---
res:
  bibo_abstract:
  - <jats:p> The effectiveness of whey protein plus potassium bicarbonate-enriched
    diet (WP+KHCO<jats:sub>3</jats:sub>) in mitigating disuse-induced changes in muscle
    fiber oxidative capacity and capillarization was investigated in a 21-day crossover
    design bed rest study. Ten healthy men (31 ± 6 yr) once received WP+KHCO<jats:sub>3</jats:sub>
    and once received a standardized isocaloric diet. Muscle biopsies were taken 2
    days before and during the 19th day of bed rest (BR) from the soleus (SOL) and
    vastus lateralis (VL) muscle. Whole-body aerobic power (V̇o<jats:sub>2 max</jats:sub>),
    muscle fatigue, and isometric strength of knee extensor and plantar flexor muscles
    were monitored. Muscle fiber types and capillaries were identified by immunohistochemistry.
    Fiber oxidative capacity was determined as the optical density (OD) at 660 nm
    of succinate dehydrogenase (SDH)-stained sections. The product of fiber cross-sectional
    area and SDH-OD (integrated SDH) indicated the maximal oxygen consumption of that
    fiber. The maximal oxygen consumption supported by a capillary was calculated
    as the integrated SDH in its supply area. BR reduced isometric strength of knee
    extensor muscles ( P &lt; 0.05), and the fiber oxidative capacity ( P &lt; 0.001)
    and V̇o<jats:sub>2 max</jats:sub> ( P = 0.042), but had no significant impact
    on muscle capillarization or fatigue resistance of thigh muscles. The maximal
    oxygen consumption supported by a capillary was reduced by 24% in SOL and 16%
    in VL ( P &lt; 0.001). WP+KHCO<jats:sub>3</jats:sub> attenuated the disuse-induced
    reduction in fiber oxidative capacity in both muscles ( P &lt; 0.01). In conclusion,
    following 19 days of bed rest, the decrement in fiber oxidative capacity is proportionally
    larger than the loss of capillaries. WP+KHCO<jats:sub>3</jats:sub> appears to
    attenuate disuse-induced reductions in fiber oxidative capacity. </jats:p>@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Alessandra
      foaf_name: Bosutti, Alessandra
      foaf_surname: Bosutti
  - foaf_Person:
      foaf_givenName: Michele
      foaf_name: Salanova, Michele
      foaf_surname: Salanova
  - foaf_Person:
      foaf_givenName: Dieter
      foaf_name: Blottner, Dieter
      foaf_surname: Blottner
  - foaf_Person:
      foaf_givenName: Judith
      foaf_name: Bühlmeier, Judith
      foaf_surname: Bühlmeier
      foaf_workInfoHomepage: http://www.librecat.org/personId=89838
  - foaf_Person:
      foaf_givenName: Edwin
      foaf_name: Mulder, Edwin
      foaf_surname: Mulder
  - foaf_Person:
      foaf_givenName: Jörn
      foaf_name: Rittweger, Jörn
      foaf_surname: Rittweger
  - foaf_Person:
      foaf_givenName: Moi Hoon
      foaf_name: Yap, Moi Hoon
      foaf_surname: Yap
  - foaf_Person:
      foaf_givenName: Bergita
      foaf_name: Ganse, Bergita
      foaf_surname: Ganse
  - foaf_Person:
      foaf_givenName: Hans
      foaf_name: Degens, Hans
      foaf_surname: Degens
  bibo_doi: 10.1152/japplphysiol.00936.2015
  bibo_issue: '4'
  bibo_volume: 121
  dct_date: 2016^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/8750-7587
  - http://id.crossref.org/issn/1522-1601
  dct_language: eng
  dct_publisher: American Physiological Society@
  dct_subject:
  - Physiology (medical)
  - Physiology
  dct_title: Whey protein with potassium bicarbonate supplement attenuates the reduction
    in muscle oxidative capacity during 19 days of bed rest@
...