{"language":[{"iso":"eng"}],"date_updated":"2023-02-06T12:49:55Z","type":"journal_article","publication":"Proceedings of the National Academy of Sciences","year":"2016","status":"public","intvolume":"       113","author":[{"first_name":"Carlos G.","last_name":"Lopez","full_name":"Lopez, Carlos G."},{"last_name":"Saldanha","full_name":"Saldanha, Oliva","first_name":"Oliva"},{"first_name":"Klaus","id":"237","last_name":"Huber","full_name":"Huber, Klaus"},{"first_name":"Sarah","full_name":"Köster, Sarah","last_name":"Köster"}],"publisher":"Proceedings of the National Academy of Sciences","volume":113,"title":"Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study","_id":"41838","department":[{"_id":"314"}],"publication_identifier":{"issn":["0027-8424","1091-6490"]},"user_id":"237","citation":{"bibtex":"@article{Lopez_Saldanha_Huber_Köster_2016, title={Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study}, volume={113}, DOI={<a href=\"https://doi.org/10.1073/pnas.1606372113\">10.1073/pnas.1606372113</a>}, number={40}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Lopez, Carlos G. and Saldanha, Oliva and Huber, Klaus and Köster, Sarah}, year={2016}, pages={11152–11157} }","chicago":"Lopez, Carlos G., Oliva Saldanha, Klaus Huber, and Sarah Köster. “Lateral Association and Elongation of Vimentin Intermediate Filament Proteins: A Time-Resolved Light-Scattering Study.” <i>Proceedings of the National Academy of Sciences</i> 113, no. 40 (2016): 11152–57. <a href=\"https://doi.org/10.1073/pnas.1606372113\">https://doi.org/10.1073/pnas.1606372113</a>.","short":"C.G. Lopez, O. Saldanha, K. Huber, S. Köster, Proceedings of the National Academy of Sciences 113 (2016) 11152–11157.","ama":"Lopez CG, Saldanha O, Huber K, Köster S. Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study. <i>Proceedings of the National Academy of Sciences</i>. 2016;113(40):11152-11157. doi:<a href=\"https://doi.org/10.1073/pnas.1606372113\">10.1073/pnas.1606372113</a>","mla":"Lopez, Carlos G., et al. “Lateral Association and Elongation of Vimentin Intermediate Filament Proteins: A Time-Resolved Light-Scattering Study.” <i>Proceedings of the National Academy of Sciences</i>, vol. 113, no. 40, Proceedings of the National Academy of Sciences, 2016, pp. 11152–57, doi:<a href=\"https://doi.org/10.1073/pnas.1606372113\">10.1073/pnas.1606372113</a>.","ieee":"C. G. Lopez, O. Saldanha, K. Huber, and S. Köster, “Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study,” <i>Proceedings of the National Academy of Sciences</i>, vol. 113, no. 40, pp. 11152–11157, 2016, doi: <a href=\"https://doi.org/10.1073/pnas.1606372113\">10.1073/pnas.1606372113</a>.","apa":"Lopez, C. G., Saldanha, O., Huber, K., &#38; Köster, S. (2016). Lateral association and elongation of vimentin intermediate filament proteins: A time-resolved light-scattering study. <i>Proceedings of the National Academy of Sciences</i>, <i>113</i>(40), 11152–11157. <a href=\"https://doi.org/10.1073/pnas.1606372113\">https://doi.org/10.1073/pnas.1606372113</a>"},"publication_status":"published","issue":"40","doi":"10.1073/pnas.1606372113","page":"11152-11157","abstract":[{"text":"<jats:title>Significance</jats:title>\r\n          <jats:p>The hierarchical assembly pathway of the cytoskeletal protein vimentin may be responsible for the astonishing mechanical properties of the emerging filaments, such as high flexibility and extensibility, and thus play a key role in cellular mechanics. A two-step assembly mechanism, involving a lateral and a subsequent elongational step, has been established; however, the elongational step could not be followed in solution. Here, we show direct in situ observation and modeling of the elongation reaction of the filaments on the relevant length and time scales, using time-resolved, multiangle static and dynamic light scattering. We thus achieve sufficient spatio-temporal resolution without the need of labeling, staining, or adsorption to substrates.</jats:p>","lang":"eng"}],"keyword":["Multidisciplinary"],"date_created":"2023-02-06T12:49:36Z"}