{"language":[{"iso":"eng"}],"publication_status":"published","doi":"10.1039/c9nr04460d","page":"16270-16276","date_updated":"2022-01-06T06:55:38Z","type":"journal_article","publication":"Nanoscale","status":"public","intvolume":"        11","year":"2019","author":[{"first_name":"Saminathan","last_name":"Ramakrishnan","full_name":"Ramakrishnan, Saminathan"},{"first_name":"Leonard","last_name":"Schärfen","full_name":"Schärfen, Leonard"},{"first_name":"Kristin","last_name":"Hunold","full_name":"Hunold, Kristin"},{"full_name":"Fricke, Sebastian","last_name":"Fricke","first_name":"Sebastian"},{"first_name":"Guido","id":"194","last_name":"Grundmeier","full_name":"Grundmeier, Guido"},{"first_name":"Michael","full_name":"Schlierf, Michael","last_name":"Schlierf"},{"id":"48864","last_name":"Keller","full_name":"Keller, Adrian","orcid":"0000-0001-7139-3110","first_name":"Adrian"},{"first_name":"Georg","last_name":"Krainer","full_name":"Krainer, Georg"}],"abstract":[{"text":"<p>Merging of bridging staples with adjacent oligonucleotide sequences leads to a moderate increase of DNA origami stability, while enzymatic ligation after assembly yields a reinforced nanostructure with superior stability at up to 37 °C and in the presence of 6 M urea.</p>","lang":"eng"}],"title":"Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation","_id":"22653","department":[{"_id":"302"}],"publication_identifier":{"issn":["2040-3364","2040-3372"]},"volume":11,"user_id":"48864","citation":{"chicago":"Ramakrishnan, Saminathan, Leonard Schärfen, Kristin Hunold, Sebastian Fricke, Guido Grundmeier, Michael Schlierf, Adrian Keller, and Georg Krainer. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” <i>Nanoscale</i> 11 (2019): 16270–76. <a href=\"https://doi.org/10.1039/c9nr04460d\">https://doi.org/10.1039/c9nr04460d</a>.","short":"S. Ramakrishnan, L. Schärfen, K. Hunold, S. Fricke, G. Grundmeier, M. Schlierf, A. Keller, G. Krainer, Nanoscale 11 (2019) 16270–16276.","bibtex":"@article{Ramakrishnan_Schärfen_Hunold_Fricke_Grundmeier_Schlierf_Keller_Krainer_2019, title={Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation}, volume={11}, DOI={<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>}, journal={Nanoscale}, author={Ramakrishnan, Saminathan and Schärfen, Leonard and Hunold, Kristin and Fricke, Sebastian and Grundmeier, Guido and Schlierf, Michael and Keller, Adrian and Krainer, Georg}, year={2019}, pages={16270–16276} }","apa":"Ramakrishnan, S., Schärfen, L., Hunold, K., Fricke, S., Grundmeier, G., Schlierf, M., … Krainer, G. (2019). Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. <i>Nanoscale</i>, <i>11</i>, 16270–16276. <a href=\"https://doi.org/10.1039/c9nr04460d\">https://doi.org/10.1039/c9nr04460d</a>","ieee":"S. Ramakrishnan <i>et al.</i>, “Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation,” <i>Nanoscale</i>, vol. 11, pp. 16270–16276, 2019.","mla":"Ramakrishnan, Saminathan, et al. “Enhancing the Stability of DNA Origami Nanostructures: Staple Strand Redesign versus Enzymatic Ligation.” <i>Nanoscale</i>, vol. 11, 2019, pp. 16270–76, doi:<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>.","ama":"Ramakrishnan S, Schärfen L, Hunold K, et al. Enhancing the stability of DNA origami nanostructures: staple strand redesign versus enzymatic ligation. <i>Nanoscale</i>. 2019;11:16270-16276. doi:<a href=\"https://doi.org/10.1039/c9nr04460d\">10.1039/c9nr04460d</a>"},"date_created":"2021-07-08T12:10:44Z"}