---
_id: '22646'
abstract:
- lang: eng
text: "Abstract\r\nThe surface-assisted hierarchical
self-assembly of DNA origami lattices represents a versatile and straightforward
method for the organization of functional nanoscale objects such as proteins and
nanoparticles. Here, we demonstrate that controlling the binding and exchange
of different monovalent and divalent cation species at the DNA-mica interface
enables the self-assembly of highly ordered DNA origami lattices on mica surfaces.
The development of lattice quality and order is quantified by a detailed topological
analysis of high-speed atomic force microscopy (HS-AFM) images. We find that lattice
formation and quality strongly depend on the monovalent cation species. Na+
is more effective than Li+ and K+ in
facilitating the assembly of high-quality DNA origami lattices, because it is
replacing the divalent cations at their binding sites in the DNA backbone more
efficiently. With regard to divalent cations, Ca2+ can be
displaced more easily from the backbone phosphates than Mg2+
and is thus superior in guiding lattice assembly. By independently adjusting incubation
time, DNA origami concentration, and cation species, we thus obtain a highly ordered
DNA origami lattice with an unprecedented normalized correlation length of 8.2.
Beyond the correlation length, we use computer vision algorithms to compute the
time course of different topological observables that, overall, demonstrate that
replacing MgCl2 by CaCl2 enables the
synthesis of DNA origami lattices with drastically increased lattice order."
author:
- first_name: Yang
full_name: Xin, Yang
last_name: Xin
- first_name: Salvador
full_name: Martinez Rivadeneira, Salvador
last_name: Martinez Rivadeneira
- first_name: Guido
full_name: Grundmeier, Guido
id: '194'
last_name: Grundmeier
- first_name: Mario
full_name: Castro, Mario
last_name: Castro
- first_name: Adrian
full_name: Keller, Adrian
id: '48864'
last_name: Keller
orcid: 0000-0001-7139-3110
citation:
ama: Xin Y, Martinez Rivadeneira S, Grundmeier G, Castro M, Keller A. Self-assembly
of highly ordered DNA origami lattices at solid-liquid interfaces by controlling
cation binding and exchange. Nano Research. 2020;13:3142-3150. doi:10.1007/s12274-020-2985-4
apa: Xin, Y., Martinez Rivadeneira, S., Grundmeier, G., Castro, M., & Keller,
A. (2020). Self-assembly of highly ordered DNA origami lattices at solid-liquid
interfaces by controlling cation binding and exchange. Nano Research, 13,
3142–3150. https://doi.org/10.1007/s12274-020-2985-4
bibtex: '@article{Xin_Martinez Rivadeneira_Grundmeier_Castro_Keller_2020, title={Self-assembly
of highly ordered DNA origami lattices at solid-liquid interfaces by controlling
cation binding and exchange}, volume={13}, DOI={10.1007/s12274-020-2985-4},
journal={Nano Research}, author={Xin, Yang and Martinez Rivadeneira, Salvador
and Grundmeier, Guido and Castro, Mario and Keller, Adrian}, year={2020}, pages={3142–3150}
}'
chicago: 'Xin, Yang, Salvador Martinez Rivadeneira, Guido Grundmeier, Mario Castro,
and Adrian Keller. “Self-Assembly of Highly Ordered DNA Origami Lattices at Solid-Liquid
Interfaces by Controlling Cation Binding and Exchange.” Nano Research 13
(2020): 3142–50. https://doi.org/10.1007/s12274-020-2985-4.'
ieee: Y. Xin, S. Martinez Rivadeneira, G. Grundmeier, M. Castro, and A. Keller,
“Self-assembly of highly ordered DNA origami lattices at solid-liquid interfaces
by controlling cation binding and exchange,” Nano Research, vol. 13, pp.
3142–3150, 2020.
mla: Xin, Yang, et al. “Self-Assembly of Highly Ordered DNA Origami Lattices at
Solid-Liquid Interfaces by Controlling Cation Binding and Exchange.” Nano Research,
vol. 13, 2020, pp. 3142–50, doi:10.1007/s12274-020-2985-4.
short: Y. Xin, S. Martinez Rivadeneira, G. Grundmeier, M. Castro, A. Keller, Nano
Research 13 (2020) 3142–3150.
date_created: 2021-07-08T12:01:03Z
date_updated: 2022-01-06T06:55:37Z
department:
- _id: '302'
doi: 10.1007/s12274-020-2985-4
intvolume: ' 13'
language:
- iso: eng
page: 3142-3150
publication: Nano Research
publication_identifier:
issn:
- 1998-0124
- 1998-0000
publication_status: published
status: public
title: Self-assembly of highly ordered DNA origami lattices at solid-liquid interfaces
by controlling cation binding and exchange
type: journal_article
user_id: '48864'
volume: 13
year: '2020'
...