---
_id: '27007'
abstract:
- lang: eng
  text: "<jats:title>Abstract</jats:title><jats:sec>\r\n                <jats:title>Purpose</jats:title>\r\n
    \               <jats:p>To examine the association between fructose intake in
    adolescence and fatty liver indices (hepatic steatosis index (HSI), fatty liver
    index (FLI)) in young adulthood.</jats:p>\r\n              </jats:sec><jats:sec>\r\n
    \               <jats:title>Methods</jats:title>\r\n                <jats:p>Overall,
    246 participants of the Dortmund Nutritional and Anthropometric Longitudinally
    Designed (DONALD) study who had a fasting blood sample in adulthood (18–36 years),
    at least two 3-day weighed dietary records for calculating fructose intakes and
    other fructose-containing sugars (total (TS), free (FS), added sugar (AS)) as
    well as two complete 24-h urine samples for calculating sugar excretion (fructose
    excretion (FE), fructose + sucrose excretion (FE + SE)) in adolescence (males:
    9.5–16.5 years; females: 8.5–15.5 years) were analysed using multivariable linear
    regression analyses.</jats:p>\r\n              </jats:sec><jats:sec>\r\n                <jats:title>Results</jats:title>\r\n
    \               <jats:p>On the level of dietary intake, no prospective associations
    were observed between adolescent fructose intake and both adult fatty liver indices,
    whereas higher FS intakes were associated with lower levels of HSI (<jats:italic>P</jats:italic><jats:sub>trend</jats:sub> = 0.02)
    and FLI (<jats:italic>P</jats:italic><jats:sub>trend</jats:sub> = 0.03). On the
    urinary excretion level, however, a higher FE (P<jats:sub>trend</jats:sub> = 0.03)
    and FE + SE (<jats:italic>P</jats:italic><jats:sub>trend</jats:sub> = 0.01) in
    adolescence were prospectively related to higher adult FLI values. No associations
    were observed between adolescent sugar excretion and adult HSI.</jats:p>\r\n              </jats:sec><jats:sec>\r\n
    \               <jats:title>Conclusion</jats:title>\r\n                <jats:p>The
    present study does not provide unambiguous support for a detrimental impact of
    adolescent fructose intake on adult liver health. Nonetheless, further examinations
    estimating exposure by means of urinary excretion as well as dietary intake levels
    appear warranted.</jats:p>\r\n              </jats:sec>"
author:
- first_name: Ines
  full_name: Perrar, Ines
  last_name: Perrar
- first_name: Anette
  full_name: Buyken, Anette
  id: '65985'
  last_name: Buyken
- first_name: Katharina J.
  full_name: Penczynski, Katharina J.
  last_name: Penczynski
- first_name: Thomas
  full_name: Remer, Thomas
  last_name: Remer
- first_name: Gunter G.
  full_name: Kuhnle, Gunter G.
  last_name: Kuhnle
- first_name: Christian
  full_name: Herder, Christian
  last_name: Herder
- first_name: Michael
  full_name: Roden, Michael
  last_name: Roden
- first_name: Karen
  full_name: Della Corte, Karen
  last_name: Della Corte
- first_name: Ute
  full_name: Nöthlings, Ute
  last_name: Nöthlings
- first_name: Ute
  full_name: Alexy, Ute
  last_name: Alexy
citation:
  ama: Perrar I, Buyken A, Penczynski KJ, et al. Relevance of fructose intake in adolescence
    for fatty liver indices in young adulthood. <i>European Journal of Nutrition</i>.
    Published online 2021:3029-3041. doi:<a href="https://doi.org/10.1007/s00394-020-02463-2">10.1007/s00394-020-02463-2</a>
  apa: Perrar, I., Buyken, A., Penczynski, K. J., Remer, T., Kuhnle, G. G., Herder,
    C., Roden, M., Della Corte, K., Nöthlings, U., &#38; Alexy, U. (2021). Relevance
    of fructose intake in adolescence for fatty liver indices in young adulthood.
    <i>European Journal of Nutrition</i>, 3029–3041. <a href="https://doi.org/10.1007/s00394-020-02463-2">https://doi.org/10.1007/s00394-020-02463-2</a>
  bibtex: '@article{Perrar_Buyken_Penczynski_Remer_Kuhnle_Herder_Roden_Della Corte_Nöthlings_Alexy_2021,
    title={Relevance of fructose intake in adolescence for fatty liver indices in
    young adulthood}, DOI={<a href="https://doi.org/10.1007/s00394-020-02463-2">10.1007/s00394-020-02463-2</a>},
    journal={European Journal of Nutrition}, author={Perrar, Ines and Buyken, Anette
    and Penczynski, Katharina J. and Remer, Thomas and Kuhnle, Gunter G. and Herder,
    Christian and Roden, Michael and Della Corte, Karen and Nöthlings, Ute and Alexy,
    Ute}, year={2021}, pages={3029–3041} }'
  chicago: Perrar, Ines, Anette Buyken, Katharina J. Penczynski, Thomas Remer, Gunter
    G. Kuhnle, Christian Herder, Michael Roden, Karen Della Corte, Ute Nöthlings,
    and Ute Alexy. “Relevance of Fructose Intake in Adolescence for Fatty Liver Indices
    in Young Adulthood.” <i>European Journal of Nutrition</i>, 2021, 3029–41. <a href="https://doi.org/10.1007/s00394-020-02463-2">https://doi.org/10.1007/s00394-020-02463-2</a>.
  ieee: 'I. Perrar <i>et al.</i>, “Relevance of fructose intake in adolescence for
    fatty liver indices in young adulthood,” <i>European Journal of Nutrition</i>,
    pp. 3029–3041, 2021, doi: <a href="https://doi.org/10.1007/s00394-020-02463-2">10.1007/s00394-020-02463-2</a>.'
  mla: Perrar, Ines, et al. “Relevance of Fructose Intake in Adolescence for Fatty
    Liver Indices in Young Adulthood.” <i>European Journal of Nutrition</i>, 2021,
    pp. 3029–41, doi:<a href="https://doi.org/10.1007/s00394-020-02463-2">10.1007/s00394-020-02463-2</a>.
  short: I. Perrar, A. Buyken, K.J. Penczynski, T. Remer, G.G. Kuhnle, C. Herder,
    M. Roden, K. Della Corte, U. Nöthlings, U. Alexy, European Journal of Nutrition
    (2021) 3029–3041.
date_created: 2021-10-29T13:48:27Z
date_updated: 2022-01-06T06:57:32Z
department:
- _id: '17'
- _id: '22'
- _id: '571'
doi: 10.1007/s00394-020-02463-2
language:
- iso: eng
page: 3029-3041
publication: European Journal of Nutrition
publication_identifier:
  issn:
  - 1436-6207
  - 1436-6215
publication_status: published
status: public
title: Relevance of fructose intake in adolescence for fatty liver indices in young
  adulthood
type: journal_article
user_id: '61597'
year: '2021'
...