerides in medium very-low-density lipoprotein (VLDL). The five best-performing MR-BMA models provided one additional risk factor: triglycerides in large VLDL; and two additional protective factors: citrate and lactate.
Conclusions
Our results add to a growing body of literature hinting at metabolic changes—in particular of triglycerides—independently of medication status in schizophrenia. We also highlight the absent effects of genetic liability to schizophrenia on CRP levels.
AU - Lin, Bochao D
AU - Alkema, Anne
AU - Peters, Triinu
AU - Zinkstok, Janneke
AU - Libuda, Lars
AU - Hebebrand, Johannes
AU - Antel, Jochen
AU - Hinney, Anke
AU - Cahn, Wiepke
AU - Adan, Roger
AU - Luykx, Jurjen J
ID - 27023
JF - International Journal of Epidemiology
SN - 0300-5771
TI - Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study
ER -
TY - JOUR
AU - Kalhoff, Hermann
AU - Mesch, Christina M.
AU - Stimming, Madlen
AU - Israel, Andreas
AU - Spitzer, Christoph
AU - Beganovic, Latifa
AU - Perez, Rocio Estella
AU - Koletzko, Berthold
AU - Warschburger, Petra
AU - Kersting, Mathilde
AU - Libuda, Lars
ID - 27024
JF - European Journal of Clinical Nutrition
SN - 0954-3007
TI - Effects of LC-PUFA supply via complementary food on infant development—a food based intervention (RCT) embedded in a total diet concept
ER -
TY - CONF
AU - Drewel, Marvin
AU - Gausemeier, Jürgen
AU - Vaßholz, Mareen
AU - Homburg, Nils
ED - Gausemeier, Jürgen
ED - Bauer, Wilhelm
ED - Dumitrescu, Roman
ID - 27101
T2 - Symposium für Vorausschau und Technologieplanung, Band 15
TI - Einstieg in die Plattformökonomie
ER -
TY - JOUR
AB - Mithilfe von Industrie 4.0-Reifegradmodellen können Unternehmen ihren Leistungsstand im Kontext Industrie 4.0 systematisch erfassen. Mit der Ermittlung des Status Quos ist in aller Regel die Frage verbunden „Wo wollen wir zukünftig hin?“. Vor dem Hintergrund, dass Unternehmen aus unterschiedlichen Gründen nicht immer das grundsätzlich Mögliche einführen können, ist die Beantwortung dieser Frage nicht trivial. Ist sich ein Unternehmen über seine I4.0-Zielposition vermeintlich im Klaren, führen äußere Einflüsse häufig dazu, dass die Zielerreichung erschwert wird, was oftmals eine Anpassung der Zielposition zur Folge hat. Es gilt also, diese Umstände bereits in der Planung zu berücksichtigen. Der vorliegende Beitrag zeigt auf, wie Umfeldentwicklungen bei der Ermittlung einer Erfolg versprechenden I4.0-Zielposition von Unternehmen einbezogen werden können.
AU - Pierenkemper, Christoph
AU - Reinhold, Jannik
AU - Dumitrescu, Roman
AU - Gausemeier, Jürgen
ID - 27102
JF - Industrie 4.0 Management (5)
TI - Erfolg versprechende Industrie 4.0-Zielposition - Ermittlung unter Berücksichtigung zukünftiger Umfeldentwicklungen
ER -
TY - CONF
AB - One of the notable drivers of the fourth industrial revolution is the collection of vast amounts of data along the entire lifecycle of a product. The analysis of product lifecycle data in conjunction with product hypotheses leads to promising potentials in strategic product planning. In this thesis paper, we postulate the need for data-driven product generation and retrofit planning as an interdisciplinary field of research. We define and analyze the key concepts and derive requirements in a structured way. Based on an exhaustive research of existing approaches, we structure open research questions and propose a roadmap in order to shape future research efforts.
AU - Massmann, Melina
AU - Meyer, Maurice
AU - Dumitrescu, Roman
AU - von Enzberg, Sebastian
AU - Frank, Maximilian
AU - Koldewey, Christian
AU - Kühn, Arno
AU - Reinhold, Jannik
ID - 27103
T2 - Proceedings of the CIRP DESIGN
TI - Significance and Challenges of Data-driven Product Generation and Retrofit Planning
ER -