---
_id: '25907'
abstract:
- lang: eng
  text: <jats:p>The combined benefits of moisture-stable phosphonic acids and mesoporous
    silica materials (SBA-15 and MCM-41) as large-surface-area solid supports offer
    new opportunities for several applications, such as catalysis or drug delivery.
    We present a comprehensive study of a straightforward synthesis method via direct
    immobilization of several phosphonic acids and phosphoric acid esters on various
    mesoporous silicas in a Dean–Stark apparatus with toluene as the solvent. Due
    to the utilization of azeotropic distillation, there was no need to dry phosphonic
    acids, phosphoric acid esters, solvents, or silicas prior to synthesis. In addition
    to modeling phosphonic acids, immobilization of the important biomolecule adenosine
    monophosphate (AMP) on the porous supports was also investigated. Due to the high
    surface area of the mesoporous silicas, a possible catalytic application based
    on immobilization of an organocatalyst for an asymmetric aldol reaction is discussed.</jats:p>
article_number: '249'
article_type: original
author:
- first_name: Christian
  full_name: Weinberger, Christian
  id: '11848'
  last_name: Weinberger
- first_name: Tatjana
  full_name: Heckel, Tatjana
  last_name: Heckel
- first_name: Patrick
  full_name: Schnippering, Patrick
  last_name: Schnippering
- first_name: Markus
  full_name: Schmitz, Markus
  last_name: Schmitz
- first_name: Anpeng
  full_name: Guo, Anpeng
  last_name: Guo
- first_name: Waldemar
  full_name: Keil, Waldemar
  last_name: Keil
- first_name: Heinrich C.
  full_name: Marsmann, Heinrich C.
  last_name: Marsmann
- first_name: Claudia
  full_name: Schmidt, Claudia
  id: '466'
  last_name: Schmidt
  orcid: 0000-0003-3179-9997
- first_name: Michael
  full_name: Tiemann, Michael
  id: '23547'
  last_name: Tiemann
  orcid: 0000-0003-1711-2722
- first_name: René
  full_name: Wilhelm, René
  last_name: Wilhelm
citation:
  ama: Weinberger C, Heckel T, Schnippering P, et al. Straightforward Immobilization
    of Phosphonic Acids and Phosphoric Acid Esters on Mesoporous Silica and Their
    Application in an Asymmetric Aldol Reaction. <i>Nanomaterials</i>. Published online
    2019. doi:<a href="https://doi.org/10.3390/nano9020249">10.3390/nano9020249</a>
  apa: Weinberger, C., Heckel, T., Schnippering, P., Schmitz, M., Guo, A., Keil, W.,
    Marsmann, H. C., Schmidt, C., Tiemann, M., &#38; Wilhelm, R. (2019). Straightforward
    Immobilization of Phosphonic Acids and Phosphoric Acid Esters on Mesoporous Silica
    and Their Application in an Asymmetric Aldol Reaction. <i>Nanomaterials</i>, Article
    249. <a href="https://doi.org/10.3390/nano9020249">https://doi.org/10.3390/nano9020249</a>
  bibtex: '@article{Weinberger_Heckel_Schnippering_Schmitz_Guo_Keil_Marsmann_Schmidt_Tiemann_Wilhelm_2019,
    title={Straightforward Immobilization of Phosphonic Acids and Phosphoric Acid
    Esters on Mesoporous Silica and Their Application in an Asymmetric Aldol Reaction},
    DOI={<a href="https://doi.org/10.3390/nano9020249">10.3390/nano9020249</a>}, number={249},
    journal={Nanomaterials}, author={Weinberger, Christian and Heckel, Tatjana and
    Schnippering, Patrick and Schmitz, Markus and Guo, Anpeng and Keil, Waldemar and
    Marsmann, Heinrich C. and Schmidt, Claudia and Tiemann, Michael and Wilhelm, René},
    year={2019} }'
  chicago: Weinberger, Christian, Tatjana Heckel, Patrick Schnippering, Markus Schmitz,
    Anpeng Guo, Waldemar Keil, Heinrich C. Marsmann, Claudia Schmidt, Michael Tiemann,
    and René Wilhelm. “Straightforward Immobilization of Phosphonic Acids and Phosphoric
    Acid Esters on Mesoporous Silica and Their Application in an Asymmetric Aldol
    Reaction.” <i>Nanomaterials</i>, 2019. <a href="https://doi.org/10.3390/nano9020249">https://doi.org/10.3390/nano9020249</a>.
  ieee: 'C. Weinberger <i>et al.</i>, “Straightforward Immobilization of Phosphonic
    Acids and Phosphoric Acid Esters on Mesoporous Silica and Their Application in
    an Asymmetric Aldol Reaction,” <i>Nanomaterials</i>, Art. no. 249, 2019, doi:
    <a href="https://doi.org/10.3390/nano9020249">10.3390/nano9020249</a>.'
  mla: Weinberger, Christian, et al. “Straightforward Immobilization of Phosphonic
    Acids and Phosphoric Acid Esters on Mesoporous Silica and Their Application in
    an Asymmetric Aldol Reaction.” <i>Nanomaterials</i>, 249, 2019, doi:<a href="https://doi.org/10.3390/nano9020249">10.3390/nano9020249</a>.
  short: C. Weinberger, T. Heckel, P. Schnippering, M. Schmitz, A. Guo, W. Keil, H.C.
    Marsmann, C. Schmidt, M. Tiemann, R. Wilhelm, Nanomaterials (2019).
date_created: 2021-10-08T10:44:56Z
date_updated: 2023-03-08T08:32:12Z
department:
- _id: '35'
- _id: '2'
- _id: '307'
- _id: '315'
doi: 10.3390/nano9020249
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.mdpi.com/2079-4991/9/2/249/pdf?version=1550901386
oa: '1'
publication: Nanomaterials
publication_identifier:
  issn:
  - 2079-4991
publication_status: published
quality_controlled: '1'
status: public
title: Straightforward Immobilization of Phosphonic Acids and Phosphoric Acid Esters
  on Mesoporous Silica and Their Application in an Asymmetric Aldol Reaction
type: journal_article
user_id: '23547'
year: '2019'
...