article published yes Sudipta Pramanik author Dennis Milaege author Maxwell Hein author 527710000-0002-3732-2236 Kay-Peter Hoyer author 48411 Mirko Schaper author 43720 9 department 158 department <jats:p>The effect of plaque deposition (atherosclerosis) on blood flow behaviour is investigated via computational fluid dynamics and structural mechanics simulations. To mitigate the narrowing of coronary artery atherosclerosis (stenosis), the computational modelling of auxetic and non-auxetic stents was performed in this study to minimise or even avoid these deposition agents in the future. Computational modelling was performed in unrestricted (open) conditions and restricted (in an artery) conditions. Finally, stent designs were produced by additive manufacturing, and mechanical testing of the stents was undertaken. Auxetic stent 1 and auxetic stent 2 exhibit very little foreshortening and radial recoil in unrestricted deployment conditions compared to non-auxetic stent 3. However, stent 2 shows structural instability (strut failure) during unrestricted deployment conditions. For the restricted deployment condition, stent 1 shows a higher radial recoil compared to stent 3. In the tensile test simulations, short elongation for stent 1 due to strut failure is demonstrated, whereas no structural instability is noticed for stent 2 and stent 3 until 0.5 (mm/mm) strain. The as-built samples show a significant thickening of the struts of the stents resulting in short elongations during tensile testing compared to the simulations (stent 2 and stent 3). A modelling framework for the stent deployment system that enables the selection of appropriate stent designs before in vivo testing is required. This leads to the acceleration of the development process and a reduction in time, resulting in less material wastage. The modelling framework shall be useful for doctors designing patient-specific stents.</jats:p> MDPI AG2023 eng Inorganic ChemistryCondensed Matter PhysicsGeneral Materials ScienceGeneral Chemical Engineering 2073-435210.3390/cryst13111592 1311 S. Pramanik, D. Milaege, M. Hein, K.-P. Hoyer, and M. Schaper, “Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach,” <i>Crystals</i>, vol. 13, no. 11, Art. no. 1592, 2023, doi: <a href="https://doi.org/10.3390/cryst13111592">10.3390/cryst13111592</a>. Pramanik, S., Milaege, D., Hein, M., Hoyer, K.-P., &#38; Schaper, M. (2023). Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach. <i>Crystals</i>, <i>13</i>(11), Article 1592. <a href="https://doi.org/10.3390/cryst13111592">https://doi.org/10.3390/cryst13111592</a> S. Pramanik, D. Milaege, M. Hein, K.-P. Hoyer, M. Schaper, Crystals 13 (2023). Pramanik, Sudipta, Dennis Milaege, Maxwell Hein, Kay-Peter Hoyer, and Mirko Schaper. “Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach.” <i>Crystals</i> 13, no. 11 (2023). <a href="https://doi.org/10.3390/cryst13111592">https://doi.org/10.3390/cryst13111592</a>. Pramanik, Sudipta, et al. “Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach.” <i>Crystals</i>, vol. 13, no. 11, 1592, MDPI AG, 2023, doi:<a href="https://doi.org/10.3390/cryst13111592">10.3390/cryst13111592</a>. @article{Pramanik_Milaege_Hein_Hoyer_Schaper_2023, title={Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach}, volume={13}, DOI={<a href="https://doi.org/10.3390/cryst13111592">10.3390/cryst13111592</a>}, number={111592}, journal={Crystals}, publisher={MDPI AG}, author={Pramanik, Sudipta and Milaege, Dennis and Hein, Maxwell and Hoyer, Kay-Peter and Schaper, Mirko}, year={2023} } Pramanik S, Milaege D, Hein M, Hoyer K-P, Schaper M. Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach. <i>Crystals</i>. 2023;13(11). doi:<a href="https://doi.org/10.3390/cryst13111592">10.3390/cryst13111592</a> 491072023-11-21T15:29:49Z2023-11-21T15:30:57Z